Supplemental Figure
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● Agonist ● Antagonist ● Interference AR AUC 0.0 0.2 0.4 0.6 0.8 1.0 1.2 1.4 1.6 17beta−Trenbolone 5alpha−Dihydrotestosterone 17−Methyltestosterone Testosterone propionate Norethindrone Norgestrel GSK232420A 4−Androstene−3,17−dione Progesterone 17beta−Estradiol Mifepristone 17alpha−Ethinylestradiol Hydroxyflutamide 17alpha−Hydroxyprogesterone Corticosterone Nilutamide Basic Blue 7 Triphenyltin hydroxide Bicalutamide Tributyltin benzoate 17alpha−Estradiol Gentian Violet Equilin Zinc pyrithione Triticonazole Fenitrothion Mestranol Tributyltin methacrylate 2,2−Bis(4−hydroxyphenyl)−1,1,1 Dibutyltin dichloride Flutamide Methyltrioctylammonium chlorid Rhodamine 6G Tributyltetradecylphosphonium Emamectin benzoate Phenylmercuric acetate Cyproterone acetate Chlorothalonil 9−Phenanthrol 2,2',4,4'−Tetrahydroxybenzophe Melengestrol acetate Dehydroepiandrosterone 1−Chloro−2,4−dinitrobenzene SSR240612 Methylbenzethonium chloride Vinclozolin Tetraconazole Ziram Didecyldimethylammonium chlori Econazole nitrate Myristyltrimethylammonium chlo Clorophene Abamectin Octyl gallate 2−Chloro−4−phenylphenol Bisphenol A Propanil Dexamethasone sodium phosphate meso−Hexestrol Dichlorophen Hydroxyprogesterone caproate SSR241586 Bisphenol AF Prednisone Dichlone Reserpine Chlorobenzilate Diethylstilbestrol 3−Hydroxyfluorene Procymidone 4−Cumylphenol 4−Hydroxytamoxifen Napropamide PharmaGSID_48519 Clomiphene citrate (1:1) Chlorhexidine diacetate Tebuconazole Imazalil Dinocap PharmaGSID_48513 Linuron Prochloraz Zoxamide TDCPP Captan 3,3'−Dimethoxybenzidine dihydr 4−Phenylphenol Captafol Estrone Tetrabutyltin SB236057A Triclosan PharmaGSID_48510 Milbemectin (mixture of 70% Mi Ipconazole Kepone GSK163929B Dodecyltrimethylammonium chlor Bisphenol B p,p'−DDE 2,2'−(Tetradecylimino)diethano Benzalkonium chloride Diazolidinyl urea Flusilazole Bromuconazole PD 0343701 4,4',4"−Ethane−1,1,1−triyltrip Methylene blue Dimethomorph Hydramethylnon 2,2'−Methylenebis(4−methyl−6−t Bromophenol blue Hexadecyltrimethylammonium bro Hexaconazole 4−(1,1,3,3−Tetramethylbutyl)ph 4−Nonylphenol, branched Tributyltin chloride Nordihydroguaiaretic acid PharmaGSID_47315 SSR126768 Raloxifene hydrochloride 2,2'−Methylenebis(ethyl−6−tert Cycloheximide Fenhexamid 4,4'−Sulfonylbis[2−(prop−2−en− Metconazole Triflumizole Acibenzolar−S−methyl FD&C Green No. 3 2,4−Dihydroxybenzophenone Farglitazar Estriol 1,4−Dihydroxy−2−naphthoic acid Rotenone Ketoconazole Chlorophacinone 1−Phenyl−1H−pyrrole−2,5−dione Dodecylphenol SAR102779 4−Dodecylphenol Polyoxyethylene(10)nonylphenyl Tris(2,3−dibromopropyl) phosph Octhilinone Fluorescein Spironolactone Amiodarone hydrochloride Propargite Triamcinolone Diniconazole 6−Hydroxy−2−naphthyl disulfide PharmaGSID_48506 Dodecyl gallate SSR504734 Azinphos−methyl AVE6324 Phenolphthalein Methyl linoleate 2−Amino−5−azotoluene Prallethrin Eosin SAR150640 Propiconazole 2,4−Bis(1−methyl−1−phenylethyl Difenoconazole MK−968 Oxazepam Bromocriptine mesylate Apigenin Fluazinam 4−Nitrosodiphenylamine Methyl parathion 3,3'−Dimethylbenzidine dihydro 1,2−Dibromo−2,4−dicyanobutane o,p'−DDT 7,12−Dimethylbenz(a)anthracene CP−122721 Resmethrin 2−Ethylhexylparaben (2−Nitro−1−propenyl)benzene Darbufelone mesylate Dodecyl sulfate triethanolamin Tannic acid Parathion Oryzalin PharmaGSID_48505 1−Hydroxypyrene CP−607366 Butachlor Folpet 2−Chloro−N−phenylacetamide FR150011 Acetochlor Nitrofen UK−373911 Fenbuconazole Monotridecyl phosphate 4−Hexylresorcinol Disulfiram Fenthion Docusate sodium 1,2−Benzisothiazolin−3−one Clomazone Elzasonan 5HPP−33 Fabesetron hydrochloride Fandosentan potassium salt AVE5638 4,5−Dichloro−3H−1,2−dithiol−3− 3−Iodo−2−propynyl−N−butylcarba Chlorfenapyr S−Bioallethrin Alachlor Laurocapram 3,3'−Dimethylbenzidine FD&C Blue No. 1 Prodiamine Polyoxyethylene monoleate 3,3',5,5'−Tetrabromobisphenol Methylene bis(thiocyanate) PharmaGSID_48511 Fulvestrant Fluoranthene MK−274 p,p'−DDD Fenpyroximate (Z,E) Dicloran Endothal Chlordane 4,5−Dichloro−2−octyl−3(2H)−iso MGK−264 Chlorpromazine hydrochloride SSR103800 Ergocalciferol 7−(Dimethylamino)−4−methylcoum Auramine hydrochloride Disodium 4,4'−bis(2−sulfostyry Diallyl phthalate SAR115740 Michler's ketone o,p'−DDD 2−(8−Heptadecenyl)−2−imidazoli Etoxazole Pendimethalin Dicofol SR271425 Bisphenol F Allethrin Fenoxycarb Disiquonium chloride Temephos Tebufenpyrad Dicyclohexyl phthalate Carbosulfan Celecoxib Endosulfan Thiram (2R,6S)−Fenpropimorph Benzyl−C8−18−alkyldimethylammo 4−(Hexyloxy)phenol C.I. Direct Yellow 12 Clotrimazole Tamoxifen citrate 3,9−Epoxy−3H−azirino[2,3−c][1] UK−337312 3,3'−Dimethoxybenzidine Diphenylmercury(II) SR146131 Propachlor Hexachlorocyclopentadiene 1,2−Dinitrobenzene 4,4'−Dithiodimorpholine 4,4'−Methylenebis(2−methylanil Calcium dodecylbenzene sulfona Ethyl (2E,4Z)−deca−2,4−dienoat Chlorpropham Mercuric chloride Nelivaptan Lovastatin Retinol acetate Cyhalofop−butyl p,p'−DDT CP−100829 Isopropalin Fipronil SR125047 Dimethyltin dichloride Apomorphine hydrochloride hydr Bis(2−ethylhexyl) phosphate Heptachlor epoxide 4,4'−Methylenebis(2,6−diethyla PK 11195 Azoxystrobin 1,3−Diphenylguanidine Retinol Tiratricol Chlorpyrifos oxon Pyridaben Fenofibrate Glutaraldehyde Surinabant Buprofezin Mancozeb Silwet L77 4−Cyclohexylcyclohexanol Bensulide 1,2−Benzenedicarboxaldehyde Tris(2−ethylhexyl) phosphate Dazomet Tetramethrin 2,4−Di−tert−butylphenol 4−Nonylphenol Atorvastatin calcium 1,2,5,6,9,10−Hexabromocyclodod 1−Decanamine Fenarimol Triphenylethylene Methoxychlor Heptachlor Dinoseb PharmaGSID_47337 Rhodamine B Tamoxifen Dieldrin 2,5−Di−tert−butylbenzene−1,4−d Farnesol 2,4,5−Trichlorophenol 2−Chloroacetophenone 4−Chloro−1,2−diaminobenzene Naled Aplaviroc hydrochloride Phosalone Fluoxastrobin Methyl red Triphenyl phosphate Oxadiazon Ro 23−7637 Coumaphos Troglitazone PharmaGSID_47330 Cyazofamid Aldrin Chloroallyl methenamine chlori CP−401387 Quinoxyfen UK−416244 FR167356 CP−728663 CP−085958 Z−Tetrachlorvinphos Azamethiphos 2−Methyl−4,6−dinitrophenol Trelanserin Codlelure C.I. Disperse Orange 37 PharmaGSID_48172 N−Phenyl−1−naphthylamine Ethalfluralin Amitraz Hexythiazox Digoxin Triclocarban CJ−013790 Bisphenol A diglycidyl ether CP−105696 Epoxiconazole Formamide Profenofos 2,2',6,6'−Tetrachlorobisphenol Endosulfan I Triglycidyl isocyanurate 2−Aminoanthraquinone Ingliforib PFOSA Bifenthrin N−(Cyclohexylthio)phthalimide Tricresyl phosphate Simvastatin tert−Butylhydroquinone 2−Hydroxybenzonitrile 1−Tetradecanol SSR161421 1−Dodecyl−2−pyrrolidinone Maneb Di(propylene glycol) dibenzoat Linoleic acid Tri−allate Dodecylbenzenesulfonic acid Linolenic acid 1,4−Diaminoanthraquinone SSR150106 Sodium myristyl sulfate C.I. Acid Red 114 Sodium (2−pyridylthio)−N−oxide Picoxystrobin PharmaGSID_47333 Fludioxonil Fenamidone CJ−013610 1,10−Phenanthroline Famoxadone SB243213A SSR69071 Enterolactone Ranitidine 2−Nitrotoluene Ethion Trifloxystrobin PFOS FD&C Red 3 1−Tridecanol 4−Methylstyrene Dimethyl methylphosphonate 1−Dodecanamine m−Xylene PharmaGSID_47263 Indoxacarb 4−Hexylaniline Oleyl sarcosine 4−tert−Butyltoluene 2,6,10−Trimethyl−2,6,10−triaza Silica (−)−alpha−Pinene Sodium ethasulfate 1−(6−tert−Butyl−1,1−dimethyl−2 Sodium tridecyl sulfate Sodium dodecyl sulfate C.I. Acid Orange 8, monosodium Oxytetracycline dihydrate Sodium lauryl polyoxyethylene C.I. Acid Orange 7 Sodium 4−octylbenzenesulfonate Sulfasalazine Bromoxynil Dodecylbenzene sulfonate triet Sodium dodecylbenzenesulfonate Decanal Hexyl benzoate 2,3−Dihydro−2,2−dimethyl−7−ben Arabinose 2,4−Diisopropylphenol (+/−)−alpha−Methylbenzyl aceta (−)−beta−Pinene (2−Dodecenyl)succinic anhydrid (2E)−2−Hexenal (2E)−3−Phenylprop−2−enal (2Z)−3,7−Dimethylocta−2,6−dien (3,5−Dimethyl−1H−pyrazol−1−yl) (3Z)−3−Hexenyl acetate (4Z)−4−Decenal (9Z,12R)−12−Hydroxyoctadec−9−e (Dicyclopentadienyloxy)ethyl m (E)−1,2−Dichloroethylene (E)−Anethole (Methylcyclopentadienyl)tricar (S)−(−)−beta−Citronellol (Z)−11−Hexadecenal (Z)−3−Hexen−1−ol 1,1,1,3,5,5,5−Heptamethyltrisi 1,1,2,2−Tetrahydroperfluoro−1− 1,1−Bis(3,4−dimethylphenyl)eth 1,1−Dimethyl−2−phenylethyl but 1,1−Dimethylhydrazine 1,2,3,6−Tetrahydrophthalimide 1,2,3−Benzotriazole 1,2,3−Trichlorobenzene 1,2,3−Trichloropropane 1,2,4,5−Tetrachlorobenzene 1,2,4,5−Tetramethylbenzene 1,2,4−Trichlorobenzene 1,2,4−Trimethylbenzene 1,2−Benzenedicarboxylic acid, 1,2−Dibromoethane 1,2−Dichloro−4−(trifluoromethy 1,2−Dichlorobenzene 1,2−Dimethyl−3−nitrobenzene 1,2−Dimethyl−4−nitrobenzene 1,2−Diphenoxyethane 1,2−Diphenylethanone 1,2−Diphenylhydrazine 1,2−Ethanediamine dihydriodide 1,2−Ethanediol diacetate 1,2−Phenylenediamine 1,2−Propylene glycol 1,3,5,7−Tetramethyl−1,3,5,7−te 1,3,5−Triethylhexahydro−s−tria 1,3,5−Triisopropylbenzene 1,3,5−Trimethylbenzene 1,3−Benzenediamine 1,3−Benzenedicarbonyl dichlori 1,3−Benzenedicarboxylic acid 1,3−Benzenedimethanamine 1,3−Butanediol 1,3−Butyleneglycol dimethacryl 1,3−Cyclopentadiene 1,3−Dibromo−5,5−dimethylhydant 1,3−Dichloro−2−propanol 1,3−Dichloro−5,5−dimethylhydan 1,3−Dichlorobenzene 1,3−Diisopropylbenzene 1,3−Dimethyl−4−nitrobenzene 1,3−Dinitrobenzene 1,3−Diphenyl−1,3−propanedione 1,3−Divinyl−1,1,3,3−tetramethy 1,3−Propane sultone 1,4−Benzenediamine 1,4−Bis(N−isopropylamino)anthr 1,4−Butanediol 1,4−Cyclohexanedicarboxylic ac 1,4−Dichlorobenzene 1,4−Dimethylnaphthalene 1,4−Heptanolide 1,5,9−Cyclododecatriene 1,5−Naphthalenediamine 1,6−Diisocyanatohexane 1,6−Hexanediamine 1,8−Cineol 1−(2−Aminoethyl)piperazine 1−(Bromomethyl)−3−phenoxybenze 1−(Hydroxymethyl)−5,5−dimethyl 1−Amino−2−propanol 1−Benzylquinolinium chloride 1−Bromo−4−fluorobenzene 1−Cedr−8−en−9−ylethanone 1−Chloro−4−(trifluoromethyl)be 1−Chloro−4−nitrobenzene 1−Decanol