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Tools for Optimising Pharmacotherapy in Psychiatry (Therapeutic Drug Monitoring, Molecular Brain Imaging and Pharmacogenetic Tests) Focus on Antidepressants Eap, C University of Southern Denmark Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests) focus on antidepressants Eap, C. B.; Gründer, G.; Baumann, P.; Ansermot, N.; Conca, A.; Corruble, E.; Crettol, S.; Dahl, M. L.; de Leon, J.; Greiner, C.; Howes, O.; Kim, E.; Lanzenberger, R.; Meyer, J. H.; Moessner, R.; Mulder, H.; Müller, D. J.; Reis, M.; Riederer, P.; Ruhe, H. G.; Spigset, O.; Spina, E.; Stegman, B.; Steimer, W.; Stingl, J.; Suzen, S.; Uchida, H.; Unterecker, S.; Vandenberghe, F.; Hiemke, C. Published in: World Journal of Biological Psychiatry DOI: 10.1080/15622975.2021.1878427 Publication date: 2021 Document version: Final published version Document license: CC BY-NC-ND Citation for pulished version (APA): Eap, C. B., Gründer, G., Baumann, P., Ansermot, N., Conca, A., Corruble, E., Crettol, S., Dahl, M. L., de Leon, J., Greiner, C., Howes, O., Kim, E., Lanzenberger, R., Meyer, J. H., Moessner, R., Mulder, H., Müller, D. J., Reis, M., Riederer, P., ... Hiemke, C. (2021). Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests): focus on antidepressants. World Journal of Biological Psychiatry. https://doi.org/10.1080/15622975.2021.1878427 Go to publication entry in University of Southern Denmark's Research Portal Terms of use This work is brought to you by the University of Southern Denmark. Unless otherwise specified it has been shared according to the terms for self-archiving. If no other license is stated, these terms apply: • You may download this work for personal use only. • You may not further distribute the material or use it for any profit-making activity or commercial gain • You may freely distribute the URL identifying this open access version If you believe that this document breaches copyright please contact us providing details and we will investigate your claim. Please direct all enquiries to [email protected] Download date: 27. Sep. 2021 The World Journal of Biological Psychiatry ISSN: (Print) (Online) Journal homepage: https://www.tandfonline.com/loi/iwbp20 Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests): focus on antidepressants C. B. Eap, G. Gründer, P. Baumann, N. Ansermot, A. Conca, E. Corruble, S. Crettol, M. L. Dahl, J. de Leon, C. Greiner, O. Howes, E. Kim, R. Lanzenberger, J. H. Meyer, R. Moessner, H. Mulder, D. J. Müller, M. Reis, P. Riederer, H. G. Ruhe, O. Spigset, E. Spina, B. Stegman, W. Steimer, J. Stingl, S. Suzen, H. Uchida, S. Unterecker, F. Vandenberghe & C. Hiemke To cite this article: C. B. Eap, G. Gründer, P. Baumann, N. Ansermot, A. Conca, E. Corruble, S. Crettol, M. L. Dahl, J. de Leon, C. Greiner, O. Howes, E. Kim, R. Lanzenberger, J. H. Meyer, R. Moessner, H. Mulder, D. J. Müller, M. Reis, P. Riederer, H. G. Ruhe, O. Spigset, E. Spina, B. Stegman, W. Steimer, J. Stingl, S. Suzen, H. Uchida, S. Unterecker, F. Vandenberghe & C. Hiemke (2021): Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests): focus on antidepressants, The World Journal of Biological Psychiatry, DOI: 10.1080/15622975.2021.1878427 To link to this article: https://doi.org/10.1080/15622975.2021.1878427 © 2021 The Author(s). Published by Informa Published online: 12 May 2021. UK Limited, trading as Taylor & Francis Group. Submit your article to this journal Article views: 633 View related articles View Crossmark data Full Terms & Conditions of access and use can be found at https://www.tandfonline.com/action/journalInformation?journalCode=iwbp20 THE WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY https://doi.org/10.1080/15622975.2021.1878427 REVIEW ARTICLE Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests): focus on antidepressants a,b,c,d,eà fà g a h,i j,k C. B. Eap ,G.Grunder€ , P. Baumann , N. Ansermot , A. Conca , E. Corruble , S. Crettola , M. L. Dahll, J. de Leonm , C. Greinern, O. Howeso, E. Kimp,q, R. Lanzenbergerr , J. H. Meyers, R. Moessnert, H. Mulderu,v,w,x,D.J.Muller€ y,z,aa, M. Reisab,ac, P. Riedererad,ae, H. G. Ruheaf,ag , O. Spigsetah,ai, E. Spinaaj , B. Stegmanak, W. Steimeral, J. Stinglam, S. Suzenan, H. Uchidaao, S. Untereckerap, F. Vandenberghea and C. Hiemkeaq aUnit of Pharmacogenetics and Clinical Psychopharmacology, Center for Psychiatric Neurosciences, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland; bCenter for Research and Innovation in Clinical Pharmaceutical Sciences, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland; cSchool of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland; dInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Geneva, Switzerland; eInstitute of Pharmaceutical Sciences of Western Switzerland, University of Lausanne, Switzerland, Geneva, Switzerland; fDepartment of Molecular Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany; gDepartment of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland; hDepartment of Psychiatry, Health Service District Bolzano, Bolzano, Italy; iDepartment of Child and Adolescent Psychiatry, South Tyrolean Regional Health Service, Bolzano, Italy; jINSERM CESP, Team MOODS, Service Hospitalo-Universitaire de Psychiatrie, Universite Paris Saclay, Le Kremlin Bicetre, France; kService Hospitalo-Universitaire de Psychiatrie, Hopital^ Bic^etre, Assistance Publique Hopitaux^ de Paris, Le Kremlin Bic^etre, France; lDivision of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden; mEastern State Hospital, University of Kentucky Mental Health Research Center, Lexington, KY, USA; nBundesinstitut fur€ Arzneimittel und Medizinprodukte, Bonn, Germany; oKing’s College London and MRC London Institute of Medical Sciences (LMS)-Imperial College, London, UK; pDepartment of Brain and Cognitive Sciences, Seoul National University College of Natural Sciences, Seoul, South Korea; qDepartment of Psychiatry, Seoul National University College of Medicine, Seoul, South Korea; rDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria; sCampbell Family Mental Health Research Institute, CAMH and Department of Psychiatry, University of Toronto, Toronto, Canada; tDepartment of Psychiatry and Psychotherapy, University of Tubingen,€ Tubingen,€ Germany; uDepartment of Clinical Pharmacy, Wilhelmina Hospital Assen, Assen, The Netherlands; vGGZ Drenthe Mental Health Services Drenthe, Assen, The Netherlands; wDepartment of Pharmacotherapy, Epidemiology and Economics, Department of Pharmacy and Pharmaceutical Sciences, University of Groningen, Groningen, The Netherlands; xDepartment of Psychiatry, Interdisciplinary Centre for Psychopathology and Emotion Regulation, University of Groningen, Groningen, The Netherlands; yCampbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada; zDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada; aaDepartment of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada; abDepartment of Biomedical and Clinical Sciences, Linkoping€ University, Linkoping,€ Sweden; acClinical Chemistry and Pharmacology, Skåne University Hospital, Lund, Sweden; adCenter of Mental Health, Clinic and Policlinic for Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wurzburg,€ Wurzburg,€ Germany; aeDepartment of Psychiatry, University of Southern Denmark Odense, Odense, Denmark; afDepartment of Psychiatry, Radboudumc, Nijmegen, the Netherlands; agDonders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, Netherlands; ahDepartment of Clinical Pharmacology, St. Olav University Hospital, Trondheim, Norway; aiDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway; ajDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy; akInstitut fur€ Pharmazie der Universit€at Regensburg, Regensburg, Germany; alInstitute for Clinical Chemistry and Pathobiochemistry, Technical University of Munich, Munich, Germany; amInstitute for Clinical Pharmacology, University Hospital of RWTH Aachen, Germany; anDepartment of Toxicology, Faculty of Pharmacy, Ankara University, Ankara, Turkey; aoDepartment of Neuropsychiatry, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan; apDepartment of Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Wurzburg,€ Wurzburg,€ Germany; aqDepartment of Psychiatry and Psychotherapy, University Medical Center Mainz, Mainz, Germany CONTACT CB Eap [email protected] Unit of Pharmacogenetics and Clinical Psychopharmacology, Center for Psychiatric Neurosciences, Lausanne University Hospital and University of Lausanne, Hospital of Cery, Prilly-Lausanne, Switzerland; G Grunder€ [email protected] Department of Molecular Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany; C Hiemke [email protected] Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Mainz, Germany à Joint first authorship ß 2021 The Author(s). 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