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50Th Anniversary of the Bereitschaftspotential Events Have Occurred VOL. 29 • NO. 3 • June 2014 THE OFFICIAL NEWSLETTER OF THE WORLD FEDERATION OF NEUROLOGY EXPeriments Into Readiness for Action INSIDE features 50th Anniversary of the IAPRD and PSN Join Hands: First Movement Disorder Course and Botox Workshop Bereitschaftspotential The specialty of neurology shows remarkable growth in last decade BY LÜDER DEECKE potential and a selection of the in Pakistan. special session inaugurated and main research results of our PAGE 2 chaired by Mark Hallett, Bethesda, experiments into readiness for Maryland, at the International action. A Neurology Cooperation Around Congress of Clinical Neurophysiology the World (ICCN2014) in March 2014 in Berlin The History of the Since I wrote my last column, many celebrated the 50th anniversary of the Bereitschaftspotential events have occurred. Bereitschaftspotential. The session in- In 1964, my mentor Hans Helmut PAGE 3 cluded lectures by Lüder Deecke, Vienna: Kornhuber (1928-2009) and I discovered “Experiments Into Readiness for Action — the readiness potential (Kornhuber and Bereitschaftspotential;” Hiroshi Shibasaki, Deecke, 1964). We submitted the full voluntary movement and named it the Stroke in Literary Works Around Akio Ikeda, Kyoto, Japan: “Generator paper in the same year. It was published Bereitschaftspotential (BP) or readiness the World Mechanisms of BP and Its Clinical Applica- in the first 1965 issue of “Pflügers Archiv” potential. (See Figure 1B.) There are few other neurological tion;” Gert Pfurtscheller, Graz, Austria: (Kornhuber and Deecke, 1965). The BP is the electrophysiological sign disorders with such a constant presence “Movement-Related Desynchronization We described a novel method, reverse of planning, preparation and initiation in literary works as apoplexy. and Resting State Sensorimotor Net- averaging, for recording brain electrical of volitional acts. How did the idea come PAGE 4 works;” and Ross Cunnington, Brisbane, activity prior to voluntary movement up to record brain potentials preceding Australia: “Concurrent fMRI-EEG and the in humans by noninvasive means and human voluntary movements in the EEG? Editor’s Update and Selected Bereitschafts-BOLD-Effect.” The session presented the first fundamental results It began on a Saturday in May 1964 when Articles From JNS was well accepted. obtained with this method. We found Kornhuber invited his doctoral student Check out the latest articles from the In this paper, I would like to give an that a negative electrical cortical po- L.D. for lunch into the ‘Gasthof zum Journal of Neurological Sciences. outline of the history of the Bereitschafts- tential consistently preceded human see BEREITSCHAFTSPOTENTIAL, page 6 PAGE 11 The World of Neurology Comes Together at the AAN Annual Meeting he 2014 Annual Meeting of the the Presidential Lecture on “Challenges tion of a unique basic and translational re- American Academy of Neurology to Ethics and Professionalism Facing the molecular and func- search, and innovative technical T (AAN) attracted more than 13,000 Contemporary Neurologist.” The George tional microglia sig- developments were shared and neurology professionals to Philadelphia, C. Cotzias Lecture featured Stefan M. nature in health and discussed at the Contemporary a city rich in its own neurology-related Pulst, MD, FAAN, speaking on “Degen- disease; emerging Clinical Issues Plenary Session. history. More than 2,500 presentations erative Ataxias: From Genes to Thera- concepts in chronic This year’s topics were acute of cutting-edge research were available pies.” The Sidney Carter Award in Child traumatic encepha- ischemic stroke, Friedreich’s to attendees from across the world. Neurology went to Darryl C. De Vivo, lopathy; functional ataxia, insomnia, epilepsy, func- The number of non-U.S. attendees was MD, FAAN, who expounded on “Rare connectivity and tional (psychogenic) disorders nearly 4,000. Diseases and Neurological Phenotypes.” functional imag- and the Parkinson’s disease Science and continuing medical educa- Finally, David M. Holtzman, MD, FAAN, ing in movement Progression Marker Initiative. tion are the main draws to the Annual shared “Alzheimer’s Disease in 2014: disorders; and the At the Frontiers in Trans- Meeting, and this year was no exception. Mapping a Road Forward,” as the Robert global epidemic in lational Neuroscience Plenary One of the highlights was the Presiden- Wartenberg lecturer. stroke. Session, attendees heard about tial Plenary Session, the AAN’s premier The Hot Topics Plenary Session Abstracts related the clinical aspects of tissue lecture awards for clinically relevant re- presented recent research findings and to new therapeutic environments for brain repair; search. James L. Bernat, MD, FAAN, gave clinical implications regarding identifica- developments, clinical applications of see ANNUAL MEETING, page 5 2 WWW.WFNEUROLOGY.ORG • JUNE 2014 From the Editor-IN-Chief International Colloquium that included topics such as “Dealing With Common Disorders With Limited Resources,” WORLD FEDERATION OF NEUROLOGY Editor in Chief The section elected Farrah Mateen “Successful Examples of International Donald H. Silberberg AAN Meeting from in the Department of Neurology Collaboration,” and Information on Assistant Editor at Massachusetts General fellowships in the U.S. An Keith Newton in Review Hospital as its new presi- Integrated Neuroscience Ses- WFN OFFICERS dent. If you are interested sion featured oral presenta- President Raad Shakir (United Kingdom) BY DONALD SIlbERBERG in seeing the activities of tions on the “Global Impact First Vice President William Carroll (Australia) Secretary-Treasurer General Wolfgang Grisold s an addendum to the report the Global Health Section, of Non-Communicable (Austria) from the American Academy contact Franziska Schwarz at Neurological Diseases,” with of Neurology in this issue, I Franziska [email protected]. poster sessions before and ELECTED TRUSTEES A Gallo Diop (Senegal) wish to add that in 2012 the AAN International activities after. Finally, an Ethics Collo- Gustavo Roman (USA) established a Global Health Section. during the Philadelphia quium included a presentation REGIONAL DIRECTORS At the section meeting during the meeting included: on “Clinical Trials Involving Mohamed S. El-Tamawy (Pan Arab) Timothy Pedley (North America) 2014 AAN meeting in Philadelphia, a conference titled DONALD H. International Subjects.” Richard Hughes (Europe) Jerome Chin, the outgoing presi- “Controversies in Global SIlbERBERG In these ways, the AAN Riadh Gouider (Pan Africa) Marco Tulio Medina (Latin America) dent of the section, announced that Health: Corticosteroids for is now playing an important Man Mohan Mehndiratta (Asia-Oceania) the section now has more than 300 Meningitis,” a seminar on role in global neurology EXECUTIVE DIRECTOR members, including many from “Global Health Challenges: together with the World Keith Newton outside the U.S. Neurology in Developing Countries,” an Federation of Neurology. • 1 Lyric Square Hammersmith, London W6 0NB, UK Tel: +44 (0) 203 542 7857/8 Fax: +44 (0) 203 008 6161 [email protected] IAPRD and PSN Join Hands: EDITOR OF THE JOURNAL and treatment while neurodegeneration OF THE NEUROLOGICAL SCIENCES John England (USA) in children: diagnostic issues in developing First Movement Disorder countries was presented by Tipu Sultan from Children Hospital Lahore. A unique and thought-provoking session of this was Course and Botox Workshop in the Neurology Training and Advo- WORLD NEUROLOGY, an official publication of the World Federation of Neurology, provides reports cacy session. This session highlighted the from the leadership of the WFN, its member BY AbDUL MALIK, MBBS, DCN, MD conference, the Sardar Alam, outgoing glimpses on post-graduate neurology in societies, neurologists around the globe and news from the cutting-edge of clinical neurology. Con- he specialty of neurology shows Pakistan Society of Neurology (PSN) Pakistan by Sarwar Siddiqi, psychiatric care tent for World Neurology is provided by the World remarkable growth in last decade in president, welcomed the delegates and and interface with neurology by Prof. Iqbal Federation of Neurology and Ascend Integrated Pakistan. The 21st meeting of the presented the report of the last two years Afridi, neurosurgery care and interface Media. T Disclaimer: The ideas and opinions expressed in Pakistan Society of Neurology (PSN) was of the society’s works. Prof. M. Wasay, with neurology by Prof. Junaid Ashraf and World Neurology do not necessarily reflect those of organized in collaboration with the Inter- chairman of the organizing committee, advocacy for neurological care in Pakistan the World Federation of Neurology or the publisher. The World Federation of Neurology and Ascend national Association of Parkinson’s and stated the statistics of neurology care and Prof. Rasheed Jooma. Integrated Media will not assume responsibility for Related Disorders (IAPRD) March 28-30 in neurologist in Pakistan. He said that for There were 15 original oral presenta- damages, loss or claims of any kind arising from or related to the information contained in this Karachi, Pakistan. every one million people only one neurolo- tions and 20 poster presentations from publication, including any claims related to the There were eight scientific sessions and a gist is available. all major institutes of the country. This products, drugs or services mentioned herein. half-day Botox Hands-On Workshop in this Editorial Correspondence: Send editorial correspon- conference. The
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