Honoring the Past, Shaping the Future. 75 YEARS of DISCOVERY, INNOVATION and CARE

Total Page:16

File Type:pdf, Size:1020Kb

Honoring the Past, Shaping the Future. 75 YEARS of DISCOVERY, INNOVATION and CARE Honoring the Past, Shaping the Future. 75 YEARS OF DISCOVERY, INNOVATION AND CARE Division of Gastroenterology and Hepatology UNIVERSITY OF MICHIGAN HEALTH SYSTEM Acknowledgements I would like to express my sincere gratitude to every person whose hard work and dedication to the Division has made our 75 year journey truly remarkable. Our Division today is fortunate to be enriched not only by our faculty, fellows and investigators, but by over 150 talented staff. Every individual’s contribution is invaluable and very much appreciated. Following the 75 th Anniversary Theresa Nester, Administrative Hilary Robinson, Associate Director, Celebration I received many heartfelt Specialist, Division of Michigan Creative, and the Michigan messages from guests letting me Gastroenterology and Hepatology Creative team including, Martin know how much they enjoyed Soave and Ruth Gretzinger, Lori Hirshman, Associate Director themselves at the events. I would like and also Kim Roth, from Outword of Development, Marie Marsneck, to thank the following individuals Communications Development Assistant, and Jane for their tireless efforts to ensure the Bronson, Development Events Team Sincerely, celebration was an overwhelming success. Bill Burgard, Lecturer II, Stamps School of Art and Design Jeff Holden, MBA, Division Administrator, Division of CHUNG OWYANG, MD, Gastroenterology and Hepatology Chief, Division of Gastroenterology and Hepatology © 2016 Regents of the University of Michigan Table of Contents Welcome . 3 Foundations: Our History . 5 Committed to Excellence . 27 Faculty Leadership . 28 Clinical Programs . 41 Education + Training . 88 1 Basic, Clinical + Translational Research . 102 Global Reach: Engaging with the World . 143 Recognition + Awards: Honoring the Leaders and Best . 149 Friends + Donors . 155 Poised for Growth . 163 Celebrate! . 169 Thank You . 184 Acknowledgments 2 Welcome The world was a different place 75 As you read through these pages, We’ve done great work, and we’ve years ago, when the nascent Division you’ll find the history of our Division had fun doing it. As one former of Gastroenterology and Hepatology in words and images. From the faculty member put it, “There are began. A new car cost $850, and gas earliest days of the first Division very few academic departments in was 12 cents a gallon. Thanksgiving Chief H. Marvin Pollard, who any university in the world with this had just become an official national introduced the fiberoptic endoscope, much talent, and faculty who stay in holiday. The Maltese Falcon was one to this year’s brand-new innovations harmony and love and respect each of the most popular movies and in research and clinical care, the other.” “Chattanooga Choo-Choo” one of the Division has remained true to its Here’s to the next 75 years of research most popular songs. And the massive mission of finding new solutions and discovery! presidential sculptures on Mount for clinical issues and developing 3 Rushmore were unveiled. and training the next generation of leaders. But while much has changed, some things remain constant, including our commitment to excellence in CHUNG OWYANG, MD patient care. 4 Foundations: OUR HISTORY 5 6 BASIL I. HIRSCHOWITZ, MD 7 R.J. BOLT, MD ARTHUR B. FRENCH, MD Dr. H. Marvin Pollard { Division Chief 1947 – 1972 } The Pollard Era { 1940 – 1972 } Under the leadership of DR. H. MARVIN POLLARD (MD 1931, Residency 1933), the University of focused on gastrointestinal peptides, Michigan Division of Gastroenterology was founded in the 1940s, long before the specialty the Pollard GI Research Institute was officially recognized by the American Board of Internal Medicine. Dr. Pollard attended a helped demonstrate the Division’s number of postgraduate courses, but he was not formally trained as a gastroenterologist . long history of and commitment to Still, he went on to become a renowned pancreatic cancer researcher, a visionary leader successful clinical and translational of the Division and an innovative thinker . With characteristic foresight, he laid a strong research. A grant to establish the new foundation upon which the Division would continue to grow and flourish in clinical care, center was awarded, and the Center for training and research . Gastrointestinal Research is thriving and has been continuously funded Dr. Pollard was the first to no resources available at that time first of its kind to receive National since its founding in 1984. introduce the fiberoptic to fund such programs, Dr. Pollard Institutes of Health research funding 8 endoscope, a semi-rigid undertook a fundraising effort, and career development awards. It During his tenure, Dr. Pollard trained a endoscope, into the GI personally soliciting donors. He used remains in existence today and has number of notable gastroenterologists, Division’s clinics. He the monies to help establish the first played a significant role in many who went on to become prominent believed strongly in the gastrointestinal research unit at the investigational efforts over the years inventors, clinicians and leaders importance of research to University of Michigan. as well as in attracting TADATAKA in their own right: DRS. BASIL I. fuel innovation in clinical “TACHI” YAMADA, MD, KBE, to the HIRSCHOWITZ KEITH S. HENLEY A foundation for research , , practice and that every University as Division Chief in 1983. ROBERT J. BOLT WILLIAM H. excellence , prominent academic entity BACHRACH, ARTHUR B. FRENCH, When Dr. Yamada and DR. CHUNG should devote considerable time The resulting Marvin Pollard GI LUDOVIC STANDAERT, JORGE OWYANG, current Division Chief, and effort in pursuit of basic and Research Center represented a GUMUCIO, MILTON WEISER and applied to the NIH in the early 1980s to clinical research. Since there were groundbreaking institution, the DAVID W. WATSON. support an additional research center Invention and innovation Julius Friedenwald Medal, the highest An inspiring mentor to his U-M distinction bestowed by the American colleagues and a masterful clinician One of the most important Gastroenterological Association. with patients, Dr. Pollard also President of AGA, ASGE, ACP, developments during the Pollard generously gave of his time to the American Cancer Society era was Dr. Hirschowitz’s invention An equally important achievement profession. He presided over a of the fiberoptic endoscope, the first during the Pollard era was the number of organizations including the fully flexible scope able to examine development of a simplified multiple- American Gastroenterology Association, the upper gut. Working together retrieving small-bowel biopsy tube. In the American College of Physicians and 1st with renowned fiberoptics experts 1962, Drs. Bolt and French, who both the American Cancer Society. He was Drs. Hopkins and Kapany, and trained under Dr. Pollard, performed Founder and first Division also one of the founders of the World subsequently with U-M colleagues the modern era’s first intestinal biopsy. Chief of Gastroenterology Gastroenterology Organisation and C. Wilbur Peters and undergraduate The three physicians published their (1940 – 1972) 9 served as its president. student Lawrence E. Curtiss of the invention and findings in The American Physics department, Dr. Hirschowitz Journal of Digestive Diseases (1962; The endowments in Dr. Pollard’s name completed construction of the first 7: 773). have grown over the last 30 years and 1st generation fiberscope, supported with currently fully support seven endowed Using this instrument, Drs. French resources provided by Dr. Pollard. professorships within the Division of Development of first fiberoptic and Bolt performed pioneering The invention became the prototype Gastroenterology. Dr. Pollard retired in gastroscope studies correlating morphology and for the gastroduodenal scope the 1972, after more than three decades malabsorption in celiac disease. Division now uses in its Medical leading the Division. Renowned researcher in Subsequently, Dr. French went on to Procedures Unit. For this achievement, pancreatic cancer serve as the first director of the U-M Dr. Hirschowitz was awarded the Clinical Research Unit. JORGE J. GUMUCIO, MD 10 MILTON G. MUTCHNICK, MD 11 WILLIAM O. DOBBINS III, MD STANLEY R. STRASIUS, MD Dr. Keith S. Henley { Division Chief 1972 – 1981 } The Henley Era { 1972 – 1981 } After Dr. Pollard retired in the fall of 1972, DR. KEITH S. HENLEY, a hepatologist interested in alcoholic liver disease, was appointed the second Chief of Gastroenterology . Dr . Henley quickly became known for his integrity, accessibility, scrupulous fairness and deep moral conscience . Financial pressures in the late Dr. Henley was able to attract become the U-M Liver Transplant 1960s challenged Dr. Henley budding Gl talent, including Program, one of the first in the to continue to build a current Division Chief DR. United States. The results of his community of of scholars CHUNG OWYANG; DR. TIMOTHY clinical efforts and his hepatology in gastroenterology once T. NOSTRANT; DR. JOEL V. research have had far-reaching he took over as chief. He WEINSTOCK and DR. JEANPIERRE impact on the care of liver disease devoted considerable RAUFMAN, both of whom are now and liver transplant patients. 12 effort to recruiting faculty division chiefs at other institutions; Dr. Henley led the Division until capable of obtaining NIH DR. JOHN A. SCHAFFNER, who 1981 and retired in 1993. grants in order to help enjoys a distinguished career as an rejuvenate the Division. educator at the Mayo Clinic; and DR. STANLEY
Recommended publications
  • Official Program
    OFFICIAL PROGRAM ___________________________________________________________________ Generously Sponsored by: TABLE OF CONTENTS SCHEDULE 3 KEYNOTE SPEAKERS 5 BREAKOUT SESSIONS 7 ORAL PRESENTATIONS 11 POSTER SESSION 1 (ORGANIZED BY POSTER NUMBER) 13 POSTER SESSION 2 (ORGANIZED BY POSTER NUMBER) 16 ABSTRACTS – ORAL PRESENTATIONS 19 ABSTRACTS – POSTER SESSION 1 44 ABSTRACTS – POSTER SESSION 2 91 SEMSS ORGANIZING COMMITTEE 135 LIGHT HALL & CAMPUS MAPS 136 SEMSS encourages open and honest intellectual debate as part of a welcoming and inclusive atmosphere at every conference. SEMSS asks each participant to foster rigorous analysis of all science presented or discussed in a manner respectful to all conferees. To help maintain an open and respectful community of scientists, SEMSS does not tolerate illegal or inappropriate behavior at any conference site, including violations of applicable laws pertaining to sale or consumption of alcohol, destruction of property, or harassment of any kind, including sexual harassment. SEMSS condemns inappropriate or suggestive acts or comments that demean another person by reason of his or her gender, gender identity or expression, race, religion, ethnicity, age or disability or that are unwelcome or offensive to other members of the community or their guests. * *Adapted from the language of Gordon Research Conferences 2 SEMSS 2018 SCHEDULE SATURDAY, NOVEMEBER 10, 2018 _____________________________________________________________________________________ REGISTRATION 12:30 – 1:00 PM Location: Light Hall, North
    [Show full text]
  • 2013 Faseb Science Research Conferences Advisory Committee Meeting
    Proposal #: 15-05 2013 FASEB SCIENCE RESEARCH CONFERENCES ADVISORY COMMITTEE MEETING TOPIC FOR CONSIDERATION TOPIC NAME: GASTROINTESTINAL TRACT XVI. GI HOMEOSTASIS: THE MICROBIOME AND THE BARRIER, DEVELOPMENT AND DISEASE PREVIOUS TITLE: Gastrointestinal Tract XV: Epithelia, Microbes, Inflammation and Cancer SUBMITTED BY: Richard M. Peek, Jr., Vanderbilt University Medical Center Jason Mills, Washington University School of Medicine Melissa H. Wong, Oregon Health & Science University YEAR REQUESTED FOR SCHEDULING: 2015 SITE REQUESTS: 1. Steamboat Springs, CO 2. Big Sky, MT 3. Keystone, CO DATE REQUESTS: 1. August 9-14, 2015 2. August 16-21, 2015 3. August 2-7, 2015 YEAR(S) CONFERENCE HAS BEEN HELD: 1985, 1987, 1989, 1991, 1993, 1995, 1997, 1999, 2001, 2003, 2005, 2007, 2009, 2011, 2013 NOTES: To the best of our knowledge, there is not a direct conflict with any other FASEB SRC or other society or industry meeting. 2015 FASEB Summer Research Conference Proposal Gastrointestinal Tract XVI. GI homeostasis: The microbiome and the barrier, development and disease Section 2: Conference Title & Organizer Information: TITLE OF CONFERENCE: Gastrointestinal Tract XVI. GI homeostasis: The microbiome and the barrier, development and disease # of EXPECTED ATTENDEES: 160 Preferred Primary Point of Contact for Proposal Questions: Dr. Richard M. Peek, Jr. Professor of Medicine and Cancer Biology Director, Division of Gastroenterology, Hepatology and Nutrition Vanderbilt University Medical Center 2215 Garland Avenue, 1030C MRB IV Nashville, TN 37232, USA
    [Show full text]
  • Chicago 2013 Final Program
    CHICAGO 2013 FINAL PROGRAM 2013 Combined Annual Meeting of Central Society for Clinical and Translational Research and Midwestern Section American Federation for Medical Research Renaissance Blackstone Chicago CHICAGO, IL • APRIL 25-26, 2013 Jointly prese nted by CS CTR, M WAF MR a nd I nstit ute for t he A dvan ceme nt of Huma n Behav ior (IAHB) Central Society for Clinical and Translational Research 555 East Wells Street Suite 1100 Milwaukee, WI 53202 Phone 414.273.2209 Fax 414.276.3349 Web www.CSCR.com Midwestern Section American Federation for Medical Research 500 Cummings Center - Suite 4550 Beverly, MA 01915 Phone 978.927.8330 Fax 978.524.8890 Web www.afmr.org 2013 Combined Annual Meeting Learning Objectives This activity has been planned and implemented in accordance The 2013 Combined Annual Meeting of the Central Society with the Essential Areas and Policies of the Accreditation for Clinical and Translational Research (CSCTR) and the Council for Continuing Medical Education through the Midwestern Section American Federation for Medical Research joint sponsorship of the Institute for the Advancement of (MWAFMR) presents the Hickam Lecture, Keynote Speaker, Human Behavior (IAHB) and Central Society for Clinical and two plenary sessions and an oral abstract session on topics Translational Research and American Federation for Medical of timely interest for researchers and physicians interested in Research. [IAHB] is accredited by the ACCME to provide the broad field of clinical research. Participants at the 2013 continuing medical education for physicians. Combined Annual Meeting will acquire knowledge into clinical Credit Designation Statement research techniques and new findings in various aspects of internal medicine and other fields.
    [Show full text]
  • What Is Function?
    What is Function? From organelles to organisms, Function seeks papers that contribute to defining the mechanistic basis of living systems in health and disease. Function aims to be a highly selective journal, publishing major advances that extend physiological understanding of biological function and the changes associated with disease states. Why Function? Why Now? The American Physiological Society (APS) developed Function to provide a new home for authors—members and nonmembers—who welcome a fresh, multidisciplinary option for publishing their most important physiology research. What Makes Function Unique? Function will be unique as an open access, high-profile physiology journal that is society-owned and edited by working scientists. New features have been added to expediate the publication of the most important physiology research. New Features FUNCTION FOCUS PERSPECTIVE ARTICLES This new type of short focus article reports For full original research articles, Function on a new and important observation. These will include a perspective, opinion, or “quick release” articles allow for solid research commentary article from a top expert in the to be reported without all the ramifications field providing an elevated point of view on expected in a full research paper. the scientific impact of the article. NEW STYLE EVIDENCE REVIEWS FINAL DECISION AFTER INITIAL REVIEW These articles will evaluate the factual Submitting authors will receive a firm new style evidence in a field and therefore only cite decision about acceptance or rejection after original articles and not other reviews. the initial review, even if revisions are needed. Learn more and submit at journals.physiology.org/function. Questions? Contact [email protected].
    [Show full text]
  • Stomach Cancer Symposium
    SPOTLIGHT ON Stomach Cancer Symposium Saturday, October 26th 2019 8:00 AM – 2:20 PM The Spotlight on Stomach Cancer ™ is an opportunity for those in the stomach cancer community, the medical community, and the general public to come together to learn more about stomach cancer and connect with others impacted by this disease. AGENDA 8:00 – 8:30 11:35 – 12:10 Continental Breakfast Lunch Health Sciences Innovation Bldg (HSIB) Location: HSIB Atrium 8:30 – 8:45 Session 3 - Multi -Disciplinary Treatment Welcome and Opening Remarks Approaches - HSIB Dylan Davison – Board Chair Moderator: Rachna Shroff, MD, MS Session 1 - Infectious Causes in Vulnerable 12:15 – 12:35 Populations - HSIB Systemic Therapy for Advanced Gastric Cancer Moderator: Robin Harris, MPH, PhD Aaron Scott, MD GI Medical Oncology 8:45 – 9:05 Associate Professor of Medicine H. pylori and Gastric Cancer in South Texas University of Arizona Cancer Center Hispanic Populations Dorothy Long Parma, MD, MPH 12:35 – 12:55 Institute for Health Promotion Research (IHPR), Non-Surgical Treatment in Early Gastric Cancer Department of Population Health Sciences at UTHealth Hemanth Gavini, MD, MPH San Antonio (UTHSA) School of Medicine. Medical Director of Endoscopy Assistant Professor, Gastroenterology & Hepatology, 9:10 – 9:30 University of Arizona H. pylori and Gastric Cancer in Native Americans Gregory Jarrin, MD, FACS 12:55 – 1:15 Winslow Indian Health Care Center Inc. Questions & Answers Panel Discussion 9:30 – 9:50 Patient Perspectives 1:15 – 1:25 Katherine Smith Refreshment Break Guest Speaker Navajo Tribe, Flagstaff, AZ Session 4 - Healthy Living without a Stomach Moderator: Aaron Scott, MD 9:50 – 10:05 Questions & Answers 1:25 – 1:40 Panel Discussion Patient Perspectives Lionel Corral 10:05 – 10:25 Guest Speaker Refreshment Break Tucson, AZ Atanasio Gastzionis and Thano Gatzionis Session 2 - Impact of the Genome on Risk, Guest Speakers Diagnosis and Family - HSIB Nogales, AZ Moderator: Juanita L.
    [Show full text]
  • Internal Medicine
    internal medicine 2 O 1 1 A N N U A L R E PO RT TABLE O F CO NTENTS Chair’s Report 2 Clinical Programs 4 Faculty Affairs 6 Veterans Affairs 8 Basic & Translational Research 10 Clinical Research 12 Graduate Medical Education 14 Patient Care 20 Research 38 Education 56 Outreach 62 Department Updates 73 Chair’s REPO RT John Carethers, MD Chair CONTINUED RECOGNITION When U.S. News & World Report recently released their rankings of medical schools and medical school specialties, the U-M Department of Internal Medicine was ranked 6th overall nationally, tying our rank for last year, and a repeat of our highest rank in more than 10 years. U-M’s Medical School tied for 10th overall for research medical schools, and 8th overall for primary care medical schools. This recognition by our peers and others is a testament to our efforts to make U-M the best place for education and training, for clinical care, and for research. This past year, 2011, was no exception. Some of our most notable efforts included: MAKING U-M A DESTINATION leadership and extensive research efforts related to Our 2011 annual report’s theme is “Destination Internal metabolic diseases such as obesity (page 40). Medicine.” I wanted to feature our department’s participation in numerous Destination Programs, or RESEARCH GROWTH Centers of Excellence, that are being highlighted by Our research funding and efforts are still going the U-M Health System. These amazing multi- strong. Some of our research groups have moved or disciplinary programs are bringing the best of U-M’s are planning to move to U-M’s North Campus research and clinical care expertise together to create Research Complex to take advantage of NCRC’s the ideal patient experience (page 22).
    [Show full text]
  • The GI Digest Department of Internal Medicine, Division of Gastroenterology and Hepatology
    the GI Digest Department of Internal Medicine, Division of Gastroenterology and Hepatology Spring 2017 • Volume 12 • Issue 1 Faculty and Fellows in the News at DDW 2017 Chief Observations The DDW 2017 Issue Michigan Medicine Gastroenterology and Hepatology Chief Observations 1 faculty, fellows, research scientists and mid-level providers Past, Present and Future 2 will converge at Digestive Disease Week in Chicago, IL from Dr. Carethers 3 May 6–9, 2017. Recognized as one of the top 50 medical meetings by HCEA, Digestive Disease Week® is the world’s Dr. Conjeevaram 4 largest gathering of physicians, researchers and industry Dr. Merchant 5 working in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery. DDW provides an DDW Awards and Recognition 6 unparalleled opportunity for our Division to showcase to Distinguished Abstract and Presidential our peers throughout the world the many accomplishments Plenary Sessions 8 we have achieved over the past year. Our strong tradition of Moderators 9 leadership and recognition at DDW continues this year. Research and Topic Forums 11 I am proud to announce that three of our faculty will receive prestigious AGA awards: Dr. John Carethers will receive the AGA Distinguished Mentor Award, Symposia 15 Dr. Hari Conjeevaram, the AGA Distinguished Educator Award, and Dr. Juanita AGA and ASGE Postgraduate Courses Merchant, the Distinguished Achievement Award in Basic Science. Dr. Shrinivas Breakfast with the Expert, Poster Tours 17 Bishu will receive the 2017 AGA–Pfizer Pilot Research Award in Inflammatory Daily Schedule 18 Bowel Disease. We are also very proud of the many division faculty serving in leadership roles to organize this year’s DDW program.
    [Show full text]
  • APPENDIX 2: Rosters of the National Commission on Digestive Diseases and Its Working Groups
    APPENDIX 2: Rosters of the National Commission on Digestive Diseases and Its Working Groups Chairperson Executive Director Stephen P. James, MD Robert D. Hammond, PhD Director Robert D. Hammond Associates, LLC Division of Digestive Diseases and Nutrition National Institute of Diabetes and Digestive and Kidney Diseases National Institutes of Health Appointed Commission Members Bruce R. Bacon, MD Mitchell B. Cohen, MD Director Director Division of Gastroenterology & Hepatology Division of Gastroenterology, Hepatology & Nutrition St. Louis University School of Medicine Cincinnati Children’s Hospital Medical Center Barbara L. Bass, MD, FACS Margaret M. Heitkemper, RN, PhD John F. & Carolyn Bookout Distinguished Chairperson Endowed Chair Department of Biobehavioral Nursing & Health Systems Department of Surgery University of Washington The Methodist Hospital Jane M. Holt Richard S. Blumberg, MD Co-President Professor of Medicine and Chief National Pancreas Foundation Gastroenterology Division David A. Lieberman, MD Brigham and Women’s Hospital Professor and Chief John M. Carethers, MD Division of Gastroenterology Professor of Medicine Department of Medicine Chief, Division of Gastroenterology Oregon Health and Science University University of California, San Diego Nancy J. Norton, BS Maurice A. Cerulli, MD Founder and President Chief International Foundation for Functional Division of Gastroenterology & Hepatology Gastrointestinal Disorders New York Methodist Hospital Pankaj J. Pasricha, MD Eugene B. Chang, MD Professor of Medicine Martin
    [Show full text]
  • Complete Research Plan
    Illustration of the human digestive system: Image reprinted from “Your Digestive System and How It Works.” U.S. Department of Health and Human Services. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases. NIH Publication No. 08-2681, April 2008. Inset images: Top image and third image down—Richard Nowitz for NIDDK; second image down— Used with permission of the NIDDK Weight-Control Information Network; Bottom image—Randy Faris/Corbis. Opportunities and Challenges in Digestive Diseases Research: Recommendations of the National Commission on Digestive Diseases U.S. Department of Health and Human Services National Institutes of Health NIH Publication No. 08-6514 March 2009 TABLE OF CONTENTS EXECUTIVE SUMMARY 1 INTRODUCTION 13 TOPIC-SPECIFIC CHAPTERS Research on the Basic Biology of the Digestive System 25 Functional Gastrointestinal Disorders and Motility Disorders 51 Infections of the Gastrointestinal Tract 69 Cancers of the Digestive System 81 Inflammatory Bowel Diseases 95 Intestinal Failure and Regeneration, Nutritional Disorders and Support, Surgically Modified Gut, and Transplantation 107 Diseases of the Oropharynx and Esophagus 117 Diseases of the Stomach and Small Intestine 129 Diseases of the Colon and Rectum 145 Diseases of the Pancreas 159 Diseases of the Liver and Biliary System 169 Bioengineering, Biotechnology, and Imaging 187 CONCLUSION: COMMON TheMes AND STeps FOR IMPLEMENTATION 195 APPENDICES Appendix 1: Summary List of Recommended Research Goals and Common Themes 207 Appendix 2: Rosters of the National Commission on Digestive Diseases and Its 214 Working Groups Appendix 3: References for Statistical and Epidemiologic Data 220 Appendix 4: Abbreviations and Acronyms 221 INDEX 226 ACKNOWLEDGEMENTS 238 Opportunities and Challenges in Digestive Diseases Research: Recommendations of the National Commission on Digestive Diseases Executive Summary BURDEN OF DIGesTIVE DIseAses IN Health and Human Services, and Education, The UNITED STATes and Related Agencies.
    [Show full text]
  • Gastroenterology by Recog- Nopathy and Vascular Architecture Is Maintained
    mdedge.com/gihepnews September 2019 Volume 13 / Number 9 Test could inform INSIDE FROM THE AGA JOURNALS care of patients with Inflammation in NAFLD pancreatic cysts It reduces quality of life, not fibrosis. • 12 BY JENNIFER SMITH those who need no addi- MDedge News tional care. AGA PRESIDENTIAL . Simeon Springer, PhD, PLENARY EIRING newly developed of Ring Therapeutics in M test could help Cambridge, Mass., and GI’s stars present clinicians more colleagues described the essential information UZANNE S A . Get the details. • 22 R accurately identify which development and testing D patients with pancreatic of CompCyst in Science cysts require surgery, ac- Translational Medicine. AGA POSTGRADUATE OURTESY C cording to researchers. The researchers collect- Dr. Annieke C.G. van Baar found that endoscopic duodenal mucosal The test, CompCyst, ed data from 875 patients COURSE SUMMARIES resection improved glycemia in patients with type 2 diabetes. incorporates clinical and who had undergone Moderators imaging data as well surgical resection of pan- summarize DDW® as data on genetic and creatic cysts. The team sessions Endoscopic duodenal biochemical markers as- used clinical, imaging, Read news from GI’s sociated with pancreatic and molecular data from subspecialties. • 27 cancer. 436 of those patients to mucosal resection CompCyst proved more train CompCyst to clas- effective than standard sify patients into three AGA GUIDELINE practice in estimating categories. Diagnosis of watery found effective in T2D the risk of cancer so as • Patients with benign, diarrhea to differentiate patients nonmucin-producing It’s important to rule out BY DOUG BRUNK crease in liver transaminase who should undergo sur- cysts who do not require things first.
    [Show full text]
  • Above the Huron
    Summer 2002 A PUBLICATION OF THE UNIVERSITY OF MICHIGAN MEDICAL SCHOOL ABOVE TH Above the Huron Until recently, scientists believed brains and hope they do what you The the mammalian adult central want them to do,” Parent says. nervous system — the brain and “There can be harmful conse- Self-Healing spinal cord — was incapable of quences.” generating new neurons from Parent’s research is supported by adult stem cells, a process known niversity of Michigan neurol- the National Institute for Neuro- Brain? ogist Jack M. Parent, M.D., is as neurogenesis. But now scien- U logical Disorders and Stroke of tists know that precursor cells in fascinated by how primitive neural the National Institutes of Health a part of the brain called the sub- cells called neuroblasts respond to and the Parents Against Child- ventricular zone or SVZ continue acute brain injuries. In a series of hood Epilepsy Foundation. His to produce new neurons through- experiments with laboratory rats, research collaborators include out life for the brain’s olfactory Parent found that neuroblasts Daniel Lowenstein, M.D., from multiply and form neural chains bulb, which processes scent. Photo: Marcia Ledford Harvard Medical School and Another area of the brain called that move across the brain to the Donna Ferriero, M.D., and Zinaida the dentate gyrus also generates injury site in an attempt to form Vexler, Ph.D., of the University of neuroblasts, which form neurons new neurons. Understanding how California-San Francisco Medical in the hippocampus — the section this self-repair mechanism works School. could someday help physicians of the brain involved in learning, reduce brain damage from strokes memory and regulating emotions.
    [Show full text]
  • March 2020 Volume 14 / Number 3
    mdedge.com/gihepnews March 2020 Volume 14 / Number 3 INSIDE GALAD score FROM THE AGA JOURNALS predicts USMSTF publishes polypectomy guidance Recommendations aim to NASH-HCC improve complete endoscopic resection More than a year in advance rates. • 6 ENTER C BY WILL PASS sensitivity of ultrasound, Task force on CRC MDedge News reported lead author Jan EDICAL updates colonoscopy M Best, MD, of the University follow-up guidance INAI or patients with Hospital Magdeburg (Ger- -S Few, small adenomas can nonalcoholic steato- many), and colleagues. be treated like none. • 7 EDARS C Fhepatitis (NASH), the “The limitations of ul- Dr. Gil Y. Melmed reported on a quality improvement initiative that GALAD score may accu- trasound surveillance LIVER DISEASE also reduced hospitalizations and opioid use. rately predict hepatocel- alone for early detection Serum keratin 18 lular carcinoma (HCC) as of HCC are particularly early as 560 days before evident in patients with shows injury in AAH IBD quality initiative diagnosis, according to in- NASH,” the investigators Biomarker outperforms vestigators. wrote in Clinical Gastroen- MELD, other measures. The GALAD score, terology and Hepatology. • 18 slashes ED utilization which combines sex, age, “Serum-based biomarkers PRACTICE alpha-fetoprotein-L3 might be more effective, BY RICHARD MARK KIRKNER ment visit rates decline from (AFP-L3), alpha-fetopro- with or without ultra- MANAGEMENT MDedge News 18% to 14%, a 22% relative tein, and des-gamma-car- sound surveillance, for Toolbox: E/M changes decrease, Gil Y. Melmed, MD, boxyprothrombin (DCP), HCC surveillance in NASH coming for 2021 REPORTING FROM CROHN’S & COLITIS CONGRESS AGAF, of Cedars-Sinai Medi- could improve cancer sur- patients, although data in AGA outlines the coding cal Center, Los Angeles, said.
    [Show full text]