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2013 Faseb Science Research Conferences Advisory Committee Meeting

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2013 Faseb Science Research Conferences Advisory Committee Meeting Proposal #: 15-05 2013 FASEB SCIENCE RESEARCH CONFERENCES ADVISORY COMMITTEE MEETING TOPIC FOR CONSIDERATION TOPIC NAME: GASTROINTESTINAL TRACT XVI. GI HOMEOSTASIS: THE MICROBIOME AND THE BARRIER, DEVELOPMENT AND DISEASE PREVIOUS TITLE: Gastrointestinal Tract XV: Epithelia, Microbes, Inflammation and Cancer SUBMITTED BY: Richard M. Peek, Jr., Vanderbilt University Medical Center Jason Mills, Washington University School of Medicine Melissa H. Wong, Oregon Health & Science University YEAR REQUESTED FOR SCHEDULING: 2015 SITE REQUESTS: 1. Steamboat Springs, CO 2. Big Sky, MT 3. Keystone, CO DATE REQUESTS: 1. August 9-14, 2015 2. August 16-21, 2015 3. August 2-7, 2015 YEAR(S) CONFERENCE HAS BEEN HELD: 1985, 1987, 1989, 1991, 1993, 1995, 1997, 1999, 2001, 2003, 2005, 2007, 2009, 2011, 2013 NOTES: To the best of our knowledge, there is not a direct conflict with any other FASEB SRC or other society or industry meeting. 2015 FASEB Summer Research Conference Proposal Gastrointestinal Tract XVI. GI homeostasis: The microbiome and the barrier, development and disease Section 2: Conference Title & Organizer Information: TITLE OF CONFERENCE: Gastrointestinal Tract XVI. GI homeostasis: The microbiome and the barrier, development and disease # of EXPECTED ATTENDEES: 160 Preferred Primary Point of Contact for Proposal Questions: Dr. Richard M. Peek, Jr. Professor of Medicine and Cancer Biology Director, Division of Gastroenterology, Hepatology and Nutrition Vanderbilt University Medical Center 2215 Garland Avenue, 1030C MRB IV Nashville, TN 37232, USA Phone: 615-322-5200 Fax: 615-343-6229 Email: [email protected] Science Categories 1) Cell Biology, 2) Developmental Biology, 3) Microbiology Organizing Committee: a) Organizer Co-Chair: Richard M Peek, Jr., MD Professor of Medicine and Cancer Biology Director, Division of Gastroenterology, Hepatology and Nutrition Vanderbilt University Medical Center 2215 Garland Avenue, 1030C MRB IV Nashville, TN 37232, USA Phone: 615-322-5200 Fax: 615-343-6229 Email: [email protected] b) Organizer Co-Chair: Jason Mills, MD/PhD Associate Professor of Medicine Associate Director, Washington University Digestive Disease Center Washington University School of Medicine 660 S. Euclid Avenue, Campus Box 8124 St. Louis, MO 63110, USA Phone: 314-362-4213 Fax: 314-632-7487 Email: [email protected] c) Organizer Co-Chair: Melissa H. Wong, PhD Associate Professor Vice Chair of Cell and Developmental Biology Oregon Health & Science University 3181 SW Sam Jackson Park Rd, Mailcode L215 Portland, OR 97239, USA Phone: 503-494-8749 Fax: 503-494-4253 Email: [email protected] Section 3: Program Submission Requirements & Outline: Overview of Program Flow # of Days: 6 # of Sessions per day: 2 # of Speaker per day: 10-18 # of Session chairs per day: 2-4 # of Breakouts per day: 1 breakout session/meeting (Meet the Experts) # of Abstracts per day: 3-4 Abbreviation Key: C = confirmed chair; CS = confirmed speaker; W = female; M = minority; NEW = new speaker or chair; ASSTP = assistant professor; *NYI = not yet invited *Note that we have opted to allow for some flexibility in the scheduling to accommodate the inclusion of invited talks that represent newly emerging science in 2013-2015. SUNDAY To include: Conference Registration 4 p.m. – 9 p.m., FASEB SRC Welcome Reception 5 p.m. – 6 p.m., Dinner 6 p.m. – 7 p.m. Title of Session: Keynote Session Chair & Affiliation: Richard Peek, Vanderbilt (C), Jason Mills, Washington University School of Medicine (C), Melissa Wong, Oregon Health & Science University (C, W) Martin Blaser, MD (CS, NEW) New York University School of Medicine Keynote: "The human microbiome: at the interface of health and disease" MONDAY To include: Group photo during morning break 1) Title of Session: Microbial Ecosystems and the GI Tract Session Chair & Affiliation: Gail Hecht, Loyola University (C, W) Speaker 1: Andrew Neish, Emory University (CS, NEW) Tentative Title of Talk: “Redox signaling and the gut microbiota” Speaker 2: Karen Guillemin, University of Oregon (CS, W, NEW) Tentative Title of Talk: “Zebrafish as a model to study bacterial-host symbiosis” Speaker 3: Lora Hooper, University of Texas-Southwestern (CS, W) Tentative Title of Talk: ”Interactions between the microbiota and the immune system” Speaker 4: Justin Sonnenburg, Stanford University (NYI, NEW, ASSTP) Tentative Title of Talk: “Bacterial consumption of host glycans and gut pathology” Speaker 5: Sarkis Mazmanian, California Institute of Technology (NYI, NEW) Tentative Title of Talk: “Disruption of the gut microbiome and microbial infections” E poster session Moderator & Affiliation: Wayne Lencer, Dana Farber/Harvard (NYI) 6 ePoster presentations selected from junior faculty and trainee abstracts Breakout session: Meet the experts Panel & Affiliation: Judy Podskalny, NIH (NYI, W), Jill Carrington, NIH (NYI, W), Michael Grey, NIH (NYI, NEW), Sean Colgan, University of Colorado (NYI) Poster session 2) Title of Session: Host and microbial mediators of disease Session Chair & Affiliation: James Casanova, University of Virginia (C) Speaker 1: Nina Salama, University of Washington (CS, W, NEW) Tentative Title of Talk: “Novel pathogenic functions for bacterial cell wall constituents” Speaker 2: Brent Polk, University of Southern California (CS, NEW) Tentative Title of Talk: “The duality of EGFR in inflammation-associated cancer” Speaker 3: Beth McCormick, University of Massachusetts (CS, W) Tentative Title of Talk: “Salmonella effector proteins and host cell responses” Speaker 4: Thad Stappenback, Washington University (NYI, NEW) Tentative Title of Talk: “Viral interactions with the host and intestinal injury” TUESDAY 3) Title of Session: Mucosal Immunity Session Chair & Affiliation: Cormac Taylor, University College Dublin (C) Speaker 1: Rodney Newberry, Washington University School of Medicine (CS, NEW) Tentative Title of Talk: “Antigen presentation across the gut epithelium” Speaker 2: Ruslan Medzhitov, Yale University (CS, NEW) Tentative Title of Talk: “Innate immunity, microbes, and the gut” Speaker 3: Richard Di Paolo, St. Louis University (CS, NEW, ASSTP) Tentative Title of Talk: “Cytokines and metaplasia in the stomach” Speaker 4: Ken Cadwell, New York University (NYI, NEW, ASSTP) Tentative Title of Talk: “Autophagy and gut microbes” Speaker 5: Gabriel Nuñez, University of Michigan (NYI, M, NEW) Tentative Title of Talk: “Nod-like and Toll-like receptors in inflammatory bowel disease” E poster session Moderator & Affiliation: Deborah Gumucio, University of Michigan (NYI, W) 6 ePoster presentations selected from junior faculty and trainee abstracts Poster session 4) Title of Session: Transport, tight junctions and barrier functions Session Chair & Affiliation: Asma Nusrat, Emory University (C, W) Speaker 1: Mark Donowitz, Johns Hopkins University (CS, NEW) Tentative Title of Talk: “Transport, barrier maintenance and pathogens” Speaker 2: Jerrold Turner, University of Chicago (CS) Tentative Title of Talk: “Cytokines, cytoskeleton, tight junctions and the barrier” Speaker 3: Mark Frey, University of Southern California (CS, NEW, ASSTP) Tentative Title of Talk: “Growth factors and epithelial barrier function” Speaker 4: Kim Barrett, University of California, San Diego (NYI, W, NEW) Tentative Title of Talk: “Transport, growth factors and diarrhea” Speaker 5: Declan McCole, University of California, Riverside (NYI, NEW, ASSTP) Tentative Title of Talk: “Regulation of barrier function by cytokines” WEDNESDAY 5) Title of Session: GI Stem Cells Session Chair & Affiliation: Susan Henning, University of North Carolina (C, W) Speaker 1: Calvin Kuo, Stanford University (CS, NEW) Tentative Title of Talk:”Intestinal stem cell hierarchy” Speaker 2: Linheng Li, Stowers (CS, NEW) Tentative Title of Talk: “Regulatory niche of the intestinal stem cell” Speaker 3: Craig Micchelli, Washington University School of Medicine (CS, NEW, ASSTP) Tentative Title of Talk: “Quiescent gastric stem cells in the Drosophila intestine” Speaker 4: Nick Barker, Institute of Medical Biology, Singapore (NYI, NEW, ASSTP) Tentative Title of Talk: “Lgr5 stem cells in regeneration and cancer” Speaker 5: Volker Harenstein, UCLA (NYI, NEW) Tentative Title of Talk: “Migration of small intestinal stem cells” 2 short presentations selected from junior faculty and trainee abstracts Group activity 1 p.m. – 5 p.m. 6) Title of Session: Dedifferentiation and reprogramming in development and cancer Session Chair & Affiliation: Linda Samuelson, University of Michigan (C, W) Speaker 1: Owen Sansom, Beatson Institute, Glasgow, Scotland (CS, NEW) Tentative Title of Talk: “Early events in intestinal neoplasia” Speaker 2: Meri Huch, University of Heidelberg, Germany (CS, W, NEW, ASSTP) Tentative Title of Talk: “Stem cell plasticity in the stomach and other GI organs” Speaker 3: Steven Leach, Johns Hopkins University (CS, NEW) Tentative Title of Talk: “Differentiation, dedifferentiation, transcription factors and pancreatic acinar cells” Speaker 4: Courtney Houchen, Oklahoma University Health Sciences Center (NYI, M) Tentative Title of Talk: “Dedifferentiation, DLSCK1 and cancer in intestine and pancreas” Speaker 5: Florian Greten, University of Frankfurt, Germany (NYI, NEW) Tentative Title of Talk: “Reprogramming of differentiated cells in cancer” THURSDAY 7) Epithelial injury, regeneration and disease Session Chair & Affiliation: Kay Lund, University of North Carolina (C, W) Speaker 1: Noah Shroyer, Baylor College of Medicine (CS) Tentative Title of Talk: ”Notch signaling regulation in
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