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Pharmacology Notebook a PDF (Searchable) The Shulgin Lab Books December 2016 Pharmacology Notes A (1985-1986) A Bit About This Document: While undertaking the work of investigating the chemistry and pharmacology of many varied psychoactive substances, Alexander “Sasha” Shulgin kept detailed notebooks. His documentation covered not only on his own personal research, but the research of friends and acquaintances. This book is the start of a new series representing a change of direction, stepping away from his personal work-ups, this book contains only the reports of others. It covers mostly 1985 through 1986. The Creation of This Document: The project to undertake the transcribing of Shulgin’s Lab Books was started in 2008 by a team of volunteers and staff at Erowid, along with members of Team Shulgin. Various books were transcribed without a clear idea of how to present the information as a final product; eventually this format was chosen and a volunteer began work assembling the document. Each page was painstakingly transcribed from scanned images. All the hand-drawn “dirty pictures” (molecule drawings) and graphs were edited from the original scans and combined with drawn-in marks, outlines, and arrows to form this searchable PDF. Most of the names in this document have been redacted and pseudonyms put in their place. Names are presented as much as possible as they were in the original book, for example “Robert Thompson” is also “Robert”, “R.Thompson”, and “RT”. Initials are frequently used, and no two people share names or initials so the reader can keep track of who’s who. (ATS is Sasha and AP is Ann) Words highlighted in yellow are words that the transcription team could not decipher. If you think you can help us decipher some of these words, please contact [email protected]; we would love your help. This document is intended to resemble the look and feel of the original lab book as much as possible; minor corrections and clarifications have been made to make things easier to read, and to better fit this format. Words created specifically by Shulgin remain as found, for example: “Tooth-rubby” to describe bruxism. Shulgin uses some shorthand throughout this book; the only shorthand we have made an effort to clarify is the use of the letter “c” with a dash above it (from the Latin word cum, meaning “with”), which had been replaced by “[with]”. Other common shorthand to note: ∴ is “therefore”, ≅ is “approx. equal to”, ≡ is “identical to”, and ≎ is “equivalent to”. Bold text represents typewritten documents that were pasted into the lab book by Shulgin, and bold italic text represents handwritten documents pasted into the book that are not in Shulgin’s handwriting. All other text is Alexander Shulgin’s. Credits: Erowid Project Lead: Shawn Corrado Transcription: Bananaskin, Brian Davis, GoronZero, Hand, Jessica, Zelig Kopel, Marv, Mia, Teis Image Editing/Redacting/PDF Assembly: Shawn Corrado Team Shulgin: Sasha & Ann, Paul Daley, Tania & Greg Manning Erowid: Earth, Fire, Spoon The original version of this document and supporting files can be found here: http://www.erowid.org/library/books_online/shulgin_labbooks/ For any questions or comments please contact [email protected] Projects like this one are made possible by your continued support, please visit Erowid.org/donations LAB BOOK DEVOTED TO THE REPORTS OF OTHERS. INDEXED IN #7 as A-[page] Fred Brandt on 2C-T-4 1 Ann Shulgin on 2C-N 3 Fred Brandt on 2C-B and 2C-T-2 4 Rick Strassman on 5-Meo-DMT 5 Neil Tusa on 2C-T-13 8 Unknown on MDMA and 2C-T-2 10 Celine on 2C-B 12 Fred Brandt on MDMA and 2C-T-2 13 Celine on MDMA 18 Celine on MDMA 20 Fred Brandt on MDMA 22 Fred Brandt on MDMA and MEM 24 Peggy Brandt on MDMA and MEM 25 Ann Shulgin on 2C-T-4 27 Fred Brandt on 2C-T-2 28 Ann Shulgin on 2C-P 30 Ann Shulgin on 2C-T-2 31 Fred Brandt on BOD 35 Neil Tusa on 2C-T-4 38 Fred Brandt on PEGASUS 42 Fred Brandt on 2C-T-2 43 Fred Brandt on 'Death Valley Compound' 45 Ann Shulgin on 2C-D 46 Fred Brandt on 'Death Valley Compound' 47 Fred Brandt on 2C-D-5ETO 49 Peggy Brandt on 2C-T-4 51 Neil Tusa on 2C-D 52 Fred Brandt on 2C-T-2 53 Peggy Brandt on 2C-T-2 55 Peggy Brandt on 2C-T-2 57 Peggy Brandt on 'Death Valley Compound' 58 Fred Brandt on BD 60 Peggy Brandt on BD 62 Fred Brandt on PEGASUS 64 Scott Nader on 5-Meo-MIPT 65 Scott Nader on MDMB 68 Scott Nader on 2C-T-2 71 Rick Strassman on 5-Meo-MIPT 73 Fred Brandt on PEGASUS 76 Fred Brandt on 2C-P 77 Peggy Brandt on 2C-P 79 Peggy Brandt on 2C-T-2 80 Fred Brandt on 2C-T-2 81 Unknown on 5-MEO-DMT and Harmaline (Strassman?) 83 Vera & Nolan on 2CB 86 Vera & Nolan on 2C-T-2 87 Fred Brandt on 2C-T-2 89 Ann Shulgin on 2C-T-8 91 Unknown on AL-LAD 92 Fred Brandt on 2C-T-2 94 Fred Brandt on 2C-T-2 95 Unknown on FLEA (Neil Tusa?) 96 Unknown on FLEA (Neil Tusa?) 97 Unknown on 2C-D (Neil Tusa?) 98 Unknown on 2C-T-8 (Neil Tusa?) 99 Clare Tusa on FLEA or MMH 101 Neil Tusa on FLEA? 103 Fred Brandt on 2C-T-13 and 2C-T-2 105 Unknown on 2C-T-4 107 Reynard Jacox on MDMA 109 Scott Nader on 2C-T-2 111 Ann Shulgin on DOC 113 Tina Gates on FLEA 115 Fred Brandt on PEGASUS 116 Fred Brandt on 'Death Valley Compound' 117 Peggy Brandt on PEGASUS 119 1 REPORT OF EXPERIMENT WITH 2-C-T-4 Date: June 5, 1985 Place: Brandt residence, Lone Pine Participants: Peggy and Fred 10:06 a.m. Peggy takes 8 m.g., Fred 9 m.g., of 2-C-T-4. Slow, gradual onset, about 20 minutes to first feel. Very smooth, gradual development. Beautiful to sit outdoors in shade, talking over many things seldom have time for. Marvelous ascent –- clean, gentle, smooth. Perception heightened, conversation easy. 11:30 a.m. Reluctant to go inside, but once I try it, am entranced. Find it easy to explore questions, find answers. Go inside the house and lie down, Peggy prefers outdoors. I begin to feel lonely. Examine why I came to Lone Pine, choose to spend many days at home alone. Main search is find self. As I look, I find intense loneliness, but after a while love for myself begins to grow; work at this until finally break free with tremendous appreciation of myself. Most fulfilling Experience. Peggy and I spend rest of the afternoon in living room, lying down and sometimes listening to music. Experience continues to grow in intensity for over 3 hours, stays at intense level for many hours after. Turns into the most complete, profound, and thorough exploration I have ever undergone. Remarkable material, allowing one to look anywhere, empowering the exploration of any chosen subject. Bodywise, clean and clear. Experience remains smooth and gentle. Even when exploring uncomfortable areas, overall feeling tone still good. Saw clearly into my own functioning, relationships, dynamics of other people I looked at, general philosophical truths. An important characteristic of this experience was the ease of letting go and flowing with the experience, partly due to the efficacy of this material and partly to my progress in learning. I often found best way to use the material was just let go and follow where it led, regardless of what resistances might build up (sometimes intense body contractions). In time this would usually result in a growing in euphoria, a feeling of clearing out of body residues, and often culminating in profound insight. As the day wore on, thinking continued to grow in clarity, visual perception was crystal clear, and it was a great joy to simply look over the scenery, enjoy the beauty, enjoy the companionship, and ponder whatever came to mind. The feeling of closeness and understanding with Peggy developed steadily during the day. Never before have we enjoyed so much just the two of us being together and relating. One of the things I worked on the most was the iggy feelings that would come over me from time to time. I never got a real answer to them, but found it best to simply ride them through, even when very uncomfortable. I sensed I might be able to change things by thinking differently, but this often felt like such an effort that it was foreign to my being and I simply rode it out. As the experience wore on, it was easier and easier to change my feelings by changing the focus of my thoughts. However, I never felt like pushing, as it seemed more honest to just go along with what was happening. In fact a major lesson of the day was honesty, to simply be what I am, even with my idiosyncrasies, and not be continually trying to change and be different. I achieved a great state of peace and contentment with myself and the way things are -- a wonderful natural feeling. 2 At the same time, dancing was very revealing. Midafternoon, though tired, I started to move to the High Energy Dance Music. I was soon caught up in it, and expressing myself deeply. I flowed easily with the music, but was amazed at the intensity of the feelings that came up.
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