Maria Khan, Matthew Epperson, Disconnetted

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Maria Khan, Matthew Epperson, Disconnetted positivelyaware.com MAY+JUNE 2012 TWo EPIDEMICS IncarceratIon and HIV How the criminal justice system can play an effective role in the treatment and prevention of HIV ThE benefiTs of opT-out tesTiNg risk fAcTors for women coNfErencE Update: croi B:16.5 in T:16 in S:15 in www.egrifta.com YOU’VE WORKED TO CONTROL YOUR HIV. NOW, TIME TO WORK ON YOUR FILE NAME 0053_EGR_AD_SPD_ HIV-RELATED EXCESS BELLY FAT. PA_May_August_ In two separate clinical trials of HIV-infected people with lipodystrophy, each lasting 6 months, EGRIFTA® (tesamorelin M3.inddDATE 03.30.12 for injection) reduced HIV-related excess belly fat by an average of 18% in the rst trial, and 14% in the second trial. CLIENT This reduction in excess belly fat resulted in an approximate 1-inch reduction in waist size. Individual results may vary. On ® Egrifta average, patients on EGRIFTA did not lose weight. PART # Like HIV, HIV-related excess belly fat is a chronic condition. In clinical studies: 120127-102148 • People who used EGRIFTA® continuously for 1 year maintained their results over this time period DESCRIPTION • People who stopped taking EGRIFTA® after 6 months had their HIV-related excess belly fat come back EGRIFTA® is believed to work with your own body to produce natural growth hormone to reduce your excess belly fat. Print Ad Positively Aware - Spread SPECS Indication: EGRIFTA® is a daily injectable prescription medicine to reduce the excess abdominal fat in HIV-infected patients with lipodystrophy. Trim: 16 x 10.5” Limitations of use: Bleed: 16.5 x 11” • The impact and safety of EGRIFTA® on cardiovascular health has not been studied Safety: 15 x 9.5” • EGRIFTA® is not indicated for weight-loss management Gutter: 1” • It’s not known whether taking EGRIFTA® helps improve compliance with antiretroviral medications Colors: 4C, CMYK • EGRIFTA® is not recommended to be used in children COLOR INFO Important Risk Information • Injection-site reactions, such as redness, itching, pain, irritation, T:10.5 in T:10.5 S:9.5 in Do not use EGRIFTA® if you: bleeding, rash, and swelling. Change (rotate) your injection site to help B:11 in • Have pituitary gland tumor, pituitary gland surgery, or other problems lower your risk for injection-site reactions related to your pituitary gland ® • Have active cancer (either newly diagnosed or recurrent) or are The most common side effects of EGRIFTA include: receiving treatment for cancer • joint pain • numbness and pricking MECH. BUILT TO • Are allergic to tesamorelin or any of the ingredients in EGRIFTA®, • pain in legs and arms • nausea • swelling in your legs • vomiting 100% including mannitol or sterile water • Are pregnant or become pregnant • muscle soreness • rash PRINTED AT • tingling • itching Before using EGRIFTA , ® tell your healthcare provider if you: 100% ® • Have or have had cancer EGRIFTA will NOT cure HIV or lower your chance of passing HIV to others. • Have diabetes You are encouraged to report negative side effects of prescription • Are breastfeeding or plan to breastfeed drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. • Have kidney or liver problems • Have any other medical condition Please see Consumer Brief Summary of EGRIFTA® on following page. • Take prescription or non-prescription medicines, vitamins, or Ask your healthcare provider if EGRIFTA®, the rst herbal supplements and only FDA-approved medicine for HIV-related EGRIFTA® may cause serious side effects, including: excess belly fat, may be right for you. For more • Serious allergic reaction. Stop using EGRIFTA® and get emergency information, visit www.egrifta.com or call the help right away if you have any of the following symptoms: rash over AXIS Center at 1-877-714-AXIS (2947). your body, hives, swelling of your face or throat, shortness of breath or trouble breathing, fast heartbeat, feeling of faintness or fainting • Swelling (fl uid retention). EGRIFTA® can cause swelling in some parts of your body. Call your healthcare provider if you have an increase in joint pain, or pain or numbness in your hands or wrist (carpal tunnel syndrome) • Increase in glucose (blood sugar) intolerance and diabetes Actual patient living with HIV since 2000 120127-102148 2/12 B:16.5 in T:16 in S:15 in www.egrifta.com YOU’VE WORKED TO CONTROL YOUR HIV. NOW, TIME TO WORK ON YOUR FILE NAME 0053_EGR_AD_SPD_ HIV-RELATED EXCESS BELLY FAT. PA_May_August_ In two separate clinical trials of HIV-infected people with lipodystrophy, each lasting 6 months, EGRIFTA® (tesamorelin M3.inddDATE 03.30.12 for injection) reduced HIV-related excess belly fat by an average of 18% in the rst trial, and 14% in the second trial. CLIENT This reduction in excess belly fat resulted in an approximate 1-inch reduction in waist size. Individual results may vary. On ® Egrifta average, patients on EGRIFTA did not lose weight. PART # Like HIV, HIV-related excess belly fat is a chronic condition. In clinical studies: 120127-102148 • People who used EGRIFTA® continuously for 1 year maintained their results over this time period DESCRIPTION • People who stopped taking EGRIFTA® after 6 months had their HIV-related excess belly fat come back EGRIFTA® is believed to work with your own body to produce natural growth hormone to reduce your excess belly fat. Print Ad Positively Aware - Spread SPECS Indication: EGRIFTA® is a daily injectable prescription medicine to reduce the excess abdominal fat in HIV-infected patients with lipodystrophy. Trim: 16 x 10.5” Limitations of use: Bleed: 16.5 x 11” • The impact and safety of EGRIFTA® on cardiovascular health has not been studied Safety: 15 x 9.5” • EGRIFTA® is not indicated for weight-loss management Gutter: 1” • It’s not known whether taking EGRIFTA® helps improve compliance with antiretroviral medications Colors: 4C, CMYK • EGRIFTA® is not recommended to be used in children COLOR INFO Important Risk Information • Injection-site reactions, such as redness, itching, pain, irritation, T:10.5 in T:10.5 S:9.5 in Do not use EGRIFTA® if you: bleeding, rash, and swelling. Change (rotate) your injection site to help B:11 in • Have pituitary gland tumor, pituitary gland surgery, or other problems lower your risk for injection-site reactions related to your pituitary gland ® • Have active cancer (either newly diagnosed or recurrent) or are The most common side effects of EGRIFTA include: receiving treatment for cancer • joint pain • numbness and pricking MECH. BUILT TO • Are allergic to tesamorelin or any of the ingredients in EGRIFTA®, • pain in legs and arms • nausea • swelling in your legs • vomiting 100% including mannitol or sterile water • Are pregnant or become pregnant • muscle soreness • rash PRINTED AT • tingling • itching Before using EGRIFTA , ® tell your healthcare provider if you: 100% ® • Have or have had cancer EGRIFTA will NOT cure HIV or lower your chance of passing HIV to others. • Have diabetes You are encouraged to report negative side effects of prescription • Are breastfeeding or plan to breastfeed drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. • Have kidney or liver problems • Have any other medical condition Please see Consumer Brief Summary of EGRIFTA® on following page. • Take prescription or non-prescription medicines, vitamins, or Ask your healthcare provider if EGRIFTA®, the rst herbal supplements and only FDA-approved medicine for HIV-related EGRIFTA® may cause serious side effects, including: excess belly fat, may be right for you. For more • Serious allergic reaction. Stop using EGRIFTA® and get emergency information, visit www.egrifta.com or call the help right away if you have any of the following symptoms: rash over AXIS Center at 1-877-714-AXIS (2947). your body, hives, swelling of your face or throat, shortness of breath or trouble breathing, fast heartbeat, feeling of faintness or fainting • Swelling (fl uid retention). EGRIFTA® can cause swelling in some parts of your body. Call your healthcare provider if you have an increase in joint pain, or pain or numbness in your hands or wrist (carpal tunnel syndrome) • Increase in glucose (blood sugar) intolerance and diabetes Actual patient living with HIV since 2000 120127-102148 2/12 T:8 in S:7 in Consumer Brief Summary for EGRIFTA® (tesamorelin for injection) EGRIFTA® (eh-GRIF-tuh) – hives (tesamorelin for injection) for subcutaneous use – swelling of your face or throat – shortness of breath or trouble breathing Read the Patient Information that comes with EGRIFTA® before you start to take it – fast heartbeat and each time you get a refill. There may be new information. This leaflet does not take – feeling of faintness or fainting FILE NAME the place of talking to your healthcare provider about your medical condition or • Swelling (fluid retention).EGRIFTA ® can cause swelling in some parts of your body. 0053_EGR_AD_PI_PA_ your treatment. Call your healthcare provider if you have an increase in joint pain, or pain or ® May_August_M1.indd What is EGRIFTA ? numbness in your hands or wrist (carpal tunnel syndrome) DATE • EGRIFTA® is an injectable prescription medicine to reduce the excess in abdominal 03.27.12 fat in HIV-infected patients with lipodystrophy. EGRIFTA® contains a growth • Increase in glucose (blood sugar) intolerance and diabetes. Your healthcare provider CLIENT hormone-releasing factor (GRF) will measure your blood sugar periodically ® EMD Serono • The impact and safety of EGRIFTA on cardiovascular health has not been studied • Injection-site reactions. Change (rotate) your injection site to help lower your risk for • EGRIFTA ® is not indicated for weight-loss management PART # injection-site reactions. Call your healthcare provider for medical advice if you have • I t is not known whether taking EGRIFTA® helps improve compliance with the following symptoms around the area of the injection site: antiretroviral medications – redness – bleeding ® ® DESCRIPTION • It is not known if EGRIFTA is safe and effective in children.
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