Positive About HIV—An Immunological Education Project in South Africa

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Positive About HIV—An Immunological Education Project in South Africa COMMENTARY South Africa is in the throes of an AIDS epidemic compounded by tuberculosis. Nevertheless, responses to the recent launch of a colorful book promoting adolescent knowledge of HIV immunopathogenesis provide grounds for cautious optimism that education can induce a form of “social vaccination” in South Africa and elsewhere. Positive about HIV—an immunological education project in South Africa Siamon Gordon Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK. ([email protected]) “Siyathemba” (“we hope” in Zulu) is inscribed on the wall of the A need to promote prevention newly built Africa Centre in Mtubatuba, a project of the Wellcome With hindsight, it is clear that the SA epidemic followed other coun- Trust, South African Medical Research Council (MRC) and the tries outside Africa as well as further north in Africa. A major University of Natal, South Africa (SA). These words contrast with opportunity to limit the spread of HIV in SA was lost during the last the almost universal gloom currently attached to the subject. years of the apartheid regime (even if it had not been distracted by its Widespread awareness of the own survival, the motives of a white explosive AIDS-tuberculosis epi- government campaign to limit sexual demic and its impact on all aspects transmission among Africans would http://www.nature.com/natureimmunology of South African society has gener- have been regarded with suspicion). ated a growing response by South After Nelson Mandela became the African health scientists, educators first democratically elected President and governmental as well as non- in 1994, his power-sharing govern- governmental (NGO) agencies. ment was concerned with avoidance Evidence for this more balanced of a civil war between Inkatha-affili- perception was obtained by a small ated Zulus, the Xhosa-based ANC group of immunologists and their and the remaining diehard partners on a visit to several cen- Afrikaners. Nation-building took pri- ters in SA to launch the children’s ority over AIDS prevention, apart book Staying Alive – Fighting from misdirected efforts to find HIV/AIDS1. unique local solutions, such as a I became involved in this project home-grown specious remedy © Group 2002 Nature Publishing in 1999, in Cape Town, SA, when I known as Virodene. Thabo Mbeki, was struck by the still insufficient already running the daily affairs of awareness of the scale of this threat the country while Mandela focused to the continent, which carries the on reconciliation and diplomacy, and major burden of AIDS worldwide. Students at Siyulalame School, KwazuluNatal, making a presentation about AIDS to successive health ministers contin- My colleagues in this effort were their classmates. ued to obstruct a science-based Fran Balkwill, a tumor immunobio- response to the intensifying AIDS logist from London and Mic Rolph, emergency. The South African a designer-illustrator—who, together, had produced half-a-million sci- MRC2, the judiciary, regional governments and NGO pressure groups ence books for children—and John Inglis, a Scottish-born immunolo- such as the Treatment Action Campaign (TAC) have, however, done a gist who was the founding editor of Immunology Today and is now great deal to document its impact and to promote public awareness and the executive editor of Cold Spring Harbor Laboratory Press, New so, at the moment, the tide is turning. York. The team was completed by Linzi Rabinowitz, a South African Inevitably, attitudes have become polarized, as if prevention strate- social worker, Lyndall Gordon, an expatriate biographer, and Tony gies, anti-retroviral drug costs, primary health care and counseling are Inglis, a British-born, American-educated liberal arts student. This separate issues. Although it is impossible to extrapolate from nonuni- commentary is based on our communal experience as well as my own form local statistics and the public health system does not require noti- reactions. fication and widespread testing, there is no doubt that HIV infection The text of the book, aimed at teenagers, provides up-to-date science poses a massive threat to health management (many patients undergo- accompanied by accessible illustrations from which self-protective ing hospital admission are coincidentally HIV+) and is responsible for actions can follow. Twenty-thousand copies of the 32-page book were the spread of tuberculosis. More generally, it exerts a crippling effect distributed free in a pilot study to evaluate its impact and suitability. on the economy, educational system, prison population and army. Future plans include greatly expanded distribution in Africa and else- where. The reception by children and adults alike was overwhelmingly Writing the book positive, and the visit provided an opportunity to assess the present The intention was to provide an up-to-date scientific explanation of social response to the still-expanding pandemic. the relationship between HIV and AIDS and the immunologic basis www.nature.com/natureimmunology • december 2002 • volume 3 no 12 • nature immunology 1115 COMMENTARY for its pathogenesis. We opted for an English text, using simple lan- Gugulethu and Kayelitsha Townships. Five HIV-infected women guage and phonetic spellings of scientific terms. Possible therapy and explained a “memory box” project, in which people record their life- vaccination were placed in perspective, given the reality in SA at the stories for their families, emphasizing living with HIV rather than time the book was written. The disease was treated in the context of leaving a post-mortem legacy. human infectious diseases and is explicit about transmission. The At a public gathering in Cape Town, Kader Asmal, the Minister of book was designed to be attractive, even humorous, while not shirk- Education, coined the term “social vaccination” through education ing the seriousness of the issues discussed. It does not moralize but and the eloquence of an HIV+ community activist, Lungi Mazibuko, advises sexual abstinence and permanent, loving relationships. The electrified the audience. One of the most impressive features of our hopeful fact is made clear that HIV-infected people can live healthy, visit was the leadership displayed by HIV+ women and men, ener- productive lives and that they deserve care and physical affection gized by knowledge of the risk to themselves, their families and the without stigma. community at large. The content emerged from a Linzi distributed questionnaires series of consultations, starting to obtain more information about with a visit in 2001 by Fran and the suitability of the book and its Mic to SA (Mtubatuba and impact—many requests for copies Gauteng), where—accompanied by followed, from teachers, doctors Fran’s teenage son, Barnaby—they and parents. Suggestions included met children and teachers in a version for younger children schools, squatter camps and town- before sexual attitudes form; a ships. Children were invited to “granny” version for older care- express their concerns, which were givers to AIDS orphans; additional surprisingly uniform whether they teachers’ aides and translations of http://www.nature.com/natureimmunology came from urban or rural schools, the book into Zulu, Xhosa, Sesotho and these were answered by the and Afrikaans. Perhaps most sur- text. Other collaborative offerings prising was the frank discussion took the form of drawings included and openness of teachers and in the book, in particular, drawings church members. of a patient before and after he Other members of the team developed AIDS by Nelson returned to Europe and the USA, Makhonya from the Zevenfontein Self-portrait of HIV+ woman, art project at University of Cape Town. but my wife and I stayed on to squatter camp. meet educators, artists and the media. We were particularly pleased to compare notes with Takelani Reaching the children (“Rejoice”) Sesame, a South African version of Sesame Street that Our small party of seven set out with some uncertainty. How would features an HIV+ muppet in their television broadcasts (it is not only the book be viewed? Would it be understood, was it too explicit and the South African government that has difficulty with spreading the © Group 2002 Nature Publishing was it appropriate for 11–16-year-old readers? Would we be received message—US congressmen recently objected to such a use of public as well intentioned but ignorant outsiders? Was the message too late funding). and had the book already been superseded by other educational mate- rials? As it turned out, the book was well received and timely. Mic Grounds for optimism and Fran wished to return to the same schools they had originally vis- What, then, is the basis for my earlier optimism, even in the face of ited in preparing the book and present children with books in which this still growing crisis? The situation in SA has changed dramatically their own contributions and illustrations had been published. Their over the past few years, as if a slumbering giant has begun to stir. return was greeted with surprised pleasure. Mic’s state-of-the-art People from all sectors in society appreciate the nature of the crisis, video camera and blown-up photographs of many of the children are eager to learn more about the specifics and want to do something evoked exclamations of delight. A return visit was made to about it, despite and perhaps stimulated by the widely publicized lack Zevenfontein (an “informal” settlement cheek-by-jowl with luxurious of consistent
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