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Subhabrata Sen Ph.D. Vijayawada Subhabrata Sen Ph.D. Vijayawada, AP, India Contact: 0091 9810250221; Email: [email protected] Education Doctorate in Organic Chemistry University of Missouri-Columbia, USA Advisor: Dr. Shon R Pulley Mentor Experience 1. Completed PhD: Advisor: 3; Co-Advisor: 4 2. Ongoing PhD: Advisor: 4; Co-Advisor: 1 Research Experience 1. Postdoctoral Research Associate, 2001-2002: Department of Chemistry, Colorado State University, Fort Collins, CO, USA Advisor: Professor Albert I. Meyers 2. PhD, 1997-2001: Department of Chemistry, University of Missouri-Columbia, Columbia, MO, USA Advisor: Dr. Shon R. Pulley Employment History a. Professor, 08/2018-Present: Department of Chemistry, SRM University, AP b. Associate Professor and Head, 07/2016-07/2018: Department of Chemistry, Shiv Nadar University c. Associate Professor, 02/2013 – 06/2016: Shiv Nadar University d. Associate Director, 03/2010 – 12/2012: GVKBioscience located in Hyderabad, AP, India, e. Principal Scientist, 02/2009 – 02/2010: Jubilant Chemsys located in Noida, UP, India f. Senior Manager, 02/2008 – 01/2009: Pfizer VMPS, Mumbai, India. g. Senior Scientist, 03/2006 – 01/2008: BASF-India, Mumbai India h. Scientific manager, 04/2004 – 02/2006: Syngene International Private Limited, Bangalore, India. i. Scientist-1, 09/2002 – 03/2006: Chemocentryx Inc., Mountain View, California. Teaching Experience 1. Teaching Assistant (general chemistry course), University of Missouri, Columbia, MO, USA: Fall 1997-Spring 1998 2. Instructor and course coordinator (Shiv Nadar University): a. CHY 101 (General Chemistry for 1st year under graduate students): Monsoon 2013/Spring 2014/Monsoon 2014/Monsoon 2015/Spring 2016 b. CCC-CHY 401 (Small molecules and natural remedies for all under graduates all stream): Spring 2013 c. UWE-CHY 120 (Molecules and medicine for all undergraduates): Spring 2014/Spring 2015/Spring 2016 d. CHY 502 (Advanced Synthetic Organic Chemistry for PhD students): Spring 2014/ Monsoon 2014/Monsoon 2015 e. CHY 213 (Chemical Analysis lab for Chemistry Undergraduates): Spring 2015/Spring 2016 Awards and Fellowships 1. 2003: “Make it Happen” Award: Chemcentryx Inc., Mt. View, California, USA 2. Department of Science and Technology Travel Grant-2015 3. 2016: Seibold-Collegium Fellowship, Seibold Collegium Institute of Advances Studies, Julius-Maxmillians-Universität Würzburg, Würzburg, Germany Presentations 1. NTU-IISER-Bhopal Chemistry Workshop, 4th-6th January, 2018, IISER-Bhopal, Madhya Pradesh, India 2. Green Chemistry Conference, 8th-10th December, 2017, University of Auckland, Auckland, New Zealand 3. Conference on Frontiers in Organic Synthesis, 22nd-24th December, 2017, IIT-Roorkee, Uttarakhand, India 4. Novel multicomponent reactions in the synthesis of bioactive heterocycles. Invited Presentation in Sixth European Workshop in Drug Synthesis, 15th-19th May, 2016, Certosa di Pontignano, Siena, Italy. 5. Invited Presentation in 4th International Conference on Asian Network for Natural and Unnatural Materials, 8th-11th June, 2016, National University of Singapore, Singapore. Intuitive scaffold hopping strategy towards substituted furopyridinediones as novel inhibitors of α-glucosidase 6. Oral Presentation in International Conference on Pharmaceutical Bioinformatics, 2016, Pattaya, Thailand, 25th -27th January, 2016. Multicomponent reactions in the synthesis of biologically interesting heterocycles. 7. Invited lecture in Faculty of Medicinal Technology, Mahidol University, Nakhon Pathom, Thailand, 29th January, 2016. Diverse synthesis of natural product inspired fused and spiro scaffolds via ring distortion and construction strategy 8. Oral Presentation in MedChem 2015, SelectBio conference, Hyderabad, Telengana, 10th - 11th September, 2015. 9. Oral Presentation in Bioheterocycles 2015, Metz, France, 8th -11th June, 2015 Library design: phenotypic screening and target based approaches 10. Invited lecture in Asian Network for Natural and Unnatural Materials in Department of Chemistry, University of Punjab, Chandigarh, 28th February-2nd March, 2015. Natural product inspired chiral hybrid systems via biology driven diversity oriented synthesis (BDDOS) 11. Invited lecture in Department of Physical Sciences and Mathematics in Nanyang Technical University, Singapore, October 27th, 2014. Synthesis of novel and privileged scaffolds via diversity-oriented synthesis followed by phenotypic screening against cancer cell lines. 12. Invited Lecture on Medchem 2013, IIT-Chennai, Chennai, Tamil Nadu, India, October 25th-26th, 2013. Michael reaction of oxazoldiinones with Nitrostyrene:Efficient Accesses to Optically Active Quinolizidinones, Piperidinones and Pyrrolidinones Evolution from auxiliary to catalytic asymmetric synthesis. 13. Invited Lecture on 2nd World Congress of Catalytic Asymmetric Synthesis, Beijing, China, May 12th-14th, 2012. Natural Product Inspired Spirocyclic and Fused systems from chiral Bicyclic Lactams. 14. Invited Lecture on Practical Applications of Modern Tools in Organic Synthesis and Purifications II, Pune, Maharashtra, India, April 2nd –April 4th, 2012 Publications and Patents 55 Tania Luthra, § Akshay Kumar Nayak, § Sarpita Bose, Saikat Chakrabarti, Ashish Gupta * and Subhabrata Sen*, Indole based antimalarial compounds targeting the melatonin pathway: Their design, synthesis and biological evaluation, Eu. J. Med. Chem. 2019, Just accepted. 54 Deepika Chauhan§, Santanu Hati§, Richa Priyadarshini*, Subhabrata Sen*, Transcriptome analysis predicts mode of action of benzimidazole molecules 1 against Staphylococcus aureus UAMS-1, Drug Dev. Res. DOI: 10.1002/DDR.21523 53 Pratip K Dutta, Mahesh Kumar Ravva, Subhabrata Sen*, Cobalt catalysed, hydroxyl assisted C-H bond functionalization: Access to diversely substituted polycyclic pyrans, J. Org. Chem. 2019, doi: 10.1021/acs.joc.8b02446 52 Dandugudumula Ramu, Ravi Jain, Ravi Ranjan Kumar, Veena Sharma, Swati Garg, R Ayana, Tania Luthra, Preeti Yadav, Soumya Pati, Subhabrata Sen, and Shailja Singh*, Design and synthesis of imidazolidinone derivatives as potent anti- leishmanial agents by bioisosterism, Archiv der Pharmazie, 2018, DOI: 10.1002/ardp.201800290 51 Kunal Kumar Jha, Sanjay Dutta, Saibal Sar, Subhabrata Sen and Parthapratim Munshi*, Harnessing sun for catalyst and sensitize free regio- and stereo-selective [2+2] cycloaddition, Tetrahedron, 2018, doi: 10.1016/j.tet.2018.10.065 50 Jyoti Chauhan, Moumita Dasgupta, Tania Luthra, Akanksha Awasthi, Sayantan Tripathy, Anindyajit Banerjee, Santunu Paul, Debashish Nag, Saikat Chakrabarti, Gopal Chakrabarti and Subhabrata Sen*, Design, synthesis and biological evaluation of a novel library of antimitotic C2-aroyl/arylimino tryptamine derivatives that are also potent inhibitors of indoleamine-2, 3-dioxygenase (IDO), European Journal of Pharmaceutical Chemistry, 2018, doi:10.1016/j.ejps.2018.08.033 49 Tania Luthra, K. Naga Lalitha, A. Uma and Subhabrata Sen*, Design, synthesis and in vitro study of densely functionalized oxindoles as potent -glucosidase inhibitors. Just accepted, Bioorganic and Medicinal Chemistry, 2018, doi.org/10.1016/j.bmc.2018.08.022 48 Pratip Dutta and Subhabrata Sen*, (Benz)Imidazole directed cobalt (III) catalysed C-H activation of Arenes: A facile strategy to access polyheteroarenes via oxidative annulation. European Journal of Organic Chemistry, 2018, doi: 10.1002/ejoc.201801056. 47 Jyoti Chauhan, Tania Luthra and Subhabrata Sen*, An iodine catalyzed metal free oxidative ring opening of 1-aryltetrahydro--carbolines: Facile synthesis of C2 aroyl and aryl methanimino indole derivatives. European Journal of Organic Chemistry, 2018, 10.1002/ejoc.201800879 46 Pratip Dutta, Basabbijayi Dhar and Subhabrata Sen*, Aerobic oxidative amidation of alkynes using titanium oxide encapsulated cuprous iodide nanoparticles (CuI@TiO2). New Journal of Chemistry, 2018, 42, 12062 45 Chandramohan Bathula, Catarina Roma-Rodrigues, Jyoti Chauhan, Alexandra R. Fernandes* and Subhabrata Sen*, Synthesis of tetrahydro-1H-indolo[2, 3- b]pyrrolo[3, 2-c]quinolones via intramolecular oxidative ring rearrangement of tetrahydro-b-carbolines and their biological evaluation. New Journal of Chemistry, 2018, DOI: 10.1039/C7NJ04616B. 44 Pratip K. Dutta, Subhabrata Sen,* Debasree Saha* and Basabbijayi Dhar, Solid Supported nano structured Cu-Catalyst for solvent/ligand free C2 Amination of Azoles, Eur. J. Org. Chem. 2017, DOI: 10.1002/ejoc.201701669. 43 Jyoti Chauhan, Tania Luthra, Rambabu Gundla, Antonio Ferraro, Ulrike Holzgrabe, Subhabrata Sen*, A diversity oriented synthesis of natural product inspired molecular libraries. Organic and Biomolecular Chemistry, 2017, 15, 9108-9120. 42 Tania Luthra, Rahul Agarwal, Uma Adepally,* Mamidala, Estari, Subhabrata Sen* A novel library of a-arylketones as potential inhibitors of a-glucosidase: Their design, synthesis, in vitro and in vivo studies, Scientific Reports, 2017, 7, 13246 (DOI:10.1038/s41598-017-13798-y). 41 Santanu Hati, Ulrike Holzgrabe, Subhabrata Sen* Oxidative dehydrogenation of C-C and C-N bonds: A convenient approach to access diverse (dihydro) heteromatic compound, Beilstein J. Org. Chem. 2017, 13, 1670-1692. 40 Suresh Poudapally, Shankar Battu, Loka Reddy Velatooru, Murali Satyanarayana Bethu, Janapala Venkateswara Rao, Somesh Sharma, Subhabrata Sen, Narender Pottabathini, Vijaya Bhaskara Reddy Iska, Vidya Katangoor, Synthesis and Biological Evaluation of Novel Quinazoline-Sulfonamides as Anti-Cancer Agents, Bioorganic and Medicinal Chemistry Letters, 2017, doi.org/10.1016/j.bmcl.2017.03.042 39 Santanu Hati and
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