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Safety Data Sheet SAFETY DATA SHEET Creation Date 10-Jun-2011 Revision Date 17-Dec-2020 Revision Number 6 SECTION 1: IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1. Product identifier Product Description: Lithium aluminium hydride, 2.4M solution in THF Cat No. : 377320000; 377321000; 377328000 Synonyms LAH; Lithium tetrahydridoaluminate; Lithiumalanate. Unique Formula Identifier (UFI) XQ1Q-U2R1-AX0C-9P3W 1.2. Relevant identified uses of the substance or mixture and uses advised against Recommended Use Laboratory chemicals. Uses advised against No Information available 1.3. Details of the supplier of the safety data sheet Company UK entity/business name Fisher Scientific UK Bishop Meadow Road, Loughborough, Leicestershire LE11 5RG, United Kingdom EU entity/business name Acros Organics BVBA Janssen Pharmaceuticalaan 3a 2440 Geel, Belgium E-mail address [email protected] 1.4. Emergency telephone number For information US call: 001-800-ACROS-01 / Europe call: +32 14 57 52 11 Emergency Number US:001-201-796-7100 / Europe: +32 14 57 52 99 CHEMTREC Tel. No.US:001-800-424-9300 / Europe:001-703-527-3887 Poison Centre - Emergency Ireland : National Poisons Information Centre (NPIC) - information services 01 809 2166 (8am-10pm, 7 days a week) Malta : +356 2395 2000 Cyprus : +357 2240 5611 SECTION 2: HAZARDS IDENTIFICATION 2.1. Classification of the substance or mixture CLP Classification - Regulation (EC) No 1272/2008 Physical hazards Flammable liquids Category 2 (H225) Substances/mixtures which, in contact with water, emit flammable gases Category 1 (H260) ______________________________________________________________________________________________ ACR37732 Page 1 / 12 SAFETY DATA SHEET Lithium aluminium hydride, 2.4M solution in THF Revision Date 17-Dec-2020 ______________________________________________________________________________________________ Health hazards Acute oral toxicity Category 4 (H302) Skin Corrosion/Irritation Category 1 A (H314) Serious Eye Damage/Eye Irritation Category 1 (H318) Carcinogenicity Category 2 (H351) Specific target organ toxicity - (single exposure) Category 3 (H335) (H336) Environmental hazards Based on available data, the classification criteria are not met Full text of Hazard Statements: see section 16 2.2. Label elements Signal Word Danger Hazard Statements H225 - Highly flammable liquid and vapor H260 - In contact with water releases flammable gases which may ignite spontaneously H302 - Harmful if swallowed H314 - Causes severe skin burns and eye damage H335 - May cause respiratory irritation H336 - May cause drowsiness or dizziness H351 - Suspected of causing cancer EUH019 - May form explosive peroxides Precautionary Statements P280 - Wear protective gloves/protective clothing/eye protection/face protection P301 + P330 + P331 - IF SWALLOWED: Rinse mouth. Do NOT induce vomiting P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P310 - Immediately call a POISON CENTER or doctor/physician P231 + P232 - Handle and store contents under inert gas. Protect from moisture. P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking 2.3. Other hazards Reacts violently with water Toxic to terrestrial vertebrates SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS ______________________________________________________________________________________________ ACR37732 Page 2 / 12 SAFETY DATA SHEET Lithium aluminium hydride, 2.4M solution in THF Revision Date 17-Dec-2020 ______________________________________________________________________________________________ 3.2. Mixtures Component CAS-No EC-No. Weight % CLP Classification - Regulation (EC) No 1272/2008 Tetrahydrofuran 109-99-9 EEC No. 203-726-8 90 Flam. Liq. 2 (H225) Acute Tox. 4 (H302) Eye Irrit. 2 (H319) STOT SE 3 (H335) STOT SE 3 (H336) Carc. 2 (H351) (EUH019) Lithium aluminum hydride 16853-85-3 EEC No. 240-877-9 10 Skin Corr. 1A (H314) Eye Dam. 1 (H318) Water-react. 1 (H260) Component Specific concentration limits M-Factor Component notes (SCL's) Tetrahydrofuran STOT SE 3 :: C>=25% - - Eye Irrit. 2 :: C>=25% Acute Tox. 4 :: C>82.5% Components Reach Registration Number Tetrahydrofuran 01-2119444314-46 Lithium aluminum hydride 01-2119919039-36 Full text of Hazard Statements: see section 16 SECTION 4: FIRST AID MEASURES 4.1. Description of first aid measures General Advice Show this safety data sheet to the doctor in attendance. Immediate medical attention is required. Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required. Skin Contact Wash off immediately with plenty of water for at least 15 minutes. Remove and wash contaminated clothing and gloves, including the inside, before re-use. Call a physician immediately. Ingestion Do NOT induce vomiting. Clean mouth with water. Never give anything by mouth to an unconscious person. Call a physician immediately. Inhalation If not breathing, give artificial respiration. Remove from exposure, lie down. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Call a physician immediately. Self-Protection of the First Aider Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and prevent spread of contamination. 4.2. Most important symptoms and effects, both acute and delayed Causes burns by all exposure routes. Symptoms of overexposure may be headache, dizziness, tiredness, nausea and vomiting: Product is a corrosive material. Use of gastric lavage or emesis is contraindicated. Possible perforation of stomach or esophagus should be investigated: Ingestion causes severe swelling, severe damage to the delicate tissue and danger of perforation: Inhalation of high vapor concentrations may cause symptoms like headache, dizziness, tiredness, nausea and vomiting: Causes central nervous system ______________________________________________________________________________________________ ACR37732 Page 3 / 12 SAFETY DATA SHEET Lithium aluminium hydride, 2.4M solution in THF Revision Date 17-Dec-2020 ______________________________________________________________________________________________ depression 4.3. Indication of any immediate medical attention and special treatment needed Notes to Physician Treat symptomatically. Symptoms may be delayed. SECTION 5: FIREFIGHTING MEASURES 5.1. Extinguishing media Suitable Extinguishing Media CO 2, dry chemical, dry sand, alcohol-resistant foam. Water mist may be used to cool closed containers. Extinguishing media which must not be used for safety reasons Water. 5.2. Special hazards arising from the substance or mixture Thermal decomposition can lead to release of irritating gases and vapors. The product causes burns of eyes, skin and mucous membranes. Flammable. Containers may explode when heated. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Hazardous Combustion Products Carbon monoxide (CO), Carbon dioxide (CO2), Hydrogen. 5.3. Advice for firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. Thermal decomposition can lead to release of irritating gases and vapors. SECTION 6: ACCIDENTAL RELEASE MEASURES 6.1. Personal precautions, protective equipment and emergency procedures Ensure adequate ventilation. Use personal protective equipment as required. Evacuate personnel to safe areas. Keep people away from and upwind of spill/leak. Remove all sources of ignition. Take precautionary measures against static discharges. 6.2. Environmental precautions Should not be released into the environment. 6.3. Methods and material for containment and cleaning up Keep in suitable, closed containers for disposal. Soak up with inert absorbent material. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Reacts violently with water: Absorb spill with inert material (e.g. dry sand or earth), then place in a chemical waste container: Keep in suitable, closed containers for disposal 6.4. Reference to other sections Refer to protective measures listed in Sections 8 and 13. SECTION 7: HANDLING AND STORAGE 7.1. Precautions for safe handling ______________________________________________________________________________________________ ACR37732 Page 4 / 12 SAFETY DATA SHEET Lithium aluminium hydride, 2.4M solution in THF Revision Date 17-Dec-2020 ______________________________________________________________________________________________ Wear personal protective equipment/face protection. Do not get in eyes, on skin, or on clothing. Use only under a chemical fume hood. Do not breathe mist/vapors/spray. Do not ingest. If swallowed then seek immediate medical assistance. If peroxide formation is suspected, do not open or move container. Keep away from open flames, hot surfaces and sources of ignition. Use only non-sparking tools. To avoid ignition of vapors by static electricity discharge, all metal parts of the equipment must be grounded. Take precautionary measures against static discharges. Hygiene Measures Handle in accordance with good industrial
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  • Peroxide-Forming Chemicals
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