The Wuhan Coronavirus and Its Impact on China's Foreign Relations
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Ideological Responses to the Coronavirus Pandemic: China and Its Other
IDEOLOGICAL RESPONSES TO THE CORONAVIRUS PANDEMIC: CHINA AND ITS OTHER Samuli Seppänen† Abstract This Article discusses the ongoing coronavirus pandemic as an instance of ideological contestation between the People’s Republic of China and its ideological Other—the “Western” liberal democracies. Much of this ideological contestation highlights the idiosyncratic aspects of opposing ideological narratives. From the illiberal perspective, promoters of liberal narratives on governance and public health can be said to focus too much on procedural legitimacy and, consequently, appear to be ill-placed to acknowledge and respond to public health emergencies. Conversely, from the liberal perspective, advocates of illiberal narratives appear to be responding to a never-ending emergency and, consequently, seem unable to take full advantage of procedural legitimacy and rule-based governance in order to prevent public health emergencies from occurring. The coronavirus pandemic also exposes the aspirational qualities of both ideological narratives. On one hand, it appears aspirational to assume that the coronavirus response in liberal democratic countries can be based on the respect for individual freedom, human dignity, and other liberal first principles. On the other hand, the image of a strong, stable government projected by the CCP also seems to be based on aspirational notions about the coherence and resilience of the P.R.C.’s governance project. In the middle of the pandemic, it appears that the coronavirus follows no ideological script. † Associate Professor, The Chinese University of Hong Kong, Faculty of Law. Published by Penn Law: Legal Scholarship Repository, 2020 2020] U. PA. ASIAN L. REV. 25 Abstract ................................................................................... 24 I. INTRODUCTION ......................................................................... 25 II. -
Coinfection and Other Clinical Characteristics of COVID-19 In
Coinfection and Other Clinical Characteristics of COVID-19 in Children Qin Wu, MD,a,p Yuhan Xing, MD,b,p Lei Shi, MB,a,p Wenjie Li, MS,a Yang Gao, MS,a Silin Pan, PhD, MD,a Ying Wang, MS,c Wendi Wang, MS,a Quansheng Xing, PhD, MDa BACKGROUND AND OBJECTIVES: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is abstract a newly identified pathogen that mainly spreads by droplets. Most published studies have been focused on adult patients with coronavirus disease 2019 (COVID-19), but data concerning pediatric patients are limited. In this study, we aimed to determine epidemiological characteristics and clinical features of pediatric patients with COVID-19. METHODS: We reviewed and analyzed data on pediatric patients with laboratory-confirmed COVID-19, including basic information, epidemiological history, clinical manifestations, laboratory and radiologic findings, treatment, outcome, and follow-up results. RESULTS: A total of 74 pediatric patients with COVID-19 were included in this study. Of the 68 case patients whose epidemiological data were complete, 65 (65 of 68; 95.59%) were household contacts of adults. Cough (32.43%) and fever (27.03%) were the predominant symptoms of 44 (59.46%) symptomatic patients at onset of the illness. Abnormalities in leukocyte count were found in 23 (31.08%) children, and 10 (13.51%) children presented with abnormal lymphocyte count. Of the 34 (45.95%) patients who had nucleic acid testing results for common respiratory pathogens, 19 (51.35%) showed coinfection with other pathogens other than SARS-CoV-2. Ten (13.51%) children had real-time reverse transcription polymerase chain reaction analysis for fecal specimens, and 8 of them showed prolonged existence of SARS-CoV-2 RNA. -
CONNECTION the Official Newsletter of Zhejiang University Issue 16 Feb.2020
CONNECTION The Official Newsletter of Zhejiang University Issue 16 Feb.2020 COVID-19 Special Issue Stand Strong Message from Editor-in-Chief CONNECTION Welcome to the special COVID-19 issue of Issue 16 CONNECTION, which highlights the efforts and contributions of ZJU community in face of the epidemic. As a group, they are heroes in harm's way, givers and doers who respond swiftly to the need of our city, our country and the world. When you read their stories, you'll recognize the strength and solidarity that define all ZJUers. ZJU community has demonstrated its courage and resilience in the battle against the novel coronavirus. At this time, let us all come together to protect ourselves and our loved ones, keep all those who are at the front lines in our prayers and pass on our gratitude to those who have joined and contributed to the fight against the virus. Together, we will weather this crisis. LI Min, Editor-in-Chief Director, Office of Global Engagement Editorial office : Global Communications Office of Global Engagement, Zhejiang University 866 Yuhangtang Road, Hangzhou, P.R. China 310058 Phone: +86 571 88981259 Fax: +86 571 87951315 Email: [email protected] Edited by : CHEN Weiying, AI Ni Designed by : HUANG Zhaoyi Material from Connection may be reproduced accompanied with appropriate acknowledgement. CONTENTS Faculty One of the heroes in harm’s way: LI Lanjuan 03 ZJU medics answered the call from Wuhan 04 Insights from ZJU experts 05 Alumni Fund for Prevention and Control of Viral Infectious Diseases set up 10 Alumni community mobilized in the battle against COVID-19 11 Education Classes start online during the epidemic 15 What ZJUers feel about online learning 15 Efforts to address concerns, avoid misinformation 17 International World standing with us 18 International students lending a hand against the epidemic 20 What our fans say 21 FacultyFaculty ZJU community has taken on the responsibility to join the concertedZJU community efforts has takenagainst on thethe responsibility spreadto join the of concerted the virus. -
Democratic Values and the COVID-19 Response
Dr. Li Wenliang, the man who first identified Covid-19, had the chance to tell people about the lives soon to be at stake. The one thing standing in his way? His government. Following the weeks after Dr. Li’s discovery and outreach to other doctors, police came to his house on multiple occasions to tell him to stop. At one point, he was summoned to the Chinese Public Security Bureau, where he was met by officials claiming that he was disturbing public order. Dr. Li was trying to warn the medical community about a threat that would span the world and kill at least half a million people within a matter of months, but the very people meant to protect him took his voice away. The passing of Dr. Li in early February to Covid-19 serves as a stark reminder of the impact that authoritarian rule has over more than 50 countries today. As nations search for the most effective ways to combat Covid-19, the authoritarian policies employed by dictatorships have the potential to spread elsewhere. Covid-19 has not just endangered our health, but our right to experience life with liberties too. The freedom and right to prosperity that I and others have enjoyed may now be at risk due to democracies taking a more intrusive approach towards containing the virus. Democratic nations need to ensure that citizen's liberties are not sacrificed for the “greater good”. Thus, democracies must strike a balance between doing everything in their power to stop Covid-19 without infringing on the rights of their people. -
1. Sars-Cov Nucleocapsid Protein Epitopes and Uses Thereof
www.engineeringvillage.com Citation results: 500 Downloaded: 4/24/2020 1. SARS-COV NUCLEOCAPSID PROTEIN EPITOPES AND USES THEREOF KELVIN, David; PERSAD, Desmond; CAMERON, Cheryl; BRAY, Kurtis, R.; LOFARO, Lori, R.; JOHNSON, Camille; SEKALY, Rafick-Pierre; YOUNES, Souheil-Antoine; CHONG, Pele Assignee: UNIVERSITY HEALTH NETWORK; BECKMAN COULTER, INC.; UNIVERSITE DE MONTREAL; NATIONAL HEALTH RESEARCH INSTITUTES Publication Number: WO2005103259 Publication date: 11/03/2005 Kind: Patent Application Publication Database: WO Patents Compilation and indexing terms, 2020 LexisNexis Univentio B.V. Data Provider: Engineering Village 2. SARS-CoV-specific B-cell epitope and applications thereof Wu, Han-Chung; Liu, I-Ju; Chiu, Chien-Yu Assignee: National Taiwan University Publication Number: US20060062804 Publication date: 03/23/2006 Kind: Utility Patent Application Database: US Patents Compilation and indexing terms, 2020 LexisNexis Univentio B.V. Data Provider: Engineering Village 3. A RECOMBINANT SARS-COV VACCINE COMPRISING ATTENUATED VACCINIA VIRUS CARRIERS QIN, Chuan; WEI, Qiang; GAO, Hong; TU, Xinming; CHEN, Zhiwei; ZHANG, Linqi; HO, David, D. Assignee: INSTITUTE OF LABORATORY ANIMAL SCIENCE OF CHINESE ACADEMY OF MEDICAL SCIENCES; THE AARON DIAMOND AIDS RESEARCH CENTER; QIN, Chuan; WEI, Qiang; GAO, Hong; TU, Xinming; CHEN, Zhiwei; ZHANG, Linqi; HO, David, D. Publication Number: WO2006079290 Publication date: 08/03/2006 Kind: Patent Application Publication Database: WO Patents Compilation and indexing terms, 2020 LexisNexis Univentio B.V. Data -
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1 2 Parallel pandemics illustrate the need for One Health solutions 3 4 Authors: Claire Tucker1, Anna Fagre1, George Wittemyer2, Tracy Webb3, Edward Okoth 5 Abworo4, Sue VandeWoude*5 6 7 8 1Department of Microbiology, Immunology, Pathology. College of Veterinary Medicine and 9 Biomedical Sciences. Colorado State University. Fort Collins, Colorado; 2 Department of Fish, 10 Wildlife, and Conservation Biology. Warner College of Natural Resources. Colorado State 11 University. Fort Collins, Colorado; 3 Department of Clinical Sciences. College of Veterinary 12 Medicine and Biomedical Sciences. Colorado State University. Fort Collins, Colorado; 13 4International Livestock Research Institute. Nairobi, Kenya; 5 Corresponding Author: Sue 14 VandeWoude, DVM, PhD, Department of Microbiology, Immunology, Pathology. College of 15 Veterinary Medicine and Biomedical Sciences. Colorado State University. Fort Collins, 16 Colorado. [email protected]. https://orcid.org/0000-0001-9227-1622. 17 18 19 20 21 22 23 24 1 25 Abstract 26 African Swine Fever (ASF) was reported in domestic pigs in China in 2018. This highly 27 contagious viral infection with no effective vaccine reached pandemic proportions by 2019, 28 substantially impacting protein availability in the same region where the COVID-19 pandemic 29 subsequently emerged. We discuss the genesis, spread, and wide-reaching impacts of an 30 epidemic in a vital livestock species, noting parallels and potential contributions to ignition of 31 COVID-19. We speculate about follow-on impacts of these pandemics on global public health 32 infrastructure and suggest intervention strategies using a cost: benefit approach for low-risk, 33 massive-impact events. We note that substantive changes in how the world reacts to potential 34 threats will be required to overcome catastrophes driven by climate change, food insecurity, lack 35 of surveillance infrastructure and other gaps. -
COVID-19 and China: a Chronology of Events (December 2019-January 2020)
COVID-19 and China: A Chronology of Events (December 2019-January 2020) Updated May 13, 2020 Congressional Research Service https://crsreports.congress.gov R46354 SUMMARY R46354 COVID-19 and China: A Chronology of Events May 13, 2020 (December 2019-January 2020) Susan V. Lawrence In Congress, multiple bills and resolutions have been introduced related to China’s Specialist in Asian Affairs handling of a novel coronavirus outbreak in Wuhan, China, that expanded to become the coronavirus disease 2019 (COVID-19) global pandemic. This report provides a timeline of key developments in the early weeks of the pandemic, based on available public reporting. It also considers issues raised by the timeline, including the timeliness of China’s information sharing with the World Health Organization (WHO), gaps in early information China shared with the world, and episodes in which Chinese authorities sought to discipline those who publicly shared information about aspects of the epidemic. Prior to January 20, 2020—the day Chinese authorities acknowledged person-to-person transmission of the novel coronavirus—the public record provides little indication that China’s top leaders saw containment of the epidemic as a high priority. Thereafter, however, Chinese authorities appear to have taken aggressive measures to contain the virus. The Appendix includes a concise version of the timeline. A condensed version is below: Late December: Hospitals in Wuhan, China, identify cases of pneumonia of unknown origin. December 30: The Wuhan Municipal Health Commission issues “urgent notices” to city hospitals about cases of atypical pneumonia linked to the city’s Huanan Seafood Wholesale Market. The notices leak online. -
Social Media and China's Virus Outbreak
Volume 18 | Issue 14 | Number 6 | Article ID 5418 | Jul 15, 2020 The Asia-Pacific Journal | Japan Focus Social Media and China's Virus Outbreak Anonymous China rules the world” (2009). In an interview Abstract: In the early stage of the coronavirus with the state media CCTV, Jacques praised the outbreak in China, social media were bursting Chinese government’s crisis management with anger and desperation. Many pleaded for capacity in the wake of the pandemic, saying medical help, called for public attention to the that this, “can be a historic moment where unattended and asked for accountability for people come to see what the strengths of the local officials who failed to respond to the Chinese system are.” (Tuwen Ouni 2020) public health crisis in time. But with the epicenter shifting to Europe and NorthThis marked a dramatic turnaround from the America, a series of social media tactics, early stages of the pandemic when there was highlighting China’s successful containment speculation about whether the Chinese efforts, while disparaging foreign countries’ government’s legitimacy might be undermined responses, and spinning the origin of the by the pandemic. Public opinion in China on the coronavirus outbreak, facilitated a nationalist government’s handling of the crisis has also takeover of social media sites in China. experienced a rollercoaster ride, dipping to the bottom in early February and gradually recovering as the pandemic was contained. The state emerged from the crisis stronger than How China rewrites the narrative of the ever, trumpeting that it had led the Chinese coronavirus pandemic on social media people to victory in the war against COVID-19. -
Lopinavir/Ritonavir for COVID-19: a Living Systematic Review Doi: 10.5867/Medwave.2020.06.7966
Lopinavir/ritonavir for COVID-19: A living systematic review doi: 10.5867/medwave.2020.06.7966 Appendix 3: Included, excluded and ongoing studies - Lopinavir/ritonavir for COVID-19: A living systematic review Included randomised trials LOTUS China (1,2) Details or comments REFERENCES Publication thread for LOTUS China Epistemonikos Chen et al (1) Type: Journal article Epistemonikos | DOI ChiCTR2000029387 (2) Type:Trial registry (Chinese Clinical Trial Registry) Epistemonikos | DOI (not available) STUDY DESIGN QUOTE: ☑Randomised trial Single centre , open-label, individually randomized, controlled trial; ☐Comparative, non- randomised Eligible patients were randomly assigned in a 1:1 ratio; ☐Non-comparative study To balance the distribution of oxygen support between the two groups as an indicator of severity of respiratory failure, randomization was stratified on the basis of respiratory support methods at the time of enrollment: no oxygen support or oxygen support with nasal duct or mask, or high-flow oxygen, noninvasive ventilation, or invasive ventilation including ECMO. The permuted block (four patients per block) randomization sequence, including stratification, was prepared by a statistician not involved in the trial, using SAS software, version 9.4 (SAS Institute). POPULATION: INCLUSION QUOTE: CRITERIA Patients were assessed for eligibility on the basis of a positive reverse-transcriptase– ☐COVID-19 polymerase-chain-reaction (RT-PCR) assay) for SARS-CoV-2 in a respiratory tract ☑COVID-19 pneumonia sample Male and nonpregnant female patients 18 years of age or older were eligible if they had a diagnostic specimen that was positive on RT-PCR, had pneumonia ☐Severe COVID-19 pneumonia confirmed by chest imaging, had an oxygen saturation of 94% or less while they were breathing ambient air or a ratio of the partial pressure of oxygen to the fraction 1 / 27 Lopinavir/ritonavir for COVID-19: A living systematic review doi: 10.5867/medwave.2020.06.7966 of inspired oxygen at or below 300 mg Hg. -
Dr. Li Wenliang and the Time of COVID-19
EDITOR’S PAGE Dr. Li Wenliang and the Time of COVID-19 Johannes Czernin David Geffen School of Medicine at UCLA, Los Angeles, California do their job at times of great personal These are difficult times for all of us. None of us has ever risk. I am certain that you all share our experienced anything like the current pandemic. Nuclear medicine experience at UCLA: these are selfless clinics are usually very safe, low-risk, low-stress environments. people who help and support each This has changed now as each patient can be infected, and staff other; cover for each other; and volun- members can be asymptomatic carriers or become symptomatic teer to step in and up as needed. while providing services. Although mortality rates are low, the Dr. Li Wenliang was reprimanded huge number of infections poses enormous challenges for health- initially for ‘‘disrupting public order’’ care systems worldwide. Medical personnel are stretched to the in China when he first reported the out- limits. While this editorial was being written, one of our staff break in Wuhan. He died, and the Chi- members tested positive for COVID-19. How do you protect nese government has finally sent a Johannes Czernin patients and staff without discontinuing essential clinical services? ‘‘solemn apology’’ to him. There are many A specific example is provided by Dr. Zuckier et al. (1), who pro- more physicians, technologists, nurses, pose elimination of the ventilation portion from lung perfusion/ and administrators who fell severely ill or died. ventilation scans, as aerosols can be an infection source. These are our heroes. -
SARS-COV-2 in Ophthalmology, in Ophthalmology, SARS-COV-2 S, Et Al
SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice SARS-COV-2 em Oftalmologia: Evidência Atual e Recomendações para a Prática Clínica ARTIGO DE REVISÃO Sónia TORRES-COSTA1, Mário LIMA-FONTES1, Fernando FALCÃO-REIS1,2, Manuel FALCÃO1,2 Acta Med Port 2020 Sep;33(9):593-600 ▪ https://doi.org/10.20344/amp.14118 ABSTRACT Introduction: COVID-19 is caused by the coronavirus SARS-CoV-2. Ocular manifestations have been reported including conjunctivitis and retinal changes. Therefore, it is of the utmost importance to clarify eye involvement in COVID-19 in order to help with its diagnosis and to further prevent its transmission. The purpose of this review is to describe the structure and transmission of SARS-CoV-2, re- ported ocular findings and protection strategies for ophthalmologists. Material and Methods: Literature search on PubMed for relevant articles using the keywords ‘COVID-19’, ‘coronavirus’, and ‘SARS-CoV-2’ in conjunction with ‘ophthalmology’ and ‘eye’. Moreover, official recommendations of ophthalmological societies were reviewed. Results: Although the conjunctiva is directly exposed to extraocular pathogens, and the mucosa of the ocular surface and upper respi- ratory tract are connected by the nasolacrimal duct, the eye is rarely involved in human SARS-CoV-2 infection and the SARS-CoV-2 RNA positive rate by RT-PCR test in tears and conjunctival secretions from patients with COVID-19 is also extremely low. Discussion: The eye can be affected by SARS-CoV-2, which is supported by some reports of conjunctivitis and retinal changes, but its role in the spread of the disease is still unknown. -
Evaluating Incidence and Impact Estimates of the Coronavirus Outbreak from Wuhan Before Lockdown
Evaluating Incidence and Impact Estimates of the Coronavirus Outbreak from Wuhan before Lockdown Mai He, M.D., Ph.D., 1 Li Li, M.A.2, Louis P. Dehner, M.D.1 1. Department of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA 2. AT&T, Bedminster, NJ 07921, USA Corresponding author: Mai He, M.D., Ph.D. Department of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA Phone: (314) 273-1328 Email: [email protected] 1 Abstract Background: Wuhan, China was the original epicenter of COVID-19 pandemic. The goal of the current study is to understand the infection transmission dynamics before intervention measures were taken, such as issuing a lockdown for the city and other social distancing policies. Methods: Data and key events were searched through pubmed for medical literature and internet for Chinese government announcements and Chinese media reports. Epidemiological data including R0 and infection were calculated using data extracted from variety of data sources. Results: We established a timeline emphasizing evidence of human-to-human transmission. By January 1, 2020, Chinese authorities had been presented convincing evidence of human-to-human transmission; however, it was until January 20, 2020 that this information was shared with the public. Our study estimated that there would have been 10,989 total infected cases if interventions were taken on January 2, 2020, vs 239,875 cases when lockdown was put in place on January 23, 2020. Conclusions: China’s withholding of key information about the 2020 COVID-19 pandemic and its delayed response ultimately led to the largest public health crisis of this century and could have been avoided with earlier countermeasures.