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Update on Emergency Department Visits Involving Energy Drinks: a Continuing Public Health Concern January 10, 2013

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Update on Emergency Department Visits Involving Energy Drinks: a Continuing Public Health Concern January 10, 2013 January 10, 2013 Update on Emergency Department Visits Involving Energy Drinks: A Continuing Public Health Concern Energy drinks are flavored beverages containing high amounts of caffeine and typically other additives, such as vitamins, taurine, IN BRIEF herbal supplements, creatine, sugars, and guarana, a plant product containing concentrated caffeine. These drinks are sold in cans and X The number of emergency bottles and are readily available in grocery stores, vending machines, department (ED) visits convenience stores, and bars and other venues where alcohol is sold. involving energy drinks These beverages provide high doses of caffeine that stimulate the doubled from 10,068 visits in central nervous system and cardiovascular system. The total amount 2007 to 20,783 visits in 2011 of caffeine in a can or bottle of an energy drink varies from about 80 X Among energy drink-related to more than 500 milligrams (mg), compared with about 100 mg in a 1 ED visits, there were more 5-ounce cup of coffee or 50 mg in a 12-ounce cola. Research suggests male patients than female that certain additives may compound the stimulant effects of caffeine. patients; visits doubled from Some types of energy drinks may also contain alcohol, producing 2007 to 2011 for both male a hazardous combination; however, this report focuses only on the and female patients dangerous effects of energy drinks that do not have alcohol. X In each year from 2007 to Although consumed by a range of age groups, energy drinks were 2011, there were more patients originally marketed to appeal to youths and were reported to aged 18 to 39 than patients have been consumed by 30 to 50 percent of children, adolescents, in other age groups involved and young adults.2 Marketing suggests benefits such as increased in energy drink-related visits; energy and stamina, weight loss, and enhanced physical and mental however, the largest increase performance.2 More concentrated forms of energy drinks, known as was seen among patients energy shots, have become increasingly popular among a wider range aged 40 or older, for whom of age groups, including older adults.3 Marketing analysts reported visits increased 279 percent increasing sales of energy shots in 2011 that were expected to continue from 1,382 visits in 2007 to through 2012.3 The concentrated amount of caffeine and other 5,233 visits in 2011 ingredients in these drinks has come under scrutiny as the Food and X In 2011, more than half of Drug Administration disclosed reports of adverse events with mention energy drink-related ED visits 4 of the popular energy shot 5-Hour Energy. involved energy drinks only (58 Consumption of energy drinks is a rising public health problem percent), and the remaining 42 because medical and behavioral consequences can result from excessive percent involved other drugs caffeine intake. A growing body of scientific evidence documents harmful health effects of energy drinks, particularly for children, DAWN_126 THE DAWN REPORT: Update on Emergency Department Visits Involving Energy Drinks: A Continuing Public Health Concern January 10, 2013 adolescents, and young adults.2 Research has established visits beginning in 2005; however, statistical tests were that, among college students, there are associations not used until 2007, when the number of ED visits between energy drink consumption and problematic exceeded 10,000. The number of ED visits involving behaviors such as marijuana use, sexual risk taking, energy drinks doubled from 10,068 visits in 2007 to fighting, smoking, drinking, and prescription drug 20,783 visits in 2011. From 2007 to 2011, increases did misuse.5,6 In one study, bar patrons who consumed not always occur annually, but an overall upward trend alcohol mixed with energy drinks were 3 times more was evident. likely to leave a bar highly intoxicated and were 4 times The majority of energy drink-related ED visits involved more likely to intend to drive while intoxicated than either adverse reactions8 or misuse or abuse of drugs9; those who did not consume alcohol mixed with energy 6 other reasons are not presented because they represent drinks. This latter finding may be because the high less than 5 percent of visits. In each year from 2007 to levels of caffeine found in energy drinks can mask 2011, visits involving adverse reactions were about twice the symptoms associated with being intoxicated (e.g., as commonly reported as visits involving misuse or abuse. feeling lethargic). Individuals, especially young drinkers, Energy drink-related ED visits involving adverse reactions may incorrectly believe that consumption of caffeine doubled from 6,996 visits in 2007 to 14,042 visits in can “undo” the effects of alcohol intake and make it 2011 (Figure 2). The most noticeable increases occurred safe to drive after drinking. Because of the popularity of in 2008 (54 percent increase from 2007) and 2011 energy drinks and the burgeoning literature suggesting (101 percent increase from 2007). Energy drink-related the risks involved with their use, gaining additional ED visits involving misuse or abuse of drugs nearly information about these beverages is important. doubled from 3,060 visits in 2007 to 6,090 visits in 2011. The Drug Abuse Warning Network (DAWN) is a public health surveillance system that monitors drug-related emergency department (ED) visits in the United States Figure 1. Energy Drink-Related Emergency and can be used as a source of information for assessing Department (ED) Visits, by Year: 2005 to 2011 the more negative medical consequences associated with consuming energy drinks. To be a DAWN case, the ED 25,000 visit must involve a drug, either as the direct cause of the 20,783 visit or as a contributing factor. Such a visit is referred 20,000 to as a “drug-related visit.” Drugs include alcohol; 16,059 illegal drugs, such as cocaine, heroin, and marijuana; 15,219 pharmaceuticals (e.g., over-the-counter medicines and 15,000 prescription medications); and nutraceuticals, such 13,119 as nutritional supplements, vitamins, and caffeine 10,068 products. A previous report addressing ED visits 10,000 involving energy drinks was published using 2009 data7; Number of ED Visits this issue of The DAWN Report highlights trend data 5,000 3,210 for energy drinks from 2007 to 2011, as well as drug 1,494 combinations found in 2011. 0 Trends in ED Visits 20052006 2007 2008* 2009 2010* 2011* In years prior to 2007, ED visits involving energy drinks * Compared with the number of visits in 2007, the difference was statistically were either not shown due to low statistical precision significant at the .05 level. The number of visits in years prior to 2007 were not used in statistical tests because of low numbers; the number of visits (in 2004) or because they occurred in very low numbers in 2004 was not shown because of low statistical precision. (in 2005 and 2006). Figure 1 shows the trend in ED Source: 2011 SAMHSA Drug Abuse Warning Network (DAWN). 2 THE DAWN REPORT: Update on Emergency Department Visits Involving Energy Drinks: A Continuing Public Health Concern January 10, 2013 Trends in ED Visits by Demographic Groups patients aged 40 or older, ED visits involving energy Among energy drink-related ED visits, there were drinks increased 279 percent from 1,382 visits in 2007 more male patients than female patients in each year to 5,233 visits in 2011 (Figure 4). Visits for younger since 2007, accounting for approximately two thirds adults (aged 18 to 25 and aged 26 to 39) appeared to or more of visits. An exception occurred in 2008, have increased, but the difference was not statistically when half (54 percent) of visits involving energy significant between 2007 and 2011. Visits among drinks were made by male patients (data not shown). adolescents aged 12 to 17 remained stable. ED visits involving energy drinks doubled from 2007 Drug Combinations with Energy Drinks to 2011 for both male and female patients (Figure 3). More specifically, visits by males increased from 7,210 Of the 20,783 ED visits involving energy drinks in visits in 2007 to 14,905 visits in 2011, and visits by 2011, more than half involved energy drinks only females increased from 2,854 visits in 2007 to 5,878 (58 percent), and the remaining 42 percent involved visits in 2011. other drugs (Table 1). Pharmaceuticals were most commonly combined with energy drinks (27 percent), In each year from 2007 to 2011, patients aged 18 to 25 with 9 percent involving energy drinks and central were most commonly involved in energy drink-related nervous system stimulants (e.g., Adderall®, Ritalin®). ED visits, followed by patients aged 26 to 39. An About 13 percent of visits involved energy drinks and exception occurred in 2010, when patients aged 26 to alcohol and one tenth of visits (10 percent) involved 39 were most commonly involved in energy drink- energy drinks and illicit drugs, with 5 percent involving related ED visits (44 percent), followed by patients energy drinks and marijuana. aged 18 to 25 (29 percent) (data not shown). Among Figure 2. Reason for Energy Drink-Related Emergency Figure 3. Energy Drink-Related Emergency Department (ED) Visits, by Year: 2005 to 2011 Department (ED) Visits, by Gender: 2007 and 2011 15,000 Adverse Reactions 14,042* 16,000 14,905 2007 Misuse or Abuse 2011 14,000 12,000 10,770* 12,000 9,618 9,000 10,000 6,996 8,798 8,000 7,210 6,000 5,878 6,090* 6,000 Number of ED Visits Number of ED Visits 5,284* 5,368* 4,312 4,000 2,854 3,000 1,973 3,060 840 2,000 1,704 583 0 0 20052006 2007 2008 2009 20112010 Male* Female* * Compared with the number of visits in 2007, the difference was statistically * The difference between the number of visits in 2007 and 2011 was significant at the .05 level.
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