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PDF Output of CLIC (Clustering by Inferred Co-Expression) PDF Output of CLIC (clustering by inferred co-expression) Dataset: Num of genes in input gene set: 7 Total number of genes: 16493 CLIC PDF output has three sections: 1) Overview of Co-Expression Modules (CEMs) Heatmap shows pairwise correlations between all genes in the input query gene set. Red lines shows the partition of input genes into CEMs, ordered by CEM strength. Each row shows one gene, and the brightness of squares indicates its correlations with other genes. Gene symbols are shown at left side and on the top of the heatmap. 2) Details of each CEM and its expansion CEM+ Top panel shows the posterior selection probability (dataset weights) for top GEO series datasets. Bottom panel shows the CEM genes (blue rows) as well as expanded CEM+ genes (green rows). Each column is one GEO series dataset, sorted by their posterior probability of being selected. The brightness of squares indicates the gene's correlations with CEM genes in the corresponding dataset. CEM+ includes genes that co-express with CEM genes in high-weight datasets, measured by LLR score. 3) Details of each GEO series dataset and its expression profile: Top panel shows the detailed information (e.g. title, summary) for the GEO series dataset. Bottom panel shows the background distribution and the expression profile for CEM genes in this dataset. Overview of Co-Expression Modules (CEMs) with Dataset Weighting Scale of average Pearson correlations Num of Genes in Query Geneset: 7. Num of CEMs: 1. 0.0 0.2 0.4 0.6 0.8 1.0 Cks1b Skp2 Ccne1 Cul1 Skp1a Cdkn1b Cdk2 Cks1b Skp2 Ccne1 CEM 1 (179 datasets) Cul1 Skp1a Cdkn1b Singletons Cdk2 Symbol Num ofCEMGenes:5.Predicted1174.SelectedDatasets:179.Strength:0.9 CEM 1,Geneset"[C]p27-cyclinE-Cdk2-UbiquitinE3ligase",Page1 Rad51ap1 Ranbp1 Shcbp1 Wdhd1 Cenph Kpna2 Cenpk Ercc6l Ccna2 Cdc45 Trip13 Kif20a Rad51 Cdca5 Ccne1 Cks1b Spc24 Skp1a Fbxo5 Fignl1 Aurkb Mcm2 Mcm7 Mcm4 Mcm5 Gins1 Prim1 Asf1b Tfdp1 Uhrf1 Rrm1 Birc5 Bub1 Rpa2 Cdk1 Cdc6 Pcna Hells Exo1 Skp2 Tipin Fen1 Ezh2 Orc6 Melk Rfc4 Rfc5 Cul1 Lig1 Tk1 0.0 1.0 GSE13693 [9] GSE30160 [6] GSE20954 [14] Only showingfirst200datasets-Seetxtoutputforfulldetails. GSE16679 [8] GSE12465 [14] GSE7705 [10] GSE6837 [8] GSE6998 [32] GSE7875 [16] GSE57543 [6] GSE16874 [12] GSE18135 [18] GSE28237 [6] GSE48790 [8] GSE13874 [14] GSE13873 [27] GSE46185 [6] GSE26616 [6] GSE12464 [23] GSE27605 [8] GSE10176 [6] GSE51483 [45] GSE46797 [6] GSE48204 [6] GSE11220 [44] GSE28389 [20] GSE7430 [12] GSE31598 [12] GSE39233 [40] GSE51628 [15] GSE22180 [60] GSE17316 [12] GSE38831 [7] GSE11356 [9] GSE6689 [12] GSE15541 [12] GSE12078 [8] GSE11222 [42] GSE51385 [8] GSE12498 [12] GSE15161 [26] GSE32078 [12] GSE32277 [33] GSE13692 [8] GSE46970 [15] GSE6933 [15] GSE21278 [48] GSE21841 [18] GSE7863 [16] GSE15872 [18] GSE22005 [23] GSE21606 [6] GSE45619 [6] GSE7897 [60] GSE24813 [10] GSE12454 [13] GSE24210 [16] GSE27786 [20] GSE20398 [30] GSE17509 [57] GSE33471 [12] GSE24789 [9] GSE44162 [6] GSE16925 [15] GSE10525 [18] GSE9763 [20] GSE7404 [144] GSE51243 [7] GSE32598 [11] GSE30962 [16] GSE15580 [14] GSE38693 [8] GSE42135 [42] GSE10344 [6] GSE14406 [54] GSE1479 [36] GSE21299 [12] GSE4739 [19] GSE24512 [29] GSE25637 [9] GSE29632 [42] GSE7784 [12] GSE8836 [56] GSE9287 [8] GSE9297 [27] GSE9146 [27] GSE15303 [11] GSE5976 [12] GSE30485 [15] GSE46090 [12] GSE9247 [15] GSE8960 [18] GSE15267 [8] GSE39034 [9] GSE51883 [30] GSE51804 [10] GSE52474 [154] GSE39449 [6] GSE19657 [21] GSE48382 [10] GSE28621 [21] GSE23040 [6] GSE15069 [15] GSE33308 [10] GSE15624 [12] GSE28457 [24] GSE6875 [8] GSE23845 [15] GSE21224 [16] GSE16110 [16] GSE21716 [28] GSE35106 [9] GSE32386 [13] GSE4818 [21] GSE46600 [44] GSE14769 [24] GSE35593 [6] GSE21063 [24] GSE46091 [8] GSE27848 [16] GSE35825 [9] GSE9804 [9] GSE51608 [6] GSE8025 [21] GSE15324 [8] GSE7020 [8] GSE7759 [112] GSE10913 [6] GSE25640 [12] GSE39469 [6] GSE6850 [10] GSE21905 [6] GSE27379 [6] GSE40513 [6] GSE13227 [6] GSE31028 [6] GSE18534 [15] GSE44260 [10] GSE12518 [6] GSE21379 [10] GSE7948 [13] GSE32963 [6] GSE38304 [8] GSE35998 [20] GSE43145 [12] GSE31313 [22] GSE5671 [18] GSE38257 [14] GSE24243 [6] GSE11870 [6] GSE6259 [21] GSE28417 [12] GSE13306 [17] GSE11186 [33] CEM+ CEM GSE11201 [18] GSE5334 [19] GSE35366 [78] GSE4260 [6] GSE34839 [6] GSE51075 [12] 0.0 GSE4230 [8] GSE35785 [10] GSE14012 [24] Scale ofaveragePearsoncorrelations GSE20302 [12] GSE25737 [6] GSE42601 [6] GSE38837 [6] GSE46209 [21] GSE25423 [10] 0.2 GSE40856 [8] GSE29681 [32] GSE15155 [12] GSE19885 [9] GSE8034 [17] GSE9725 [16] GSE45051 [18] GSE24628 [16] GSE30164 [23] 0.4 GSE46606 [30] GSE21309 [9] GSE14308 [12] GSE13493 [6] GSE54653 [6] GSE18281 [33] GSE23600 [10] GSE13149 [25] GSE49346 [6] 0.6 GSE40230 [15] GSE14698 [12] GSE39621 [51] GSE43197 [27] GSE8512 [207] GSE18136 [12] GSE4142 [14] GSE51932 [8] GSE3861 [6] 0.8 GSE6957 [12] GSE50813 [24] GSE14753 [6] GSE36530 [6] Score 142.90 143.03 143.58 143.62 144.14 144.49 144.75 145.41 146.56 146.57 146.94 147.13 147.15 147.22 148.34 148.43 148.69 148.79 148.80 149.25 149.41 149.49 149.82 150.25 150.26 152.06 152.91 153.33 153.33 153.43 153.92 154.46 155.29 155.62 157.27 159.44 159.65 161.39 161.68 161.80 162.39 164.08 165.09 165.09 165.47 1.0 Notes Symbol Num ofCEMGenes:5.Predicted1174.SelectedDatasets:179.Strength:0.9 CEM 1,Geneset"[C]p27-cyclinE-Cdk2-UbiquitinE3ligase",Page2 Arhgap11a BC055324 Mis18bp1 Hnrnpab Ncapd2 Nup107 Topbp1 Chaf1b Dnajc9 Zwilch Bub1b Apitd1 Ncapg Ncaph Nup85 Ube2c Ccne2 Cdc20 Rfwd3 Gmnn Mcm6 Aurka Hirip3 Brca1 Gins2 Atad2 Atad5 Cenpi Phf5a Spdl1 Sgol1 Pola1 Eme1 Cse1l Lsm3 Rrm2 Rpa3 Kif11 Ppil1 Cks2 Tpx2 Orc1 Dbf4 Hat1 Rfc3 Pole Plk4 Plk1 Dhfr Pbk 0.0 1.0 GSE13693 [9] GSE30160 [6] GSE20954 [14] Only showingfirst200datasets-Seetxtoutputforfulldetails. GSE16679 [8] GSE12465 [14] GSE7705 [10] GSE6837 [8] GSE6998 [32] GSE7875 [16] GSE57543 [6] GSE16874 [12] GSE18135 [18] GSE28237 [6] GSE48790 [8] GSE13874 [14] GSE13873 [27] GSE46185 [6] GSE26616 [6] GSE12464 [23] GSE27605 [8] GSE10176 [6] GSE51483 [45] GSE46797 [6] GSE48204 [6] GSE11220 [44] GSE28389 [20] GSE7430 [12] GSE31598 [12] GSE39233 [40] GSE51628 [15] GSE22180 [60] GSE17316 [12] GSE38831 [7] GSE11356 [9] GSE6689 [12] GSE15541 [12] GSE12078 [8] GSE11222 [42] GSE51385 [8] GSE12498 [12] GSE15161 [26] GSE32078 [12] GSE32277 [33] GSE13692 [8] GSE46970 [15] GSE6933 [15] GSE21278 [48] GSE21841 [18] GSE7863 [16] GSE15872 [18] GSE22005 [23] GSE21606 [6] GSE45619 [6] GSE7897 [60] GSE24813 [10] GSE12454 [13] GSE24210 [16] GSE27786 [20] GSE20398 [30] GSE17509 [57] GSE33471 [12] GSE24789 [9] GSE44162 [6] GSE16925 [15] GSE10525 [18] GSE9763 [20] GSE7404 [144] GSE51243 [7] GSE32598 [11] GSE30962 [16] GSE15580 [14] GSE38693 [8] GSE42135 [42] GSE10344 [6] GSE14406 [54] GSE1479 [36] GSE21299 [12] GSE4739 [19] GSE24512 [29] GSE25637 [9] GSE29632 [42] GSE7784 [12] GSE8836 [56] GSE9287 [8] GSE9297 [27] GSE9146 [27] GSE15303 [11] GSE5976 [12] GSE30485 [15] GSE46090 [12] GSE9247 [15] GSE8960 [18] GSE15267 [8] GSE39034 [9] GSE51883 [30] GSE51804 [10] GSE52474 [154] GSE39449 [6] GSE19657 [21] GSE48382 [10] GSE28621 [21] GSE23040 [6] GSE15069 [15] GSE33308 [10] GSE15624 [12] GSE28457 [24] GSE6875 [8] GSE23845 [15] GSE21224 [16] GSE16110 [16] GSE21716 [28] GSE35106 [9] GSE32386 [13] GSE4818 [21] GSE46600 [44] GSE14769 [24] GSE35593 [6] GSE21063 [24] GSE46091 [8] GSE27848 [16] GSE35825 [9] GSE9804 [9] GSE51608 [6] GSE8025 [21] GSE15324 [8] GSE7020 [8] GSE7759 [112] GSE10913 [6] GSE25640 [12] GSE39469 [6] GSE6850 [10] GSE21905 [6] GSE27379 [6] GSE40513 [6] GSE13227 [6] GSE31028 [6] GSE18534 [15] GSE44260 [10] GSE12518 [6] GSE21379 [10] GSE7948 [13] GSE32963 [6] GSE38304 [8] GSE35998 [20] GSE43145 [12] GSE31313 [22] GSE5671 [18] GSE38257 [14] GSE24243 [6] GSE11870 [6] GSE6259 [21] GSE28417 [12] GSE13306 [17] GSE11186 [33] CEM+ CEM GSE11201 [18] GSE5334 [19] GSE35366 [78] GSE4260 [6] GSE34839 [6] GSE51075 [12] 0.0 GSE4230 [8] GSE35785 [10] GSE14012 [24] Scale ofaveragePearsoncorrelations GSE20302 [12] GSE25737 [6] GSE42601 [6] GSE38837 [6] GSE46209 [21] GSE25423 [10] 0.2 GSE40856 [8] GSE29681 [32] GSE15155 [12] GSE19885 [9] GSE8034 [17] GSE9725 [16] GSE45051 [18] GSE24628 [16] GSE30164 [23] 0.4 GSE46606 [30] GSE21309 [9] GSE14308 [12] GSE13493 [6] GSE54653 [6] GSE18281 [33] GSE23600 [10] GSE13149 [25] GSE49346 [6] 0.6 GSE40230 [15] GSE14698 [12] GSE39621 [51] GSE43197 [27] GSE8512 [207] GSE18136 [12] GSE4142 [14] GSE51932 [8] GSE3861 [6] 0.8 GSE6957 [12] GSE50813 [24] GSE14753 [6] GSE36530 [6] Score 128.75 128.95 129.02 129.06 129.08 129.20 129.41 129.81 130.08 130.30 130.35 131.59 132.02 132.94 133.55 133.58 133.77 133.96 134.26 134.35 134.40 134.66 134.85 135.26 135.50 135.62 136.08 136.40 136.57 136.64 137.50 137.51 137.62 137.76 137.95 138.25 138.27 138.76 139.55 139.59 140.18 140.37 140.50 140.69 140.72 141.95 141.99 142.30 142.35 142.72 1.0 Notes 4930579G24Rik Symbol Num ofCEMGenes:5.Predicted1174.SelectedDatasets:179.Strength:0.9 CEM 1,Geneset"[C]p27-cyclinE-Cdk2-UbiquitinE3ligase",Page3 Racgap1 Suv39h1 Suv39h2 Mms22l Rbmxl1 Nup133 Nup155 Snrpa1 Hmgb3 Nudt21 Ruvbl1 Cenpw Incenp Dnmt1 Chtf18 Cenpn Lrrc40 Ccnb2 Nup93 Cenpe Rqcd1 Pbdc1 Spag5 Actl6a Dpy30 Cdca7 Cdca8 Ddx39 Esco2 Mybl2 Alyref Sf3a3 Espl1 Pole2 Gsg2 Uba2 Kif22 Cdc7 Rcc1 Ska3 Oip5 Nuf2 Ccnf Ect2 E2f7 Dis3 Blm Ttf2 Stil 0.0 1.0 GSE13693 [9] GSE30160 [6] GSE20954 [14] Only showingfirst200datasets-Seetxtoutputforfulldetails. GSE16679 [8] GSE12465 [14] GSE7705 [10] GSE6837 [8] GSE6998 [32] GSE7875 [16] GSE57543 [6] GSE16874 [12] GSE18135 [18] GSE28237 [6] GSE48790 [8] GSE13874 [14] GSE13873 [27] GSE46185 [6] GSE26616 [6] GSE12464 [23] GSE27605 [8] GSE10176
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