Human-Specific NOTCH-Like Genes in a Region Linked to Neurodevelopmental Disorders Affect Cortical Neurogenesis
bioRxiv preprint doi: https://doi.org/10.1101/221226; this version posted November 17, 2017. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC 4.0 International license. Human-specific NOTCH-like genes in a region linked to neurodevelopmental disorders affect cortical neurogenesis Authors: Ian T Fiddes1,12, Gerrald A Lodewijk2,12, Meghan Mooring1, Colleen M Bosworth1, Adam D Ewing1#, Gary L Mantalas1,3, Adam M Novak1, Anouk van den Bout2, Alex Bishara4, Jimi L Rosenkrantz1,5, Ryan Lorig-Roach1, Andrew R Field1,3, Maximilian Haeussler1, Lotte Russo2, Aparna Bhaduri6, Tomasz J. Nowakowski6, Alex A. Pollen6, Max L. Dougherty7, Xander Nuttle8, Marie-Claude Addor9, Simon Zwolinski10, Sol Katzman1, Arnold Kriegstein6, Evan E. Eichler7,11, Sofie R Salama1,5,13, Frank MJ Jacobs1,2,13.14*, David Haussler1,5,13,14* Affiliations: 1 UC Santa Cruz Genomics Institute, Santa Cruz, California, United States of America, 2 University of Amsterdam, Swammerdam Institute for Life Sciences, Amsterdam, The Netherlands 3 Molecular, Cell and Developmental Biology, of California Santa Cruz, Santa Cruz, California, United States of America 4 Department of Computer Science and Department of Medicine, Division of Hematology, Stanford University, California, USA 5Howard Hughes Medical Institute, University of California Santa Cruz, Santa Cruz, California, United States of America 6The Eli and Edythe Broad
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