Rezultate preliminare PCCA 2011/2012 Proiecte de tip 2 DC 4 - Sănătate

Nume Prenume Nr. Cod director de director Titlu proiect Institutie coordonatoare Punctaj Crt depunere proiect de proiect

PN-II-PT-PCCA- IMAGE AND ELECTROMAGNETIC GUIDED INNOVATIVE 1 Lucian Gruionu MEDINSYS 91.67 2011-3.2-0482 SYSTEM FOR TRANSBRONCHIAL BIOPSY National Institute of Research and PN-II-PT-PCCA- Investigation of viral and host markers of non-response to 2 Oprisan Gabriela Rodica Development in Microbiology and 90.25 2011-3.2-1150 anti-viral treatment in chronic hepatitis C Immunology “Cantacuzino"

GENOMEWIDE STUDY OF BIPOLAR I DISORDER AND PN-II-PT-PCCA- SPITALUL CLINIC DE PSIHIATRIE PROF DR. 3 Serbanescu Maria GUIDE FOR ASSESSING THE GENETIC RISK FOR BIPOLAR I 90.00 2011-3.2-1628 ALEXANDRU OBREGIA DISORDER IN THE ROMANIAN POPULATION

PN-II-PT-PCCA- Role of S100A4 and MAP4K4 in pancreatic ductal 4 popescu irinel FUNDENI CLINICAL INSTITUTE 88.33 2011-3.2-1490 adenocarcinoma progression

PN-II-PT-PCCA- Real Time quantitative PCR evaluation of differentiation, National Institute of Research and Diagnosis 5 Giovanni Bussolati 87.33 2011-3.2-0623 drug sensitivity and prognosis of endocrine tumors. Victor Babes

PN-II-PT-PCCA- Advanced strategies for high performance indoor Universitatea Tehnica de Constructii 6 Nastase Ilinca 87.00 2011-3.2-1212 Environmental QUAliTy in Operating Rooms Bucuresti

PROTEOMICS AND METABOLOMICS IN DIAGNOSIS AND PN-II-PT-PCCA- 7 VOICULESCU MIHAI SCORING OF VASCULAR CALCIFICATIONS IN CHRONIC INSTITUTUL CLINIC FUNDENI 86.25 2011-3.2-0794 RENAL FAILURE

Novel nanostructured prosthetic tubular devices with PN-II-PT-PCCA- 8 Ficai Anton antibacterial and antibiofilm properties induced by physico- University Politehnica of Bucharest 86.00 2011-3.2-0284 chemical and morphological changes

Development and preclinical evaluation of nanoparticulate PN-II-PT-PCCA- Universitatea de Medicina si Farmacie ”Iuliu 9 Vlase Laurian drug delivery systems for targeted antitumor therapy of 85.33 2011-3.2-1060 Hatieganu” colorectal cancer

Page 1 of 6 Nume Prenume Nr. Cod director de director Titlu proiect Institutie coordonatoare Punctaj Crt depunere proiect de proiect

Analysis of microRNA biomarkers as predictive values for PN-II-PT-PCCA- 10 Balacescu Ovidiu cervical cancer treatment, in relationship with The Oncology Institute „Prof.Dr.I.Chiricuta” 85.00 2011-3.2-1328 environmental exposure to arsenic, phthalates and ETS.

Validation of siRNA technology for the silencing of microglial PN-II-PT-PCCA- 11 Ristoiu Violeta Paula targets significant for neuropathic pain and Alzheimer 84.67 2011-3.2-0086 disease BIOMARKER PANEL DESIGN FOR INDIVIDUALIZED PN-II-PT-PCCA- PREDICTION OF THE THERAPEUTIC RESPONSE IN 12 Baicus Cristian Spitalul Clinic Colentina 84.00 2011-3.2-0221 CHRONIC HEPATITIS C, BASED ON AN INTEGRATED BIOINFORMATICS APPROACH PN-II-PT-PCCA- Coagulation disorders in subclinical hypothyroidism. Clinical 13 Dermengiu Dan National Institute of Legal Medicine 83.25 2011-3.2-0500 and medical-legal consequences

PN-II-PT-PCCA- New biodegradable scaffold materials for bone 14 Furtos Gabriel Babes Bolyai University, Cluj-Napoca 83.25 2011-3.2-1654 reconstruction Study of pathogenicity and virulence markers of influenza “Cantacuzino” National Institute for PN-II-PT-PCCA- virus in adults and children with severe acute respiratory 15 Radu Dorel Research and Development in Microbiology 82.67 2011-3.2-0677 infection, correlated with immune host response and clinical and Immunology evolution Neurogenic detrusor overactivity treated with Botulinum PN-II-PT-PCCA- 16 Antochi Florina Anca Toxin A (BTX-A) and Neuromodulation, urodynamic and Fundatia "Prof.Dr.Dimitrie Gerota" 82.67 2011-3.2-1241 quality of life PN-II-PT-PCCA- Development of a New Screening Tool for Viral and Universitatea de Medicina si Farmacie “Carol 17 Mischianu Dan Liviu Dorel 82.33 2011-3.2-0933 Molecular Markers in Prostate Cancer Davila”

PN-II-PT-PCCA- Production and characterization of phytomolecules with 18 Cucu Daniela Universitatea din Bucuresti 82.00 2011-3.2-0201 antiviral activity against hepatitis B and C viruses

PN-II-PT-PCCA- 19 PETRESCU Barbu-Serban BRAIN AND ELECTROSTIMULATION INDUCED MOVEMENT S.C. NEURON GROUP SRL 81.75 2011-3.2-1265 Implementation of a complex genome profiling diagnostic PN-II-PT-PCCA- 20 Diaconu Carmen Cristina algorithm for patients with congenital and developmental Stefan S. Nicolau Institute of Virology 81.50 2011-3.2-1675 abnormalities EVALUATION OF DRUGS AND NANOSTRUCTURED DRUG PN-II-PT-PCCA- SYSTEMS EFFECTS ON PLATELET AND ERYTHROCYTE Universitatea de Medicina si Farmacie "Carol 21 MIRCIOIU CONSTANTIN 80.75 2011-3.2-1773 AGGREGATION FOR INDIVIDUALIZATION OF Davila" Bucuresti ANTIAGGREGANT THERAPY

PN-II-PT-PCCA- New fibre-reinforced composite materials for custom-made Iuliu Hatieganu University of Medicine and 22 Rotaru Horatiu 80.25 2011-3.2-0308 craniofacial implants fabrication Pharmacy Page 2 of 6 Nume Prenume Nr. Cod director de director Titlu proiect Institutie coordonatoare Punctaj Crt depunere proiect de proiect

INTEGRATING SNP PROFILING OF PROSTATE AND PN-II-PT-PCCA- Universitatea de Medicina si Farmacie "Carol 23 Viorel Jinga COLORECTAL CANCER INTO PREDICTIVE MODELS OF 80.00 2011-3.2-1273 Davila" CLINICAL UTILITY Development of magnetic resonance imaging methods to PN-II-PT-PCCA- 24 Andronesi Ovidiu obtain endophenotypes for bio-psychological vulnerability in Universitatea Babes Bolyai 80.00 2011-3.2-1673 mental illnesses - application to major depressive disorder

New therapies using hydrogels with Thuja occidentalis PN-II-PT-PCCA- Universitatea de Medicina si Farmacie 25 Costuleanu Marcel extracts for modulating the induced pluripotent stem cells 79.33 2011-3.2-1768 "Grigore T. Popa" Iasi (iPSC) in dermal wound healing

Interdisciplinary Platform Based on the Intercorelation of PN-II-PT-PCCA- the Neuroadaptative and Integrative Mechanisms in the University of Medicine and Pharmacy Carol 26 Ovidiu-Alexandru Bajenaru 79.25 2011-3.2-1403 Rehabilitation of Loss of Speech and Language Abilities in Davila Neurological Patients National Research and Development PN-II-PT-PCCA- NANOG Pathways- new biomarkers in the diagnosis and 27 Carmen Maria Ardeleanu Institute in the Field of Pathology and 78.33 2011-3.2-1099 personalised therapy monitoring of the esogastric cancer Biomedical Sciences Victor Babes Biowaiving safety and efficacy evaluations for rectal PN-II-PT-PCCA- University of Medicine and Pharmacy Carol 28 Lupuleasa Dumitru semisolid dosage forms based on biorelevant in vitro 78.00 2011-3.2-1197 Davila Bucharest methodology PN-II-PT-PCCA- Protocol for diagnosis and parasitic therapy of inflammatory University of Medicine and Pharmacy Iuliu 29 Dumitrascu Dan Lucian 77.67 2011-3.2-1256 bowel disease based on biopreparation with Trichuris suis. Hatieganu Cluj-Napoca,

PN-II-PT-PCCA- INDOOR EXPOSURE TO MIXTURES AND BRONCHIAL S.C. CENTRUL DE MEDIU SI SANATATE 30 Gurzau Eugen Stelian 77.00 2011-3.2-0226 ASTHMA S.R.L.

PN-II-PT-PCCA- New molecular kit and cryo-media for human amniotic fluid Institute of Cellular Biology and Pathology 31 Maniu Horia 76.67 2011-3.2-1079 alternative stem cell storage "Nicolae Simionescu"

Study of molecular and genetic mechanisms of leukemic PN-II-PT-PCCA- transformation in myelodysplastic and Universitatea de Medicina si Farmacie "Carol 32 Vladareanu Ana-Maria 76.67 2011-3.2-1802 myelodysplastic/myeloproliferative neoplasms - predictive Davila"Bucuresti biomarkers and novel therapeutical strategies

PN-II-PT-PCCA- Magnetic biomimetic scaffolds as alternative strategy for University of Medicine and Pharmacy 33 Verestiuc Liliana 76.50 2011-3.2-1589 bone tissue repair and engineering "Grigore T Popa" Iasi DEVELOPING AND STANDARDIZATION OF MODERN THERAPIES FOR DEGENERATIVE AND NEOPLASIC PN-II-PT-PCCA- Octavian 34 Unc DESEASES BY USING NOVEL BIO-NANO-PHARMACEUTICAL Sc Medical Analysis 75.75 2011-3.2-1420 Dumitru FORMULATIONS BASED ON CHEMICAL AND CELLULAR SUPPORT

Page 3 of 6 Nume Prenume Nr. Cod director de director Titlu proiect Institutie coordonatoare Punctaj Crt depunere proiect de proiect

“RESEARCH IN MOLECULAR EPIDEMIOLOGY AREA TO PN-II-PT-PCCA- National Institute of Infectious Diseases 35 Hristea Adriana IMPROVE INFECTION PREVENTION AND CONTROL OF 75.67 2011-3.2-1565 "Prof. Dr. Matei Bals" MULTI-DRUG-RESISTANT GRAM NEGATIVE BACILLI”

PN-II-PT-PCCA- Carmen Standardization of a new technology for the production of National Institute for Lasers, Plasma and 36 Surdu-Bob 75.50 2011-3.2-1634 CRISTINA engineered implants for skin cancer therapy Radiation Physics

PN-II-PT-PCCA- New PCR-based assays for the rapid detection of resistant 37 Chifiriuc Mariana Carmen University of Bucharest 75.33 2011-3.2-1148 microorganisms in clinical specimens

PN-II-PT-PCCA- A new paradigm of neurocognitive and neuropsychological University of Medicine and Pharmacy "Carol 38 Dulamea Adriana 74.75 2011-3.2-1800 investigation of the man - built environment relationship Davila" GENOTYPIC AND PHENOTYPIC PROFILE OF CANCEROUS PN-II-PT-PCCA- UNIVERSITATEA DE MEDICINA SI FARMACIE 39 GEORGESCU ION CELL IN PROGRESSION AND EVOLUTION OF COLORECTAL 74.67 2011-3.2-1676 DIN CARCINOMA Probabilistic model of embryo-fetal alterations induced by PN-II-PT-PCCA- 40 Vladareanu Radu maternal hematological pathology during pregnancy. Spitalul Universitar de Urgenta Elias 74.67 2011-3.2-1554 Implication of the genetic factor.

PN-II-PT-PCCA- The formulation - biological barrier interplay in optimizing University of Medicine and Pharmacy Carol 41 Miron Dalia 74.33 2011-3.2-0276 drug exposure pattern following topical administration Davila Bucharest

Novel Approach at International Standards of Basic and PN-II-PT-PCCA- Clinical Pharmacology for Autism in Child and the Use of Universitatea de Medicina si Farmacie Carol 42 Coman Oana Andreia 74.33 2011-3.2-1469 Informatics Technology for Enhanced Autism Related Davila Education of Parents and Specialists

PN-II-PT-PCCA- Optimization of autologous bone marrow stem cell therapy Universitatea de Medicina si Farmacie "Carol 43 Dorobantu Maria 73.75 2011-3.2-1036 in patients with ischemic heart failure Davila” Bucuresti

PN-II-PT-PCCA- INNOVATIVE REGENERATIVE THERAPY FOR SPINAL CORD 44 Marin Adela UNIVERSITY OF BUCHAREST 73.67 2011-3.2-1204 INJURIES

Potential applications of novel endoscopic technologies and PN-II-PT-PCCA- 45 Gheorghe Cristian computer aided automatic lesion detection algorithms for Institutul Clinic Fundeni 73.33 2011-3.2-1039 improving screening protocols in colorectal cancer

Prevention of arrhythmic sudden cardiac death by in PN-II-PT-PCCA- 46 VATASESCU RADU GABRIEL athletes by multidisciplinary early detection of arrhythmic WING COMPUTER GROUP SRL 73.33 2011-3.2-1783 substrate and specific electrophysiologic treatment DEVELOPMENT AND EFFICIENCY ASSESSMENT OF SOME PN-II-PT-PCCA- 47 Cimpoiu Claudia BOTANICAL-BASED FORMULAS FOR THE TREATMENT OF Universitatea Babes-Bolyai 73.25 2011-3.2-0213 HUMAN ATOPIC DERMATITIS Page 4 of 6 Nume Prenume Nr. Cod director de director Titlu proiect Institutie coordonatoare Punctaj Crt depunere proiect de proiect

Innovative robotic platform - support of services for PN-II-PT-PCCA- 48 Marinca Vasile assisting and integrating people with locomotor disabilities Universitatea Politehnica Timisoara 73.00 2011-3.2-1014 and/or old people New materials and catheter devices for controlling PN-II-PT-PCCA- 49 Lazar Veronica multispecific biofilms and associated polymicrobial University of Bucharest 72.33 2011-3.2-1051 infections PN-II-PT-PCCA- Development of biochemical and genetic methods for 50 Irina Stoian R&D Irist Labmed 72.25 2011-3.2-1819 diagnosys of mitochondrial diseases

PN-II-PT-PCCA- Cell-regeneration response under phosphatic microspheres University of Agricultural Sciences and 51 Stefan Razvan 71.00 2011-3.2-0971 through IR and Raman spectroscopy Veterinary Medicine Multidisciplinary research related to conditioning work PN-II-PT-PCCA- productivity, the influence of working conditions and skills 52 Radoae Daciana Maria SAM-servicii avansate medicale-srl 69.33 2011-3.2-1507 on the employees' health, for the validation of an complex computerized system.

CLINICAL TRIAL PROTOCOL FOR FURTHER DEVELOPMENT PN-II-PT-PCCA- OF CHEMOTHERAPY DRUGS AIMING TO BLOCK CANCER 53 Dimitriu Dan-Gheorghe Alexandru Ioan Cuza University of Iasi 69.00 2011-3.2-0774 EVOLUTION BY METASTASIS BASED ON EXPERIMENTS, COMPUTER SIMULATIONS AND THEORETICAL STUDIES

PN-II-PT-PCCA- Early detection of liver disorders using non-invasive medical 54 Szilagyi Laszlo Fundatia Sapientia - Universitatea Sapientia 68.33 2011-3.2-1750 imaging Development of novel molecular profiling technologies and PN-II-PT-PCCA- Institute of Cellular Biology and Pathology 55 Manea Adrian therapeutic strategies for personalized medicine in 68.00 2011-3.2-0984 'Nicolae Simionescu' atherosclerosis HIPOIMUNOGENIC IMPLANTABLE BIOMATERIAL FOR PN-II-PT-PCCA- National Institute of Research and 56 Catalin Iordachel TISSUE REGENERATION AND DEVICE FOR CELLULAR 68.00 2011-3.2-0783 Development for Biological Sciences TRANSPLANTATION IN CELLULAR THERAPY Institutului National de Cercetare Dezvoltare PN-II-PT-PCCA- Technology for rapid separation of the stem cells from 57 Radu Mihai pentru Fizica si Inginerie Nucleara „Horia 67.75 2011-3.2-0831 amniotic fluid Hulubei„ Optimization of diagnostic, primary and secondary PN-II-PT-PCCA- prevention schemes in patients with metabolic syndrome. Universitatea de Medicina si Farmacie Iuliu 58 Procopciuc Lucia Maria 67.67 2011-3.2-1461 Computational intelligence modeling for the estimation of Hatieganu cardiovascular risk Bioresorbable implant for preventing complications and PN-II-PT-PCCA- Alexandru Universitatea de Medicina si Farmacie ”Iuliu 59 Georgescu improvement of postoperative tendons repair and 67.33 2011-3.2-0580 Valentin Hatieganu” rehabilitation PN-II-PT-PCCA- University of Medicine and Pharmacy, Targu- 60 Podoleanu Cristian Romanian Injury Surveillance System 65.50 2011-3.2-0249 Mures Page 5 of 6 Nume Prenume Nr. Cod director de director Titlu proiect Institutie coordonatoare Punctaj Crt depunere proiect de proiect

PN-II-PT-PCCA- The Romanian Integrated Non-Communicable Diseases 61 Litan Cristian Marius Babes-Bolyai University Cluj-Napoca 65.00 2011-3.2-0764 Network and Statistical Data Portal Drug resistence mechanisms in classical Hodgkin PN-II-PT-PCCA- CAROL DAVILA UNIVERSITY OF MEDICINE 62 Colita Andrei Lymphoma- NFkB canonical activation pathway 64.50 2011-3.2-1066 AND PHARMACY investigation and new posible therapeutical target MORPHOLOGIC AND GENETIC STUDY OF GASTRIC PN-II-PT-PCCA- 63 ASCHIE MARIANA CARCINOGENESIS FOR SETTING A HISTOMOLECULAR 63.33 2011-3.2-1471 DIAGNOSIS ALGORITHM IN VITRO DISSOLUTION – IN VIVO PHARMACOKINETICS PN-II-PT-PCCA- CORRELATIONS AND DEVELOPEMENT OF BIORELEVANT, 64 mircioiu ion SC ARENA GROUP S.A. 61.50 2011-3.2-1791 PREDICTIVE DISSOLUTION TESTS FOR DRUGS WITH AZOL STRUCTURE

PN-II-PT-PCCA- Wireless embedded sensors for medical prosthesis and Technical University "Gheorghe Asachi"of 65 Burlacu Ramona 60.00 2011-3.2-1643 implants applications Iasi

Research on the creation of a cold plasma device to PN-II-PT-PCCA- 66 Eugen Hnatiuc improve eco toxicological effects of metallic, polymer and University of Apollonia 56.67 2011-3.2-0854 ceramic dental restoration on the human being

PN-II-PT-PCCA- Electronic system for assessment of cardiovascular UNIVERSITATEA DE MEDICINA SI FARMACIE 67 Zagrean Ana-Maria 53.33 2011-3.2-1790 reactivity to thermal stress CAROL DAVILA BUCURESTI

High homocysteine levels caused by genetic and PN-II-PT-PCCA- Pro-Vitam SRL Sfantu Gheorghe, sucursala 68 Fejer Szilard environmental factors in selected population groups: 53.00 2011-3.2-1191 Sfantu Gheorghe incidence and associated molecular mechanisms

ADVANCED INTERVENTIONAL METHOD BASED ON PN-II-PT-PCCA- Clinic Hospital for Oro-Maxillo-Facial Surgery 69 Augustin MIHAI CUSTOMIZED DENTAL IMPLANTS FOR THE IMPLANTO- 53.00 2011-3.2-0043 “Prof.MD. Dan Teodorescu” PROSTHETIC TREATMENT OF EDENTATIONS Study of quality and effect of potential therapeutic factors PN-II-PT-PCCA- from salt mines and developing a national system of Institutul Naţional de Recuperare, Medicina 70 Simionca Iuri Gheorghe 50.00 2011-3.2-1631 speleotherapy centers in purpose of prevention, therapy Fizica si Balneoclimatologie and medical rehabilitation Development and Implementation of a Program of PN-II-PT-PCCA- 71 georgeta burlea Diagnosis, Prevention and Correction of Postural Deficits in Universitatea Apollonia din Iaşi 38.25 2011-3.2-0915 Children and Young Adults Experimental and technology research to perform a PN-II-PT-PCCA- 72 Carol Stanciu preparation with preventive and curative effects to Apollonia University from Iasi 33.75 2011-3.2-0824 eradicate Helicobacter pylori infection

Page 6 of 6