Open Payments Report to Congress for Fiscal Year 2019
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By in Vivo's Biopharma, Medtech and Diagnostics Teams
invivo.pharmaintelligence.informa.com JANUARY 2018 Invol. 36 ❚ no. 01 Vivopharma intelligence ❚ informa 2018 OUTLOOK By In Vivo’s Biopharma, Medtech and Diagnostics Teams PAGE LEFT BLANK INTENTIONALLY invivo.pharmaintelligence.informa.com STRATEGIC INSIGHTS FOR LIFE SCIENCES DECISION-MAKERS CONTENTS ❚ In Vivo Pharma intelligence | January 2018 BIOPHARMA MEDTECH 2018 DIAGNOSTICS OUTLOOK 12 22 28 Biopharma 2018: Medtech 2018: Diagnostics 2018: Is There Still A Place For Pharma The Place For Innovation Steady Progress And In The New Health Care As Value-based Health Care The Big Get Bigger Economy? Gains Momentum MARK RATNER WILLIAM LOONEY ASHLEY YEO If the beginning of 2017 was marked 2018 will be a time of transition in health 2017 was a watershed year in many by doubts around whether and how care, when biopharma’s counterparts respects, politically, economically the FDA would act with respect to in adjacent industry segments scale up and commercially for many players complex diagnostics, we enter 2018 in a radical redesign of their traditional in the medtech field. Where will the feeling that slow-moving vessel may business models. Biopharma is not opportunities lie in 2018? Will finally be turning. moving as quickly, and it confronts a breakthrough medtech innovation still strategic dilemma on how to address the have a place among providers often prospect of a much more powerful set of riding on fumes when it comes to 36 rivals in the ongoing battle to own the budgets, and is it all as bad as some patient experience in medicine. would make out? Thirty-five Years Covering Health Care: The More Things Change… 30 PETER CHARLISH A Virtuous Cycle: What The The health care industry has come a Immuno-Oncology Revolution long way in the past 35 years, although Means For Other Disease Areas in some areas very little has changed. -
Infectious Diseases
2013 MEDICINES IN DEVELOPMENT REPORT Infectious Diseases A Report on Diseases Caused by Bacteria, Viruses, Fungi and Parasites PRESENTED BY AMERICA’S BIOPHARMACEUTICAL RESEARCH COMPANIES Biopharmaceutical Research Evolves Against Infectious Diseases with Nearly 400 Medicines and Vaccines in Testing Throughout history, infectious diseases hepatitis C that inhibits the enzyme have taken a devastating toll on the lives essential for viral replication. and well-being of people around the • An anti-malarial drug that has shown Medicines in Development world. Caused when pathogens such activity against Plasmodium falci- For Infectious Diseases as bacteria or viruses enter a body and parum malaria which is resistant to multiply, infectious diseases were the current treatments. Application leading cause of death in the United Submitted States until the 1920s. Today, vaccines • A potential new antibiotic to treat methicillin-resistant Staphylococcus Phase III and infectious disease treatments have proven to be effective treatments in aureus (MRSA). Phase II many cases, but infectious diseases still • A novel treatment that works by Phase I pose a very serious threat to patients. blocking the ability of the smallpox Recently, some infectious pathogens, virus to spread to other cells, thus 226 such as pseudomonas bacteria, have preventing it from causing disease. become resistant to available treatments. Infectious diseases may never be fully Diseases once considered conquered, eradicated. However, new knowledge, such as tuberculosis, have reemerged new technologies, and the continuing as a growing health threat. commitment of America’s biopharma- America’s biopharmaceutical research ceutical research companies can help companies are developing 394 medicines meet the continuing—and ever-changing and vaccines to combat the many threats —threat from infectious diseases. -
Fidelity® Extended Market Index Fund
Quarterly Holdings Report for Fidelity® Extended Market Index Fund May 31, 2021 SEI-QTLY-0721 1.816014.116 Schedule of Investments May 31, 2021 (Unaudited) Showing Percentage of Net Assets Common Stocks – 99.8% Shares Value Shares Value COMMUNICATION SERVICES – 6.0% CarGurus, Inc. Class A (a) 481,276 $ 13,581,609 Diversified Telecommunication Services – 0.5% Cars.com, Inc. (a) 356,794 5,212,760 Alaska Communication Systems Group, Inc. 306,734 $ 1,018,357 Creatd, Inc. (a) (b) 42,672 156,606 Anterix, Inc. (a) (b) 65,063 3,218,016 DHI Group, Inc. (a) 262,377 839,606 ATN International, Inc. 49,421 2,336,131 Eventbrite, Inc. (a) (b) 368,036 7,471,131 Bandwidth, Inc. (a) (b) 118,706 14,041,733 EverQuote, Inc. Class A (a) (b) 54,748 1,726,204 Cincinnati Bell, Inc. (a) 265,617 4,090,502 IAC (a) 439,438 70,077,178 Cogent Communications Group, Inc. (b) 226,643 17,134,211 Izea Worldwide, Inc. (a) 258,392 718,330 Consolidated Communications Holdings, Inc. (a) 325,131 3,043,226 Kubient, Inc. (b) 44,094 228,848 Cuentas, Inc. (a) (b) 48,265 108,596 Liberty TripAdvisor Holdings, Inc. (a) 380,876 1,812,970 Globalstar, Inc. (a) (b) 3,272,215 5,235,544 Match Group, Inc. (a) 1,417,570 203,251,187 IDT Corp. Class B (a) 96,642 2,789,088 MediaAlpha, Inc. Class A (b) 91,323 3,864,789 Iridium Communications, Inc. (a) 621,382 23,743,006 Pinterest, Inc. Class A (a) 2,805,904 183,225,531 Liberty Global PLC: Professional Diversity Network, Inc. -
Interactive Television for Young Children
Interactive Television for Young Children: Developing Design Principles Ana Vitoria Joly Hulshof A thesis submitted in partial fulfilment of the requirements of the University of Brighton for the degree of Doctor of Philosophy September 2010 University of Brighton Abstract The research reported in this thesis investigates preschoolers‟ interactions with interactive television applications. The study involved the development of an electronic programme guide prototype and the empirical evaluation thereof. There were three main aims. The first aim was to analyse children‟s interactions and illustrate them in a framework to further understanding of the way preschoolers interact with the television. The second aim was to contribute design principles for preschool interactive television and the third aim was to refine methods and add to the knowledge of design and evaluation techniques involving young children. This research, which involved design and evaluation phases, was carried out with children in Brazil and in the United Kingdom aged between three and four. Children participated actively as informants and were asked for input at various stages of the project. Their participation during design activities and evaluation sessions was crucial to the constitution of the framework, the development of design principles and the refinement of methods for working with preschoolers. The results revealed that young children‟s interactions with interactive television are influenced by: the children‟s age, motor skills, country context, media and device use and knowledge. These factors along with the input device used for interaction and characteristics of the interactive television application determine the number of accomplishable tasks, the time taken to accomplish the tasks, the complexity of the tasks that can be accomplished, the hints and assistance as well as interactions needed to accomplish the tasks. -
West Virginia Broadband Enhance Council 2020 Annual Report
2020 West Virginia Broadband Enhancement Council 2020 ANNUAL REPORT TO THE WEST VIRGINIA LEGISLATURE Table of Contents 1. Executive Summary ............................................................................................................................... 1 2. Existing, Continuing and New Initiatives ............................................................................................... 2 3. Broadband Mapping ............................................................................................................................. 4 Key Components of the Interactive Mapping System .................................................................. 4 Broadband Advertised Speed Ranges Interactive Map ................................................................ 5 Broadband Development Hub ...................................................................................................... 6 Public Wi-Fi Map ........................................................................................................................... 6 Public Project Development ......................................................................................................... 7 Speed Tiers by County ................................................................................................................... 8 Speed Tiers Statewide ................................................................................................................... 8 Providers Statewide ..................................................................................................................... -
Monday, April 22 Chicago Bears Room Chicago Bulls Room Chicago Cubs Room Merck KLOX Technologies Immune Design Leading Biote
As of 4/23/2013 Schedule subject to change Monday, Chicago Bears Room Chicago Bulls Room Chicago Cubs Room April 22 Merck KLOX Technologies Immune Design 1:00 PM Leading Biotech/Big Pharma Medical Devices Vaccines Eli Lilly NewSouth Innovations Syntiron 1:15 PM Leading Biotech/Big Pharma University/Academia Vaccines Amgen Radius Health BioCrea 1:30 PM Leading Biotech/Big Pharma Musculoskeletal Neurology/CNS Nat. Inst. of Neurological Dis. & Stroke Cytokinetics Xenon Pharmaceuticals 1:45 PM Neurology/CNS Musculoskeletal Neurology/CNS Curis OrgaNext Research BV Trigemina 2:00 PM Oncology Regenerative Medicine Neurology/CNS Verastem Flexion Therapeutics Neurocrine Biosciences 2:15 PM Oncology Musculoskeletal Hormone Therapy/CNS Michael J. Fox Foundation Antisense Pharma GmbH Versartis 2:30 PM Non-profit/Patient Advocacy Oncology Hormone Therapy Takeda Pharmaceutical Company TBD KODE Biotech 2:45 PM Leading Biotech/Big Pharma Drug Delivery Resverlogix Corp. Advaxis Q Chip 3:00 PM Cardiovascular Disease Oncology Drug Delivery Grünenthal GmbH Array BioPharma 3:15 PM Neurology/CNS Oncology/Drug Discovery Discovery Labs Mersana Therapeutics 3:30 PM Drug Delivery/Pulmonary Oncology Bayer HealthCare Igenica 3:45 PM Leading Biotech/Big Pharma Oncology Presentations are open to all Convention attendees and are located outside the main entrance of the BIO Business Forum As of 4/23/2013 - Schedule subject to change Tuesday, Chicago Bears Room Chicago Bulls Room Chicago Cubs Room Chicago Blackhawks Room April 23 Pfizer 8:00 AM Leading Biotech/Big Pharma -
February 11-12, 2013 the Waldorf Astoria New York
February 11-12, 2013 The Waldorf Astoria New York 15th ANNU AL EVENT Now in its fifteenth year, the BIO CEO & Investor Conference is the largest independent investor conference focused on leading publicly-traded biotech companies. The meeting provides a neutral forum where institutional investors, industry analysts, and senior biotechnology executives have the opportunity to shape the future investment landscape of the biotechnology industry. Reasons Top 10 to attend 1 Present your company story to an audience of targeted investors. 2 Hear the Washington perspective on the Affordable Care Act, debt ceiling, and other timely policy developments affecting the industry. 3 Evaluate fresh investment opportunities including compatible, complementary and competitive companies. 4 Learn about the hottest clinical developments and industry catalysts by attending the conference’s therapeutic workshops and business roundtables. 5 Attend fireside chats with CEOs who will share their recent company successes, what keeps the C-suite up at night, and where the industry’s leading companies are headed in 2013. 6 Gain access to BIO’s 1x1 Partnering System for scouting potential deal partners and optimizing your time at the event. 7 Access presentations from more than 140 established public and private biotech companies and non-profit funding organizations, including many you won’t hear from at other investor conferences. 8 Get the pulse on the current and proposed investment trends in biotechnology. 9 Network with peers, investors and potential partners attending the conference. 10 It’s the first NYC biotech conference of the year, kicking off a week of key industry events that you don’t want to miss. -
Internet Pricing and the History of Communications
Internet pricing and the history of communications Andrew Odlyzko AT&T Labs - Research [email protected] http://www.research.att.com/ amo Revised version, February 8, 2001. Abstract There are repeating patterns in the histories of communication technologies, including ordinary mail, the telegraph, the telephone, and the Internet. In particular, the typical story for each service is that quality rises, prices decrease, and usage increases to produce increased total revenues. At the same time, prices become simpler. The historical analogies of this paper suggest that the Internet will evolve in a similar way, towards simplicity. The schemes that aim to provide differentiated service levels and sophisticated pricing schemes are unlikely to be widely adopted. Price and quality differentiation are valuable tools that can provide higher revenues and increase utilization efficiency of a network, and thus in general increase social welfare. Such measures, most noticeable in airline pricing, are spreading to many services and products, especially high-tech ones. However, it appears that as communication services become less expensive and are used more fre- quently, those arguments lose out to customers’ desire for simplicity. In practice, user preferences express themselves through willingness to pay more for simple pricing plans. In addition, there is a strong “threshhold” effect to usage-sensitive billing. Even tiny charges based on utilization decrease usage substantially. In a rapidly growing market, it is in the service providers’ interest to encourage usage, and that argues for simple, preferably flat rate, pricing. Histori- cal evidence suggests that when service costs decrease, such arguments prevail over the need to operate a network at high utilization levels and to extract the highest possible revenues. -
Pastor Tom Gable and Pastor Kathryn Gulbranson
The four weeks leading up to Christmas Day are called Advent—meaning coming or arrival. It’s a season of waiting and preparing before the birth of Jesus, a time to prepare our hearts and our homes for the arrival of the baby Jesus. This time of waiting invites us to take time to slow down and reflect. To help facilitate that waiting, preparing, and reflecting, we’re offering Holden Evening Prayer at 6:30pm on Wednesdays—the 2nd, 9th, and 16thon Zoom (Meeting ID: 4159243782). This is in addition to our regular Sunday morning worship on Zoom at 9:30am, our YouTube Worship Videos and twice weekly Devotions. Please Join Us! And to celebrate the Birth of Our Savior—Christmas, we are offering two services: o 12/24 at 4 pm—Christmas Eve Family Service—joining together with Elim Lutheran Church in Petaluma and led by Pastor Tom Gable and Pastor Kathryn Gulbranson. This will be live, on Zoom—Meeting ID: 4159243782. o 12/24 at 6 pm—Christmas Eve Service of Lessons and Carols. This worship will be televised on our local community access cable stations: Channel 26 (Comcast) and Channel 99 (AT&T U-verse), livestreamed at www.marintv.org and shown on our Marin Lutheran YouTube https://www.youtube.com/channel/UClEvlmnS72YKEIgw6laMRwA. Please make every effort to invite you neighbors, friends and relatives in the area and around the country to join us for one or both of these services. They will be special times to celebrate the birth of our Savior who brings hope and joy into our world! I close with a prayer: As we wait for the birth of Jesus, we pause and think about what we want this season to be: a season of hope, a season of peace, a season of joy, a season of love, a season of family togetherness, a season of reflection. -
Fidelity® Total Market Index Fund
Quarterly Holdings Report for Fidelity® Total Market Index Fund May 31, 2021 STI-QTLY-0721 1.816022.116 Schedule of Investments May 31, 2021 (Unaudited) Showing Percentage of Net Assets Common Stocks – 99.3% Shares Value Shares Value COMMUNICATION SERVICES – 10.1% World Wrestling Entertainment, Inc. Class A (b) 76,178 $ 4,253,780 Diversified Telecommunication Services – 1.1% Zynga, Inc. (a) 1,573,367 17,055,298 Alaska Communication Systems Group, Inc. 95,774 $ 317,970 1,211,987,366 Anterix, Inc. (a) (b) 16,962 838,941 Interactive Media & Services – 5.6% AT&T, Inc. 11,060,871 325,521,434 Alphabet, Inc.: ATN International, Inc. 17,036 805,292 Class A (a) 466,301 1,099,001,512 Bandwidth, Inc. (a) (b) 34,033 4,025,764 Class C (a) 446,972 1,077,899,796 Cincinnati Bell, Inc. (a) 84,225 1,297,065 ANGI Homeservices, Inc. Class A (a) 120,975 1,715,426 Cogent Communications Group, Inc. (b) 66,520 5,028,912 Autoweb, Inc. (a) (b) 6,653 19,028 Consolidated Communications Holdings, Inc. (a) 110,609 1,035,300 Bumble, Inc. 77,109 3,679,641 Globalstar, Inc. (a) (b) 1,067,098 1,707,357 CarGurus, Inc. Class A (a) 136,717 3,858,154 IDT Corp. Class B (a) (b) 31,682 914,343 Cars.com, Inc. (a) 110,752 1,618,087 Iridium Communications, Inc. (a) 186,035 7,108,397 DHI Group, Inc. (a) (b) 99,689 319,005 Liberty Global PLC: Eventbrite, Inc. (a) 114,588 2,326,136 Class A (a) 196,087 5,355,136 EverQuote, Inc. -
Prodigy Service Is T He Online Net Over 1 Miluon Work That Connects New Friends
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The Weekly Shot Biotech Issue a Weekly Summary of Healthcare Industry Valuation and Near-Term Catalysts June 17, 2010
Small Cap The Weekly Shot Biotech Issue June 17, 2010 A weekly summary of healthcare industry valuation and near-term catalysts The Weekly Shot: Overview and Comment - Small Cap Biotechnology Next week's sector highlights include LGND’s Thursday analyst event at the Eventi - Pharmaceuticals and Large Cap Biotech Hotel in NYC. The company on 6/15 announced updated 2010 revenue guidance of approx $25M, op ex of approx $30M, and expects to finish the year with $30M - Generics and Specialty Pharmaceuticals in cash (vs approx $43M as of 1Q10). Management will likely focus on partner GSK’s progress with add’l trials of Promacta (for ITP), which could potentially expand the drug’s label to Hep C, AML, and MDS (LGND receives <10% royalty from GSK). Investors should focus on pipeline plans following LGND’s opportunistic 2008/09 M&A activity. Key pipeline programs include LGD-4033 (ph.I, SARM candidate from PCOP) and RG7348, partnered with Roche (ph.I, Hep C candidate from MBRX). We do not expect major data announcements at the event. FDA’s Pediatric Drugs Advisory Committee will meet Monday to discuss pediatric safety reviews of multiple approved drugs, including Kogenate, Casodex, Apidra, NovoLog, Arimidex, Desmopressin, Prevacid, Nexium, Aciphex, Priolex, OraVerse, Zemuron, and Suprane . While important from a public safety perspective, we do not anticipate regulatory activity to be announced. Brian Lian, Ph.D. Small caps biotechs rebounded mid-week as elevated volatility continued across 212.500.6646 [email protected] the broader market. Investors are struggling to balance economic data supporting a modest recovery against concerns on EU debt loads, financial reform legislation, and aggressive govt rhetoric on BP’s oil spill.