FULL CIRCLE KIDNEY DIALYSIS REVOLUTIONIZING Superman’s Director Report toDonors ALSO INTHISISSUE Cystic Fibrosis Breakthrough Takes Flight 2014–2015

VOL. 38, NO. 2 FALL 2015

A LIFE OF SERVICE

HIRLEY VAUGHN believed in community. SShe volunteered at the library, the hospital and the local chamber of commerce. She knitted caps for a youth center. When her daughter, Joyce Kirk, was diagnosed with multiple sclerosis (MS) in 1998, it’s no surprise that Shirley found a way to take action, even from across the country. “She had an opportunity to make a gift to UW Medicine, with the hope of helping not only me, but other people with MS,” says Joyce. Going green. Shirley passed away in 2014 at the age of 87. And with a Rather read UW Medicine online? bequest made to MS research, she’s still making a difference Want to save resources? Send your full name and email (and your spouse’s in our community. or partner’s name and email) to [email protected]. Mention the If you’d like to learn more about leaving a gift in your will magazine. Next time, you’ll get an email notification rather than a print to benefit research, education or patient care, contact publication. Thank you! Mary Susan Wilson at 206.221.6172 or visit supportuwmedicine.org/planned-giving. A magazine for alumni and friends of the University of Washington School of Medicine

Contents VOL. 38, NO. 2 I FALL 2015

FEATURES Full Circle: Revolutionizing Winning the Race Against Kidney Dialysis . . . . .8 Cystic Fibrosis . . . . .12

TOP OF MIND Superman’s director takes flight; plans for diversity; babies and hypothermia; students and global health; specimens and science ...... 15

REPORT TO DONORS Advancing palliative care, understanding Alzheimer’s, promoting sports safety, recognizing faculty, supporting students and patients; our donors were key in 2014–15 . . . . . 19

AND MORE Messages ...... 3 Alumni and ClassNotes ...... 36 Student Updates . . . . .30 Around UW Medicine . . . 5 Passages ...... 46 Seen & Heard ...... 34 MEDEX Northwest . . . .29 Student Voices . . . . . 52

Visit UW Medicine online at uwmedmagazine.org for more »

“Stuart Farber taught me a lot about the principles of palliative care. The No. 1 thing Stu taught me is: when you meet a patient, look them in the eye, and have them tell you their story. You’ll hear a narrative critical to your role in meeting their needs.”

Michael Linenberger, M.D., Fel. ’89 Stuart Julian Farber, M.D. ’74 Read more on pages 22 and 27.

FALL 2015 1 “I’m still rescuing others thanks to UW MEDICINE Dean’s Office UW Medicine.” - Ken Knott UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE Paul G. Ramsey, M.D. CEO, UW Medicine Executive Vice President for Medical Affairs and Dean of the School of Medicine, University of Washington Don Theophilus Chief Advancement Officer, UW Medicine, and Vice President for Medical Affairs, University of Washington [email protected]

UW Medicine Alumni Association EXECUTIVE COMMITTEE President Scott R. Stuart, M.D. ’01, Res. ’04, Chief Res. ’05 Past President Angela J. Chien, M.D. ’95 Ex Officio Werner E. Samson, M.D. ’53, Res. ’58, Faculty Liaison Carol C. Teitz, M.D., Res. ’80, Dean’s Liaison Caroline M. Anderson, Dean’s Liaison

UW School of Medicine Alumni Relations Director Lynne Salkin Morris [email protected] Coordinator Katelin Cannon [email protected]

MEDEX Northwest [email protected] Interim Section Chief Linda Vorvick, M.D. ’82, Res. ’85 [email protected] Program Director Terry Scott, MPA, PA-C (Seattle Class 25) [email protected]

UW Medicine Magazine uwmedmagazine.org Editor Delia Ward [email protected] Writers Eleanor Licata and Sandy Marvinney Graphic Designer Ann Wolken Web Designer Stefanie Starkovich Photographers Clare McLean and David Wentworth Production Manager Anne Totoraitis Contributors Caroline Anderson, Steven Campbell, Katelin Cannon, Jennifer Hazelbrook, Lynne Salkin Morris, Natalie Rasmussen, Dennis Raymond, Anne Totoraitis, Marjorie Wenrich and UW Medicine Strategic Marketing & Communications Printing Coordinated by University of Washington Creative + Communications

Phone: 206.685.1875 Toll free: 1.866.MED.ALUM (1.866.633.2586) Fax: 206.685.9889 Email: [email protected] Web: uwmedalumni.org supportuwmedicine.org Address: UW Medicine Advancement uwmedicine.org/stories Box 358045 Seattle, WA 98195-8045 < Messages

DIVERSITY AND INCLUSION

We are in a new era of medicine and medical education. The stories in this issue portray remarkable new treatments and medical devices to prolong and improve lives. Our new medical-student curriculum is a 21st-century curriculum, featuring an integrated approach, active learning, a focus on lifelong learning, and greater clinical involvement from the start of medical school. I would like to highlight one vital area of emphasis for the UW School of Medicine — building a diverse health workforce to serve all our patients. At UW Medicine, we are committed to recruiting and sustaining a diverse and inclusive community of faculty, Photo: Clare McLean staff and learners. This summer, Leo Morales, our chief diversity officer and I had the honor to be featured speakers at the Association for American Indian Physicians’ 44th Annual Meeting and National Health Conference (see page 6). There, we affirmed our strong commitment to recruit more students and trainees from diverse backgrounds, including American Indian students. Dr. Morales has been with UW Medicine for a relatively short period of time but has already had a terrific impact. Recently, he announced the receipt of a federal award that will help build a pipeline of talented, diverse young people who will enter health careers; this is a vital part of fulfilling our mission. Congratulations to Dr. Morales and the entire Center for Health Equity, Diversity and Inclusion team for their work on behalf of a diverse workforce. You can read more about these efforts on page 16. There is much work yet to do. We have the right people and community to move us forward and an abiding commitment. Thank you to alumni, faculty, staff, students, trainees and friends for your efforts on behalf of building a diverse health workforce. Our future depends on it.

Sincerely,

Paul G. Ramsey, M.D. CEO, UW MEDICINE EXECUTIVE VICE PRESIDENT FOR MEDICAL AFFAIRS AND DEAN OF THE SCHOOL OF MEDICINE, UNIVERSITY OF WASHINGTON

FALL 2015 3 Messages >

OUR NEW PRESIDENT

I’m Scott Stuart, and it is my privilege to serve as the new president of the UW School of Medicine Alumni Association. I am a proud graduate of the University of Washington, earning a B.S. in zoology in 1992, an M.D. in 2001, and completing my internal medicine residency and chief residency in 2004 and 2005, respectively.

Photo: Team Photogenic Photo: Team My involvement with the University and the School hasn’t stopped since the day I enrolled, and I look forward to serving in this new capacity. Mission Statement For the past 10 years, I have worked as an internal medicine hospitalist at EvergreenHealth Medical Center in Kirkland. For eight of those years, I have been a The UW School of Medicine clinical instructor of medicine, and I have served as the site coordinator for the UW Alumni Association advances internal medicine clerkship for the past four. I thoroughly enjoy working with students UW Medicine’s mission to and have found my work as a clinical faculty member energizing. It helps me keep in improve the health of the touch with my alma mater, and getting to know the future physicians who will be serving public by: and leading in our communities inspires my confidence in the future of medicine. » Creating a global community In addition to my involvement with the School, I serve on the UW Alumni Association’s of alumni, faculty and (UWAA) legislative action committee. Through this group, I have developed a greater students that fosters lifelong understanding of the issues in our state surrounding higher education in general and engagement with one medical education in particular. Through my work on the legislative committee, I know another and the that the legislature has been supportive of the University of Washington, and I thank UW School of Medicine; them for the support. » Providing meaningful However, we face important challenges in Washington state when it comes to ensuring opportunities for advocacy and volunteerism; and that we have a robust physician workforce, particularly in rural and underserved areas. We not only need to increase the number of medical students we are educating, but » Fostering a culture of we also must expand the number of residency slots available in our region in order to philanthropy. provide more care to more patients. Doing so is the only way we will be able to meet the growing challenge of providing state-of-the-art medical care to citizens in our Vision region, regardless of where they live. I encourage all of you to take an active role in our To be a vital partner in UW School of Medicine Alumni Association so that we can work together to serve the UW Medicine’s success by needs of the Pacific Northwest. having an informed, engaged Thank you for the opportunity to serve as the president of the UW School of Medicine and active alumni community. Alumni Association. I look forward to continuing the work of Dr. Angela Chien and the Values Alumni Leadership Council, and to finding new ways to keep more alumni involved in the life of the School. I welcome your comments and suggestions. Advocacy Collaboration Communication Diversity Excellence Generosity Inclusivity Innovation Scott R. Stuart, M.D. ’01, Res. ’04, Chief Res. ’05 Mentorship PRESIDENT, UW SCHOOL OF MEDICINE ALUMNI ASSOCIATION, [email protected] Service P.S. For more information, visit uwmedalumni.org, or contact our alumni relations staff at 206.685.1875, toll free at 1.866.633.2586, or [email protected].

4 UW MEDICINE < Around UW Medicine: News

Patient Care Also see the Top of Mind section on page 15 for more stories. UW Medicine hospitals ranked high by U.S. News & World Research the senior author. Their findings were Report reported in Nature Genetics. In related UW Medical Intranasal insulin news, UW Medicine investigators will Center (UWMC), may mitigate be part of a new multi-center study to Harborview Medical Center and memory loss identify biological markers in children Valley Medical Center were all recog- Researchers with autism spectrum disorder. Identi- nized in U.S. News & World Report’s at UW Medicine, fying biomarkers will help physicians 2015–2016 “Best Hospitals” rankings. the VA Puget make early diagnoses and find the most UWMC ranked No. 1 in Seattle and Sound Health Care effective treatment for each patient. No. 1 in Washington state. Several of System and Saint Louis University UWMC’s specialty areas — rehabili- have discovered that insulin delivered Cancer cells, tation and cancer — were ranked in high up in the nasal cavity goes to the communicating the top 10 nationally, and neurology brain — not the bloodstream — and Cells dying and neurosurgery received a national aids memory function. This discovery from radiation “high-performing” designation. could benefit the estimated 44 mil- exposure or Valley Medical Center ranked No. 4 lion people worldwide suffering from chemotherapy can in Seattle and No. 6 in the state, and Alzheimer’s disease or other forms of release a protein that Harborview ranked No. 6 in Seattle dementia. William Banks, M.D., binds to nearby mother stem cells, and No. 11 in the state. Additionally, UW professor of medicine, is the allowing them to survive until they Harborview performs high in principal investigator of this study, can reproduce and regenerate tissue. orthopaedics nationally. published in the Journal of Alzheimer’s This process aids the body in growth Disease. Read more about Alzheimer’s and recovery. Researchers believe a UW Medicine pioneers research on page 26. similar process is at work with cancer stroke-fighting heart cells: dying daughter cells send protec- device Autism: clues to tive warnings to tumor-initiating cells, The UW Medicine risk and diagnosis enabling their survival and the return Regional Heart A new study that of cancer. By blocking these signals, Center is one of included 2,377 more effective cancer drugs could the first programs in children with be developed. Yalan Xing, Ph.D., a the nation to deploy the autism, their parents postdoctoral fellow in the departments “Watchman,” a device that prevents and their siblings finds of biology and genome sciences, is the strokes. The Watchman is designed for evidence of inherited genetic risk, lead author of the study, published in people with atrial fibrillation, a condi- especially between mothers and sons. Nature Communications, and Hannele tion in which the heartbeat quickens Mothers who harbor certain gene Ruohola-Baker, Ph.D., UW professor and goes out of sync, possibly leading mutations that produce abnormal of biochemistry and associate director to blood clots which can travel to the proteins remain unaffected, but pass of the UW Institute for Stem Cell brain and cause a stroke. The device along an increased risk of autism to and Regenerative Medicine, is the forms a permanent, protective barrier, their male offspring. Niklas Krumm, senior author. stopping blood clots from forming. Ph.D. ’14, and Tychele Turner, Ph.D., researchers in the Department of Genome Sciences, were lead authors of the study; Evan Eichler, Ph.D., UW professor of genome sciences, was

FALL 2015 5 Around UW Medicine: News >

Health Care A federal WWAMI Authority award aims to chooses close the First Alaska UW Medicine diversity gap track pediatric to offer new in the health residents healthcare option professions complete The Washington The UW School of Medicine’s training Health Care Authority Center for Health Equity, Diversity The Alaska has chosen the UW Medicine and Inclusion (CEDI) and the track of the University Accountable Care Network as a new UW Office of Minority Affairs and of Washington Pediatric Residency healthcare option for employees in Diversity received a grant totaling Program graduated its inaugural group the Public Employees Benefit nearly $2 million from the federal of primary-care physicians: Patti Clay, Board program. The state chose government for a project called the M.D., Res. ’15, Theresa Dulski, M.D., UW Medicine’s network to help UW Health Professions Academy. Res. ’15, Eric Foote, M.D., Res. ’15, achieve the goal of better health, This project will prepare under- and John Hawes, M.D., Res. ’15. better care and lower costs for graduate students from disadvantaged During their residency training, these its employees. backgrounds with the skills and experi- doctors spent four months each year ences to compete for entry into health for the past three years in Fairbanks, Education professions schools, with the aim of Anchorage and Bethel, while travel- closing the diversity gap in the health ing to see patients in remote villages. University of professions workforce and improving Alaska has a chronic shortage of Washington health access. Leo Morales, M.D. ’90, physicians and ranks near the bottom No. 3 in MPH, Ph.D., chief diversity officer in the U.S. in its pediatrician-to-child the world and director for CEDI, will lead the ratio. The Alaska track is a possible The University project. Read more about Morales and model for residencies in other fields of Washington was CEDI on page 16. facing shortages of rural physicians. again ranked No. 3 in the world in “clinical medicine and Expert mentors pharmacy,” by the Academic Ranking recognized of World Universities (ARWU), Congratulations compiled by researchers at the Center to Wylie Burke, for World-Class Universities at Ph.D. ’74, M.D. Shanghai Jiao Tong University in ’78, Res. ’81, China. More than 1,000 universities Fel. ’82, and Dawn are evaluated every year as institu- Ehde, M.D., Res. ’00, Ph.D., the Photo: Maggie Keelan tions overall and by five broad subject recipients of the 2015 UW Medicine A legacy of wisdom, areas, including clinical medicine and Excellence in Mentoring Award, a future of excellence pharmacy. which recognizes the vital impor- Two UW Medicine representatives — tance of mentoring faculty, especially CEO Paul G. Ramsey, M.D., and Leo women. Burke is a UW professor in Morales, M.D. ’90, MPH, Ph.D., chief the Department of Bioethics and Hu- diversity officer — were pleased to be manities, and Ehde is a UW professor featured speakers at the Association for in the Department of Rehabilitation American Indian Physicians’ (AAIP’s) Medicine. In addition, congratula- 44th Annual Meeting and National tions go to Frederick Rivara II, M.D., Health Conference, held in July in MPH, UW professor in the Marysville, Wash. The conference’s Department of Pediatrics, the 2015 theme was “coming back to the heart recipient of the UW Minority Faculty of medicine: a legacy of wisdom, a Mentoring Award. future of excellence,” and it was attended by approximately 300 people.

6 UW MEDICINE < Around UW Medicine: News

Notable Bearing witness: UW Medicine Donald Reay honored launches institute Jay Shendure “I’m not a witness for the defense or with help of NFL, appointed to for the prosecution. I am a witness for community national panel the dead.” So said Donald Reay, M.D., Earlier this Earlier this UW professor emeritus in fall, the National year, the Obama pathology and former King County Football League made administration medical examiner, in an interview with a contribution to help announced the The Seattle Times. Reay, known locally establish the UW Medicine creation of the Precision Medicine and nationally for his objectivity, intel- Sports Health and Safety Institute at Initiative, an effort to create more ligence and curiosity, will receive the Harborview Medical Center. And on precise and varied treatments for Milton Helpern Laureate Award this Oct. 10, 2015, a generous human illness, especially cancer. As fall from the National Association of community — at a benefit held for a part of the initiative, Jay Shendure, Medical Examiners. Read more about the institute — came together to raise M.D., Ph.D., UW professor of genome his life and work at seattletimes.com; even more, for a total of more than sciences, was appointed to the search for “Reay.” $9.25 million. The institute aims to Precision Medicine Initiative advance research, education and Working Group, which advises the UW Medicine advocacy to prevent sports-related director of the National Institutes of professor concussions and to study how to make Health. The group was charged with awarded global sports and activities safer for all developing a framework to create a honor for athletes. Read more about the institute cohort of approximately 1 million cell signaling on page 24. Americans willing to share medical discovery and other information to inform major Peter Greenberg, Ph.D., UW professor of microbiology, research efforts into illness and Want more news? » precision medicine. Their first report, is one of two researchers awarded the uwmedicine.org issued this September, includes sugges- prestigious 2015 Shaw Prize in life tions on recruitment, data collection sciences and medicine. He shares the and other topics. $1 million award with Bonnie Bassler Want more information on your health? » of Princeton University. The two are healthlibrary.uwmedicine.org being honored for elucidating the an A to Z guide on medical conditions molecular mechanism of “quorum uwmedicinehealth.com tips and videos sensing,” a process whereby bacteria uwmedicine.org/pulse podcasts communicate with each other and which offers innovative ways to interfere with bacterial pathogens or to modulate the microbiome for health applications.

FALL 2015 7 Feature > FULL CIRCLE REVOLUTIONIZING KIDNEY DIALYSIS By Sandy Marvinney

earing your heart on your sleeve: an old poetic idiom Wand a physical impossibility. Wearing your kidney on your belt? A life-saving idea that is now being tested. A wearable artificial kidney (WAK) is a decades-old concept, impractical to develop until the advent of novel tech- nologies and new biomaterials. This spring, UW Medicine and its collaborators concluded the first U.S. trials of a WAK prototype. The goal is to develop more effective dialysis therapies for thousands of people with kidney failure.

8 UW MEDICINE < Revolutionizing Kidney Dialysis Photo: Stephen Brashear

WHY DO WE Today. In the U.S., more than The WAK. It’s a 10-pound, The challenge. The team that NEED A WAK? 90 percent of dialysis patients battery-powered device worn worked on the trial was only The wearable artificial kidney visit centers several times a on a belt. It provides around- one of three chosen nation- (WAK) is a new way to do week for four to five hours the-clock, continuous dialysis. wide by the FDA for its dialysis. simply to stay alive; others do The potential. The WAK may Innovation Challenge — a dialysis at home using smaller offer thousands of people a pilot program for innovative The patients. Nearly half a machines. more normal life, more mobil- devices that address end-stage million people in the U.S. have ity and better health. renal disease as part of the kidney failure; about 400,000 FDA Innovation Pathway 2.0. are on dialysis.

Fighting an epidemic Then there are the costs. “It’s one A breakthrough technology Kidney disease is an irreversible of the most expensive chronic Worn on the belt, the WAK is a condition and the eighth leading cause diseases — it costs more than miniature, battery-powered dialysis of death in the U.S. $32 billion annually to treat the half- machine, connected to the patient “Chronic kidney disease is a huge million end-stage patients in the U.S.,” via a catheter. New technology has public health problem,” says Jonathan says Himmelfarb. Federal and state made the WAK possible: lighter, better Himmelfarb, M.D., UW professor of budgets carry most of the financial batteries; more advanced plastics; the medicine in the Division of Nephrol- burden. invention of a pump that manages ogy, director of the Kidney Research Patients’ survival depends on water and blood flow differently than Institute and holder of the Joseph W. long-term dialysis or transplant, but in other machines; the use of certain Eschbach, M.D. Endowed Chair in neither solution is perfect. With sorbents and enzymes to clean the Kidney Research. “About 20 million dialysis, patients in their twenties have dialysis fluid. people in the U.S. have chronic just a 20-year life expectancy. Even a In a word, freedom. “The WAK kidney disease.” transplant is no guarantee; they may allows patients to receive continuous And the problem, unfortunately, function only 10 years or so, hemodialysis, while going about their is not going away. According to requiring another transplant or a daily activities,” says Himmelfarb. And, Himmelfarb, new cases are increasing return to dialysis. because the machine works continu- every year, a byproduct of the aging of “We need breakthrough treatment ously, it should act more like a real set of the population and the rising preva- technologies,” says Himmelfarb. kidneys: constantly cleaning the blood lence of diabetes and hypertension, Technologies like the WAK. so that patients will start to feel a marked which damage the kidneys. improvement in their health.

FALL 2015 9 Revolutionizing Kidney Dialysis >

“Chronic kidney disease is a huge public health problem.”

— Jonathan Himmelfarb, M.D. Photo: Clare McLean

THE LIFE-SAVING The WAK’s first clinical trial Refining the WAK SCRIBNER-QUINTON SHUNT took place at UW Medical Center in Many clinical studies worldwide End-stage kidney disease was a Seattle, and the team of collaborators indicate that more frequent dialysis death sentence — until the creation included Himmelfarb and Victor Gura, improves patient health, which of the Scribner-Quinton shunt at M.D., the device’s developer makes the WAK a very promising UW Medicine in 1960. The inven- and founder of Blood Purification development for patient treatment. tion made long-term kidney dialysis possible. Developed by two innova- Technologies, Inc. (BPT), the early- Its developers hope that it also lowers tors, UW Medicine researcher and stage technology company that is the cost of healthcare. patient advocate Belding Scribner, producing the prototype. Larry Kessler, Himmelfarb can’t say too much M.D., and engineer and UW profes- Ph.D., chair of the Department of about the trial’s results; as of press time, sor Wayne Quinton, the shunt was Health Services at the UW School of a U-shaped, Teflon-coated tube they were being submitted for publica- installed in the arm for easy hook- Public Health, monitored the patient tion. But he’s decidedly positive. up to a dialysis machine. Prior to experience and the project’s regula- the shunt, physicians had to destroy tory aspects. In all, the trial took six “This was a pilot study,” he says. blood vessels each time dialysis was months and involved seven patients. “We are very hopeful that there will be performed, limiting the number of ongoing trials that will help to make treatments to five or seven. And “From the patient perspective, the this a potential reality for patients.” while Scribner and Quinton initially wearable artificial kidney could be the chose a TeflonTM coating because most significant technology advance The next steps will include refining they thought it wouldn’t react to since the development of long-term the prototype and making technical patient tissue, the material’s most dialysis methods in the 1960s,” says improvements. The team also plans to important benefit became obvious conduct several years of clinical testing later on. In an interview with the Himmelfarb. to assess potential benefits, risks and UW, Scribner reported, “It was only much later that we found out it was cost-effectiveness. the nonstick properties of TeflonTM that really made the shunt work… without the nonstick surface, the shunt always clotted.” In enabling long-term dialysis, the shunt — and the refinements that followed — have extended millions of lives.

10 UW MEDICINE < Revolutionizing Kidney Dialysis

A GOOD PAIR: NORTHWEST KIDNEY CENTERS AND UW MEDICINE In developing the life-saving Scribner-Quinton shunt, Belding Scribner, M.D., made long-term dialysis possible. And in founding Northwest Kidney Centers, the first outpatient dialysis program in the world, he made possible another series of ground-breaking ventures. In 2008, Northwest Kidney Centers and the University of Washington created the Kidney Research Institute (KRI), now directed by Jonathan Photos: Stephen Brashear At left: Jonathan Himmelfarb, M.D. (left), unpacks the WAK for Victor Gura, M.D. Himmelfarb, M.D. The success of the (center), and Larry Kessler, Sc.D., UW professor of health services. At right: John Kundzins new institute, says Himmelfarb, is of Northwest Kidney Centers models the device. made possible by Northwest Kidney Centers’ philanthropy. “We have approximately 50 active clinical studies under way at the “We will take the research one step “It’s little paradoxical. Some people institute, and seed monies from at a time to make sure the device is have pointed out that development Northwest Kidney Centers have performing well,” Himmelfarb empha- of dialysis treatment preceded a good contributed to the majority of these sizes. “We don’t want to give patients understanding of the disease,” Him- studies,” he says. Himmelfarb lists a few high-potential projects: prevent- false hope, but we are dedicated to melfarb says. “We need a lot more ing acute kidney injury in children providing more treatment options in basic research on kidney function at undergoing open-heart surgery. the future.” the molecular and cellular levels to un- Educating patients more thoroughly to improve outcomes from the use He’s also considering how ongoing derstand the kidneys’ true complexity and to improve treatments for all types of home dialysis machines. Perform- research into kidney function might af- ing healthy lifestyle interventions and stages of kidney disease.” fect the development of the WAK and in people with moderate to severe other treatments. chronic kidney disease. Northwest Kidney Centers also has More online » contributed to fellowship funding, allowing the UW’s Division of Visit kri.washington.edu, and watch Himmelfarb’s presentation on another Nephrology and the KRI to attract innovation: the kidney on a chip. junior scientists. Himmelfarb notes that the clinical trial involving children and surgery, mentioned above, is led by a fellow. “Northwest Kidney Centers gave us the opportunity to foster a new “The WAK could be the most significant generation of dedicated, talented early-career investigators as well as the opportunity to pursue leading- technology advance since the development of edge research for people living with long-term dialysis methods in the 1960s.” kidney disease,” says Himmelfarb. “Without this collaboration,” he says, “the Kidney Research Institute ­— Jonathan Himmelfarb, M.D. simply would not exist today.”

FALL 2015 11 Feature >

WINNING the Race Against Cystic Fibrosis By Eleanor Licata

For decades, Bonnie Ramsey M.D., Res. ’79, has been dedicated to treating and researching cystic fibrosis. Photography Photo: David Wentworth

NEW DRUG is revolution- bringing the cystic fibrosis community for patients was short: limited to early izing treatment for cystic fibrosis that much closer to finding a cure. childhood. Today, life expectancy for a by treating the life-threatening CF patient is close to 40 years of age, The burden of cystic fibrosis diseaseA at its source, instead of simply a major improvement — one made More than 30,000 people in the addressing the symptoms. possible by inhaled antibiotics and U.S. and 70,000 worldwide have cystic other therapies. An improvement that “It’s a huge step to actually direct fibrosis (CF), a rare, life-threatening will be enhanced, hopes Ramsey, the drug at the protein to get it to genetic disease. by Orkambi. work more effectively,” says Bonnie The problem lies in a defective Ramsey M.D., Res. ’79, UW profes- protein that normally operates as a salt Living on borrowed time sor and vice chair for research in the channel. This defective channel in After training as a pediatrician at Department of Pediatrics. She’s also CF patients creates a salt imbalance, Boston Children’s Hospital, Ramsey the director of the Center for Clinical which makes the body’s mucus extra came to Seattle Children’s. Studying and Translational Research at Seattle thick and viscous. Over time, mucus cystic fibrosis was not in her plans. “I Children’s and the holder of the build-up in the lungs, pancreas and was planning on being a pediatric on- Bonnie W. Ramsey, M.D. Endowed other organs leads to persistent lung cologist. But I took a year off and was Chair in Cystic Fibrosis. infections and problems with digestion. asked to cover the CF clinic because A drug called Orkambi holds the These bacterial lung infections, called they were between physicians. And key; it corrects the malfunctioning pro- pulmonary exacerbations, require I just loved the patient population,” tein that causes cystic fibrosis in about multiple hospitalizations and pose one she says. half of the people with the disease. of the greatest threats to CF patients’ Nate Schmidt was one of Ramsey’s And as lead investigator for the phase lives. patients. Shortly after birth, he was di- III clinical trials of the drug, Ramsey When the Cystic Fibrosis agnosed with the most common type of played an instrumental role in the de- Foundation Patient Registry began CF. A medical resident called his par- velopment and approval of Orkambi — tracking data in 1966, life expectancy ents to tell them he probably wouldn’t

12 UW MEDICINE < Winning the Race Against Cystic Fibrosis

live past elementary school. “Thankfully, throughput screening. Using vast chemi- that wasn’t the case,” says Schmidt, now cal libraries, researchers used sophisticated, A Day in the Life 29 and working for Gilead, a biotech firm rapid-performance equipment to look for in Seattle. “But that was the prognosis at compounds that could correct the abnormal the time.” CF protein. The likelihood of them finding It was working with children like anything? “Worse than finding a needle in a Schmidt, living on borrowed time, that haystack,” Ramsey says. inspired Ramsey to change course and But high-throughput screening found develop a clinical research program the needle: several potential chemical around cystic fibrosis — and to become a compounds that could fix the malfunction. pediatric pulmonologist. Vertex Pharmaceuticals developed them into potentiators, which open the CF Cystic fibrosis The needle in the haystack protein so it can work as a salt channel, and patient Nathan Schmidt When the gene responsible for cystic correctors, which help the CF protein fold describes his daily fibrosis was discovered in 1989, a wealth and get to the cell surface. routine — and an of new information on the disease began argument for more to pour in. Researchers found more than Orkambi is a combination of a potentia- and better treatments for CF. 1,800 different kinds of mutations in the tor called Kalydeco, which dramatically CF gene with different effects on the CF improves lung function for about 5 percent When I get up in protein. Some mutations don’t make the of patients with CF, and a corrector called the morning, I inhale several medications, CF protein at all. Others make a protein lumacaftor. This new drug combination, Orkambi, is designed to treat people with including saline. I also that misfolds, and some mutations make take medication to help proteins that fold, but are unable to open two copies of the F508del mutation — the me digest fats and pro- once they reach the cell surface. most common type of cystic fibrosis, teins, and I do physical affecting around half of the people who therapy — I blow into Different forms of the disease would suffer from the disease. a device that shakes require different approaches, researchers the air in my lungs and realized. In order to be effective, therapies Before Orkambi could be approved by allows me to cough up would need to be directed toward specific the FDA, it had to be proved safe and mucus. Otherwise, it would collect and lead genotypes. Much more research would effective through clinical trials. This was to infections. need to be done to create treatments that the challenge Ramsey and her team faced: would work for individual patients, and how to translate discoveries made in the lab Exercise is definitely into safe products for patients. recommended. I bike, Ramsey was part of that work. run and rock climb. In 1997, the Cystic Fibrosis Crossing the finish line Growing up, I had to Foundation asked Ramsey to put together Working with the Cystic Fibrosis do 45-minute sessions a clinical trials network. The following Foundation and Vertex Pharmaceuticals, of physical therapy year, with funding from the foundation Ramsey and her team helped design and several times a day to loosen the mucus. and the National Institutes of Health, conduct several phase III double-blind, Self-care gets harder Ramsey created the Therapeutic placebo-controlled clinical trials for in college because Development Network, which she helped Orkambi, involving more than 1,100 people you’re experiencing build into the largest CF clinical trials with CF. Participants, age 12 and older, independence for the network in the world. came from multiple countries. first time. Then, if you have a full-time job, “We started developing a whole new “Long before any promising drugs had it’s difficult to find the range of therapies and working with been identified, we were thinking, ‘What do time. You might have companies to get them interested in cystic we have to do to be ready?’” Ramsey says. to sacrifice things like fibrosis,” Ramsey says. “I thought of it like a relay. Our group was sleep, friends or even work. Around the same time, the Cystic the last ‘runner’ in the relay. So you’re Fibrosis Foundation provided grants to waiting for the baton to come, but then several laboratories to begin high- you’ve got to go finish the race.”

FALL 2015 13 Winning the Race Against Cystic Fibrosis >

Designing these clinical trials raised a lot of questions. What would they use to measure a change in salt production? How many patients would they include, and where would they find them? Perhaps most importantly, Ramsey says, “How are we going to know we’re there? That’s what’s Photo: Clare McLean really scary. You could have a ‘cure’ in the Nate Schmidt, 29, visits his physician, Moira L. Aitken, laboratory, but how are you going to detect M.D., at the UW Medicine Adult Cystic Fibrosis Clinic, one it to the point where the FDA will approve of the first of its kind in the nation. Schmidt was part of “Now, it, which is your ultimate goal?” the clinical trial for Orkambi. When Schmidt heard about the trial when I go from the UW Medicine Adult Cystic into the Fibrosis Clinic at UW Medical Center, he a longer life for many people with cystic lost no time signing up. The clinic, which fibrosis. Although it’s still too early to tell room... was recruiting patients for the trial, was what Orkambi’s full impact will be, it’s a established more than 25 years ago by his decided victory for everyone who’s worked I really can physician, Moira Aitken, M.D. Schmidt on the drug. enrolled in the study, and in October 2013, Ramsey stresses the importance of team- provide he participated in an extension study. He’s work in Orkambi’s development and approval: families with been taking Orkambi ever since. the Cystic Fibrosis Foundation, which has “I felt normal. I didn’t notice anything awarded approximately $25 million to UW hope.” different,” says Schmidt. But, he reasons, Medicine since 1988, played a vital role. As that’s probably what the drug is designed to did patients, industry and care teams. “I think do — keep you level and out of the hospital. it’s an example of when a whole lot of people work together for a common cause, you can — Bonnie Ramsey, “Most people with CF end up visiting really make a difference,” she says. M.D., Res. ’79 the hospital two to three times a year,” he says. “I haven’t been to the hospital for an Offering hope exacerbation in years. Fingers crossed it In the meantime, more research awaits. won’t happen any time soon.” There are still CF patients with gene mutations that aren’t addressed by any treatments on the The good news market. In July 2015, Orkambi received FDA approval. The results look good. Orkambi However, with the release of Kalydeco improved lung function around 2 to 4 in 2012 and Orkambi in 2015, more than percent — not a huge increase, but a 50 percent of CF patients have a new reason significant one. “But once you get that to hope. And so does Ramsey. improvement, [the patient is] stable for “I can remember sitting down with a family 12 months,” says Ramsey. “This is and feeling like I could provide comfort, but very encouraging.” not really hope,” Ramsey says. “And now when Stability, as Schmidt notes, is really I go into the room, it’s so different because I important to patients. One of the biggest really can provide them hope.” measures of improvement for people taking Schmidt is familiar with this feeling of Orkambi has been the striking decrease — cautious excitement. “Just about everybody around 40 to 60 percent — in the frequency with this disease is…watching the develop- of pulmonary infections. ment timeline of these products that come This means fewer hospitalizations for up,” he says. “We’re always cheering the patients, a better quality of life, and possibly team on.”

14 UW MEDICINE < Top of Mind

SUPERMAN’S DIRECTOR TAKES FLIGHT Photo: Clare McLean

ichard Donner — the director What do you like about How was this whole experience? of Superman: The Movie — took vacationing on Orcas Island? When we make movies, we make Rflight on Aug. 20, 2014. An It’s kind of a love story. I don’t a lot of demands on people, and it Airlift Northwest flight, that is. know if we found Orcas, or Orcas has to run smoothly. I would like to Donner went to Orcas Medical Center found us, but one way or another, it’s think that whatever I do next will with abdominal pain, their medical worked for 25 years. run as smoothly as everything did last staff promptly called Airlift Northwest, August. From my time at the clinic, to and our flying ICU took Donner to What happened last summer? the EMTs, to the Airlift flight, to the PeaceHealth St. Joseph Medical I felt very ill — I’d had the experi- hospital, it was extraordinarily well- Center in Bellingham, Wash. ence once before — so I went to Orcas organized and disciplined. It seemed Medical Center. The doctor was great. totally seamless. In addition to being a highly He did some quick tests: he knew the productive director and producer — symptoms, he knew the cause, and he One movie question: what’s his credits include Lethal Weapon, knew the answer. He thought I should rewarding about your job? The Goonies, and X-Men (a partner- be in a proper hospital, so he called I get a tremendous kick out of going ship with his wife, producer Lauren Airlift Northwest. The next thing I to a movie theater and trying to sit in Donner) — the 85-year-old Donner is knew, the EMTs were there, and then the very front row so I can look back quick with a comeback. the crew from Airlift. It all went so at the audience. We’re illusionists, and fast. I want to say it was a delightful we create illusions of love and laughter experience, but I hope I never do it and action and whatever. Watching again. the faces of the audience, I think, “wow, I did that.” It’s a wonderful How are you feeling today? feeling, especially if it’s joyful. (And a segue about helicopters.) I’m feeling great, but let me tell you something. I hate helicopters. Often, Learn more » while filming, I use choppers. I got To learn more about Airlift, including thrown off the pontoon of a helicopter its AirCare program and other and landed in the water. We lost a opportunities for partnership, please visit uwmedicine.org/airlift-nw. sliding door on a big one. So I’ve tried to stay away from helicopters until Airlift Northwest came into my life. I’m back to loving helicopters.

Richard and Lauren Donner

FALL 2015 15 Top of Mind >

HIS MOTHER’S SON REDEFINING INCLUSION WITH LEO MORALES

hen her son, Leo, went to 1982 and 2000) represent one-quarter California for residency, of the population, and 44.2 percent “Diversity and all the issues related to culture need to be front and center Gladys Romero went to work of them are part of a minority race or W and part of everything our organiza- for the U.S. Census. Her goal was to ethnic group. And when the Census is tion does,” says Leo Morales, encourage Latino participation, and extended to children age 5 and under, M.D. ’90, Ph.D., MPH, UW Medicine’s she got to know people — a lot of that number climbs to 50.2 percent. chief diversity officer. people in the state and region. “Many By 2050, America will have no clear times when I go into a community, I’m “majority” race/ethnic group. Developing a more diverse faculty introduced as my mother’s son,” says The corollary is simple: creating a pool. Many of the School’s residents Leo Morales, M.D. ’90, Ph.D., MPH, diverse workforce of doctors — for an become faculty, so programming that with a laugh. “It’s a more relevant increasingly diverse patient popula- pulls in and supports diverse residents introduction than any title I have.” tion — is good medicine. That’s why is key. A little over a year ago, Morales UW Medicine hired Morales: to figure Refining recruitment. Faculty are assumed several titles at UW Medicine, out how to recruit, retain and advance helping to develop and disseminate including chief diversity officer, director the careers of more students, trainees best practices that help the School of the Center for Health Equity, and faculty who will diversify that recruit diverse candidates during Diversity and Inclusion, and co-director workforce. How do Morales and his col- faculty job searches. of the Latino Center for Health. leagues intend to help the UW School Morales is optimistic about creating a Morales, who had been conducting of Medicine meet this challenge? By: more diverse and inclusive school — health disparities research for two Attracting more medical students in part because of the caliber of decades, first at UCLA then at the from diverse backgrounds from our faculty and students he’s met over the Group Health Research Institute, own region. “We need to think more past year. wanted a change of focus. “When about local colleges and universities,” “My impression is that people want Dr. Ramsey offered me the opportunity Morales says. The UW’s Bothell and for a leadership position addressing this work to happen but don’t always Tacoma campuses, for instance, and know how to make it happen,” he says. diversity at the UW…it offered a tribal colleges and community colleges. way to move closer to having an With the programs described above, immediate impact,” he says. Connecting with communities. By he and his colleagues intend to lead connecting with rural and urban com- the way. Communication, trust, understand- munities, the School can develop more “It’s a large transition, but it’s what’s ing: these make up the basis of a good robust pipelines to connect students to patient-physician relationship. But they needed,” Morales says. “Hopefully, over the health professions where they are time, we’ll make a difference.” can be hard to achieve, especially if a needed. patient and her physician speak a differ- Building the pipeline. In September ent language or have different cultural Learn more » perspectives. Why is this especially 2015, the schools of medicine and dentistry at the UW received a grant Want to join the conversation about important in the 21st century? The diversity and inclusion? Contact totaling nearly $2 million to help U.S. is changing. According to a press mycedi.com. release issued by the U.S. Census in mentor UW undergraduates from June 2015, millennials (born between disadvantaged backgrounds.

16 UW MEDICINE < Top of Mind

AN ANCIENT REMEDY FOR A MEASURABLE MODERN BABIES: HYPOTHERMIA DIFFERENCE IN THE WORLD he concept of using THE POST-BACHELOR FELLOWSHIP AT IHME hypothermia as a medi- Tcal therapy has been ith three bachelor’s around for at least 5,000 degrees — one in years. Its popularity in treat- Wmathematics, ing various conditions has one in genomics and fluctuated throughout his- molecular genetics, and one tory, but, in the last decade, Pediatric neurologist Kevin Joseph, D.O., examines scans in human biology — Marielle it has gained significant of infant brains. Joseph is part Gagnier’s love of quantitative The Institute for Health Metrics and traction in treating babies of the Valley Medical Center research is evident. Translat- team that uses hypothermia Evaluation (IHME) is dedicated to with neonatal encepha- to treat babies with neonatal ing this skill into something understanding — and helping lopathy. Today, whole-body encephalopathy. Photo courtesy useful and tangible was what solve — major global health of Kelley Balcomb-Bartok and Valley problems. And to educating future hypothermia is a standard Medical Center. attracted her to the post- researchers and advocates. Marielle of care in many Level III bachelor fellowship at the Gagnier, pictured above, is finishing can save lives and make the neonatal intensive care Institute for Health Metrics up a fellowship with IHME. difference between a low IQ units (NICUs) — including and Evaluation (IHME) at and a normal IQ.” have a high level of respon- the NICU at Valley Medical the University of sibility,” she says. Classroom Center, a hospital in the When an infant’s brain Washington. That, says time is also important. UW Medicine system. experiences a sudden loss of Gagnier, and “the intensity, “We spend a lot of time It is estimated that blood supply and oxygen, the rigor, and the vast doing statistics and working two to nine out of every neurons begin to die, and opportunity for growth aca- in the nitty-gritty details of 1,000 infants are born with excitotoxic injury results, demically and professionally.” increasing the likelihood this data,” Gagnier says. “But neonatal encephalopathy, a Recent college gradu- of brain damage. “Hypo- our course work is usually disturbance in neurological ates with strong quantita- thermia slows this process broad — more health behav- function caused by oxygen tive skills can apply for a down and gives the brain ior theory and understand- loss. The condition carries a post-bachelor fellowship at the opportunity to heal and ing trends in international high risk of mortality, devel- IHME. They take classes recover,” Joseph explains. It health and development. opmental delays and perma- while pursuing high-level also decreases the severity of That’s been a really good way nent brain injury. However, independent research around seizures, which often occur in to refocus and to remember studies in the last decade core questions: where are the infants with this condition. why we’re doing what we’re have shown that lowering an world’s major health prob- doing — and how we can infant’s core body tempera- Valley’s state-of-the-art lems? How well is society use it.” ture to 33–35 degrees Celsius NICU is complete with video addressing these problems? (or 91.4–95 degrees Fahren- EEG monitoring, a world- How do we best dedicate Generally two years long, heit) — for approximately class team of neonatologists resources to improve post-bachelor fellowships 72 hours within six hours of and nurse practitioners, and population health? can extend into a third year birth — improves a child’s the ability to offer hypother- if fellows elect to complete a Gagnier is addressing life expectancy and mia treatment on site at a master’s degree. As Gagnier these questions by participat- neurocognitive outcomes. moment’s notice. So far, the wraps up her third year, she ing in the Salud Mesoaméri- team has treated two infants has accepted a research posi- “It seems like such a ca 2015 Initiative, designed using hypothermia, and both tion with IHME, continuing simple thing to do to cool to close health inequity gaps. cases went smoothly. her path in quantitative the body down by a few Gagnier is involved at every global health research. degrees,” says Kevin Joseph, “To be able to offer this to level of the project: from D.O., a pediatric neurologist the south King County design, to analysis, to dis- “I’ve come to really love at Valley Medical Center. community is really amazing,” semination of the data. “We the field,” she says. “And it’s amazing that it Joseph says.

FALL 2015 17 Top of Mind >

THE RIGHT THING TO DO: NORTHWEST BIOTRUST

f you’ve had a medical procedure — “We’ve been receiving samples that given a urine sample, had a blood let us study recurring genetic mutations Itest, undergone surgery — you in patients’ tumors, and these samples may have wondered what, ultimately, give us a huge advantage over cell lines happens to any specimens collected. reproduced in the lab,” Méndez says. The answer is that much of that blood, “The ability to study tumors directly urine and post-surgical tissue is makes our discoveries much more discarded. Sometimes, however, these applicable for eventual therapies samples — their use closely regulated and cures.” by the government — are used for Today, Méndez and other U.S. Photo: Clare McLean research. researchers who use specimens — and As any scientist will tell you, these who use patient records, another At present, Northwest BioTrust specimens are supremely important to crucial source of information — are is under development; it’s expected medical investigations. Increasingly, governed by federally mandated to be up and running in the next two medicine is molecular. Researchers are institutional review boards (IRBs). But years. When fully implemented, it will attempting to understand the genetic, the process, while it protects patients streamline the authorization process. protein-based, or metabolic underpin- and their privacy, could be improved. Northwest BioTrust also will be in nings of diseases such as cancer so that That’s what UW Medicine aims to step with — perhaps even exceed, in they can tailor treatments for patients. accomplish with the creation of a terms of rigor — proposed revisions to “This means that, on a practical new program, Northwest BioTrust, IRB rules under consideration by the level, the scientific need for which will partner with Northwest federal government. Finally, Northwest biospecimens and associated health Biospecimen. BioTrust will provide an additional, information has been growing “The IRB determines what samples significant benefit: patients will be able dramatically,” says Stephen C. and records researchers can use. Some- to indicate an interest in participating YOUR CONTRIBUTIONS TO OUR MISSION Schmechel, M.D., Res. ’01, Fel. ’03, times, they require the researcher to in clinical trials when they first enter Fel. ’06, Ph.D. Schmechel, a get patient permission; other research UW Medicine. UW associate professor of pathology, projects don’t require that level of “This ability to be involved in directs Northwest Biospecimen, the consent,” says John T. Slattery, Ph.D., trials — we know it’s a real draw for University-based group tasked with vice dean for research. “With North- some of our patients,” said Slattery. collecting and processing research west BioTrust, we’re going to raise the “We want to make it easier to sign up.” specimens. bar and ask every patient interested in Asked if the new consent system There’s no doubt that these supporting research to sign a consent might result in fewer specimens and materials benefit researchers. Take form when they first enter the records for scientists to use, Slattery UW Medicine otolaryngologist UW Medicine system.” doesn’t hesitate. “Possibly fewer will be Eduardo Méndez, M.D., Res. ’05, who available,” he says. “But we know this researches the genomics of head and is what our patients want, and it’s the neck cancer. Méndez has worked with right thing to do.” Schmechel’s group for three years.

18 UW MEDICINE REPORT TO DONORS 2014–2015 YOUR CONTRIBUTIONS TO OUR MISSION

FALL 2015 19 TEAMWORK Photo: Karen Orders

“People ask me if I will treat them the same way I treat the Seahawks. I say, ‘You’ve got it backwards. I treat the Seahawks the same way I treat you.’” —Stanley Herring, M.D., Res. ’82, UW Medicine TEAM PHYSICIAN, SEATTLE SEAHAWKS

tan Herring has a soft Texas drawl, a sense of humor education and patient care. Some of their stories — a and years of expertise in rehabilitation medicine. It’s new center in palliative care, a major push for Alzheimer’s Snot hard to see why the Seahawks chose him as a research, a scholarship for Montana students, and team physician. And it’s not difficult to understand why others — are featured in the pages that follow. the NFL and the Pigott family chose UW Medicine — Will the Seahawks make it to the Super Bowl this year? where Stan and neurosurgeon Richard Ellenbogen, M.D., A lot of us are hopeful. But will UW Medicine continue to have focused for years on athletes’ well-being — as the move forward, stacking up wins for medicine? The answer place to help found the UW Medicine Sports Health is a resounding “yes”— because of you. Thank you for and Safety Institute. your generosity. The institute is a team effort, one made stronger with investment. In fact, this segment of the magazine is full of good stories about teamwork: donors working with us to make medicine better. In the past fiscal year, more than 16,000 people and organizations gave more than $177 million to UW Medicine’s efforts in research, Don Theophilus CHIEF ADVANCEMENT OFFICER, UW MEDICINE VICE PRESIDENT FOR MEDICAL AFFAIRS, UNIVERSITY OF WASHINGTON

20 UW Medicine REPORT TOTO DONORS DONORS 2014–2015 2014–2015 2014–2015 YEARTHE YEAR AT ATA GLANCEA GLANCE

Who are our donors? What did they contribute?

16,024 individuals and organizations Total: $177,246,538

Corporations 622 (3.9%) Family foundations $11,165,334 Other organizations Foundations 258 (1.6%) (6.3%) UW alumni $64,740,237 4,429 UW alumni (36.5%) Foundations (27.6%) $8,937,234 197 (1.2%) (5.1%)

Family foundations Friends Other $10,631,436 Friends 62 (<1%) organizations (6%) 10,456 $68,245,931 (65.3%) Corporations (38.5%) $13,526,361 (7.6%)

Generous alumni: 2,165 UW Medicine alumni gave The power of planned giving: UW Medicine more than $2 million in gifts and grants over the received more than $5.8 million from donors past fiscal year. who gave through their estates.

What did they support? Strengthening the endowment

Endowment type New in 2014–2015 Total Program support Faculty support $29,058,572 (16.4%) Chairs (for faculty) 3 98 $136,108,096 (76.8%) Professorships (for faculty) 4 71 Student support 17 453 Other/excellence funds $1,549,646 (.9%) Research funds 15 246 Student support Other 3 81 $10,388,675 (5.8%) Many contributors created or augmented endowments, Capital funds invested funds that support UW Medicine’s work in $141,549 (<1%) perpetuity. More than $20.6 million in gifts were directed to the endowment in the last fiscal year.

UW UW Medicine Medicine YOUR YOUR CONTRIBUTIONS CONTRIBUTIONS TO TO OUROUR MISSIONMISSION 2121 The Advocate Alan Frazier, an advisor to J. Randall Curtis and his colleagues, was delighted to hear about the Cambia Health Foundation’s gift. “Palliative care is an area of medi- cine that gets a bit overlooked, despite its importance,” he says. Frazier, in his turn, is making sure palliative care gets its due through a contribution from the Frazier Family Foundation. Curtis is grateful for the support. “With the foundation’s gift, we can help ensure patients receive the care they really want when they fully A RETURN ON HUMANITY understand all their options,” says Curtis. The Cambia Palliative Care Center of Excellence

The Cambia Palliative Care Center of Excellence’s director, J. Randall Curtis, M.D., Res. ’91, Chief Res. ’92, MPH (right), and its co-director, Anthony L. Back, M.D., Res. ’87, Chief Res. ’88. Photo: David Wentworth Photography Photo: David Wentworth

t’s a funny thing to say — that death is a new level in being able to focus across their patients,” says Farber. Appreciating “ a healing — but it is,” says Mark Ganz. UW Medicine,” says J. Randall Curtis, the importance of training, the Farbers IGanz, president and CEO of Cambia M.D., Res. ’91, Chief Res. ’92, MPH, the created a professorship to support Health Solutions, is remembering his center’s director and the A. Bruce palliative care education. father, a family physician who knew his Montgomery, M.D.-American Lung Curtis finds the professorship a fitting patients so well that he could make Association Endowed Chair in Pulmonary tribute — both to the long professional near-intuitive leaps in diagnosis. Ganz and Critical Care Medicine. The founda- partnership shared by Stu and Annalu, accompanied his father on hospital tion’s gift is strengthening the center’s and to Stu Farber personally. “He was rounds. “One of the things that was foun- infrastructure, allowing the hire of new always a passionate educator of medical dational to his practice was the notion faculty and permitting more focus on students, physicians, nurses and others that healing is much more than just the research and educational programs to providing palliative care,” Curtis says. cure of a medical condition,” he says. help inform best practices in clinical care. “That legacy is something we very much Dr. Ganz was an early practitioner Over the next few years, the Cambia want to continue.” of palliative care, the art of listening to PCCE has big plans: in summary, to Education is important to Mark Ganz, and serving patients and families at the make the practice of patient-centered too. His mother needed palliative care at hardest times in their lives: when they’re palliative care the standard throughout the end of her life, but she didn’t receive dying, during medical emergencies, or UW Medicine. It’s a plan that made it; her physicians had not been trained when they’re managing a chronic condi- Stuart J. Farber, M.D. ’74, proud. Before that way. Those memories influence tion. But palliative care doesn’t always he passed away in 2015, Farber served Ganz’s hopes for the Cambia Palliative come naturally to physicians and other as the Cambia PCCE’s director of clinical Care Center of Excellence. care providers, who are pressed for time operations, and he was the founding and trained to do battle with disease. director of the palliative care service at “I’d like to see the Pacific Northwest viewed as a shining center for this trans- Enter the Cambia Palliative Care UW Medical Center. This work, says his formative palliative care model,” says Center of Excellence (Cambia PCCE) at wife, Annalu Farber, “gave him great joy.” Ganz. “We’re confident that with this UW Medicine, which recently received a He also wanted to see this work investment in UW Medicine, there will significant investment from the Cambia broadly applied. be a great return.” Then Ganz pauses, Health Foundation for education and “Stu hoped that, someday, it would considering. “This is all about a return on research. “[The gift] really launches us to be the way all doctors would work with humanity,” he says.

22 UW Medicine REPORT TO DONORS 2014–2015 DREAMING HIGH FOR MONTANA An alumnus gives back to his alma mater

ou could say that Irene Erie got As a result, Erie is very grateful to the Although Erie’s scholarship will take her husband, Norman, into medi- institutions that helped make his dream a little while to get up and running, Pihl Ycal school. It was 1954. They had a reality, and he recently created the is just the type of student he hopes to one small child and another on the way. Irene and Norman Erie, M.D., Endowed support: dedicated to rural areas and to They had $300 to their name. The tim- Scholarship Fund at the UW School service. More generally, he’s using his ing was not auspicious. Even so, Irene of Medicine to support UW medical gift — doubled by the Huckabay Family thought he should try. “The application students from Montana. Challenge Match — to settle a debt of was a prayer,” says Norman Erie, gratitude. M.D. ’58. “I was amazed when I got in.” Caroline Pihl is a third-year medical student; like Erie, she hails from “The way I look at it, it’s payback,” Irene inspired him to apply; then, Montana — in her case, a small town says Erie. “I always felt privileged to have a scholarship from the UW School of called Pray. Like Erie, she’s interested in gone to the UW School of Medicine be- Medicine allowed Erie to attend. “We opening her own family practice in a cause it is such a great medical school.” never would’ve made it without that,” community in need of such services. And, Erie says. like Erie, she’s a scholarship recipient.

Erie grew up in Montana, and his “Scholarships mean the world,” Pihl The state of family didn’t have many resources. He says. “When I think about opening a Montana attended the College of Great Falls (now small primary-care clinic, I think about produces great vistas — and a university) on scholarship, and he how every dollar matters. The less debt generous worked as an x-ray technician. “It was I leave medical school with, the fewer alumni, like too high for me to dream to be a doctor barriers I’ll have to building a Norman Erie, at that time,” he says. community-integrated clinic with M.D. ’58, who meaningful programs for my patients.” created a scholarship for Montana students.

UW Medicine YOUR CONTRIBUTIONS TO OUR MISSION 23 SPORTS AS MEDICINE Helping Our Athletes

Jim Pigott, center, and Stanley Herring, M.D., Res. ’82, left, visit with VICIS CEO Dave Marver at a lab in the UW Department of Mechanical Engineering. VICIS, a UW spinoff, is working on creating a safer football helmet; Pigott and his wife, Gaye, are supporting concussion research. Photo: David Wentworth Photography Photo: David Wentworth

eam loyalty starts young. “From nation. In his turn, he praises the National But to say the institute was created quite an early age, probably 9 or Football League. “Without the NFL, we solely to focus on concussion preven- T10, I started going out with my would not have been successful in getting tion, or even on sports safety, is to miss parents to football games,” says Lystedt Laws in all 50 states and D.C.,” a larger theme. That larger theme is that UW Medicine advocate Jim Pigott. says Herring. “They were a very helpful sports are positive — that, in fact, sports His affection for the UW Huskies and partner in our legislative efforts.” are a kind of medicine. “Yes, we have the University of Washington — despite The NFL, in fact, has done even more; an opportunity to make sports safer… earning a degree from rival Stanford — still their gift provided the foundational but the benefits of exercise have been runs strong. In fact, Pigott and his wife, support to help create the UW Medicine expounded upon in articles for 40 or 50 Gaye, are pledging a gift that will help Sports Health and Safety Institute. The years,” says Richard G. Ellenbogen, M.D., athletes of all ages and stripes at the new institute will increase UW Medicine’s chair of the Department of Neurological UW Medicine Sports Health and Safety capacity to conduct research around Surgery. Exercise lowers levels of obesity Institute at Harborview Medical Center. sports health and safety, to advocate, and the incidence of cardiac disease, and to educate the medical community, stroke and diabetes, all of which are The institute was inspired, in part, major health problems. by another sports enthusiast: Zackery the sports community and the public. Lystedt. In 2006, the 13-year-old “Education is an important part of For now, concussion is the institute’s sustained a devastating traumatic brain growing a culture of safety for athletes priority. Eventually, with sufficient fund- injury (TBI) — preventable, had his of all ages and in all sports,” says Jeff ing, it will take on other issues: prevent- concussion been managed correctly — Miller, NFL senior vice president of health ing sudden cardiac arrest; promoting during a football game. Afterward, he and safety policy. “We are tremendously exercise for people with physical or and his family became staunch advocates supportive of UW Medicine’s work and intellectual challenges; investigating for laws, now passed throughout the look forward to supporting their efforts to nutrition and hydration; addressing nation, that regulate athletes’ return to advance sports safety.” athletes’ mental health. play after concussion. Like the NFL, the Pigotts are address- The ultimate message of the institute Stanley A. Herring, M.D., Res. ’82, ing concussion: their gift will enable the and its faculty, however, is this: everyone medical director of the new institute and recruitment of a neuroscientist to conduct is an athlete, and we all deserve the the Zackery Lystedt Sports Concussion research and coordinate the 20-plus TBI benefits of exercise. The research, the Endowed Professor, was a key player in researchers already in place at the education and the advocacy are all passing the Lystedt Law in Washington University of Washington. directed to promoting that message. state. It was the first law of its kind in the “It will be our gift to the next generation,” says Herring. 24 UW Medicine REPORT TO DONORS 2014–2015 FEELING LIGHT YEARS YOUNGER A heart procedure turns back the clock

Bob Eveleigh (left) and his friend Ruben Gunst (right) both received a transcatheter valve replacement at UW Medical Center; they were encouraged to do so by their friend, Yvonne Manssom (center), a retired physical therapist from Seattle Children’s. Photo: David Wentworth Photography Photo: David Wentworth

ob Eveleigh, a retired Navy veteran, Historically, the only effective treat- Eveleigh is living proof of TAVR’s leads an active life. He golfs. ment for aortic stenosis is open-heart effectiveness. “I was active right away, BHe enjoys ballroom dancing. surgery, which still remains the best within a month after the procedure,” So when his heart was compromised option for some patients. But for those says Eveleigh. “I’ve gotten more active by aortic stenosis, his quality of life was with other medical conditions or as time has gone on.” And in gratitude compromised. In fact, his life was at risk. advanced age, it can be too risky, leaving for a good outcome, Eveleigh made a them with few options. contribution to the UW Medical Center When people get older, the aortic Fund for Greatest Need. “I benefited a valve can narrow to the point where Now, however, patients like Eveleigh great deal from having the procedure,” blood can’t get through. “It’s a highly have the option of a minimally invasive says Eveleigh. fatal condition,” says James M. procedure called TAVR — a transcatheter McCabe, M.D., UW assistant professor aortic valve replacement. UW Medicine McCabe understands Eveleigh’s of medicine in the Division of was instrumental in the procedure’s de- impetus for making the contribution — Cardiology. McCabe, director of the velopment, participating in groundbreak- many TAVR patients are enormously Cardiology Catheterization Lab at ing valve trials and driving improvements. grateful for their care. UW Medical Center, is Eveleigh’s doctor. “TAVR is far and away one of the most “The five-year prognosis for people with successful and important new medical “They feel like they’ve recaptured the aortic stenosis is worse than for people technologies in the last 50 years,” says life that may have slipped through their with widely metastatic cancer.” McCabe. fingers over the preceding years,” says McCabe. “That is a tremendous gift.”

UW Medicine YOUR CONTRIBUTIONS TO OUR MISSION 25 Tom Ellison, center, and his wife, Sue, invested in Alzheimer’s FINDING THE SILVER BULLETS research at UW Medicine. The Precision medicine and Alzheimer’s disease expertise of two leading faculty, Tom Montine, M.D., Ph.D. (left), and Tom Grabowski, M.D. (right), will be key to research progress. Photo: Clare McLean

hy invest in a cure for The project has three essential steps: The Ellisons aren’t expecting to find Alzheimer’s disease? “It’s a assessment, surveillance and treatment. a single silver bullet to cure Alzheimer’s Wlong, unfolding story,” says The first involves assessing a person’s disease; rather, they hope to find many. Tom Ellison. “It starts with many family genetic risk when they visit their physi- That’s because Tom Montine’s work is members who were affected by the cian. The second is creating noninvasive, based around the idea that there will disease.” low-cost surveillance tools capable of be multiple treatments for Alzheimer’s, detecting the earliest beginnings of depending on what kind of Alzheimer’s Ellison and his wife, Sue, looked at a Alzheimer’s disease. The third is devel- disease a patient has. The Ellisons have number of programs across the country oping a host of therapeutics tailored to high hopes that their gift will help the to see where a research investment could thwart the patient’s molecular drivers of five million-plus people in the U.S. who make the greatest difference. They soon Alzheimer’s. have the disease and the millions more realized they didn’t have to look far. “We around the world who are at risk. decided we’d have the greatest impact Montine has no doubt the Ellisons investing in our own backyard with picked the right place to invest. “The And that’s not all. With their gift, the UW Medicine,” Ellison says. fact that we have federal funding for an Ellisons want to inspire others to join Alzheimer’s research center makes them in investing. Part of that decision was determined UW Medicine a particularly powerful by their trust in and respect for Thomas place to do this research,” he says. “If you look at your circle of family J. Montine, M.D., Ph.D., chair of the He greatly appreciates the Ellisons’ and friends, you’ll find a person with Department of Pathology. Montine, who support. dementia, or someone taking care of a is also director of the UW Alzheimer’s person with dementia,” Ellison says. Disease Research Center and the Nancy “We’re extremely grateful for the “We want other contributors to help and Buster Alvord Endowed Chair in research funding we have from the UW Medicine take steps now to help all Neuropathology, has launched a project National Institutes of Health, but it’s of us a few years down the line.” to find cures for Alzheimer’s disease limited,” Montine says. “The Ellisons’ using precision medicine — treatment very generous gift is foundational to that is personalized to each individual. what we’re able to achieve.”

26 UW Medicine REPORT TO DONORS 2014–2015 LISTEN AND LEARN The Henigson Chair

Patient Sonja Staley chats with her physician, Michael Linenberger, M.D., Fel. ’89, before beginning a drug infusion at Seattle Cancer Care Alliance. They’ve known each other for 14 years, and Linenberger says Staley is doing well. “Hopefully, your lymphoma will never come back to haunt you,” he says. Photo: David Wentworth Photography Photo: David Wentworth

obert Henigson was a Harvard- “There was never a feeling that you had In 2011, Phyllis and Robert decided trained trial lawyer. Phyllis Henig- just 10 or 15 minutes with him, and then to create a professorship to recognize Rson was a stewardess with United you had to leave,” she says. Dr. Linenbergers’s superb service and to Airlines, a legal secretary and a court support the Division of Hematology’s reporter. They met at his office in Los “I didn’t do anything magical,” says work in teaching and research. That’s Angeles, married in 1966 and proceeded Linenberger. But he really listened. exactly what the professorship, recently to spend the rest of their lives together: In addition to wanting to feel better, upgraded to a chair, is doing. With the skiing and backpacking, raising their two Mr. Henigson wanted fewer transfusions. professorship’s help, Linenberger, the children, Ted and Jeff, and, ultimately, So Linenberger tried a treatment regimen program director for the hematology- retiring to Orcas Island. not often used: fewer transfusions and oncology fellowship at UW Medicine, is gentle doses of a medication that had creating a new curriculum for fellows, Mr. Henigson acquired a slow-acting a 50-50 chance of working. “Happily, based partially on the values of palliative bone-marrow cancer called polycythe- Bob responded tremendously well,” says care. A recent training program he and mia vera around age 60. By the time he Linenberger. his colleagues developed emphasizes was in his early eighties, the disease had the power of the patient story, com- In listening, Linenberger personifies a become unbearable. He was exhausted munication skills, work-life balance for positive trend in medicine, one strongly and frail and had grown weary of blood physicians, and focus on the patients’ emphasized in the practice of palliative transfusions, a standard part of treat- and families’ spiritual practice. “Classic care. “It formalizes what many of us ment. Then he met Michael Linenberger, Michael,” says Jeff Henigson. M.D., Fel. ’89, now the holder of the have learned the hard way about becom- Robert and Phyllis Henigson Endowed ing a good doctor and a good person,” Robert Henigson died in 2014 of Chair in Hematology. says Linenberger. Listening. Spending heart failure, but his legacy lives on — as time. The Henigsons noticed. does the family’s steady affection and “Dr. Linenberger was very different regard for Michael Linenberger. “We saw “When my father was nearing the from the doctors Dad had seen before,” a genuineness in Michael,” Phyllis says. end of his life,” says Ted Henigson, “I says Jeff Henigson. “He has this totally “Our family feels that it was an honor remember feeling very appreciative of holistic approach toward health care.” and a real privilege to work with him.” Phyllis Henigson, Jeff and Ted’s mother, Dr. Linenberger’s presence and care in remembers Linenberger’s patience. laying out the road ahead.”

UW Medicine YOUR CONTRIBUTIONS TO OUR MISSION 27 OUR CORPORATE PARTNERS

In the listing below, we recognize UW Medicine’s Nortis, Inc. Merial, Inc. Theravance Biopharm Northwestern Mutual Investment Corporate Partners in fiscal year 2014–15, leaders Services Supporting Partner Perkins Coie LLP in enterprise, biomedical innovation, research and ($25,000 to $49,999) Point B development — and strategic collaborators in AbbVie Inc. Proliance Orthopedic Associates Boston Scientific supporting patient care, research and education. Seattle Mariners First Choice Health Skechers USA, Inc. Thank you for your partnership. GeffenMesher Stryker Corporation W. L. Gore and Associates Inc. SUMIT Insurance Strategic Partner Samsung Semiconductors Inc. The JK Group Inc. True North Therapeutic ($100,000 and more) Sangamo Biosciences Inc. Laurel Creek Manor LLC UCB Pharma, Inc. Agilent Technologies Solid Ventures Microsoft Corporation Wells Fargo Foundation Alcon Research Ltd. TEVA Pharmaceutical Industries Ltd. Mitokinin, LLC Amgen VentiRx Pharmaceuticals, Inc. Nelson Blair Langer Engle PLLC Friend AO Spine North America Waters Corporation PET/X LLC ($5,000 to $9,999) Cambia Health Foundation Westat Inc. Summit Surgical Corporation Bayer HealthCare Costco Wholesale Corporation Western Washington Toyota Pharmaceuticals Partner GlaxoSmithKline Biologicals Dealers Association Capital Guardian Trust Company ($10,000 to $24,999) IGM Biosciences, Inc. Liberty Subaru Major Partner Acumed Janssen Research & Development Mobisante, Inc. ($50,000 to $99,999) AEG Live Medtronic Motors Northwest American Medical Systems Inc. Arthrex Inc. NASPA Performance Staffing Bruker Daltonik GmbH AstraZeneca International National Football League Revalesio Dual Therapeutics LLC The Boeing Company Nestlé Health Science Rock Solid Restaurants LLC FUJIFILM SonoSite Inc. Calimmune Inc. Oncosec Medical Incorporated The Tulalip Tribes glassybaby LLC DePuy Synthes PAI Life Sciences, Inc. Tongkang International Health Google Inc. Epic Prosetta Biosciences Inc. Consultants Intuitive Surgical, Inc. Gilead Sciences Inc. Quantum Energy Company Ltd. UniSea, Inc. Mallinckrodt Inc. Harper Engineering Company Roche Holding AG United Luv Muckleshoot Indian Tribe Liberty Mutual Foundation The Safeway Foundation Merck and Company Inc.

The Turner Society Named after Edward L. Turner, M.D., the dedicated and visionary founding dean of the UW School of Medicine, the Turner Society is a group of contributors whose generous annual gifts to UW Medicine are essential to our work in research, education and patient care.

Every year, hundreds of Turner Society members join UW Medicine in our mission: improving the health of the public. In recognition of your contributions, we invite you to visit the special pages, created for Turner Society members, on our website: supportuwmedicine.org/the-turner-society. Learn about the benefits of membership, and watch the videos — prepared for our Turner contributors and shown at our 2015 Tomorrow Today event — presented by some of UW Medicine’s leading faculty.

Thank you for your generosity and commitment.

TURNER SOCIETY

28 UW Medicine REPORT TO DONORS 2014–2015 < MEDEX Northwest . Making It Happen Jeff Stubblefield, PA-C (Anchorage Class 2)

MEDEX Northwest has a proud the Air Force as an independent-duty history of serving veterans, and medical officer. He rotated through dif- today, more than 30 percent of ferent specialties, including emergency, MEDEX’s students come from the dental, surgery, family practice and ranks of Army medics, Navy corps- aerospace medicine, practicing with men or Air Force independent-duty the guidance of a physician in remote medical officers. That group includes locations and traveling to Vietnam, Jeff Stubblefield, PA-C (Anchorage Cambodia, Laos and New Guinea, not Class 2), a first assist in neurological to mention sites in the U.S. “I’ve hit surgery at the Alaskan Native just about every piece of dirt in the Medical Center in Anchorage, world,” says Stubblefield. Alaska. After retiring from the military Stubblefield was surprised when in 2009, Stubblefield and his family the center recruited him to do moved to Alaska, and he began neurological surgery. “I’d been in looking into MEDEX Northwest. some operating rooms where there He distinctly remembers the warm Jeff Stubblefield, PA-C, spent a long time traveling and working around was some brain surgery done,” says welcome faculty gave to veterans the world — good preparation for Stubblefield, “but I was never trained at information sessions. He entered practicing medicine in Alaska. in it.” Ash Marquardt, PA-C (Seattle the program in 2010 and graduated Class 33), the Anchorage site director in 2012. “At MEDEX, it felt like I for MEDEX Northwest, explains. was transitioning from active duty to he explains. “The patient needs “We recommended him,” he says. reserve status,” Stubblefield says. something, you do what you have “It’s true; he didn’t exit MEDEX Now an employee of the Alaska to do to make it happen.” Even if as a neurological surgical assist PA,” Native Tribal Health Consortium you have bad news, or can’t do what continues Marquardt. “But Jeff has (ANTHC), which provides health they need, just be honest, he says; the tenacity to study what he needs services to 130,000 Alaska Natives and you’ll get a pretty good reception. to know. I’m sure he went into the Native Americans, Stubblefield is clear “It’s not brain surgery,” job, got an idea of what was expected about some of the challenges. Weather, Stubblefield says. of him, went home for probably three for one, which can prevent patients or four months and just hit the books from traveling. A lack of specialists, for every night after work until he was another. By the time Stubblefield sees Full story at uwmedmagazine.org » tuned up. That’s the kind of guy some patients at the center’s neurosur- he is.” gery clinic, they’ve traveled a long road Stubblefield was definitely used for relief of their symptoms. to hard work. Before he entered the Given the challenges of patient PA training program at MEDEX care in Alaska, Stubblefield has Northwest, he’d spent 21 years in developed his own guiding principles. “I’ve always been task-oriented,”

FALL 2015 29

Alumni and Student Updates >

THE 2015 ALUMNI AWARDS Respected by their peers as innova- tors, leaders, researchers, teachers and compassionate physicians, this year’s recipients of the UW School of Medicine Alumni Awards were recognized at A Toast to the UW School of Medicine during Reunion Weekend in June. Video tributes are posted online at uwmedmagazine.org. Photo: Team Photogenic Photo: Team 2015 Distinguished Alumni From left to right: John Betz, PA-C, John Olerud, M.D., Sue Verreault, Psy.D., who accepted Award: John Olerud, M.D. ’71, the award on behalf of her late partner, Jamie Garcia, M.D., and Jared Baeten, Ph.D., M.D. Res. ’76, Res. ’78 Dr. Olerud, professor emeritus and former head of the Division of Alumni Service Award: Nominate Exceptional Alumni! Dermatology, was honored for his John Betz, PA-C (Seattle Class 1) We encourage your nominations contributions to the field of Mr. Betz was recognized for his for the 2016 UW School of Medicine dermatology, where he is universally 44-year career serving the rural com- Alumni Awards. Anyone who has admired as a physician, teacher and munity of Othello, Wash. Beginning in received a degree from — or com- researcher. He has published more 1970, he cared for several generations pleted residency or fellowship training than 100 articles, with much of his of Othello residents, including many in — a program administered by the research focused on the areas of wound farmworkers — often for no charge. UW School of Medicine is eligible. healing and T-cell lymphoma. Nominations are due by Friday, Jan. We also congratulate the Alumni Humanitarian Award: 15, 2016. Read more and nominate at following alumni, honored by uwmedalumni.org/awards. Jamie Garcia, M.D. ’99 MEDEX Northwest in April. (awarded posthumously) Dr. Garcia was honored for years Lifetime Achievement Award dedicated to bringing healthcare to June Betsch, PA-C (Seattle Class 20). the most impoverished members of her PA Pioneer Award community in California, providing John Betz, PA-C (Seattle Class 1), care to the homeless and improving Paul Snyder, PA-C (Seattle Class 1), and Our “Top Docs” Richard Bunch, M.D. access to healthcare for the uninsured. An impressive number of Outstanding Preceptor Award UW School of Medicine alumni Alumni Early Achievement Carlos Vigil, PA-C (Seattle Class 28) and and faculty were recognized as Award: Jared Baeten, Ph.D. ’01, Martin Buccieri (Seattle Class 31). “Top Doctors” by both Seattle M.D. ’03, Fel. ’08 Future of MEDEX Award Magazine and Seattle Met Dr. Baeten was recognized for his Laura Katers, PA-C (Seattle Class 45). magazine. Our congratulations exceptional achievements in global MEDEX Excellence in to all of them! See lists of health, his excellence in teaching, and Teaching Award honored alumni and faculty his contributions to research, which Patrick Parenzin, PA-C (Seattle Class 39). at uwmedmagazine.org. have had a major impact on global MEDEX Humanitarian Service Award HIV prevention and reproductive William Bomberger, PA-C (Yakima Class 8). health priorities.

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Anchorage, Alaska. Barb Doty, M.D. ’82, The Gift of a Steven Floerchinger, M.D. ’87 Stethoscope Boise, Idaho. Mary Barinaga, M.D. ’95, In ceremonies across the WWAMI Res. ’98, Anne Eacker, M.D. ’97, region, each of the 245 students in Chief Res. ’01 this year’s entering class received their Bozeman, Mont. Meghan Johnston, first stethoscopes, a gift from the M.D. ’11, Leslee Kane, M.D. ’07, Christy UW School of Medicine Alumni Mitchell, M.D. ’98 Association. Alumni volunteers from 20 classes, ranging from 1954 to 2011, Laramie, Wyo. Jasper Chen, M.D. ’07, presented the stethoscopes. Thor Hallingbye, M.D. ’08, Mark McKenna, M.D. ’05, Samantha Michelena, M.D. ’11, In Seattle, Scott Stuart, M.D. ’01, Greg Wallace, M.D. ’09 Res. ’04, Chief Res. ’05, the new president of the association, spoke Seattle, Wash. Angela Chien, M.D. ’95, Alison Dragnich Hartvigson, M.D. ’06, about the support alumni can provide Photo: Clare McLean Res. ’09, Margaret Isaac, M.D. ’03, Henry students through programs like SAID Spokane students wear their new and HOST, as well as the symbolic and stethoscopes from the alumni association. Kuharic, M.D. ’54, Michelle Oh, M.D. ’94, practical role of the stethoscope. “Even Scott Stuart, M.D. ’01, Res. ’04, Chief more important than hearing a wheeze Res. ’05, Julie Vath, M.D. ’00, Ray Vath, Our Alumni Volunteers or a murmur, using this stethoscope M.D. ’65, Res. ’69, Carl Wigren, M.D. ’01, Thanks to the alumni, listed at right, will allow you to lay healing hands on Res. ’05 who participated in stethoscope your patient,” he said. “The magic in ceremonies across WWAMI. If you’re Spokane, Wash. Karlene Arguinchona, your healing hands is comfort, care, interested in participating in the future, M.D. ’85, David Bare, M.D. ’75, Jerico empathy and reassurance.” please contact the alumni relations Cairns, M.D. ’07, David Greeley, M.D. ’89, Congratulations to the office at [email protected]. Warren Toews, M.D. ’71 newest students at the UW School of Medicine!

UW Night at the Mariners While the Seattle Mariners weren’t triumphant on July 10, 2015, our alumni still enjoyed a UW School of Medicine Alumni Association-hosted gathering at UW Night at the Mariners. Joining more than 1,000 University of Washington alumni and community members, our alumni, students, family and friends came together at Lookout Landing inside Safeco Field, where they mingled, reconnected, enjoyed a dinner of baseball-field favorites and watched the Mariners take on the L.A. Angels. Photo: Lynne Salkin Morris Photo: Lynne Fourth-year students Kramer Wahlberg, Beth Stroeher, Tom Wright and Josephine Garcia join the fun at the Mariners game.

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Alumni and Student Updates >

UW School of Medicine 2015 Reunion Weekend “It was absolutely fantastic to get at UW Medicine and beyond, and a together with old buddies and find out tour of Harborview Medical Center. what in the world they had been doing The weekend concluded with class for the last half-century.” dinners at restaurants across the city. – Dick Baerg, M.D. ’65 Thank you for making Reunion Week- end 2015 one for the record books! On June 5 and 6, more than 550 And now for 2016: save the date! alumni and their guests reconnected If you graduated in a year ending in a Alumni and friends gather at A Toast to the at the UW School of Medicine 2015 UW School of Medicine at the Museum of 1 or a 6 (such as 1961 or 1996), save History & Industry on Friday night. Reunion Weekend. The two-day the date for next year’s reunion: program began with a WWAMI- Friday, June 3, and Saturday, June 4! themed reception for all graduates at Visit uwmedalumni.org/reunion for more the Museum of History & Industry. information, and consider joining your The following day, participants gathered class reunion outreach committee — for a variety of programs, including an it’s fun, and the time commitment is update on the School, presented minimal. To volunteer, contact by Dean Paul G. Ramsey, M.D.,

[email protected] or 206.685.1875. Photogenic Photos: Team “Doc Talks,” highlighting innovations Monika Mahal, M.D. ’95, Susan Kim, M.D. ’95, Res. ’96, and Martin Makela, M.D. ’95, enjoy their reunion.

“Thank you for all the effort you “[My HOSTs were] really lovely Students Say put into HOST! I was matched seven people! It was great to get their times, which was not only a significant perspectives on the town they live in “Thanks!” financial help, but also such a pleasant and the program they are training in.” More than 250 alumni help our introduction to new cities!” Alice Bremner, M.D. ’15 students and their school each year: assisting with mock interviews, Tiana Nizamic, M.D. ’15 hosting students who are traveling to For more information about “I had a great time at my SAID interviews for residencies, or sharing how to get involved, please visit advice. Our students greatly appreciate event! The doctor who hosted me has uwmedalumni.org/volunteer. you. At right are a few words of thanks since been sending me articles that he we’ve received from students in recent finds relevant to our conversation. months. Very thoughtful and helpful!” Ramsey Larson, E-2012

32 UW MEDICINE

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Speed “Dating” and Physical Therapy “Everyone was really positive, the atmosphere was great, and I feel like I walked away with great information as well as future contacts.” That was Catey Whitlock’s assessment of a career networking event for physical therapy students, one hosted by the alumni association and the Department of Rehabilitation Medicine in May. During the fun, three-hour program — structured to resemble a speed-dating event — students could speak with 20 alumni, who were seated at tables divided by specialty and work setting. Students changed tables every 10 minutes, which allowed them to learn about a variety of careers. Afterwards, while chatting over appetizers, students were able to ask more detailed questions. “I had the most amazing time with my classmates and the UW alumni,” says Whitlock. To participate in the next event this spring, Students speak with alumni about careers in physical therapy. please contact the alumni office at [email protected]. Photo: Lynne Salkin Morris

EMERGENCY MEDICINE’S FIRST RESIDENTS

Four years at local urban hospitals, rotations at rural and international sites, and now: the end of residency. The inaugural class of the UW Medicine Emergency Medicine Residency Program, consisting of five students, completed their training on Friday, June 12, 2015. Four are staying in the area to pursue further training. “The UW emergency medicine residency is the only civilian emergency medicine training program in the WWAMI region and, as such, addresses an important aspect of UW Medicine’s mission to improve the health of the public,” says Susan Stern, M.D., UW professor and head of the Division of Emergency Medicine. The division also graduated its first medical education research fellow, Joshua Jauregui, M.D., Fel. ’15.

Our first class of emergency medicine residents: Alisha Brown, M.D., Res. ’15, Rebekah Heckmann, M.D., Res. ’15, Patrick Maher, M.D., Res. ’15, Blaise Bellows, M.D. ’11, Res. ’15, and Ryan Gould, M.D., Res. ’15. Photo courtesy of the program.

FALL 2015 33 Seen & Heard >

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  34 UW MEDICINE < Seen & Heard

In this segment, we document some special moments at UW Medicine.  Graduates of the 2015 Innovations in Pain Research Summer Program, supported by  a multi-year gift from the Scan I Design Foundation. Top row: Logan Condon, Dylan Moore and Tom Gebert. Bottom row: Qimin Liu, Alta Steward, Albert Ng and Juan Espinosa.  Medical student Maya Newman and her husband, Ben Mahdavi, welcomed their son, Elan David Mahdavi, this year.  Nearly 200 guests gathered at Seattle Art Museum on May 26, 2015, for the Dean’s Circle Celebration, an event that  recognizes UW Medicine’s contributors. Pictured: Julie Nordstrom, vice chair of the UW Medicine Board.  Mimi Gardner Gates and William H. Gates, Sr., upon receiving the 2015 Brotman Leadership Award, at Dean’s Circle.  J. Randall Curtis, M.D., Res. ’91, Chief Res. ’92, MPH, director of the Cambia  Palliative Care Center of Excellence, and his daughter, Alice, at Dean’s Circle.  Tomorrow Today, another annual donor event, featured faculty giving talks at the EMP Museum on Sept. 28, 2015. The event was emceed by Molly Shen of KOMO 4 News.  Vision expert Russell Van Gelder, M.D., Ph.D., one of Tomorrow Today’s presenters.  Alan and Jean Kahn hosted a celebration for Montana WWAMI alumni, students, residents and faculty in May 2015. Pictured are students McHale Anderson, Hanna Dysinger, Elizabeth Schiedermayer  and Brook Murphy. 11 13 12  At the MEDEX/Washington Academy of Physician Assistants reception held in April 2015, Terry Scott, MPA, PA-C (Seattle Class 25), shares a laugh with Lynda Storm, PA-C (Seattle Class 35).  A celebration of the Alexander Clowes, M.D. Endowed Chair in Vascular Surgery, created by the Clowes Fund, Inc., in May 2015. The chair honors Dr. Clowes, seated, whose obituary is on page 50. 11 13 In12 September, advocate Chris Carr and his wife, Jackie, held a gathering for friends — and Institute for Prostate Cancer Research faculty — about prostate cancer in the African American community. Pictured: Peter Nelson, M.D., Fel. ’96, Daniel Lin, M.D., Res. ’96, ’99, Chief Res. ’00, Chris Carr, Jackie Carr and Paul Lange, M.D., FACS.

Photos: Event Photos Northwest (6, 7), David Ryder (1), Martin Teintze, Ph.D. (8), Colin Ware (11), James Wehmeyer (9), David Wentworth PhotographyFALL (3, 2015 4, 5). 35 ClassNotes > An astronaut. Our everyday heroes. And hope. ClassNotes

ORGANIZED BY DEGREE. Search for friends by degree, then by the year they completed SURVIVORS their program. CELEBRATION HOW ABOUT YOU? Your classmates would love to hear from you! Send a quick note to BREAKFAST [email protected] or use the online form at uwmedmagazine.org. ClassNotes may be edited for length and content. Photos are very welcome.

Join astronaut, prostate cancer survivor and keynote Major General William “Bill” Corrections Hugh Wang, M.D., writes, “Since 2008, I’ve been a security guard at From Roger Bulger, M.D., Res. ’62, Anders — and hundreds of everyday Sunvalley Shopping Center in Concord, Chief Res. ’65, Fel. ’66. We mistakenly heroes — to support vital research into Calif., and by default, the medical direc- noted Dr. Bulger as deceased in the last tor. I’m probably the oldest active secu- prostate cancer. issue, an error we deeply regret. We’re rity guard, at age 80, in one of the oldest happy to report that Dr. Bulger is very malls in America, housing 170 stores and much alive, and he provided an update Wednesday, December 2, 2015 restaurants under one roof. I am retiring on page 38. 7:30–9 a.m. in 2015, as my physician and I agree that Sheraton Seattle Hotel this is old enough for anyone to work in From Alan L. W. Gunsul, a hand-to-hand combat capacity.” M.D. ’55. We reported that Dr. Gunsul This is going to be the best had a granddaughter attending 1962 breakfast yet! Washington State University, an error we are pleased to correct. Both of his Frank I. Backus, M.D., Res. ’68 granddaughters are registered nurses; (psychiatry and behavioral sciences), his great-granddaughter is at WSU. writes, “I’m keeping involved with our grandchildren in Oregon, where we Steve Fleischmann, Founder and Chair spend summers in Bend. I am enjoying Prostate Cancer Survivors Celebration Breakfast 1955 bridge, slowly learning Spanish, and Dennis Carlson, M.D., writes, “Our continuing to be involved with the reha- Tickets: $250 family and friends are celebrating the bilitation of Thornton Creek in Seattle/ Shoreline. I’m concerned about the Table for 10: $2,500 10th anniversary of an agricultural extension program at the University of earth, excess carbon use, and the unfair- celebrationbreakfast.org Gondar in northern Ethiopia, where I was ness of the current tax structure/military- 206.543.7873 • [email protected] dean of the college of public health in industrial-governmental complex.” the 1960s. As of 2015, we have trained 37,000 elementary school students in 39 1963 schools in the basic skills of maintaining Lon R. White, M.D., Res.’69 vegetable gardens and have provided (pediatrics), MPH, was the chief of the sets of seeds to all of them. Our top epidemiology office, National Institute of priority is improving the intake of Aging, and designed, established, and micronutrients, particularly vitamin A directed the Honolulu-Asia Aging Study. for mothers and children.” He continues to research the epidemiol- ogy and neuropathology of brain aging, 1961 dementia, and Parkinson’s disease. He Save the date for your 55th reunion: holds positions at the Pacific Health Friday, June 3–Saturday, June 4, 2016! Research and Education Institute, the John A. Burns School of Medicine and the UW School of Medicine. He notes that his interests include “taking care of

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livestock (three cats), thinking about kids, bad burn wounds — the result of a car 1974 sitting, thinking, analyzing buckets of crash sustained while chasing a drunk James Mhyre, M.S. ’71 data, thinking some more and writing.” driver. Mike survived, and he went on (biological structure), M.D., writes, to speak at more than 4,000 venues “After retiring from a career in general over the next 32 years. Profits from the surgery, I took up woodworking as an 1964 book, which can be found online, will be avocation. One of my projects was a donated to charity. 24-foot-long (the length of my garage), Allen Wyler, M.D., Res. ’75 two-foot-in-diameter sculpture of DNA. (neurological surgery), writes, “My It is made of various woods and includes new book, Cutter’s Trial, is now out in 31 nucleotide pairs. It took 600 hours to Kindle format, and the paperback was make. After donating it to the Depart- made available May 7th of this year. This ment of Genome Sciences, it was installed one has a legal twist to it!” in the William H. Foege Building on the UW campus.” (See photo on next page.)

J. Donald Easton, M.D., writes, A Half-century With “Subsequent to retiring in 2010 after Harborview 25 years as the chair of neurology at Neil Duncanson, M.D. Brown University, I took up a position as professor of neurology at the University A good listener. That’s a quality of California, San Francisco. I planned that came in handy for alumnus to work 15-percent-time teaching and Neil Duncanson, M.D., Res. ’61 otherwise watch the grapes grow here (pediatrics), FAAP, who spent much at our home in Sonoma. However, one of his career treating children — and thing led to another, and I am now work- much of it teaching medical students. ing full-time as the principal investigator for a large NIH-sponsored clinical trial Duncanson is a graduate of the aimed at preventing stroke in patients University of Washington, and while with transient ischemic attacks. I am he left Seattle to attend the Feinberg having great fun and still have time to play here in the wine country and do School of Medicine at Northwestern University in Chicago, Harborview things with my wife, kids and eight Medical Center, Seattle Children’s and UW Medicine drew him back for grandchildren (one of whom we saw a residency in pediatrics. “Harborview was an intern’s hospital in the sense perform at Carnegie Hall in New York that we interns were the primary doctors,” says Duncanson. “We made last month)! I feel blessed every day when admissions, and we diagnosed and treated patients. Residents and I wake up with the grass below me.” attending physicians were the consultants. Harborview’s rotating intern- 1969 ship was highly sought-after.” He left again — for a stint in the U.S. Army Medical Corps — but he came back to UW Medicine as the assistant director of the birth defects program in 1963 and as an attending physician at Harborview. Even after going into private practice in Burien in 1968, Duncanson maintained a connection with Harborview as a preceptor at the pediatric outpatient clinic. He enjoyed emphasizing some of the more practical aspects of being a pediatrician, from how to hold an infant during a physical exam to how to gauge a baby’s developmental age with a tongue depressor. Ward Buckingham, M.D., right, with his Still, he learned as much from his students as they did from him. younger brother, Mike. “Teaching made me keep up,” says Duncanson. “When you teach or Ward Buckingham, M.D., precept, you have to be up to date and stay on your toes.” Now planning Res. ’74 (internal medicine), Chief to retire, Duncanson will spend more time with his family. But the nearly Res. ’75 (internal medicine), has writ- ten Triumph Born of Ashes: Trooper Mike six-decade relationship with Harborview was something special. “It’s been Buckingham’s Story. The book is about a great ride, and I’ve enjoyed it all,” he says. Ward’s late brother Mike, and it details his seven-month stay at Harborview for

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ICU.) I was elected for three terms, the longest on record. I then served as presi- A Basic Human Right dent of our county medical society and Roger Bulger, M.D. as president of Physicians Medical Group of Santa Cruz, our local IPA. I have been Roger Bulger, M.D., Res. ’62, on the board of the hospital for 15 years, Chief Res. ’65 (internal medicine), serving as president for two. I have retire- Fel. ’66 (laboratory microbiology), ment on the horizon, but I would like believes in health access and equity. to see my current medical group, Santa He credits that belief to his Cruz Medical Group, get going. I was the sole incorporator a few years ago, residency, spent at UW Medical but we have now grown to 58 providers. Center, Harborview Medical Center We have been recruiting, but there is so and the VA. “I learned about the much competition out there. We started world, and I came to believe that out with a primary-care focus, but have effective medical care is a basic slowly become more multispecialty, since human right,” Bulger says. independent specialists are struggling to survive. We are in negotiation with Early in his career, Bulger became an assistant dean at the UW School of our local five-physician pulmonary group Medicine — upon the invitation of Dean John R. Hogness, M.D. Hogness and eight-physician radiology group. wanted to make UW Medical Center a world-class teaching hospital, one Perhaps, in two or three years, I will be able to retire. In spite of my administra- that made a point of prioritizing patients’ needs. “It was important to me, tive work, I have always found patient that message of always putting the human side of things first,” Bulger says. and family care to be the most rewarding Later, Hogness called on Bulger to become the first executive officer of the aspect of my medical career. I have a few Institute of Medicine. Bulger served in that capacity from 1972 to 1976. four-generation families in my practice. It will be difficult to say goodbye in a few “I learned so much about patient care and how to sustain it. We have years. To all of my classmates: I hope that to work hard to keep our values in place and to learn how to be equitable,” your life inside and outside of medicine he says. has been as blessed as mine. I have been truly lucky.” These days, Bulger is still concerned with equity; in fact, he’s helping develop a new nonprofit, the American Council on Health Equity and 1979 Disparities, a resource for healthcare professionals who need to keep up to Alan Dappen, M.D., writes, “I am a date on issues related to access to care. “In the political world and in our family doctor and have lived and worked culture,” he explains, “it’s hard to see through it all.” in northern Virginia (very near the other Washington) since 1992. Thirteen years Read the full version of Bulger’s story online at uwmedmagazine.org. ago, I left my former practice to start a consumer-driven medical practice called DocTalker Family Medicine. It was built 1976 on the question, ‘How would I have to Save the date for your behave and shape my medical practice 40th reunion: Friday, June if the patient (and not the insurance 3–Saturday, June 4, 2016! company) paid my bill and was my only boss?’ Last year, I was unexpectedly Dean Kashino, M.D., handed two awards: the Global Health writes, “I am still practicing Award by William Hazel, M.D., secretary family medicine in Santa of health for the State of Virginia, and Cruz, Calif. I am married the Doctor Changing the World Award to Frances, my wife of 37 by the Family Medicine Education years, and we have two Consortium.” grown children. I delivered Douglas Phillip, M.D., MPH ’86, babies until 1998, when I writes, “So thrilled my award-winning, started to be a part-time medical-suspense novel, Spirit Made James Mhyre, M.D., during the installation administrator. I was chief Smaller, was listed by MEDSCAPE.com of his artwork in the Foege Building. of staff of our local hospital, Dominican, in its ‘Readers’ Picks: Best Summer which is the only full-service hospital in Reading’ compilation. In February, I our county. (We have cardiac surgery, completed a book-signing tour in the neurosurgery and a Level III neonatal

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Hawaiian islands. The most memorable years — what an amazing group! Sorry 1983 signing event occurred at Hanapepe on to have missed the 35th reunion, but M. Kim Lynch, M.D., an Idaho the island of Kaua’i at Talk Story Book- my son’s college graduation took physician-preceptor (general surgery), store as part of the weekly Hanapepe precedence. Hope to be at the 40th.” was honored with the WWAMI Distin- Festival and Art Walk. Talk Story touts E. Franklin Livingstone, M.D., guished Teacher Award, presented at the that it is ‘the western-most bookstore in Res. ’83 (physical medicine and UW School of Medicine graduation on the United States.’ (I suspect there may rehab), MOT ’83, writes, “Physiatry was May 22, 2015. be a bookstore or two farther west in a great choice for me. I’m still practic- Nome, Alaska — I haven’t visited there ing after 32 years, and I love my work. I yet to verify if one is still open for busi- mostly do musculoskeletal and peripheral 1984 ness). Most of the first chapter of the nerve diagnosis and also some forensic book is set on Kaua’i before the story physiatry in Lake Havasu City, Ariz. (best shifts to Kamchatka Peninsula in Alaska. weather in the known world). My son, For more information, please visit Jason, was just accepted to the spiritmadesmaller.com.” University of Texas School of Medicine in San Antonio. Please look me up if you are coming to Lake Havasu City (find me on the internet, not the phone book, but in the white pages).” C. Scott Smith, M.D., Res. ’89 (internal medicine), UW professor of medicine and of biomedical informat- ics and medical education, based in Boise, Idaho, received the 2015 WWAMI Alumni Award for Excellence in Mentor- Louise Kirz, M.D., writes, Tim Teusink, M.D., Res. ’82 ing, Teaching, Leadership and Patient “I’m happily practicing anesthesia in (family medicine), writes, “I have Care. Smith, an E-76 WWAMI graduate, Portland, Ore., where I’ve been for practiced medicine and surgery primarily was integral in leading the UW’s Internal 18 years. Before that, I was in on the African continent (Rwanda and Medicine Boise Track, now a full three- Anchorage. My boys are 18 and 22.” Ethiopia) since 1984, and I am teaching year internal medicine residency program whole-person medicine and bioethics to based at the Boise VA Medical Center. 1985 medical students and residents in Ethio- Doris Mugrditchian, M.D., MPH, pia, Kenya and other African countries. I 1981 is living in Mali. After a number of years received an M.A. in bioethics in 2013.” Save the date for your 35th reunion: with the World Health Organization, she Friday, June 3–Saturday, June 4, 2016! is working as head of the health unit for 1980 a Swiss NGO based in Lausanne. Joanne Gartenberg, M.D., Res. ’82 Ted Epperly, M.D., FAAFP, was the (psychiatry and behavioral sciences), program director and keynote speaker at writes, “After living in San Diego for al- 1987 the World Health Organization confer- most 30 years and in Juneau, Alaska, for Melissa Smith, M.D., Res. ’91 ence in Geneva, Switzerland, in April three, I am thrilled to be back in Seattle. (family medicine), has collaborated 2015. The theme of the conference was I’m enjoying my job as medical with Hesperian Health Guides writers person-centered primary healthcare. director at Community Psychiatric Clinic. and editors in more than 20 countries Epperly was appointed by the governor I’ve been married to Rabbi Dov Garten- over the past four years. The result is of Idaho to chair the board of the Idaho berg since 2010, and we have four kids the publication of the Health Action Healthcare Coalition, and he was named between us. The youngest just graduated Guide for Women and Girls, a book that one of eight CEOs of influence in 2015 from Whitman College. Would love to will include activities and strategies to in Idaho Business Review; in addition, he connect with classmates!” help tackle difficult discussions about received UW Medicine’s Alumni Service Sandra (Juul) Ledbetter, M.D., sexuality, family planning, safe mother- Award in 2014. Res. ’84, Res. ’89 (pediatrics), Ph.D., hood, unsafe abortion, HIV and violence Rick Harrison, M.D., writes, “After became head of the Division of against women, among other topics. The nearly 30 years as a pediatric intensivist Neonatology at UW Medicine in impetus for the publication was her work at UCLA, I have shifted completely to an January 2015. She is continuing her work in Liberia and Nicaragua. administrative role as CMO of Ronald on perinatal neuroprotection for neonates Reagan UCLA Medical Center. I miss the at high risk of brain injury. She is also clinical care, but it is nice to have my the PI of a multicenter trial to determine nights and weekends back. I enjoyed whether high-dose erythropoietin, given being a HOST for a few UW School of in the neonatal period, will improve the Medicine students over the last couple neurologic outcome of extremely preterm infants.

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1988 1995 Chris Holdhusen, M.D., writes, “I’ve lived in White- fish, Mont., since 1996 and have no regrets about that. Kathy and I raised three kids: two are in college and Eric, the last one still home, is a freshman. For the past eight years, I have worked at a community health center I helped get started. That has required me to use everything I learned at the UW (except how to draw the Krebs cycle). Hello to all Deborah Tepper, MSN, M.D., my beloved classmates.” Res. ’98 (internal medicine), writes, “I have left the Cleveland Clinic and accepted a position with Beth Israel Brian Roth, M.D., Res. ’89 (internal 1991 Deaconess on Cape Cod. This is a medicine), Res. ’92 (ophthalmology), location near and dear to me. I am writes, “There’s nothing more fun than Save the date for your 25th reunion: board-certified in headache and internal taking your kids fishing!” Friday, June 3–Saturday, June 4, 2016! medicine, and my practice will be a mix Cdr. Abhik Biswas, M.D., writes, “I of these specialties. My husband has 1989 retired from the Navy in 2012, but I am accepted a position at the Geisel School still working for the Navy at the Naval Barbara Detering, M.D., was the of Medicine at Dartmouth College and Medical Center Portsmouth in Virginia first woman elected to serve as chair of will be commuting to the Cape for as the medical director of the PICU and the Group Health Physicians board of long weekends.” directors. Detering has been a physician division head of pediatric critical-care at Group Health since 1991, when she medicine. Additionally, I serve as the 1997 joined their family medicine residency. associate medical director of inpatient Theodore Houk, M.D., writes, pediatrics at Cape Fear Valley Medical Rob Hilvers, Jr., M.D., is the CEO “Pamela and I were married about 31 Center. We’re now empty-nesters, as the and founder of the Emergency years ago and drove 3,000 miles over last kid headed off to college this fall!” Responders Health Center in Boise, four days to start medical school. I was Idaho. The clinic provides exams, fit- struck by a car going 38 miles per hour 1993 ness, physical therapy and education for first responders, such as firefighters on 3/28/13. I was off nine months for Ellen Pierce, M.D., Res. ’98 and police. Hilvers has been involved in bone repair. I am back to running 15 (pathology), has a great-nephew, Ethan multiple wilderness medicine expeditions miles a week, not the usual 28. My Ericksen, who enjoys his UW School of as a volunteer physician for the Hima- oldest son, Cliff, just entered Virginia Medicine bib — but his mother won’t let layan Rescue Association, as a climber Tech Carilion School of Medicine and him wear it when he eats. Research Institute. We moved him down and team physician on Denali, and as an from Baltimore to Roanoke. My brother expedition physician to the Antarctic and and sister-in-law, Drs. Gary Houk and South Pacific. Carolyn Houk, moved to Seattle to watch our 79-year-old mother. If you need help 1998 with legislators, I know them: D.C. Amanda Paulovich, Ph.D. ’96, M.D., is close.” UW associate professor in medical oncology, has received the 2015 1990 Distinguished Achievement in Proteomic Sciences Award from the Human Suzanne Harrison, M.D., Res. ’92 Proteome Organization. (family medicine), was named an exceptional mentor by the American Medical Women’s Association (AMWA).

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1999 LeeAnna Muzquiz, M.D., is The Olympian newspaper. That publicity medical director of Polson Tribal Health in generated so many inquiries that I was Melissa (Moe) Hagman, M.D., the Missoula, Mont., area. She’s serving able to complete my clinical trial quickly. Res. ’02 (internal medicine), Chief as the liaison between the tribal com- I am preparing the results for publication, Res. ’03 (internal medicine), was munity and researchers at the University and I’m now planning a larger follow-up inducted into the Gold Humanism Honor of Montana as the groups work together study.” Society this past spring. She is a UW to conduct pharmacogenetics research. associate professor in the Department She also received the 2014 George Saari 2007 of Medicine and the associate program Humanitarian Award from Montana director of the Boise internal medicine State University. residency program. She teaches medical students and residents at the Boise VA 2001 Medical Center. Save the date for your 15th reunion: 2000 Friday, June 3–Saturday, June 4, 2016! Greg Davis, Will Smith, M.D., was recently M.D., MPH named an EMS (emergency medicine ’03, Res. ’07 services) Medical Director of the Year in (otolaryngol- Wyoming. He shares the honor with ogy), writes, colleague A.J. Wheeler, M.D. “I would have Melissa (Lofgren) Molsee, M.D., loved to attend 2004 Res. ’10 (general studies), writes, “I my reunion, Lucinda Grande, M.D., Res. ’04 am living and working in Togo, West but I was sum- (internal medicine), Res. ’08 Africa, at a mission hospital. This past miting Mount (anesthesiology), writes, “My research March, my husband and I were privileged Rainier! All on oral ketamine for chronic pain was to assist with the opening of the Hospital went well.” featured in a front-page article in of Hope, a 40-bed mission hospital providing critical surgical, medical and obstetrical care in northern Togo, West Mingling Healing Africa. Since then, more than 8,000 people from Togo and six surrounding and Religion countries have come through our doors. Laila Zomorodian, M.D. We look forward to raising our four “Umbrellas are used year-round young boys here and continuing to serve the people of West Africa. For more in- in Ethiopia — they protect from formation about our hospital, please visit the sun as well as the rain,” says our website, hospitalofhopemango.org.” Laila Zomorodian, M.D. ’15. She discovered this while working as a 2008 SCOPE fellow in Gondar earlier this Crystal North, M.D., writes, “I just year. SCOPE (Strengthening Care completed a pulmonary and critical-care Opportunities Through Partnership fellowship at the Harvard combined in Ethiopia) partners with medical fellowship program of Massachusetts General Hospital, Brigham and Women’s and faith communities to improve health. The UW Department of Global Hospital and Beth Israel Deaconess Health, the University of Gondar, and members of churches in the U.S. Medical Center. I have been selected as and in Ethiopia participate. a 2015–2016 Fogarty Global Health Fellow, and I will be spending the next It’s a good tactic; while reports estimate that Ethiopia has only 2,000 year in Mbarara, Uganda. I’ll study the physicians, it has 500,000 Orthodox priests. Zomorodian implemented and epidemiology of chronic lung disease evaluated two pilot projects to train priests and other religious leaders to in people living with HIV under the refer women to local health clinics. When the training was complete, vol- mentorship of Dr. David Christiani of unteers received umbrellas as a “thank you,” as shown in the photograph. the Harvard T.H. Chan School of Public Health and Dr. David Bangsberg of the Zomorodian’s visit to Gondar was one of a number of experiences that Massachusetts General Hospital Center convinced her to pursue surgery, and she’s now a resident at East Carolina for Global Health.” University. Her goal? “I want to become a well-rounded surgeon who can serve and advocate for the poor,” she says.

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2009 Allergy and Infectious E. Donnall Thomas, Sr., M.D., UW professor of Medicine, as well as the father of Twiggy Diseases epidural conduction anesthesia in Lee, M.D., Benjamin Lipsky, M.D., Res. ’73, obstetrics, the late John J. Bonica, M.D., writes, “Logan Res. ’76, Chief Res. ’77, Fel. ’78, founder of UW Medicine’s Department Adam Lau was writes, “Three years ago, I transitioned of Anesthesiology and Pain Medicine. born at UW (becoming professor emeritus) from the labor and de- Department of Medicine at the Internal Medicine livery on March UW (based at the VA Puget Sound) to 5, 2015, on a the Division of Medical Sciences at the Grant Hughes, M.D., Res. ’03, full moon! He University of Oxford (based at Green Res. ’05, UW associate professor of was delivered Templeton College). I have greatly rheumatology and Harborview Medical by Dr. Karen enjoyed having more time for clinical Center section chief in rheumatology, Bar-Joseph, research, scientific writing, teaching has been named the Robert F. Willkens, fellow and traveling worldwide as a speaker M.D.-Lucile T. Henderson Endowed UW graduate and consultant, mostly for work related Professor in Rheumatology. (2008).” to foot infections in diabetic patients. Caroline Hurd, M.D., Res. ’10, Serving as visiting professor of medicine was part of the Puget Sound Business Weiya (infectious diseases) at the University of Journal’s “40 under 40” list in 2015. (Zhang) Geneva has also been a wonderful aca- Hurd, a UW clinical assistant professor Wysham, demic and cultural experience. Receiving in internal medicine and director of M.D., and the Karel Bakker Award from the Interna- education operations at the Cambia Nicholas tional Working Group on the Diabetic Palliative Care Center of Excellence, is a Wysham, Foot was a career highlight; this lifetime physician at Harborview Medical Center. M.D., achievement award is presented once welcomed their every four years at the largest diabetic Microbiology son, Benjamin, foot meeting worldwide, held in The Devorah Bennu, Ph.D. ’02, writes, in February Netherlands.” “After receiving my B.S. in microbiology 2015. and immunology (emphasis in virology), 2009 alumnae and babies, from left I took two years off to earn some money to right: Lisa (Nguyen) Dang and her by working at Fred Hutchinson Cancer daughter, Cora, Allison Porter and her Research Center. I then returned to earn son, William, Weiya (Zhang) Wysham my Ph.D. in zoology (2002), followed and her son, Benjamin, and Twiggy Lee by a two-year Chapman postdoctoral and her son, Logan. fellowship (ornithology) at the American Museum of Natural History in New York City. I now write a popular science blog for The Guardian online (theguardian. From left to right: Prof. Nicolaas Schaper, com/science/grrlscientist) and specialise Donna M. Lipsky, Benjamin Lipsky, M.D., in rigorous long-form pieces about and Dr. Karel Bakker, the “godfather” of evolution, ecology and behaviour, the diabetic foot world. especially in birds — although my most recent stories have mostly been about Family Medicine non-avians! When I know people from UW are reading my writing, I feel Scott R. Dunn, M.D., Res. ’92, was especially satisfied and happy, like I am named the 2015 Idaho Family Physician giving back to my academic community.” of the Year at the 67th annual confer- ence of the Idaho Academy of Family Nephrology Physicians in May 2015. He serves as the Your Baby — Daniel Lam, M.D., Res. ’10, Sandpoint WRITE/TRUST site co-director In Their Very Own Bib! UW clinical assistant professor, has and R/UOP preceptor for Idaho WWAMI. This issue contains some beautiful been selected by the Cambia Health babies wearing the best accessory Hematology Foundation as a 2015 Sojourns Scholar. that mealtime has to offer: the official His project: “Integrating Palliative bib of the UW School of Medicine. Augustine Perrotta, D.O., Fel. ’70, Care in the Dialysis Facility: A Systems If you’d like a bib for your baby, just has written a book, A View from the Approach.” email us at [email protected]. Inside, that pays tribute to the father of Then send us a photo! bone-marrow transplantation, the late

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Ophthalmology Seattle increasing number of students to pre- cept. This last school year, there were 15 Starla Fitch, M.D., Res. ’91, gave a total from all three MEDEX sites. MEDEX TEDx Talk on connection and perception proved prophetic in this regard. It has that has more than 6,000 views. To view been a rejuvenating experience. Cer- it, look up “connect or die” on YouTube. tainly, there are many issues to overcome in our healthcare system, but I am not Pediatrics worried about the character or ability of Henry “Rennie” those I’ve seen who are to follow. They Coit, M.D., Res. ’89, have all been great, and it has given me MBA, was appointed a much better outlook on the future, chairman of the Board of both for the profession and in general. PaxVax, Inc., a company I expect that someday I and those I love focusing on vaccines for will be under their care, and I am fine John D. Patz, PA-C (Seattle the developing world. with that.” Class 12), D.O., writes, “Following Rehabilitation Medicine MEDEX, I practiced as a PA for five years while completing my undergraduate Steve Barbuto, DPT ’06, received an education. In those days, the future of American Physical Therapy Association PAs was unclear, and I was still pretty Emerging Leader Award. young. I went on to medical school. Susan Michaud, DPT ’07, was After an internship, I served in the Indian named Physical Therapist of the Year Health Service in New Mexico before by the Physical Therapy Association of returning to Seattle, where I completed a Washington. family medicine residency. During those years, I enjoyed teaching in the MEDEX Rheumatology Northwest program and am proud to Andrew Holman, M.D., Fel. ’92, have received the Golden Apple Award writes, “A new diagnostic test from twice! I worked in family medicine until 2003, when I shifted my practice Seattle biotech Inmedix, where I am the Nanette Laufik, PA-C (Seattle to addiction medicine. I came back to CEO, nearly triples the rate of rheuma- Class 19), writes, “I’m back in the U.S. the University of Washington to obtain toid arthritis disease control from 27 and employed by Providence Health in a certificate in medical management percent to 79 percent by application of Portland, Ore., doing a combination before assuming my current job. Late in an overlooked element of personalized of urgent care and family medicine. I my career, I am having the challenge of medicine: the autonomic nervous system returned in late 2013 after four years in my life. I work for Evergreen Healthcare (ANS). Next, we’re working on doing the the tropics of Australia. I originally trav- in their facility in Monroe, Wash., where I same for systemic lupus erythematosus eled there to participate in a pilot project am medical director of a residential treat- and multiple sclerosis.” to introduce PAs to the Queensland, ment program; I also maintain an out- Australia, government healthcare system. patient practice. I am actively involved in Surgery I spent three additional years coordinat- working to integrate addiction treatment ing clinical skills for fourth-year medi- Peter Rhee, M.D., MPH, Fel. ’95, into traditional medicine. Not an easy cal students and working part-time in Fel. ’96, who was the attending task! My best to all my PA colleagues chronic disease care in an aboriginal physician for U.S. Representative who I have worked with over the years.” clinic. My husband, a retired pilot, and I Gabrielle Giffords of Arizona as well as Forest Hofer, PA-C (Seattle travel as often as possible.” other victims of the 2011 Tucson shoot- Class 14), writes, “I recall when I was Laurie E. ing, recently published a memoir: Trauma a MEDEX student that we had a lecture Benton, Ph.D., Red: The Making of a Surgeon in War and discussion on what our career trajec- PA-C (Seattle and in America’s Cities. tory would be about. There was the Class 26), Heather Evans, M.D., Fel. ’08 expectation that our early years would writes, “After (surgery), UW associate professor of be about paying our dues. This would be graduating surgery, was featured in Seattle Magazine followed by our “power” years, where from MEDEX, I in July. She’s leading the development of you would realize your fiscal and career was given the a smartphone app that will help patients potential. Finally, there would be the opportunity to and physicians monitor post-surgery payback years, where you would teach learn and work healing and infection by allowing patients and volunteer. I have definitely reached in cardiotho- to send photos of incisions to their the payback part. For the last 22 years, racic surgery, care team. I have worked in White Salmon, Wash., nephrology, at a rural hospital emergency room. For hospital the past few years, I have had a steadily

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medicine and now hospital administra- can be provided in the field. Additionally, tion. I owe a large “thank you” to the PAs by sending advanced practice provid- who elected me to the board of directors ers (APPs) to the scene, we are able to of the American Academy of Physician As- ensure that engine and ladder crews are sistants. There have been so many oppor- available to respond to true emergencies. tunities and journeys that have come my Our team of APPs works out of three fire way since becoming a physician assistant. stations, providing 24/7 coverage 365 I have been able to share my training with days a year. We stay at the fire stations underserved clinics, rescue operations, for 24-hour shifts, along with the engine the Texas Medical Rangers — and during and ladder crews. We work in a two- other challenges, such as the Fort Hood person crew system, with an APP and an shootings and hurricanes Katrina and Rita. Here, I am able to continue my com- MFMD captain-paramedic, and we’re dis- When not working as a PA, I am able to mitment to underserved populations as patched though our 911 dispatch center work with rescued and abused animals.” recognized by the Richard H. Layton, to non-life-threatening calls. We see and Steve Platz, M.D. Award, granted to me upon gradu- treat minor lacerations, infections, mild PA-C (Seattle ation from MEDEX. At the VA, I work in asthma exacerbations, allergic reactions, Class 30), outpatient clinics, first-assist in surgeries, nausea and vomiting, etc., and are able writes, “Since precept PA students and am chair on the to provide jail clearances in the field. We graduation, I professional standard boards. I also was use a larger ambulance-truck unit, with have been for- recently appointed by the chief of staff all of our supplies onboard — basically, tunate to blend as the lead VA facility PA-C. Serving the we operate as a small, mobile, urgent- my passions veterans of America has been the most care unit. This is a new and exciting for medicine, rewarding part of my career. I am able to career opportunity for PAs. Other pro- fitness and the provide quality healthcare to my patients, grams have sprung up nationally based outdoors. I’ve who have risked their lives to make and on the Mesa program. Recently, I met fire been living keep America strong and free. Being a chiefs from Lacey and Olympia, Wash., and working in PA-C has given me the opportunity to be who came for a site visit. They hope to Lander, Wyo., a proud homeowner in Marin County, establish similar programs.” (pop. 7,500) where I’ve lived with my son Diego since for the past 2002. I’ve been blessed with two addi- decade. Lander has a wonderful blend of tional children, Violet and Caden, along citizens, from multi-generational ranch- with my lifelong partner, Mike Meyer. My ers to rock climbers, and energy industry PA-C career has been a happy work-life employees to teachers. Working in family balance, loaded with epic adventures like practice and psychiatry provides me with road trips, traveling, hiking, camping, a wide variety of patient experiences. snowboarding and just barbecuing in my I served as president of the Wyoming own backyard with family.” Association of Physician Assistants and Jody remain active with our version of WAPA. Sanderson, Last year, I completed my first IRONMAN PA-C (Seattle triathlon, and I appreciate the opportuni- Class 32), M.S., ty to escape into the mountains regularly writes, “I work in with my wife and teenage daughter.” a very interesting Patrick, Parenzin, PA-C, with Seattle Gina Franco, PA-C (Seattle and cutting-edge Children’s coworkers and Special Olympics Class 32), writes, “My life after MEDEX job as a PA, one Washington volunteers. has been a joyful experience, filled with of the very first amazing opportunities in both my career of its kind in the Patrick Parenzin, PA-C (Seattle and personal life. Upon graduation, United States. My Class 39), writes, “I went straight from I accepted a fellowship training at UCSF’s position is that MEDEX to Seattle Children’s, where I orthopedic surgical department in which of a pre-hospital have been working in pediatric orthope- I gained immense orthopedic surgical PA, working with the Mesa Fire Medical dics for close to eight years now. The or- training, was published in the Journal of Department (MFMD) through a joint ven- ganization has a great mission, and they the American Academy of Orthopaedic ture with Mountain Vista Medical Center continually support me in my volunteer Surgeons, and was a speaker at ortho- in Mesa, Ariz. I work on the community work with Special Olympics Washington pedic meetings in California and Hawaii. care unit. The premise behind this pro- as the Healthy Athletes MedFest clinical Soon after, I was hired as chief ortho- gram is to keep patients with non-life- director. MedFest is a Special Olympics pedic PA-C in my dream job at the threatening illnesses from utilizing the program offering free, comprehensive San Francisco VA Health Care System. emergency department when their care pre-participation physical exams. My

44 UW MEDICINE < MEDEX ClassNotes

hope is that this program continues to Spokane Montana. Years ago, I lived and worked grow and serve those with intellectual in Polson as a paramedic. Today, I treat disabilities here in Washington state.” folks in the emergency department that Parenzin received the 2015 MEDEX I treated as an EMS provider 20 years Excellence in Teaching Award. ago! I’ve completed the NCCPA certifi- cate of added qualification in emergency medicine, and I’m really close to realizing another lifelong dream of becoming a licensed pilot. Being a MEDEX graduate has changed my life, and I’m so grateful for the opportunity to be practicing as a physician assistant.”

Dana S. Harvey, PA-C (Spokane Class 4), writes, “It was my good fortune to take my first drink from the medical fire hose with MEDEX Spokane Travis Baker, MCHS, PA-C (Seattle Class 4, an eclectic, tie-dye-shirted group Class 45), writes, “In January, I complet- that graduated in 2002. The majority ed an emergency medicine fellowship at of my career has consisted of providing Baylor College of Medicine in Houston, patient care in Montana’s rural critical-ac- Texas. As a former firefighter/paramedic, cess hospitals, often as the sole provider I was able to network with our emer- on duty. It’s frontier medicine, defined by gency medical services (EMS) colleagues, days of benign runny noses and all-too- and I was offered the position of clinical frequent head-scratching cases, director for community paramedicine for periodically punctuated by moments a large EMS agency outside of Houston. Andrew Becker, PA-C (Spokane of sheer terror in the emergency room. I remain on faculty at Baylor, working Class 13), writes, “Since graduation I’m proud to say that I am a physician 80 percent of the time in EMS and 20 from MEDEX, I have primarily worked assistant striving to uphold the tenets percent in our trauma center. We address in urgent care. For the past year, I also that patient care and safety are foremost. frequent 911 users, and we have made a have worked part-time in wound care So enough about me — let’s stir the pot substantial impact in both reducing 911 and hyperbaric medicine. We added two regarding electronic medical records, utilization and improved quality of life, boys to our herd and bought a house in administrators and staff that accept resulting in healthcare cost savings. In my Moscow, Idaho. My wife continues to mediocrity, and the leaky trauma free time, I enjoy sand volleyball, college operate her landscape design business dressing labeled Obamacare.” football and exploring the outdoors.” out of our home — she’s a busy lady. I received EMT of the Year from the Veterans of Foreign Wars and was given a life-saving award for leading a team that successfully resuscitated an out-of- hospital pediatric cardiac arrest. My MEDEX training has provided for us well.”

Tim Thornton, PA-C (Spokane Class 8), writes, “I have come full circle after graduating from MEDEX. It wasn’t Janice Sim, PA-C (Seattle Class 45), easy! MEDEX faculty and leadership M.A. ’13, welcomed daughter Cameron stuck with me, and I persisted. I am Sim, who was born on July 2, 2014, and is so grateful I did. I work in emergency enjoying her UW School of Medicine bib. medicine at a critical-access hospital on the Flathead Indian Reservation in

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Robert E. Condon, M.D., Int. ’58, Res. ’65 (general surgery), M.S., PASSAGES: OUR FRIENDS, REMEMBERED FACS Below we pay tribute to recently deceased alumni, faculty, students Dr. Condon published 21 books and and friends. Because we are not always aware of deaths in the larger 101 book chapters. UW Medicine community, we gratefully accept your notifications. Our sincere condolences to those who have lost loved ones. Ross D. Kennedy, M.D. ’65, Res. ’74 Please see uwmedmagazine.org for full obituaries. (anesthesiology) Dr. Kennedy, in 1958, became the youngest person to summit Mt. Lloyd R. Lichty, M.D. ’56 ALUMNI McKinley. Dr. Lichty was a corpsman in the Randy Robyn, M.D., Res. U.S. Navy, and he played the trumpet Bob W. Brawley, M.D., Res. ’66 (family medicine) and guitar. Dr. Brawley pioneered techniques in Michael Jayko, M.D., Res. ’52 neurosurgery. Lester R. Sauvage, Sr., M.D., Res. ’56 Dr. Jayko was a nuclear chemist. (general surgery) Gary L. Huber, M.D. ’66 Theodore C. West, Ph.D. ’52 Dr. Sauvage founded a lab that later Dr. Huber founded the Texas (pharmacology) became known as the Hope Heart Nutritional Institute at East Texas Dr. West was a researcher, an Institute. Please see his obituary on Medical Center. expert in medical education and a page 48. Bruce J. Wolf, M.D. ’67, Res. ’71 beloved mentor. Darrel E. Stavig, M.D. ’56, Int. ’57 (ophthalmology) W. Wyman Andrus, M.D., Res. ’53 Dr. Stavig was in the Merchant Dr. Wolf delivered care by dogsled in Dr. Andrus was a cardiologist; he loved Marines and in the U.S. Army. the U.S. Public Health Service. sports and played the trumpet. Donald P. Schumacher, M.D., David T. English, M.D. ’68 Thomas S. Gilpatrick, M.D. ’53 Res. ’57 (anesthesiology) Dr. English loved sports and Dr. Gilpatrick believed in affordable Dr. Schumacher practiced in the photography. healthcare for women. Seattle area for many years. Thomas E. Schwark, M.D., Res. ’68 Horace G. Moore, Jr., M.D., Res. ’53 John H. Vogel, M.D. ’57, MACC, (pediatrics) (general surgery) FSCAI Dr. Schwark served as CEO of Wyman Dr. Moore was the first surgeon in Dr. Vogel was an innovator in Park Medical Center in Baltimore. Wilmington, Del., to perform surgery cardiovascular care. Please see his Robert Walter Mejo, M.D., Res. ’69 obituary on page 49. for an aortic aneurysm. (psychiatry and behavioral sciences) Bertram R. Pass, M.D. ’53 John A. Wolf, Jr., M.D. ’61, Res. ’66 Dr. Mejo led negotiations between Dr. Pass delivered more than 2,400 (urology), FACS police and the Black Panthers. Dr. Wolf was a UW clinical professor babies in a 40-year career. Norman F. Peterson, M.D. ’69 emeritus. Richard Layton, M.D. ’54 Dr. Peterson founded Peninsula Behav- Dr. Layton was a pioneer in the five- Thomas J. Hansen, M.D. ’62 ioral Health in Clallam County, Wash. Dr. Hansen was a captain in the state WWAMI educational program. Donald B. Reece, M.D. ’71 U.S. Air Force. Please see his obituary on page 48. Dr. Reece practiced family medicine Donald W. Sample, M.D. ’55 Donald W. Hegge, M.D. ’63, Res. ’68 for more than 40 years. (urology) Dr. Sample served in the military for Terry L. Lanes, M.D. ’72 30 years. Dr. Hegge was the only urologist on the North Olympic Peninsula for 13 years. Dr. Lanes went on five medical Jonathan Holloway, M.D. ’56 missions to post-earthquake Haiti. Dr. Holloway was ophthalmologist and an Episcopal deacon. Please see his obituary on page 48.

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Joshua S. Obak, M.D. ’72, FAAP, Paul A. Swinehart, Jr., M.D., FRIENDS FACEP Res. ’82 (anesthesiology) Dr. Obak was fluent in five languages. Dr. Swinehart enjoyed music, history Robert Campbell Coe, M.D. and adventure novels. Dr. Coe was a surgeon and Janet E. Mules, M.D., Res. ’73 philanthropist. Please see his obituary (psychiatry and behavioral sciences), Terence Calderwood, M.D. ’86 on page 50. Res. ’74 Dr. Calderwood was a pilot and an Dr. Mules was a psychiatrist for the accomplished marksman. Jane Isakson Lea U.S. Foreign Service. Mrs. Lea enjoyed Scandinavian culture Carrie Lynne Volk, B.S. ’90 and supported medical research. Please Richard J. Weiland, M.D. ’73 (physical therapy) see her obituary on page 51. Dr. Weiland served as medical director Ms. Volk served as director of physical of Tri-State Memorial Hospital Home medicine at Auburn Regional Medical Frank Wilson Pritt III Health and Hospice. Center. Mr. Pritt was a businessman and philanthropist. Please see his obituary Carl T. Bell, M.D. ’75 Yasmin A. Ahmedi, M.D. ’09 on page 51. Dr. Bell was a gifted writer, producing Dr. Ahmedi was a highly regarded a children’s book, numerous plays pediatric gastrointestinal fellow. Ellyn W. Swanson and songs. Please see her obituary on page 49. Mrs. Swanson was president of the Friends of the UW School of Karen Anderson, M.D. ’76, MPH FACULTY AND Medicine. Please see her obituary on Dr. Anderson cared for veterans, the page 51. developmentally disabled and those FORMER FACULTY with little means. Alexander Whitehill Clowes, M.D. David Earl Gambill, M.D., Res. ’76 Dr. Clowes was a vascular surgeon and (diagnostic radiology) philanthropist. Please see his obituary Dr. Gambill was a flight surgeon in the on page 50. U.S. Air Force. Robert F. Labbé, Ph.D. Brad Stanley Jordan, B.S. ’77 (physical Dr. Labbé was recognized for outstand- therapy), DMT (Hon.), FAAOMPT ing contributions to clinical chemistry. Mr. Jordan was the CEO, COO and Please see his obituary on page 50. director of clinical education at the Roy Mark Mays, Jr., Ph.D., J.D. Ola Grimsby Institute. Dr. Mays ran for Washington state’s Wayne Katon, M.D., Res ’79 5th congressional district in 2008. (psychiatry and behavioral sciences) Jerrold M. Milstein M.D. Dr. Katon was a leader in Dr. Milstein served as director of the collaborative mental health care. division of pediatric neurology at Please see his obituary on page 49. Seattle Children’s. Thomas M. Robbie, M.D., Res. ’80 Daniel Charles Moore, M.D. (family medicine) Dr. Moore was a faculty member in Dr. Robbie practiced emergency anesthesiology. medicine in Washington for 25 years.

Sharon Kate Crowley, B.S. ’81 (physical therapy) Ms. Crowley loved outdoor activities and raising sheep, goats, cows and horses.

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ALUMNI Jonathan Lester R. Holloway, Sauvage, Richard M.D. ’56 Sr., M.D., Layton, Born Feb. 24, 1930, in Res. ’56 M.D. ’54 Seattle, Wash. (general Born March 13, Died July 8, 2015, in surgery) 1927, in Fond du Spokane, Wash. Born Nov. 15, Lac, Wis. Born in Seattle, Dr. Jonathan 1926, in Wapato, Died June 8, 2015 Holloway attended Garfield High Wash. Dr. Richard Layton graduated at School, Stanford University and Died June 5, 2015 the top of the fifth graduating class of Oberlin College, followed by the Dr. Lester Rosaire Sauvage, Sr., the UW School of Medicine in 1954. UW School of Medicine. He spent attended Gonzaga University and After interning at Detroit Receiving two years as a flight surgeon for the Saint Louis University School of Hospital, he was a member of Yakima U.S. Air Force before completing Medicine in Missouri. In 1949, he Valley Clinic in Grandview, Wash., an ophthalmology residency at the completed a one-year internship at from 1955 until 1974. Dr. Layton Wills Eye Hospital in Philadelphia, King County Hospital (now Harbor- was a pioneering physician in the Pa., where he served as chief resident view Medical Center) and began a UW School of Medicine’s WWAMI surgeon from 1961 to 1962. residency in adult general and vascular program, bringing medical care to rural surgery at the UW School of Dr. Holloway and his wife, Barbara and underserved areas. Then, for 20 Medicine. After serving as a lieuten- Brewer Holloway, moved to Spokane years, he directed a family practice ant in the U.S. Army Medical Corps in 1962, where he joined a practice; “residency at Providence Hospital in during the Korean War, he met the in 1968, he joined Rockwood Clinic Seattle, focused on serving the inner love of his life, Mary Ann Marti. They as a founding partner. After retiring city. For many years of service as a clin- married in 1956, moved to Boston for from Rockwood in the early 1990s, he ical professor, Dr. Layton was awarded thoracic surgery training, then re- joined the Eye Care Team, where he emeritus status upon his retirement. turned to Seattle to launch his career practiced until 2002. In addition, In 1986, Dr. Layton was named as a cardiovascular surgeon. Over the Dr. Rockwood was ordained as a Washington state’s family physician course of his career, Dr. Sauvage per- deacon in the Episcopal church in of the year; in 2001, he received the formed more than 10,000 surgeries. 1976, served on the boards of Alumni Service Award from St. George’s School and the Spokane In 1959, Dr. Sauvage founded the UW Medicine. And in 2013, Symphony, was editor of the Spokane research laboratory that later became Governor Jay Inslee gave him the County Medical Society newsletter, known as the Hope Heart Institute. Washington State Governor’s served as a delegate to the Washington His innovative work in the early 1960s Recognition Award, followed, in state chapter of the American Medical paved the way for cardiac bypass graft 2014, by the Distinguished Alumni Society, was a member of the Spokane surgery, which continues to save lives Veteran Award from the University Rotary Club, and helped create the today. In addition, he authored 253 of Washington. Dr. Layton served in WWAMI Spokane Endowed Scholar- professional papers and several books — the U.S. Navy from 1945 to 1946 as ship in Medicine at UW Medicine. the latest, Opening Hearts, was released a second-class petty officer assessing two weeks before his death. ships destroyed by atomic bombs at Dr. Holloway is survived by his Bikini Atoll. son, two daughters, and their families, Dr. Sauvage chose medicine over including four grandchildren. the priesthood, but faith permeated ev- Dr. Layton is survived by his wife erything he did. He is survived by eight of 40 years, Marilyn, their children, children: Lester, Jr. (Catherine), John David and Adele Layton, Deborah (Mona), Paul (Debbie), Helen (Bob Layton, and Jon and Chris Layton, Santucci), Joe (Missy), Laura (Stephen Larry and Shuling Smith, Eleanor Scheer), Bill (Chrissy), Mary Ann Smith and Charles Jaffe, 10 grandchil- (Paul Huddleston), as well as his sister, dren and several great-grandchildren. Cora Fetchko, and 31 grandchildren.

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John H. Vogel, Wayne Yasmin A. M.D. ’57, Katon, M.D., Ahmedi, MACC, FSCAI Res. ’79 M.D. ’09 Born July 3, 1932, in (psychiatry Born Aug. 15, Portland, Ore. and behavioral 1982, in Seattle, Died June 1, 2015 sciences) Wash. Dr. John H. Vogel, known as the Died March 1, 2015 Died April 29, “Jack of Hearts,” attended Gonzaga Dr. Wayne Katon, UW vice chair 2015 University. After receiving his M.D., of the Department of Psychiatry and Dr. Yasmin he did a residency at Vanderbilt Behavioral Sciences, was raised in A. Ahmedi was born and raised in University and a fellowship at the Brooklyn, N.Y., earning a medical Seattle. After receiving a B.S. in University of Colorado School of degree from the University of Oregon. neurobiology from the University of Medicine. Dr. Vogel served as director His achievements include establishing Washington, she earned an M.D. from of the cardiac catheterization lab at the Division of Health Services and the UW School of Medicine in 2009. UC for 10 years, making major con- Psychiatric Epidemiology within the She then held a one-year residency in tributions to the fields of pulmonary department, bringing in more than pediatrics, working as a hospitalist at hypertension, high-altitude pulmonary $25 million in research grants, and Children’s Hospital in Oakland. She edema, and congenital and valvular spending three decades testing and was in the first year of a gastroenter- heart disease. In 1970, he moved developing models of care to make ology fellowship at Rady Children’s to Santa Barbara, Calif., where he mental health care more accessible. Hospital-San Diego when she died played a leadership role in cardiovas- This work culminated in several publi- suddenly and tragically from complica- cular care. He was the first person in cations and the evolution of a model of tions of her second pregnancy. Santa Barbara to perform thrombolytic collaborative care that is implemented Dr. Ahmedi was known by all as a therapy, coronary balloon angioplasty, in more than 150 primary-care clinics bright, sweet spirit whose generosity laser atherectomy and placement of in Washington state, including the and kindness characterized all her coronary artery stents. UW Neighborhood Clinics. interactions. She was the mother of Dr. Vogel had a passion for edu- Dr. Katon also authored several two beautiful children, a loving wife, cation and teaching: presentations, books, edited General Hospital daughter and sister, a wise and caring publishing, organizing conferences. Psychiatry and mentored junior faculty physician, and a beloved friend to many. In 1998, he became a master of the across several departments. He will The Yasmin Ahmedi Memorial American College of Cardiology, and he be awarded (posthumously) the 2015 Scholarship Fund was established was recognized by the American Heart Distinguished Service Award from the in 2015 through the generous Association and the Society for Cardiac American Psychiatric Association for a contributions of the family of Twiggy Angiography and Interventions. He lifetime of outstanding contributions. Lee, M.D. ’09, and the many friends served on numerous committees and Dr. Katon is survived by his wife, and family who knew and loved boards within the American College of Bobbi, and two daughters, Jodi and Dr. Ahmedi. The fund was established Cardiology and other associations. Rachel. The Wayne Katon Memorial to support an aspiring pediatric resident Dr. Vogel relished challenges: he Fund has been established to support who embodies the compassion, loved to run and completed eight the next generation of psychiatry humility and optimism that defined marathons. He also loved to fly, com- students; gifts may be directed to Dr. Ahmedi’s all-too-brief life. She is pleting his first solo flight in 1971. He UW Medicine Advancement, Box survived by her husband, Adnan is survived by his wife, Cynthia, and 358045, Seattle, WA 98195-8045. Ghadiali, her three-year-old daughter, his daughters: Kristen (Blabey), Nancy Zahra, and her newborn son. Clare (Davies), and Carrie Jo (Parks). Gifts to the Ahmedi fund may He is also survived by several grand- be directed to UW Medicine children and his brothers, Robert and Advancement, Box 358045, Scott Vogel. He was predeceased by his Seattle, WA 98195-8045. son, John H.K. Vogel, Jr.

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FACULTY AND FORMER FACULTY the Award for Outstanding Contributions to Clinical Chemistry Alexander Amanda, and in being a grandfather. Through Research from the American Whitehill Dr. Clowes is survived by his wife, Association for Clinical Chemistry. Clowes, M.D. Susan, her children, Aaron Patterson He is survived by his daughters, Born 1946 (Erin) and Amanda Lovelace (Blake), Died July 7, 2015 Sharlene (James Forbes) and Yvonne his granddaughters, Charlotte, Claire Dr. Alexander (Wallace Guptill), his grandchildren and Alice, his sisters, Margaret (Frank (“Alec”) Whitehill Brad and Lisa Forbes, and David (Lisa) Bowles) and Edith (Craig Huneke), Clowes was a UW professor of surgery and Rachel Guptill, and two nieces and his brother, Jonathan Clowes and chief of the Division of Vascular and five nephews. His wife, Norma (Evelyn), as well as by many nieces Surgery from 1995 to 2007. He special- Lee, and his daughter Valerie preceded and nephews. ized in peripheral vascular conditions him in death. Robert F. and held the V. Paul Gavora and Coming out ahead FRIENDS Labbé, Ph.D.with your IRA Helen S. and John A. Schilling Professor Emeritus Robert F. Endowed Chair in Vascular Surgery. Born Nov.Labbé, 12, Ph.D. 1922, remembers receiv- Robert Campbell in Portland,ing researchOre. support when starting his career. That’s why Coe, M.D. Dr. Clowes attended Harvard Died Marchthe clinical23, chemist is creating the Robert F. and Norma Born Nov. 1918, in Medical School, received surgery 2015, in Bellevue,Lee Labbé Endowed Faculty Fellowship in laboratory Seattle, Wash. training at Case Western Reserve in Wash. medicine, a fund that will support faculty in the early Died July 17, 2015, Cleveland, Ohio, completed advanced Dr. Robertstages of their careers. in Seattle, Wash. F. Labbé earned a degree from OregonDr. Labbé took advantage of training in vascular surgery at Peter new rules that, for a short time, Dr. Robert 1 State University, was awarded aallow fel people- 70 ¼2 and older to Bent Brigham Hospital in Boston, make tax-free charitable gifts C. Coe’s father, lowship from the U.S. Atomic fromEnergy their IRAs. “I didn’t calcu- Mass., and pursued research in the late it out to the penny,” says Herbert Coe, was a surgeon; so was Commission to study at ColumbiaLabbé, “but I definitely came laboratory of Dr. Morris Karnovsky out ahead.” his grandfather, Seattle pioneer Franz University, served as faculty at theIf you’re interestedUni- in making at Harvard Medical School, where he a gift from your IRA, please Hunt Coe. Robert Coe followed in versity of Oregon, and was partcontact of the UW Office of Gift developed a lifelong interest in vascu- Planning at 206-685-1001 their footsteps, entering Harvard Enzyme Institute at the Universityor [email protected], of lar biology and arterial wound healing. or check with your financial Medical School. However, his educa- In 1980, Dr. Clowes joined Wisconsin. He joined the UW advisor.Depart - tion was interrupted by World War II, UW Medicine’s Department of ment of Pediatrics and the Department during which he served as a lieu- Surgery, becoming a professor in 1990, of Biochemistry in 1957, was awarded a tenant and executive officer of the chair of the department from 1992 U.S. Public Health Service Special Fel- U.S.S. Bronstein. (He also married lowship to do research in Australia in to 1993, and chief of the Division of UW Medicine Development his high-school sweetheart, Bobby 206-543-5686 1965, and, from 1966 until 1971,[email protected] held Vascular Surgery from 1995 to 2007. www.supportuwmedicine.org (Josephine) Weiner.) After the war, Dr. Clowes also received a Lifetime a Research Career Development Award Dr. Coe remained a U.S. Navy reserve Achievement Award from the Society from the National Institutes of Health. officer, attaining the rank of lieutenant for Vascular Surgery, and his collected He spent the rest of his career at commander. Upon graduating from scientific publications fill over six UW Medicine, transferring to the Harvard Medical School, Dr. Coe volumes. However, Dr. Clowes Department of Laboratory Medicine in completed an internship and residency considered his greatest achievements 1974, where he became head of clinical at Massachusetts General Hospital. to be the care he gave his patients and chemistry in 1980. Then the Coes returned to Seattle, his mentoring of young physicians. He Dr. Labbé published approximately where Dr. Coe practiced for the next was also the president of his family’s 100 papers on wide-ranging interests, 40 years in downtown Seattle, on foundation, The Clowes Fund, and was and his research activities involved Mercer Island and at Swedish. a longtime member of the board at the pyrrole metabolism and nutrition Dr. Coe was active in various Seattle Symphony. and their interrelationships; he was professional societies and community In 1998, Dr. Clowes’ first wife, a member of numerous scientific and activities throughout his life: the King Monika Clowes, passed away. In 2000, professional organizations. He also County Medical Association, the he married Susan Detweiler, M.D., was elected a fellow of the American Seattle Surgical Society, the Pacific delighting in the family life he shared Association for the Advancement of Coast Surgical Association; he was with Susan’s children, Aaron and Science. In 1981, Dr. Labbé received also the chair of the Washington State

50 UW MEDICINE < Passages

Medical Quality Control Board and Frank Wilson Ellyn W. served several terms on the Mercer Pritt III Swanson Island City Council after he retired. Born June 5, 1940, Born Nov. 26, 1925, Dr. Coe participated in scouting with in Charleston, W.Va. in Columbia, Ill. Died July 28, 2015, Died June 16, 2015 his sons, sailed competitively — he was in Bellevue, Wash. Mrs. Ellyn a member of the Cruising Club of Mr. Frank Weinel Swanson America — and climbed (with Wilson Pritt graduated from Mrs. Coe) the 10 highest peaks in III was a philanthropist and a highly DePauw Washington state. He and Mrs. Coe successful businessman. He earned a University in also owned and ran Hidden Valley degree in electrical engineering from Greencastle, Ind., with a major in Guest Ranch in Cle Elum, Wash., Northrup University in Inglewood, mathematics, and she married for 25 years, and created the Calif., in the 1960s. Employment August G. Swanson, M.D., Res. ’58 Herbert E. Coe Endowed Chair in opportunities at Union Carbide, (neurology) in 1947. The couple Pediatric Surgery. IBM, CCI and Harris Corporation moved to Boston, where Dr. Swanson Dr. Coe is survived by his children, followed. In the late 1970s, Frank and attended Harvard Medical School; Bruce and Kim Coe, Gigi Coe and his first wife, Julia, moved to Bellevue, then, when he served in the U.S. Michael Garland, and Matthew and Wash., where Mr. Pritt worked as a Navy, the family moved around the Pam Coe, as well as several grandchil- regional sales representative selling country. After his military service dren and a great-granddaughter. mainframe terminals. The Pritts then was complete, the family relocated to founded and managed a software Washington, D.C., where Dr. Swanson Jane Isakson Lea company called Attachmate pursued a career in pediatric neurol- Born Sept. 18, 1927, in Seattle, Wash. Corporation; it became one of the ogy. In 1993, upon his retirement, the Died May 21, 2015 most successful privately held software Swansons returned to Seattle, where Mrs. Jane Lea received a companies in Washington state. Dr. Swanson had done his residency. bachelor’s degree in Scandinavian stud- ies and a master’s degree in librarianship Frank and Julia divorced in 1991, During Mrs. Swanson’s early from the University of Washington. Her and Mr. Pritt relocated to southern Seattle years, she was active in the first spouse, Johnellis Jones, died of a California. In 1994, he married his PTA, Woodland Park Church, and the brain tumor in 1971. She then married second wife, Melanie. In 2005, Girl Scouts. While in Washington, her longtime friend, James Lea, the Mr. Pritt sold his business and retired; D.C., she became active in the local founder of Cascade Design. in 2013, the couple divorced. chapter of the League of Women Voters, where she served as president. Mrs. Lea carried on her family’s Mr. Pritt enjoyed many things: his Mrs. Swanson had a strong commit- interest in the Scandinavian com- family, home improvements, cars, gar- ment to education, becoming a member munity by serving as a trustee of the dening, boating, scuba diving — and of the Friends of the UW School of Nordic Heritage Museum, becom- philanthropy. He gave away millions of Medicine, including serving as its ing a charter member and an active dollars to various causes, and, with his president, and creating the August G. dancer with Nordiska Folkdancers, gift to the Pritt Family Endowed Chair Swanson, M.D. Endowed Scholarship at and serving as a strong supporter of the in Prostate Cancer Research, became UW Medicine. Swedish Club in Seattle, Wash. — her a UW Medicine Laureate. Mr. Pritt parents had helped construct it. In is survived by his uncle, George Pritt, Mrs. Swanson is survived by her 2008, Mrs. Lea was named “Swede of his brother, Wayne Pritt, his children, children, Eric (Devon Hodges), the Year” by the club. Ronda Waite, Laura Lee Pritt and Rebecca (Simon Fitch), Margaret Darren Pritt, his stepchildren, Kelsey Vance, Emilie Long, Jenni Voorhees Mrs. Lea eventually formed the Daviscourt and Ashley Wiegman, his M.D., (Jim), and August (Lola Jane Isakson Lea Foundation, which sons-in-law, Don Waite and Jeff Jacobson). She is also survived by three supports the Swedish Club and other Daviscourt, his daughter-in-law, nieces and nephews, 20 grandchildren Swedish cultural activities in the Janine Pritt, and eight grandchildren. and nine great-grandchildren. region, and she and Mr. Lea reached the status of UW Medicine Benefactors, having supported medical research.

FALL 2015 51 Student Voices >

Out of the Ivory Tower Service learning with Jordan Seto

few months ago, Jordan Seto was It’s not surprising that Seto gravitated sitting in a roomful of volunteer to a similar program at the UW School A student leaders — members of the of Medicine: the Service Learning Health Equity Circle — when someone Resource Center. spoke up. Look at us, she said: mostly In service learning, medical students white, mostly middle- or upper-class. Most work with community programs to im- of us are not like the communities we’re prove lives. After choosing to participate serving. Are we helping or hindering? in the School’s Health Equity Circle, The discussion that followed left a real Seto set to work on the Best Starts for impression. Kids Levy, intended to increase funds for “We realized that even some of our health services for children from mar- interventions were based on our shared ginalized communities. Her responsibili- privilege,” says Seto. “I’ve been strug- ties grew, from producing documents, to gling ever since to bring my awareness of co-chairing public meetings. Then came privilege to everyday life.” the request to lead an assembly that might That said, Seto, now a 24-year-old include King County Executive Dow medical student, has been mindful of Constantine. cultural and economic differences since “I balked at first,” says Seto. “But with In Praise of she was young. Her family lived in some coaching and hand-holding, I stood Service Learning Malaysia for a year when she was 9, up in front of 129 people, including Dow’s Jordan Seto says: “I turn exposing her to extreme levels of both representative. I cracked terrible jokes to the Service Learning wealth and poverty; a trip to India when Resource Center for help, and worked the audience as best I could.” she was 12 was similarly eye-opening. Her advice, news of must- Service learning, in short, has been a attend events, and teen years were spent in a town where major inspiration for Seto, who is con- well-informed and most families didn’t have much money. thoughtful analysis. They sidering a career in family medicine. And make everyone I’ve talked It was her time at Mount Holyoke expect to hear from her in the future: to feel included and College, however, that really pushed her Seto plans to advocate not only for her welcome. They make sense of social justice to the fore. Seto patients, but also for everyone who suffers impossible tasks seem doable.” They also majored in biochemistry, but she found a from inequity. spiritual home at the college’s welcome student and “We don’t have enough community alumni participation. community-based learning program. leaders in the U.S. that are raising the For more information, “All of a sudden, I was shoved out of my contact Kelsen Caldwell voices of the underprivileged,” Seto says. ivory tower and could work with people at [email protected] or “I want to start changing that.” 206.685.2009. who didn’t have the smooth path I’d had,” Seto says.

52 UW MEDICINE

TEAMWORK: THE FUTURE OF MEDICINE

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UW School of Medicine 2016 Reunion Weekend SAVE THE DATE uwmedalumni.org/reunion Friday, June 3–Saturday, June 4, 2016

Celebrating the classes of 1951 (E-47) • 1956 (E-52) • 1961 (E-57) • 1966 (E-62) • 1971 (E-67) 1976 (E-72) • 1981 (E-77) 1986 (E-82) • 1991 (E-87) • 1996 (E-92) • 2001 (E-97) 2006 (E-02) • 2011 (E-07) • and the 50-Year Association