DOCSLIB.ORG

Sensorimotor Modulations by Cognitive Processes During Accurate Speech Discrimination: an EEG Investigation of Dorsal Stream Processing David E

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Sensorimotor Modulations by Cognitive Processes During Accurate Speech Discrimination: an EEG Investigation of Dorsal Stream Processing David E University of Tennessee Health Science Center UTHSC Digital Commons Theses and Dissertations (ETD) College of Graduate Health Sciences 5-2018 Sensorimotor Modulations by Cognitive Processes During Accurate Speech Discrimination: An EEG Investigation of Dorsal Stream Processing David E. Jenson University of Tennessee Health Science Center Follow this and additional works at: https://dc.uthsc.edu/dissertations Part of the Speech and Hearing Science Commons, and the Speech Pathology and Audiology Commons Recommended Citation Jenson, David E. (http://orcid.org/https://orcid.org/0000-0002-1007-8579), "Sensorimotor Modulations by Cognitive Processes During Accurate Speech Discrimination: An EEG Investigation of Dorsal Stream Processing" (2018). Theses and Dissertations (ETD). Paper 455. http://dx.doi.org/10.21007/etd.cghs.2018.0449. This Dissertation is brought to you for free and open access by the College of Graduate Health Sciences at UTHSC Digital Commons. It has been accepted for inclusion in Theses and Dissertations (ETD) by an authorized administrator of UTHSC Digital Commons. For more information, please contact [email protected]. Sensorimotor Modulations by Cognitive Processes During Accurate Speech Discrimination: An EEG Investigation of Dorsal Stream Processing Document Type Dissertation Degree Name Doctor of Philosophy (PhD) Program Speech and Hearing Science Track Speech and Language Pathology Research Advisor Tim Saltuklaroglu, Ph.D. Committee Andrew L. Bowers, Ph.D. Devin Casenhiser, Ph.D. Ashley W. Harkrider, Ph.D. Kevin J. Reilly, Ph.D. ORCID http://orcid.org/https://orcid.org/0000-0002-1007-8579 DOI 10.21007/etd.cghs.2018.0449 This dissertation is available at UTHSC Digital Commons: https://dc.uthsc.edu/dissertations/455 Sensorimotor Modulations by Cognitive Processes During Accurate Speech Discrimination: An EEG Investigation of Dorsal Stream Processing A Dissertation Presented for The Graduate Studies Council The University of Tennessee Health Science Center In Partial Fulfillment Of the Requirements for the Degree Doctor of Philosophy From The University of Tennessee By David E. Jenson May 2018 Copyright © 2018 by David E. Jenson. All rights reserved. ii DEDICATION This dissertation is dedicated to my wife Allison and my daughters Norah, Callie, and Eve. Thank you for your love, encouragement, and support. You have sustained me through this process, and I would not have been able to do this without you. iii ACKNOWLEDGEMENTS I would like to thank Dr. Tim Saltuklaroglu for his mentorship and guidance. I appreciate the time and effort that he has invested in both my academic and personal development. I am grateful for the deft hand that he has displayed as he has nurtured me towards academic independence. I would like to thank my committee members, Dr. Ashley W. Harkrider, Dr. Devin Casenhiser, Dr. Kevin J. Reilly, and Dr. Andrew L. Bowers for their support and guidance during my doctoral training. I have appreciated their advice, critiques, and thoughtful questions that have shaped the development of this manuscript. I would like to thank David Thornton for being a steady compatriot and invaluable resource through this process. He has given up countless hours to assist me with data collection, brainstorming sessions, manuscript review, and other tasks that brought him no direct benefit. I am grateful for the camaraderie and support, which have provided much needed levity along the way. I would like to thank the Graduate College at the University of Tennessee Health Science Center for providing financial support towards my completion of the Ph.D. program. I would like to acknowledge Blake Rafferty for his assistance with data collection for this project. And a final thank you to my parents. Thank you for championing curiosity and instilling a love of puzzles when I was young. iv ABSTRACT Internal models mediate the transmission of information between anterior and posterior regions of the dorsal stream in support of speech perception, though it remains unclear how this mechanism responds to cognitive processes in service of task demands. The purpose of the current study was to identify the influences of attention and working memory on sensorimotor activity across the dorsal stream during speech discrimination, with set size and signal clarity employed to modulate stimulus predictability and the time course of increased task demands, respectively. Independent Component Analysis of 64– channel EEG data identified bilateral sensorimotor mu and auditory alpha components from a cohort of 42 participants, indexing activity from anterior (mu) and posterior (auditory) aspects of the dorsal stream. Time frequency (ERSP) analysis evaluated task- related changes in focal activation patterns with phase coherence measures employed to track patterns of information flow across the dorsal stream. ERSP decomposition of mu clusters revealed event-related desynchronization (ERD) in beta and alpha bands, which were interpreted as evidence of forward (beta) and inverse (alpha) internal modeling across the time course of perception events. Stronger pre-stimulus mu alpha ERD in small set discrimination tasks was interpreted as more efficient attentional allocation due to the reduced sensory search space enabled by predictable stimuli. Mu-alpha and mu- beta ERD in peri- and post-stimulus periods were interpreted within the framework of Analysis by Synthesis as evidence of working memory activity for stimulus processing and maintenance, with weaker activity in degraded conditions suggesting that covert rehearsal mechanisms are sensitive to the quality of the stimulus being retained in working memory. Similar ERSP patterns across conditions despite the differences in stimulus predictability and clarity, suggest that subjects may have adapted to tasks. In light of this, future studies of sensorimotor processing should consider the ecological validity of the tasks employed, as well as the larger cognitive environment in which tasks are performed. The absence of interpretable patterns of mu-auditory coherence modulation across the time course of speech discrimination highlights the need for more sensitive analyses to probe dorsal stream connectivity. v TABLE OF CONTENTS CHAPTER 1. INTRODUCTION .....................................................................................1 CHAPTER 2. LITERATURE REVIEW .........................................................................7 The Dorsal Stream ...........................................................................................................7 Necessity of Considering Cognitive Processes in Speech Perception .............................7 Attentional Modulation of Dorsal Stream Activity in Speech Perception .....................10 Predictive Coding Contributions to Attention ...........................................................10 Inhibitory Contributions to Attention ........................................................................13 Working Memory Contributions to Dorsal Stream Activity in Speech Perception ......15 Electroencephalography and the Mu Rhythm ...............................................................17 Mu Alpha ...................................................................................................................18 Mu Beta ......................................................................................................................19 Internal Modeling in Speech Perception ........................................................................22 Pre-stimulus Beta and Predictability ..........................................................................23 Early Alpha ERS and Inhibitory Control ...................................................................25 Late Mu Activity and Covert Rehearsal ....................................................................27 Auditory Alpha as an Index of Posterior Dorsal Stream Activity .................................30 Connectivity Across the Dorsal Stream in Speech Perception ......................................33 CHAPTER 3. METHODOLOGY ..................................................................................36 Participants .....................................................................................................................36 Stimuli ............................................................................................................................36 Design ............................................................................................................................37 Procedures ......................................................................................................................37 Neural Data Acquisition ................................................................................................38 Data Processing ..............................................................................................................40 Pre-processing ............................................................................................................40 Independent Component Analysis .............................................................................41 Dipole Localization ....................................................................................................41 Study Module .............................................................................................................41 PCA Clustering ..........................................................................................................42
Load more

Recommended publications
  • Motor Development Research: II
    Motor development research: II. The first two decades of the 21st century shaping our future Jill Whitall1, Farid Bardid2,3, Nancy Getchell4, Melissa Pangelinan5, Leah E. Robinson6,7, Nadja Schott8, Jane E. Clark9,10 1 Department of Physical Therapy & Rehabilitation Science, University of Maryland, USA 2 School of Education, University of Strathclyde, UK 3 Department of Movement and Sports Sciences, Ghent University, Belgium 4 Department of Kinesiology & Applied Physiology, University of Delaware, USA 5 School of Kinesiology, College of Education, Auburn University, USA 6 School of Kinesiology, University of Michigan, USA 7 Center for Human Growth and Development, University of Michigan, USA 8 Institute of Sport & Exercise Science, University of Stuttgart, Germany 9 Department of Kinesiology, School of Public Health, University of Maryland, USA 10 Neuroscience and Cognitive Science Program, University of Maryland, USA Corresponding author: Jill Whitall E-mail: [email protected] This is the accepted manuscript version of the study cited as: Whitall, J., Bardid, F., Getchell, N., Pangelinan, M., Robinson, L. E., Schott, N., & Clark, J. E. (2020). Motor development research: II. The first two decades of the 21st century shaping our future. Journal of Motor Learning and Development, 8(2), 363-390. https://doi.org/10.1123/jmld.2020-0007 This paper is not the copy of record and may not exactly replicate the authoritative document published in Journal of Motor Learning and Development. The final published version is available on the journal website. Author note: Authorship order is alphabetical except the lead author is first and the senior author is last. Abstract In Part I of this series (Whitall et al., this issue), we looked back at the 20th century and re- examined the history of Motor Development research described in Clark & Whitall’s 1989 paper “What is Motor Development? The Lessons of History”.
    [Show full text]
  • Electroencephalography (Eeg) and Its Use in Motor Learning And
    ELECTROENCEPHALOGRAPHY (EEG) AND ITS USE IN MOTOR LEARNING AND CONTROL by Tyler Thorley Whittier July, 2017 Director of Thesis: Dr. Nicholas Murray Major Department: Kinesiology Electroencephalography (EEG) is a non-invasive technique of measuring electric currents generated from active brain regions and is a useful tool for researchers interested in motor control. The study of motor learning and control seeks to understand the way the brain understands, plans and executes movement both physical and imagined. Thus, the purpose of this study was to better understand the ways in which electroencephalography can be used to measure regions of the brain involved with motor control and learning. For this purpose, two independent studies were completed using EEG to monitor brain activity during both executed and imagined actions. The first study sought to understand the cognitive demand of altering a running gait and provides EEG evidence of motor learning. 13 young healthy runners participated in a 6-week in-field gait-retraining program that altered running gait by increasing step rate (steps per minute) by 5-10%. EEG was collected while participants ran on a treadmill with their original gait as a baseline measurement. After the baseline collection, participants ran for one minute at the same speed with a 5-10% step rate increase while EEG was collected. Participants then participated in a 6-week in-field gait-retraining program in which they received bandwith feedback while running in order to learn the new gait. After completing the 6-week training protocol, participants returned to the lab for post training EEG collection while running with the new step rate.
    [Show full text]
  • Stroke Rehabilitation Through Motor Imagery Controlled Humanoid
    Stroke Rehabilitation through Motor Imagery controlled Humanoid (Submitted in requirement of undergraduate Departmental honors) Priya Rao Chagaleti Computer Science and Engineering University of Washington 17th June 2013 Thesis advisor: Prof. Rajesh P. N. Rao Acknowledgements I gratefully acknowledge the help and encouragement from Melissa Smith, Alex Dadgar, Matthew Bryan, Jeremiah Wander, Sam Sudar and Chantal Murthy in execution of this project. Acronyms ALS: Amyotrophic lateral sclerosis BCI : Brain Computer Interface BCI2000: BCI software EEG: Electro encephalogram EMG: Electromyogram EOG: Electrooculogram ECOG: Electrocorticograph ERP: Event related potential ERD: Event related desynchronization ERS: Event related synchronization MEG: Magnetoencephalogram fMRI: functional Magnetic resonance imaging SCP: Slow cortical potential SNR: Signal to noise ratio SMR: Sensory motor rhythm 1 Abstract Rehabilitation of individuals who are motor-paralyzed as a result of disease or trauma is a challenging task because each individual patient presents with a different set of clinical findings and in varying states of physical and mental well-being. The only commonality is motor paralysis. It may be the paralysis of a single limb or paralysis of all four limbs and may include paralysis of facial muscles or respiratory muscles amongst other motor disabilities. Each patient requires individualized management. Rehabilitation of these patients includes the use of mechanical assistance devices to perform daily chores such as lifting an object or closing a door. This project intended to use a humanoid robot to do these tasks using brain signals from the sensory motor cortex, the mu-rhythm, which would be programmed to convert the relevant brain signals into a command signal for the robot using a non-invasive brain-computer interface (BCI).
    [Show full text]
  • Neural Activity Based Biofeedback Therapy for Autism Spectrum
    Neural Activity based Biofeedback Therapy for Autism Spectrum Disorder through Wearable Wireless Textile EEG Monitoring System Ahna Sahi a, Pratyush Rai *b, Sechang Oh b, Mouli Ramasamy b, Robert E. Harbaugh c, Vijay K. Varadan b,c,d a Dept. Psychology, Sam Higginbottom Institute of Agriculture, Science and Technology, Allahabad, U.P. (India) 211007; b Dept. of Electrical Engineering, University of Arkansas, Fayetteville, AR (USA) 72701; c Department of Neurosurgery, College of Medicine, Pennsylvania State University, Hershey, PA (USA) 17033; d Global Institute of Nanotechnology in Engineering and Medicine Inc., Fayetteville, AR (USA) 72701 ABSTRACT Mu waves, also known as mu rhythms, comb or wicket rhythms are synchronized patterns of electrical activity involving large numbers of neurons, in the part of the brain that controls voluntary functions. Controlling, manipulating, or gaining greater awareness of these functions can be done through the process of Biofeedback. Biofeedback is a process that enables an individual to learn how to change voluntary movements for purposes of improving health and performance through the means of instruments such as EEG which rapidly and accurately 'feedback' information to the user. Biofeedback is used for therapeutic purpose for Autism Spectrum Disorder (ASD) by focusing on Mu waves for detecting anomalies in brain wave patterns of mirror neurons. Conventional EEG measurement systems use gel based gold cup electrodes, attached to the scalp with adhesive. It is obtrusive and wires sticking out of the electrodes to signal acquisition system make them impractical for use in sensitive subjects like infants and children with ASD. To remedy this, sensors can be incorporated with skull cap and baseball cap that are commonly used for infants and children.
    [Show full text]
  • The Infant Mirror Neuron System Studied with High Density EEG
    Preliminary manuscript, do not quote without permission The infant mirror neuron system studied with high density EEG Author: Nyström Pär. Dep. of Psychology, Box 1225 Uppsala University, 751 42 Uppsala, Sweden Corresponding author: Email: [email protected] Phone (46) 18 471 5752 Fax: (46) 18 471 2123 Running title: EEG of the infant mirror neuron system Keywords: EEG, ERP, mu, desynchronization, infant, mirror 1 Abstract The mirror neuron system has been suggested to play a role in many social capabilities such as action understanding, imitation, language and empathy. These are all capabilities that develop during infancy and childhood, but the human mirror neuron system has been poorly studied using neurophysiological measures. This study measured the brain activity of 6 months old infants and adults using a high density EEG net with the aim of identifying mirror neuron activity. The subjects viewed both goal directed movements and non goal directed movements. An independent component analysis was used to extract the sources of cognitive processes. The desynchronization of the mu rhythm in adults has been shown to be a marker for activation of the mirror neuron system and was used as a criterion to categorize independent components between subjects. The results show significant mu desynchronization in the adult group and significantly higher ERP activation in both adults and 6 months for the goal directed action observation condition. This study demonstrate that infants as young as 6 months display mirror neuron activity and is the first to present a direct ERP measure of the mirror neuron system in infants. 2 Acknowledgements The author acknowledges the contribution of Robert Oostenveld for making the DIPFIT software available, as well as the whole EEGLAB developer group.
    [Show full text]
  • 295538717.Pdf
    CORE Metadata, citation and similar papers at core.ac.uk Provided by TELKOMNIKA (Telecommunication Computing Electronics and Control) TELKOMNIKA, Vol.17, No.3, June 2019, pp.1149~1158 ISSN: 1693-6930, accredited First Grade by Kemenristekdikti, Decree No: 21/E/KPT/2018 DOI: 10.12928/TELKOMNIKA.v17i3.11776 1149 Significant variables extraction of post-stroke EEG signal using wavelet and SOM kohonen Esmeralda C. Djamal*1, Deka P. Gustiawan2, Daswara Djajasasmita3 1,2Department of Informatics-Universitas Jenderal Achmad Yani, Cimahi, Indonesia 3Faculty of Medicine-Universitas Jenderal Achmad Yani, Cimahi, Indonesia *Coresponding author, e-mail: [email protected] Abstract Stroke patients require a long recovery. One success of the treatment given is the evaluation and monitoring during recovery. One device for monitoring the development of post-stroke patients is Electroencephalogram (EEG). This research proposed a method for extracting variables of EEG signals for post-stroke patient analysis using Wavelet and Self-Organizing Map Kohonen clustering. EEG signal was extracted by Wavelet to obtain Alpha, beta, theta, gamma, and Mu waves. These waves, the amplitude and asymmetric of the symmetric channel pairs are features in Self Organizing Map Kohonen Clustering. Clustering results were compared with actual clusters of post-stroke and no-stroke subjects to extract significant variable. These results showed that the configuration of Alpha, Beta, and Mu waves, amplitude together with the difference between the variable of symmetric channel pairs are significant in the analysis of post-stroke patients. The results gave using symmetric channel pairs provided 54-74% accuracy. Keywords: EEG signal, post-stroke patient, significant variables, SOM clustering, wavelet Copyright © 2019 Universitas Ahmad Dahlan.
    [Show full text]
  • ARTICLE in PRESS BRESC-40614; No
    DTD 5 ARTICLE IN PRESS BRESC-40614; No. of pages: 9; 4C: Cognitive Brain Research xx (2005) xxx–xxx www.elsevier.com/locate/cogbrainres Research report EEG evidence for mirror neuron dysfunction in autism spectrum disorders Lindsay M. Obermana,b,T, Edward M. Hubbarda,b, Joseph P. McCleeryb, Eric L. Altschulera,b,c, Vilayanur S. Ramachandrana,b,d, Jaime A. Pinedad,e aCenter for Brain and Cognition, UC San Diego, La Jolla, CA 92093-0109, USA bDepartment of Psychology, UC San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0109, USA cDepartment of Rehabilitation Medicine, Mt. Sinai School of Medicine, New York, New York 10029, USA dDepartment of Neurosciences, UC San Diego, La Jolla, CA 92093-0662, USA eDepartment of Cognitive Science, UC San Diego, La Jolla, CA 92093-0515, USA Accepted 13 January 2005 Abstract Autism spectrum disorders (ASD) are largely characterized by deficits in imitation, pragmatic language, theory of mind, and empathy. Previous research has suggested that a dysfunctional mirror neuron system may explain the pathology observed in ASD. Because EEG oscillations in the mu frequency (8–13 Hz) over sensorimotor cortex are thought to reflect mirror neuron activity, one method for testing the integrity of this system is to measure mu responsiveness to actual and observed movement. It has been established that mu power is reduced (mu suppression) in typically developing individuals both when they perform actions and when they observe others performing actions, reflecting an observation/execution system which may play a critical role in the ability to understand and imitate others’ behaviors. This study investigated whether individuals with ASD show a dysfunction in this system, given their behavioral impairments in understanding and responding appropriately to others’ behaviors.
    [Show full text]
  • Wikipedia.Org/W/Index.Php?Title=Neural Oscillation&Oldid=898604092"
    Neural oscillation Neural oscillations, or brainwaves, are rhythmic or repetitive patterns of neural activity in the central nervous system. Neural tissue can generate oscillatory activity in many ways, driven either by mechanisms within individual neurons or by interactions between neurons. In individual neurons, oscillations can appear either as oscillations in membrane potential or as rhythmic patterns of action potentials, which then produce oscillatory activation of post-synaptic neurons. At the level of neural ensembles, synchronized activity of large numbers of neurons can give rise to macroscopic oscillations, which can be observed in an electroencephalogram. Oscillatory activity in groups of neurons generally arises from feedback connections between the neurons that result in the synchronization of their firing patterns. The interaction between neurons can give rise to oscillations at a different frequency than the firing frequency of individual neurons. A well-known example of macroscopic neural oscillations is alpha activity. Neural oscillations were observed by researchers as early as 1924 (by Hans Berger). More than 50 years later, intrinsic oscillatory behavior was encountered in vertebrate neurons, but its functional role is still not fully understood.[1] The possible roles of neural oscillations include feature binding, information transfer mechanisms and the generation of rhythmic motor output. Over the last decades more insight has been gained, especially with advances in brain imaging. A major area of research in neuroscience involves determining how oscillations are generated and what their roles are. Oscillatory activity in the brain is widely observed at different levels of organization and is thought to play a key role in processing neural information.
    [Show full text]
  • Resting EEG in Psychosis and At-Risk Populations — a Possible Endophenotype?
    Schizophrenia Research 153 (2014) 96–102 Contents lists available at ScienceDirect Schizophrenia Research journal homepage: www.elsevier.com/locate/schres Resting EEG in psychosis and at-risk populations — A possible endophenotype? Siri Ranlund a,⁎, Judith Nottage b, Madiha Shaikh b,c, Anirban Dutt b,MiguelConstanted,MurielWalshea,b, Mei-Hua Hall e, Karl Friston f,RobinMurrayb,ElviraBramona,b a Mental Health Sciences Unit & Institute of Cognitive Neuroscience, University College London, W1W 7EJ, United Kingdom b NIHR Biomedical Research Centre for Mental Health at the South London and Maudsley NHS Foundation Trust and Institute of Psychiatry, Kings College London, WC2R 2LS, United Kingdom c Department of Psychology, Royal Holloway, University of London, TW20 0EX, United Kingdom d Psychiatry Department, Hospital Beatriz Ângelo, 2674-514 Loures, Lisbon, Portugal e Psychology Research Laboratory, Harvard Medical School, McLean Hospital, Belmont, MA 02478, USA f The Wellcome Trust Centre for Neuroimaging, University College London, WC1N 3BG, United Kingdom article info abstract Article history: Background: Finding reliable endophenotypes for psychosis could lead to an improved understanding Received 21 May 2013 of aetiology, and provide useful alternative phenotypes for genetic association studies. Resting quantitative Received in revised form 25 November 2013 electroencephalography (QEEG) activity has been shown to be heritable and reliable over time. However, Accepted 27 December 2013 QEEG research in patients with psychosis has shown inconsistent
    [Show full text]
  • Brain-Computer Interface for Physically Impaired People
    American University in Cairo AUC Knowledge Fountain Theses and Dissertations 2-1-2016 Brain-computer interface for physically impaired people Nourhan Shamel El Sawi Follow this and additional works at: https://fount.aucegypt.edu/etds Recommended Citation APA Citation El Sawi, N. (2016).Brain-computer interface for physically impaired people [Master’s thesis, the American University in Cairo]. AUC Knowledge Fountain. https://fount.aucegypt.edu/etds/318 MLA Citation El Sawi, Nourhan Shamel. Brain-computer interface for physically impaired people. 2016. American University in Cairo, Master's thesis. AUC Knowledge Fountain. https://fount.aucegypt.edu/etds/318 This Thesis is brought to you for free and open access by AUC Knowledge Fountain. It has been accepted for inclusion in Theses and Dissertations by an authorized administrator of AUC Knowledge Fountain. For more information, please contact [email protected]. The American University in Cairo School of Sciences and Engineering Brain-Computer Interface for Physically Impaired People By Nourhan Shamel El Sawi A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science in Robotics, Control and Smart Systems Under supervision of: Dr. Maki Habib Professor, Department of Mechanical Engineering August, 2016 DECLARATION I declare that this thesis is my work and that all used references have been cited and properly indicated. Nourhan Shamel DEDICATION I dedicate my thesis dissertation work to my family. A special feeling of gratitude to my loving parents Shamel El Sawi and Hanan Baligh for their continuous support, mom and dad you have always pushed me forward and believed in me.
    [Show full text]
  • Brain Computer Interfaces for Brain Acquired Damage
    ADVERTIMENT. Lʼaccés als continguts dʼaquesta tesi queda condicionat a lʼacceptació de les condicions dʼús establertes per la següent llicència Creative Commons: http://cat.creativecommons.org/?page_id=184 ADVERTENCIA. El acceso a los contenidos de esta tesis queda condicionado a la aceptación de las condiciones de uso establecidas por la siguiente licencia Creative Commons: http://es.creativecommons.org/blog/licencias/ WARNING. The access to the contents of this doctoral thesis it is limited to the acceptance of the use conditions set by the following Creative Commons license: https://creativecommons.org/licenses/?lang=en BRAIN COMPUTER INTERFACES FOR BRAIN ACQUIRED DAMAGE MARC SEBASTIÁN ROMAGOSA DOCTORAL THESIS PHD IN NEUROSCIENCE 2020 DIRECTOR Esther Udina i Bonet DIRECTOR Rupert Ortner DIRECTOR AND TUTOR Xavier Navarro Acebes Medical Physiology Unit Department of Cellular Biology, Physiology and Immunology Neuroscience Institute Universitat Autònoma de Barcelona MARC SEBASTIÁN ROMAGOSA BCI FOR BRAIN ACQUIRED DAMAGE Per a la meva dona, la Núria i els meus fills, l’Andreu i l’Agnès, sense vosaltres res de tot això val la pena. 2 | P a g e MARC SEBASTIÁN ROMAGOSA BCI FOR BRAIN ACQUIRED DAMAGE Acknowledgments First, I would like to thank Dr. Rupert Ortner for his constant support and advice during this time, by his side I have been able to learn every day. He has been a good boss, a good partner, and a good colleague. These special thanks also go to Dr. Esther Udina for her patience and help from the beginning, for so many hours spent and always having a word of encouragement and trusting me. I am also grateful to Dr.
    [Show full text]
  • Mu Wave Suppression During the Perception of Meaningless Syllables
    G Model NSY 3299 1–6 ARTICLE IN PRESS Neuropsychologia xxx (2009) xxx–xxx Contents lists available at ScienceDirect Neuropsychologia journal homepage: www.elsevier.com/locate/neuropsychologia 1 Mu wave suppression during the perception of meaningless syllables: 2 EEG evidence of motor recruitment ∗ 3 Stephen Crawcour, Andrew Bowers, Ashley Harkrider, Tim Saltuklaroglu 4 Department of Audiology and Speech Language Pathology, University of Tennessee, 553 S. Stadium Hall, Knoxville, TN 37996-0740, United States 5 6 article info abstract 7 8 Article history: Motor involvement in speech perception has been recently studied using a variety of techniques. In the 9 Received 11 December 2008 current study, EEG measurements from Cz, C3 and C4 electrodes were used to examine the relative power 10 Received in revised form 16 April 2009 of the mu rhythm (i.e., 8–13 Hz) in response to various audio-visual speech and non-speech stimuli, as 11 Accepted 3 May 2009 suppression of these rhythms is considered an index of ‘mirror neuron’ (i.e., motor) activity. Fourteen 12 Available online xxx adult native English speaking females watched and listened to nine audio-video stimuli clips assembled 13 from three different auditory stimuli (speech, noise, and pure tone) combined with three different video 14 Keywords: stimuli (speech, noise, and kaleidoscope—made from scrambling an image from the visual speech). Rel- 15 Mirror neuron 16 Speech perception ative to the noise–noise (baseline condition), all visual speech conditions resulted in significant levels of 17 Electroencephalography suppression, a finding that is consistent with previous reports of mirror activity to visual speech and mu 18 Syllables suppression to ‘biological’ stimuli.
    [Show full text]