Conference Guide and Program
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Xpert MTB/RIF
Pandie et al. BMC Medicine 2014, 12:101 http://www.biomedcentral.com/1741-7015/12/101 RESEARCH ARTICLE Open Access Diagnostic accuracy of quantitative PCR (Xpert MTB/RIF) for tuberculous pericarditis compared to adenosine deaminase and unstimulated interferon-γ in a high burden setting: a prospective study Shaheen Pandie1†, Jonathan G Peter2,3†, Zita S Kerbelker1, Richard Meldau2, Grant Theron2, Ureshnie Govender2, Mpiko Ntsekhe1, Keertan Dheda2,4† and Bongani M Mayosi1,4*† Abstract Background: Tuberculous pericarditis (TBP) is associated with high morbidity and mortality, and is an important treatable cause of heart failure in developing countries. Tuberculous aetiology of pericarditis is difficult to diagnose promptly. The utility of the new quantitative PCR test (Xpert MTB/RIF) for the diagnosis of TBP is unknown. This study sought to evaluate the diagnostic accuracy of the Xpert MTB/RIF test compared to pericardial adenosine deaminase (ADA) and unstimulated interferon-gamma (uIFNγ) in suspected TBP. Methods: From October 2009 through September 2012, 151 consecutive patients with suspected TBP were enrolled at a single centre in Cape Town, South Africa. Mycobacterium tuberculosis culture and/or pericardial histology served as the reference standard for definite TBP. Receiver-operating-characteristic curve analysis was used for selection of ADA and uIFNγ cut-points. Results: Of the participants, 49% (74/151) were classified as definite TBP, 33% (50/151) as probable TBP and 18% (27/151) as non TBP. A total of 105 (74%) participants were human immunodeficiency virus (HIV) positive. Xpert-MTB/RIF had a sensitivity and specificity (95% confidence interval (CI)) of 63.8% (52.4% to 75.1%) and 100% (85.6% to 100%), respectively. -
UCT News Issue 10
April 2016 UCT News Issue 10 Join UCT's online community Journeys through academia: In this latest edition of UCT News, we track the unexpected twists and turns taken by UCT staff and students on their journeys to and through higher education. For more stories like these, keep an eye on the UCT website. How can we transform the professoriate? Dean-designate Bongani Mayosi outlines what can be done to grow and fast-track a new cohort of black and women professors in the Faculty of Health Sciences, using his own career path as a case study. Read more ... Activities News Make a name for yourself: Activist-academic: Rashida “History is like a puzzle”: How a university buildings are under Manjoo's journey from clothing master’s student pieced together review, and UCT wants your input factory clerk to UN investigator of the details of UCT's first black violence against women medical doctor How the Drama Department When an inspiring lecturer PhD student and indigenous interprets South Africa through changes your life’s course: language programmer Joan local lenses, using works from Introducing Ingrid Woolard, Byamugisha’s story is a lesson in SA playwrights UCT’s new dean of commerce persistence What's on at UCT? Find out more How toolmaker-turned-teacher Postdoctoral fellow Tana Joseph’s about university concerts, Gideon Nomdo ended up journey to the stars began when seminars, talks and public lectures recruiting young black students she was 11 with a scrapbook of into academia Hubble images Make it here Applications for study at UCT in 2017 are now open. -
Magdi Yacoub: King Responsibility Effect of Hearts...Saved the Lives of Thousands of Reports 40 -47 People
www.eiod.org October - December 2010 Magazine publishedby EIoD October -December2010Issue12 Not for Sale for Not Executive Director’s Letter MANAGEMENT AND BOARD: A POINT OF STRENGTH OR WEAKNESS The relationship between Boards and management is one of the main reasons for success or failure of companies. Moreover, board-management relationship has direct impact on the future of companies and their ability to protect shareholders rights. Hence the Egyptian code of corporate governance covers this relationship in a detailed manner. I may not be exaggerating if I say that that this relationship is one of the major challenges facing companies that EIoD sees evident in dealing with various types of businesses. Basically, the General Assembly, GA, or owners of the company elects the board to oversee the executive management, and to make sure that the company has all the ingredients for success, including internal controls, risk management, strategic management, and all the other systems and work procedures. The board is also responsible for the appointment of a CEO, or the top executive, and determines overall goals and achievements expected from the management. Furthermore, directors use their relationships with various stakeholders to support the company’s activities and to open new markets. The General Assembly is to monitor and evaluate the Board performance, and decides whether to keep it, to change some of its members or to change it completely. Therefore, it is important that the GA members are not themselves company directors. If this is the case, it means that the board is accountable to itself in the form of the GA. -
Graduation Ceremonies December 2019
GRADUATION CEREMONIES DECEMBER 2019 CONTENTS Morning Ceremony – Thursday 12 December at 10h00............................................................……...3 Faculties of Health Sciences 1 and Law Afternoon Ceremony – Thursday 12 December at 15h00 ………..............….........…………………22 Faculties of Engineering & the Built Environment and Science Morning Ceremony – Friday 13 December at 09h00 …………................……................…………..48 Faculty of Humanities Afternoon Ceremony – Friday 13 December at 14h00 …….....…………..............................………66 Faculty of Commerce Evening Ceremony – Friday 13 December at 18h00 …………................……................…………..78 Faculty of Health Sciences 2 NATIONAL ANTHEM Nkosi sikelel’ iAfrika Maluphakanyisw’ uphondolwayo, Yizwa imithandazo yethu, Nkosi sikelela, thina lusapho lwayo. Morena boloka etjhaba sa heso, O fedise dintwa la matshwenyeho, O se boloke, O se boloke setjhaba sa heso, Setjhaba sa South Afrika – South Afrika. Uit die blou van onse hemel, Uit die diepte van ons see, Oor ons ewige gebergtes, Waar die kranse antwoord gee, Sounds the call to come together, And united we shall stand, Let us live and strive for freedom, In South Africa our land. 2 FACULTIES OF HEALTH SCIENCES (CEREMONY 1) AND LAW ORDER OF PROCEEDINGS Academic Procession. (The congregation is requested to stand as the procession enters the hall) The Presiding Officer will constitute the congregation. The National Anthem. The University Dedication will be read by a member of the SRC. Musical Item. Welcome by the Master of Ceremonies. The Master of Ceremonies will present Peter Zilla for the award of a Fellowship. The graduands and diplomates will be presented to the Presiding Officer by the Deans of the faculties. The Presiding Officer will congratulate the new graduates and diplomates. The Master of Ceremonies will make closing announcements and invite the congregation to stand. -
2 Meeting PASCAR Task Force on Hypertension London, UK, August
2nd Meeting PASCAR Task Force on Hypertension London, UK, August 30, 2015 Update on PASCAR HT Roadmap & EBM review & purpose of the meeting Anastase Dzudie Chair: PASCAR HT Task Force Hypertension in Africa From 80 millions HT in 2000 to … 150 million in 2025 Unless we actact!! PASCAR recommendations of priority interventions to ministries of health for prevention of heart disease, diabetes and stroke in the African region: The 10 “Best buys” (Bongani Mayosi, Heart, 2013) Outcome of the Nairobi meeting Outcome of the Nairobi meeting The burden of raised BP in Africa is huge Need for a clear policy program & guidelines, several limitations: Need for outcome data Need to search for existing drug evidence (Clinical trials) Anticipated lack of evidence Outcome of the Nairobi meeting THE CREOLE TRIAL PROJECT TITLE : Compa rison of Thr ee Combination Therapies in Lowering Blood Pressure in Black Africans (The CREOLE study). RESEARCH TEAM: PI: Dike Ojji (Co-chair, PASCAR Task Force on Hypertension). Co-PI: Neil Poulter Investigators Cameroon (1): Anastase Dzudie (Douala); Kenya (2):Elijah Ogola (Nairobi), and Ayub Barasa (Eldoret); Mozambique (1): Albertino Damasceno (Maputo); Nigeria (3): Egenti Nonye and Manmak Mamven (Abuja), Okechukwu Ogah (Ibadan), and Mahmoud Sani (Kano);South Africa (2): Biddy Buchanan Lee and Ikechi Okpechi (Cape Town), Gboyega Ogunbanjo and Phindile Mntla (Ga Rankuwa); Uganda (1): Charles Mondo (Kampala) Outcome of the Nairobi meeting Health Decision Model to address BP control Patient Characteristics Policy Provider Characteristics Perceived Cognition Communication Medication Risks Style Regimen Coping & Literacy Treatment Stress Intensity of Guidelines Therapy Adherence Comorbidities Side Effects Medical Environment : Depression health systems etc. -
Proceedings of the British Cardiac Society
Br Heart J: first published as 10.1136/hrt.36.10.1031 on 1 October 1974. Downloaded from British Heart_Journal, I974, 36, 103I-I039. Proceedings of the British Cardiac Society THE FIFTY-THIRD ANNUAL GENERAL MEET- 4 Hollman, previously Honorary Assistant Secretary, ING of the British Cardiac Society was held at the was elected Honorary Secretary. Curtis Auditorium of the Physics Building in the University of Newcastle upon Tyne on Thursday, i8 5 Three members were nominated for Honorary Assis- April I974. The President, JoHN GOODWIN, took the tant Secretary. Miller polled the most votes and was, Chair at 9.oo a.m. during Private Business. At the therefore, elected. Scientific Session the Chair was taken by H. A. DEWAR The President thanked Sowton for his work during his in the morning and by F. S. JACKSON in the afternoon. term of office as Honorary Secretary, which included instituting the Young Research Workers' Prize. He had Private Business also started to organize the joint meeting with the I The Secretary reported that the Minutes of the Swedish Society in I975, and his offer to continue with Autumn Meeting in December I973 had not yet been this on behalf of the British Cardiac Society was very published in the British Heart Journal because of much appreciated. printing difficulties.' 6 Barber would continue as a co-opted Council Member, 2 The following Ordinary Members were elected: and on a postal vote Abrams had polled the most votes and was therefore elected to replace Donald Ross on the Philip Kennedy Caves (SM) Edinburgh Council. -
JAAC-AHC-Amelia.Pdf
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY VOL. 72, NO. 12, 2018 ª 2018 BY THE AMERICAN COLLEGE OF CARDIOLOGY FOUNDATION PUBLISHED BY ELSEVIER JACC INTERNATIONAL Professor Sir Magdi Yacoub and the Aswan Heart Centre Amelia Scholtz, PHD etween myectomies, Professor Sir Magdi 1.5 million residents, Aswan was a natural choice for B Yacoub spoke with Amelia Scholtz about the a cardiac research and treatment facility that would bustling present and promising future of the realize Yacoub’s dream of more lasting, widespread Aswan Heart Centre. improvements for cardiovascular health in Egypt. Professor Sir Magdi Yacoub, OM, FRS, is now a He established the Aswan Heart Centre (AHC) in legend in cardiac surgery. He helped initiate a new 2009asaprojectofChainofHope,acharityalso era of heart transplantation in the United Kingdom in founded by Yacoub. With a continuing stream of the 1980s and pioneered surgical techniques such as donations from Egyptians rich and poor, as well as the Ross procedure, the modern arterial switch, and, partnerships with universities and health care or- more recently, a modified Mustard operation. His ganizations around the world, the AHC is now a achievements have been recognized with a British tertiary referral center serving patients not only knighthood and numerous honorary degrees. from the Aswan region, but also from other parts of Long before these successes, Yacoub—with his Egypt and Africa. In addition to its 96 patientbeds,2 mother and siblings—spent his early years following operating rooms, intensive care facilities, cardiac his surgeon father around Egypt on a path deter- catheterization laboratories, patient examination mined by medical need and government imperatives. -
Surgical Research Report 2017/18
Surgical Research Report 2017/18 The Royal College of Surgeons of England Contents 4 Chairman’s Introduction 6 Research Fellows’ Reports 60 Pump Priming Reports 68 Surgical Trials Initiative 72 Clinical Effectiveness Unit 76 Research in the Faculty of Dental Surgery 80 Prizes & Travelling Awards 82 Higher Degrees for Intercalated Medical Students 92 Elective Prize Reports 102 Lectures Delivered in 2015–2016 103 Fundraising in Focus 104 Picture Gallery 2 3 Chairman’s introduction Research is not an optional add-on, it is the very lifeblood of surgery. We need to introduce new technologies safely and effectively, we need to understand basic mechanisms of disease and we need to do the things we are doing now, but better. Most important of all, we need to inspire the surgeons of the future to see this as part of their mission in improving the experience and standards of care for our patients. Neil Mortensen Chairman, Research Fellowship and Lectureship Selection Group 4 The Royal College of Surgeons The Surgical Trials Initiative introduced Professor Sir Peter Morris who with through its Research Fellowship in 2012 has developed rapidly. There great foresight started the Research scheme has committed more than are now seven chosen Surgical Trial Fellowship scheme in 1993 has £40million to support over 700 Centres in the UK and there are 15 recently retired as Director of the individual trainee members during appointed Surgical Specialty Leads Centre for Evidence in Transplantation. the past 24 years, and this year we with the task of promoting trials and We are particularly grateful to Claire have approved a further £2million trial recruitment, and providing a link Large who has retired as CEO of funding for some 30 new Research between surgeons, investigators the Dunhill Medical Trust, who have Fellowships. -
Genetic Susceptibility to Acute Rheumatic Fever: a Systematic Review and Meta-Analysis of Twin Studies
Genetic Susceptibility to Acute Rheumatic Fever: A Systematic Review and Meta-Analysis of Twin Studies Mark E. Engel1, Raphaella Stander1, Jonathan Vogel1, Adebowale A. Adeyemo2, Bongani M. Mayosi1* 1 Department of Medicine, Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa, 2 Center for Research in Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America Abstract Background: Acute rheumatic fever is considered to be a heritable condition, but the magnitude of the genetic effect is unknown. The objective of this study was to conduct a systematic review and meta-analysis of twin studies of concordance of acute rheumatic fever in order to derive quantitative estimates of the size of the genetic effect. Methods: We searched PubMed/MEDLINE, ISI Web of Science, EMBASE, and Google Scholar from their inception to 31 January 2011, and bibliographies of retrieved articles, for twin studies of the concordance for acute rheumatic fever or rheumatic heart disease in monozygotic versus dizygotic twins that used accepted diagnostic criteria for acute rheumatic fever and zygosity without age, gender or language restrictions. Twin similarity was measured by probandwise concordance rate and odds ratio (OR), and aggregate probandwise concordance risk was calculated by combining raw data from each study. ORs from separate studies were combined by random-effects meta-analysis to evaluate association between zygosity status and concordance. Heritability was estimated by fitting a variance components model to the data. Results: 435 twin pairs from six independent studies met the inclusion criteria. The pooled probandwise concordance risk for acute rheumatic fever was 44% in monozygotic twins and 12% in dizygotic twins, and the association between zygosity and concordance was strong (OR 6.39; 95% confidence interval, 3.39 to 12.06; P,0.001), with no significant study heterogeneity (P = 0.768). -
Professor of Cardiothoracic Surgery
PROFESSOR SIRMAGDIYACOUB Faculty of Medicine, National Heart & Lung Institute Professor of Cardiothoracic Surgery Sir Magdi Yacoub is Professor of Cardiothoracic Surgery at the National Heart and Lung Institute, Imperial College London and Founder and Director of Research at the Harefield Heart Science Centre (Magdi Yacoub Institute) overseeing over 60 scientists and students in the areas of tissue engineering, myocardial regeneration, stem cell biology, end stage heart failure and transplant immunology. He is also Founder and Director of Magdi Yacoub Research Network which has created the Qatar Cardiovascular Research Center in collaboration with Qatar Foundation and Hamad Medical Corporation. Professor Yacoub was born in Egypt and graduated from Cairo University Medical School in 1957, trained in London and held an Assistant Professorship at the University of Chicago. He is a former BHF Professor of Cardiothoracic Surgery for over 20 years and Consultant Cardiothoracic Surgeon at Harefield Hospital from 1969-2001 and Royal Brompton Hospital from 1986-2001. Professor Yacoub established the largest heart and lung transplantation programme in the world where more than 2,500 transplant operations have been performed. He has also developed novel operations for a number of complex congenital heart anomalies. He was knighted for his services to medicine and surgery in 1991, awarded Fellowship of the Academy of Medical Sciences in 1998 and Fellowship of The Royal Society in 1999. A lifetime outstanding achievement award in recognition of his contribution to medicine was presented to Professor Yacoub by the Secretary of State for Health in the same year. Research led by Professor Yacoub include tissue engineering heart valves, myocardial regeneration, novel left ventricular assist devices and wireless sensors with collaborations within Imperial College, nationally and internationally. -
The Burden of Depression and Anxiety Among Medical Students in South Africa: a Cross-Sectional Survey at the University of Cape Town
This open-access article is distributed under Creative Commons licence CC-BY-NC 4.0. RESEARCH The burden of depression and anxiety among medical students in South Africa: A cross-sectional survey at the University of Cape Town S van der Walt;1* W S Mabaso;1* E L Davids,2,3 BPsych, MA, PhD; P J de Vries,2 MB ChB, FRCPsych, PhD 1 Final-year medical student, Faculty of Health Sciences, University of Cape Town, South Africa 2 Adolescent Health Research Unit, Division of Child and Adolescent Psychiatry, Faculty of Health Sciences, University of Cape Town, South Africa 3 Cochrane South Africa, South African Medical Research Council, South Africa * Joint first authors. Corresponding authors: S van der Walt ([email protected]), W S Mabaso ([email protected]) Background. Depressive and anxiety disorders occur at very high rates among medical students. For instance, an international review and meta-analysis estimated the overall pooled crude prevalence of depression or depressive symptoms at 27.2%. However, South African (SA) data are very limited. Objectives. To determine rates of depression and anxiety among medical students and to examine the associations with various sociodemographic variables (biological sex, gender identity, household income, ethnicity, and clinical v. pre-clinical students). We also examined whether the ‘mini-semester’ of 2017 resulting from the 2016 ‘Fees Must Fall’ student protests was associated with increased depression/anxiety. Methods. The study was a cross-sectional electronic survey conducted in the Faculty of Health Sciences, University of Cape Town, using an anonymous, self-administered online questionnaire. The questionnaire included basic sociodemographic questions, the Patient Health Questionnaire-9 and the Hospital Anxiety and Depression Scale. -
In Memoriam, Professor Bongani Mayosi (1967–2018) Jean B
Nachega et al. Pilot and Feasibility Studies (2018) 4:154 https://doi.org/10.1186/s40814-018-0348-7 EDITORIAL Open Access Advancing global health through cardiovascular research, mentorship, and capacity building: in memoriam, professor Bongani Mayosi (1967–2018) Jean B. Nachega2, Mpiko Ntsekhe3, Jimmy Volmink4 and Lehana Thabane1* (Cum Laude) in 1989 and also met his wife, Professor and Head of Dermatology, Nonhlanhla Khumalo, in their first week of medical school. In 1990, the pair made their way to Port Elizabeth to work at the Livingstone Hospital as interns, before moving to Cape Town to es- tablish long-term careers. After completing his specialist training in internal medicine and cardiology at the Uni- versity of Cape Town (UCT), Professor Mayosi moved to Oxford University, UK, on a prestigious Nuffield Medical Fellowship where he completed a D.Phil. in car- diovascular genetics at the Wellcome Trust Centre for Human Genetics. Upon returning to Cape Town in 2001‚ Professor Mayosi assumed research‚ teaching, and clinical respon- sibilities in Internal Medicine and Cardiology at UCT and Groote Schuur Hospital, coincidentally the place in which the world’s first human heart transplant took place during the year of his birth. Five years later‚ at the age of 38‚ he became the first black faculty member to We are deeply saddened by the passing of Professor be made Professor and Head of the Department of Bongani Mayosi. Bongani was one of the inaugural Medicine. board members of Pilot and Feasibility Studies. He con- tributed greatly to the design and conduct of pilot and feasibility studies in cardiovascular research.