Violent Incidents Between Humans and Orcas in Captivity
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RESEARCH ARTICLE Anti-Glioma Effect of Pseudosynanceia
DOI:10.31557/APJCP.2021.22.7.2295 Effect of Pseudosynanceia Melanostigma Venom on Glioblastoma Cells RESEARCH ARTICLE Editorial Process: Submission:02/14/2021 Acceptance:07/15/2021 Anti-Glioma Effect of Pseudosynanceia Melanostigma Venom on Isolated Mitochondria from Glioblastoma Cells Maral Ramezani, Fatemeh Samiei, Jalal Pourahmad* Abstract Background: Glioblastoma is the most common primary malignant tumor of the central nervous system that occurs in the spinal cord or brain. Pseudosynanceia Melanostigma is a venomous stonefish in the Persian Gulf, which our knowledge about is little. This study’s goal is to investigate the toxicity of stonefish crude venom on mitochondria isolated from U87 cells. Methods: In the first stage, we extracted venom stonefish and then isolated mitochondria have exposed to different concentrations of venom. Finally, mitochondrial toxicity parameters (Succinate dehydrogenase (SDH) activity, Reactive oxygen species (ROS), cytochrome c release, Mitochondrial Membrane Potential (MMP), and mitochondrial swelling) have evaluated. Results: To determine mitochondrial parameters, we used 115, 230, and 460 µg/ml concentrations. The results of our study show that the venom of stonefish selectively increases upstream parameters of apoptosis such as mitochondrial swelling, cytochrome c release, MMP collapse and ROS. Conclusion: This study suggests that Pseudosynanceia Melanostigma crude venom has selectively caused toxicity by increasing active mitochondrial oxygen radicals. This venom could potentially be a candidate for the treatment of glioblastoma. Keywords: Mitochondria- glioblastoma- fish venoms- cell line- tumor- toxicity-Persian Gulf Asian Pac J Cancer Prev, 22 (7), 2295-2302 Introduction freshwater or saltwater. Marine animals most commonly used for animals live in saltwater, i.e. in oceans, seas, Glioblastoma multiform is the most common group of etc. -
Seaworld Orlando in Florida
SeaWorld Orlando in Florida SeaWorld is a very popular theme park and marine-life zoo in Orlando, Florida. The park hosts many educational programs, shows, exhibitions and other fun experiences, making it immensely popular with families, teachers and students. This 200-acres marine life theme park, is filled with aquatic fun and thrilling adventures. This park is currently being operated and managed by the Sea World Parks and Entertainment, a subsidiary of the Blackstone Group. The smashing success of the first SeaWorld Park prompted the founders to open another park at a different location; the SeaWorld Park at Ohio was opened in 1968, and was soon followed by the establishment of the SeaWorld, Orlando in the year 1973. Orlando was selected as an ideal location due to its pleasant climate almost all through the year. Also, with the opening of the Walt Disney parks, a large number of visitors were already visiting the city. SeaWorld in Orlando, unlike other theme parks has a refreshing landscape, with no broken up themed islands in the park. The main landscaping feature of the park is its pathways with animal enclosures on either side. The main entrance to the park is decorated with lush tropical landscaping, which has a Florida-based theme, a huge artificial freshwater marina, and an iconic lighthouse based on a Shamu theme. The neighboring park, Discovery Cove, along with the SeaWorld, forms a greater entertainment area, which is an ideal destination for vacationers. SeaWorld, Orlando, offers many shows, exhibitions, rides, and park experiences. Live shows, animal exhibits, and the 3D computer animated films at the Theater Dome promise the visitors a great time. -
Animal Behavior & Training
NATIONAL SCIENCE EDUCATION STANDARDS Pre/Post Assessment SeaWorld and Busch Gardens education programs and Use this assessment to discover how publications support the National Science Education Standards. The Animal Behavior and Training much your students already know Teacher’s Guide for grades K–3 includes connections about animal behavior and training to the following standards: before you begin this unit, and later as a conclusion to your study. Life Sciences Characteristics of organisms Name some animals that can be Life cycles of organisms trained to perform in marine life Organisms and environments shows. Describe the kinds of things they do in a show. Personal and Social Perspectives Types of resources What does behavior mean? Give Changes in environments some examples of human behavior. Science and technology in local challenges Choose an ocean animal and role- History and Nature of Science play its behavior for avoiding Science as a human endeavor predators. Role-play its behavior for finding food. Science as Inquiry Describe how you might be able to Abilities necessary to do scientific inquiry Understanding about scientific inquiry communicate with someone who doesn’t speak your language. Unifying Concepts and Processes Show how you might get a friend to Systems, order, and organization touch a particular object using only Evidence, models, and explanation the words “hot” and “cold.” Change, constancy, and measurement Evolution and equilibrium Draw or paint a picture that shows Form and function what an animal trainer might do in National Research Council. National Science Education a typical work day. Standards. Washington, D.C.: National Academy Press, 1996. -
Captive Orcas
Captive Orcas ‘Dying to Entertain You’ The Full Story A report for Whale and Dolphin Conservation Society (WDCS) Chippenham, UK Produced by Vanessa Williams Contents Introduction Section 1 The showbiz orca Section 2 Life in the wild FINgerprinting techniques. Community living. Social behaviour. Intelligence. Communication. Orca studies in other parts of the world. Fact file. Latest news on northern/southern residents. Section 3 The world orca trade Capture sites and methods. Legislation. Holding areas [USA/Canada /Iceland/Japan]. Effects of capture upon remaining animals. Potential future capture sites. Transport from the wild. Transport from tank to tank. “Orca laundering”. Breeding loan. Special deals. Section 4 Life in the tank Standards and regulations for captive display [USA/Canada/UK/Japan]. Conditions in captivity: Pool size. Pool design and water quality. Feeding. Acoustics and ambient noise. Social composition and companionship. Solitary confinement. Health of captive orcas: Survival rates and longevity. Causes of death. Stress. Aggressive behaviour towards other orcas. Aggression towards trainers. Section 5 Marine park myths Education. Conservation. Captive breeding. Research. Section 6 The display industry makes a killing Marketing the image. Lobbying. Dubious bedfellows. Drive fisheries. Over-capturing. Section 7 The times they are a-changing The future of marine parks. Changing climate of public opinion. Ethics. Alternatives to display. Whale watching. Cetacean-free facilities. Future of current captives. Release programmes. Section 8 Conclusions and recommendations Appendix: Location of current captives, and details of wild-caught orcas References The information contained in this report is believed to be correct at the time of last publication: 30th April 2001. Some information is inevitably date-sensitive: please notify the author with any comments or updated information. -
Spider Bites
Infectious Disease Epidemiology Section Office of Public Health, Louisiana Dept of Health & Hospitals 800-256-2748 (24 hr number) www.infectiousdisease.dhh.louisiana.gov SPIDER BITES Revised 6/13/2007 Epidemiology There are over 3,000 species of spiders native to the United States. Due to fragility or inadequate length of fangs, only a limited number of species are capable of inflicting noticeable wounds on human beings, although several small species of spiders are able to bite humans, but with little or no demonstrable effect. The final determination of etiology of 80% of suspected spider bites in the U.S. is, in fact, an alternate diagnosis. Therefore the perceived risk of spider bites far exceeds actual risk. Tick bites, chemical burns, lesions from poison ivy or oak, cutaneous anthrax, diabetic ulcer, erythema migrans from Lyme disease, erythema from Rocky Mountain Spotted Fever, sporotrichosis, Staphylococcus infections, Stephens Johnson syndrome, syphilitic chancre, thromboembolic effects of Leishmaniasis, toxic epidermal necrolyis, shingles, early chicken pox lesions, bites from other arthropods and idiopathic dermal necrosis have all been misdiagnosed as spider bites. Almost all bites from spiders are inflicted by the spider in self defense, when a human inadvertently upsets or invades the spider’s space. Of spiders in the United States capable of biting, only a few are considered dangerous to human beings. Bites from the following species of spiders can result in serious sequelae: Louisiana Office of Public Health – Infectious Disease Epidemiology Section Page 1 of 14 The Brown Recluse: Loxosceles reclusa Photo Courtesy of the Texas Department of State Health Services The most common species associated with medically important spider bites: • Physical characteristics o Length: Approximately 1 inch o Appearance: A violin shaped mark can be visualized on the dorsum (top). -
ORLANDO Vacation Guide & Planning Kit
ORLANDO Vacation Guide & Planning Kit Orlando, Florida Overview Table of Contents Orlando, the undisputed “Vacation Capital of the World,” boasts Orlando, Florida Overview 1 beautiful weather year round, world-class theme parks, thrilling water Getting To And Around Orlando 2 parks, unique attractions, lively dinner theaters, outdoor recreation, Orlando Theme Parks 3 luxurious health spas, fine dining, trendy nightclubs, great shopping Walt Disney World Resort 3 opportunities, championship golf courses and much more. The seat of Universal Orlando® Resort 4 Orange County, Florida, Orlando boasts a population of approximately SeaWorld® Orlando 4 228,000 – making it the sixth largest city in Florida. Easily accessible Orlando Attractions 5 via Interstate 4 and the Florida Turnpike, Orlando is also home to the Orlando Dining 8 Orlando International Airport – the 10th busiest airport in the United Orlando Live Entertainment 8 States and the 20th busiest in the world. Orlando Shopping 9 Orlando Golf 10 Experience the magic of Walt Disney World® Resort – Discover the Orlando Annual Events 11 enchanted lands of Disney’s Magic Kingdom® Park, blast off into the Orlando Travel Tips 13 future at Epcot®, journey through the fascinating history of Hollywood movies at Disney’s Hollywood Studios™ and take a fun-filled safari expedition at Disney’s Animal Kingdom® Theme Park. Don’t miss the thrilling rides at the two amazing theme parks of Universal Orlando® Resort – Universal Studios® Florida and Universal’s Islands of Adventure®, as well as the up-close animal encounters of SeaWorld® Orlando. Cool off at one of Orlando’s state-of-the-art water parks such as Aquatica, Wet ‘n Wild® Water Park, Disney’s Blizzard Beach or Disney’s Typhoon Lagoon. -
THE CASE AGAINST Marine Mammals in Captivity Authors: Naomi A
s l a m m a y t T i M S N v I i A e G t A n i p E S r a A C a C E H n T M i THE CASE AGAINST Marine Mammals in Captivity The Humane Society of the United State s/ World Society for the Protection of Animals 2009 1 1 1 2 0 A M , n o t s o g B r o . 1 a 0 s 2 u - e a t i p s u S w , t e e r t S h t u o S 9 8 THE CASE AGAINST Marine Mammals in Captivity Authors: Naomi A. Rose, E.C.M. Parsons, and Richard Farinato, 4th edition Editors: Naomi A. Rose and Debra Firmani, 4th edition ©2009 The Humane Society of the United States and the World Society for the Protection of Animals. All rights reserved. ©2008 The HSUS. All rights reserved. Printed on recycled paper, acid free and elemental chlorine free, with soy-based ink. Cover: ©iStockphoto.com/Ying Ying Wong Overview n the debate over marine mammals in captivity, the of the natural environment. The truth is that marine mammals have evolved physically and behaviorally to survive these rigors. public display industry maintains that marine mammal For example, nearly every kind of marine mammal, from sea lion Iexhibits serve a valuable conservation function, people to dolphin, travels large distances daily in a search for food. In learn important information from seeing live animals, and captivity, natural feeding and foraging patterns are completely lost. -
Seaworld San Diego 2020 Fact Sheet
Media: For more information, contact SeaWorld Public Relations at (619) 225-3241 or [email protected] SEAWORLD SAN DIEGO 2020 FACT SHEET OVERVIEW: SeaWorld San Diego is one of the most popular marine parks in the world and a global leader in marine animal care and welfare, education, conservation, research and rescue. Through exciting and educational attractions, presentations, shows and exhibits, SeaWorld creates fun and meaningful experiences where guests can explore, become inspired to care about animals and wild wonders of the world, and to act to help protect them. SeaWorld San Diego, which opened in March of 1964, is one of 12 parks operated by SeaWorld Parks & Entertainment. Every visit to a SeaWorld park helps support its animal rescue program. Seeing animals at SeaWorld supports saving them in the wild. DESCRIPTION: Spread across 190 acres on beautiful Mission Bay Park, SeaWorld San Diego is known for spectacular animal shows, interactive attractions, aquariums, rides, lush landscaping and education programs for all ages. Just in time for summer, the park will debut Emperor, California’s tallest, fastest and longest dive coaster. LOCATION: Off I-5 on SeaWorld Drive on Mission Bay, 10 minutes north of downtown San Diego, the San Diego International Airport and Amtrak’s downtown station. PARK HOURS: Opening and closing times vary by season. Hours are extended during seasonal periods, such as summer and winter holidays. Call (619) 222-4SEA or visit www.SeaWorldSanDiego.com. ADMISSION: $93.99, ages 10 and older; $88.99, ages 3–9; free, under 3. Annual Pass Memberships, the 2020 Fun Card and other ticket and Pass products make SeaWorld an even better value. -
Awareness, Prevention and Treatment of World-Wide Marine Stings and Bites
Awareness, Prevention and Treatment of world-wide marine stings and bites Dr Peter Fenner Honorary Medical Officer, Surf Life Saving Australia International Life Saving Federation Medical/Rescue Conference Proceedings September 1997 Abstract The most common world-wide first aid treatment used by the average lifesaver/lifeguard is the treatment of marine envenomation, especially the treatment of jellyfish stings. It is important to use the correct first aid treatment for each type of envenomation. This study provides a simplified protocol for: - 1. Awareness of the geographical distribution and possibilities of envenomation enabling: - 2. Preventative strategies to reduce morbidity and mortality from marine envenomation 3. First aid treatment of marine envenomation by jellyfish or other marine animals This discussion is based on protocols developed for Surf Life Saving Australia and other first aid providers in Australia over the past ten years. Their success has been proven by a 30% reduction in the number of stings over the past 10 years (statistics from the author’s records). Information for this article has been taken from: - 1. Venomous and poisonous marine animals: a medical and biological handbook produced by Surf Life Saving Queensland 2. The global problem of cnidarian stinging. MD Thesis by the author for the University of London. Introduction The global problem of marine envenomation is not fully appreciated. Each year hundreds of deaths occur from poisoning (by ingestion or eating) or by envenomation (stinging by jellyfish, or biting by venomous marine animals). The morbidity is even greater with jellyfish stings world-wide being numbered in their millions. Each summer it is estimated that up to half a million stings occur on the east coast of the United States from the Portuguese man-o’-war (Physalia physalis). -
OPEN LETTER Joel K. Manby President, CEO, and Director
OPEN LETTER Joel K. Manby President, CEO, and Director SeaWorld Parks & Entertainment 9205 South Park Center Loop, #400 Orlando, FL 32819 Dear Mr. Manby, On behalf of our more than 6.5 million members and supporters, our organizations are writing this open letter to you to request the voluntary release of the necropsy (animal autopsy) report and clinical history for Tilikum to the National Marine Fisheries Service (NMFS), the federal agency responsible for the conservation and management of marine mammals. Marine-mammal exhibition facilities such as SeaWorld are required to obtain permits to capture from the wild or import marine mammals for public display under the U.S. Marine Mammal Protection Act (MMPA), which was passed in 1972. When Tilikum was first imported into the United States in 1992, these permits contained special conditions established by the NMFS. In his case, this included a standard requirement to submit his necropsy and clinical history results to the NMFS when he eventually passed away. These conditions also apply to his progeny, including his granddaughter Kyara, who died of suspected pneumonia on July 24th at SeaWorld San Antonio at only 3 months of age, and at least eight other offspring who are still alive today. We strongly urge SeaWorld not only to comply with this legal requirement but also to adopt this standard voluntarily for all cetaceans in its care. In doing so, SeaWorld would set an admirable and progressive industry standard and satisfy the strong public interest in the health and welfare of these animals. Indeed, reasonable transparency regarding health records is essential to legitimate marine-animal rescue and rehabilitation work, a role that SeaWorld claims is integral to its mission. -
A Guide to Harmful and Toxic Creatures in the Goa of Jordan
Published by the Royal Marine Conservation Society of Jordan. P. O. Box 831051, Abdel Aziz El Thaalbi St., Shmesani 11183. Amman Copyright: © The Royal Marine Conservation Society of Jordan Reproduction of this publication for educational and other non- commercial purposes is authorized without prior written approval from the copyright holder provided the source is fully acknowledged. ISBN: 978-9957-8740-1-8 Deposit Number at the National Library: 2619/6/2016 Citation: Eid, E and Al Tawaha, M. (2016). A Guide to Harmful and Toxic Creature in the Gulf of Aqaba of Jordan. The Royal Marine Conservation Society of Jordan. ISBN: 978-9957-8740-1-8. Pp 84. Material was reviewed by Dr Nidal Al Oran, International Research Center for Water, Environment and Energy\ Al Balqa’ Applied University,and Dr. Omar Attum from Indiana University Southeast at the United State of America. Cover page: Vlad61; Shutterstock Library All photographs used in this publication remain the property of the original copyright holder, and it should not be reproduced or used in other contexts without permission. 1 Content Index of Creatures Described in this Guide ......................................................... 5 Preface ................................................................................................................ 6 Part One: Introduction ......................................................................................... 8 1.1 The Gulf of Aqaba; Jordan ......................................................................... 8 1.2 Aqaba; -
Seaworld San Diego to Offer More Than 100 Craft Beers at All-New Craft Beer Festival
SEAWORLD SAN DIEGO TO OFFER MORE THAN 100 CRAFT BEERS AT ALL-NEW CRAFT BEER FESTIVAL Each weekend, park guests can toast to outdoor fun with beer, tasty bites, live music, fireworks, and park admission tickets as low as $49.99. SAN DIEGO, CA (August 6, 2021): SeaWorld San Diego is bringing hops to roller coaster drops for the remainder of summer with an all-new Craft Beer Festival that’s safely spread out across more than 100 acres of expansive open-air grounds of the theme park. The festival will feature more than 100 craft beers, wines, seltzers, and cocktails with an impressive mix of domestic, international, and local California favorites. The event will be hosted on Saturdays and Sundays from August 14 through September 19 providing guests with plenty of brews, beverages, and bites spread out between 12 locations throughout the park, plus festive entertainment to keep the party going all day long. “We’re excited to kick-off our first-ever craft beer festival at SeaWorld San Diego. We’re a place that is designed for fun and entertainment and it’s a natural fit to expand our beverage offerings and highlight local craft beers and beyond and provide our guests an expansive assortment of beer and other drink options to choose from all in one place,” said John Dunlap, SeaWorld San Diego Park President. “People are looking for fun and safe ways to spend their last days of summer. With an open-air environment, this event is a great way to end summer with delicious food and drink choices, live music, and to finish it all off – fireworks.” Cheers to Beer! Among the beers on tap are varieties of local San Diego favorite craft brewers including Alesmith Brewing Company, Ballast Point Brewing Company, Harland Brewing Modern Times, Mother Earth Brew Co., Pizza Port, Societe Brewing, Stone Brewing, and Thorn Brewing Co.