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Curative Pelvic Exenteration for Recurrent Cervical Carcinoma in the Era of Concurrent Chemotherapy and Radiation Therapy
Available online at www.sciencedirect.com ScienceDirect EJSO xx (2015) 1e11 www.ejso.com Review Curative pelvic exenteration for recurrent cervical carcinoma in the era of concurrent chemotherapy and radiation therapy. A systematic review H. Sardain a,b, V. Lavoue a,b,c,*, M. Redpath d, N. Bertheuil b,e, F. Foucher a,J.Lev^eque a,b,c a CHU de Rennes, Gynecology Department, Tertiary Surgery Center, Teaching Hospital of Rennes, Hopital^ Sud, 16, Bd de Bulgarie, 35000 Rennes, France b Universite de Rennes, Faculty of Medicine, 2 Henry Guilloux, 35000 Rennes, France c INSERM, ER440, Oncogenesis, Stress and Signaling (OSS), Rennes, France d McGill University, Department of Pathology, Jewish General Hospital, Cote^ Sainte Catherine, Montreal, QC, Canada e CHU de Rennes, Department of Plastic, Reconstructive and Aesthetic Surgery, Tertiary Surgery Center, Teaching Hospital of Rennes, Hopital^ Sud, 16, Bd de Bulgarie, 35000 Rennes, France Accepted 26 March 2015 Available online --- Abstract Objective: Pelvic exenteration requires complete resection of the tumor with negative margins to be considered a curative surgery. The pur- pose of this review is to assess the optimal preoperative evaluation and surgical approach in patients with recurrent cervical cancer to in- crease the chances of achieving a curative surgery with decreased morbidity and mortality in the era of concurrent chemoradiotherapy. Methods: Review of English publications pertaining to cervical cancer within the last 25 years were included using PubMed and Cochrane Library searches. Results: Modern imaging (MRI and PET-CT) does not accurately identify local extension of microscopic disease and is inadequate for pre- operative planning of extent of resection. -
Product Catalog Stainless Steel Vaginal Specula
PRODUCT CATALOG STAINLESS STEEL VAGINAL SPECULA Graves Speculum Product No. Description LTL-GS300 Graves Speculum, Small 3” x .75” LTL-GS400 Graves Speculum, Medium 4” x 1.5” LTL-GS450 Graves Speculum, Large 4.50” x 1.5” LTL-GS700 Graves Speculum, XL 7” x 1.5” Pederson Speculum Product No. Description LTL-PS305 Pederson Speculum, Virginal 3” x .5” LTL-PS300 Pederson Speculum, Small 3” x 1” LTL-PS400 Pederson Speculum, Medium 4” x 1” LTL-PS450 Pederson Speculum, Large 4.5” x 1” LTL-PS455 Pederson Speculum, Extra Narrow 4.5” x .5” LTL-PS700 Pederson Speculum, XL 7” x 1” Open Sided Speculum Product No. Description LTL-WGR400 Weisman-Graves Speculum, Medium, Right Open 4” x 1.5” LTL-WGR450 Weisman-Graves Speculum, Large, Right Open 4.5” x 1.5” LTL-WGL400 Weisman-Graves Speculum, Medium, Left Open 4” x 1.5” LTL-WGL450 Weisman-Graves Speculum, Large, Left Open 4.5” x 1.5” LTL-WPR400 Weisman-Pederson Speculum, Medium, Right Open 4” x 1” LTL-WPR450 Weisman-Pederson Speculum, Large, Right Open 4.5” x 1” LTL-WPL400 Weisman-Pederson Speculum, Medium, Left Open 4” x 1” LTL-WPL450 Weisman-Prderspm Speculum, Large, Left Open 4.5” x 1” *We also offer wide view (4cm) and full view (7cm) openings. 1 | TOLL FREE 1 [800] 910-8303 FAX 1 [805] 579-9415 WWW.LTLMEDICAL.NET BIOPSY PUNCHES Standard Style Rotating Style Tischler [Morgan] 7mm x 3mm Baby Tischler 4mm x 2mm Tischler Kevorkian 9.5mm x 3mm Product No. Description Product No. Description Product No. -
Partial Nephrectomy for Renal Cancer: Part I
REVIEW ARTICLE Partial nephrectomy for renal cancer: Part I BJUIBJU INTERNATIONAL Paul Russo Department of Surgery, Urology Service, and Weill Medical College, Cornell University, Memorial Sloan Kettering Cancer Center, New York, NY, USA INTRODUCTION The Problem of Kidney Cancer Kidney Cancer Is The Third Most Common Genitourinary Tumour With 57 760 New Cases And 12 980 Deaths Expected In 2009 [1]. There Are Currently Two Distinct Groups Of Patients With Kidney Cancer. The First Consists Of The Symptomatic, Large, Locally Advanced Tumours Often Presenting With Regional Adenopathy, Adrenal Invasion, And Extension Into The Renal Vein Or Inferior Vena Cava. Despite Radical Nephrectomy (Rn) In Conjunction With Regional Lymphadenectomy And Adrenalectomy, Progression To Distant Metastasis And Death From Disease Occurs In ≈30% Of These Patients. For Patients Presenting With Isolated Metastatic Disease, Metastasectomy In Carefully Selected Patients Has Been Associated With Long-term Survival [2]. For Patients With Diffuse Metastatic Disease And An Acceptable Performance Status, Cytoreductive Nephrectomy Might Add Several Additional Months Of Survival, As Opposed To Cytokine Therapy Alone, And Prepare Patients For Integrated Treatment, Now In Neoadjuvant And Adjuvant Clinical Trials, With The New Multitargeted Tyrosine Kinase Inhibitors (Sunitinib, Sorafenib) And Mtor Inhibitors (Temsirolimus, Everolimus) [3,4]. The second groups of patients with kidney overall survival. The explanation for this cancer are those with small renal tumours observation is not clear and could indicate (median tumour size <4 cm, T1a), often that aggressive surgical treatment of small incidentally discovered in asymptomatic renal masses in patients not in imminent patients during danger did not counterbalance a population imaging for of patients with increasingly virulent larger nonspecific abdominal tumours. -
What a Difference a Delay Makes! CT Urogram: a Pictorial Essay
Abdominal Radiology (2019) 44:3919–3934 https://doi.org/10.1007/s00261-019-02086-0 SPECIAL SECTION : UROTHELIAL DISEASE What a diference a delay makes! CT urogram: a pictorial essay Abraham Noorbakhsh1 · Lejla Aganovic1,2 · Noushin Vahdat1,2 · Soudabeh Fazeli1 · Romy Chung1 · Fiona Cassidy1,2 Published online: 18 June 2019 © This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2019 Abstract Purpose The aim of this pictorial essay is to demonstrate several cases where the diagnosis would have been difcult or impossible without the excretory phase image of CT urography. Methods A brief discussion of CT urography technique and dose reduction is followed by several cases illustrating the utility of CT urography. Results CT urography has become the primary imaging modality for evaluation of hematuria, as well as in the staging and surveillance of urinary tract malignancies. CT urography includes a non-contrast phase and contrast-enhanced nephrographic and excretory (delayed) phases. While the three phases add to the diagnostic ability of CT urography, it also adds potential patient radiation dose. Several techniques including automatic exposure control, iterative reconstruction algorithms, higher noise tolerance, and split-bolus have been successfully used to mitigate dose. The excretory phase is timed such that the excreted contrast opacifes the urinary collecting system and allows for greater detection of flling defects or other abnormali- ties. Sixteen cases illustrating the utility of excretory phase imaging are reviewed. Conclusions Excretory phase imaging of CT urography can be an essential tool for detecting and appropriately characterizing urinary tract malignancies, renal papillary and medullary abnormalities, CT radiolucent stones, congenital abnormalities, certain chronic infammatory conditions, and perinephric collections. -
Urology Services in the ASC
Urology Services in the ASC Brad D. Lerner, MD, FACS, CASC Medical Director Summit ASC President of Chesapeake Urology Associates Chief of Urology Union Memorial Hospital Urologic Consultant NFL Baltimore Ravens Learning Objectives: Describe the numerous basic and advanced urology cases/lines of service that can be provided in an ASC setting Discuss various opportunities regarding clinical, operational and financial aspects of urology lines of service in an ASC setting Why Offer Urology Services in Your ASC? Majority of urologic surgical services are already outpatient Many urologic procedures are high volume, short duration and low cost Increasing emphasis on movement of site of service for surgical cases from hospitals and insurance carriers to ASCs There are still some case types where patients are traditionally admitted or placed in extended recovery status that can be converted to strictly outpatient status and would be suitable for an ASC Potential core of fee-for-service case types (microsurgery, aesthetics, prosthetics, etc.) Increasing Population of Those Aged 65 and Over As of 2018, it was estimated that there were 51 million persons aged 65 and over (15.63% of total population) By 2030, it is expected that there will be 72.1 million persons aged 65 and over National ASC Statistics - 2017 Urology cases represented 6% of total case mix for ASCs Urology cases were 4th in median net revenue per case (approximately $2,400) – behind Orthopedics, ENT and Podiatry Urology comprised 3% of single specialty ASCs (5th behind -
Pelvic Exenteration for the Management of Pelvic Malignancies
Chapter 7 Pelvic Exenteration for the Management of Pelvic Malignancies Daniel Paramythiotis, Konstantinia Kofina and Antonios Michalopoulos Additional information is available at the end of the chapter http://dx.doi.org/10.5772/61083 Abstract Pelvic exenteration is a surgical procedure first described by Brunschwig in 1948 as a curative or palliative treatment for pelvic and perineal tumors. It is actually a radical operation, involving en bloc resection of pelvic organs, including reproductive structures, bladder, and rectosigmoid. In patients with recurrent cervical and vaginal malignancy, it is associated with a 5-year survival of more than 50%. In spite of advances in surgical management, consequences such as stomas, are still frequently unavoidable for radical tumor excision. Most candidates for this procedure have been diagnosed with recurrent cervical cancer that has previously been treated with surgery and radiation, or radiation alone. Complications of pelvic exenteration are more severe than those of standard resection of a colorectal carcinoma, so it is not commonly performed, including wound infection, wound dehiscence (also described as burst abdomen) the creation of fistulae (perineal-fecal, uretero-vaginal, between conduit and perineal wound), urinary tract infections, perineal hernias and intestinal obstruction. Patients need to be carefully selected and counseled about risks and long-term issues related to the surgery. A comprehensive evaluation is required in order to exclude unresectable or metastatic disease. Evolution of the technique through laparoscopy and minimally invasive surgery may result in a reduction of morbidity and mortality. Keywords: Pelvic exenteration, gynecologic cancer 1. Introduction Pelvic exenteration was first described by Brunschwig and his colleagues of New York’s Memorial Hospital in 1948 [1] and was initially performed as a palliative surgical intervention © 2015 The Author(s). -
Native Kidney Biopsy
Mohammed E, et al., J Nephrol Renal Ther 2020, 6: 034 DOI: 10.24966/NRT-7313/100034 HSOA Journal of Nephrology & Renal Therapy Review Article Native Kidney Biopsy: An Introduction The burden of non communicable diseases has been a worldwide Update and Best Practice public health challenge, as chronic diseases compose 61% of global deaths and 49% of the global burden of diseases. Currently, many Evidence countries are encountering a fast transformation in the disease pro- file from first generation diseases such as infectious diseases to the encumbrance of non communicable diseases. In addition, Chronic Ehab Mohammed1, Issa Al Salmi1 *, Shilpa Ramaiah1 and Suad Hannawi2 Kidney Disease (CKD) is increasingly recognized as a global public health challenge as 10% of the global population is affected [1,2]. 1Nephrologist, The Renal Medicine Department, The Royal Hospital, Muscat, Oman The scarcity of well-trained renal pathologists, even in high-in- come countries, is a major obstacle to use of biopsy samples. The ISN 2Medicine Department, Ministry of Health and Prevention, Dubai, UAE is working worldwide to enhance development of local renal patholo- gy expertise. Levin et al stated that analysis of kidney biopsy samples can be used to stratify CKD into distinct subgroups of diseases based Abstract on specific histological patterns, when combined with the clinical pre- sentation [3]. Diabetes mellitus and hypertensive nephropathy are the Objectives: To Provide up-to-date guidelines for medical and nurs- commonly identified causes of End-Stage Kidney Disease (ESKD). ing staffs on the pre, during, and post care of a patient undergoing a Also, many patients with glomerulonephritis, systemic lupus erythe- percutaneous-kidney-biopsy-PKB. -
Guidelines on Paediatric Urology S
Guidelines on Paediatric Urology S. Tekgül, H. Riedmiller, E. Gerharz, P. Hoebeke, R. Kocvara, R. Nijman, Chr. Radmayr, R. Stein European Society for Paediatric Urology © European Association of Urology 2011 TABLE OF CONTENTS PAGE 1. INTRODUCTION 6 1.1 Reference 6 2. PHIMOSIS 6 2.1 Background 6 2.2 Diagnosis 6 2.3 Treatment 7 2.4 References 7 3. CRYPTORCHIDISM 8 3.1 Background 8 3.2 Diagnosis 8 3.3 Treatment 9 3.3.1 Medical therapy 9 3.3.2 Surgery 9 3.4 Prognosis 9 3.5 Recommendations for crytorchidism 10 3.6 References 10 4. HYDROCELE 11 4.1 Background 11 4.2 Diagnosis 11 4.3 Treatment 11 4.4 References 11 5. ACUTE SCROTUM IN CHILDREN 12 5.1 Background 12 5.2 Diagnosis 12 5.3 Treatment 13 5.3.1 Epididymitis 13 5.3.2 Testicular torsion 13 5.3.3 Surgical treatment 13 5.4 Prognosis 13 5.4.1 Fertility 13 5.4.2 Subfertility 13 5.4.3 Androgen levels 14 5.4.4 Testicular cancer 14 5.4.5 Nitric oxide 14 5.5 Perinatal torsion 14 5.6 References 14 6. Hypospadias 17 6.1 Background 17 6.1.1 Risk factors 17 6.2 Diagnosis 18 6.3 Treatment 18 6.3.1 Age at surgery 18 6.3.2 Penile curvature 18 6.3.3 Preservation of the well-vascularised urethral plate 19 6.3.4 Re-do hypospadias repairs 19 6.3.5 Urethral reconstruction 20 6.3.6 Urine drainage and wound dressing 20 6.3.7 Outcome 20 6.4 References 21 7. -
Fearful Symmetries: Essays and Testimonies Around Excision and Circumcision. Rodopi
Fearful Symmetries Matatu Journal for African Culture and Society ————————————]^——————————— EDITORIAL BOARD Gordon Collier Christine Matzke Frank Schulze–Engler Geoffrey V. Davis Aderemi Raji–Oyelade Chantal Zabus †Ezenwa–Ohaeto TECHNICAL AND CARIBBEAN EDITOR Gordon Collier ———————————— ]^ ——————————— BOARD OF ADVISORS Anne V. Adams (Ithaca NY) Jürgen Martini (Magdeburg, Germany) Eckhard Breitinger (Bayreuth, Germany) Henning Melber (Windhoek, Namibia) Margaret J. Daymond (Durban, South Africa) Amadou Booker Sadji (Dakar, Senegal) Anne Fuchs (Nice, France) Reinhard Sander (San Juan, Puerto Rico) James Gibbs (Bristol, England) John A. Stotesbury (Joensuu, Finland) Johan U. Jacobs (Durban, South Africa) Peter O. Stummer (Munich, Germany) Jürgen Jansen (Aachen, Germany) Ahmed Yerma (Lagos, Nigeria)i — Founding Editor: Holger G. Ehling — ]^ Matatu is a journal on African and African diaspora literatures and societies dedicated to interdisciplinary dialogue between literary and cultural studies, historiography, the social sciences and cultural anthropology. ]^ Matatu is animated by a lively interest in African culture and literature (including the Afro- Caribbean) that moves beyond worn-out clichés of ‘cultural authenticity’ and ‘national liberation’ towards critical exploration of African modernities. The East African public transport vehicle from which Matatu takes its name is both a component and a symbol of these modernities: based on ‘Western’ (these days usually Japanese) technology, it is a vigorously African institution; it is usually -
Aguide to Evidence-Based Practices
A GUIDE TO EVIDENCE-BASED PRACTICES for INDIVIDUALS WITH DEVELOPMENTAL DISABILITIES This report was produced with the support of the Saginaw County Community Mental Health Authority May 2009 Compiled by Barbara Glassheim This document may not be reproduced or distributed without the express permission of SCCMHA A GUIDE TO EVIDENCE-BASED PRACTICES FOR INDIVIDUALS WITH DEVELOPMENTAL DISABILITIES V. 1.0 TABLE OF CONTENTS FORWARD ............................................................................................................... 1 EXECUTIVE SUMMARY ............................................................................................. 2 INTRODUCTION ....................................................................................................... 4 AN OVERVIEW OF EVIDENCE-BASED PRACTICE CONCEPTS ........................................... 7 CULTURAL CONSIDERATIONS ................................................................................. 10 MALTREATMENT ................................................................................................ 10 WOMEN ............................................................................................................. 11 OLDER ADULTS .................................................................................................. 11 ETHNIC GROUPS ................................................................................................ 12 DEAF CULTURE .................................................................................................. 13 EMPOWERMENT -
Gender Confirmation Surgery Reference Number: PA.CP.MP.95 Effective Date: 01/18 Coding Implications Last Review Date: 09/17 Revision Log
Clinical Policy: Gender Confirmation Surgery Reference Number: PA.CP.MP.95 Effective Date: 01/18 Coding Implications Last Review Date: 09/17 Revision Log Description Services for gender confirmation most often include hormone treatment, counseling, psychotherapy, complete hysterectomy, bilateral mastectomy, chest reconstruction or augmentation as appropriate, genital reconstruction, facial hair removal, and certain facial plastic reconstruction. Not every individual will require each intervention so necessity needs to be considered on an individualized basis. This criteria outlines medical necessity criteria for gender confirmation surgery when such services are included under the members’ benefit plan contract provisions. Policy/Criteria It is the policy of Pennsylvania Health and Wellness® (PHW) that the gender confirmation surgeries listed in section III are considered medically necessary for members when diagnosed with gender dysphoria per criteria in section I and when meeting eligibility criteria in section II. I. Gender Dysphoria Criteria, meets A and B A. Marked incongruence between the member’s experienced/expressed gender and assigned gender, of at least 6 month’s duration, as indicated by two or more of the following: 1. Marked incongruence between the member’s experienced/expressed gender and primary and/or secondary sex characteristics; 2. A strong desire to be rid of one’s primary and/or secondary sex characteristics because of a marked incongruence with one’s experienced/expressed gender; 3. A strong desire for the primary and/or secondary sex characteristics of the other gender; 4. A strong desire to be of the other gender (or some alternative gender different from one’s assigned gender); 5. A strong desire to be treated as the other gender (or some alternative gender different from one’s assigned gender); 6. -
Gtg-No-20B-Breech-Presentation.Pdf
Guideline No. 20b December 2006 THE MANAGEMENT OF BREECH PRESENTATION This is the third edition of the guideline originally published in 1999 and revised in 2001 under the same title. 1. Purpose and scope The aim of this guideline is to provide up-to-date information on methods of delivery for women with breech presentation. The scope is confined to decision making regarding the route of delivery and choice of various techniques used during delivery. It does not include antenatal or postnatal care. External cephalic version is the topic of a separate RCOG Green-top Guideline No. 20a: ECV and Reducing the Incidence of Breech Presentation. 2. Background The incidence of breech presentation decreases from about 20% at 28 weeks of gestation to 3–4% at term, as most babies turn spontaneously to the cephalic presentation. This appears to be an active process whereby a normally formed and active baby adopts the position of ‘best fit’ in a normal intrauterine space. Persistent breech presentation may be associated with abnormalities of the baby, the amniotic fluid volume, the placental localisation or the uterus. It may be due to an otherwise insignificant factor such as cornual placental position or it may apparently be due to chance. There is higher perinatal mortality and morbidity with breech than cephalic presentation, due principally to prematurity, congenital malformations and birth asphyxia or trauma.1,2 Caesarean section for breech presentation has been suggested as a way of reducing the associated perinatal problems2,3 and in many countries in Northern Europe and North America caesarean section has become the normal mode of breech delivery.