KAJIMA’s Engineering Approach targeted for Large-scale Plant Factory and Advanced Facility for Plant-Made Pharmaceuticals
November 29, 2016 Mariko Hayakumo Kajima Corporation
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Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Chapter 1 Today’s overview
• Kajima Corporation Profile • Main achievements on Plant Factory • 3 Component Technologies • Next Plan in North America
Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Kajima Corporation Profile
• Corporate Data
• Global Network
• Kajima USA overview
• Organization chart
• Engineering Target Areas
• Multiple Specialities
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Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Corporate Data
KAJIMA Corporation
Kajima Corporation Founded in 1840
Over 12,000 Employees Worldwide
2015 Annual Revenue of $15.8 Billion
# 9 ENR Top International Contractors
Primary Operations in Japan, Asia, US, & Europe Tokyo Headquarters
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Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Global Network
Kajima Europe LTD.(KEL) Kajima Poland Sp.z o.o(KPO) Kajima Czech Design and Construction S.R.O.(KCDC) The Austin Company Kajima Associates,Inc. Kajima Building & Tokyo KCS WEST,Inc. Design Group, Inc. Kajima U.S.A. Kajima Corporation BATSON-COOK COMPANY Headquarters (China) CO.,LTD. Hawaiian Dredging Construction,Inc. Kajima Alberici Mexico. Gurgaon Bangkok Manila Kajima Overseas Asia PTE LTD (KOA)
Jakarta
Kajima Australia
Principal Overseas Subsidiaries and Affiliates
We have a network of overseas subsidiaries and affiliates in North America, Asia and Europe providing building construc- tion and/or real estate development business. 5
Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Kajima USA overview
KAJIMA USA
Kajima USA Celebrating 52 Years in the US
Headquartered in Atlanta, GA
$2 Billion Average Annual Revenue
Over 1,000 Employees
10 Design, Construction, & Real Estate Companies Mitsubishi Power Systems Heavy Industrial Manufacturing Facility 6
Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Organization chart
Kajima U.S.A. Group Organization
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Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Engineering Target Areas
Pharmaceutical factories Food/Cosmetic Chemical Plants
Pharmaceutical Plant factories Research laboratories
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Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Section 3 Multiple Specialities
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Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Chapter 2 Main Achievements
• Large-scale plant factory • Advanced Laboratory for PMPs • Case for the production of PMPs in Japan
Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Main Achievements
Large-scale Plant Factory Advanced Laboratory for Plant-made Pharmaceuticals (hereinafter PMPs)
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Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Achievement Large-scale plant factory
Mirai Co., Ltd.
“Mirai Tagajo greenroom”
Wolrd’s largest-scale plant factory equipped with full LED
・Renovated the electronic device factory ・Enables stable plant production with HVAC system featuring cultivation environment-simulation technology
Contents: Facility design /construction Cultivation rack system
Production scale:10000pcs/day
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Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Achievement Large-scale plant factory
JA Tozai Shirakawa Mitsui Fudosan Co. “Miryoku manten vegetable house” “Kashiwa no ha 2nd green room”
Contents: Cultivation rack system Contents: Cultivation rack system Production scale:3,000pcs/day Production scale:10,000pcs/day
Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Achievement Large-scale plant factory
Others NYK Trading Corporation “Tsuruga Plant Factory”
Contents: Facility design Production scale:3,000pcs/day
Achievement for plant factory plan : Overseas Project Total 46,000pcs/day SCATIL (Hong Kong ) Contents: Facility basic design / Cultivation rack system Production scale:3,000pcs/day
KGPP (Russia ) Contents: Facility basic design Production scale:10,000pcs/day
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Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Achievement Advanced Laboratory for PMPs
Achievements of all 2 genetically modified plant factories in Japan
Advanced Industrial Science and Technology (AIST), Northern Advancement Center for Science & Technology Hokkaido center (NOASTEC) Closed Type Plant Production System for PMPs Green Chemical Laboratory (Design/Construction : Feb. 2007 Completion) (Design/Construction : Dec. 2012 Completion)
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Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Achievement Closed type plant production system for PMPs (AIST Hokkaido center)
The most advanced system to conduct consistently the process from “Production, growth and culture of genetically modified plants” to “extraction, purification and preparation of useful substance” 20
Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Achievement Case for the production of PMPs in Japan
Hokusan Co., Ltd.
“InterBerry α”
• Veterinary Medical Product to Alleviation of gingivitis for dogs made from genetic recombination strawberries ex- pressing interferon α
• The first approved pharmaceutical products made from plants themselves in the world (2013)
• Production at the closed plant factory for PMPs in AIST
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Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Chapter 3 3 Component Technologies
• Key factors of Kajima’s Engineering • Planning technology understood plant physiology
• Facility for high-value added plants production
Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Section 1 3 Component Technologies
Key factors of Planning Facility for Kajima’s technology high-value Engineering understood added plants plant physiology production
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Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Key factors of Kajima’s Engineering
Cultivation system plan Energy saving ・Cultivation rack plan suited for kinds of crops • Optimization of cultivation lighting ・Lighting for cultivation • HVAC plan ・Nutrient solution system • Utilization of Green energy ・Environment monitoring system • Controlled Environment system ・CO2 enrichment system • Water treatment ・Durability design etc.
Automation Hygienic management Automated • Technical consultation for daily hygienic management Material handling • Sterilization technology of cultivation space and system hydroponic system
Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Planning technology understood plant physiology
Understanding plant physiology Utilization of plant cultivation Ex. Photosynthetic, Transpiration, environmental simulation Nutrient Physiology
Plant Scientist joins the project
Research Institute for R&D since 1949 ・Collaborative R&D ・Supports for outside organizations
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Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Facility for high-value added plants production
Totalize cultivation process and • GMP Compliance pharmaceutical process • Cartagena Law support • Containment technology
Joint research with the leading runner on PMPs in Japan 2007-2011, 2011-2015 METI
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Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Chapter 4 Next Plan in North America
• Project structure • Case Study
Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. EPCM Project structure
Finding Basic Design Procurement Construction Issues Planning Phase Phase Consulting Phase Phase
Kajima Engineering team Specific technical supports
K.B.D.G
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Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Section 2 Case Study
Q1: We are interested in plant factory. How should we do? Which kinds of plants is it produced by plant factory?
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Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Q1: We are interested in plant factory. How should we do? Which kinds of plants is it produced by plant factory?
A1: Kajima propose the various cultivable plants by the collaboration between Kajima and cultivators who have cultivation know-how (leaves, fruits and edible flowers etc.) and plant factory basic plan designed for plant species.
Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Section 3 Case Study
Q2:We would like to build the plant factory can harvest tens of thousands of lettuce per day. We would like to produce local food by using the existing area or facility.
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Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Q2:We would like to build the plant factory can harvest tens of thousands of lettuce per day. We would like to produce local food by using the existing land.
A2: Kajima propose the efficient facility plan suited for client’s requirements. It is possible for the facility design suited for the actual operation plan, estimation of production scale and also automated material handling system.
Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Section 4 Case Study
Q3:We would like to plan the cultivation facility and pharmaceutical facility for the production of plant made vaccine (PMPs).
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Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved. Q3:We would like to plan the cultivation facility and pharmaceutical facility for the production of plant made vaccine (PMPs).
A3: Kajima design the facility plan to utilize cultivation process and pharmaceutical process. We manage GMP compliance if it is necessary.
Copyright (C) 2016 KAJIMA CORPORATION All Rights Reserved.