XXVI ISTH Congress and 63rd Annual SSC Meeting LOREM IPSUM DOLOR LOREM IPSUM DOLOR XXVI ISTH Congress and 63rd Annual SSC Meeting FINAL PROGRAM www.isth2017.org 1 XXVI ISTH Congress and 63rd Annual SSC Meeting XXVI ISTH Congress and 63rd Annual SSC Meeting LOREM IPSUM DOLOR TABLE OF CONTENTS LOREM IPSUM DOLOR July 2017 VOLUME 11 | NUMBER 7 Editor in Chief: Mary Cushman Invitation and Welcome Messages 4–9 Congress Information ISTH 2017 Committees 10–13 ISTH 2017 Abstract Reviewers 14–18 Venue and Contacts 492 ISTH Council 19 Venue Floor Plans 494–503 ISTH SSC Committees 20 ISTH 2017 Attendee Services ISTH Awards 23 and Innovations 504–507 ISTH and ISTH 2017 Awards 24 Congress Information 508–513 ISTH 2017 Awards 25–27 ISTH 2017 Networking Events 515 About the ISTH 28–29 ISTH 2017 5K Charity Run/Walk 516 Local Information 518 A new open access Transportation in Berlin 519 Program journal from ISTH Program Overview 32–34 Supported Symposia and Program Day by Day 36–47 Product Theater Overview and Listing July 2017 Editor in Chief: Mary Cushman VOLUME 11 | NUMBER 7 Peer-Reviewed Open Access Journal Editor in Chief: Mary Cushman SSC and Educational Program 50–83 Now Open for Submissions Special Sessions 86–87 Exhibition and Congress Support 523 In this issue Nurses Forum 90–96 Supported Symposia Thrombotic complications of myeloproliferative neoplasms Research and Practice in Master Classes and and Product Theater Presentations 526–537 New recombinant FVIIa: pharmacokinetics and Career Development Sessions 98–108 efficacy Thrombosis and Haemostasis Crystal structure of an ADAMTS13 mutant (RPTH) is an exciting new open www.rpth.isth.org Exhibition and Exhibitors ISSN 2475-0379 access journal from the Scientific Program International Society on Exhibition Floor Plan 540–543 Thrombosis and Haemostasis Sunday, July 9, 2017 110 Exhibitior & Supporter List 544–549 (ISTH) for innovative science and Monday, July 10, 2017 112–146 Company Profiles 550–579 @RPTHjournal discourse among researchers, Tuesday, July 11, 2017 148–185 Corporate Meeting Suites 580–581 clinicians and patients in the global Wednesday, July 12, 2017 187–213 Conflict of Interest thrombosis and hematology Thursday, July 13, 2017 215–228 Disclosure Information 582–583 Mary Cushman, M.D., M.Sc. community. In an ever-changing Editor-in-Chief environment, RPTH offers an exciting medium for rigorous yet Posters Authors Index rapid peer review and immediate dissemination of research. Monday, July 10, 2017 230–311 Authors Index 586–604 The journal will publish basic, translational, clinical, Tuesday, July 11, 2017 312–400 population and implementation research in thrombosis, Wednesday, July 12, 2017 401–482 Future ISTH Meetings hemostasis, vascular disease and related areas with an aim Publication Only 483–488 and Congresses 605 Join the Conversation! to advance the treatment of patients. Paper types covered by RPTH: original science, review articles on recent advances, debates, synthesis articles on isth.org research translation to practice and compelling case reports. The ISTH is a global not-for-profit Username: ISTH2017 Password: sobibivv organization advancing the The call for submissions to RPTH is now open. WIFI understanding, prevention, diagnosis and treatment of Visit RPTH.ISTH.ORG to get started today! thrombotic2 and bleeding disorders. Questions? Contact us at +1 919 929 3807 3 XXVI ISTH Congress and 63rd Annual SSC Meeting XXVI ISTH Congress and 63rd Annual SSC Meeting INVITATION AND WELCOME MESSAGE WELCOME MESSAGE Dear ISTH 2017 Congress participants, We are grateful to our industry partners for their generous support of the congress. We encourage you to visit the exhibition hall, attend product theater and supported symposia, learn about the latest We are pleased to welcome you to the XXVI International Society on Thrombosis and Haemostasis diagnostic and therapeutic advances available to us and exchange ideas with representatives from the (ISTH) Congress and 63rd Annual Scientific and Standardization Committee (SSC) Meeting in Berlin, diagnostic and pharmaceutical industry. a city full of life with a distinctive culture and cosmopolitan blend of people and events. On Wednesday evening, we invite you to attend the networking evening at the famous Tempodrom in Founded in the 13th century, Berlin has experienced an eventful history, with frequent and radical downtown Berlin with live music and delicious catering by Sarah Wiener, a famous Austrian chef now changes over the years that have continually transformed the city. Once divided by a wall for decades, living in Berlin. Make sure you purchase tickets to attend before it is sold out! Berlin is now seen as a global symbol for unity and a vibrant metropolis in the heart of Europe. The congress closes on Thursday at noon with a session on the highlights of ISTH 2017, where you We are proud to host the congress for the first time in Berlin, Germany, after nearly 37 years follo- will hear a recap of selected, top-scoring presentations from both basic and clinical science. wing the inaugural ISTH congress, which was hosted in Montreux, Switzerland, in 1970. With the developments that have occurred in the field of thrombosis and hemostasis over the decades, this Finally we are excited about the many new innovations that will be introduced at the congress. Be year’s congress motto truly hits the mark: “Transcending Scientific Boundaries.” Here at ISTH 2017, sure to download the ISTH 2017 mobile app and stay up to date and build your itinerary for the we are excited to welcome more than 8,000 scientists and clinicians from around the world focused meeting. in thrombosis and hemostasis who have the ambition and drive to push scientific boundaries in the field. We wish you an informative and memorable experience at ISTH 2017. We hope you will be inspired by the science, news, and innovation taking place at the congress, as well as by the culture of Berlin Saturday and the first half of Sunday are devoted to the 63rd Annual ISTH SSC Meeting. Work in and its history. progress, preliminary or final reports from the multitude of projects of the SSC, mixed with a wide variety of educational lectures focus on the critically important diagnostic and therapeutic standards, disease nomenclature, and classification that allow the field to work together toward real-time and patient-centric solutions. The XXVI ISTH Congress kicks off with the opening ceremony on Sunday evening. We look forward to sharing a taste of history in medicine and science mixed with modern artists and music, which illustrates the river of knowledge. The opening ceremony will be followed by a networking reception in the exhibition halls. The scientific part of the congress features 131 invited speakers, including eight plenary lectures by front-line scientists and 84 state-of-the-art lectures by leaders in their respective fields (accompa- nied by selected state-of-the-art papers in the Journal of Thrombosis and Haemostasis). The congress also offers 39 abstract symposia with an introductory review lecture, followed by oral presentations of top-scoring abstracts. A late-breaking session will be held on Tuesday highlighting important and timely results from clinical trials. From Monday to Wednesday, poster sessions will be presented. For those who have reserved tickets, there are master classes covering 40 topics in the early mornings between Sunday to Wednesday, and career development sessions for small groups will be held from Monday to Wednesday at lunch time. Overall, more than 3,000 abstracts will be presented as oral or poster presentations. Johannes Oldenburg, M.D. Ingrid Pabinger, M.D. Walter Ageno, M.D. During the lunch break, you have the opportunity to discuss poster presentations in the poster area ISTH XXVI Congress President ISTH Council Chair ISTH SSC Chair and network with your colleagues followed by industry supported product theater presentations and supported symposia. 4 5 XXVI ISTH Congress and 63rd Annual SSC Meeting XXVI ISTH Congress and 63rd Annual SSC Meeting WELCOME MESSAGE WELCOME MESSAGE With this year's Congress, the title of which is "Transcending Scientific Boundaries," you are once Dear Participants of the ISTH 2017 Congress, again sending out an important signal with regard to global and cross-border advances in the pre- vention and treatment of thrombosis, blood coagulation disorders and related secondary diseases. Welcome to Berlin! Over 9,000 experts from 90 countries will be coming together at this event to report both on the latest scientific findings and their experience. They will be providing insights into the current state of I am delighted that you are holding this prestigious congress in Germany for the first time and have research and identifying possibilities for further improving the life of patients the world over. Further- chosen Berlin as your venue. Experts from all over the world will gather here to explore the latest more, with your guidelines and the valuable recommendations on diagnosis and therapy that go with findings on endemic cardiovascular diseases. them, you are supporting family doctors and specialists in providing the best possible treatment for their patients. As one of the world’s leading trade show and congress venues, Berlin offers ideal conditions for professional meetings. At the same time, as a modern health care capital with a long history, our I wish to express my sincere gratitude for your untiring efforts in the further development of the city boasts an excellent scientific landscape. Along with Charité-Universitätsmedizin Berlin, Berlin’s prevention, diagnosis and treatment of thrombosis and blood coagulation disorders, as well as the se- flagship of modern medical research and practice, you will find a broad spectrum of public and pri- condary diseases that might accompany them. For this year's conference of the International Society vate hospitals, excellent colleges and universities, and a host of renowned non-university research of Thrombosis and Haemostasis, which is taking place in Germany for the first time this year, I wish institutes doing cutting-edge research.