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Th PM OS1 1: Pdes in Biomedical Image Analysis
TABLE OF CONTENTS Th_PM_OS1: PDEs in Biomedical Image Analysis A Template-Propagation Method for Segmentation of Filamentous Structures in Electron Tomograms...............................................................................1 Sriram Subramaniam, Peijun Zhang, David Germain, Tracey Rouault, NIH; Weicheng Shen, SAIC; A New Approach for 3D Segmentation of Cellular Tomograms Obtained Using Three-Dimensional Electron Microscopy ..........................................................5 Alberto Bartesaghi, Guillermo Sapiro, University of Minnesota; Stanton Lee, Jon Lefman, Sharon Wahl, Sriram Subramaniam, National Institutes of Health; Jan Orenstein, George Washington University; DT-MRI Estimation, Regularization and Fiber Tractography..................................9 Rachid Deriche, INRIA; David Tschumperle, INRIA; Christophe Lenglet, INRIA A Hybrid 3D Segmentation Framework.....................................................................13 Dimitris Metaxas, Rutgers University Variational Methods and Partial Differential Equations in Cardiac Image Analysis ..............................................................................................................17 Nikos Paragios, Ecole Nationale des Ponts et Chaussees Image Interpolation Based on Optimal Mass Preserving Mappings .......................21 Lei Zhu, Allen Tannenbaum, Georgia Institute of Technology Th_PM_OS2: Advanced Methods in Ultrasound Imaging Dual-Mode Ultrasound Phased Arrays for Imaging and Therapy ..........................25 Emad Ebbini, University -
Council Resources
Council ON Library InformationAND Resources Annual Report 2007–2008 DIRECTORS , JULY 1, 2007–JUNE 30, 2008 Francis X. Blouin University of Michigan Peter Brantley Digital Library Federation Mark Dimunation Library of Congress Charles Henry Council on Library and Information Resources Michael Ann Holly Sterling and Francine Clark Art Institute Paula T. Kaufman University of Illinois at Urbana-Champaign Wendy Pradt Lougee University of Minnesota Claudia Lux Central and Regional Library of Berlin Carole Moore The Council on Library and Information Resources (CLIR) grew University of Toronto out of the 1997 merger of the Commission on Preservation and Access Stephen Nichols (CPA) and the Council on Library Resources (CLR). Over the years, CPA The Johns Hopkins University and CLR, in partnership with libraries, archives, and other information S. Georgia Nugent providers, had advocated collaborative approaches to preserving the Kenyon College nation’s intellectual heritage and strengthening the many components of its information system. CLIR was founded to continue this tradition of Herman Pabbruwe Brill support for a national information system and a seamless web of infor- mation resources, of which all libraries and archives are a part. James F. Williams, II University of Colorado at Boulder The convening role is central to CLIR’s mission. CLIR brings together Lizabeth (Betsy) Wilson experts from around the country and around the world and asks them to University of Washington turn their intelligence to the problems that libraries, archives, and infor- Karin Wittenborg mation organizations face as they integrate digital resources and services University of Virginia into their well-established print-based environments. Celia Ribeiro Zaher Fundação Biblioteca Nacional Ministério da CLIR urges individuals to look beyond the immediate challenges and Cultura, Brazil imagine the most desirable outcomes for the users of libraries and ar- chives—to be rigorously practical and to dream. -
Open Letter to Nih Director Francis Collins
OPEN LETTER TO NIH DIRECTOR FRANCIS COLLINS Francis Collins, MD, PhD Director National Institutes of Health Bethesda, MD 20892 Dear Dr. Collins: We are writing to request that NIH delay implementation of its policy that sweeps basic science into a clinical trials framework until adequate feedback about its impact is obtained from the affected scientific community. We wholeheartedly agree with NIH’s goals of increasing scientific transparency and rigor, but we ask that you consider alternative mechanisms to accomplish those goals that would have fewer adverse effects on basic research. The mission of National Institutes of Health is to fund a wide range of health-related research. Some of this research consists of clinical trials: testing the effects of interventions that could be developed into treatments for improving health. Clinical trials are the key method for establishing the efficacy, and safety, of potential new treatments. The NIH also funds, as part of its mandate, basic discovery science on health-related topics. Basic discovery science tests hypotheses about how human minds and bodies work. History shows that basic science is necessary: the discoveries made by the basic science of today provide the foundation for the clinical trials of tomorrow. New treatments can only be invented on the basis of new knowledge about how the mind and body work. The NIH’s interpretation of its definition of “clinical trials” is so broad that many experiments designed to test hypotheses about how the mind and body work will be inappropriately