Corey Lane Bretz | Curriculum Vitae, January 25, 2017 Corey

Total Page:16

File Type:pdf, Size:1020Kb

Corey Lane Bretz | Curriculum Vitae, January 25, 2017 Corey Corey Lane Bretz Doctoral candidate, Louisiana State University Department of Biological Sciences 688 Life Sciences Building Phone: (225) 439-9601 Email: [email protected] EDUCATION/TRAINING Louisiana State University: Ph.D. in Biology (anticipated August 2017) Laboratory of Dr. Joomyeong Kim Louisiana State University: B.S. in Biology and minor in Chemistry (May 2013) Awarded University Medal for Highest Academic Achievement PROFESSIONAL POSITIONS Research (LSU) – May 2012 to present • Graduate teaching assistantship • LSU-HHMI undergraduate research fellow Teaching (LSU) – August 2013 to present • Biology Lab for Science majors • Microbiology laboratory • Principles of Genetics Student Affairs (LSU) – Summer 2014 and summer 2015 • LSU-HHMI Undergraduate Research Program assistant coordinator Supplemental Instruction Leader (LSU) – (August 2011 to May 2013) • Organic chemistry I & II Animal Husbandry (LSU - DLAM) – (April 2010 to August 2010) • Student worker: routine laboratory animal husbandry PUBLICATIONS 1. C.L. Bretz, I.M. Langohr, and J. Kim. (Submitted Dec 2016) Epigenetic response of imprinted domains during carcinogenesis. Clinical Epigenetics, under review. 2. C.L. Bretz, I.M. Langohr, S. Lee, and J. Kim. (2015) Epigenetic instability at imprinting control regions in a KrasG12D-induced T-cell neoplasm. Epigenetics. PMID: 26507119 3. J. Kim, C.L. Bretz, S. Lee. (2015) Epigenetic instability of imprinted genes in human cancers. Nucleic Acids Res. PMID: 26338779 Corey Lane Bretz | Curriculum Vitae, January 25, 2017 HONORS AND AWARDS • Spring 2015 Graduate student travel award – LSU ($500) • 2013- 2017 Graduate training enrichment award ($5,000/yr) • Spring 2013 LSU university medalist – summa cum laude • Spring 2013 CASE awardee (3rd place) – UF-HHMI ($300) • Summer 2012 Summer undergraduate research fellow – LSU-HHMI ($4,000) • 2011 - 2013 Bingham Cushman Stewart scholarship ($350/semester) • 2009 - 2013 Chancellor’s honor roll PRESENTATIONS 2012 • Behavioral and developmental abnormalities in Peg3 conditional knockout mice – Summer Undergraduate Research Forum (LSU) 2013 • Behavioral and developmental abnormalities in Peg3 conditional knockout mice – Creativity in the Arts & Sciences Event (UF) 2014 • Epigenetic instability of imprinting control regions in K-rasG12D-induced tumors – BioGrads Symposium (LSU) 2015 • Epigenetic instability of imprinting control regions in precursor T-cell lymphoblastic lymphoma – DNA Methylation (Z1) - Keystone Symposia (Colorado) GRANTS 1. Paternally expressed gene 3 as a suppressor of tumor formation and progression. (2013) PA-11- 111 Ruth L. Kirschtein National Research Service Awards for Individual Predoctoral Fellows (Parent F31). Not funded. SERVICE AND OUTREACH • 2013 – present Volunteer – Bluebonnet bird monitoring • Summer 2013 Field research assistant – North American breeding bird survey • Summer 2013 Field research assistant – Bird distribution and abundance study • 2010-2011 Field research assistant – Dolphin population ecology study Corey Lane Bretz | Curriculum Vitae, January 25, 2017 REFERENCES 1. Dr. Joomyeong Kim (Major professor) Russell Thompson, Jr. Family Professor Department of Biological Sciences Louisiana State University, Baton Rouge Email: [email protected] Phone: (225) 578-7692 2. Dr. Ingeborg Langohr (collaborator) Associate Professor Department of Pathobiological Sciences School of Veterinary Medicine Louisiana State University, Baton Rouge Email: [email protected] Phone: (225) 578-9722 3. Dr. Mark A. Batzer (committee member) LSU System Boyd Professor Department of Biological Sciences Louisiana State University, Baton Rouge Email: [email protected] Phone: (225) 578-7102 4. Dr. David Donze (committee member) Professor Department of Biological Sciences Louisiana State University, Baton Rouge Email: [email protected] Phone: (225) 578-7391 Corey Lane Bretz | Curriculum Vitae, January 25, 2017 .
Recommended publications
  • Molecular Characterization of the T(4;9)12Gso Mutation and Analysis of the Associated Fitness, Skeletal, and Lymphoproliferative Phenotypes
    University of Tennessee, Knoxville TRACE: Tennessee Research and Creative Exchange Doctoral Dissertations Graduate School 8-2002 Molecular Characterization of the T(4;9)12Gso Mutation and Analysis of the Associated Fitness, Skeletal, and Lymphoproliferative Phenotypes Laura Ray Chittenden University of Tennessee - Knoxville Follow this and additional works at: https://trace.tennessee.edu/utk_graddiss Part of the Biomedical Engineering and Bioengineering Commons Recommended Citation Chittenden, Laura Ray, "Molecular Characterization of the T(4;9)12Gso Mutation and Analysis of the Associated Fitness, Skeletal, and Lymphoproliferative Phenotypes. " PhD diss., University of Tennessee, 2002. https://trace.tennessee.edu/utk_graddiss/2105 This Dissertation is brought to you for free and open access by the Graduate School at TRACE: Tennessee Research and Creative Exchange. It has been accepted for inclusion in Doctoral Dissertations by an authorized administrator of TRACE: Tennessee Research and Creative Exchange. For more information, please contact [email protected]. To the Graduate Council: I am submitting herewith a dissertation written by Laura Ray Chittenden entitled "Molecular Characterization of the T(4;9)12Gso Mutation and Analysis of the Associated Fitness, Skeletal, and Lymphoproliferative Phenotypes." I have examined the final electronic copy of this dissertation for form and content and recommend that it be accepted in partial fulfillment of the requirements for the degree of Doctor of Philosophy, with a major in Biomedical Engineering.
    [Show full text]
  • Phylogenetic and Epigenetic Footprinting of the Putative Enhancers of the Peg3 Domain
    RESEARCH ARTICLE Phylogenetic and Epigenetic Footprinting of the Putative Enhancers of the Peg3 Domain Joomyeong Kim*,AnYe Department of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803, United States of America * [email protected] Abstract The Peg3 (Paternally Expressed Gene 3) imprinted domain is predicted to be regulated through a large number of evolutionarily conserved regions (ECRs) that are localized within a11111 its middle 200-kb region. In the current study, we characterized these potential cis-regula- tory regions using phylogenetic and epigenetic approaches. According to the results, the majority of these ECRs are potential enhancers for the transcription of the Peg3 domain. Also, these potential enhancers can be divided into two groups based on their histone modi- fication and DNA methylation patterns: ubiquitous and tissue-specific enhancers. Phyloge- netic and bioinformatic analyses further revealed that several cis-regulatory motifs are OPEN ACCESS frequently associated with the ECRs, such as the E box, PITX2, NF-κB and RFX1 motifs. A series of subsequent ChIP experiments demonstrated that the trans factor MYOD indeed Citation: Kim J, Ye A (2016) Phylogenetic and Epigenetic Footprinting of the Putative Enhancers of binds to the E box of several ECRs, further suggesting that MYOD may play significant the Peg3 Domain. PLoS ONE 11(4): e0154216. roles in the transcriptional control of the Peg3 domain. Overall, the current study identifies, doi:10.1371/journal.pone.0154216 for the first time, a set of cis-regulatory motifs and corresponding trans factors that may be Editor: Martina Stromvik, McGill University, CANADA critical for the transcriptional regulation of the Peg3 domain.
    [Show full text]
  • Epigenetic Instability of Imprinted Genes in Human Cancers Joomyeong Kim*, Corey L
    Published online 3 September 2015 Nucleic Acids Research, 2015, Vol. 43, No. 22 10689–10699 doi: 10.1093/nar/gkv867 Epigenetic instability of imprinted genes in human cancers Joomyeong Kim*, Corey L. Bretz and Suman Lee Department of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803, USA Received May 10, 2015; Revised August 14, 2015; Accepted August 17, 2015 ABSTRACT (2,3). Among the 100 imprinted genes found in the hu- man genome, the well-known examples include H19, IGF2 Many imprinted genes are often epigenetically af- (Insulin-like growth factor 2), IGF2R (IGF2 receptor), fected in human cancers due to their functional link- GNAS (stimulatory GTPase ␣), GRB10 (Growth factor- age to insulin and insulin-like growth factor signal- bound protein 10), MEST (Mesoderm-Specific Transcript) ing pathways. Thus, the current study systemati- and PEG3 (Paternally Expressed Gene 3) (3). cally characterized the epigenetic instability of im- Imprinted genes are also clustered in specific chromoso- printed genes in multiple human cancers. First, the mal domains, size-ranging from 0.5 to 2-megabase pair in survey results from TCGA (The Cancer Genome At- length. Yet, small genomic regions, 2–4 kb in length, are las) revealed that the expression levels of the major- known to control the imprinting of large genomic domains, ity of imprinted genes are downregulated in primary thus named Imprinting Control Regions (ICRs) (4). One tumors compared to normal cells. These changes of the main functions of ICRs is first to inherit germ cell- driven DNA methylation as a gametic signal, and later to are also accompanied by DNA methylation level maintain the subsequent allele-specific DNA methylation changes in several imprinted domains, such as the pattern within somatic cells (5).
    [Show full text]
  • Epigenetic Profiling of Mammalian Retrotransposons Arundhati Bakshi Louisiana State University and Agricultural and Mechanical College
    Louisiana State University LSU Digital Commons LSU Doctoral Dissertations Graduate School 2017 Epigenetic Profiling of Mammalian Retrotransposons Arundhati Bakshi Louisiana State University and Agricultural and Mechanical College Follow this and additional works at: https://digitalcommons.lsu.edu/gradschool_dissertations Part of the Life Sciences Commons Recommended Citation Bakshi, Arundhati, "Epigenetic Profiling of Mammalian Retrotransposons" (2017). LSU Doctoral Dissertations. 4357. https://digitalcommons.lsu.edu/gradschool_dissertations/4357 This Dissertation is brought to you for free and open access by the Graduate School at LSU Digital Commons. It has been accepted for inclusion in LSU Doctoral Dissertations by an authorized graduate school editor of LSU Digital Commons. For more information, please [email protected]. EPIGENETIC PROFILING OF MAMMALIAN RETROTRANSPOSONS A Dissertation Submitted to the Graduate Faculty of the Louisiana State University and Agricultural and Mechanical College in partial fulfillment of the requirements for the degree of Doctor of Philosophy in The Department of Biological Sciences by Arundhati Bakshi B.S., Louisiana State University, 2013 August 2017 ACKNOWLEDGEMENTS I joined Dr. Joomyeong Kim’s lab as an undergraduate student, a “newbie” to the world of science. He discovered in me the potential to be a good scientist, and then gave me the opportunity in his lab to realize that potential. For that, I will always remain grateful to Dr. Kim, my boss and mentor for the past six years. He gave me the opportunity to learn from his knowledge and experience, and his constructive criticisms frequently helped me fine-tune my ideas. He also trained me to think of science both in publication units as well as the “big- picture,” which is an invaluable skill for a scientist.
    [Show full text]
  • Allele and Dosage Specificity of the Peg3 Imprinted Domain
    Louisiana State University LSU Digital Commons Faculty Publications Department of Biological Sciences 5-1-2018 Allele and dosage specificity of the eg3P imprinted domain Corey L. Bretz Louisiana State University Wesley D. Frey Louisiana State University Ryoichi Teruyama Louisiana State University Joomyeong Kim Louisiana State University Follow this and additional works at: https://digitalcommons.lsu.edu/biosci_pubs Recommended Citation Bretz, C., Frey, W., Teruyama, R., & Kim, J. (2018). Allele and dosage specificity of the eg3P imprinted domain. PLoS ONE, 13 (5) https://doi.org/10.1371/journal.pone.0197069 This Article is brought to you for free and open access by the Department of Biological Sciences at LSU Digital Commons. It has been accepted for inclusion in Faculty Publications by an authorized administrator of LSU Digital Commons. For more information, please contact [email protected]. RESEARCH ARTICLE Allele and dosage specificity of the Peg3 imprinted domain Corey L. Bretz, Wesley D. Frey, Ryoichi Teruyama, Joomyeong Kim* Department of Biological Sciences, Louisiana State University, Baton Rouge, LA, United States of America * [email protected] Abstract a1111111111 The biological impetus for gene dosage and allele specificity of mammalian imprinted genes a1111111111 a1111111111 is not fully understood. To address this, we generated and analyzed four sets of mice from a1111111111 a single breeding scheme with varying allelic expression and gene dosage of the Peg3 a1111111111 domain. The mutants with abrogation of the two paternally expressed genes, Peg3 and Usp29, showed a significant decrease in growth rates for both males and females, while the mutants with biallelic expression of Peg3 and Usp29 resulted in an increased growth rate of female mice only.
    [Show full text]
  • Characterization of Boundary Element-Associated Factors BEAF-32A and BEAF-32B and Identification of Novel Interaction Partners in Drosophila Melanogaster S
    Louisiana State University LSU Digital Commons LSU Doctoral Dissertations Graduate School 2016 Characterization of Boundary Element-Associated Factors BEAF-32A and BEAF-32B and Identification of Novel Interaction Partners in Drosophila Melanogaster S. V. Satya Prakash Avva Louisiana State University and Agricultural and Mechanical College Follow this and additional works at: https://digitalcommons.lsu.edu/gradschool_dissertations Recommended Citation Avva, S. V. Satya Prakash, "Characterization of Boundary Element-Associated Factors BEAF-32A and BEAF-32B and Identification of Novel Interaction Partners in Drosophila Melanogaster" (2016). LSU Doctoral Dissertations. 617. https://digitalcommons.lsu.edu/gradschool_dissertations/617 This Dissertation is brought to you for free and open access by the Graduate School at LSU Digital Commons. It has been accepted for inclusion in LSU Doctoral Dissertations by an authorized graduate school editor of LSU Digital Commons. For more information, please [email protected]. CHARACTERIZATION OF BOUNDARY ELEMENT-ASSOCIATED FACTORS BEAF-32A AND BEAF-32B AND IDENTIFICATION OF NOVEL INTERACTION PARTNERS IN DROSOPHILA MELANOGASTER A Dissertation Submitted to the Graduate Faculty of the Louisiana State University and Agricultural and Mechanical College in partial fulfillment of the requirements for the degree of Doctor of Philosophy in The Department of Biological Sciences by S. V. Satya Prakash Avva B. Tech., ICFAI University, 2007 August 2016 I dedicate this to my father Late. Dr. Siva Rama Krishna Avva. You will always be in my thoughts. I remember the days when you came home from practice late in the night and still found the time to pick up a book. This vision of you, keeps me motivated, more than you could have ever imagined.
    [Show full text]
  • Departments and Offices Departments and Offices Melissa Brocato, Asst
    Departments and Offices Departments and Offices Melissa Brocato, Asst. Dir. 578-5293 Ashley Tate, Accountant - Travel 578-3698 A Roxanne Dill, Prog. Coord. BURSAR OPERATIONS (CCELL) . 578-4245 DIVISION . 578-3357 Acacia . 343-5845 Lisa Gullett, Adm. Coord. 578-2872 125 Thomas Boyd Hall FAX 578-3969 3733 W. Lakeshore Dr. Jeff Lee, Technology Intern. 578-4526 Laurence S. Butcher, Director & PO Box 25082 Diane Mohler, Study Strategies Bursar . 578-3681 Baton Rouge, LA 70894 Consult. 578-2522 Rebecca A. Kemp, Admin Soula O'Bannon, Coord. (Math Program Specialist . 578-3379 Academic Affairs (System) . 578-6118 Tutorial) . 578-1617 Daryl J. Dietrich, Associate 115 System Bldg. FAX 578-8835 Karthik Omanakuttan, Coord. Director . 578-5898 Carolyn H. Hargrave, Vice Pres. 578-6118 (Physics Tutorial) . 578-2618 Beth Nettles, Assistant Director 578-3249 Pam Bloom, Coord. 578-6118 Susan Saale, Supp. Instr. & Monica Esnault, Manager . 578-3335 Arthur Cooper, Tech. Mgt. Asst. to Tutorial Ctr. Coord. 578-4964 Dorothy S. Starns, Assistant the Vice Pres. for Acad. Aff. 615-8904 Jan Shoemaker, Dir. (CCELL) . 578-9264 Manager . 578-3377 Carla Fishman, Asst. to the Vice TUTORIAL CENTER, BIOLOGY & Katrina Barlow, Coordinator . 578-3380 Pres. for Acad. Aff. 578-6688 CHEMISTRY . 578-7744 Judy Williams, Accountant Nicole Honoree, Technology TUTORIAL CENTER, MATH . 578-2847 Supervisor . 578-3378 Transfer Specialist . 578-5471 TUTORIAL CENTER, PHYSICS 578-2618 Perkins Loans (part of Bursars) 578-3092 Ed Miller, Asst. Dir. of Fed. Acadian Hall . 334-2277 204 Thomas Boyd Hall FAX 578-3135 Aff./Asst. Dir. of Tech. Transfer 578-0252 Tiny (Virginia) Cazes, Admin Monica Santaella, Graduate Brent Cockrell, Res.
    [Show full text]
  • Joshua Meyer
    THOMAS JOSHUA MEYER Department of Biological Sciences 107 Life Sciences Building, Louisiana State University Ph. (251) 680-5554 y Email: [email protected] SUMMARY o Postdoctoral associate, Lab of Dr. Mark Batzer (College of Science, Louisiana State University) o Ph.D., Lab of Dr. Mark Batzer (College of Science, Louisiana State University) o Experience with a broad array of computational, molecular, and field biological techniques o Diverse teaching experience and student mentoring o Proven track record of problem-solving and team-building PROFESSIONAL EXPERIENCE Postdoctoral Associate (Louisiana State University): Jan. 2011 – Present • Advisor: Dr. Mark Batzer • Bioinformatics support for ongoing comparative genome projects • Repetitive element detection and phylogeny derivation from next-gen data • Installation and administration of Illumina GAIIx Linux server • Training and supervision of undergraduates Co-Instructor (Louisiana State University): Spring 2011 • Team taught Human Molecular Genetics (BIOL 4753) with Dr. Mark Batzer Graduate Teaching Assistant (Louisiana State University): 2005 – 2010 • Human Molecular Genetics (BIOL 4753) – Dr. Batzer, 3 semesters (2007, 2009, & 2010) • Microbiology Lab for Majors (BIOL 2051) – Dr. Brininstool, 6 semesters (2008 – 2010) • Introductory Biology Lab for Majors (BIOL 1209) – Dr. Wischusen, 4 semesters (2005 – 2007) • Evolution (BIOL 3040) – Dr. Pollock, 1 semester (Spring 2005) Graduate Mentor (Louisiana State University): Aug. 2008, 2009, & 2010 • Supervisor: Dr. Wischusen • BIOS: Biology
    [Show full text]
  • Download Sample
    Brief Table of Contents Table A The Genetic Code Second Position U C A G UNIT I: GENE TRANSMISSION AND FUNCTION UUU UCU UAU UGU U Phe (F) Tyr (Y) Cys (C) 1 The Molecular Basis of Heredity, Variation, and Evolution 1 UUC UCC UAC UGC C Ser (S) Transmission Genetics 26 U UCA 2 UUA UAA stop UGA stop A Leu (L) UCG 3 Cell Division and Chromosome Heredity 64 UUG UAG stop UGG Trp (W) G 4 Inheritance Patterns of Single Genes and Gene Interaction 104 CUU CCU CAU CGU U 5 Genetic Linkage and Mapping in Eukaryotes 144 His (H) CUC CCC CAC CGC C C Leu (L) Pro (P) Arg (R) Position (3 Third 6 Genetic Analysis and Mapping in Bacteria and Bacteriophages 186 CUA CCA CGA CAA A end) CUG CCG Gln (Q) CGG CAG G UNIT II: CENTRAL DOGMA AUU ACU AAU AGU U 7 DNA Structure and Replication 227 Asn (N) Ser (S) end) AUC Ile (I) ACC AAC AGC C 8 Molecular Biology of Transcription and RNA Processing 267 Position (5 First A Thr (T) AUA ACA AAA AGA A 9 The Molecular Biology of Translation 305 ACG Lys (K) Arg (R) AUG Met (M) AAG AGG G 10 The Integration of Genetic Approaches: Understanding Sickle Cell Disease 338 GUU GCU GAU GGU U Asp (D) UNIT III: GENOME STRUCTURE AND FUNCTION GUC GCC GAC GGC C G Val (V) Ala (A) Gly (G) GUA GCA GGA A 11 Chromosome Structure 365 GAA Glu (E) GUG GCG GGG G 12 Gene Mutation, DNA Repair, and Homologous Recombination 391 GAG 13 Chromosome Aberrations and Transposition 430 14 Regulation of Gene Expression in Bacteria and Bacteriophage 468 Table B Redundancy of the Genetic Code 15 Regulation of Gene Expression in Eukaryotes 504 Amino Acid Abbreviation
    [Show full text]
  • YY1's DNA-Binding Motifs in Mammalian Olfactory Receptor Genes Christopher D Faulk and Joomyeong Kim*
    BMC Genomics BioMed Central Research article Open Access YY1's DNA-Binding motifs in mammalian olfactory receptor genes Christopher D Faulk and Joomyeong Kim* Address: Department of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803, USA Email: Christopher D Faulk - [email protected]; Joomyeong Kim* - [email protected] * Corresponding author Published: 3 December 2009 Received: 21 April 2009 Accepted: 3 December 2009 BMC Genomics 2009, 10:576 doi:10.1186/1471-2164-10-576 This article is available from: http://www.biomedcentral.com/1471-2164/10/576 © 2009 Faulk and Kim; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: YY1 is an epigenetic regulator for a large number of mammalian genes. While performing genome-wide YY1 binding motif searches, we discovered that the olfactory receptor (OLFR) genes have an unusual cluster of YY1 binding sites within their coding regions. The statistical significance of this observation was further analyzed. Results: About 45% of the olfactory genes in the mouse have a range of 4-8 YY1 binding sites within their respective 1 kb coding regions. Statistical analyses indicate that this enrichment of YY1 motifs has likely been driven by unknown selection pressures at the DNA level, but not serendipitously by some peptides enriched within the OLFR genes. Similar patterns are also detected in the OLFR genes of all mammals analyzed, but not in the OLFR genes of the fish lineage, suggesting a mammal-specific phenomenon.
    [Show full text]
  • Allele and Dosage Specificity of the Peg3 Imprinted Domain
    RESEARCH ARTICLE Allele and dosage specificity of the Peg3 imprinted domain Corey L. Bretz, Wesley D. Frey, Ryoichi Teruyama, Joomyeong Kim* Department of Biological Sciences, Louisiana State University, Baton Rouge, LA, United States of America * [email protected] Abstract a1111111111 The biological impetus for gene dosage and allele specificity of mammalian imprinted genes a1111111111 a1111111111 is not fully understood. To address this, we generated and analyzed four sets of mice from a1111111111 a single breeding scheme with varying allelic expression and gene dosage of the Peg3 a1111111111 domain. The mutants with abrogation of the two paternally expressed genes, Peg3 and Usp29, showed a significant decrease in growth rates for both males and females, while the mutants with biallelic expression of Peg3 and Usp29 resulted in an increased growth rate of female mice only. The mutant cohort with biallelic expression of Peg3 and Usp29 tended to OPEN ACCESS have greater numbers of pups compared to the other genotypes. The mutants with switched Citation: Bretz CL, Frey WD, Teruyama R, Kim J active alleles displayed overall similar phenotypes to the wild type, but did show some differ- (2018) Allele and dosage specificity of the Peg3 ences in gene expression, suggesting potential non-redundant roles contributed by the imprinted domain. PLoS ONE 13(5): e0197069. maternal and paternal alleles. Overall, this study demonstrates a novel in vivo approach to https://doi.org/10.1371/journal.pone.0197069 investigate the allele and dosage specificity of mammalian imprinted domains. Editor: Keith William Brown, University of Bristol, UNITED KINGDOM Received: March 16, 2018 Accepted: April 25, 2018 Introduction Published: May 7, 2018 In placental mammals, the majority of autosomal genes have two functional copies, which are Copyright: © 2018 Bretz et al.
    [Show full text]
  • Characterization of the Promoter and Insulator Activities of the Scs' Insulator Yu Ge Louisiana State University and Agricultural and Mechanical College, [email protected]
    Louisiana State University LSU Digital Commons LSU Master's Theses Graduate School 2012 Characterization of the Promoter and Insulator Activities of the Scs' Insulator Yu Ge Louisiana State University and Agricultural and Mechanical College, [email protected] Follow this and additional works at: https://digitalcommons.lsu.edu/gradschool_theses Recommended Citation Ge, Yu, "Characterization of the Promoter and Insulator Activities of the Scs' Insulator" (2012). LSU Master's Theses. 3574. https://digitalcommons.lsu.edu/gradschool_theses/3574 This Thesis is brought to you for free and open access by the Graduate School at LSU Digital Commons. It has been accepted for inclusion in LSU Master's Theses by an authorized graduate school editor of LSU Digital Commons. For more information, please contact [email protected]. CHARACTERIZATION OF THE PROMOTER AND INSULATOR ACTIVITIES OF THE SCS’ INSULATOR A Thesis Submitted to the Graduate Faculty of the Louisiana State University and Agricultural and Mechanical College in partial fulfillment of the requirements of the degree of Master of Science in The Department of Biological Science by Yu Ge B.S., Sichuan Agricultural University, 2009 August 2012 ACKNOWLEDGMENTS I would like to thank Dr. Craig Hart, my major professor, for his patience and guidance and also Dr. Patrick DiMario, Dr. David Donze, and Dr. Joomyeong Kim, my dissertation committee members, for their scientific advice and time. I would also like to thank members in Dr. Craig Hart lab and Dr. Patrick DiMario lab: Avva Satya, Shraddha Shrestha, Brandon Finnorn, Trace Favre, Allison James and Yubo Wang for their great help in my research and life. I would also like to acknowledge the Department of Biological Science and Graduate School for their financial support for my graduate study.
    [Show full text]