FBLIM1 Polyclonal Antibody

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PRODUCT DATA SHEET Bioworld Technology,Inc. FBLIM1 polyclonal antibody Catalog: BS72779 Host: Rabbit Reactivity: Human,Rat BackGround: munogen and the purity is > 95% (by SDS-PAGE). This gene encodes a protein with an N-terminal fila- Applications: min-binding domain, a central proline-rich domain, and, WB 1:500 - 1:2000 multiple C-terminal LIM domains. This protein localizes Storage&Stability: at cell junctions and may link cell adhesion structures to Store at 4°C short term. Aliquot and store at -20°C long the actin cytoskeleton. This protein may be involved in term. Avoid freeze-thaw cycles. the assembly and stabilization of actin-filaments and Specificity: likely plays a role in modulating cell adhesion, cell mor- FBLIM1 polyclonal antibody detects endogenous levels phology and cell motility. This protein also localizes to of FBLIM1 protein. the nucleus and may affect cardiomyocyte differentiation DATA: after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Molecular Weight: 41kDa Western blot analysis of extracts of rat heart, using FBLIM1 antibody. Swiss-Prot: Note: Q8WUP2 For research use only, not for use in diagnostic procedure. Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific im- Bioworld Technology, Inc. Bioworld technology, co. Ltd. Add： 1660 South Highway 100, Suite 500 St. Louis Park, Add： No 9, weidi road Qixia District Nanjing, 210046, MN 55416,USA. P. R. China. Email: [email protected] Email: [email protected] Tel: 6123263284 Tel: 0086-025-68037686 Fax: 6122933841 Fax: 0086-025-68035151 .

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Supplementary Table 5A
CE2/+ f/f CA/+ CE2/+ f/f Supplementary Table 5A: Pathway enrichment analysis for differentially expressed genes between Nkx3.1 ; Pten ; Braf and Nkx3.1 ; Pten mouse prostate tumors Pathway Gene Number Enrichment Normalized p-value False Family-wise Rank Leading Edge Genes Set of genes Score enrichment Discovery Error Rate at Details in the score Rate p-value Max pathway q-value TPM2 ACTG2 MYL9 ACTA2 VCL DES MYLK ITGA1 Details TPM4 SORBS1 CALM2 ITGB5 PXN LMOD1 TNNC2 1 REACTOME_MUSCLE_CONTRACTION ... 30 0.78 2.58 0 0 0 2180 MYL1 MYH11 Details TPM2 ACTG2 MYL9 ACTA2 VCL MYLK ITGA1 2 REACTOME_SMOOTH_MUSCLE_CONTRACTION ... 20 0.81 2.39 0 0 0 1609 TPM4 SORBS1 CALM2 ITGB5 PXN LMOD1 MYH11 ITGA3 LAMB3 ITGB4 THBS1 LAMA3 CD44 ITGA6 ITGAV ITGB1 SPP1 LAMC2 ITGA1 SDC1 RELN LAMC1 FN1 ITGB5 THBS2 COL1A2 ITGA9 ITGB6 SDC2 HSPG2 TNC COL6A1 COL4A2 COL6A2 Details COL4A6 ITGA5 COL4A1 LAMA1SV2B COL5A1 3 KEGG_ECM_RECEPTOR_INTERACTION ... 59 0.63 2.32 0 0 0 3812 COL6A3 COL3A1 ITGA11 COL5A2 ITGA10 Details ACTIN1 FLNC FBLIM1 ITGB1 FLNA RSU1 FERMT2 4 REACTOME_CELLEXTRACELLULAR_MATRIX_INTERACTIONS ... 13 0.81 2.16 0 0 0.001 1193 PXN ILK ITGA3 ITGB4 THBS1 ITGA6 ITGAV ITGB1 SPP1 ITGA1 LAMC1 FN1 ITGB5 COL1A2 CDH1 BCRAR1 ITGA9 ITGB6 COL4A5 TNC COL4A2 ITGA5 COL4A1 Details LAMA1 PTPN1 FGG PECAM1 FGA FBN1 ITGA11 5 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS ... 62 0.57 2.09 0 0 0.002 3812 ITGA10 COL1A1 LAMA2 LAMB2 ITGA3 CCND1 LAMB3 ITGB4 THBS1 FLNB LAMA3 ACTN1 IGF1R CCND2 ITGA6 ITGAV FLNC MYL9 CAV1 ITGB1 VEGF1 PDGFRA SPP1 FLNA MAP2K1 PDGFC VCL PPP1CC MYLK LAMC2 CAPN2 CDC42 ITGA1 RELN LAMC1 AKT3 FN1 CAV2 PDGFRB ITGB5 PXN ILK PDGFB THBS2 DOCK1 COL1A2 FLT1 FIGF BCAR1 ITGA9 ITGB6 PAK3 TNC COL6A1 COL4A2 COL6A2 COL4A6 ITGA5 COL4A1 LAMA1 Details BCL2 COL5A1 PGF ZYX COL6A3 COL3A1 ITGA11 6 KEGG_FOCAL_ADHESION ..
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