Three-Dimensional Modeling of the Human Jaw/Teeth Using Optics and Statistics
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Microbial Biogeography and Ecology of the Mouth and Implications for Periodontal
bioRxiv preprint doi: https://doi.org/10.1101/541052; this version posted February 8, 2019. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. This article is a US Government work. It is not subject to copyright under 17 USC 105 and is also made available for use under a CC0 license. Microbial biogeography and ecology of the mouth and implications for periodontal diseases Authors: Diana M. Proctor1,2,10, Katie M. Shelef3,10, Antonio Gonzalez4, Clara L. Davis Long5, Les Dethlefsen1, Adam Burns1, Peter M. Loomer6, Gary C. Armitage7, Mark I. Ryder7, Meredith E. Millman7, Rob Knight4, Susan P. Holmes8, David A. Relman1,5,9 Affiliations 1Division of Infectious Disease & Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305 USA 2National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892 USA 3Department of Biology, Stanford University School of Medicine, Stanford, CA 94305 USA 4Departments of Pediatrics and Computer Science and Engineering, University of California at San Diego, La Jolla, CA 92093 USA 5Department of Microbiology & Immunology, Stanford University School of Medicine, Stanford, CA 94305 USA 6Ashman Department of Periodontology & Implant Dentistry, New York University College of Dentistry, New York, NY 10010 USA 7Division of Periodontology, University of California, San Francisco School of Dentistry, San Francisco, CA 94143 USA 8Department of Statistics, Stanford University, Stanford, CA 94305 USA 9Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304 USA 10These authors contributed equally Corresponding author: David A. Relman: [email protected]; Address: Encina E209, 616 Serra Street, Stanford, California 94305-6165; Phone: 650-736-6822; Fax: 650-852-3291 1 bioRxiv preprint doi: https://doi.org/10.1101/541052; this version posted February 8, 2019. -
Dynamic Evaluation of Forces During Mastication
Project Number: ME-SYS-0787 Dynamic Evaluation of Forces During Mastication A Major Qualifying Project Submitted to the Faculty of WORCESTER POLYTECHNIC INSTITUTE In partial fulfillment of requirements for the Degree of Bachelor of Science By Justin McGarry Anthony Spangenberger Date: Approval: Professor Satya Shivkumar, Advisor Abstract A reproduction of the human masticatory system is presented here to evaluate mechanical properties of foods, relevant design elements of the simulator, and the overall practicality of the system. The model incorporates a cam-driven linkage system providing realistic motion of the mandible, with reaction forces measured by strain gages on two axes to record real time changes in food structure. The experiment demonstrates that the construction of a mastication simulator is feasible and allows texture profiling and discrimination between similar foods. i Acknowledgements Our MQP was completed with the help of several individuals who offered professional advice and technical guidance. We would like to thank Prof. Satya Shivkumar, our project advisor, for guiding us with his extensive knowledge of materials and testing procedures, Prof. John Hall for his help with the sensors used in this project and his willingness to lend some of the necessary equipment, Prof. Robert Norton for his advice on the fixture design, Fred Hutson for lending equipment from the physics department for use in calibration of the fixture, Randy Robinson for the computer used for recording data, Neil Whitehouse, Toby Bergstrom, and Adam -
Structural Changes in the Oral Microbiome of the Adolescent
www.nature.com/scientificreports OPEN Structural changes in the oral microbiome of the adolescent patients with moderate or severe dental fuorosis Qian Wang1,2, Xuelan Chen1,4, Huan Hu2, Xiaoyuan Wei3, Xiaofan Wang3, Zehui Peng4, Rui Ma4, Qian Zhao4, Jiangchao Zhao3*, Jianguo Liu1* & Feilong Deng1,2,3* Dental fuorosis is a very prevalent endemic disease. Although oral microbiome has been reported to correlate with diferent oral diseases, there appears to be an absence of research recognizing any relationship between the severity of dental fuorosis and the oral microbiome. To this end, we investigated the changes in oral microbial community structure and identifed bacterial species associated with moderate and severe dental fuorosis. Salivary samples of 42 individuals, assigned into Healthy (N = 9), Mild (N = 14) and Moderate/Severe (M&S, N = 19), were investigated using the V4 region of 16S rRNA gene. The oral microbial community structure based on Bray Curtis and Weighted Unifrac were signifcantly changed in the M&S group compared with both of Healthy and Mild. As the predominant phyla, Firmicutes and Bacteroidetes showed variation in the relative abundance among groups. The Firmicutes/Bacteroidetes (F/B) ratio was signifcantly higher in the M&S group. LEfSe analysis was used to identify diferentially represented taxa at the species level. Several genera such as Streptococcus mitis, Gemella parahaemolysans, Lactococcus lactis, and Fusobacterium nucleatum, were signifcantly more abundant in patients with moderate/severe dental fuorosis, while Prevotella melaninogenica and Schaalia odontolytica were enriched in the Healthy group. In conclusion, our study indicates oral microbiome shift in patients with moderate/severe dental fuorosis. -
UCDH Dental Hygiene Glossary Editorial Compilation/Consultant Special Thanks
UCDH Dental Hygiene Glossary A Faculty/Student Venture Editorial Compilation/Consultant Brent Molen RDH, Med College President/Chief Operations Officer Assistant Professor, The Utah College of Dental Hygiene at Careers Unlimited Special Thanks A special thanks goes out to all the dental hygiene students of the classes of 2009, 2010, and 2011 who have helped make this venture possible and who have contributed their efforts to it. The information contained in this glossary is to be used by the dental hygiene professional only and for dental education purposes only. It is not intended for the general public. Any sale, distribution, copying, dissemination, or duplication of this glossary without written permission is strictly prohibited. If you have received this glossary electronically in error, please call (801) 426-8234 (USA) or notify by return email [email protected] immediately & delete or destroy the digital file. Copyright 2010 Careers Unlimited L.L.C. UCDH is a division of Careers Unlimited L.L.C. Abducens Nerve: the sixth cranial nerve, which controls movement of one single muscle, the lateral rectus muscle, of the eye. Abrasive: to scratch a surface or have rough texture being able to remove a layer. Abscess: the destruction of tissue due to activity of bacteria producing pus, pain and swelling as result of microscopic cellular activity. Abuse: to do harm or wrong doing to others or yourself; by physical or chemical means. Abutment: a tooth, root or implant that serves as the support or anchor to a denture or a fixed or removable bridge. See pontics. Abutment: a tooth, root, or implant that supports and maintains position of a fixed or removable prosthesis. -
Forensic Archaeology & Forensic Anthropology
Forensic Archaeology & Forensic Anthropology ADJ14 Advanced Criminal Investigations Anthropology & Archaeology ´ Anthropology is the study of the biological and cultural aspects of all humans in all places in all times. ´ Archaeology is the study of human history and prehistory through the excavation of sites and the analysis of artifacts and other physical remains. Introduction to Forensic Archaeology & Forensic Anthropology ´ Forensic Anthropology is the field of study that deals with the analysis of human skeletal remains resulting from unexplained deaths. Experts in the discipline, because of their understanding of skeletal biology, examine human bones with the goal of extracting information about persons represented by skeletal remains and circumstances surrounding death (Byers, 2011). ´ Forensic Archaeology is a subfield of forensic anthropology, and forensic archaeology is the forensic application of archaeological techniques. Archaeology is the study of humans, both modern and ancient. Specifically, forensic archeologists perform the controlled recovery of human remains and other evidence at forensic scenes. Proper archeological procedures generally require significant time and attention to detail, and so the process may seem rather slow to investigators. However, the end result of this effort is the ability to exactly reconstruct the entire scene as it appeared before excavation (Nawracki, 1996). Forensic Anthropology ´ Forensic anthropologists attempt to accomplish 5 main objectives in their work: ① When soft tissue has deteriorated to the point that demographic characteristics of a body cannot be determined by visual inspection, they attempt to determine ancestry, sex, age, and living height from the skeleton. ② When there is evidence of traumatic injury (bullet holes, stab wounds, fractures) to human bone, forensic anthropologists attempt to identify the nature of the traumas and their causative agent pertaining to cause and manner of death. -
3-D Surface Anthropometry: Review of Technologies (L'hthropodtrie De Surface-En Trois Dimensions: Examen Des Technologies)
I 1 n A L 1 W ADVISORY QROUP FOR AEROSPACE RE(KARCH & DEVELOPMENT 7 RUE ANCEUE, 92200 NEUIUY-SUR-SEINE, FRANCE 3-D Surface Anthropometry: Review of Technologies (l'hthropodtrie de surface-en trois dimensions: examen des technologies) . \ AGARD-AR-329 I I ADVISORY GROUP FOR AEROSPACE RESEARCH & DEVELOPMENT 7 RUE ANCELLE, 92200 NEUILLY-SUR-SEINE, FRANCE AGARD ADVISORY REPORT 329 I- I. 3-D Surface Anthropometry: Review of Technologies (1'AnthropomCtrie de surface en trois dimensions: examen des technologies) Editors: K.M. Robinette (US), M.W. Vannier (US), M. Rioux (CA), P.R.M. Jones (UK) This Advisory Report was prepared by Working Group 20 of the Aerospace Medical Panel of AGARD. North Atlantic Treaty Organization Organisation du Traite de I'Atlantique Nord I The Mission of AGARD According to its Charter, the mission of AGARD is to bring together the leading personalities of the NATO nations in the fields of science and technology relating to aerospace for the following purposes: - Recommending effective ways for the member nations to use their research and development capabilities for the common benefit of the NATO community; - Providing scientific and technical advice and assistance to the Military Committee in the field of aerospace research and development (with particular regard to its military application); - Continuously stimulating advances in the aerospace sciences relevant to strengthening the common defence posture; - Improving the co-operation among member nations in aerospace research and development;, - Exchange of scientific and technical information; - Providing assistance to member nations for the purpose of increasing their scientific and technical potential; - Rendering scientific and technical assistance, as requested, to other NATO bodies and to member nations in connection with research and development problems in the aerospace field. -
Study of Root Canal Anatomy in Human Permanent Teeth
Brazilian Dental Journal (2015) 26(5): 530-536 ISSN 0103-6440 http://dx.doi.org/10.1590/0103-6440201302448 1Department of Stomatologic Study of Root Canal Anatomy in Human Sciences, UFG - Federal University of Goiás, Goiânia, GO, Brazil Permanent Teeth in A Subpopulation 2Department of Radiology, School of Dentistry, UNIC - University of Brazil’s Center Region Using Cone- of Cuiabá, Cuiabá, MT, Brazil 3Department of Restorative Dentistry, School of Dentistry of Ribeirão Beam Computed Tomography - Part 1 Preto, USP - University of São Paulo, Ribeirão Preto, SP, Brazil Carlos Estrela1, Mike R. Bueno2, Gabriela S. Couto1, Luiz Eduardo G Rabelo1, Correspondence: Prof. Dr. Carlos 1 3 3 Estrela, Praça Universitária s/n, Setor Ana Helena G. Alencar , Ricardo Gariba Silva ,Jesus Djalma Pécora ,Manoel Universitário, 74605-220 Goiânia, 3 Damião Sousa-Neto GO, Brasil. Tel.: +55-62-3209-6254. e-mail: [email protected] The aim of this study was to evaluate the frequency of roots, root canals and apical foramina in human permanent teeth using cone beam computed tomography (CBCT). CBCT images of 1,400 teeth from database previously evaluated were used to determine the frequency of number of roots, root canals and apical foramina. All teeth were evaluated by preview of the planes sagittal, axial, and coronal. Navigation in axial slices of 0.1 mm/0.1 mm followed the coronal to apical direction, as well as the apical to coronal direction. Two examiners assessed all CBCT images. Statistical data were analyzed including frequency distribution and cross-tabulation. The highest frequency of four root canals and four apical foramina was found in maxillary first molars (76%, 33%, respectively), followed by maxillary second molars (41%, 25%, respectively). -
Cell Proliferation Study in Human Tooth Germs
Cell proliferation study in human tooth germs Vanesa Pereira-Prado1, Gabriela Vigil-Bastitta2, Estefania Sicco3, Ronell Bologna-Molina4, Gabriel Tapia-Repetto5 DOI: 10.22592/ode2018n32a10 Abstract The aim of this study was to determine the expression of MCM4-5-6 in human tooth germs in the bell stage. Materials and methods: Histological samples were collected from four fetal maxillae placed in paraffin at the block archive of the Histology Department of the School of Dentistry, UdelaR. Sections were made for HE routine technique and for immunohistochemistry technique for MCM4-5-6. Results: Different regions of the enamel organ showed 100% positivity in the intermediate layer, a variation from 100% to 0% in the inner epithelium from the cervical loop to the incisal area, and 0% in the stellar reticulum as well as the outer epithelium. Conclusions: The results show and confirm the proliferative action of the different areas of the enamel organ. Keywords: MCM4, MCM5, MCM6, tooth germ, cell proliferation. 1 Molecular Pathology in Stomatology, School of Dentistry, Universidad de la República, Montevideo, Uruguay. ORCID: 0000-0001- 7747-671 2 Molecular Pathology in Stomatology, School of Dentistry, Universidad de la República, Montevideo, Uruguay. ORCID: 0000-0002- 0617-1279 3 Molecular Pathology in Stomatology, School of Dentistry, Universidad de la República, Montevideo, Uruguay. ORCID: 0000-0003- 1137-6866 4 Molecular Pathology in Stomatology, School of Dentistry, Universidad de la República, Montevideo, Uruguay. ORCID: 0000-0001- 9755-4779 5 Histology Department, School of Dentistry, Universidad de la República, Montevideo, Uruguay. ORCID: 0000-0003-4563-9142 78 Odontoestomatología. Vol. XX - Nº 32 - Diciembre 2018 Introduction that all the DNA is replicated (12), and prevents DNA from replicating more than once in the Tooth organogenesis is a process involving a same cell cycle (13). -
GRAS 45BC KEMAR Head & Torso with Mouth Simulator, Non-Configured
GRAS 45BC KEMAR Head & Torso with Mouth Simulator, Non-configured Connection: 0 V/CCP or 200 V/LEMO The 45BC KEMAR head & torso with mouth simulator is Channel(s): 2 an acoustic research tool with built-in ear and mouth ANSI: S3.36, S3.25 simulators that simulates the changes that occur to IEC: 60318-7 soundwaves as they pass a human head and torso. Its Special feature: Built-in mouth simulator and equivalent without mouth is GRAS 45BB KEMAR Head & power amplifier Torso, non-configured. GRAS Sound & Vibration Skovlytoften 33, 2840 Holte, Denmark www.grasacoustics.com GRAS 45BC KEMAR Head & Torso with Page: 2 Technology Mouth Simulator, Non-configured Introduction and in the far-field. Because of its anthropometric shape, it does so more realistically than any other The KEMAR head and torso simulator was manikin. KEMAR is the only manikin with a introduced by Knowles in 1972 and quickly became changeable ear-to-shoulder ratio simulating both the industry standard for hearing-aid manufacturers male and female median values. and research audiologists (visit KEMAR.us to read the full story). The GRAS KEMAR has the same Mouth Simulator dimensions and acoustical properties as the original The built-in mouth simulator simulates the sound KEMAR from 1972 and is 100% backward compatible. field around the human head at close quarters and When fitted with pinna simulators, ear canal the far-field. It is based on ITU-T Rec. P.58. At the extension, and Ear Simulator, according to IEC mouth reference point (MRP) – 25 mm from the lip 60318-4 or low-noise, KEMAR closely mimics the plane – the mouth simulator can be equalized to acoustic properties of the human ear. -
Infectious Complications of Dental and Periodontal Diseases in the Elderly Population
INVITED ARTICLE AGING AND INFECTIOUS DISEASES Thomas T. Yoshikawa, Section Editor Infectious Complications of Dental and Periodontal Diseases in the Elderly Population Kenneth Shay Geriatrics and Extended Care Service Line, Veterans Integrated Services Network 11, Geriatric Research Education and Clinical Center and Dental Service, Ann Arbor Downloaded from https://academic.oup.com/cid/article/34/9/1215/463157 by guest on 02 October 2021 Veterans Affairs Healthcare System, and University of Michigan School of Dentistry, Ann Arbor Retention of teeth into advanced age makes caries and periodontitis lifelong concerns. Dental caries occurs when acidic metabolites of oral streptococci dissolve enamel and dentin. Dissolution progresses to cavitation and, if untreated, to bacterial invasion of dental pulp, whereby oral bacteria access the bloodstream. Oral organisms have been linked to infections of the endocardium, meninges, mediastinum, vertebrae, hepatobiliary system, and prosthetic joints. Periodontitis is a pathogen- specific, lytic inflammatory reaction to dental plaque that degrades the tooth attachment. Periodontal disease is more severe and less readily controlled in people with diabetes; impaired glycemic control may exacerbate host response. Aspiration of oropharyngeal (including periodontal) pathogens is the dominant cause of nursing home–acquired pneumonia; factors reflecting poor oral health strongly correlate with increased risk of developing aspiration pneumonia. Bloodborne peri- odontopathic organisms may play a role in atherosclerosis. Daily oral hygiene practice and receipt of regular dental care are cost-effective means for minimizing morbidity of oral infections and their nonoral sequelae. More than 300 individual cultivable species of microbes have growing importance in the elderly population. In 1957, nearly been identified in the human mouth [1], with an estimated 1014 70% of the US population aged 175 years had no natural teeth. -
The Heterogeneity Ofsmall Sculptures on Easter Island Before 1886
The Heterogeneity ofSmall Sculptures on Easter Island before 1886 Received 4 October 1979 THOR HEYERDAHL ASTER ISLAND ART has a unique reputation for its sophisticated originality but also for its repetitious monotony. An ethnologist, art student, or dealer is expected to E recognize any sculpture in stone or wood from Easter Island and identify it by its proper Rapanui name as a moai kavakava, moai papa, rei miro, tahonga, ua, and so on. It therefore came as a great surprise to the scientific world when Lavachery (1939), during the Franco-Belgian Expedition to Easter Island in 1934, discovered such a quantity ofhet erogeneous petroglyphs all over the barren landscape that he, as the only archaeologist of the expedition, devoted all his fieldwork to the study and registration ofthis so far totally overlooked aspect ofEaster Island art. It follows that Lavachery would be among the first to come to Oslo to inspect the nearly 1000 stone carvings obtained from various families on the island by the Norwegian Ar chaeological Expedition shortly before departure in 1956. How many of them were an cient, and, if new, what did they reflect oflocal motifs and old traditions? Perhaps Lava chery was better prepared than anyone else for this new explosion ofEaster Island art. His findings two decades earlier of an exuberance of art motifs nonexistent on the island ex cept where they were carved on immovable rock was to him a forewarning that the secretive and superstitious population might have carried into security all such portable objects as would have been stolen or destroyed ifleft about. -
Digestive System (Part-I)
NPTEL – Basic Courses – Basic Biology Lecture 11: Digestive System (Part-I) Introduction: The collective processes by which a living organism takes food which are necessary for their growth, maintenance and energy needs is called nutrition. The chemical substances present in the food are called nutrients. DIFFERENT MODE OF NUTRITION IN ORGANISMS: It is important to know the different modes of nutrition in all living organisms in order to understand energy flow within the ecosystem. Plant produces high energy organic food from inorganic raw materials. They are called autotroph and the mode of nutrition is known as autotrophic nutrition. Animals feed on those high energy organic food, are called as heterotrophs and their mode of nutrition is known as heterotrophic nutrition Heterotrophic nutrition further sub-categorise in holozoic, parasitic, and saprophytic mode of nutrition based on the pattern and class of food that is taken inside. Holozoic Nutrition: It involves taking entire organic food and this can be in the form of whole part of plant or animal. Most of the free living protozoans, humans and other animals fall under this category. Saprophytic Nutrition: The organism fulfils the requirement of food from the rotten parts of dead organisms and decaying matter. The organisms secrete digestive enzymes outside the body on their food and then take in digested food. It is a kind of extra-cellular digestion. Examples: Housefly, Spiders etc. Parasitic Nutrition: The organism fulfils the requirement of food from the body of another organism. The parasites are of two distinct types, one which lives inside the host and the other which lives outside.