Schedule as of: November 29, 2013 Schedule is subject to change. 25th Annual Piper Jaffray Healthcare Conference Tuesday, December 3 - Wednesday, December 4, 2013 New York Palace Hotel, New York Tuesday, Track One Track Two Track Three Track Four Track Five Track Six Track Seven December 3 Holmes 1&2 - 4th floor Spellman - 5th floor Hubbard 2 - 5th floor Louis - 4th floor Rutherford - 4th floor Kennedy 1 - 4th floor Kennedy 2 - 4th floor Registration – Villard Foyer, 2nd Floor Public & Private Company 7:30 Private Company Track Continental Breakfast – Reid Salon, 2nd Floor Track

MWI Veterinary Supply, Quality Systems, Inc. Osiris Therapeutics, Galena Biopharma, Inc. 8:00 - 8:30 ResMed Inc. (RMD) Akorn, Inc. (AKRX) 8:10 bioTheranostics, Inc. Inc. (MWIV) (QSII) Inc. (OSIR) (GALE)*

Regeneron 8:30 Good Start Genetics, Inc. SCI Solutions, Inc. Boston Scientific IDEXX Laboratories Inc. , Inc. ArthroCare 8:30 - 9:00 Pharmaceuticals Inc. Corporation (BSX) (IDXX) (JAZZ) Corporation (ARTC) (REGN) 8:50 Neostem, Inc. (NBS)* Accellent, Inc.

Smith & Nephew plc Impax Laboratories, Inc. 9:00 - 9:30 Illumina, Inc. (ILMN) MEDNAX, Inc. (MD) Endocyte, Inc. (ECYT) 9:10 LCA-Vision Inc. (LCAV)* Apollo Endosurgery, Inc. (SNN) (IPXL)

9:30 Venaxis, Inc. (APPY)* California Stem Cell, Inc. St. Jude Medical, Inc. Quest Diagnostics Hill-Rom Holdings, Inc. Cytokinetics, 9:30 - 10:00 Theravance Inc. (THRX) (STJ) Incorporated (DGX) (HRC) Incorporated (CYTK) Repligen Corporation Kadmon Corporation, 9:50 (RGEN)* LLC OncoMed ACADIA Pharmaceuticals Wright Medical Group, Ampio Pharmaceuticals, Curaspan Health Group, 10:00 - 10:30 Mallinckrodt plc (MNK) Pharmaceuticals, Inc. 10:10 Inc. (ACAD) Inc. (WMGI) Inc. (AMPE)* Inc. Home Health Panel (OMED) Moderator: 10:30 GlobeImmune, Inc. Intuity Medical, Inc. Kevin Ellich Globus Medical, Inc. ZIOPHARM 10:30 - 11:00 Exelixis, Inc. (EXEL) Aceto Corp. (ACET) Mauna Kea Technologies (GMED) Oncology, Inc. (ZIOP) 10:50 Metabolon, Inc. SAS (MKEA)*

Orexigen Therapeutics, Vocera Communications, AngioDynamics Inc. 11:00 - 11:30 Henry Schein, Inc. (HSIC) QIAGEN N.V. (QGEN) 11:10 SurModics, Inc. (SRDX)* Evolution1, Inc. Inc. (OREX) Inc. (VCRA) (ANGO)

Solta Medical, Inc. LDR Holding Corporation Five Prime Therapeutics, Nanosphere, Inc. 11:30 Epic Health Services, Inc. 11:30 - 12:00 Zoetis Inc. (ZTS) DexCom, Inc. (DXCM) (SLTM)* (LDRH) Inc. (FPRX) (NSPH) 11:50 IMRIS, Inc. (IMRS)* GetWellNetwork, Inc. 12:00 Visit the Reid Salon-2nd floor or Holmes Foyer-4th floor to pick-up a boxed lunch Integra LifeSciences Halozyme Becton, Dickinson and 12:00 - 12:30 Premier, Inc. (PINC) Holdings Corporation Therapeutics, Inc. 12:10 DepoMed Inc. (DEPO)* ReShape Medical, Inc. Company (BDX) Digital Health Panel (IART) (HALO) Moderator: Thom Pacific Biosciences of 12:30 POZEN Inc. (POZN)* Aptus Endosystems, Inc. Gunderson Mesoblast Limited Pacira Pharmaceuticals, 12:30 - 1:00 Tornier N.V. (TRNX) California, Inc. (MBLTY) Inc. (PCRX) Pain Therapeutics Inc. (PACB) 12:50 Affordable Care, Inc. (PTIE)* Inc. Advisory Board Co. Volcano Corporation Quidel Corporation Discovery Laboratories 1:00 - 1:30 Epizyme, Inc. (EPZM) 1:10 Otonomy, Inc. (BAX) (ABCO) (VOLC) (QDEL) Inc. (DSCO)* 1:30 ViaCyte, Inc. CardioFocus, Inc. Horizon Pharma, Inc. Sunshine Heart, Inc. 1:30 - 2:00Medtronic, Inc. (MDT) AmSurg Corp. (AMSG) Novavax, Inc. (NVAX) Diamedica Inc. (DMA Conventus Orthopaedics, (HZNP) (SSH) 1:50 CN)* Inc.

ScheduleforWednesday,December4,2013Page1of4 Schedule as of: November 29, 2013 Schedule is subject to change. 25th Annual Piper Jaffray Healthcare Conference Tuesday, December 3 - Wednesday, December 4, 2013 New York Palace Hotel, New York Tuesday, Track One Track Two Track Three Track Four Track Five Track Six Track Seven December 3 Holmes 1&2 - 4th floor Spellman - 5th floor Hubbard 2 - 5th floor Louis - 4th floor Rutherford - 4th floor Kennedy 1 - 4th floor Kennedy 2 - 4th floor

Clovis Oncology, Inc. HeartWare International Sunesis Pharmaceuticals, Derma Sciences Inc. 2:00 - 2:30 3D Printing and Additive 2:10 K2M, Inc. HeartFlow Inc. (CLVS) Inc. (HTWR) Inc. (SNSS) (DSCI) Manufacturing Applications in Health Advanced Pain Alexza 2:30 Valeritas, Inc. Care INSYS Therapeutics, Inc. Natus Medical Inc. Management, S.C. 2:30 - 3:00 Cyberonics, Inc. (CYBX) Pharmaceuticals, Inc. Moderator: Matt Miksic (INSY) (BABY) (ALXA) 2:50 Topera, Inc. Awarepoint Corporation

PDL BioPharma, Inc. Acceleron Pharma, Inc. STAAR Surgical 3:00 - 3:30 Abaxis Inc. (ABAX) 3:10 Zyga Technology, Inc. CareCloud Corporation (PDLI) (XLRN) Company (STAA) Big Data Panel Kips Bay Medical, Inc. Threshold 3:30 Cellnovo Limited Moderator: Sean Wieland Insulet Corporation Array BioPharma Inc. Symmetry Medical Inc. (KIPS)* 3:30 - 4:00 Pharmaceuticals, Inc. (PODD) (ARRY) (SMA) On-X Life Technologies, (THLD) 3:50 Quantros, Inc. Inc. Peregrine Anthera Teleflex Incorporated Cantel Medical Corp Computer Programs And Ocera Therapeutics, Inc. 4:00 - 4:30 Pharmaceuticals, Inc. Pharmaceuticals, Inc. 4:10 OmniGuide, Inc. (TFX) (CMN) Systems Inc. (CPSI) (OCRX)* (PPHM) (ANTH)

Sagent Pharmaceuticals, Conatus Pharmaceuticals NanoString Technologies, Mast Therapeutics, RedPath Integrated 4:30 - 5:00 Sorin SpA (SRN IM) 4:30 Ulthera, Inc. Inc. (SGNT) Inc. (CNAT) Inc. (NSTG) Inc. (MSTX) Pathology, Inc.

The follow companies are participating in one-on-one meetings only. Contact your Piper Jaffray representive if interested. Antares Pharma Inc. (ATRS); GenMark Diagnostics, Inc. (GNMK) and Healthways, Inc. (HWAY)

* Public companies presenting in Track 5 will be available for networking in the Reid Room, 2nd floor at a hosted table for up to 2 hours following their presentation.

Key: Biotech companies Speciality Pharma companies Services companies Med Tech companies Tools & Diagnostic companies

PIPER JAFFRAY IS A LEADING INVESTMENT BANK AND ASSET MANAGEMENT FIRM. Piper Jaffray Companies is an investment bank and asset management firm headquartered in Minneapolis with offices across the U.S. and in London, Hong Kong* and Zurich. Securities brokerage and investment banking services are offered in the United States through Piper Jaffray & Co., member NYSE and SIPC, and in Europe through Piper Jaffray Ltd., authorized and regulated by the Financial Conduct Authority. Asset management products and services are offered through three separate investment advisory affiliates registered with the U.S. Securities and Exchange Commission: Advisory Research Inc., Piper Jaffray Investment Management LLC and PJC Capital Partners LLC.

© 2013 Piper Jaffray Companies. 800 Nicollet Mall, Minneapolis, Minnesota 55402-7020.

* License pending

ScheduleforWednesday,December4,2013Page2of4 Schedule as of: November 29, 2013 Schedule is subject to change. 25th Annual Piper Jaffray Healthcare Conference Tuesday, December 3 - Wednesday, December 4, 2013 New York Palace Hotel, New York Wednesday, Track One Track Two Track Three Track Four Track Five Track Six Track Seven December 4 Holmes 1&2 - 4th floor Spellman - 5th floor Hubbard 2 - 5th floor Louis - 4th floor Rutherford - 4th floor Kennedy 1 - 4th floor Kennedy 2 - 4th floor Piper Jaffray Senior Analyst Med Tech Breakfast Roundtable Public & Private Company 6:30 - 7:25 Hosted by: Kevin Ellich, Thom Gunderson, Matt Miksic, Bill Quirk and Brooks West Private Company Track Location: Louis Room, 4th floor, NY Palace. RSVP to your Piper Jaffray representative. Track Registration – Villard Foyer, 2nd Floor 7:30 Continental Breakfast – Reid Salon, 2nd Floor Masimo Corporation Sangamo BioSciences, Oncolytics Biotech Inc. 8:00 - 8:30 Inc. (AGN) ABIOMED, Inc. (ABMD) (MASI) Inc. (SGMO) (ONCY)

Trimel Pharmaceuticals Crescendo Bioscience, 8:30 Cerner Corporation Avanir Pharmaceuticals, GW Pharmaceuticals plc Corp. (TRL CN)* Inc. 8:30 - 9:00 Greatbatch, Inc. (GB) Athersys, Inc. (ATHX) (CERN) Inc. (AVNR) (GWPH) Cell Therapeutics, Inc. miRagen Therapeutics, 8:50 (CTIC)* Inc. Team Health Holdings, Merit Medical Systems, AMN Healthcare Services 9:00 - 9:30 Biomet Inc. (private) Sequenom Inc. (SQNM) Chimerix, Inc. (CMRX) 9:10 Senseonics, Inc. Inc. (TMH) Inc. (MMSI) Inc. (AHS)* Martindale 9:30 Vitals , Inc. Inovio Pharmaceuticals, Pharmaceuticals Ltd. 9:30 - 10:00 C.R. Bard, Inc. (BCR) Cepheid (CPHD) Omnicell, Inc. (OMCL) (SRPT) Inc. (INO) 9:50 Ariosa Diagnostics, Inc. Bioventus LLC

Advanced Surgical MannKind Corporation AcelRx Pharmaceuticals, 10:00 - 10:30 bioMerieux (BIM FP) AtriCure, Inc. (ATRC) 10:10 Civitas Therapeutics Respicardia, Inc. Technology and (MNKD) Inc. (ACRX) Innovation in Medtech Panel 10:30 Histogenics NXThera, Inc. , Inc. Mirati Therapeutics, Inc. 10:30 - 11:00 Moderator: VCA Antech, Inc. (WOOF) Curis Inc. (CRIS) (ACOR) (MRTX) Matt Miksic 10:50 Pfenex Inc. Sonitus Medical Inc.

Alnylam Pharmaceuticals, BioMarin Pharmaceutical Spectranetics Corporation 11:00 - 11:30 VIVUS Inc. (VVUS) LipoScience, Inc. (LPDX) 11:10 Singulex, Inc. Holaira Inc. Inc. (ALNY) Inc. (BMRN) (The) (SPNC)

Integrated Diagnostics Arena Pharmaceuticals, CONMED Corporation Neurocrine Biosciences Cadence Pharmaceuticals, Vanda Pharmaceuticals, 11:30 Asante Solutions, Inc. 11:30 - 12:00 Inc. Inc. (ARNA) (CNMD) Inc. (NBIX) Inc. (CADX) Inc. (VNDA)

11:50 PerfectServe, Inc. ISTO Technologies, Inc. 12:00 Visit the Reid Salon-2nd floor or Holmes Foyer-4th floor to pick-up a boxed lunch

Patterson Companies Inc. Thoratec Corporation Anacor Pharmaceuticals, Vascular Solutions, Inc. RXi Pharmaceuticals 12:00 - 12:30 12:10 Teladoc, Inc. CareKinesis, Inc. (PDCO) (THOR) Inc. (ANAC) (VASC) Corporation (RXII)

Pinnacle Treatment Medicines Company (The) NxStage Medical, Inc. Achillion Pharmaceuticals, Geron Corporation 12:30 Minnetronix, Inc. 12:30 - 1:00 Cutera, Inc. (CUTR) Centers, Inc. (MDCO) (NXTM) Inc. (ACHN) (GERN) 12:50 Ambrx, Inc. Imthera Medical, Inc.

Envision Healthcare Accuray Incorporated Rigel Pharmaceuticals BioDelivery Sciences IntelliPharmaCeutics Heat Biologics, Inc. 1:00 - 1:30 1:10 MC10 Holdings, Inc. (EVHC) (ARAY) (RIGL) International, Inc. (BDSI) International Inc. (HTBX)*

ScheduleforWednesday,December4,2013Page3of4 Schedule as of: November 29, 2013 Schedule is subject to change. 25th Annual Piper Jaffray Healthcare Conference Tuesday, December 3 - Wednesday, December 4, 2013 New York Palace Hotel, New York Wednesday, Track One Track Two Track Three Track Four Track Five Track Six Track Seven December 4 Holmes 1&2 - 4th floor Spellman - 5th floor Hubbard 2 - 5th floor Louis - 4th floor Rutherford - 4th floor Kennedy 1 - 4th floor Kennedy 2 - 4th floor 1:30 myoscience, Inc. Capricor, Inc. Novadaq Technologies Emergent BioSolutions Aratana Therapeutics, Inc. Arrowhead Research Corp. 1:30 - 2:00 PerkinElmer Inc. (PKI) Cormatrix Cardiovascular, Inc. (NVDQ) Inc. (EBS) (PETX) (ARWR) 1:50 Monteris Medical, Inc. Inc.

Fluidigm Corporation Hyperion Therapeutics, XOMA Corporation Baxano Surgical, Inc. Highland Therapeutics 2:00 - 2:30 ICU Medical, Inc. (ICUI) 2:10 TearScience, Inc. (FLDM) Inc. (HPTX) (XOMA) (BAXS) Inc.

2:30 Cempra, Inc. (CEMP)* Sonendo, Inc. BioCryst Pharmaceuticals, Unilife Corporation (UNS Cytos Biotechnology AG 2:30 - 3:00 Endologix Inc. (ELGX) No company presentation Inc. (BCRX) AU) (CYTN SW) 2:50 KLOX Technologies Inc. No company presentation

Supernus Alphatec Holdings, Inc. Idera Pharmaceuticals, 3:00 - 3:30 CryoLife, Inc. (CRY) Pharmaceuticals, Inc. Alcobra Ltd. (ADHD) 3:10 Virobay Inc. No company presentation (ATEC) Inc. (IDRA) (SUPN) Organovo Holdings, Inc. Hansen Medical, Inc. Onconova Therapeutics, 3:30 - 4:00 TrovaGene, Inc. (TROV) Uroplasty, Inc. (UPI) (ONVO) (HNSN) Inc. (ONTX)

Technical Research Discussion Palatin Technologies, Inc. TherapeuticsMD, Inc. 4:00 - 4:30 Craig Johnson, Sr Analyst, No company presentation No company presentation (PTN) (TXMD) Technical Research, Piper Jaffray & Co.

The follow companies are participating in one-on-one meetings only. Contact your Piper Jaffray representive if interested. Antares Pharma Inc. (ATRS); GenMark Diagnostics, Inc. (GNMK) and Healthways, Inc. (HWAY)

* Public companies presenting in Track 5 will be available for networking in the Reid Room, 2nd floor at a hosted table for up to 2 hours following their presentation.

Key: Biotech companies Speciality Pharma companies Services companies Med Tech companies Tools & Diagnostic companies

PIPER JAFFRAY IS A LEADING INVESTMENT BANK AND ASSET MANAGEMENT FIRM. Piper Jaffray Companies is an investment bank and asset management firm headquartered in Minneapolis with offices across the U.S. and in London, Hong Kong* and Zurich. Securities brokerage and investment banking services are offered in the United States through Piper Jaffray & Co., member NYSE and SIPC, and in Europe through Piper Jaffray Ltd., authorized and regulated by the Financial Conduct Authority. Asset management products and services are offered through three separate investment advisory affiliates registered with the U.S. Securities and Exchange Commission: Advisory Research Inc., Piper Jaffray Investment Management LLC and PJC Capital Partners LLC.

© 2013 Piper Jaffray Companies. 800 Nicollet Mall, Minneapolis, Minnesota 55402-7020.

* License pending

ScheduleforWednesday,December4,2013Page4of4