Mai Muuttunut Pilit Muut Aidi Mini
MAIMUUTTUNUT US009963689B2 PILIT MUUT AIDI MINI (12 ) United States Patent ( 10 ) Patent No. : US 9 ,963 , 689 B2 Doudna et al. ( 45) Date of Patent: May 8 , 2018 ( 54 ) CASI CRYSTALS AND METHODS OF USE FOREIGN PATENT DOCUMENTS THEREOF WO WO 2013 / 126794 AL 8 / 2013 ( 71 ) Applicant: The Regents of the University of wo WO 2013 / 142578 A19 / 2013 California , Oakland , CA (US ) WO WO 2013 / 176772 A1 11/ 2013 ( 72 ) Inventors : Jennifer A . Doudna , Oakland , CA OTHER PUBLICATIONS (US ) ; Samuel H . Sternberg , Oakland , McPherson , A . Current Approaches to Macromolecular Crystalli CA (US ) ; Martin Jinek , Oakland , CA zation . European Journal of Biochemistry . 1990 . vol . 189 , pp . (US ) ; Fuguo Jiang , Oakland , CA (US ); 1 - 23 . * Emine Kaya , Oakland , CA (US ) ; Kundrot, C . E . Which Strategy for a Protein Crystallization Project ? Cellular Molecular Life Science . 2004 . vol . 61, pp . 525 - 536 . * David W . Taylor, Jr. , Oakland , CA Benevenuti et al. , Crystallization of Soluble Proteins in Vapor (US ) Diffusion for X - ray Crystallography , Nature Protocols , published on - line Jun . 28 , 2007 , 2 ( 7 ) : 1633 - 1651. * ( 73 ) Assignee : THE REGENTS OF THE Cudney R . Protein Crystallization and Dumb Luck . The Rigaku UNIVERSITY OF CALIFORNIA , Journal. 1999 . vol. 16 , No . 1 , pp . 1 - 7 . * Drenth , “ Principles of Protein X - Ray Crystallography ” , 2nd Edi Oakland , CA (US ) tion , 1999 Springer - Verlag New York Inc ., Chapter 1 , p . 1 - 21. * Moon et al . , “ A synergistic approach to protein crystallization : ( * ) Notice : Subject to any disclaimer , the term of this Combination of a fixed -arm carrier with surface entropy reduction ” , patent is extended or adjusted under 35 Protein Science , 2010 , 19 : 901 -913 .
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