DOCSLIB.ORG

Recommendations for Echocardiography Use in The

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Recommendations for Echocardiography Use in The European Journal of Echocardiography (2010) 11, 461–476 RECOMMENDATIONS doi:10.1093/ejechocard/jeq045 Recommendations for echocardiography use in the diagnosis and management of cardiac sources of embolism European Association of Echocardiography (EAE) (a registered branch of the ESC) Downloaded from Mauro Pepi 1*,ArturoEvangelista2, Petros Nihoyannopoulos 3, Frank A. Flachskampf 4, 5 6 7 8 George Athanassopoulos , Paolo Colonna , Gilbert Habib , E. Bernd Ringelstein , ejechocard.oxfordjournals.org Rosa Sicari 9, and Jose Luis Zamorano 10 on behalf of the European Association of Echocardiography Document Reviewers: Marta Sitges a and Pio Caso b 1Centro Cardiologico Monzino, IRCCS, Department Cardiovascular Sciences, University of Milan, Via Parea 4, 20138 Milan, Italy; 2Hospital Vall d’Hebron, Barcelona, Spain; 3Hammersmith Hospital, London, UK; 4University of Erlangen, Erlangen, Germany; 5Onassis Cardiac Surgery Center, Athens, Greece; 6Division of Cardiology, Policlinico Hospital, 7 8 9 Bari, Italy; University Hospital La Timone, Marseilles, France; Department of Neurology, University Hospital Mu¨nster, Germany; Institute of Clinical Physiology, Pisa, Italy; and at Landstinget i Uppsala län on August 24, 2010 10Hospital Clı´nico San Carlos, Madrid, Spain aIstitut de Torax, Hospital Clinic Universitat de Barcelona; and bOspedale Monaldi, Napoli Received 17 February 2010; accepted after revision 5 March 2010 Embolism of cardiac origin accounts for around 15–30% of ischaemic strokes. Strokes due to cardioembolism are generally severe and early and long-term recurrence and mortality are high. The diagnosis of a cardioembolic source of stroke is frequently uncertain and relies on the identification of a potential cardiac source of embolism in the absence of significant autochthone cerebrovascular occlusive disease. In this respect, echocardiography (both transthoracic and/or transoesophageal) serves as a cornerstone in the evaluation, diagnosis, and manage- ment of these patients. A clear understanding of the various types of cardiac conditions associated with cardioembolic stroke and their intrin- sic risk is therefore very important. This article reviews potential cardiac sources of embolism and discusses the role of echocardiography in clinical practice. Recommendations for the use of echocardiography in the diagnosis of cardiac sources of embolism are given including major and minor conditions associated with the risk of embolism. ----------------------------------------------------------------------------------------------------------------------------------------------------------- Keywords Cardioembolic stroke † Transthoracic echocardiography † Transoesophageal echocardiography Introduction peripheral embolism. Stroke is the third leading cause of death in several industrial countries and cardiogenic embolism accounts Why do we need recommendations for for 15–30% of ischaemic strokes.1 –3 The diagnosis of a cardioem- the echocardiographic diagnosis and bolic source of stroke is frequently uncertain and relies on the identification of a potential cardiac source of embolism in the management of cardiac sources of absence of significant autochthonous cerebrovascular occlusive embolism? disease. In this regard, echocardiography [both transthoracic Echocardiography is commonly used for the investigation of (TTE) and/or transoesophageal (TOE)] serves as a cornerstone patients with acute stroke, transient ischaemic attack (TIA) or in the evaluation and diagnosis of these patients. However, * Corresponding author. Tel: +39 2 580021; fax: +39 2 58002287, Email: [email protected] Published on behalf of the European Society of Cardiology. All rights reserved. & The Author 2010. For permissions please email: [email protected] 462 M. Pepi et al. cardioembolic stroke is a heterogeneous entity, since a variety of Method of article and definition of levels cardiac conditions can predispose to cerebral embolism. These of recommendations cardiac conditions may be classified as major, minor, or uncertain This consensus document is based on a literature review con- risk (Table 1). The indications for and role of ultrasound techniques ducted using Medline (PubMed) for peer-reviewed publications in these diseases are not well defined. Moreover, from a pathologi- and focuses on the studies published mainly in the last 10 years. cal point of view cardioembolic sources of embolism may be classi- Publications on appropriateness reflect an ongoing effort by the fied into three distinct categories: cardiac lesions that have a authors to critically and systematically create, review, and categor- propensity for thrombus formation [i.e. thrombus formation in ize clinical conditions and situations, where diagnostic tests are the left atrial appendage (LAA) in patients with atrial fibrillation used by physicians caring for patients with a suspected of cardiac (AF)], cardiac masses (i.e. cardiac tumours, vegetations, thrombi, source of embolism. Although not intended to be entirely compre- aortic atherosclerotic plaques), and passageways within the heart hensive, the indications are meant to identify common scenarios serving as conduits for paradoxical embolization (i.e. PFO, patent encompassing the major part of contemporary practice in this foramen ovale). field. The ultimate aim of this document is to improve patient Recommendations are important in this field for several reasons. Downloaded from care and health outcomes in a cost-effective manner (whenever (1) The clinical diagnosis is now dominated by echocardiography possible) linked to clinical decision making. Availability or quality which has become the standard to evaluate these patients; of equipment or personnel may influence the choice of appropri- however, better transducers and new ultrasound modalities ate imaging procedures. These criteria are also associated with (i.e. second harmonic imaging, Doppler tissue imaging, contrast clinical judgement and practice experience. Because of the echocardiography, 3D, and others) have further improved and diverse nature of the topics and the absence of objective rating ejechocard.oxfordjournals.org expanded diagnostic capabilities. Consequently, the complemen- levels of evidence (mainly due to gaps in current knowledge in tary or alternative role of TTE and TOE may be further defined. several fields), it was not possible to provide a systematic (2) Treatment of these conditions and of ischaemic stroke has not uniform summary of recommendations in all chapters. On the only developed through the continuous advances in under- basis of all these considerations, the writing group decided to standing of the disease, but has also been reoriented by the avoid levels of recommendations and maintain only the term ‘Rec- development of new strategies and the advent of interven- ommendation’. This implies an appropriate method recommended tional techniques. for all patients with a suspected of cardiac source of embolism. (3) The today’s patient population has changed due to ageing, and increase of patients with heart failure with a significant decline at Landstinget i Uppsala län on August 24, 2010 in both rheumatic fever and rheumatic valve disease. General comments (4) The aim of these recommmendations is to provide a consensus document for the echocardiographic screening Patient evaluation and diagnosis of cardiac sources of embolism. Evidence for Ischaemic stroke or TIA may be caused by several factors such as indications to recommend echocardiography in patients with systemic hypoperfusion, in situ thrombosis or vascular or cardio- stroke, TIA, or peripheral embolism is reviewed in detail. genic embolism. Since embolism from a cardiac source accounts for 15–30% approximately of these cerebral events, a very detailed neurological and cardiac evaluation should first include Table 1 Potential cardioembolic sources the patient’s clinical presentation, even though there are several limitations in making this clinical diagnosis. Several neurological Major risk sources Minor or unclear risk and cardiac features (detailed information on the characteristics sources ................................................................................ of the clinical event, history of the patients, clinical evaluation) Atrial fibrillation Mitral valve prolapse may suggest a cardioembolic origin. Moreover, evidence of embo- Recent myocardial infarction Mitral annulus calcification lism to other organs suggests that a cardioembolic source is likely. Previous myocardial infarction (LV aneurysm) Neurological and cardiac evaluation Cardiomyopathies Calcified aortic stenosis A number of cardiac conditions have been proposed as potential Cardiac masses sources of embolism and an accurate clinical evaluation may Intracardiac thrombus Atrial septal aneurysm easily raise the suspicion of a cardioembolic even in the presence Intracardiac tumours of known structural heart disease or of clinical signs of cardiac dis- Fibroelastoma Patent foramen ovale eases (i.e. arrhythmias, heart murmurs). However, the presence of Marantic vegetations a potential cardioembolic source of embolism does not itself justify Rheumatic valve disease (mitral Giant Lambl’s excrescences the diagnosis of cardioembolic stroke or TIA, since atherosclerotic stenosis) cerebrovascular disease and cardiac disease often co-exist. The Aortic arch atheromatous plaques most frequent causes of cardiogenic stroke are AF, left ventricular Endocarditis (LV) dysfunction (congestive heart failure), valve disease and
Load more

Recommended publications
  • A Hyperdense Artery Sign and Middle Cerebral Artery Dissection
    □ CASE REPORT □ A Hyperdense Artery Sign and Middle Cerebral Artery Dissection Yusuke Yakushiji 1, Yoshinori Haraguchi 2, Shu Soejima 2, Yukinori Takase 3, Akira Uchino 3, Shunzo Koizumi 2 and Yasuo Kuroda 1 Abstract We describe a rare case of spontaneous middle cerebral artery (MCA) dissection that caused cerebral in- farction and subarachnoid hemorrhage (SAH), which also presented with a hyperdense artery sign. A hyper- dense artery sign of the MCA in acute cerebral infarction strongly indicates thromboembolic MCA occlusion, which is often treated with thrombolytic therapy. However, thrombolytic therapy for intracranial artery dissec- tions has both risks and benefits, due to the association of artery dissections with SAH. Therefore, it is im- portant to keep in mind that an MCA dissection can also cause cerebral infarction with a hyperdense artery sign, particularly in young patients presenting with headache. Key words: Hyperdense middle cerebral artery sign, Computed tomography, Intracranial artery dissection, Cerebral infarction (DOI: 10.2169/internalmedicine.45.1888) his blood pressure was 162/126 mmHg. Neurological exami- Introduction nation revealed drowsiness (Japan Coma Scale II-10), motor aphasia, and right-sided hemiplegia. National Institutes of A hyperdense artery sign of the middle cerebral artery Health Stroke Scale (NIHSS) was 15. Laboratory examina- (MCA) in acute cerebral infarction strongly indicates throm- tions were normal, including α1-antitrypsin level and hemat- boembolic MCA occlusion (1), which is often treated with ocrit (45.9%). thrombolytic therapy (2). However, dissection of the intra- Brain computed tomography (CT), performed on admis- cranial cerebral arteries can cause a subarachnoid hemor- sion (Day 1), showed a hyperdensity at the M1 segment rhage (SAH), as well as cerebral infarction (3);therefore, through to the posterior trunk of the M2 segment of the left thrombolytic therapy is generally not indicated in such middle cerebral artery (MCA) (Fig.
    [Show full text]
  • “Comparison of Clinical Stroke Scores and Ct Brain
    “COMPARISON OF CLINICAL STROKE SCORES AND CT BRAIN IN THE DIAGNOSIS OF INTRACEREBRAL HAEMORRHAGE AND INFARCT IN ACUTE STROKE PATIENTS” Dissertation submitted to The Tamil Nadu Dr.M.G.R. Medical University In partial fulfillment of the regualtions for The award of the degree of M.D. General Medicine [Branch – 1] K.A.P.VISWANATHAM GOVERNMENT MEDICAL COLLEGE & M.G.M. GOVERNMENT HOSPITAL, TIRUCHIRAPPALLI. THE TAMIL NADU DR.M.G.R. MEDICAL UNIVERSITY CHENNAI 2016 CERTIFICATE This is to certify that the dissertation entitled “COMPARISON OF CLINICAL STROKE SCORES AND CT BRAIN IN THE DIAGNOSIS OF INTRACEREBRAL HAEMORRHAGE AND INFARCT IN ACUTE STROKE PATIENTS” is a bonafide original work of Dr. RAMYAPRASAD in partial fulfillment of the requirements of M.D., General Medicine [Branch- 1] examination of THE TAMILNADU Dr. M. G. R. MEDICAL UNIVERSITY to be held in April 2016. Prof.Dr.P.KANAGARAJ.M.D Prof.Dr.M.K.MURALIDHARAN.M.S.,Mch HOD & UNIT-1 CHIEF DEAN Department of Medicine K.A.P.V. Govt. Medical College K.A.P.V. Govt. Medical College M.G.M. Govt. Hospital, M.G.M. Govt. Hospital, Tiruchirappalli. Tiruchirappalli. 2 DECLARATION I Solemnly declare that the dissertation titled “COMPARISON OF CLINICAL STROKE SCORES AND CT BRAIN IN THE DIAGNOSIS OF INTRACEREBRAL HAEMORRHAGE AND INFARCT IN ACUTE STROKE PATIENTS” is done by me at K.A.P. VISWANATHAM GOVT MEDICAL COLLEGE, TIRUCHIRAPPALLI under the guidance and supervision of Prof. Dr. P. KANAGARAJ. M.D., This dissertation is submitted to The Tamilnadu Dr. M.G.R. Medical University towards the partial fulfillment of requirements for the award of M.D Degree (Branch-1) in General Medicine.
    [Show full text]
  • Downloaded on the Device
    )NSIGHTSª)MAGINGª ªª3UPPLª 3n3ª $/)ªS ª Postgraduate Educational Programme Categorical Courses (CC) EFOMP Workshop (EF) ESR meets Sessions (EM) European Excellence in Education (E³) Honorary Lectures (HL) Mini Courses (MC) Multidisciplinary Sessions (MS) New Horizons Sessions (NH) Opening Lecture (OL) Professional Challenges Sessions (PC) Refresher Courses (RC) RTF - Radiology Trainees Forum (TF) Special Focus Sessions (SF) State of the Art Symposia (SA) " # # !"# "# # A B C D E F G S1 !"!"! " # A B C D E F G S2 !"!"! 12:30 - 13:30 Room E2 Learning Objectives: 1. To understand the indications for percutaneous image-guided biopsy. The Beauty of Basic Knowledge: Skeletal Radiology 2. To learn about the practical aspects of biopsy, needle selection and guidance techniques. MC 26 A 3. To learn how to approach difficult lesions and avoid complications. Plain radiographs: analysis and 14:00 - 15:30 Room C interpretation Interactive Teaching Session Moderator: V.N. Cassar-Pullicino; Oswestry/UK E³ 220 A-001 12:30 The treated breast: what you need to know Plain radiographs: analysis and interpretation I. McCall; Devon/UK ([email protected]) A-003 14:00 A. Imaging after treatment of breast cancer The radiograph remains a quick and inexpensive imaging modality. Factors to M.H. Fuchsjäger; Graz/AT ([email protected]) Thursday evaluate include the thickness and outlines of cortical bone, the density and pattern of trabecular bone and the presence or absence of periosteal new Imaging after treatment of breast cancer is for confirmation of lesion removal, bone. The position of lesions within the bone, their outline, size and margin and identification of postprocedural fluid collections, detection of residual or whether they are single or multiple also provide important diagnostic recurrent cancer and screening for metachronous cancers.
    [Show full text]
  • Oxford Textbook of Neuroimaging
    Oxford Textbook of Neuroimaging Edited by Massimo Filippi Neuroimaging Research Unit, and Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy Series Editor Christopher Kennard 1 1 Great Clarendon Street, Oxford, OX2 6DP, United Kingdom Oxford University Press is a department of the University of Oxford. It furthers the University’s objective of excellence in research, scholarship, and education by publishing worldwide. Oxford is a registered trade mark of Oxford University Press in the UK and in certain other countries © Oxford University Press 2015 The moral rights of the authors have been asserted First Edition published in 2015 Impression: 1 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, without the prior permission in writing of Oxford University Press, or as expressly permitted by law, by licence or under terms agreed with the appropriate reprographics rights organization. Enquiries concerning reproduction outside the scope of the above should be sent to the Rights Department, Oxford University Press, at the address above You must not circulate this work in any other form and you must impose this same condition on any acquirer Published in the United States of America by Oxford University Press 198 Madison Avenue, New York, NY 10016, United States of America British Library Cataloguing in Publication Data Data available Library of Congress Control Number: 2015933911 ISBN 978–0–19–966409–2 Printed in China by Asia Pacific Offset Ltd. Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct.
    [Show full text]
  • A Primer on Stroke Prevention Treatment: an Overview Based on AHA/ASA Guidelines
    A Primer on Stroke Prevention Treatment: An Overview Based on AHA/ASA Guidelines A Primer on Stroke Prevention Treatment: An Overview Based on AHA/ASA Guidelines, 1st Edition. Edited by Larry B. Goldstein © 2009 American Heart Association. ISBN: 978-1-405-18651-3 A Primer on Stroke Prevention Treatment: An Overview Based on AHA/ASA Guidelines Edited by Larry B. Goldstein Professor of Medicine Duke University Medical Center Durham, North Carolina USA A John Wiley & Sons, Ltd., Publication This edition fi rst published 2009, © 2009 American Heart Association American Heart Association National Center, 7272 Greenville Avenue, Dallas, TX 75231, USA For further information on the American Heart Association: www.americanheart.org Blackwell Publishing was acquired by John Wiley & Sons in February 2007. Blackwell’s publishing program has been merged with Wiley’s global Scientifi c, Technical and Medical business to form Wiley-Blackwell. Registered offi ce: John Wiley & Sons Ltd, The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, UK Editorial offi ces: 9600 Garsington Road, Oxford, OX4 2DQ, UK The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, UK 111 River Street, Hoboken, NJ 07030-5774, USA For details of our global editorial offi ces, for customer services and for information about how to apply for permission to reuse the copyright material in this book please see our website at www.wiley.com/wiley-blackwell The right of the author to be identifi ed as the author of this work has been asserted in accordance with the Copyright, Designs and Patents Act 1988. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by the UK Copyright, Designs and Patents Act 1988, without the prior permission of the publisher.
    [Show full text]
  • Effect of Alteplase on the CT Hyperdense Artery Sign and Outcome After Ischemic Stroke
    ARTICLES Effect of alteplase on the CT hyperdense artery sign and outcome after ischemic stroke Grant Mair, MBChB ABSTRACT Rüdiger von Kummer, Objective: To investigate whether the location and extent of the CT hyperdense artery sign (HAS) ProfDrmed at presentation affects response to IV alteplase in the randomized controlled Third International Zoe Morris, MBBS Stroke Trial (IST-3). Anders von Heijne, MD Methods: All prerandomization and follow-up (24–48 hours) CT brain scans in IST-3 were Nick Bradey, MBBS assessed for HAS presence, location, and extent by masked raters. We assessed whether HAS Lesley Cala, MD grew, persisted, shrank, or disappeared at follow-up, the association with 6-month functional André Peeters, MD outcome, and effect of alteplase. IST-3 is registered (ISRCTN25765518). Andrew J. Farrall, MD Alessandro Adami, MD Results: HAS presence (vs absence) independently predicted poor 6-month outcome (increased Gillian Potter, MD Oxford Handicap Scale [OHS]) on adjusted ordinal regression analysis (odds ratio [OR] 0.66, p , p 5 Geoff Cohen, MSc 0.001). Outcome was worse in patients with more (vs less) extensive HAS (OR 0.61, p 5 Peter A.G. Sandercock, 0.027) but not in proximal (vs distal) HAS ( 0.420). Increasing age was associated with more p 5 DM HAS growth at follow-up (OR 1.01, 0.013). Treatment with alteplase increased HAS shrink- p 5 Richard I. Lindley, MD age/disappearance at follow-up (OR 0.77, 0.006). There was no significant difference in HAS p 5 p 5 Joanna M. Wardlaw, MD shrinkage with alteplase in proximal (vs distal) or more (vs less) extensive HAS ( 0.516 and For the IST-3 0.580, respectively).
    [Show full text]
  • Computed Tomography in Acute Ischemic Stroke
    View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by RERO DOC Digital Library Neuroradiology (2010) 52:175–187 DOI 10.1007/s00234-009-0633-5 INVITED REVIEW Computed tomography in acute ischemic stroke Karl-Olof Lövblad & Alison E. Baird Received: 16 February 2009 /Accepted: 16 November 2009 /Published online: 2 December 2009 # Springer-Verlag 2009 Abstract Stroke remains the third most important cause of Introduction mortality in industrialized countries; this has prompted research for improvements in both diagnostic and thera- Acute stroke is an important cause of morbidity and peutic strategies for patients with signs of acute cerebral mortality in all industrialized nations. For a long time, it ischemia. Over the last decade, there has been a parallel in was considered a hopeless situation with at best the progress in techniques in both diagnostic and therapeutic prospect of lengthy rehabilitation periods for the affected options. While previously only used for excluding hemor- patients. However, due to an impressive investment in rhage, imaging now has the possibility to detect ischemia, energy during the decade of the brain in the 1990s, this vascular occlusion, as well as detect tissue at risk in one purely attentive attitude has now been overcome, and over setting. It should also allow to monitor treatment and the last decade, thrombolysis has become an established predict/exclude therapeutic complications. Parallel to standard of care [1–6]. This has been due to the advances in magnetic resonance imaging of stroke, com- simultaneous development of both new diagnostic and puted tomography has improved immensely over the last therapeutic strategies that have changed completely our decade due to the development of CT scanners that are vision of the disease.
    [Show full text]
  • Hemorrhagic Transformation of Ischemic Stroke
    Vascular Diseases and Therapeutics Review Article ISSN: 2399-7400 Hemorrhagic transformation of ischemic stroke János Marcell László1, Tibor Hortobágyi1,2* 1Division of Neuropathology, Institute of Pathology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary 2MTA-DE Cerebrovascular and Neurodegenerative Research Group, Debrecen, Hungary Abstract The better understanding of the diverse mechanisms leading to the hemorrhagic transformation of an ischemic stroke is the crucial point in the prevention of this altogether common phenomenon. The different individual risk factors include the anatomical variability of collateral blood supply, age, genetics, body weight, etiology of the occlusion, side of the occluded vessel, renal status, stroke severity, history of high serum glucose or hypertension and hypertension or hyperglycemia at the onset of the stroke, ferritin level, INR, antiplatelet usage or the platelet count etc. All these might contribute to the process of hemorrhagic transformation. These risk factors have been identified by retrospective epidemiological studies and are useful to identify patients who are at high risk for hemorrhagic conversion and help the decision between conservative, thrombolytic or more advanced treatments such as thrombectomy. The modulations of potential molecular targets participating in the process seem to be promising in animal models, but human trials are lacking the breakthrough success so far, both in extending the time frame of the thrombolysis and in replacing the recombinant tissue plasminogen activator (rtPA) as thrombolytic agent. So far, the careful preselection of patients eligible for thrombolytic therapy is the best way to prevent hemorrhagic transformation. The intensive research in the field revealing small but important molecular details are continuously contributing to the better understanding of hemorrhagic transformation with the intention of finding new agents that co-administrated to the rtPA or completely replacing that could decrease the risk of secondary bleeding.
    [Show full text]
  • Sree Chitra Tirunal Institute for Medical Sciences and Technology Thiruvananthapuram, Kerala
    SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECHNOLOGY THIRUVANANTHAPURAM, KERALA Risk Factors, Outcome and Predictors of Outcome in Young Patients with Ischemic Stroke Thesis submitted in partial fulfilment of the rules and regulations for DM Degree Examination of Sree Chitra Tirunal Institute for Medical Sciences and Technology By Dr Alok Mandliya DM Neurology Resident Month and Year of Submission: October 2013 Department of Neurology SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECHNOLOGY THIRUVANANTHAPURAM 2011-2013 i INTRODUCTION 1 Introduction The incidence of stroke rises exponentially with age and is therefore low in young adults.1 But, ischaemic stroke in young adults is a common cause of admission to stroke units and referral to neurology departments or tertiary hospitals. 2,3 1 While a specific definition of ―young stroke‖ is lacking, the vast majority of studies consider ―young stroke‖ to pertain to individuals 15-45 years of age. Traditional risk factors for stroke such as hypertension and diabetes are not very frequent in young adults; however, some other permanent or transient risk factors such as smoking, use of oral contraceptives, migraine, trauma, use of illicit drugs, and pregnancy or puerperium have a more important role in this age group than in older adults. The main clinical challenge in management of a young adult with acute stroke is the identification of its cause. Although large extracranial and intracranial atheroma, small-vessel disease, and atrial fibrillation 2,3 have a major role in cases of stroke in older adults, these disorders are much less frequent in young adults. Though a change in life style pattern led to epidemic of traditional risk factors at younger population also.
    [Show full text]
  • Complete Issue (PDF)
    APRIL 2020 AJNR VOLUME 41 PP 551–736 APRIL 2020 THE JOURNAL OF DIAGNOSTIC AND VOLUME 41 INTERVENTIONAL NEURORADIOLOGY NUMBER 4 WWW.AJNR.ORG MR thermometry in cerebrovascular disease Hippocampal sclerosis detection with NeuroQuant CTA diagnostic errors in evaluation of LVO Enhancement of vestibular perilymph in Menière disease Official Journal ASNR • ASFNR • ASHNR • ASPNR • ASSR FLOW DIVERSION. SIMPLIFIED. FRED™ Flow Re-direction Endoluminal Device The Flow Re-Direction Endoluminal Device (FRED) System is indicated for use in the internal carotid artery from the petrous segment to the terminus for the endovascular treatment of adult patients (22 years of age or older) with wide-necked (neck width ≥ 4 mm or dome-to-neck ratio < 2) saccular or fusiform intracranial aneurysms arising from a parent vessel with a diameter ≥ 2.0 mm and ≤ 5.0 mm. Use of the FRED System is contraindicated under these circumstances: Patients in whom anticoagulant, anti-platelet therapy, or thrombolytic drugs are contraindicated. Patients with known hypersensitivity to metal such as nickel-titanium and metal jewelry. Patients with anatomy that does not permit passage or deployment of the FRED System. Patients with an active bacterial infection. Patients with a pre-existing stent in place at the target aneurysm. Patients in whom the parent vessel size does not fall within the indicated range. Patients who have not received dual anti-platelet agents prior to the procedure. For complete indications, contraindications, potential complications, warnings, precautions, and instructions, see instructions for use (IFU provided in the device). HEADWAY Microcatheter Indications for Use: The HEADWAY Microcatheter is intended for general intravascular use, including the peripheral, coronary and neurovasculature for the infusion of diagnostic agents, such as contrast media, and therapeutic agents, such as occlusion coils.
    [Show full text]
  • In Ischaemic Stroke
    Cheripelli, Bharath kumar (2020) Acute ischaemic stroke-multimodal imaging and stroke outcomes. MD thesis. http://theses.gla.ac.uk/81736/ Copyright and moral rights for this work are retained by the author A copy can be downloaded for personal non-commercial research or study, without prior permission or charge This work cannot be reproduced or quoted extensively from without first obtaining permission in writing from the author The content must not be changed in any way or sold commercially in any format or medium without the formal permission of the author When referring to this work, full bibliographic details including the author, title, awarding institution and date of the thesis must be given Enlighten: Theses https://theses.gla.ac.uk/ [email protected] 1 Acute Ischaemic Stroke- Multi modal Imaging and Stroke outcomes Dr Bharathkumar Cheripelli MBBS, MRCP, CCT (Neurology) A thesis which fulfils the requirements of the University of Glasgow for the degree of Doctorate of Medicine Institute of Neuroscience and Psychology University of Glasgow October 2019 2 Abstract Introduction Acute stroke Imaging plays a crucial role in understanding the cerebral tissue states and multimodal imaging with perfusion, collaterals and vessel occlusion provides more information on tissue dynamics in individual patient which can be useful for tailored treatments and prognosis. Perfusion parameters and their validation are important in achieving clinical practicality. A novel tissue parameter, Capillary transit time heterogeneity has been suggested to identify micro vascular flow patterns. The clinical utility of this is not yet established. Stroke outcome is dependant not only on the imaging parameters but also on patient demographics, co morbidities and probably on complex socio-economic and other unidentified patient factors.
    [Show full text]
  • Complete Issue (PDF)
    MAY 2018 AJNR VOLUME 39 • PP 797–992 MAY 2018 THE JOURNAL OF DIAGNOSTIC AND VOLUME 39 INTERVENTIONAL NEURORADIOLOGY NUMBER 5 WWW.AJNR.ORG Current status of vertebroplasty and kyphoplasty Treatment of giant aneurysms with Tubridge flow diverter Ear malformations in 22q11.2 deletion syndrome Official Journal ASNR • ASFNR • ASHNR • ASPNR • ASSR Low-profile Visualized Intraluminal Support Stent Deployment. Refined. Braided Coil Assist Stents with High Neck Coverage, Excellent Visibility and Improved Conformability* Aneurysm Therapy Solutions For more information or a product demonstration, contact your local MicroVention representative: MicroVention Worldwide Innovation Center PH +1.714.247.8000 35 Enterprise *Humanitarian Device: Authorized by Federal Law for use with bare platinum Aliso Viejo, CA 92656 USA embolic coils for the treatment of unruptured, wide neck (neck ≥ 4 mm or dome to neck ratio < 2), intracranial, saccular aneurysms arising from a parent MicroVention UK Limited PH +44 (0) 191 258 6777 vessel with a diameter ≥ 2.5 mm and ≤ 4.5 mm. The effectiveness of this device MicroVention Europe, S.A.R.L. PH +33 (1) 39 21 77 46 for this use has not been demonstrated. MicroVention Deutschland GmbH PH +49 211 210 798-0 microvention.com MICROVENTION and LVIS are registered trademarks of MicroVention, Inc. • Refer to Instructions for Use, contraindications and warnings for additional information. Federal (USA) law restricts this device for sale by or on the order of a physician. ©2018 MicroVention, Inc. Jan. 2018 Now you have 24 hours to make a lifetime of difference in stroke patients like Nora The Trevo Retriever is the only device cleared to reduce disability in stroke patients up to 24 hours from time last seen well.
    [Show full text]