Molecular Imagegguided Theranostic and Personali<Ed Medicine

Total Page:16

File Type:pdf, Size:1020Kb

Molecular Imagegguided Theranostic and Personali<Ed Medicine Journal of Biomedicine and Biotechnology 1.'%7.#4 /#)'g 7+&'&*'4#0156+% #0&'4510#.+<'&'&+%+0' Guest Editors: David J. Yang, Hong Zhang, Mei Tian, Carrio Ignasi, Zhen Cheng, and Lie-Hang Shen Molecular Image-Guided Theranostic and Personalized Medicine Journal of Biomedicine and Biotechnology Molecular Image-Guided Theranostic and Personalized Medicine Guest Editors: David J. Yang, Hong Zhang, Mei Tian, Carrio Ignasi, Zhen Cheng, and Lie-Hang Shen Copyright © 2011 Hindawi Publishing Corporation. All rights reserved. This is a special issue published in volume 2011 of “Journal of Biomedicine and Biotechnology.” All articles are open access articles distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Editorial Board The editorial board of the journal is organized into sections that correspond to the subject areas covered by the journal. Agricultural Biotechnology Guihua H. Bai, USA Hari B. Krishnan, USA B. C. Saha, USA Christopher P. Chanway, Canada Carol A. Mallory-Smith, USA Mariam B. Sticklen, USA Ravindra N. Chibbar, Canada Dennis P. Murr, Canada Chiu-Chung Young, Taiwan Ian Godwin, Australia Rodomiro Ortiz, Mexico Animal Biotechnology E. S. Chang, USA Thomas A. Hoagland, USA Lawrence Reynolds, USA Hans H. Cheng, USA Tosso Leeb, Switzerland Lawrence B. Schook, USA Bhanu P. Chowdhary, USA James D. Murray, USA Mari A. Smits, The Netherlands Noelle E. Cockett, USA Anita M. Oberbauer, USA Leon Spicer, USA Peter Dovc, Slovenia Jorge A. Piedrahita, USA J. Verstegen, USA Scott C. Fahrenkrug, USA Daniel Pomp, USA Matthew B. Wheeler, USA Dorian J. Garrick, USA Kent M. Reed, USA Kenneth L. White, USA Biochemistry Robert Blumenthal, USA Hicham Fenniri, Canada Richard D. Ludescher, USA David Ronald Brown, UK Nick V. Grishin, USA George Makhatadze, USA Saulius Butenas, USA J. Guy Guillemette, Canada Leonid Medved, USA Vittorio Calabrese, Italy Paul W. Huber, USA Susan A. Rotenberg, USA F. Castellino, USA Chen-Hsiung Hung, Taiwan Jason Shearer, USA Roberta Chiaraluce, Italy Michael Kalafatis, USA Andrei Surguchov, USA D. M. Clarke, Canada B. E. Kemp, Australia John B. Vincent, USA Francesca Cutruzzola,` Italy Phillip E. Klebba, USA Yujun George Zheng, USA Paul W. Doetsch, USA Wen-Hwa Lee, USA Bioinformatics T. Akutsu, Japan Stavros J. Hamodrakas, Greece Florencio Pazos, Spain Miguel A. Andrade, Germany Paul Harrison, USA Zhirong Sun, China Mark Y. Borodovsky, USA George Karypis, USA Ying Xu, USA Rita Casadio, Italy Jack A. Leunissen, The Netherlands A. Zelikovsky, USA Artem Cherkasov, Canada Guohui Lin, Canada Albert Zomaya, Australia David Corne, UK Satoru Miyano, Japan Sorin Draghici, USA Zoran Obradovic, USA Biophysics Miguel Castanho, Portugal Ali A. Khraibi, Saudi Arabia S. B. Petersen, Denmark P. Bryant Chase, USA Rumiana Koynova, USA Peter Schuck, USA Kuo-Chen Chou, USA Serdar Kuyucak, Australia Claudio M. Soares, Portugal Rizwan Khan, India Jianjie Ma, USA Cell Biology Omar Benzakour, France Xudong Huang, USA Michael Sheetz, USA Sanford I. Bernstein, USA Anton M. Jetten, USA JamesL.Sherley,USA Phillip I. Bird, Australia Seamus J. Martin, Ireland G. S. Stein, USA Eric Bouhassira, USA Manuela Martins-Green, USA Richard Tucker, USA Mohamed Boutjdir, USA Shoichiro Ono, USA Thomas van Groen, USA Chung-Liang Chien, Taiwan George Perry, USA Andre Van Wijnen, USA Richard Gomer, USA M. Piacentini, Italy Steve Winder, UK Paul J. Higgins, USA George E. Plopper, USA Chuanyue Wu, USA Pavel Hozak, Czech Republic Lawrence Rothblum, USA Bin-Xian Zhang, USA Genetics Adewale Adeyinka, USA J. Spencer Johnston, USA Raj S. Ramesar, South Africa Claude Bagnis, France M. Ilyas Kamboh, USA Elliot D. Rosen, USA J. Birchler, USA Feige Kaplan, Canada Dharambir K. Sanghera, USA Susan Blanton, USA Manfred Kayser, The Netherlands Michael Schmid, Germany BarryJ.Byrne,USA Brynn Levy, USA Markus Schuelke, Germany R. Chakraborty, USA Xiao Jiang Li, USA Wolfgang Arthur Schulz, Germany Domenico Coviello, Italy Thomas Liehr, Germany Jorge Sequeiros, Portugal Sarah H. Elsea, USA JamesM.Mason,USA Mouldy Sioud, Norway Celina Janion, Poland Mohammed Rachidi, France Rongjia Zhou, China Genomics Vladimir Bajic, Saudi Arabia Vladimir Larionov, USA Yasushi Okazaki, Japan Margit Burmeister, USA Thomas Lufkin, Singapore Gopi K. Podila, USA Settara Chandrasekharappa, USA Joakim Lundeberg, Sweden Momiao Xiong, USA Yataro Daigo, Japan John L. McGregor, France J. Spencer Johnston, USA John V. Moran, USA Immunology Hassan Alizadeh, USA James D. Gorham, USA Kanury V. S. Rao, India Peter Bretscher, Canada Silvia Gregori, Italy Yair Reisner, Israel Robert E. Cone, USA Thomas Griffith, USA HarryW.Schroeder,USA Terry L. Delovitch, Canada Young S. Hahn, USA Wilhelm Schwaeble, UK Anthony L. DeVico, USA Dorothy E. Lewis, USA Nilabh Shastri, USA Nick Di Girolamo, Australia Bradley W. McIntyre, USA Yufang Shi, China Don Mark Estes, USA R. Mosley, USA Piet Stinissen, Belgium Soldano Ferrone, USA Marija Mostarica-Stojkovic,´ Serbia Hannes Stockinger, Austria Jeffrey A. Frelinger, USA Hans Konrad Muller, Australia J. W. Tervaert, The Netherlands John Robert Gordon, Canada Ali Ouaissi, France Graham R. Wallace, UK Microbial Biotechnology Jozef Anne,´ Belgium Peter Coloe, Australia Angela Sessitsch, Austria Yoav Bashan, Mexico Daniele Daffonchio, Italy Effie Tsakalidou, Greece Marco Bazzicalupo, Italy Han de Winde, The Netherlands J. Wiegel, USA Nico Boon, Belgium Yanhe Ma, China Luca Simone Cocolin, Italy Bernd H. A. Rehm, New Zealand Microbiology D. Beighton, UK Gad Frankel, UK Isabel Sa-Correia,´ Portugal Steven R. Blanke, USA Roy Gross, Germany P. L. C. Small, USA Stanley Brul, The Netherlands Hans-Peter Klenk, Germany Lori Snyder, UK IsaacK.O.Cann,USA Tanya Parish, UK Michael Thomm, Germany Peter Dimroth, Switzerland Gopi K. Podila, USA H. C. van der Mei, The Netherlands Stephen K. Farrand, USA Frederick D. Quinn, USA Schwan William, USA Alain Filloux, UK Didier A. Raoult, France Molecular Biology Rudi Beyaert, Belgium Wuyuan Lu, USA William S. Trimble, Canada Michael Bustin, USA Patrick Matthias, Switzerland Lisa Wiesmuller, Germany Douglas Cyr, USA John L. McGregor, France Masamitsu Yamaguchi, Japan K. Iatrou, Greece S. L. Mowbray, Sweden Lokesh Joshi, Ireland Elena Orlova, UK David W. Litchfield, Canada Yeon-Kyun Shin, USA Oncology Colin Cooper, UK Steve B. Jiang, USA P. J. Oefner, Germany F. M. J. Debruyne, The Netherlands Daehee Kang, Republic of Korea Allal Ouhtit, USA Nathan Ames Ellis, USA Abdul R. Khokhar, USA Frank Pajonk, USA Dominic Fan, USA Rakesh Kumar, USA Waldemar Priebe, USA Gary E. Gallick, USA Macus Tien Kuo, USA F. C. Schmitt, Portugal DailaS.Gridley,USA Eric W. Lam, UK Sonshin Takao, Japan Xin-yuan Guan, Hong Kong Sue-Hwa Lin, USA Ana Maria Tari, USA Anne Hamburger, USA Kapil Mehta, USA Henk G. Van Der Poel, The Netherlands Manoor Prakash Hande, Singapore Orhan Nalcioglu, USA Haodong Xu, USA Beric Henderson, Australia Vincent C. O. Njar, USA David J. Yang, USA Pharmacology Abdel A. Abdel-Rahman, USA Ayman El-Kadi, Canada Kennerly S. Patrick, USA M. Badr, USA Jeffrey Hughes, USA Vickram Ramkumar, USA Stelvio M. Bandiera, Canada Kazim Husain, USA Michael J. Spinella, USA Ronald E. Baynes, USA Farhad Kamali, UK Quadiri Timour, France R. Keith Campbell, USA Michael Kassiou, Australia Todd W. Vanderah, USA Hak-Kim Chan, Australia Joseph J. McArdle, USA Val J. Watts, USA Michael D. Coleman, UK Mark J. McKeage, New Zealand David J. Waxman, USA J. Descotes, France Daniel T. Monaghan, USA Dobromir Dobrev, Germany T. Narahashi, USA Plant Biotechnology P. L. Bhalla, Australia Liwen Jiang, Hong Kong Ralf Reski, Germany J. R. Botella, Australia Pulugurtha Bharadwaja Kirti, India Sudhir Kumar Sopory, India Elvira Gonzalez De Mejia, USA Yong Pyo Lim, Republic of Korea H. M. Haggman,¨ Finland Gopi K. Podila, USA Toxicology Michael Aschner, USA Youmin James Kang, USA Kenneth Turteltaub, USA Michael L. Cunningham, USA M. Firoze Khan, USA Brad Upham, USA Laurence D. Fechter, USA Pascal Kintz, France Hartmut Jaeschke, USA R. S. Tjeerdema, USA Virology Nafees Ahmad, USA Fred Kibenge, Canada Ralf Wagner, Germany Edouard Cantin, USA Fenyong Liu, USA Jianguo Wu, China Ellen Collisson, USA Eric´ Rassart, Canada Decheng Yang, Canada Kevin M. Coombs, Canada Gerald G. Schumann, Germany Jiing-Kuan Yee, USA Norbert K. Herzog, USA Y.-C. Sung, Republic of Korea Xueping Zhou, China Tom Hobman, Canada Gregory Tannock, Australia Wen-Quan Zou, USA Shahid Jameel, India Contents Molecular Image-Guided Theranostic and Personalized Medicine, Hong Zhang, Mei Tian, Carrio Ignasi, Zhen Cheng, Lie-Hang Shen, and David J. Yang Volume 2011, Article ID 673697, 1 page The Role of Molecular Imaging in the Diagnosis and Management of Neuropsychiatric Disorders, Lie-Hang Shen, Yu-Chin Tseng, Mei-Hsiu Liao, and Ying-Kai Fu Volume 2011, Article ID 439397, 11 pages Synthesis and Evaluation of Amino Acid-Based Radiotracer 99mTc-N4-AMT for Breast Cancer Imaging, Fan-Lin Kong, Mohammad S. Ali, Yinhan Zhang, Chang-Sok Oh, Dong-Fang Yu, Mithu Chanda, and David J. Yang Volume 2011, Article ID 276907, 7 pages Technetium-99m-Labeled Autologous Serum Albumin: A Personal-Exclusive Source of Serum Component, Yuh-Feng Wang, Yi-Chun Chen, Dian-Kun Li, and Mei-Hua Chuang Volume 2011, Article ID 413802, 7 pages Molecular Imaging, Pharmacokinetics, and Dosimetry of 111In-AMBA in Human Prostate Tumor-Bearing Mice, Chung-Li Ho, I-Hsiang Liu, Yu-Hsien Wu, Liang-Cheng Chen, Chun-Lin Chen, Wan-Chi Lee, Cheng-Hui Chuang,
Recommended publications
  • Download Author Version (PDF)
    Chemical Science Accepted Manuscript This is an Accepted Manuscript, which has been through the Royal Society of Chemistry peer review process and has been accepted for publication. Accepted Manuscripts are published online shortly after acceptance, before technical editing, formatting and proof reading. Using this free service, authors can make their results available to the community, in citable form, before we publish the edited article. We will replace this Accepted Manuscript with the edited and formatted Advance Article as soon as it is available. You can find more information about Accepted Manuscripts in the Information for Authors. Please note that technical editing may introduce minor changes to the text and/or graphics, which may alter content. The journal’s standard Terms & Conditions and the Ethical guidelines still apply. In no event shall the Royal Society of Chemistry be held responsible for any errors or omissions in this Accepted Manuscript or any consequences arising from the use of any information it contains. www.rsc.org/chemicalscience Page 1 of 5 Chemical Science Uptake of one and two molecules of CO2 by the molybdate dianion: a soluble, molecular oxide model system for carbon dioxide fixation†‡ Ioana Knopf,a Takashi Ono,a Manuel Temprado,b Daniel Tofan,a and Christopher C. Cummins ∗;a Received Xth XXXXXXXXXX 20XX, Accepted Xth XXXXXXXXX 20XX First published on the web Xth XXXXXXXXXX 200X DOI: 10.1039/b000000x 2− Tetrahedral [MoO4] readily binds CO2 at room tem- herein we report the finding that molybdate absorbs not just perature to produce a robust monocarbonate complex, one but two equivalents of CO2 (the second, reversibly) to- 2 2− [MoO3(k -CO3)] , that does not release CO2 even at gether with complete characterization including single-crystal modestly elevated temperatures (up to 56 ◦C in solution X-ray diffraction studies of the resulting mono- and dicarbon- and 70 ◦C in the solid state).
    [Show full text]
  • Divergent Synthesis of Cyclopropane-Containing Fragments and Lead-Like Compounds for Drug Discovery
    Divergent Synthesis of Cyclopropane-Containing Fragments and Lead-Like Compounds for Drug Discovery A Thesis submitted by Stephen John Chawner In partial fulfilment of the requirement for the degree of DOCTOR OF PHILOSOPHY Department of Chemistry Imperial College London South Kensington London SW7 2AZ United Kingdom 2017 1 I confirm that the work presented within this document is my own. Clear acknowledgement has been made when referring to the work of others, or where help has been received. The copyright of this thesis rests with the author and is made available under a Creative Commons Attribution Non-Commercial No Derivatives licence. Researchers are free to copy, distribute or transmit the thesis on the condition that they attribute it, that they do not use it for commercial purposes and that they do not alter, transform or build upon it. For any reuse or redistribution, researchers must make clear to others the licence terms of this work. 2 Acknowledgements Firstly, I would like to thank Imperial College London and Eli Lilly whose combined generosity through a CASE award made my PhD financially possible. I would like to thank my academic supervisor Dr James Bull for providing me with the opportunity to undertake a PhD in his group. I am grateful for the chemistry knowledge that he has shared, his encouragement to present at conferences and the freedom to follow new project ideas. In addition to funding, the CASE award provided me with the opportunity to collaborate with Dr Manuel Cases-Thomas at Erl Wood. Manuel was a constant source of enthusiasm throughout my PhD and has been a joy to work with.
    [Show full text]
  • (+)-Belactosin A
    Total Synthesis of (+)-Belactosin A A thesis submitted by James Nicholas Scutt in partial fulfilment of the requirements for the degree of Doctor of Philosophy TT MU r u * 1630444 Heilbron Laboratory Department of Chemistry Imperial College London London SW7 2AY January 2005 Contents Contents 2 Abstract 4 Acknowledgements 5 Abbreviations 6 Stereochemical notation 9 Chapter 1 - Introduction 10 1.1 Isolation and structure of (+)-belactosin A 11 1.2 Proteasome inhibition 12 1.2.1 Biological activity of (+)-belactosin A 12 1.3 Review of previous work 14 1.3.1 De Meijere's synthesis of(2S/R*, I'R, 2'5)-AcpAla 14 1.3.2 Synthesis of a related (isomeric) p-lactone 20 1.4 Recent synthetic work 22 1.4.1 De Meijere's synthesis of AcpAla (all isomers) 23 1.4.2 Vedaras' synthesis of (2S, 1 'R, 2'S)-AcpAla 25 1.4.3 De Meijere's total synthesis of (+)-belactosin A 26 Chapter 2 - Results and discussion 30 2.1 Project aims 31 2.1.1 Synthesis of trans-AcpAla isomers - overview of synthetic strategy 32 2.2 Boronic ester route 34 2.2.1 Introduction 34 2.2.2 Synthesis of cyclopropyl boronic esters 36 2.2.3 Amination of cyclopropyl boronic esters 39 2.3 Epoxide cyclopropanation route 43 2.3.1 Introduction 43 2.3.2. Stereoselectivity and stereospecificity 47 2.3.3 Wadsworth-Emmons aminocyclopropanation 49 2.3.4 Optimisation of Wadsworth-Emmons cyclopropanation 53 2.3.5 Increasing reactivity 59 2.3.6 Room temperature Wadsworth-Emmons cyclopropanation 62 2.3.7 Horner cyclopropanation 64 2.3.8 Asymmetric Wadsworth-Emmons cyclopropanation 65 2.4 Conversion of cyclopropyl
    [Show full text]
  • The Generation and Reactivity of Functionalised Organozinc Carbenoids for Cyclopropane Synthesis
    The Generation and Reactivity of Functionalised Organozinc Carbenoids for Cyclopropane Synthesis A Thesis Presented by Laure Jerome In Partial Fulfilment of the Requirements for the Award of the Degree of DOCTOR OF PHILOSOPHY OF THE UNIVERSITY COLLEGE LONDON Christopher Ingold Laboratories Department of Chemistry University of London London WC1H 0AJ May 2009 1 Declaration Declaration I, Laure Jerome, confirm that the work presented in this thesis is, to the best of my knowledge, my own. Where information has been derived from other sources, I confirm that this has been indicated in the thesis. 2 Abstract Abstract This thesis describes the generation and reactivity of functionalised organozinc carbenoids for cyclopropane synthesis with alkenes. In the introductory chapter, a brief overview of the different methods for preparation of heteroatom-functionalised cyclopropanes is presented, including [2+1] cycloaddition reactions using a carbene or carbenoid as a cyclopropanating agent with an alkene, ionic stepwise methods, and chemical modifications from existing cyclopropanes. The remainder of this chapter then focuses on previous work within our own group in this area. The second chapter presents the results obtained from different areas of research in the present study, the first of these being a deeper understanding and extension of the research work undertaken by my predecessor for the development of the cyclopropanation reaction using an “amidoorganozinc” carbenoid derived from N,N diethoxymethyloxazolidinones derivatives in the presence of a source of zinc and chlorotrimethylsilane. Thus, the chemoselectivity and stereoselectivtity of the reaction were fully studied, and a quadrant model was constructed to rationalise the stereochemistry of the products obtained.
    [Show full text]
  • Safety Data Sheet: Di-Tert-Butyl Dicarbonate
    safety data sheet according to Regulation (EC) No. 1907/2006 (REACH), amended by 2015/830/EU Di-tert-butyl dicarbonate ≥98 % article number: 6985 date of compilation: 03.11.2016 Version: 1.0 en SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1 Product identifier Identification of the substance Di-tert-butyl dicarbonate Article number 6985 Registration number (REACH) This information is not available. EC number 246-240-1 CAS number 24424-99-5 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses: laboratory chemical 1.3 Details of the supplier of the safety data sheet Carl Roth GmbH + Co KG Schoemperlenstr. 3-5 D-76185 Karlsruhe Germany Telephone: +49 (0) 721 - 56 06 0 Telefax: +49 (0) 721 - 56 06 149 e-mail: [email protected] Website: www.carlroth.de Competent person responsible for the safety data : Department Health, Safety and Environment sheet e-mail (competent person) : [email protected] 1.4 Emergency telephone number Emergency information service Poison Centre Munich: +49/(0)89 19240 SECTION 2: Hazards identification 2.1 Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 (CLP) Classification acc. to GHS Section Hazard class Hazard class and cat- Hazard egory state- ment 2.6 flammable liquid (Flam. Liq. 3) H226 3.1I acute toxicity (inhal.) (Acute Tox. 1) H330 3.2 skin corrosion/irritation (Skin Irrit. 2) H315 3.3 serious eye damage/eye irritation (Eye Irrit. 2) H319 3.4S skin sensitisation (Skin Sens. 1A) H317 Malta (en) Page 1 / 13 safety data sheet according to Regulation (EC) No.
    [Show full text]
  • Safety Data Sheet
    Safety Data Sheet 1. IDENTIFICATION OF THE MATERIAL AND SUPPLIER Product identifier Product name : Velcorin® Hazardous ingredients : dimethyl dicarbonate [4525-33-1] REACH substance name : dimethyl dicarbonate Other names : Dimethyl dicarbonate (DMDC), dimethyl pyrocarbonate (DMPC), pyrocarbonic acid dimethyl ester Recommended use of the chemical and restrictions on use Suitable use : Microbial control agent Supplier/Manufacturer : LANXESS, Germany Telephone +49 214 3065109 Distributor : Victus International Pty Ltd 3 Slough Road ALTONA VIC 3018 AUSTRALIA Telephone : +61 3 9315 0011 Facsimile : +61 3 9315 0066 Emergency Telephone : 1300 VICTUS (1300 842887) David Lueddeke 0418 524 573 2. HAZARDS IDENTIFICATION Classification according to GHS Acute toxicity, oral Hazard Category 4 Acute toxicity, inhalation Hazard Category 2 Skin corrosion/irritation Hazard Category 1B Label Elements Signal Word : Danger dimethyl dicarbonate [4525-33-1] Page 1 of 12 Date of Issue: 13/01/2017 Dimethyl Dicarbonate Hazard Statements H302 : Harmful if swallowed H330 : Fatal if inhaled H314 : Causes severe skin burns and eye damage Additional warning phrases: Not applicable Precautionary statement Prevention P260 : Do not breathe dust/fume/gas/mist/vapours/spray. P270 : Do not eat, drink or smoke when using this product. P271 : Use only outdoors or in a well-ventilated area. P280 : Wear protective gloves/protective clothing/eye protection/face protection. P284 : Wear respiratory protection. Response P303+P361+P353 : IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. P304+P340 : IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305+P351+P338 : IF IN EYES: Rinse cautiously with water for several minutes.
    [Show full text]
  • 30 Part 172—Food Additives
    Pt. 172 21 CFR Ch. I (4–1–12 Edition) shall be furnished in the form specified Subpart D—Special Dietary and Nutritional in §§ 171.1 and 171.100 for submitting pe- Additives titions. 172.310 Aluminum nicotinate. [42 FR 14491, Mar. 15, 1977, as amended at 42 172.315 Nicotinamide-ascorbic acid complex. FR 15674, Mar. 22, 1977] 172.320 Amino acids. 172.325 Bakers yeast protein. 172.330 Calcium pantothenate, calcium chlo- PART 172—FOOD ADDITIVES PER- ride double salt. MITTED FOR DIRECT ADDITION TO 172.335 D-Pantothenamide. FOOD FOR HUMAN CONSUMP- 172.340 Fish protein isolate. 172.345 Folic acid (folacin). TION 172.350 Fumaric acid and salts of fumaric acid. Subpart A—General Provisions 172.365 Kelp. 172.370 Iron-choline citrate complex. Sec. 172.372 N-Acetyl-L-methionine. 172.5 General provisions for direct food ad- 172.375 Potassium iodide. ditives. 172.379 Vitamin D2. 172.380 Vitamin D3. Subpart B—Food Preservatives 172.385 Whole fish protein concentrate. 172.395 Xylitol. 172.105 Anoxomer. 172.399 Zinc methionine sulfate. 172.110 BHA. 172.115 BHT. Subpart E—Anticaking Agents 172.120 Calcium disodium EDTA. 172.410 Calcium silicate. 172.130 Dehydroacetic acid. 172.430 Iron ammonium citrate. 172.133 Dimethyl dicarbonate. 172.480 Silicon dioxide. 172.135 Disodium EDTA. 172.490 Yellow prussiate of soda. 172.140 Ethoxyquin. 172.145 Heptylparaben. Subpart F—Flavoring Agents and Related 172.150 4-Hydroxymethyl-2,6-di-tert-butyl- Substances phenol. 172.510 Natural flavoring substances and 172.155 Natamycin (pimaricin). natural substances used in conjunction 172.160 Potassium nitrate.
    [Show full text]
  • Silicon Electrolyte Interface Stabilization (Seista) Final Progress Report FY19
    Silicon Electrolyte Interface Stabilization (SEISta) Final Progress Report FY19 Anthony Burrell National Renewable Energy Laboratory 15013 Denver West Parkway Golden, CO 80401 Phone: (303) 384-6666 E-mail: [email protected] Brian Cunningham, DOE-EERE-VTO Program Manager Hybrid Electric Systems, Battery R&D Phone: (202) 586-8055 E-mail: [email protected] Table of Contents Page Overview ................................................................................................................................................ 1 SEISta Milestone FY19 .......................................................................................................................... 4 Part 1. Studies of SiO2 Interfaces ........................................................................................................... 5 Part 2. Origins of Si/Electrolyte Interface Stability .............................................................................. 41 Part 3. The Soluble Species.................................................................................................................. 73 Project Introduction This report documents the Silicon Electrolyte Interface Stabilization team’s approach in 1) characterizing the early-stage silicon solid-electrolyte interphase (SEI) including progress on identifying the specific reaction pathways present in the formation of the SEI layer, and 2) establishing a procedure for measuring SEI growth rate at fixed potentials and different cycling regimes. Silicon is a viable alternative
    [Show full text]
  • Safety Data Sheet
    Print Date: 02/05/2019 SDS SAFETY DATA SHEET Oakwood Products, Inc 730 Columbia HWY N Estill, SC 29918 www.oakwoodchemical.com Phone Numbers: Product Information 803­739­8800 Transportation Emergency 800­451­8346 Outside the USA 760­602­8700 MATERIAL IDENTIFICATION NAME: Di­tert­butyl dicarbonate CAS#: [24424­99­5] CAT#: 021896 For R&D use only. HAZARDS IDENTIFICATION GHS Classification Flammable liquids (Category 2) Acute toxicity, dermal (Category 4) Acute toxicity, inhalation (Category 4) GHS Label elements, including precautionary statements Pictograms Signal Word Danger Hazard Statement(s) H225 Highly Flammable liquid and vapour H312 Harmful in contact with skin H332 Harmful if inhaled Precautionary Statement(s) P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P280 Wear protective gloves/protective clothing/eye protection/face protection. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. COMPOSITION/INFORMATION ON INGREDIENTS Synonyms : Di­tert­butyl pyrocarbonate, Boc anhydride Di-tert-butylFormula dicarbonate : C10H18O5 Page 1 of 6 Molecular Weight : 218.25 g/mol CAS Description Concentration 24424­99­5 Di­tert­butyl dicarbonate 99% FIRST AID MEASURES In case of eye contact Immediately flush eyes with running water for at least 15 minutes while keeping eyes open. Seek medical attention. In case of skin contact Wash thoroughly with soap and plenty of water. Seek medical attention. If inhaled Remove victim from source of exposure to fresh air. If breathing is difficult, administer oxygen. Seek medical attention. If swallowed Do not induce vomiting. Give water to victim to drink.
    [Show full text]
  • New Trends in the Conversion of CO2 to Cyclic Carbonates
    catalysts Review New Trends in the Conversion of CO2 to Cyclic Carbonates Erivaldo J.C. Lopes, Ana P.C. Ribeiro * and Luísa M.D.R.S. Martins * Centro de Química Estrutural and Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal; [email protected] * Correspondence: [email protected] (A.P.C.R.); [email protected] (L.M.D.R.S.M.); Tel.: +351-21-841-9201 (A.P.C.R.); +351-21-841-9264 (L.M.D.R.S.M.) Received: 1 April 2020; Accepted: 26 April 2020; Published: 27 April 2020 Abstract: This work concerns recent advances (mainly in the last five years) in the challenging conversion of carbon dioxide (CO2) into fine chemicals, in particular to cyclic carbonates, as a meaningful measure to reduce CO2 emissions in the atmosphere and subsequent global warming effects. Thus, efficient catalysts and catalytic processes developed to convert CO2 into different chemicals towards a more sustainable chemical industry are addressed. Cyclic carbonates can be produced by different routes that directly, or indirectly, use carbon dioxide. Thus, recent findings on CO2 cycloaddition to epoxides as well as on its reaction with diols are reviewed. In addition, indirect sources of carbon dioxide, such as urea, considered a sustainable process with high atom economy, are also discussed. Reaction mechanisms for the transformations involved are also presented. Keywords: carbon dioxide; cyclic carbonate; diol; epoxide; catalysis; CO2 conversion 1. Introduction Modern life is sustained by an unremitting stream of energy delivered to final users as fuels, electricity and heat.
    [Show full text]
  • EAFUS: a Food Additive Database
    U. S. Food and Drug Administration Center for Food Safety and Applied Nutrition Office of Premarket Approval EAFUS: A Food Additive Database This is an informational database maintained by the U.S. Food and Drug Administration (FDA) Center for Food Safety and Applied Nutrition (CFSAN) under an ongoing program known as the Priority-based Assessment of Food Additives (PAFA). It contains administrative, chemical and toxicological information on over 2000 substances directly added to food, including substances regulated by the U.S. Food and Drug Administration (FDA) as direct, "secondary" direct, and color additives, and Generally Recognized As Safe (GRAS) and prior-sanctioned substances. In addition, the database contains only administrative and chemical information on less than 1000 such substances. The more than 3000 total substances together comprise an inventory often referred to as "Everything" Added to Food in the United States (EAFUS). This list of substances contains ingredients added directly to food that FDA has either approved as food additives or listed or affirmed as GRAS. Nevertheless, it contains only a partial list of all food ingredients that may in fact be lawfully added to food, because under federal law some ingredients may be added to food under a GRAS determination made independently from the FDA. The list contains many, but not all, of the substances subject to independent GRAS determinations. The list below is an alphabetical inventory representing only five of 196 fields in FDA/CFSAN's PAFA database. To obtain the entire database, including abstractions of over 7,000 toxicology studies performed on substances added to food as well as a search engine to locate desired information, order Food Additives: Toxicology, Regulation, and Properties, available in CD-ROM format from CRC Press.
    [Show full text]
  • Pyrimidinedione Derivative Compounds, Method of Producing
    Europa,schesP_ MM II M M MM II II II II III II I II J European Patent Office _ © Publication number: 0 369 627 B1 Office europeen* des.. brevets , © EUROPEAN PATENT SPECIFICATION © Date of publication of patent specification: 21.12.94 © Int. CI.5: C07D 239/54, C07D 401/12, A61K 31/505 © Application number: 89311135.1 @ Date of filing: 27.10.89 © Pyrlmldlnedlone derivative compounds, method of producing the same and antiarrythmic agents containing the same. © Priority: 29.10.88 JP 271992/88 © Proprietor: MITSUI TOATSU CHEMICALS, Inc. 06.12.88 JP 306840/88 2-5 Kasumigaseki 3-chome 06.12.88 JP 306841/88 Chiyoda-Ku 18.04.89 JP 96416/89 Tokyo 100 (JP) 18.04.89 JP 96417/89 18.04.89 JP 96418/89 @ Inventor: Katakami, Tsutomu 06.09.89 JP 229272/89 1651-17, Koshigoe 25.09.89 JP 246317/89 Kamakura-shi 25.09.89 JP 246318/89 Kanagawa-ken (JP) Inventor: Yokoyama, Tatsuro @ Date of publication of application: 3-5-10-404, Namiki 23.05.90 Bulletin 90/21 Kanazawa-ku Yokohama-shl © Publication of the grant of the patent: Kanagawa-ken (JP) 21.12.94 Bulletin 94/51 Inventor: Miyamoto, Mlchihiko 2882-3-31, lijimacho © Designated Contracting States: Sakae-ku AT BE CH DE ES FR GB IT LI NL SE Yokohama-shi Kanagawa-ken (JP) © References cited: Inventor: Mori, Haruki H-509, Nyuraifu DE-A- 2 819 629 Kanazawabunko 1200-6, Kamariyacho 00 CHEMICAL ABSTRACTS, vol. 112, 1990, page Kanazawa-ku IV 432, abstract no. 62669q, Columbus,Ohio, Yokohama-shi CM US; & JP-A-01 175 937 (MITSUI TOATSU Kanagawa-ken (JP) CO CHEMICALS, INC.) 12-07-1989 o> CO 00 Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted.
    [Show full text]