Insect Bites and Stings
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
RESEARCH ARTICLE Anti-Glioma Effect of Pseudosynanceia
DOI:10.31557/APJCP.2021.22.7.2295 Effect of Pseudosynanceia Melanostigma Venom on Glioblastoma Cells RESEARCH ARTICLE Editorial Process: Submission:02/14/2021 Acceptance:07/15/2021 Anti-Glioma Effect of Pseudosynanceia Melanostigma Venom on Isolated Mitochondria from Glioblastoma Cells Maral Ramezani, Fatemeh Samiei, Jalal Pourahmad* Abstract Background: Glioblastoma is the most common primary malignant tumor of the central nervous system that occurs in the spinal cord or brain. Pseudosynanceia Melanostigma is a venomous stonefish in the Persian Gulf, which our knowledge about is little. This study’s goal is to investigate the toxicity of stonefish crude venom on mitochondria isolated from U87 cells. Methods: In the first stage, we extracted venom stonefish and then isolated mitochondria have exposed to different concentrations of venom. Finally, mitochondrial toxicity parameters (Succinate dehydrogenase (SDH) activity, Reactive oxygen species (ROS), cytochrome c release, Mitochondrial Membrane Potential (MMP), and mitochondrial swelling) have evaluated. Results: To determine mitochondrial parameters, we used 115, 230, and 460 µg/ml concentrations. The results of our study show that the venom of stonefish selectively increases upstream parameters of apoptosis such as mitochondrial swelling, cytochrome c release, MMP collapse and ROS. Conclusion: This study suggests that Pseudosynanceia Melanostigma crude venom has selectively caused toxicity by increasing active mitochondrial oxygen radicals. This venom could potentially be a candidate for the treatment of glioblastoma. Keywords: Mitochondria- glioblastoma- fish venoms- cell line- tumor- toxicity-Persian Gulf Asian Pac J Cancer Prev, 22 (7), 2295-2302 Introduction freshwater or saltwater. Marine animals most commonly used for animals live in saltwater, i.e. in oceans, seas, Glioblastoma multiform is the most common group of etc. -
Skin Care, Insect Bites and Stings
DEPARTMENT KLINISCHE WETENSCHAPPEN | MEDISCHE DIENSTEN Kronenburgstraat 43/3, 2000 Antwerpen | Fax: +32 3 247 64 10 Updated version (20/05/2015 – AVG) see: www.travelhealth.be SKIN CARE, INSECT BITES AND STINGS Sun The closer you get to the Equator, the more intense sunlight becomes. Sunbathing in the tropics has to be done in moderation. Protective clothing and hats are recommended. Apply sun cream with high sun protection factor (30 or more) to exposed skin regularly (every two hours) and carefully. Apply sun cream after bathing and avoid long water exposure since sun stroke will be imminent in spite of reduced heat feeling. Avoid perfumed sun creams and check whether or not used creams or medication can cause "sun allergy" (photo-toxic or photo-allergic reactions). We would like to refer to point 5 of the European cancer code: avoid excessive exposure to sun and sunburn during childhood (increased risk of melanomas in later life). Do not take a course of sunbed sessions before going on holiday as the sun tan obtained through UV-A does not give any extra protection against the natural UV-rays. When using sun creams and insect repellents based on DEET, recent studies have shown that DEET reduces the effectiveness of the sun cream, but that sun creams do not have a negative influence on the effectiveness of DEET. It is advisable, therefore, to apply the insect repellent (DEET or another repellent) with the sun lotion and then to take additional precautions to protect against UV (e.g. a sun cream with a higher protection factor). -
Allergic Reactions to Bites and Stings
Allergic Reactions to Bites and Stings ASCIA EDUCATION RESOURCES (AER) PATIENT INFORMATION Most insect bites and stings result in a localised itch and swelling that settles within a few days. Severe allergic reactions (anaphylaxis) to insects are relatively uncommon, and are usually due to bees, wasps or the Australian Jack Jumper ant. Fortunately, effective treatments are available to treat allergic reactions to bites and stings. Stinging insects are a common cause of anaphylaxis Allergies to venoms from stinging insects are one of the most common causes of severe allergic reactions (anaphylaxis) in Australia. Symptoms include an all over rash, swelling of tongue or throat, trouble breathing, gut cramps, diarrhoea, vomiting or even a drop in blood pressure (shock). Although the insects are all hymenoptera (which means membranous winged insects), their venoms are very different. Allergy to one type of stinging insect does not usually increase the risk of reaction to another. The Honey Bee is the most common cause of allergic reactions in Australia. Paper Wasps and European Wasps can sting multiple times. The European Wasp is becoming an increasing problem in Australia, is particularly aggressive and likes to get inside drink cans at barbeques, although the more familiar Paper Wasp is responsible for the majority of serious stings. The Australian Jack Jumper Ant (Myrmecia pilosula) is a medium sized black bull ant prevalent down the eastern side of Australia and Tasmania. It can be recognised by its characteristic hopping motion when it walks. It is a very aggressive ant and its sting can cause severe local pain. Severe allergic reactions are much more common than is seen with more common bull ants. -
Spider Bites
Infectious Disease Epidemiology Section Office of Public Health, Louisiana Dept of Health & Hospitals 800-256-2748 (24 hr number) www.infectiousdisease.dhh.louisiana.gov SPIDER BITES Revised 6/13/2007 Epidemiology There are over 3,000 species of spiders native to the United States. Due to fragility or inadequate length of fangs, only a limited number of species are capable of inflicting noticeable wounds on human beings, although several small species of spiders are able to bite humans, but with little or no demonstrable effect. The final determination of etiology of 80% of suspected spider bites in the U.S. is, in fact, an alternate diagnosis. Therefore the perceived risk of spider bites far exceeds actual risk. Tick bites, chemical burns, lesions from poison ivy or oak, cutaneous anthrax, diabetic ulcer, erythema migrans from Lyme disease, erythema from Rocky Mountain Spotted Fever, sporotrichosis, Staphylococcus infections, Stephens Johnson syndrome, syphilitic chancre, thromboembolic effects of Leishmaniasis, toxic epidermal necrolyis, shingles, early chicken pox lesions, bites from other arthropods and idiopathic dermal necrosis have all been misdiagnosed as spider bites. Almost all bites from spiders are inflicted by the spider in self defense, when a human inadvertently upsets or invades the spider’s space. Of spiders in the United States capable of biting, only a few are considered dangerous to human beings. Bites from the following species of spiders can result in serious sequelae: Louisiana Office of Public Health – Infectious Disease Epidemiology Section Page 1 of 14 The Brown Recluse: Loxosceles reclusa Photo Courtesy of the Texas Department of State Health Services The most common species associated with medically important spider bites: • Physical characteristics o Length: Approximately 1 inch o Appearance: A violin shaped mark can be visualized on the dorsum (top). -
Avoiding and Treating Work-Related Insect Bites and Stings
FACT SHEET Avoiding and Treating Work-Related Insect Bites and Stings This WorkCare Fact Sheet describes work-related bite and sting risks, symptoms, treatment and preventive measures. Bites and stings are a relatively common occurrence for people who work outdoors and in enclosed environments where bees and wasps, fire ants, insects and arachnids (spiders, scorpions, ticks and mites) feel at home. Employers and workers are encouraged to understand exposure risks, how to recognize and respond to stings and bites, and what they can do to prevent them. Under 29 CFR Part 1904 – Recording and Reporting Occupational Injuries and Illnesses, the Occupational Safety and Health Administration (OSHA) considers bites and stings to be recordable when an employee who is bitten or stung while working receives medical treatment beyond first aid. First aid is defined in1904.7 (b)(5)(ii). Exposure Risk Thousands of people in the U.S. are stung or bitten each year. Exposed arms and hands tend to be more susceptible to stings and bites among workers than legs and feet, which are usually protected by clothing and enclosed shoes. In a study of occupationally related bites and stings, the head, one of the most exposed body parts, accounted for one-tenth of cases involving insects and arachnids; a third of those cases affected the eyes. An estimated 90 to 100 people die each year in the U.S. as a result of allergic reactions to bites and stings. Overall, bite- and sting-related injuries and fatalities may be misdiagnosed as heart attack or sunstroke, or attributed to other causes, according to the National Institute for Occupational Safety and Health (NIOSH). -
Unit 3 Bites and Stings
First Aid in Common and Environmental Emergencies UNIT 3 BITES AND STINGS Structure 3.0 Introduction 3.1 Objectives 3.2 Bites and Stings 3.2.1 Definition, Causes, Types and Recognition of Bites and Stings 3.2.2 Assessment of the Victim and General First Aid 3.3 Various Bites/Stings 3.3.1 Scorpion Bite and Spider Bite 3.3.2 Snake Bite 3.3.3 Insect Bite 3.3.4 Animal Bites (Dog Bite/Monkey Bites) 3.3.5 Human Bites 3.4 Let Us Sum Up 3.5 Keywords 3.6 Answers to Check Your Progress 3.7 References and Further Readings 3.0 INTRODUCTION Bites and stings are commonly seen in the rural and remote areas. Nowadays, however, they can occur in urban areas also. Lakhs of people every year are bitten or stung by someone or something. These emergencies include bites and stings due to various reasons. These bites or stings need to be identified and treated early as they affect some part or the whole of the body which can cause mild, moderate or severe reaction and can even be life-threatening. Most are not medical emergencies but however, treatment is usually required if there is bleeding, wounds or infection. All bites and stings are not same. Different First Aid treatment and care is needed depending on the type of insect or animal that has caused the bite. Some species are more dangerous and cause more harm compared to others. Hence, in this unit we shall discuss the different types of bites and stings, causes, recognition and first aid in these situations. -
ALLERGIC REACTIONS/ANAPHYLAXIS Connie J
Northwest Community EMS System Paramedic Education Program ALLERGIC REACTIONS/ANAPHYLAXIS Connie J. Mattera, M.S., R.N., EMT-P Reading assignments Text-Vol.1 pp. 235, 1272-1276 SOP: Allergic Reactions/ Anaphylactic Shock Assumed knowledge: Drugs: Epinephrine 1:1,000, 1:10,000; albuterol, ipratropium, dopamine, glucagon KNOWLEDGE OBJECTIVES Upon reading the assigned text assignments and completion of the class and homework questions, each participant will independently do the following with at least an 80% degree of accuracy and no critical errors: 1. Define allergic reaction. 2. Describe the incidence, morbidity and mortality of allergic reactions and anaphylaxis. 3. Identify risk factors that predispose a patient to anaphylaxis. 4. Explain the physiology of the immune system following exposure to an allergen including activation of histamine receptors and the formation of antibodies. 5. Discuss the pathophysiology of allergic reactions and anaphylaxis. 6. Describe the common modes by which allergens enter the body. 7. Compare and contrast natural and acquired and active vs. passive immunity. 8. Identify antigens most frequently associated with anaphylaxis. 9. Differentiate the clinical presentation and severity of risk for a mild, moderate and severe allergic reaction with an emphasis on recognizing an anaphylactic reaction. 10. Integrate the pathophysiologic principles of anaphylaxis with treatment priorities. 11. Sequence care per SOP for patients with mild, moderate and severe allergic reactions. CJM: S14 NWC EMSS Paramedic Education Program ALLERGIC REACTIONS/ANAPHYLAXIS Connie J. Mattera, M.S., R.N., EMT-P I. Immune system A. Principal body system involved in allergic reactions. Others include the cutaneous, cardiovascular, respiratory, nervous, and gastrointestinal systems. -
Violent Incidents Between Humans and Orcas in Captivity
Violent incidents between humans and orcas in captivity Several accounts of violent incidents with humans have appeared in books and news clips, with little information on the dates or details of those incidents. Other descriptions have made headlines, and some were captured on video tape. There are also anecdotal reports of incidents that were never officially documented. NO. DATE AQUARIUM WHALEs INCIDENT SOURCE early years New York When water level was lowered for pool cleaning, young female Lupa sent Edward R. Riciuti, , New #1 1968 Lupa York, Walker & Co., 1973, Aquarium, USA trainers scrambling from the pool, snapping her jaws threatening. pp. 227-228. Edward R. Riciuti, Killers of the Sea, New York, Young male Cuddles became so increasingly aggressive, having a hold of at Walker & Co., 1973, pp. Flamingo Park, least two trainers, that keepers had to clean the pool from the protection of a 227-228; Reading #2 1969-1970 Cuddles England shark cage. Cuddles also dragged keeper Don Robinson into the pool when he Eagle, August 15, was at Dudley Zoo but that was possibly a PR stunt. 1971; Doug Cartlidge, personal communication, March 2010. Karen Pryor writes, "I have since heard... of at least one killer whale which Karen Pryor, Lads Before the Wind, New York, #3 1970s unknown unknown launched an unprovoked attack on a favorite trainer, in normal circumstances, Harper & Row, 1976, p. savaged him very badly, and nearly killed him." 220. Vancouver Trainer Doug Pemberton described young female Skana as the dominant Cranky killer whales put trainers through their #4 1970's Aquarium, Skana animal in the pool. -
Arthropod Envenomations: Immunologic and Toxicologic Considerations Cyrus Rangan, MD, FAAP, ACMT
Emergency Department Evaluation and Treatment for Children With Arthropod Envenomations: Immunologic and Toxicologic Considerations Cyrus Rangan, MD, FAAP, ACMT Arthropod envenomations are a significant cause of environmental injury in children. Bees, wasps, and spiders inflict injury via specialized venoms with a broad range of components, mechanisms, and potential treatments. Immunologic and toxicologic considerations in the evaluation and management of arthropod envenomations are important for the under- standing of the progression of envenomations, prompt diagnosis of severe conditions including anaphylaxis, and the use of antivenom in selected cases. Clin Ped Emerg Med 8:104-109 ª 2007 Published by Elsevier Inc. KEYWORDS envenomation, arthropod, arachnida, hymenoptera rthropod bites and stings accounted for more than ever, clinical symptoms of envenomation and treatment A75000 reports to poison control centers in the are similar. Bees are attracted to carbon dioxide (hence, United States in 2005 [1]. The phylum Arthropoda the predilection for bees to fly around the facial area), includes 2 clinically important classes: Insecta (order: bright colors (ie, clothing), and sweet odors (ie, Hymenoptera—bees, wasps, yellow jackets, and ants), perfumes, fragrances). Children commonly believe that and Arachnida (ticks, scorpions, and spiders). Virtually bees are aggressive insects, but they are mostly docile all arthropods possess some form of venom for immobi- creatures; indeed, the sometimes fearful behavior of lization and digestion of prey, yet only a select few species children around a nearby bee may increase the risk of a have developed venom delivery mechanisms capable of sting. Mass envenomations may occur when a hive is poisoning humans [2]. Pathophysiologic mechanisms of physically disturbed by children throwing rocks or other venom vary considerably among arthropods, and clinical objects at the hive [3]. -
Awareness, Prevention and Treatment of World-Wide Marine Stings and Bites
Awareness, Prevention and Treatment of world-wide marine stings and bites Dr Peter Fenner Honorary Medical Officer, Surf Life Saving Australia International Life Saving Federation Medical/Rescue Conference Proceedings September 1997 Abstract The most common world-wide first aid treatment used by the average lifesaver/lifeguard is the treatment of marine envenomation, especially the treatment of jellyfish stings. It is important to use the correct first aid treatment for each type of envenomation. This study provides a simplified protocol for: - 1. Awareness of the geographical distribution and possibilities of envenomation enabling: - 2. Preventative strategies to reduce morbidity and mortality from marine envenomation 3. First aid treatment of marine envenomation by jellyfish or other marine animals This discussion is based on protocols developed for Surf Life Saving Australia and other first aid providers in Australia over the past ten years. Their success has been proven by a 30% reduction in the number of stings over the past 10 years (statistics from the author’s records). Information for this article has been taken from: - 1. Venomous and poisonous marine animals: a medical and biological handbook produced by Surf Life Saving Queensland 2. The global problem of cnidarian stinging. MD Thesis by the author for the University of London. Introduction The global problem of marine envenomation is not fully appreciated. Each year hundreds of deaths occur from poisoning (by ingestion or eating) or by envenomation (stinging by jellyfish, or biting by venomous marine animals). The morbidity is even greater with jellyfish stings world-wide being numbered in their millions. Each summer it is estimated that up to half a million stings occur on the east coast of the United States from the Portuguese man-o’-war (Physalia physalis). -
Instruction Sheet: Bee Sting, Local Reaction
University of North Carolina Wilmington Abrons Student Health Center INSTRUCTION SHEET: BEE STING, LOCAL REACTION The Student Health Provider has diagnosed a mild allergic reaction to a bee/wasp sting. Fortunately, most bee stings are not serious and cause only temporary swelling, redness, and pain at the sting site. Rarely, a whole-body allergic reaction occurs; shock can result. The stinger, if still in the wound, should be removed; if the stinger is left in place, bee toxin continues to enter the body, increasing the reaction. A stinger should be removed with a piece of paper or credit card, using a sideways scraping motion. A pair of tweezers can also be used to remove the stinger, but try not to squeeze the stinger, or more toxin can be pushed inside the wound. Realize that swelling may increase at first, even with treatment. Measures can be taken, however, to minimize the reaction to bee stings. MEASURES YOU SHOULD TAKE TO HELP TREAT YOUR BEE STING: 1. Rest and elevate the affected body part. Rest and elevation help reduce swelling and pain. 2. Apply cold packs to the area off-and-on for the first 24 hours after injury. Cold helps ease discomfort, and minimizes additional swelling. Do not apply ice directly to the area, causing discomfort. Rather, aim for coolness, yet comfort, applying a layer or two of cloth between the cold pack and affected area. 3. Take over-the-counter antihistamines: In the morning, take a non-sedating antihistamine such as loratadine, 10 mg daily. At night, take diphenhydramine (Benadryl), 25 mg, 1 or 2 every 6 hours for itching and swelling. -
A Guide to Harmful and Toxic Creatures in the Goa of Jordan
Published by the Royal Marine Conservation Society of Jordan. P. O. Box 831051, Abdel Aziz El Thaalbi St., Shmesani 11183. Amman Copyright: © The Royal Marine Conservation Society of Jordan Reproduction of this publication for educational and other non- commercial purposes is authorized without prior written approval from the copyright holder provided the source is fully acknowledged. ISBN: 978-9957-8740-1-8 Deposit Number at the National Library: 2619/6/2016 Citation: Eid, E and Al Tawaha, M. (2016). A Guide to Harmful and Toxic Creature in the Gulf of Aqaba of Jordan. The Royal Marine Conservation Society of Jordan. ISBN: 978-9957-8740-1-8. Pp 84. Material was reviewed by Dr Nidal Al Oran, International Research Center for Water, Environment and Energy\ Al Balqa’ Applied University,and Dr. Omar Attum from Indiana University Southeast at the United State of America. Cover page: Vlad61; Shutterstock Library All photographs used in this publication remain the property of the original copyright holder, and it should not be reproduced or used in other contexts without permission. 1 Content Index of Creatures Described in this Guide ......................................................... 5 Preface ................................................................................................................ 6 Part One: Introduction ......................................................................................... 8 1.1 The Gulf of Aqaba; Jordan ......................................................................... 8 1.2 Aqaba;