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Kanazawa Medical University Research Activities and Publications Kanazawa Medical University Research Activities and Publications VOL.29 2017 Kanazawa Medical University I N D E X Code DepaertmentPage Code Depaertment Page Basic Medical Science 0475 Department of Otorhinolaryngology ・・・・・・・・ 75 0100 Department of Anatomy Ⅰ ・・・・・・・・ 1 0485 Department of Head and Neck Surgery ・・・・・・・・ 77 0110 Department of Anatomy Ⅱ ・・・・・・・・ 2 0490 Department of Dermatology ・・・・・・・・ 79 0120 Department of Physiology Ⅰ ・・・・・・・・ 3 0500 Department of Urology ・・・・・・・・ 81 0130 Department of Physiology Ⅱ ・・・・・・・・ 4 0510 Department of Obstetrics and Gynecology ・・・・・・・・ 82 0140 Department of Biochemistry Ⅰ ・・・・・・・・ 6 0520 Department of Anesthesiology and 0150 Department of Biochemistry Ⅱ ・・・・・・・・ 7 Perioperative Medicine ・・・・・・・・ 84 0160 Department of Pharmacology ・・・・・・・・ 8 0540 Department of Physical and Rehabilitation 0170 Department of Pathology Ⅰ ・・・・・・・・ 9 Medicine ・・・・・・・・ 86 0180 Department of Pathology Ⅱ ・・・・・・・・ 11 0550 Department of Emergency Medicine ・・・・・・・・ 87 0190 Department of Microbiology ・・・・・・・・ 12 0570 Department of Community Medicine ・・・・・・・・ 88 0200 Department of Immunology ・・・・・・・・ 13 0575 Department of Gastroenterological Endoscopy ・・・・・・・・ 90 0210 Department of Medical Zoology ・・・・・・・・ 14 0577 Department of Cardiovascular Intervention ・・・・・・・・ 92 0220 Department of Pathology and Laboratory 0580 Department of Oral and Maxillofacial Surgery ・・・・・・・・ 93 edicine ・・・・・・・・ 15 0590 Department of Regenerative Medicine ・・・・・・・・ 95 0230 Department of Social and Environmental Medicine ・・・・・・・・ 17 School of Nursing 0240 Department of Epidemiology and Public Heaｌｔｈ ・・・・・・・・ 19 8010 Fundamental Nursing ・・・・・・・・ 96 0250 Department of Legal Medicine ・・・・・・・・ 22 8040 Maternity Nursing・Midwifery ・・・・・・・・ 97 0260 Department of Medical Education ・・・・・・・・ 23 8050 Pediatric Nursing ・・・・・・・・ 98 8060 Adult Nursing ・・・・・・・・ 99 Clinical Medicine 8070 Gerontological Nursing ・・・・・・・・ 100 0300 Department of Cardiology ・・・・・・・・ 24 8080 Community Health Nursing ・・・・・・・・ 101 0310 Department of Respiratory Medicine ・・・・・・・・ 26 8085 Psychiatric and Mental Health Nursing ・・・・・・・・ 102 0320 Department of Gastroenterology ・・・・・・・・ 28 8090 Home Care Nursing ・・・・・・・・ 103 0325 Department of Hepatology ・・・・・・・・ 30 8100 Medical Science ・・・・・・・・ 104 0330 Department of Nephrology ・・・・・・・・ 32 0340 Department of Diabetology and Endocrinology ・・・・・・・・ 34 Department of General Education 0350 Department of Hematology and Immunology ・・・・・・・・ 37 8610 Natural Science ・・・・・・・・ 106 0360 Department of Neurology ・・・・・・・・ 40 8620 Human Science ・・・・・・・・ 108 0363 Department of Medical Oncology ・・・・・・・・ 42 0366 Department of Infectious Diseases ・・・・・・・・ 44 University Hospital 0368 Department of General Internal Medicine ・・・・・・・・ 46 0675 Health Evaluation Center ・・・・・・・・ 110 0370 Department of Geriatric Medicine ・・・・・・・・ 48 0380 Department of Pediatrics ・・・・・・・・ 49 Medical Research Institute 0390 Department of Neuropsychiatry ・・・・・・・・ 51 7100 Department of Life Science ・・・・・・・・ 113 0400 Department of Radiology ・・・・・・・・ 54 7200 Department of Advanced Medicine ・・・・・・・・ 116 0412 Department of Cardiovascular Surgery ・・・・・・・・ 56 7310 Division of Innovative Research ・・・・・・・・ 117 0415 Department of Thoracic Surgery ・・・・・・・・ 57 7320 Division of Vision Research for Environmental 0420 Department of General and Digestive Surgery ・・・・・・・・ 60 Health ・・・・・・・・ 120 0430 Department of Orthopedics Surgery ・・・・・・・・ 62 7340 Division of Anticipatory Molecular Food Science 0440 Department of Neurosurgery ・・・・・・・・ 65 and echnology ・・・・・・・・ 125 0450 Department of Plastic and Reconstructive 7350 Division of Systems Bioscience for Drug Surgery ・・・・・・・・ 67 Discovery Based on Intrinsically Disordered 0460 Department of Pediatric Surgery ・・・・・・・・ 69 Proteins ・・・・・・・・ 128 0470 Department of Ophthalmology ・・・・・・・・ 71 7400 Research Support Cente ・・・・・・・・ 129 Code DepaertmentPage Code Depaertment Page Himi Municipal Hospital 9100 Himi Municipal Hospital ・・・・・・・・ 131 Basic Medical Science 0100 Department of Anatomy Ⅰ Faculty Title Name Field of Specialization Professor HATTA Toshihisa developmental biology, neuroscience Professor HIGASHI Nobuaki macroscopic anatomy, embryology Associate Professor SAKATA Hiromi Developmental toxicology Senior Assistant Professor SHIMADA Hiroki Medical science of free radical Assistant Professor TSUKADA Tsuyoshi Developmental biology, Neuroscience, Neurosurgery Keywords of Research exo utero development, embryo, fetus, neurogenesis, cytokines, growth factors, hormones, stereology, ELISA, antioxidant, apoptosis, bcl-2, enzyme cytochemistry, electron microscopy, furanonaphthoquinone, free radical, immunohistochemistry, human macroscopic anatomy, mitochondria, NADH-quinone oxidoreductase, paraquat, reactive oxygen species, superoxide, scavenger, VDAC, anomaly of muscles and blood vessels Outline of Research 1. Studies on the feto-maternal signal transductions contributing to the fetal development via neuro-immune-endocrine network. 2. Cytochemical study of the cytotoxicity by reactive oxygen species. 3. Biological functions of VDAC family proteins. 4. Macroscopic studies on the variations of muscles and blodd vessels. 5. Comparative anatomical studies on the brain evolution Publications Originals 0100B001 Y.Yoshitomi,T.Ikeda,H.Saito,Y.Yoshitake,Y.Ishigaki,T.Hatta,N.Kato,H.Yonekura:JunB regulates angiogenesis and neurovascular parallel alignment in mouse embryonic skin, Jonal of Cell Science, 130:5;916-926, 2017. 0100B002 (Akai Takuya), Hatta Toshihisa, Shimada Hiroki, Mizuki Keiji, Kudo Nae, Hatta Taizo, Otani Hiroki:Extracranial outflow of particles solved in cerebrospinal fluid: Fluorescein injection study, Congenital Anomalies, 58:93-98, 2017. - 1 - 0110 Department of Anatomy Ⅱ Faculty Title Name Field of Specialization Professor HONMA Satoru gross anatomy Associate Professor ITO Tetsufumi neuroanatomy Senior Assistant Professor YASUTAKA Satoru gross anatomy Assistant Professor KOMINAMI Rieko neuroanatomy Keywords of Research arthrology, osteology, clinical anatomy, development, lymphatic vessels, muscle, innervation, nerve, ontogenesis, immunohistochemistry, electron microscopy, hippocampus, reconstruction, electron microscopy, vascularization, Neuroanatomy, FIB/SEM, BMI, gustatory Outline of Research Theme of researches 1)Human gross anatomy 2)Neural network of the basal ganglia 3)Circuit of gustatory in the central nervous system 4)Tissue reconstruction and vascularization of human hippocampus Publications Originals 0110B001 (Morita N), Ito T, Hasegawa RP, Murase K:Development of Functional Interlaminar Pathways in the Mouse Superior Colliculus Revealed by Optical Imaging with Axonal Labeling, Journal of Biosciences and Medicines, 5:8;11-35, 2017. 0110B002 (Mitsuhiro Matsuo), Satoru Honma, Takahiro Sonomura, Mitsuaki Yamazaki:Clinical anatomy of the cephalic vein for safe performance of venipuncture, JA Clinical Reports, 3:50, 2017. 0110B003 (Mamoru Uemura), Takamitsu Arakawa, Reiko Kominami, Satoru Honma, Akimichi Takemura:Identification of the optimal method for removing the capsule from the acinus of the rat's mandibular glands when preparing specimens for superficical morphology examination, Okajimas Folia Anat.Jpｎ., 94:3;109-113, 2017. - 2 - 0120 Department of Physiology Ⅰ Faculty Title Name Field of Specialization Professor KATO Nobuo Brain Science Senior Assistant Professor ONO Munenori Neuroscience Senior Assistant Professor TAJIMA Nobuyoshi molecular physiology Keywords of Research central nervous system, neurophysiology, electrophysiology, immunohistochemistry, field potential, propagating signal, horizontal propagation, oscillation, rat, guinea pig, slice preparation, in vitro, voltage-sensitive dye, subdivision, intracellular recording, intracellular staining, Neuroethology, Behavioral test battery, BK channel Outline of Research The brain is often regarded as a microcosmos, which contains more than a million neurons. Each neuron, however, is not a mere stardust. A single neuron integrates many inputs thereunto, so as to determine whether the output signal is released or not. Neurons are connected to each other by synapses to build neuron network, which underlies brain function. Our primary research interest is to elucidate, in molecular terms, how one or more neurons are able to regulate neuron excitability and synaptic efficiency. In particular, we are interested in studying in vitro how the versatile intracellular messenger calcium ion mediates a number of signals differentially, thereby achieving adequate regulation of synaptic efficiency and neuron excitability. Publications Originals 0120B001 Y.Yoshitomi,T.Ikeda,H.Saito,Y.Yoshitake,Y.Ishigaki,T.Hatta,N.Kato,H.Yonekura:JunB regulates angiogenesis and neurovascular parallel alignment in mouse embryonic skin, Jonal of Cell Science, 130:5;916-926, 2017. 0120B002 Xianwen Luo, Yuan Shui, Furong Wang, Ryo Yamamoto, Nobuo Kato:Impaired retention of depression-like behavior in a mouse model of Alzheimer's disease, IBRO Reports, 2:81-86, 2017. 0120B003 Munenori Ono, Deborah C Bishop, Douglas L Oliver:Identified GABAergic and Glutamatergic Neurons in the Mouse Inferior Colliculus Share Similar Response Properties, The Journal of Neuroscience, 37:37;8952-8964, 2017. Presentations at Conference International Conference (Presentations) 0120I001 Ono M, Bishop DC, Oliver DL:Neuronal Sensitivity to the Interaural Time Difference, The 2nd International Symposium on the Science of Mental Time, Nara, 2017.09. - 3 - 0130 Department of Physiology Ⅱ Faculty Title Name Field of Specialization SHIBAMOTO
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