View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by VCU Scholars Compass Virginia Commonwealth University VCU Scholars Compass Theses and Dissertations Graduate School 2012 TOWARDS UNDERSTANDING THE MECHANISM OF ACTION OF ABUSED CATHINONES Rakesh Vekariya Virginia Commonwealth University Follow this and additional works at: http://scholarscompass.vcu.edu/etd Part of the Pharmacy and Pharmaceutical Sciences Commons © The Author Downloaded from http://scholarscompass.vcu.edu/etd/2841 This Thesis is brought to you for free and open access by the Graduate School at VCU Scholars Compass. It has been accepted for inclusion in Theses and Dissertations by an authorized administrator of VCU Scholars Compass. For more information, please contact
[email protected]. © Rakesh H. Vekariya 2012 All Rights Reserved TOWARDS UNDERSTANDING THE MECHANISM OF ACTION OF ABUSED CATHINONES A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science at Virginia Commonwealth University. by Rakesh Harsukhlal Vekariya B. Pharm., Dr. M.G.R. Medical University, Chennai, India 2008 Director: Dr. Richard A. Glennon Professor and Chairman, Department of Medicinal Chemistry Virginia Commonwealth University Richmond, Virginia July, 2012 ii Acknowledgment I would like to thank Dr. Glennon for giving me opportunity to work in his group. His constant support and encouragement throughout my program have been quite helpful. His suggestions and cooperation from the beginning of my project have been very valuable. I would like to thank Dr. Dukat for her guidance and encouragement as well as for creating a friendly work environment. I would like to thank Dr.