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Douglas S. Scherr 2. Office A Weill Cornell Medical College Curriculum vitae and Bibliography A. GENERAL INFORMATION 1. Name: Douglas S. Scherr 2. Office address, telephone, fax: Starr 900, Department of Urology The New York Presbyterian Hospital- Weill Medical College of Cornell University 525 East 68th Street New York, NY 10065 Phone: (212) 746-5788 Fax: (212) 746-0975 3. Email: [email protected] B. EDUCATIONAL BACKGROUND 1. Degrees Degree Institution Dates attended Year awarded B.A. Cornell University, Arts & Sciences 8/85-5/89 1989 Ithaca, New York M.D. The George Washington University 7/90-6/94 1994 Medical School Washington, D.C. C. PROFESSIONAL POSITIONS AND EMPLOYMENT Post-doctoral training: 1994-5 Intern, General Surgery The George Washington University Hospital 1995-6 Junior Assistant Resident, General Surgery The George Washington University Hospital Resident in Urology The James Buchanan Brady Department of Urology The New York Hospital-Cornell Medical Center New York, N.Y. 1999-00 Chief Resident in Urology The James Buchanan Brady Department of Urology The New York Hospital-Cornell Medical Center New York, N.Y. 2000-02 Fellow, Urologic Oncology Department of Urology Memorial Sloan Kettering Cancer Center New York, New York Academic positions: 7/01-6/02 Instructor in Urology Department of Urology Weill Medical College of Cornell University New York, N.Y. 7/02-6/08 Assistant Professor of Urology Clinical Director, Urologic Oncology Department of Urology Weill Medical College of Cornell University New York, N.Y. 7/08-Present Associate Professor of Urology Clinical Director, Urologic Oncology Weill Medical College of Cornell University New York, N.Y. 1/03-present Visiting Associate Physician Rockefeller University Hospital Rockefeller University, New York, N.Y. Hospital positions: 07/02-06/08 Assistant Attending Urologist New York-Presbyterian Hospital New York, N.Y. 07/08-present Associate Attending Urologist New York-Presbyterian Hospital New York, N.Y. Other employment: N/A D. LICENSURE, BOARD CERTIFICATION, MALPRACTICE 1. Licensure a. New York Date of issue 6/96 b. Date of last registration 12/09 - 12/11 2. Board Certification American Board of Urology 13173 2/28/03 Re-certified 2010 E. PROFESSIONAL MEMBERSHIPS Member/officer Name of Organization Dates held Diplomat American Board of Urology 2004-Present Member Society of Urologic Oncology 2006-Present Founding Member, Executive Committee, 2006-Present Young Urologic Oncology Society Member, Society for Basic Urological Research 2002-Present Member American Urological Association 2000-Present Member New York Section of AUA, Co-Chair of 2008-Present Valentine Essay Meeting Member Society of University Urologists 1998-2004 Member American Medical Association 1994-Present Lecturer American Austrian Foundation 2000-2004 Member Cancer and Leukemia Group B 2002-2006 (CALGB), GU Core F. HONORS AND AWARDS 1. Name of award Date awarded William Beaumont Medical Research Honor SocietyFirst Prize for Best Original Medical Essay, The William Shafirt Award, The George Washington University School of Medicine. “A crisis of unknown proportion: An empirical analysis of the American medical malpractice system.” 1994 First Prize for Clinical Investigation, Ferdinand C. Valentine Urology Residents Essay Meeting, “BCL-2 and P53 expression in clinically localized prostate cancer as predictive markers for the response to external beam radiotherapy.” 1998 First Prize for Clinical Investigation, Society of University Urology Residents,Annual Chief Resident Meeting, Marietta, Georgia. “Anti-androgen therapy for prostate cancer and the prevention of osteoporosis: The role of DES.” 2000 Second Prize for Clinical Investigation, Ferdinand C. Valentine Urology Residents Essay Meeting, “Collagen Type I Crosslinked N-Telopeptide as a urinary marker for osteoporosis in prostate cancer: The role of Diethylstilbesterol (DES).” 2000 Pfizer, Scholars in Urology Award, Awarded for advancing the scientific and clinical field of urology. 2000 Ferdinand C. Valentine Fellowship for Research in Urology. The New York Academy of Medicine. 2001-2002. Syndecan-1 expression in prostate cancer and the role of p27 in primary prostate epithelial cell transformation. T32 Research Training Grant. Memorial Sloan Kettering Cancer Center. 2000-2002. Edwin Beer Research Award. NY Academy of Medicine. Effective Tumor Immunotherapy in Transitional Cell Carcinoma of the Bladder. 2005-2007 Career Development Award. Kidney Urology Foundation of America. The role of the Pim-1 Oncoprotein in Prostate Carcinogenesis. 2004-2005 Best Video Award. Society of Laparoscopic Surgery. Oncological Outcomes of Robotic Cystectomy. San Francisco, CA August, 2007. G. INSTITUTIONAL/HOSPITAL AFFILIATION 1. Primary Hospital Affiliation NYPH 2. Other Hospital Affiliations: Rockefeller University Hospital H. EMPLOYMENT STATUS 1. Name of Current Employer: Weill Cornell Medical College I. CURRENT AND PAST INSTITUTIONAL RESPONSIBILITIES AND PERCENT EFFORT 1. Teaching: Lecture to 1st year medical students on pelvic anatomy. Teach course to surgical residents on retroperitoneal and pelvic anatomy. Fall semester on a yearly basis since 2004 Lecture to 3rd year medical students on urologic oncology 4x/year. Give Grand Rounds in Urology and General Surgery several times a year. Recurrring since 2002 2. Clinical care : Clinical Director , Urologic Oncology, since 7/02. Treat patients with urologic oncology diseases every week. Perform 8 -10 major surgical cases per week. 3. Administrative duties: a. Weill Medical College Admissions Committee Member since 2007 b. Hospital Committee on DVT Prophylaxis 2007 4. Research: Since 2002 I have maintained an active basice science and clinical research effort. My main focus in the laboratory setting has been in the area of bladder cancer therapeutics and tumor immunology. To be specific, I have worked on developing novel therapies for the intravesical treatment of superficial bladder cancer. My work has focused on a group of compounds called imidazoquinolines. These are Toll Like Receptor antagonists that cause dendritic cell activation with subsequent CD8 lymphocyte activation against bladder tumor antigen. We are about to start a phase I trial in human patients as a result of my pre-clinical work. Further, I am now collaborating with the lab of Dr. Laurie Glimcher to evaluate the role of the ER stress response in bladder cancer. We are working to test an inhibitor of the IRE1/XBP1 pathway for the intravesical treatment of bladder cancer. From a clinical standpoint since 2008, I have focused a great deal of effort in my work developing an multiphoton endoscope. To this end, I have collaborated quite closely with my counterparts at Cornell-Ithaca. In particular, I have worked most closely with Professor Watt W. Webb and Professor Chris Xu in the Department of Applied Engineering and Physics. We now have a prototype available for which we are in the midst of animal testing and hope to move toward human use in the next few years. In addition, I maintain large, robust clinical databases in bladder, prostate and kidney cancer. I was the first physician at NYPH-Weill Cornell to perform a robotic prostatectomy and the first to perform a robotic cystectomy. I have been a pioneer in the development of the field of robotic surgery for bladder cancer and I have the largest, single-surgeon series of robotic cystectomies. J. RESEARCH SUPPORT Current/Past NY Academy of Medicine/Valentine Research Award in Urology Role of p27 in Prostate Epithelial Cell Differentiation PI: Douglas S. Scherr, M.D. Total award: $50,000 Dates: 2001-2003 Kidney Urology Foundation of America Career Development Award The Role of PIM-1 Oncogene in Prostate Carcinogenesis PI: Douglas S. Scherr, M.D. Total Award: $50,000 Dates: 2002-2004 Edwin Beer Research Award Effective Tumor Immunotherapy in Superficial Bladder Cancer Total Award: $40,000/year for 2 years Dates: 2004-2006 3M Pharmaceuticals Phase I Trial of Imiquimod-like Coumpund in the Treatment of Superficial Bladder Cancer PI: Douglas S. Scherr, M.D. Total Award: $112,000 Dates: 2004-2008 Empire Clinical Research Investigator Award.(ECRIP). Development of Direct Medical Applications of Multiphoton Microscopy to Solve Crucial Diagnostic Challenges in Urology: The Use of Two-Photon Tissue Imaging in the Evaluation and Diagnosis of Malignancy. $60,000/yr for 2 years Dates: 2002-2004 NBIB/NIH Bioengineering Partnership Grant. Multiphoton Endoscopy Development. Co-investigator. $2,000,000 Award. PI: Professor Watt W. Webb, PhD Weill Medical College-Cornell University Seed Grant. PI. The development of multiphoton endocsopy in bladder cancer. $50,000. Dates: 2008 Weill Medical College-Cornell University Seed Grant. PI. Microfluidic Chip Development in the diagnosis of Urothelial Cell Carcinoma. $50,000. Dates: 2006 National Institutes of Health Harvard/Michigan/Cornell Prostate Cancer Biomarker Clinical Validation Center PI: Douglas Scherr Performance Period: 2013 – 2014. PI: Douglas Scherr, M.D. 5% effort. Total $35,000 National Center for Advancing Translational Sciences| Metabolomic Profiling of Non-Muscle Invasive Bladder Cancer PI: Douglas Scherr $50,000 per year Performance Period: May 2013 – May 2014 Project Title: Development of Novel Diagnostic Imaging Applications for Prostate Cancer Grant/Protocol Number: Ferdinand C Valentine Fellowship Sponsor: New York Academy of Medicine PI: Douglas Scherr, M.D. Received: 2014-06-17 Amount: $50,000 Term: 1 year Pending: Project Title: Nanoparticles: Imaging and Focal Hyperthermia
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