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A213III- Ovary Cancer Tissues Specifications: • No. of Cases: 30

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A213III- Ovary cancer tissues (formalin fixed) For research use only Specifications: • No. of cases: 30 • Tissue type: Ovary cancer tissues • No. of spots: 2 spots from each cancer case (60 spots) 10 non-neoplastic spots (10 spots) •Total spots: 70 • Corresponding normal tissues with cancers: No • Diameter: 1. 0 mm Documents: • Product specification: layout, summary of tissue spots • H&E stained images • Detailed pathological information Layout: P-07-04-10T A213III- Ovary cancer tissues (formalin fixed) For research use only Summary of tissue spots P-07-04-11T A213III- Ovary cancer tissues (formalin fixed) For research use only Summary of tissue spots P-07-04-11T A213III- Ovary cancer tissues (formalin fixed) For research use only QC sheet_LOT#122121207131 Hematoxylin and Eosin staining A1 A2 A3 A4 A5 A6 A7 A8 A9 A10 B1 B2 B3 B4 B5 B6 B7 B8 B9 B10 C1 C2 C3 C4 P-07-04-12T A213III- Ovary cancer tissues (formalin fixed) For research use only QC sheet_LOT#122121207131 Hematoxylin and Eosin staining C5 C6 C7 C8 C9 C10 D1 D2 D3 D4 D5 D6 D7 D8 D9 D10 E1 E2 E3 E4 E5 E6 E7 E8 P-07-04-12T A213III- Ovary cancer tissues (formalin fixed) For research use only QC sheet_LOT#122121207131 Hematoxylin and Eosin staining E9 E10 F1 F2 F3 F4 F5 F6 F7 F8 F9 F10 G1 G2 G3 G4 G5 G6 G7 G8 G9 G10 P-07-04-12T A213(III): Ovary cancer tissues NoCoordinate Sex Age Key Word Histological Diagnosis Uterus with both adnexae, radical abdominal hysterectomy with bilateral salpingooophorectomy: Cervix: Chronic nonspecific inflammation. Endometrium: Atrophy. Myometrium : Adenomyosis. Ovaries, bilateral: Serous papillary cystadenocarcinoma, moderately differentiated, bilateral, with extension beyond ovarian capsule to the pelvic peritoneum and cul de sac. Serous papillary Fallopian tubes, bilateral: Free of tumor. 1 A 1,2 f 60 cystadenocarcinoma Parametrium, right: Metastatic serous adenocarcinoma. Parametrium, left : Free of tumor. Vaginal cuff: Metastatic adenocarcinoma involving cul de sac. Peritoneum, biopsy: Presence of metastatic adenocarcinoma. Omentum, omentectomy: Free of tumor. Lymph nodes, right pelvic(0/1) and left pelvic(0/1): Free of tumor in all 2 lymph nodes(0/2). Ovary and fallopian tube, left, left salpingooophorectomy: Serous adenocarcinoma, poorly differentiated, of tubal serous 2 A 3,4 f 53 origin, adenocarcinoma with extension to the ovarian surface(pT2A) . Ovary and fallopian tube, right, right salpingooophorectomy: Serous papillary Ovary: Serous papillary cystadenocarcinoma, moderately differentiated, with extraovarian spread, bilateral 3 A 5,6 f 41 cystadenocarcinoma Fallopian tube: Intraluminal spread of ovarian serous adenocarcinoma. Uterus with right adnexa, total abdominal hysterectomy with right salpingooophorectomy: Cervix: 1. Chronic nonspecific inflammation with squamous metaplasia. 2. Metastatic ovrian adenocarcinoma involving paracervical and deep cervical stroma. Endometrium: Proliferative phase. Myometrium: Metastatic ovarian adenocarcinoma involving serosa and myometrium. Serous papillary 4 A 7,8 f 43 Ovary, right: Serous papillary adenocarcinoma, poorly differentiated, bilateral, with extraovarian spread. adenocarcinoma Fallopian tube, right: Metastatic adencoarcinoma. Parametriums, both: Metastatic adenocarcinoma. Lymph nodes, right pelvic(2/12), left pelvic(2/8) and paraaortic(2/6): Metastasis in 6 out of 26 nodes. Omentum, omentectomy: Metastatic adenocarcinoma. P-07-04-13T A213(III): Ovary cancer tissues NoCoordinate Sex Age Key Word Histological Diagnosis Ovary and fallopian tube, right, right salpingooophorectomy: Ovary: Malignant mixed mullerian tumor composed of mixed serous and endometrioid 5 A 9,10 f 56 adenocarcinoma adenocarcinoma and heterologuous rhabdomyosarcomatous component, confined within ovarian capsule. Fallopian tube: No pathological diagnosis. Desmin: positive, Actin: negative. Uterus with both adnexae, total abdominal hysterectomy with bilateral salpingooophorectomy: Cervix: Chronic nonspecific inflammation with squamous metaplasia. Endometrium: Atrophy. Myometrium: Serosal and deep myometrial invasion by metastatic ovarian serous adenocarcinoma. Ovaries, bilateral: Serous surface papillary adenocarcinoma, bilateral, FIGO grade II, Silverberg grade III Serous surface (8/9 scores), with spread along the peritoneal surface and extensive lymphovascular invasion. 6 B 1,2 f 63 papillary Fallopian tubes, bilateral: Free of tumor. adenocarcinoma Parametrium, right: Free of tumor. Parametrium, left: Extension of tumor with lymphatic permeation. Vaginal cuff: Free of tumor. Lyypmph node, dissection: Metastatic serous adenocarcinoma in 13 out of 33 l ypymph nodes , in detail, right pelvic(1/8), left pelvic(0/4), paraaortic(12/21). Uterus with both adnexae, total abdominal hysterectomy with bilateral salpingooophorectomy: Cervix: Low grade squamous intraepithelial lesion (CIN grade I). Endometrium: Proliferative phase. Myometrium: 1. Metastatic ovarian serous adenocarcinoma involving the serosa. 2. Adenomyosis. Ovary, left: Serous papillary cystadenocarcinoma, grade II, bilateral with capsular invasion and extraovarian spread. Fallopian tube, right: Metastatic serous adenocarcinoma of the ovary, involving paratubal ligament Serous papillary and serosal surface. 7 B 3,4 f 49 cystadenocarcinoma Fallopian tube, left: Intraluminal spread of ovarian carcinoma. Parametrium, both: Metastatic adenocarcinoma. Vaginal cuff: Free of tumor. Lymph node, dissection: Free of tumor in all 13 lymph nodes (0/13), in detail, right pelvic(0/4), left pelvic(0/4), paraaortic(0/5). Omentum, omentectomy: Metastatic adenocarcinoma. P-07-04-13T A213(III): Ovary cancer tissues NoCoordinate Sex Age Key Word Histological Diagnosis Uterus with both adnexae, total abdominal hysterectomy with bilateral salpingooophorectomy: Cervix: Erosion with acute and chronic nonspecific inflammation. Endometrium: Atrophy. Serous surface Myometrium : 1. Adenomyosis. 8 B 5,6 f 76 papillary 2. Metastatic serous adenocarcinoma involving serosa. adenocarcinoma Ovaries, bilateral: Serous surface papillary adenocarcinoma, moderately differentiated, with extraovarian spread. Fallopian tube, right: Metastatic adenocarcinoma involving fimbria. Fallopian tube, left: Free of tumor. Ovary and fallopian tube, left, left salpingooophorectomy: Serous papillary 9 B 7,8 f 49 Ovary: Serous papillary cystadenoma. cystadenoma. Fallopian tube: No pathological diagnosis. Uterus with both adnexae, total abdominal hysterectomy with bilateral salpingooophorectomy: Cervix: Chronic nonspecific inflammation with squamous metaplasia and atrophy. Endometrium: Cystic atrophy. Serous papillary 10 B 9,10 f 77 MtiNthlildiiMyometrium: No pathological diagnosis. cystadenocarcinoma Ovaries, right: Endosalpingiosis. left: Serous papillary cystadenocarcinoma, poorly differentiated, confined to the ovarian parenchyme. Fallopian tubes, bilateral: Free of tumor. Uterus including both adnexae, total abdominal hysterectomy with bilateral salpingooophorectomy: Cervix: Atrophy. Serous papillary Endometrium: Metastatic ovarian serous adenocarcinoma along endometrial lymphatics. 11 C 1,2 f 74 adenocarcinoma Myometrium: Metastatic serous adenocarcinoma involving serosa Ovaries, bilateral: Serous papillary adenocarcinoma, moderately differentiated, bilateral with extension beyond ovarian capsule and spread to peritoneal surface. Ovary, left, oophorectomy: Serous papillary adenocarcinoma, grade III, with extraovarian spread. Peritoneum: Metastatic serous adenocarcinoma. Serous papillary 12 C 3,4 f 48 Appendix: Acute serositis with congestion. adenocarcinoma Omentum: Free of tumor. Lymph node, dissection: Free of tumor in all 15 lymph nodes, in detail, right pelvic(0/5), left pelvic(0/5), paraaortic(0/5). P-07-04-13T A213(III): Ovary cancer tissues NoCoordinate Sex Age Key Word Histological Diagnosis Uterus with right adnexae, total abdominal hysterectomy with right salpingooophorectomy: Cervix: Chronic nonspecific inflammation Endometrium: 1. Polyp. 2. Atrophy. Serous papillary 13 C 5,6 f 53 Myometrium: 1. Metastatic serous adenocarcinoma involving the serosa. cystadenocarcinoma 2. Adenomyosis. Ovary, right: Serous papillary cystadenocarcinoma, grade III, with extensive extraovarian spread. Fallopian tube, right: Paratubal spread of adenocarcinoma. Parametrial margins, bilateral: Free of tumor. Ovary and fallopian tube, right, right salpingooophorectomy: Serous papillary 14 C 7,8 f 52 Ovary: Serous papillary cystadenocarcinoma, grade III, with extraovarian spread. cystadenocarcinoma Fallopian tube: Paratubal extension of the tumor. Uterus with both adnexae, total abdominal hysterectomy with bilateral salpingooophorectomy: Cervix: 1. Erosion. 2. Endocervical polyp. Endometrium: Atrophy. Myometrium: 1. Adenomyosis. Serous papillary 15 C 9,10 f 74 2. Metastatic ovarian adenocarcinoma involving serosa. adenocarcinoma Ovaries, bilateral: Serous papillary adenocarcinoma, high grade, with marked lymphovascular permeation, with extension beyond ovarian capsule. Fallopian tube, right: Metastatic adenocarcinoma. Fallopian tube, left: Free of tumor. Parametriums, bilateral: Free of tumor. serous Appendix, appendectomy: 16 D 1,2 f 75 adenocarcinoma Metastatic ovarian serous adenocarcinoma involving periappendiceal flat tissue. P-07-04-13T A213(III): Ovary cancer tissues NoCoordinate Sex Age Key Word Histological Diagnosis Uterus with right adnexa, total abdominal hysterectomy with right salpingooophorectomy: Cervix: Chronic nonspecific inflammation. Endometrium: Cystic atrophy. Myometrium: 1. Metastatic serous adenocarcinoma
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  • Treatment Strategy for Patients with Cystic Lesions Mimicking a Liver Tumor a Recent 10-Year Surgical Experience in Japan

    Treatment Strategy for Patients with Cystic Lesions Mimicking a Liver Tumor a Recent 10-Year Surgical Experience in Japan

    ORIGINAL ARTICLE Treatment Strategy for Patients With Cystic Lesions Mimicking a Liver Tumor A Recent 10-Year Surgical Experience in Japan Mitsuo Shimada, MD, PhD; Kenji Takenaka, MD, PhD; Tomonobu Gion, MD; Yuh Fujiwara, MD; Kenichi Taguchi, MD; Kiyoshi Kajiyama, MD; Ken Shirabe, MD; Keizo Sugimachi, MD, PhD Objective: To clarify some of the difficulties in deter- rhage in 7 patients, localized cystic dilation of the bile duct mining the appropriate surgical indications for cystic le- due to hepatolithiasis in 1, cystadenoma in 1, and mucin- sions mimicking a neoplasm in the liver. producing cholangiocarcinoma in 1. In only one case was postoperative diagnosis identical to the preoperative diag- Design: A retrospective review of hepatic resections for nosis. In one case, an intraoperative pathological exami- cystic lesions mimicking a neoplasm in the liver be- nation showed the tumor to be a mucin-producing cho- tween August 1, 1986, and July 31, 1996. langiocarcinoma instead of a cystadenocarcinoma. A tumor- marker analysis of the fluid in the cystic lesions also did Setting: A university hospital with a long history of he- not contribute to a definite diagnosis. Furthermore, cyto- patic resection for cystic lesions mimicking a neoplasm logical examination of the fluid could not completely ex- in the liver. clude malignancy. Neither mortality nor morbidity oc- curred in any of the patients, and their mean length of Patients: Ten patients with such cystic lesions in the hospitalization after hepatectomy was only 13.7 days. liver, who underwent a hepatectomy during a recent 10- year period, were included in this study. Conclusions: The accurate diagnosis of cystic lesions mimicking a tumor remains problematic; however, the Main Outcome Measures: Detailed clinicopatho- results of hepatectomy for such cases are normally sat- logic data were analyzed, and comparisons were made isfactory.