Barts and the London School of Medicine and Dentistry an Overview Pub4494 SMD Overview V8.Qxd 28/5/09 08:30 Page 2 Pub4494 SMD Overview V8.Qxd 28/5/09 08:30 Page 3

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Barts and the London School of Medicine and Dentistry an Overview Pub4494 SMD Overview V8.Qxd 28/5/09 08:30 Page 2 Pub4494 SMD Overview V8.Qxd 28/5/09 08:30 Page 3 Pub4494 SMD Overview v8.qxd 28/5/09 08:30 Page 1 Barts and The London School of Medicine and Dentistry An Overview Pub4494 SMD Overview v8.qxd 28/5/09 08:30 Page 2 Pub4494 SMD Overview v8.qxd 28/5/09 08:30 Page 3 Introduction www.smd.qmul.ac.uk Barts and The London School of Medicine and Dentistry is one of the UK and London’s leading centres of excellence in medical and dental research and education. The results of the 2008 Research Assessment Exercise, conducted by the UK higher education funding councils, placed Barts and The London as 4th in the UK, and 1st in London, for the quality of research; the Dental School was ranked 1st equal in the UK. The School’s parent institution, Queen The School is currently organised into • skin disease Mary, University of London (p12-13), six institutes: • genomics is similarly ranked among the top • Blizard Institute of Cell • neuroscience research focused universities in the and Molecular Science UK: 11th overall in the 2008 Research • gastroenterology Assessment Exercise. • Institute of Cancer • epidemiology • William Harvey Research Institute Barts and The London School of • public health and primary care Medicine and Dentistry serves a • Wolfson Institute of Preventive population of unrivalled diversity in east Medicine The School is nationally and London and the wider Thames Gateway, • Institute of Health Sciences Education internationally recognised for research in these areas. Its fundamental mission, with a high prevalence of diabetes, • Institute of Dentistry hypertension, heart disease, with its partner NHS Trusts, and other tuberculosis and other chronic lung Through partnership with our linked linked organisations, such as CR-UK, diseases, HIV, oral disease, and cancer. trusts, notably Barts and The London is to ensure that that the best possible To follow the London Underground from NHS Trust, and our associated clinical service is underpinned by the Westminster to Canning Town, in health University Hospital Trusts – Homerton, very latest developments in scientific terms, is to see a reduction in life Newham, Whipps Cross and Queen’s and clinical teaching, training and expectancy of one year for each station – (Romford) – the School’s research and research. an astonishing and scandalous six years teaching is informed by an exceptionally We pride ourselves on being a School in all. wide ranging and stimulating clinical that is committed to: Barts and The London is committed environment. to changing this situation by giving • achievement of international academic leadership to North East At the heart of the School’s mission lies excellence in our chosen areas London health, by training outstanding world class research, the result of a of research and education clinicians, and by producing excellent focused programme of recruitment • and through this, in collaboration with medical and dental research, with a of leading research groups from the our NHS partners, contributing to our strong focus on translational research. UK and abroad, and a £100 million uniquely complex and diverse social investment in state-of-the-art facilities. and clinical environment in east The School has almost 1,000 members Research is focused on: London and the Thames Gateway, of staff, consisting of over 650 • translation of basic research into man which offers research, teaching academics and around 350 support • cancer and clinical opportunities unrivalled staff. The School’s total annual turnover in the UK. is approximately £86 million of which • cardiovascular over £40 million is competitively • dentistry awarded external research income • inflammation additional to that received from HEFCE, placing Barts and The London in the top • endocrinology/metabolism tier of research active medical and • immunology and infectious diseases dental schools. Barts and The London School of Medicine and Dentistry 3 Pub4494 SMD Overview v8.qxd 28/5/09 08:30 Page 4 Our Research Excellence www.smd.qmul.ac.uk Over the past five years Barts The School’s translational research • The Wolfson Institute of Preventive strength has been recognised by, amongst Medicine, returned in Epidemiology and The London School of others, the award of a NIHR Biomedical and Public Health, was 2nd out of 21 Medicine and Dentistry has Research Unit in Cardiovascular Disease, in terms of 3* and 4* outputs, and 3rd been transformed into one of with a £5.375 million grant awarded in overall, ahead of Oxford, University 2008 to Barts and The London School of College London and Bristol. the top research institutions Medicine and Dentistry, and Barts and • In Health Services Research, we were The London NHS Trust. in the UK. ranked 4th overall out of 28, ahead of Oxford, University College London and Highlights include characterising In addition to our own National Institute Kings College London. susceptibility genes for complex diseases for Health Research Biomedical such as hypertension, diabetes and Research Unit, Barts and The London • The William Harvey Research Institute, coeliac disease; identifying the genes is a strategic partner in the NIHR returned in Preclinical and Human responsible for Harlequin Ichthyosis; Biomedical Research Centre based at Biological Sciences, was ranked 3rd showing that stem cells can regrow liver, Guy's and St Thomas' NHS Trust and in terms of 3* and 4* outputs, and 4th pancreas and intestine; the production of Kings College London. overall out of 13, ahead of Kings College the Down’s syndrome mouse; showing London, Bristol and Nottingham. that breast cancer screening reduces More than 25 world-class researchers mortality; producing the evidence that folic have been appointed at Professorial In addition to new senior staff, Barts acid should be added to bread in the UK, level since 2005, along with 50 new and The London is placing particular as happens in 31 other countries; and group leaders. emphasis on recruiting young researchers showing that vitamin D boosts immunity and supporting them to become stars of The 2008 Research Assessment to tuberculosis. the future. Exercise results showed Barts and Barts and The London School of Medicine The London School of Medicine and The School has a fully-integrated Joint and Dentistry has shown the largest Dentistry to be in the top four medical Research Office with Barts and The increase in research funding in the last schools in the UK, top in London and London NHS Trust which takes care of five years in the UK. The School has the the Dental School first equal. grant administration and, increasingly, is highest amount of blue-chip charitable providing academics with assistance in According to ranking published in the income in the UK, and our research spend the more complex types of proposals, Times Higher Education, Barts and The in 2006-7 placed us 11th in the Russell such as EU FP7. London scored consistently in the top five: Group of medical schools. Our 2007-8 Our Principal Investigators have protected spend of £41.5 million represents a 20 per • Dentistry was ranked 1st equal with research time in order to maximise their cent year-on-year increase, the highest in Manchester based on 3* and 4* productivity and are co-located into the UK, and moves us to 7th overall. Our outputs, and 2nd overall out of 14 research centres and environments of current portfolio of 1001 awards totals UK dental schools. critical mass underpinned by state-of-the- £125 million, including seven programme • In Cancer, we were ranked 3rd out of art core facilities in: Genomics; Functional grants from the MRC, seven programme 14 submissions in terms of 3* and 4* Genomics; Proteomics: Imaging, grants from Wellcome Trust, and 12 outputs and joint 5th in the UK overall, Transgenic and Knockout mouse unit; programme grants from Cancer Research ahead of Oxford, Imperial, Kings College and Structural Biology. A core Genomics UK. Among our senior investigators, 90 London and University College London. and Proteomics Centre has been funded per cent have at least one paper with by the Barts and The London Charitable greater than 100 citations and 14 of our • The Blizard Institute of Cell and Foundation (£3.1 million including senior researchers have, in total, an Molecular Science, returned in Hospital refurbishment). This Centre provides astonishing 309 papers with greater than Subjects, was ranked joint 1st with state-of-the-art facilities to support the 100 citations and individual “H factors” Cambridge and Edinburgh in terms of 3* School’s genomic and proteomics between 50 and 81. and 4* outputs and was joint 7th overall out of 28, ahead of Manchester, research programmes and associated Newcastle and Southampton. bioinformatics. 4 Barts and The London School of Medicine and Dentistry Pub4494 SMD Overview v8.qxd 28/5/09 08:31 Page 5 Selected Professorial Appointments made in the past five years: Malcolm Alison Professor of Stem Cell Biology Qasim Aziz Professor of Neurogastroenterology David Baker Professor of Neuroimmunology David Beach Professor of Cell Biology Inderjeet Dokal Professor of Haematology Marco Falasca Professor of Signal Transduction Gavin Giovannoni Professor of Neurology John Gribben Professor of Experimental Cancer Medicine Jonathan Grigg Professor of Paediatric Respiratory and Environmental Medicine Ian Hart Professor of Oncology David van Heel Professor of Gastrointestinal Genetics Louise Jones Professor of Breast Pathology Ajay Kakkar Professor of Surgical Sciences Professor of Cell Signalling, Bart Vanhaesebroeck Ania Korszun Professor of Psychiatry Nick Lemoine Professor
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