DOCSLIB.ORG

Valparaiso City Utilities M.A.P. Mercury Awareness Program

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Valparaiso City Utilities M.A.P. Mercury Awareness Program Where Is Mercury In My Home? How Do I Dispose Of Mercury Valparaiso City Utilities Containing Items Safely? Many household items may contain mercury. Use the M.A.P. Mercury Search checklist to conduct your home in- You should first contact Porter County Recycling & Mercury Awareness Program ventory. These items pose no threat to you or your Waste Reduction at (219) 465-3694 or visit their web- family when used properly. They can be hazardous if site www.itmeanstheworld.org. Go to “Services” and misused or improperly disposed. Look for these mer- then to “ Hazardous Waste.” cury containing items in your home: Things to remember when disposing of objects contain- Fever thermometers and antiseptic products that contain thimerosal or merbromin in the bath- ing mercury: room, kitchen or bedroom. Fluorescent lights in the bathroom, basement, Never break open items that contain mercury. garage or shed. Mercury thermostats. Never pour mercury down the drain. Clothes irons in the broom closet, kitchen, laun- Never burn mercury. dry room or bedroom. How Can I Prevent Mercury Pollution? Never put mercury in the trash. Minimizing mercury releases from all sources is im- portant. Local and state governments are working in partnership with businesses to develop collection sys- tems for mercury. Here’s what you can do: Know which items contain mercury. Use the Mercury Checklist that accompanies this bro- chure to do an inventory of mercury containing items in your home. Avoid buying products that contain mercury, except fluorescent light bulbs. Fluorescent lights www.ci.valparaiso.in.us use less electricity than incandescent bulbs. Label or use a “Contains Mercury-Recycle” sticker to identity mercury containing items. Industrial Pretreatment Coordinator Conserve energy to reduce coal burning for elec- Valparaiso City Utilities tricity generation. Water Reclamation Department Properly recycle mercury containing items, such 1251 Joliet Road as batteries or thermostats. Valparaiso, IN 46385 What Is Mercury? Mercury Checklist: A Little Bit of Mercury is a Lot Thermometers: silver colored liquid inside. Mercury is toxic in small quantities. It only takes 3 Mercury, also known as quicksilver, is one of 92 natu- grams (approximately 1/25 of a ral occurring elements in our world. It is a metal that Thermostats: nonelectric. teaspoon) of mercury to contam- conducts electricity and is liquid at room temperature. inate a 60 acre lake. Because of these properties, mercury has been used in Fluorescent and other Mercury Vapor Light- ing: HID (high intensity discharge), metal many household, medical, industrial and scientific halide, high pressure sodium and neon bulbs. A typical mercury fever products. thermometer contains about 0.6 grams of mercury per Automotive Headlamps: blue tint when lit. USEPA. Although mercury does perform many useful functions in our workplaces and homes, it is toxic and can im- Pilot Light Sensors: in some gas appliances: A mercury switch contains about 3.5 grams of pair the way we see, hear and function. stoves, ovens, clothes dryers, water heaters, fur- naces and space heaters. mercury. Mercury evaporates slowly. If Gauges: barometers, manometers, blood A mercury thermostat contains about 3 grams spilled or improperly stored, the pressure and vacuum gauges with silver colored of mercury. evaporation of mercury will cause liquid. continuous contamination of the air Switches and Relays: in some chest freezers, 100 4 foot fluores- you breathe. pre-1972 washing machines, sump pump and cent bulbs contain bilge pumps, electric space heaters, silent light about 4 grams of switches, vehicles and farm equipment. mercury. Clothes Irons: automatic or tilt shut offs. Mercury poisoning via breathing contaminated air will attack the central nervous system in all humans. Chil- Elemental Mercury: silver colored liquid dren, especially those under the age of 6, are most sus- metal sometimes found in children’s chemistry ceptible to mercury poisoning. sets. For More Information Or Assistance Call: Less than a third of the mercury in the environment is Vintage Toys: paint on toys and mercury maze games. naturally occurring. The majority of mercury in the Porter County Recycling and Waste Reduction environment is released through human activities. It LA Gear Athletic Shoes: made before 1997 can enter the atmosphere, lakes and streams from coal with flashing lights in soles. District (219) 465-3694. www.itmeanstheworld.org burning for power generation, from industrial sources and by improper disposal of mercury containing scien- Batteries: mercuric oxide and some alkaline tific and household products. batteries. Indiana Department of Environmental Management Paint: latex manufactured before 1990, and (317) 232-8603. www.in.gov/idem/4245.htm When mercury seeps into lakes and some oil base paints; check label. waterways, it undergoes a natural Industrial Pretreatment Coordinator chemical process and is converted to Thimerosal or Merbromin: in some antibac- –methyl mercury. It can contaminate terial products. Valparaiso City Utilities the food chain by building up in the tissue of fish and animals. The State of Indiana will Look for Other Items: this list is not com- Water Reclamation Department issue fish consumption advisories due to high mercury plete. (219) 462-6174 x1366 concentrations found in fish. The advisories are availa- ble from your local health department. www.ci.valparaiso.in.us .
Load more

Recommended publications
  • Selling Mercury Cosmetics and Pharmaceuticals (W-Hw4-22)
    www.pca.state.mn.us Selling mercury cosmetics and pharmaceuticals Mercury-containing skin lightening creams, lotions, soaps, ointments, lozenges, pharmaceuticals and antiseptics Mercury is a toxic element that was historically used in some cosmetic, pharmaceutical, and antiseptic products due to its unique properties and is now being phased out of most uses. The offer, sale, or distribution of mercury-containing products is regulated in Minnesota by the Minnesota Pollution Control Agency (MPCA). Anyone offering a mercury-containing product for sale or donation in Minnesota is subject to these requirements, whether a private citizen, collector, non-profit organization, or business. Offers and sales through any method are regulated, whether in a store or shop, classified advertisement, flea market, or online. If a mercury-containing product is located in Minnesota, it is regulated, regardless of where a purchaser is located. Note: This fact sheet discusses the requirements and restrictions of the MPCA. Cosmetics and pharmaceuticals may also be regulated for sale whether they contain mercury or not by other state or federal agencies, including the Minnesota Board of Pharmacy and the U.S. Food & Drug Administration. See More information on page 2. What are the risks of using mercury-containing products? Use of mercury-containing products can damage the brain, kidneys, and liver. Children and pregnant women are at increased risk. For more information about the risks of mercury exposure, visit the Minnesota Department of Health. See More information on the page 2. If you believe you have been exposed to a mercury-containing product, contact your health care provider or the Minnesota Poison Control Center at 1-800-222-1222.
    [Show full text]
  • A Screening-Based Approach to Circumvent Tumor Microenvironment
    JBXXXX10.1177/1087057113501081Journal of Biomolecular ScreeningSingh et al. 501081research-article2013 Original Research Journal of Biomolecular Screening 2014, Vol 19(1) 158 –167 A Screening-Based Approach to © 2013 Society for Laboratory Automation and Screening DOI: 10.1177/1087057113501081 Circumvent Tumor Microenvironment- jbx.sagepub.com Driven Intrinsic Resistance to BCR-ABL+ Inhibitors in Ph+ Acute Lymphoblastic Leukemia Harpreet Singh1,2, Anang A. Shelat3, Amandeep Singh4, Nidal Boulos1, Richard T. Williams1,2*, and R. Kiplin Guy2,3 Abstract Signaling by the BCR-ABL fusion kinase drives Philadelphia chromosome–positive acute lymphoblastic leukemia (Ph+ ALL) and chronic myelogenous leukemia (CML). Despite their clinical activity in many patients with CML, the BCR-ABL kinase inhibitors (BCR-ABL-KIs) imatinib, dasatinib, and nilotinib provide only transient leukemia reduction in patients with Ph+ ALL. While host-derived growth factors in the leukemia microenvironment have been invoked to explain this drug resistance, their relative contribution remains uncertain. Using genetically defined murine Ph+ ALL cells, we identified interleukin 7 (IL-7) as the dominant host factor that attenuates response to BCR-ABL-KIs. To identify potential combination drugs that could overcome this IL-7–dependent BCR-ABL-KI–resistant phenotype, we screened a small-molecule library including Food and Drug Administration–approved drugs. Among the validated hits, the well-tolerated antimalarial drug dihydroartemisinin (DHA) displayed potent activity in vitro and modest in vivo monotherapy activity against engineered murine BCR-ABL-KI–resistant Ph+ ALL. Strikingly, cotreatment with DHA and dasatinib in vivo strongly reduced primary leukemia burden and improved long-term survival in a murine model that faithfully captures the BCR-ABL-KI–resistant phenotype of human Ph+ ALL.
    [Show full text]
  • United States Patent (19) 11 Patent Number: 6,039,940 Perrault Et Al
    US0060399.40A United States Patent (19) 11 Patent Number: 6,039,940 Perrault et al. (45) Date of Patent: Mar. 21, 2000 54) INHERENTLY ANTIMICROBIAL 5,563,056 10/1996 Swan et al.. QUATERNARY AMINE HYDROGEL WOUND 5,599.321 2/1997 Conway et al.. DRESSINGS 5,624,704 4/1997 Darouiche et al.. 5,670.557 9/1997 Dietz et al.. 75 Inventors: James J. Perrault, Vista, Calif.; 5,674.561 10/1997 Dietz et al.. Cameron G. Rouns, Pocatello, Id. 5,800,685 9/1998 Perrault. FOREIGN PATENT DOCUMENTS 73 Assignee: Ballard Medical Products, Draper, Utah 92/06694 4/1992 WIPO. WO 97/14448 4/1997 WIPO. 21 Appl. No.: 09/144,727 OTHER PUBLICATIONS 22 Filed: Sep. 1, 1998 I. I. Raad, “Vascular Catheters Impregnated with Antimi crobial Agents: Present Knowledge and Future Direction,” Related U.S. Application Data Infection Control and Hospital Epidemiology, 18(4): 63 Continuation-in-part of application No. 08/738,651, Oct. 28, 227–229 (1997). 1996, Pat. No. 5,800,685. R. O. Darouiche, H. Safar, and I. I. Raad, “In Vitro Efficacy of Antimicrobial-Coated Bladder Catheters in Inhibiting 51) Int. Cl." .......................... A61K31/785; A61F 13/00 Bacterial Migration along Catheter Surface,” J. Infect. Dis., 52 U.S. Cl. ..................................... 424/78.06; 424/78.08; 176: 1109-12 (1997). 424/78.35; 424/78.37; 424/443; 424/445 W. Kohen and B. Jansen, “Polymer Materials for the Pre 58 Field of Search ..................................... 424/443, 445, vention of Catheter-related Infections.” Zbl Bakt., 283: 424/78.06, 78.07, 78.08, 78.35, 78.37 175-186 (1995).
    [Show full text]
  • Identification of Drug Candidates That Enhance Pyrazinamide Activity from a Clinical Drug Library
    bioRxiv preprint doi: https://doi.org/10.1101/113704; this version posted March 4, 2017. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. Identification of drug candidates that enhance pyrazinamide activity from a clinical drug library Hongxia Niub, a, Chao Mac, Peng Cuid, Wanliang Shia, Shuo Zhanga, Jie Fenga, David Sullivana, Bingdong Zhu b, Wenhong Zhangd, Ying Zhanga,d* a Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA b Lanzhou Center for Tuberculosis Research and Institute of Pathogenic Biology, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China c College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China d Key Laboratory of Medical Molecular Virology, Department of Infectious Diseases, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China *Correspondence: Ying Zhang, E-Mail: yzhang@jhsph.edu Tuberculosis (TB) remains a leading cause of morbidity and mortality globally despite the availability of the TB therapy. 1 The current TB therapy is lengthy and suboptimal, requiring a treatment time of at least 6 months for drug susceptible TB and 9-12 months (shorter Bangladesh regimen) or 18-24 months (regular regimen) for multi-drug-resistant tuberculosis (MDR-TB). 1 The lengthy therapy makes patient compliance difficult, which frequently leads to emergence of drug-resistant strains. The requirement for the prolonged treatment is thought to be due to dormant persister bacteria which are not effectively killed by the current TB drugs, except rifampin and pyrazinamide (PZA) which have higher activity against persisters.
    [Show full text]
  • Risks to Health and the Environment Related to the Use of Mercury Products
    Ref. Ares(2015)4242228 - 12/10/2015 Risks to Health and the Environment Related to the Use of Mercury Products Final Report prepared for The European Commission, DG Enterprise by Risk & Policy Analysts Limited, Farthing Green House, 1 Beccles Road, Loddon, Norfolk, NR14 6LT Tel: 01508 528465 Fax: 01508 520758 Email: post@rpaltd.demon.co.uk Web: www.rpaltd.co.uk RPA REPORT - ASSURED QUALITY Project: Ref/Title J372/Mercury Approach: In accordance with the Contract, Scoping Meeting with the Commission and associated discussions Report Status: Final Report Authors: Dr P Floyd & P Zarogiannis, RPA Dr M Crane, Crane Consultants Prof S Tarkowski, Nofer Institute of Occupational Medicine (Poland) Prof V Bencko, Charles University of Prague Approved for Issue by: Ms M Postle, Director Date: 9 August, 2002 If printed by RPA, this report will be on chlorine free, 100% recycled paper. Risk & Policy Analysts EXECUTIVE SUMMARY Overview Mercury and its compounds are hazardous materials which may pose risks to people and to the environment. This report presents an assessment of the risks associated with the use of mercury in a range of products. The key requirements of the study were: • to identify usage of mercury in dental amalgam, batteries, measuring instruments (such as thermometers and manometers), lighting, other electrical components and other lesser uses; • to review data used to evaluate the toxicity of mercury and mercury compounds to humans and to the environment; • to derive predicted environmental concentrations (PECs) associated with use of the products under consideration and compare with those associated with other sources of mercury; and • to characterise the associated risks.
    [Show full text]
  • Survey of Mercury and Mercury Compounds
    Survey of mercury and mercury compounds Part of the LOUS-review Environmental Project No. 1544, 2014 Title: Authors and contributors: Survey of mercury and mercury compounds Jakob Maag Jesper Kjølholt Sonja Hagen Mikkelsen Christian Nyander Jeppesen Anna Juliana Clausen and Mie Ostenfeldt COWI A/S, Denmark Published by: The Danish Environmental Protection Agency Strandgade 29 1401 Copenhagen K Denmark www.mst.dk/english Year: ISBN no. 2014 978-87-93026-98-8 Disclaimer: When the occasion arises, the Danish Environmental Protection Agency will publish reports and papers concerning research and development projects within the environmental sector, financed by study grants provided by the Danish Environmental Protection Agency. It should be noted that such publications do not necessarily reflect the position or opinion of the Danish Environmental Protection Agency. However, publication does indicate that, in the opinion of the Danish Environmental Protection Agency, the content represents an important contribution to the debate surrounding Danish environmental policy. While the information provided in this report is believed to be accurate, the Danish Environmental Protection Agency disclaims any responsibility for possible inaccuracies or omissions and consequences that may flow from them. Neither the Danish Environmental Protection Agency nor COWI or any individual involved in the preparation of this publication shall be liable for any injury, loss, damage or prejudice of any kind that may be caused by persons who have acted based on their understanding of the information contained in this publication. Sources must be acknowledged. 2 Survey of mercury and mercury compounds Contents Preface ...................................................................................................................... 5 Summary and conclusions ......................................................................................... 7 Sammenfatning og konklusion ................................................................................ 14 1.
    [Show full text]
  • United States Patent Office Patented Aug
    3,751,562 United States Patent Office Patented Aug. 7, 1973 2 3,751,562 chlorophene, with a gelled oil. The base for these com MEDICATED GELLIED OLS Joseph Nichols, Princeton, N.J., assignor to Princeton positions is preferably a mineral oil gelled by at least one Biomedix incorporated, Princeton, N.Y. polyoxyethylated fatty acid alcohol ether. No Drawing. Continuation-in-part of abandoned applica Accordingly, it is a primary object of the present in tion Ser. No. 28,124, Apr. 13, 1970. This application vention to provide a topical medicament which is free Sept. 22, 1972, Ser. No. 291,239 of the aforementioned and other such disadvantages. Ent. C. A61k 9/06, 27/00 It is another primary object of the present invention U.S. C. 424-45 Clains to provide a carrier for a topical medicament which is clear, Water-soluble, aesthetically pleasing, and non-irri O tating. ABSTRACT OF THE DISCLOSEURE It is another object of the present invention to provide Medicated gelled oils suitable for topical application are a topical antiseptic composition which is relatively in disclosed. The gelled oils which form an ointment base are expensive to manufacture and easy to apply. mineral oils gelled with at least one polyoxyethylated It is still another object of the present invention to pro fatty acid alcohol ether. The base can be compounded 5 vide an antiseptic composition containing iodine, which With any conventional topical medicament for use as a composition is non-irritating, easy to apply, and has a germicide, fungicide, or anesthetic. long-lasting effect. Yet another object of the present invention is to pro This application is a continuation-in-part of co-pending vide an antiseptic composition containing thimerosal, application Ser.
    [Show full text]
  • Scheduling: Delegates Reasons for Interim Decisions
    INTERIM DECISIONS & REASONS FOR DECISIONS BY THE DELEGATE OF THE SECRETARY TO THE DEPARTMENT OF HEALTH AND AGEING INVITATION FOR COMMENT Notice under subsection 42ZCZP of the Therapeutic Goods Regulations 1990 (the Regulations) The Delegate of the Secretary to the Department of Health and Ageing hereby gives notice of the delegate’s interim decisions under subsection 42ZCZP of the Therapeutic Goods Regulations 1990. This notice provides the interim decisions of the delegate, the reasons for those decisions and invites comment from the applicant and parties who made a valid submission in response to the original invitation for comment (published on 29 September 2010 at http://www.tga.gov.au/newsroom/consult-scheduling-acmcs.htm). Edited versions of these submissions are available at http://www.tga.gov.au/industry/scheduling- decisions.htm. If no submissions were received to the original invitation, then the delegate may choose to confirm the interim decision as the final decision. Submissions must be relevant to the proposed amendment, must address a matter mentioned in section 52E of the Therapeutic Goods Act 1989 and be received by the closing date (2 March 2011). Submissions from parties other than those who made a valid submission in response to the original invitation or the applicant, or those received after the closing date, need not be considered by the delegate. Please note that all valid submissions received on or before the closing date will be published following removal of confidential information. It is up to the person making the submission to highlight any information which they wish to be considered as confidential.
    [Show full text]
  • FOI 161-112 Document 1
    \/ Fw: IDC - Mercury L fy [SEC=:UNCLASSIFIED] 09/12/2010 04:23 PM - This is the fi rst of two emails I will send - this is our response to the questions posed by the UNEP f""I secretariat after the first in June. INC ...., C Kind regards, QJ E :::l ..*******��***************�************ u o International Coordination Team c Office of Parliamentary and Strategic Support Therapeutic Goods Administration E-mail: tga.internatlonal@tga.gov.au ----- Forwarded n 09/12/20"10 04:21 PM ---_. To 'ilenvironmentgov,au> · cc !ilenvironment.gov,au>, environment.gov,au>_ "" 11/11/2010 .. .. 02:14 PM Subject Re: IDC - Mercury LBI- Friday 23 July [SEC=UNCLASSIFIED} Dear_ Please find attached TGA's contribution to the mercury data gaps identified by the UNEP Secretariat. Should you have any queries or concerns relating to tllis information, we would be very happy to discuss these at our meeting tomorrow (Friday 12 November at 3pm), TGA participants at tomorrow's meeting will be: Devices Authorisation Office of Scientific Evaluation Services _ill also be there, representing the International Coordination team. Please note that we are correctly identified as stakeholders for the Regulation sector (arrangements for labelling products containing mercury), but mistakenly included as a stakeholder for the sector for uni ntentional emission (biomedical waste i Ilcineration), Kind regards, International Coordination Tearn Office of Parliamentary aild Strategic Support Therapeutic Goods Administration E�mail: tga.international@tga.go.J.au o - Mercury in ther�peutic products - Response for UNEP INC Oct 201 O.DOCX Dear Colleagues FOl owlng u� ercury �BI meeting on FridLY'23 July, we would li ke to t from t� �C � M request for )tell assl�� ce In addressing the mercury data gaps that the UNEP Secretariat has identified.
    [Show full text]
  • Bulk Drug Substances Nominated for Use in Compounding Under Section 503B of the Federal Food, Drug, and Cosmetic Act
    Updated June 07, 2021 Bulk Drug Substances Nominated for Use in Compounding Under Section 503B of the Federal Food, Drug, and Cosmetic Act Three categories of bulk drug substances: • Category 1: Bulk Drug Substances Under Evaluation • Category 2: Bulk Drug Substances that Raise Significant Safety Risks • Category 3: Bulk Drug Substances Nominated Without Adequate Support Updates to Categories of Substances Nominated for the 503B Bulk Drug Substances List1 • Add the following entry to category 2 due to serious safety concerns of mutagenicity, cytotoxicity, and possible carcinogenicity when quinacrine hydrochloride is used for intrauterine administration for non- surgical female sterilization: 2,3 o Quinacrine Hydrochloride for intrauterine administration • Revision to category 1 for clarity: o Modify the entry for “Quinacrine Hydrochloride” to “Quinacrine Hydrochloride (except for intrauterine administration).” • Revision to category 1 to correct a substance name error: o Correct the error in the substance name “DHEA (dehydroepiandosterone)” to “DHEA (dehydroepiandrosterone).” 1 For the purposes of the substance names in the categories, hydrated forms of the substance are included in the scope of the substance name. 2 Quinacrine HCl was previously reviewed in 2016 as part of FDA’s consideration of this bulk drug substance for inclusion on the 503A Bulks List. As part of this review, the Division of Bone, Reproductive and Urologic Products (DBRUP), now the Division of Urology, Obstetrics and Gynecology (DUOG), evaluated the nomination of quinacrine for intrauterine administration for non-surgical female sterilization and recommended that quinacrine should not be included on the 503A Bulks List for this use. This recommendation was based on the lack of information on efficacy comparable to other available methods of female sterilization and serious safety concerns of mutagenicity, cytotoxicity and possible carcinogenicity in use of quinacrine for this indication and route of administration.
    [Show full text]
  • Mercury Survey College of Pharmacy
    Appendix A - Survey Tools ACADEMIC LABORATORY MERCURY MINIMALIZATION | SECURED DOCUMENT Academic Affairs Laboratory Safety Mercury Survey College of Pharmacy Number: AALSSD 2-30-3500 CP-F01 Author: Anne Hawkins Effective Date: Revision Date: Accepted/ Issued: Name of individual filling out survey: Title: Phone: Please indicate if the following mercury sources are located or used in your Department I. Equipment: Barometers Batteries Centrifuges Fever Thermometers Hood Manometer Sphygmomanometers Thermostats Other II. Chemicals/Staining Solutions & Preservatives: Mercury iodide Mercury (I) Bromide Mercury (I) Carbonate Mercury (I) Chloride Mercury (I) Chromate Mercury (I) Dichromate Mercury (I) Nitrate Mercury (I) Nitrate Mercury (I) Oxide Mercury (I) Sulfate Mercury (I) Sulfide Mercury (II) Acetate Mercury (II) Ammonium Thoocyanate Mercury (II) Bromate Mercury (II) Bromide Mercury (II) Carbonate Mercury (II) Chlorate Mercury (II) Chloride Mercury (II) Chromate Mercury (II) Dichromate Mercury (II) Hydrogen Carbonate Mercury (II) Hydroxide Mercury (II) Iodate Mercury (II) Nitrate Mercury (II) Nitrate Monohydrate Mercury (II) Nitrite Mercury (II) Oxide Mercury (II) Nitride Mercury (II) Phosphate Mercury (II) Sulfate Mercury (II) Sulfide Mercury (II) Thiosulfate Commercial Chemical Products Acetate Acetic acid Alum Ammonium reagent/Stone analysis kit Antibody test kits Antigens Buffers Chloride Diluents Ethanol Fixatives Immunoelectrophoresis reagents Immunofixationphoresis reagents: Immu-sal Potassium hydroxide Shigella bacteria Sodium hypochlorite Sulfuric acid Thimerosal T Tracer kits Urine analysis reagents Other III. Drug & Biologic Products- Thimerosal: Akorn Inc. AK Spore Ophthalmic Solution AK Spore HC Ophthalmic Combo Drops Fluoracaine Ophthalmic Solution AK Spore HC Otic Suspension Alcon Laboratories Profenal 1% Ophthalmic Solution Adsorbonac 2% Ophthalmic Solution Adsorbonac 5% Ophthalmic Solution Allergan America Ocufen Ophthalmic Solution Poly Pred Ophthalmic Suspension Allergan Inc.
    [Show full text]
  • Bulk Drug Substances Nominated for Use in Compounding Under Section 503B of the Federal Food, Drug, and Cosmetic Act
    Updated July 30, 2020 Bulk Drug Substances Nominated for Use in Compounding Under Section 503B of the Federal Food, Drug, and Cosmetic Act Three categories of bulk drug substances: • Category 1: Bulk Drug Substances Under Evaluation • Category 2: Bulk Drug Substances that Raise Significant Safety Risks • Category 3: Bulk Drug Substances Nominated Without Adequate Support Notice of Updates to Categories of Substances Nominated for the 503B Bulk Drug Substances List • Additions to category 1: Betahistine Hydrochloride L-Proline Citrulline Papaverine Hydrochloride* Copper Gluconate Phosphatidylcholine Diiodohydroxyquinoline Podophyllum Resin Glucosamine Sulfate Potassium Chloride Sodium Molybdate Glucosamine Sulfate Sodium Chloride Sodium Nitroprusside Hydrochloric Acid* Sodium Selenite/Sodium Selenite Pentahydrate* Ibutamoren Mesylate Trichloroacetic Acid* L-Citrulline* Ubidecarenone (Coenzyme Q10)* L-Lysine * Bulk drug substance is currently in Category 3 and is being moved to Category 1. • Minor revision to entry in Category 1 to correct a misspelling: o Correct the misspelling of “cimatidine” to “cimetidine” 1 Updated July 30, 2020 503B Category 1: Bulk Drug Substances Under Evaluation • 5-Methyltetrahydrofolate Calcium • Chromic Chloride • 17-alpha-Hydroxyprogesterone • Chromium chloride/ Chromium Chloride • Acetylcysteine Hexahydrate • Acyclovir • Ciclopirox Oleate • Adapalene • Cimetidine • Adenosine • Ciprofloxacin HCl • Allantoin • Citric Acid Anhydrous • Alpha Lipoic Acid • Citrulline/L-Citrulline • Alprostadil • Clindamycin Phosphate
    [Show full text]