FY 2020” (Hereinafter Unit Long Term Achieve to Performance to Drive Plan”) Designed RSU As “The Key Strategic Plan

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FY 2020” (Hereinafter Unit Long Term Achieve to Performance to Drive Plan”) Designed RSU As “The Key Strategic Plan Biocon SEZ, Biocon Park, Plot No. 2 & 3, Bommasandra Industrial Area, IV Phase, Jigani Link Road, Bengaluru 560 099, Karnataka, India T +91 80 6891 8000 CIN: L85110KA1993PLC01493 Ref: Syn/CS/SE/AGM 2020/2020-21/31 www.syngeneintl.com June 29, 2020 To, To, The Manager Listing The Manager Listing BSE Limited National Stock Exchange of India Limited Corporate Relationship Department Corporate Communication Department Dalal Street, Mumbai – 400 001 Bandra (EAST), Mumbai – 400 051 Scrip Code: 539268 Scrip Symbol: SYNGENE Dear Sir/Madam, Subject: Notice of 27th Annual General Meeting (“AGM”) and Annual Report for FY 2019-20 We wish to inform you that the 27th AGM of the Company will be held on Wednesday, July 22, 2020 at 4:00 P.M. IST through Video Conferencing (“VC”) / Other Audio-Visual Means (“OAVM”). In this regard and in compliance of Regulation 34 of SEBI (Listing Obligation and Disclosure Requirements) Regulations, 2015, please find attached the Notice of the 27th AGM of the Company and the Annual Report for FY20, which is being circulated to the shareholders through electronic mode. The Notice of the 27th AGM and the Annual Report for FY 2019-20 are also available on the Company’s website at https://www.syngeneintl.com/investor-relations/latest-report-filings. Further, pursuant to Regulation 42 of SEBI (Listing Obligation and Disclosure Requirements) Regulations, 2015, Company has fixed Wednesday, July 15, 2020, as the cut-off date for determining the list of members who are eligible to participate and vote at the AGM. Information at a glance: - Particulars Details Date and time of AGM Wednesday, July 22, 2020 at 4:00 P.M.(IST) Mode Video Conferencing / Other Audio-Visual Means Participation through video- conferencing https://emeetings.kfintech.com Cut-off date for e-voting July 15, 2020 E-voting start date and time Friday, July 17, 2020 (9:00 hours)(IST) E-voting end date and time Tuesday, July 21, 2020 (17:00 hours)(IST) E-voting website https://evoting.karvy.com/ Request you to kindly take this intimation on record. Yours faithfully, For SYNGENE INTERNATIONAL LIMITED ____________ Priyadarshini Mahapatra Company Secretary and Compliance Officer Enclosed: Notice of 27th AGM and Annual Report for FY 2019-20 Annual Report 2019-20 Clinical & Commercial Drug Substance & Supplies Product Pharmaceuticals Agriculture Large MoleculesBiotechnology Small Molecules Oligonucleotide Synthesis Research Discovery Biology Informatics & Chemistry AntibodyConjugates Drug Animal Health Nutrition Cosmetics Specialty Molecules Clinical Studies Integrated Innovation Syngene at a glance >360 8 Rs. 20,935 Mn active clients collaborations with the revenue for FY20 top ten pharmaceutical companies >4,200 90% Rs. 3,662 Mn scientists employees in the PAT for FY20 25-40 year age bracket 1.9 Mn sq. ft. 400+ Rs. 31,541 Mn of R&D and manufacturing Patents held capex investment infrastructure with clients All figures are as on March 31, 2020, unless otherwise specified At the core of our operations is the quest IN THIS YEAR’S REPORT to apply cutting-edge scientific research to Business Review the many complex challenges of industry, Our Impact Manifesto 02 and human and animal health. Over Integrated Innovation 04 the last 25 years, like the honeycomb About the Company 06 structure, we have incrementally expanded Chairperson’s Message 12 our scientific expertise enabling us to Managing Director and 16 CEO’s Message offer integrated services across the Financial Review 20 discovery, development and manufacturing Our Journey 24 spectrum. We believe it is this integrated Market Overview 26 approach that drives innovation and Value Creation Model 28 helps us develop value-added solutions to Strategic Priorities 30 complex scientific challenges. Today, we Business Review 32 partner with a global clientele covering a Quality Management 44 Driving Operational Excellence 46 range of industries from pharmaceuticals Integration in Enabling Functions 48 to biotechnology, agriculture to animal Our Employees 50 health, cosmetics to nutrition and others. Integrating Sustainability 52 As the world extends the frontiers of Integrating with our Communities 54 science, we are committed to adding new Dealing with the pandemic 56 layers of expertise that will further drive Board of Directors 58 integrated innovation. Executive Committee 60 Corporate Information 62 Statutory Reports Board’s Report 63 Corporate Governance Report 100 Business Responsibility Report 127 Management Discussion and Analysis 137 Financial Statements Standalone Financial Statements 150 Consolidated Financial Statements 208 AGM Notice 266 The cover page represents a hexagonal honeycomb structure which symbolises integration, innovation, sustainability and To view this report online, flexibility; attributes that define Syngene. please visit: www.syngeneintl.com Our Impact Manifesto 02 I Syngene International Annual Report 2019-20 Business Review At Syngene, we aim to make a Our Aims contribution to the evolution of Capability Additions • Continuously adopt new technologies to improve scientific research using our skills, efficiency while lowering the overall cost of technology and experience to discovery and development find solutions to the world’s most • Increase the integration between services in complex challenges. Discovery to reduce project timelines and deepen our involvement in client projects By providing access to the latest • Continue development of our Biologics technology and highly trained capabilities to keep pace with the evolving science and technology scientists, underpinned by our • Build our expertise in advanced technologies values of integrity, excellence and such as sophisticated immuno-oncology professionalism, our aim is to be a assays and CAR-T design for researching next- trusted partner for clients seeking to generation therapies explore the boundaries of science at • Extend the process knowledge gained in the development stages of R&D to advise clients affordable cost. about potential manufacturing requirements over the long term Our services span the value chain from discovery to the clinic. Beyond Capacity Expansion • Continuous investment in technology and the science, our strengths lie in our infrastructure to deliver leading edge science and relentless pursuit of operational meet the demands of blue chip clients excellence; flexible business models; • Boost our commercial-scale manufacturing investment in data integrity; and capacity for small molecules by completing the construction and commissioning of our API passion for quality. manufacturing plant at Mangaluru We are proud to have partnerships • Invest in expanding our biologics manufacturing capacity that are deeply founded and nurtured over the years, delivering Partnering for Success • As a trusted partner, accelerate innovation and a level of commitment and deliver integrated solutions with great efficiency understanding that drives innovation at world-class levels of quality and service and scientific advances, thus linking • Boosting the R&D productivity of our clients our success to that of our clients and through scientific excellence and an integrated end-to-end research, development and the people and patients they serve. manufacturing approach Syngene International Annual Report 2019-20 I 03 Integrated Innovation At Syngene, our core capabilities are highly effective We harness the power of problem-solving and scientific innovation, allied to a clear science and technology to commitment to safety, quality and operating excellence. We deliver integrated innovation take an integrated approach with pace and efficiency across to the disciplines of discovery, development and manufacturing a diverse range of scientific to ensure project delivery on time, to quality, every time domains. - all with a single-minded commitment to turning clients’ ideas into meaningful innovation. Jonathan Hunt Managing Director & Chief Executive Officer 04 I Syngene International Annual Report 2019-20 Business Review Through seamless and customised services in discovery, is growing due to its inherent advantages: a single trusted development and manufacturing of novel molecules - both supplier to manage all process steps; a flexible resource to large and small, we offer clients an end-to-end solution accommodate rapid scale-up or wind-down as needed; tailored to meet their R&D requirements. In addition to strong end-to-end project management and tighter project delivery scientific expertise and world-class infrastructure, other factors timelines; and affordable costs. This approach allows some such as an experienced leadership team, track record of clients to transform the fixed cost of R&D operations into a quality and compliance, focus on safety, robust supply chain variable cost and for others, often smaller companies and and strong talent pool help create a vibrant ecosystem that start-ups, it provides a formula that removes the burden of fosters integrated innovation. Our approach enables us to substantial capital investment. forge client relationships that move beyond the traditional service outsourcing model into true end-to-end collaborations, At Syngene, we know that trust is a critical success factor expediting innovation with efficiency across the continuum. in every relationship. Guided by our values of Excellence, Integrity and Professionalism, we recognise that trust is built As companies – from small start-ups to large global incrementally project-by-project and we pride ourselves on the organisations – increasingly
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