Anti-ECSIT Monoclonal Antibody (DCABH-15245) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-ECSIT monoclonal antibody (DCABH-15245) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity). Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase.

Immunogen A synthetic peptide of human ECSIT is used for rabbit immunization.

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Protein A

Conjugate Unconjugated

Applications Western Blot (Transfected lysate); ELISA

Size 1 ea

Buffer In 1x PBS, pH 7.4

Preservative None

Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

GENE INFORMATION

Gene Name ECSIT ECSIT homolog (Drosophila) [ Homo sapiens ]

Official Symbol ECSIT

Synonyms ECSIT; ECSIT homolog (Drosophila); evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; signaling intermediate in Toll pathway evolutionarily conserved ortholog (mouse); SITPEC; likely ortholog of mouse signaling intermediate in Toll pathway evolutionarily conserved;

Entrez Gene ID 51295

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

UniProt ID Q9BQ95

Chromosome Location 19p13.2

Pathway Activated TLR4 signalling, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem

Function oxidoreductase activity, acting on NADH or NADPH; protein binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]