ii Contents of Volume 81, 2017
CONTENTS OF VOLUME 81, 2017
Message From the Editor-in-Chief
1. Circulation Journal Has Changed Its Style Toyoaki Murohara ········· 1 2. Editorial Statistics and Best Reviewers Award for 2016 Toyoaki Murohara ········· 127 3. Circulation Journal Awards for the Year 2016 Toyoaki Murohara ········· 273 4. Rapid Publication and Announcement of the 2017 JCS Meeting Activities Toyoaki Murohara ········· 615 5. Announcement of the 2017 JCS Meeting Activities (2) Toyoaki Murohara ········· 767 6. Message From the Editor-in-Chief Toyoaki Murohara ········· 1063 7. Message From the Editor-in-Chief Toyoaki Murohara ········· 1241 8. Message From the Editor-in-Chief Toyoaki Murohara ········· 1377
In Memoriam
1. Mitsuhiro Yokoyama, MD, PhD 1943–2016 Ken-ichi Hirata ········· 901
Reviews
1. Coronary Microvascular Dysfunction ― Epidemiology, Pathogenesis, Prognosis, Diagnosis, Risk Factors and Therapy ― Cheng Chen, Janet Wei, Ahmed AlBadri, Parham Zarrini, C. Noel Bairey Merz ········· 3 2. Modeling Inherited Arrhythmia Disorders Using Induced Pluripotent Stem Cell-Derived Cardiomyocytes Vassilios J. Bezzerides, Donghui Zhang, William T. Pu ········· 12 3. Reperfusion Damage ― A Story of Success, Failure, and Hope ― Roberto Ferrari, Cristina Balla, Michele Malagù, Gabriele Guardigli, Giampaolo Morciano, Matteo Bertini, Simone Biscaglia, Gianluca Campo ········· 131 4. Myocardial Regeneration for Humans ― Modifying Biology and Manipulating Evolution ― Kathleen M. Broughton, Mark A. Sussman ········· 142 5. Pathophysiology of Intermittent Claudication in Peripheral Artery Disease Naomi M. Hamburg, Mark A. Creager ········· 281 6. The Brugada Syndrome ― From Gene to Therapy ― Antonio Curcio, Giuseppe Santarpia, Ciro Indolfi ········· 290 7. Significance and Value of Endomyocardial Biopsy Based on Our Own Experience Hatsue Ishibashi-Ueda, Taka-aki Matsuyama, Keiko Ohta-Ogo, Yoshihiko Ikeda ········· 417 8. Critical Care Management Focused on Optimizing Brain Function After Cardiac Arrest Ryuta Nakashima, Toru Hifumi, Kenya Kawakita, Tomoya Okazaki, Satoshi Egawa, Akihiko Inoue, Ryutaro Seo, Nobuhiro Inagaki, Yasuhiro Kuroda ········· 427 9. Heart Transplantation in Asia Hae-Young Lee, Byung-Hee Oh ········· 617 10. Sterile Inflammation and Degradation Systems in Heart Failure Kazuhiko Nishida, Kinya Otsu ········· 622 11. The Complex Genetic Basis of Congenital Heart Defects Ehiole Akhirome, Nephi A. Walton, Julie M. Nogee, Patrick Y. Jay ········· 629 12. Dipeptidyl Peptidase-IV Inhibition for the Treatment of Cardiovascular Disease ― Recent Insights Focusing on Angiogenesis and Neovascularization ― Yanna Lei, Lina Hu, Guang Yang, Limei Piao, Minggen Jin, Xianwu Cheng ········· 770 13. Sleep-Disordered Breathing in Heart Failure ― A Therapeutic Dilemma ― Nobuhiko Haruki, John S. Floras ········· 903
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14. Atrial Natriuretic Peptide ― Old But New Therapeutic in Cardiovascular Diseases ― Tomoko Ichiki, John C. Burnett Jr ········· 913 15. Role of Adipokines in Cardiovascular Disease Wayne Bond Lau, Koji Ohashi, Yajing Wang, Hayato Ogawa, Toyoaki Murohara, Xin-Liang Ma, Noriyuki Ouchi ········· 920 16. Recent Progress Using Pluripotent Stem Cells for Cardiac Regenerative Therapy Hajime Ichimura, Yuji Shiba ········· 929 17. Bioresorbable Vascular Scaffolds ― Are We Facing a Time of Crisis or One of Breakthrough? ― Jeehoon Kang, Jung-Kyu Han, Han-Mo Yang, Kyung Woo Park, Hyun-Jae Kang, Bon-Kwon Koo, Hyo-Soo Kim ········· 1065 18. Prognostic Value of Chronic Kidney Disease Measures in Patients With Cardiac Disease Yejin Mok, Shoshana H. Ballew, Kunihiro Matsushita ········· 1075 19. Noninvasive Fractional Flow Reserve Derived From Coronary Computed Tomography Angiography ― Is This Just Another New Diagnostic Test or the Long-Awaited Game Changer? ― Hiromasa Otake, Charles A. Taylor, Hitoshi Matsuo, Nobuhiro Tanaka, Takashi Akasaka ········· 1085 20. Investigations of Carotid Stenosis to Identify Vulnerable Atherosclerotic Plaque and Determine Individual Stroke Risk Madieke I. Liem, Fiona Kennedy, Leo H. Bonati, Aad van der Lugt, Bram F. Coolen, Aart J. Nederveen, Hans R. Jager, Martin M. Brown, Paul J. Nederkoorn ········· 1246 21. Clinical Implications of Electrocardiograms for Patients With Type A Acute Aortic Dissection Masami Kosuge, Kazuo Kimura, Keiji Uchida, Munetaka Masuda, Kouichi Tamura ········· 1254 22. ANGPTL2 ― A New Causal Player in Accelerating Heart Disease Development in the Aging ― Yuichi Oike, Zhe Tian, Keishi Miyata, Jun Morinaga, Motoyoshi Endo, Tsuyoshi Kadomatsu ········· 1379 23. Development of Novel Therapies for Cardiovascular Diseases by Clinical Application of Basic Research Kimio Satoh ········· 1557 24. Prothrombin Complex Concentrate for Vitamin K Antagonist-Associated Intracranial Hemorrhage ― Global Evidence and the Japanese Perspective ― Masahiro Yasaka, Andres Brainsky, Kazunori Toyoda ········· 1564 25. Metabolic Considerations in Atrial Fibrillation ― Mechanistic Insights and Therapeutic Opportunities ― Masahide Harada, Jonathan Melka, Yoshihiro Sobue, Stanley Nattel ········· 1749
Report of Heart Transplantation in Japan
1. Registry Report on Heart Transplantation in Japan (June 2016) Norihide Fukushima, Minoru Ono, Yoshikatsu Saiki, Yoshiki Sawa, Shinichi Nunoda, Mitsuaki Isobe ········· 298
Congress Reports
2016 AHA Report 1. Report of the American Heart Association (AHA) Scientific Sessions 2016, New Orleans Makoto Amaki, Nao Konagai, Masashi Fujino, Shouji Kawakami, Kazuhiro Nakao, Takuya Hasegawa, Yasuo Sugano, Yoshio Tahara, Satoshi Yasuda ········· 22 2017 ACC Report 2. Report of the Annual Scientific Sessions of the American College of Cardiology (ACC), Washington DC Takafumi Hiro ········· 777 2017 JCS Report 3. Overview of the 81st Annual Scientific Meeting of the Japanese Circulation Society ― Cardiovascular Medicine for the Next Generation ― Noboru Fujino, Tsuyoshi Yoshimuta, Fukiko Ichida, Koichiro Kinugawa, Kazuo Usuda, Michihiko Kitayama, Hidekazu Ino, Masa-aki Kawashiri, Hiroshi Tada, Sumio Mizuno, Kenshi Hayashi, Hirofumi Takemura, Masakazu Yamagishi on behalf of all the members of the Japanese Circulation Society in Hokuriku District ········· 1261 2017 ESC Report 4. European Society of Cardiology (ESC) Annual Congress Report From Barcelona 2017 Kimio Satoh, Jun Takahashi, Yasuharu Matsumoto, Shunsuke Tatebe, Tatsuo Aoki, Yoku Kikuchi, Kiyotaka Hao, Kazuma Ohyama, Masamichi Nogi, Akira Suda, Shintaro Kasahara, Koichi Sato, Sadamitsu Ichijo, Hiroaki Shimokawa ········· 1758
Editorials
1. Hospitalization Deteriorates Performance of Activities of Daily Living by Super-Elderly Patients With Heart Failure Hideo Izawa, Yuji Kohno, Wakaya Fujiwara, Mutsuharu Hayashi ········· 28
Circulation Journal Vol.81, December 2017 iv Contents of Volume 81, 2017
2. Genitourinary Hemorrhagic Complications and Malignancies in Patients Receiving Anticoagulation Therapy Eitaro Kodani ········· 149 3. Timing of Anticoagulant Therapy After Acute Ischemic Stroke Ryu Matsuo, Masahiro Kamouchi ········· 151 4. More Attention Should Be Paid to Abnormalities of Circadian Blood Pressure Rhythm in Heart Failure Patients Mamiko Kai, Hisashi Kai ········· 153 5. Asian Perspective of the EMPA-REG OUTCOME Study Yasuko K. Bando, Toyoaki Murohara ········· 155 6. Assessment of Atherosclerosis ― Vascular Imaging Tests and Vascular Function Tests ― Yukihito Higashi ········· 304 7. Optimal Anticoagulation for Patients With Atrial Fibrillation — Benefits for Reducing Stroke Severity — Masahiro Kamouchi ········· 306 8. Antithrombotic Regimens in Patients Undergoing Transcatheter Aortic Valve Implantation Noriaki Tabata, Kenichi Tsujita ········· 308 9. Rigid Left Ventricle With Attenuated Torsion as the Integrally Deteriorated Form of Dilated Cardiomyopathy Yoshihiro Seo, Tomoko Ishizu, Kazutaka Aonuma ········· 440 10. Improvement in Quality of Life in Chronic Thromboembolic Pulmonary Hypertension With Balloon Pulmonary Angioplasty Toru Satoh ········· 442 11. Renin-Angiotensin-Aldosterone System and Natriuretic Peptides as Possible Targets of Waon Therapy in Heart Failure Arata Fukushima, Shintaro Kinugawa ········· 635 12. Outstanding Effect of Physical Exercise on Endothelial Function Even in Children and Adolescents Kensuke Noma, Yasuki Kihara, Yukihito Higashi ········· 637 13. How Should We Treat School-Aged Children With Borderline QT Prolongation? Seiko Ohno ········· 640 14. Tolvaptan, Is It a Trump to Worsening Renal Function? Shin-ichi Momomura ········· 642 15. Gamma-Glutamyl Transferase as a Risk Biomarker of Cardiovascular Disease ― Does It Have Another Face? ― Yoshihiro Seo, Kazutaka Aonuma ········· 783 16. Getting Osteoporotic Fracture Risk Into Vascular Structure and Function ― Do You Know Your FRAX® Score? ― Toshihiro Tsuruda, Kazuo Kitamura ········· 786 17. Translational Study of Hydrogen Gas Inhalation as Adjuncts to Reperfusion Therapy for Acute Myocardial Infarction Hiroshi Asanuma, Masafumi Kitakaze ········· 936 18. Novel Strategies for the Management of Nocturnal Hypertension Masaaki Miyata, Mitsuru Ohishi ········· 938 19. QRS Score ― Possibilities and Limitations ― Jun Kishihara, Junya Ako ········· 1094 20. Association Between Bathing and Sudden Death Yoshio Tahara ········· 1096 21. Do We Expect Any Pleiotropic Effect of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibition for Reducing Cardiovascular Events Beyond Low-Density Lipoprotein Cholesterol Reduction? Hayato Tada, Masa-aki Kawashiri, Masakazu Yamagishi ········· 1098 22. Yummy Food Is Made From Fat and Sugar Shichiro Abe, Setsu Nishino, Tomoaki Kanaya, Teruo Inoue ········· 1100 23. Hypoalbuminemia and Inflammation as Prognostic Markers in Patients Undergoing Percutaneous Coronary Intervention Koichi Kaikita, Kenichi Tsujita ········· 1268 24. Fractional Flow Reserve in Japanese Routine Clinical Practice Hitoshi Matsuo, Junko Honye ········· 1270 25. Lipid-Lowering Therapy With Monoclonal Antibodies to Proprotein Convertase Subtilisin-Kexin Type 9 ― Lessons From Recent Clinical Trials ― Hideki Ishii, Toyoaki Murohara ········· 1386 26. Genesis and the Risk Score of Atrial Fibrillation for Personalized Management Akihiko Shimizu ········· 1574 27. Miniaturized Leadless Cardiac Pacemakers ― Can They Overcome the Problems With Transvenous Pacing Systems? ― Yasushi Oginosawa, Ritsuko Kohno, Hisaharu Ohe, Haruhiko Abe ········· 1576 28. What Should Be Generalized Diagnostic Markers for Peripartum Cardiomyopathy? Ichiro Sakuma, Toshihisa Anzai ········· 1578
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29. Cardiac Sodium Channel Disease Modeling Using Patient-Derived Induced Pluripotent Stem Cells Shin Kadota, Naoko Shiba, Yuji Shiba ········· 1764 30. Prediction Models ― Why Are They Used or Not Used? ― Fumiaki Nakamura, Michikazu Nakai ········· 1766 31. Should We Include a Defibrillator for All Cardiac Resynchronization Therapy? ― Comparison of Cardiac Resynchronization Therapy Without and With Defibrillation ― Masato Fukunaga, Kenji Ando ········· 1768 32. Chronic Obstructive Pulmonary Disease and Atherosclerosis ― Warning From the Hisayama Study ― Takafumi Okura ········· 1770 33. Mitochondrial Dysfunction and Left Ventricular Structural Remodeling After Acute Myocardial Infarction ― Usefulness of Leukocyte Mitochondrial Copy Number ― Ryuji Tsuburaya ········· 1772
Late Breaking Clinical Trial (JCS 2017)
1. The Effects of Hydrogen Gas Inhalation on Adverse Left Ventricular Remodeling After Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction ― First Pilot Study in Humans ― Yoshinori Katsumata, Fumiya Sano, Takayuki Abe, Tomoyoshi Tamura, Taishi Fujisawa, Yasuyuki Shiraishi, Shun Kohsaka, Ikuko Ueda, Koichiro Homma, Masaru Suzuki, Shigeo Okuda, Yuichiro Maekawa, Eiji Kobayashi, Shingo Hori, Junichi Sasaki, Keiichi Fukuda, Motoaki Sano ········· 940 2. Comparative Effects of an Angiotensin II Receptor Blocker (ARB)/Diuretic vs. ARB/Calcium-Channel Blocker Combination on Uncontrolled Nocturnal Hypertension Evaluated by Information and Communication Technology- Based Nocturnal Home Blood Pressure Monitoring ― The NOCTURNE Study ― Kazuomi Kario, Naoko Tomitani, Hiroshi Kanegae, Hajime Ishii, Kazuaki Uchiyama, Kayo Yamagiwa, Toshihiko Shiraiwa, Tomohiro Katsuya, Tetsuro Yoshida, Kiyomi Kanda, Shinji Hasegawa, Satoshi Hoshide ········· 948 3. Five-Year Outcomes of the First Pivotal Clinical Trial of Balloon-Expandable Transcatheter Aortic Valve Replacement in Japan (PREVAIL JAPAN) Yoshiki Sawa, Morimasa Takayama, Tsuyoshi Goto, Shuichiro Takanashi, Tatsuhiko Komiya, Tetsuya Tobaru, Koichi Maeda, Toru Kuratani, Yasushi Sakata on behalf of the PREVAIL JAPAN Investigators ········· 1102 4. Midterm Outcomes With a Self-Expandable Transcatheter Heart Valve in Japanese Patients With Symptomatic Severe Aortic Stenosis Yoshiki Sawa, Kei Torikai, Junjiro Kobayashi, Hiroshi Niinami, Toru Kuratani, Koichi Maeda, Hideaki Kanzaki, Nobuyuki Komiyama, Yutaka Tanaka, Angie Zhang, Shigeru Saito ········· 1108 5. AVJ-514 Trial ― Baseline Characteristics and 30-Day Outcomes Following MitraClip® Treatment in a Japanese Cohort ― Kentaro Hayashida, Satoshi Yasuda, Takashi Matsumoto, Makoto Amaki, Shingo Mizuno, Tetsuya Tobaru, Kentaro Jujo, Tatsushi Ootomo, Junichi Yamaguchi, Keiichi Fukuda, Shigeru Saito, Elyse Foster, Atif Qasim, Masafumi Kitakaze, Ryohei Yozu, Morimasa Takayama ········· 1116
Late Breaking Cohort Study (JCS 2017)
1. Long-Term Outcomes of Non-ST-Elevation Myocardial Infarction Without Creatine Kinase Elevation ― The J-MINUET Study ― Masaharu Ishihara, Koichi Nakao, Yukio Ozaki, Kazuo Kimura, Junya Ako, Teruo Noguchi, Masashi Fujino, Satoshi Yasuda, Satoru Suwa, Kazuteru Fujimoto, Yasuharu Nakama, Takashi Morita, Wataru Shimizu, Yoshihiko Saito, Atsushi Hirohata, Yasuhiro Morita, Teruo Inoue, Atsunori Okamura, Masaaki Uematsu, Kazuhito Hirata, Kengo Tanabe, Yoshisato Shibata, Mafumi Owa, Kenichi Tsujita, Hiroshi Funayama, Nobuaki Kokubu, Ken Kozuma, Tetsuya Tobaru, Shigeru Oshima, Michikazu Nakai, Kunihiro Nishimura, Yoshihiro Miyamoto, Hisao Ogawa on behalf of J-MINUET Investigators ········· 958
Original Articles
Aortic Disease (6) 1. Evaluation and Influence of Brachiocephalic Branch Re-entry in Patients With Type A Acute Aortic Dissection Shota Yasuda, Kiyotaka Imoto, Keiji Uchida, Norihisa Karube, Tomoyuki Minami, Motohiko Goda, Shinichi Suzuki, Munetaka Masuda ········· 30 2. High Pulse Wave Velocity Has a Strong Impact on Early Carotid Atherosclerosis in a Japanese General Male Population Takuro Kubozono, Masaaki Miyata, Shin Kawasoe, Satoko Ojima, Shiro Yoshifuku, Hironori Miyahara, Shigeho Maenohara, Mitsuru Ohishi ········· 310 3. Nutrition Status Predicts Severity of Vascular Calcification in Non-Dialyzed Chronic Kidney Disease Kazuhiro Harada, Susumu Suzuki, Hideki Ishii, Kenshi Hirayama, Toshijiro Aoki, Yohei Shibata, Yosuke Negishi, Takuya Sumi, Kazuhiro Kawashima, Ayako Kunimura, Yosuke Tatami, Toshiki Kawamiya, Dai Yamamoto, Ryota Morimoto, Yoshinari Yasuda, Toyoaki Murohara ········· 316
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4. Exercise Transcutaneous Oximetry of the Buttocks ― External Validation With Computed Tomography Angiography ― Martin Audonnet, Isabelle Signolet, Christophe Colas-Ribas, Myriam Ammi, Pierre Abraham, Samir Henni ········· 1123 5. Anatomic Feasibility of Next-Generation Stent Grafts for the Management of Type A Aortic Dissection in Japanese Patients Naoki Fujimura, Shinji Kawaguchi, Hideaki Obara, Akihiro Yoshitake, Masanori Inoue, Satoshi Otsubo, Yuko Kitagawa, Hideyuki Shimizu ········· 1388 6. Oral Steroid Use and Abdominal Aortic Aneurysm Expansion ― Positive Association ― Yuta Tajima, Hitoshi Goto, Masato Ohara, Munetaka Hashimoto, Daijiro Akamatsu, Takuya Shimizu, Noriyuki Miyama, Ken Tsuchida, Keiichiro Kawamura, Michihisa Umetsu, Shunya Suzuki, Noriaki Ohuchi ········· 1774 Arrhythmia/Electrophysiology (29) 7. Clinical Significance of Hematuria in Atrial Fibrillation With Oral Anticoagulation Therapy Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung ········· 158 8. Long-Term Efficacy of Implantable Cardioverter Defibrillator in Repaired Tetralogy of Fallot ― Role of Anti- tachycardia Pacing ― Ryuta Henmi, Koichiro Ejima, Daigo Yagishita, Yuji Iwanami, Tomomi Nishimura, Daiji Takeuchi, Keiko Toyohara, Morio Shoda, Nobuhisa Hagiwara ········· 165 9. What Is the Acute Antral Lesion Size After Pulmonary Vein Isolation Using Different Balloon Ablation Technologies? Laura Perrotta, Athanasios Konstantinou, Stefano Bordignon, Alexander Fuernkranz, Daniela Dugo, KR Julian Chun, Boris Schmidt ········· 172 10. Timing of Treatment Initiation With Oral Anticoagulants for Acute Ischemic Stroke in Patients With Nonvalvular Atrial Fibrillation Ichiro Deguchi, Norio Tanahashi, Masaki Takao ········· 180 11. Prognostic Impact of Atrial Fibrillation and New Risk Score of Its Onset in Patients at High Risk of Heart Failure ― A Report From the CHART-2 Study ― Takeshi Yamauchi, Yasuhiko Sakata, Masanobu Miura, Takeo Onose, Kanako Tsuji, Ruri Abe, Takuya Oikawa, Shintaro Kasahara, Masayuki Sato, Kotaro Nochioka, Takashi Shiroto, Jun Takahashi, Satoshi Miyata, Hiroaki Shimokawa on behalf of the CHART-2 Investigators ········· 185 12. Life-Threatening Ventricular Arrhythmia and Brugada-Type ST-Segment Elevation Associated With Acute Ischemia of the Right Ventricular Outflow Tract Rena Nakamura, Mitsuhiro Nishizaki, Kiko Lee, Masato Shimizu, Hiroyuki Fujii, Noriyoshi Yamawake, Harumizu Sakurada, Masayasu Hiraoka, Mitsuaki Isobe ········· 322 13. Improvement in the Quality of Life and Exercise Performance in Relation to the Plasma B-Type Natriuretic Peptide Level After Catheter Ablation in Patients With Asymptomatic Persistent Atrial Fibrillation Atsuhiko Yagishita, Yasuteru Yamauchi, Hironori Sato, Shu Yamashita, Tatsuhiko Hirao, Takamichi Miyamoto, Kenzo Hirao, Mitsuaki Isobe ········· 444 14. Left Atrial Appendage Thrombi Formation in Japanese Non-Valvular Atrial Fibrillation Patients During Anticoagulation Therapy ― Warfarin vs. Direct Oral Anticoagulants ― Mihoko Kawabata, Masahiko Goya, Takeshi Sasaki, Shingo Maeda, Yasuhiro Shirai, Takuro Nishimura, Takakatsu Yoshitake, Shinya Shiohira, Mitsuaki Isobe, Kenzo Hirao ········· 645 15. Age-Specific Differences in the Duration of Prehospital Cardiopulmonary Resuscitation Administered by Emergency Medical Service Providers Necessary to Achieve Favorable Neurological Outcome After Out-of-Hospital Cardiac Arrest Akira Funada, Yoshikazu Goto, Hayato Tada, Ryota Teramoto, Masaya Shimojima, Kenshi Hayashi, Masakazu Yamagishi ········· 652 16. Early and Late Atrial Arrhythmias After Lung Transplantation ― Incidence, Predictive Factors and Impact on Mortality ― Laurence Jesel, Jérémie Barraud, Han S. Lim, Halim Marzak, Nathan Messas, Sandrine Hirschi, Nicola Santelmo, Anne Olland, Pierre Emmanuel Falcoz, Gilbert Massard, Michel Kindo, Patrick Ohlmann, Michel Chauvin, Olivier Morel, Romain Kessler ········· 660 17. Particular Morphology of Inferior Pulmonary Veins and Difficulty of Cryoballoon Ablation in Patients With Paroxysmal Atrial Fibrillation Ryobun Yasuoka, Takashi Kurita, Yasuhito Kotake, Naotaka Hashiguchi, Koichiro Motoki, Kazuhiro Kobuke, Yoshitaka Iwanaga, Shunichi Miyazaki ········· 668 18. Novel Scoring System for Distinction Between Paroxysmal and Non-Paroxysmal Atrial Fibrillation Jun Oikawa, Shinichi Niwano, Hidehira Fukaya, Hironori Nakamura, Tazuru Igarashi, Tamami Fujiishi, Naruya Ishizue, Tomoharu Yoshizawa, Akira Satoh, Jun Kishihara, Masami Murakami, Junya Ako ········· 788 19. Characteristics and Prognosis of Pacemaker-Identified New-Onset Atrial Fibrillation in Japanese People Yutaka Ogino, Toshiyuki Ishikawa, Tomoaki Ishigami, Katsumi Matsumoto, Junya Hosoda, Kouhei Iguchi, Hirooki Matsushita, Yuka Taguchi, Yoriko Horiguchi, Kazuo Kimura ········· 794 20. Effect of Obesity on the Prognostic Impact of Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction Mayuko Yagawa, Yuji Nagatomo, Yuki Izumi, Keitaro Mahara, Hitonobu Tomoike, Yasuyuki Shiraishi, Takashi Kohno, Atsushi Mizuno, Ayumi Goda, Shun Kohsaka, Tsutomu Yoshikawa for the West Tokyo Heart Failure (WET-HF) Registry Collaborative Group ········· 966
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21. Three-Year Clinical Outcome After 2nd-Generation Cryoballoon-Based Pulmonary Vein Isolation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation ― A 2-Center Experience ― Christian-H. Heeger, Erik Wissner, Milena Knöll, Benedikt Knoop, Bruno Reissmann, Shibu Mathew, Christian Sohns, Christine Lemes, Tilman Maurer, Francesco Santoro, Johannes Riedl, Osamu Inaba, Thomas Fink, Laura Rottner, Peter Wohlmuth, Britta Goldmann, Feifan Ouyang, Karl-Heinz Kuck, Andreas Metzner ········· 974 22. Surface Electrocardiogram Screening for Subcutaneous Implantable Cardioverter-Defibrillators in Japanese Patients With and Without Brugada Syndrome Mihoko Kawabata, Masahiko Goya, Takeshi Sasaki, Shingo Maeda, Atsuhiko Yagishita, Yasuhiro Shirai, Masakazu Kaneko, Shinya Shiohira, Mitsuaki Isobe, Kenzo Hirao ········· 981 23. Superior Rhythm Discrimination With the SmartShock Technology Algorithm ― Results of the Implantable Defibrillator With Enhanced Features and Settings for Reduction of Inaccurate Detection (DEFENSE) Trial ― Yasushi Oginosawa, Ritsuko Kohno, Toshihiro Honda, Kan Kikuchi, Masatsugu Nozoe, Takayuki Uchida, Hitoshi Minamiguchi, Koichiro Sonoda, Masahiro Ogawa, Takeshi Ideguchi, Yoshihisa Kizaki, Toshihiro Nakamura, Kageyuki Oba, Satoshi Higa, Keiki Yoshida, Soichi Tsunoda, Yoshihisa Fujino, Haruhiko Abe ········· 1272 24. Current Status and Outcomes of Direct Oral Anticoagulant Use in Real-World Atrial Fibrillation Patients ― Fushimi AF Registry ― Yugo Yamashita, Ryuji Uozumi, Yasuhiro Hamatani, Masahiro Esato, Yeong-Hwa Chun, Hikari Tsuji, Hiromichi Wada, Koji Hasegawa, Hisashi Ogawa, Mitsuru Abe, Satoshi Morita, Masaharu Akao ········· 1278 25. Predictors of Mortality, Rehospitalization for Syncope and Cardiovascular Events in Patients With Cardiovascular Syncope Tatsuya Onuki, Makoto Shoji, Yuya Nakamura, Ko Ogawa, Akinori Ochi, Koichiro Inokuchi, Shiro Kawasaki, Yoshimi Onishi, Yoshimasa Onuma, Yumi Munetsugu, Miwa Kikuchi, Hiroyuki Ito, Yoshino Minoura, Norikazu Watanabe, Taro Adachi, Mitsuharu Kawamura, Taku Asano, Kaoru Tanno, Youichi Kobayashi ········· 1395 26. Sex-Related Differences in the Clinical Events of Patients With Atrial Fibrillation ― The Fushimi AF Registry ― Hisashi Ogawa, Yasuhiro Hamatani, Kosuke Doi, Yuji Tezuka, Yoshimori An, Mitsuru Ishii, Moritake Iguchi, Nobutoyo Masunaga, Masahiro Esato, Yeong-Hwa Chun, Hikari Tsuji, Hiromichi Wada, Koji Hasegawa, Mitsuru Abe, Gregory YH Lip, Masaharu Akao on behalf of the Fushimi AF Registry Investigators ········· 1403 27. Ranolazine Facilitates Termination of Ventricular Tachyarrhythmia Associated With Acute Myocardial Ischemia Through Suppression of Late INa-Mediated Focal Activity Takashi Ogawa, Haruo Honjo, Masatoshi Yamazaki, Yasunori Kushiyama, Ichiro Sakuma, Itsuo Kodama, Kaichiro Kamiya ········· 1411 28. Development of a Basic Risk Score for Incident Atrial Fibrillation in a Japanese General Population ― The Suita Study ― Yoshihiro Kokubo, Makoto Watanabe, Aya Higashiyama, Yoko M Nakao, Kengo Kusano, Yoshihiro Miyamoto ········· 1580 29. Performance of Leadless Pacemaker in Japanese Patients vs. Rest of the World ― Results From a Global Clinical Trial ― Kyoko Soejima, Taku Asano, Toshiyuki Ishikawa, Kengo Kusano, Toshiaki Sato, Hideo Okamura, Katsumi Matsumoto, Wataru Taguchi, Kurt Stromberg, Jeff Lande, Youichi Kobayashi, Micra Transcatheter Pacing Study Group ········· 1589 30. Automated Ablation Annotation Algorithm Reduces Re-conduction of Isolated Pulmonary Vein and Improves Outcome After Catheter Ablation for Atrial Fibrillation Nobuaki Tanaka, Koichi Inoue, Koji Tanaka, Yuko Toyoshima, Takafumi Oka, Masato Okada, Hiroyuki Inoue, Ryo Nakamaru, Yasushi Koyama, Atsunori Okamura, Katsuomi Iwakura, Yasushi Sakata, Kenshi Fujii ········· 1596 31. Efficacy of Intensive Radiofrequency Energy Delivery to the Localized Dense Scar Area in Post-Infarction Ventricular Tachycardia Ablation ― A Comparative Study With Standard Strategy Targeting the Infarcted Border Zone ― Kenji Kuroki, Akihiko Nogami, Kentaro Yoshida, Masahiko Goya, Masato Fukunaga, Kazuaki Kaitani, Naoaki Onishi, Takanao Mine, Takashi Koyama, Masayuki Igawa, Takeshi Machino, Hiro Yamasaki, Dongzhu Xu, Miyako Igarashi, Nobuyuki Murakoshi, Yukio Sekiguchi, Kazutaka Aonuma ········· 1603 32. Development of a Patient-Derived Induced Pluripotent Stem Cell Model for the Investigation of SCN5A-D1275N- Related Cardiac Sodium Channelopathy Mamoru Hayano, Takeru Makiyama, Tsukasa Kamakura, Hiroshi Watanabe, Kenichi Sasaki, Shunsuke Funakoshi, Yimin Wuriyanghai, Suguru Nishiuchi, Takeshi Harita, Yuta Yamamoto, Hirohiko Kohjitani, Sayako Hirose, Fumika Yokoi, Jiarong Chen, Osamu Baba, Takahiro Horie, Kazuhisa Chonabayashi, Seiko Ohno, Futoshi Toyoda, Yoshinori Yoshida, Koh Ono, Minoru Horie, Takeshi Kimura ········· 1783 33. Use of CHA2DS2-VASc Score to Predict New-Onset Atrial Fibrillation in Chronic Obstructive Pulmonary Disease Patients ― Large-Scale Longitudinal Study ― Wei-Syun Hu, Cheng-Li Lin ········· 1792 34. Survival and Heart Failure Hospitalization in Patients With Cardiac Resynchronization Therapy With or Without a Defibrillator for Primary Prevention in Japan ― Analysis of the Japan Cardiac Device Treatment Registry Database ― Hisashi Yokoshiki, Akihiko Shimizu, Takeshi Mitsuhashi, Hiroshi Furushima, Yukio Sekiguchi, Tetsuyuki Manaka, Nobuhiro Nishii, Takeshi Ueyama, Norishige Morita, Hideo Okamura, Takashi Nitta, Kenzo Hirao, Ken Okumura for the Members of the Implantable Cardioverter-Defibrillator (ICD) Committee of the Japanese Heart Rhythm Society ········· 1798
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35. Electrophysiological Characteristics and Radiofrequency Catheter Ablation Treatment of Idiopathic Ventricular Arrhythmias Successfully Ablated From the Ostium of the Coronary Sinus Yoshiaki Yui, Yukio Sekiguchi, Akihiko Nogami, Hiro Yamasaki, Takeshi Machino, Kenji Kuroki, Miyako Igarashi, Kazutaka Aonuma ········· 1807 Cardiovascular Intervention (15) 36. Regional Variation in the Use of Percutaneous Coronary Intervention in Japan Takahiro Inoue, Hiroyo Kuwabara, Kiyohide Fushimi ········· 195 37. Shock Index More Sensitive Than Cardiogenic Shock in ST-Elevation Myocardial Infarction Treated by Primary Percutaneous Coronary Intervention Veemal V. Hemradj, Jan Paul Ottervanger, Menko Jan de Boer, Harry Suryapranata for the Zwolle Myocardial Infarction Study Group ········· 199 38. Difference of Tissue Characteristics Between Early and Late Restenosis After Second-Generation Drug-Eluting Stents Implantation ― An Optical Coherence Tomography Study ― Hiroyuki Jinnouchi, Shoichi Kuramitsu, Tomohiro Shinozaki, Yusuke Tomoi, Takashi Hiromasa, Yohei Kobayashi, Takenori Domei, Yoshimitsu Soga, Makoto Hyodo, Shinichi Shirai, Kenji Ando ········· 450 39. Ad hoc vs. Non-ad hoc Percutaneous Coronary Intervention Strategies in Patients With Stable Coronary Artery Disease Toshiaki Toyota, Takeshi Morimoto, Hiroki Shiomi, Kenji Ando, Koh Ono, Satoshi Shizuta, Takao Kato, Naritatsu Saito, Yutaka Furukawa, Yoshihisa Nakagawa, Minoru Horie, Takeshi Kimura on behalf of the CREDO-Kyoto PCI/CABG Registry Cohort-2 Investigators ········· 458 40. Impact of Vessel Diameter Measured by Preprocedural Computed Tomography Angiography on Immediate and Late Outcomes of Endovascular Therapy for Iliac Artery Diseases Sung-Jin Hong, Young-Guk Ko, Dong-Ho Shin, Jung-Sun Kim, Byeong-Keuk Kim, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang ········· 675 41. Applicability of 3-Dimensional Quantitative Coronary Angiography-Derived Computed Fractional Flow Reserve for Intermediate Coronary Stenosis Kyoichiro Yazaki, Masato Otsuka, Shohei Kataoka, Mitsuru Kahata, Asako Kumagai, Koji Inoue, Hiroshi Koganei, Kenji Enta, Yasuhiro Ishii ········· 988 42. Clinical Outcomes of Repetition of Drug-Coated Balloon for Femoropopliteal Restenosis After Drug-Coated Balloon Treatment Shih-Jung Jang, Hsin-Hua Chou, Jyh-Ming Jimmy Juang, Chien-An Hsieh, De-Min Duan, Hsuan-Li Huang, Yu-Lin Ko ········· 993 43. Decreased Serum Albumin Predicts Bleeding Events in Patients on Antiplatelet Therapy After Percutaneous Coronary Intervention Yosuke Tatami, Hideki Ishii, Toshijiro Aoki, Kazuhiro Harada, Kenshi Hirayama, Yohei Shibata, Takuya Sumi, Yosuke Negishi, Kazuhiro Kawashima, Ayako Kunimura, Toshiki Kawamiya, Dai Yamamoto, Susumu Suzuki, Toyoaki Murohara ········· 999 44. QRS Score at Presentation Electrocardiogram Is Correlated With Infarct Size and Mortality in ST-Segment Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention Hiroki Shiomi, Masami Kosuge, Takeshi Morimoto, Hiroki Watanabe, Tomohiko Taniguchi, Kenji Nakatsuma, Toshiaki Toyota, Erika Yamamoto, Satoshi Shizuta, Tomohisa Tada, Yutaka Furukawa, Yoshihisa Nakagawa, Kenji Ando, Kazushige Kadota, Kazuo Kimura, Takeshi Kimura on behalf of the CREDO-Kyoto AMI Investigators ········· 1129 45. Predictors of Recurrent In-Stent Restenosis After Paclitaxel-Coated Balloon Angioplasty Hiroshi Koiwaya, Nozomi Watanabe, Nehiro Kuriyama, Shun Nishino, Kenji Ogata, Toshiyuki Kimura, Tatsuya Nakama, Hirohide Matsuura, Makoto Furugen, Yoshisato Shibata ········· 1286 46. Independent and Combined Effects of Serum Albumin and C-Reactive Protein on Long-Term Outcomes of Patients Undergoing Percutaneous Coronary Intervention Hideki Wada, Tomotaka Dohi, Katsumi Miyauchi, Shinichiro Doi, Ryo Naito, Hirokazu Konishi, Shuta Tsuboi, Manabu Ogita, Takatoshi Kasai, Shinya Okazaki, Kikuo Isoda, Satoru Suwa, Hiroyuki Daida ········· 1293 47. One-Year Outcome of Fractional Flow Reserve-Based Coronary Intervention in Japanese Daily Practice ― CVIT- DEFER Registry ― Nobuhiro Tanaka, Masato Nakamura, Takashi Akasaka, Kazushige Kadota, Shirou Uemura, Tetsuya Amano, Nobuo Shiode, Yoshihiro Morino, Kenshi Fujii, Yutaka Hikichi for the CVIT-DEFER Registry Investigators ········· 1301 48. Atrial Septostomy for Left Atrial Decompression During Extracorporeal Membrane Oxygenation by Inoue Balloon Catheter Yen-Nien Lin, Yin-Huei Chen, Huang-Joe Wang, Jui-Sung Hung, Kuan-Cheng Chang, Ping-Han Lo ········· 1419 49. Effect of Ezetimibe on Stabilization and Regression of Intracoronary Plaque ― The ZIPANGU Study ― Yasunori Ueda, Takafumi Hiro, Atsushi Hirayama, Sei Komatsu, Hiroshi Matsuoka, Tadateru Takayama, Masaharu Ishihara, Takatoshi Hayashi, Satoshi Saito, Kazuhisa Kodama for the ZIPANGU Investigators ········· 1611 50. Prevalence of Thin-Cap Fibroatheroma in Relation to the Severity of Anatomical and Physiological Stenosis Eisuke Usui, Taishi Yonetsu, Tadashi Murai, Yoshihisa Kanaji, Junji Matsuda, Masahiro Hoshino, Makoto Araki, Takayuki Niida, Masahiro Hada, Sadamitsu Ichijyo, Rikuta Hamaya, Yoshinori Kanno, Tetsumin Lee, Mitsuaki Isobe, Tsunekazu Kakuta ········· 1816
Circulation Journal Vol.81, December 2017 Contents of Volume 81, 2017 ix
Cardiac Rehabilitation (2) 51. Improvement in Exercise Capacity by Exercise Training Associated With Favorable Clinical Outcomes in Advanced Heart Failure With High B-Type Natriuretic Peptide Level Michio Nakanishi, Kazuhiro Nakao, Leon Kumasaka, Tetsuo Arakawa, Shigefumi Fukui, Takahiro Ohara, Masanobu Yanase, Teruo Noguchi, Satoshi Yasuda, Yoichi Goto ········· 1307 52. Underuse of Cardiac Rehabilitation in Workers With Coronary Artery Disease ― Claims Database Survey in Japan ― Natsuko Kanazawa, Kenji Ueshima, Shinjiro Tominari, Takeo Nakayama ········· 1424 Cardiovascular Surgery (13) 53. Glycated Hemoglobin and Risk of Sternal Wound Infection After Isolated Coronary Surgery Giuseppe Gatti, Andrea Perrotti, Daniel Reichart, Luca Maschietto, Francesco Onorati, Sidney Chocron, Magnus Dalén, Peter Svenarud, Giuseppe Faggian, Giuseppe Santarpino, Theodor Fischlein, Aniello Pappalardo, Daniele Maselli, Carmelo Dominici, Saverio Nardella, Antonino S. Rubino, Marisa De Feo, Francesco Santini, Francesco Nicolini, Riccardo Gherli, Giovanni Mariscalco, Tuomas Tauriainen, Eeva-Maija Kinnunen, Vito G. Ruggieri, Matteo Saccocci, Fausto Biancari ········· 36 54. Long-Term Clinical Outcomes and Prognostic Factors After Pericardiectomy for Constrictive Pericarditis in a Japanese Population Shunsuke Nishimura, Chisato Izumi, Masashi Amano, Sari Imamura, Naoaki Onishi, Yodo Tamaki, Soichiro Enomoto, Makoto Miyake, Toshihiro Tamura, Hirokazu Kondo, Kazuaki Kaitani, Kazuo Yamanaka, Yoshihisa Nakagawa ········· 206 55. Tricuspid Valve Replacement vs. Repair in Severe Tricuspid Regurgitation Hyoung Woo Chang, Dong Seop Jeong, Yang Hyun Cho, Kiick Sung, Wook Sung Kim, Young Tak Lee, Pyo Won Park ········· 330 56. Reducing Prosthesis-Patient Mismatch With Edwards Magna Prosthesis for Aortic Valve Replacement Yuta Kume, Tomoyuki Fujita, Satsuki Fukushima, Hiroki Hata, Yusuke Shimahara, Yorihiko Matsumoto, Kizuku Yamashita, Junjiro Kobayashi ········· 468 57. Long-Term Outcome of Cardiac Surgery in 1,040 Liver Cirrhosis Patient ― Nationwide Population-Based Cohort Study ― An-Hsun Chou, Tien-Hsing Chen, Chun-Yu Chen, Shao-Wei Chen, Chao-Wei Lee, Chien-Hung Liao, Shang-Yu Wang ········· 476 58. Five-Year Clinical Outcome of Asymptomatic vs. Symptomatic Severe Aortic Stenosis After Aortic Valve Replacement Shinichi Shirai, Tomohiko Taniguchi, Takeshi Morimoto, Kenji Ando, Kengo Korai, Kenji Minakata, Michiya Hanyu, Fumio Yamazaki, Tadaaki Koyama, Tatsuhiko Komiya, Norio Kanamori, Koichiro Murata, Takeshi Kitai, Yuichi Kawase, Chisato Izumi, Tsukasa Inada, Eri Minamino-Muta, Takao Kato, Moriaki Inoko, Katsuhisa Ishii, Naritatsu Saito, Kazuo Yamanaka, Noboru Nishiwaki, Hiroyuki Nakajima, Toshihiko Saga, Shogo Nakayama, Genichi Sakaguchi, Atsushi Iwakura, Kotaro Shiraga, Koji Ueyama, Keiichi Fujiwara, Senri Miwa, Junichiro Nishizawa, Mitsuru Kitano, Hitoshi Kitayama, Ryuzo Sakata, Takeshi Kimura on behalf of the CURRENT AS Registry Investigators ········· 485 59. Outcomes of Endovascular Repair of Aortoiliac Aneurysms and Analyses of Anatomic Suitability for Internal Iliac Artery Preserving Devices in Japanese Patients Nathan K Itoga, Naoki Fujimura, Keita Hayashi, Hideaki Obara, Hideyuki Shimizu, Jason T Lee ········· 682 60. Outcomes of Totally Endoscopic Atrial Septal Defect Closure Using a Glutaraldehyde-Treated Autologous Pericardial Patch Hidefumi Nishida, Daisuke Nakatsuka, Yuji Kawano, Nobuhiko Hiraiwa, Shuichiro Takanashi, Minoru Tabata ········· 689 61. Preoperative Serum Alkaline Phosphatase and Clinical Outcome of Off-Pump Coronary Artery Bypass Surgery Tae Kyong Kim, Deok Man Hong, Yoon Hyeong Choi, Chang-Hoon Koo, Youn Joung Cho, Jun-Bean Park, Kyung Woo Park, Hyo-Soo Kim, Yunseok Jeon ········· 799 62. Long-Term Outcomes of Suture vs. Ring Tricuspid Annuloplasty for Functional Tricuspid Regurgitation Hiroki Hata, Tomoyuki Fujita, Sayaka Miura, Yusuke Shimahara, Yuta Kume, Yorihiko Matsumoto, Kizuku Yamashita, Junjiro Kobayashi ········· 1432 63. Mitral Valve Structure in Addition to Myocardial Viability Determines the Outcome of Functional Mitral Regurgitation After Coronary Artery Bypass Grafting Shohei Yoshida, Satsuki Fukushima, Shigeru Miyagawa, Teruya Nakamura, Yasushi Yoshikawa, Hiroki Hata, Shunsuke Saito, Daisuke Yoshioka, Keitaro Domae, Noriyuki Kashiyama, Kouji Yamamoto, Ayumi Shintani, Satoshi Nakatani, Koichi Toda, Yoshiki Sawa ········· 1620 64. Long-Term Outcome of Aortic Root Remodeling for Patients With and Without Acute Aortic Dissection Takashi Kunihara, Niklas Neumann, Steffen Daniel Kriechbaum, Ryota Nomura, Hans-Joachim Schäfers ········· 1824 65. Predictors and Clinical Impact of Functional Mitral Stenosis Induced by Restrictive Annuloplasty for Ischemic and Functional Mitral Regurgitation Satoshi Kainuma, Kazuhiro Taniguchi, Koichi Toda, Toshihiro Funatsu, Haruhiko Kondoh, Shigeru Miyagawa, Yasushi Yoshikawa, Hiroki Hata, Shunsuke Saito, Takayoshi Ueno, Toru Kuratani, Takashi Daimon, Takafumi Masai, Yoshiki Sawa, Osaka Cardiovascular Surgery Research (OSCAR) Group ········· 1832
Circulation Journal Vol.81, December 2017 x Contents of Volume 81, 2017
Critical Care (4) 66. Efficacy of Precordial Percussion Pacing Assessed in a Cardiac Standstill Microminipig Model Takeshi Wada, Hiroshi Ohara, Yuji Nakamura, Xin Cao, Hiroko Izumi-Nakaseko, Kentaro Ando, Mitsuru Honda, Katsunori Yoshihara, Yuji Nakazato, Keith G. Lurie, Atsushi Sugiyama ········· 1137 67. Sudden Death Phenomenon While Bathing in Japan ― Mortality Data ― Masaru Suzuki, Takuro Shimbo, Toshiharu Ikaga, Shingo Hori ········· 1144 68. Useful Computed Tomography Score for Estimation of Early Neurologic Outcome in Post-Cardiac Arrest Patients With Therapeutic Hypothermia Kyu Sun Lee, Sung Eun Lee, Jun Young Choi, Yu-Rha Gho, Minjung Kathy Chae, Eun Jung Park, Mun Hee Choi, Ji Man Hong ········· 1628 69. Initial Blood Ammonia Level Is a Useful Prognostication Tool in Out-of-Hospital Cardiac Arrest ― Multicenter Prospective Study (SOS-KANTO 2012 Study) ― SOS-KANTO 2012 Study Group ········· 1839 Epidemiology (7) 70. Association Between Serum Vitamin D and All-Cause and Cause-Specific Death in a General Japanese Population ― The Hisayama Study ― Kaoru Umehara, Naoko Mukai, Jun Hata, Yoichiro Hirakawa, Tomoyuki Ohara, Daigo Yoshida, Hiro Kishimoto, Takanari Kitazono, Sumio Hoka, Yutaka Kiyohara, Toshiharu Ninomiya ········· 1315 71. Role of the Low-Density Lipoprotein-Cholesterol/High-Density Lipoprotein-Cholesterol Ratio in Predicting Serial Changes in the Lipid Component of Coronary Plaque Ryo Kawakami, Ichiro Matsumoto, Motoi Shiomi, Mizuki Kurozumi, Yuichi Miyake, Makoto Ishizawa, Kaori Ishikawa, Kazushi Murakami, Takahisa Noma, Yuichiro Takagi, Naoki Nishimoto, Tetsuo Minamino ········· 1439 72. Low Heart Rate Variability and Sympathetic Dominance Modifies the Association Between Insulin Resistance and Metabolic Syndrome ― The Toon Health Study ― Isao Saito, Koutatsu Maruyama, Eri Eguchi, Tadahiro Kato, Ryoichi Kawamura, Yasunori Takata, Hiroshi Onuma, Haruhiko Osawa, Takeshi Tanigawa ········· 1447 73. Incidence, Management and Short-Term Outcome of Stroke in a General Population of 1.4 Million Japanese ― Shiga Stroke Registry ― Naoyuki Takashima, Hisatomi Arima, Yoshikuni Kita, Takako Fujii, Naomi Miyamatsu, Masaru Komori, Yoshihisa Sugimoto, Satoru Nagata, Katsuyuki Miura, Kazuhiko Nozaki ········· 1636 74. Morning and Evening Blood Pressures Are Associated With Intima-Media Thickness in a General Population ― The Hisayama Study ― Satoko Sakata, Jun Hata, Masayo Fukuhara, Koji Yonemoto, Naoko Mukai, Daigo Yoshida, Hiro Kishimoto, Toshio Ohtsubo, Takanari Kitazono, Yutaka Kiyohara, Toshiharu Ninomiya ········· 1647 75. Association of Airflow Limitation With Carotid Atherosclerosis in a Japanese Community ― The Hisayama Study ― Kunihiro Kudo, Jun Hata, Koichiro Matsumoto, Yuki Shundo, Satoru Fukuyama, Hiromasa Inoue, Takanari Kitazono, Yutaka Kiyohara, Toshiharu Ninomiya, Yoichi Nakanishi ········· 1846 76. Temporal Trends in the Incidence and Clinical Features of Acute Myocardial Infarction in a Japanese Rural Area From 2006 to 2014 Motoyuki Nakamura, Fumitaka Tanaka, Toshie Segawa, Tomohiro Takahashi, Yuuki Matsuura, Toshiaki Sakai, Osamu Nishiyama, Masanobu Niiyama, Toshiyuki Onoda, Makoto Koshiyama (on behalf of Northern Iwate Heart Disease Registry Consortium) ········· 1854 Heart Failure (20) 77. Utility of High-Resolution Magnetocardiography to Predict Later Cardiac Events in Nonischemic Cardiomyopathy Patients With Normal QRS Duration Shoji Kawakami, Hiroshi Takaki, Shuji Hashimoto, Yoshitaka Kimura, Takahiro Nakashima, Takeshi Aiba, Kengo F. Kusano, Shiro Kamakura, Satoshi Yasuda, Masaru Sugimachi ········· 44 78. Impact of Plasma Kynurenine Level on Functional Capacity and Outcome in Heart Failure ― Results From Studies Investigating Co-morbidities Aggravating Heart Failure (SICA-HF) ― Masaaki Konishi, Nicole Ebner, Jochen Springer, Joerg C. Schefold, Wolfram Doehner, Thomas Bernd Dschietzig, Stefan D. Anker, Stephan von Haehling ········· 52 79. Predictive Value of QRS Duration at Admission for In-Hospital Clinical Outcome of Takotsubo Cardiomyopathy Tetsuo Yamaguchi, Tsutomu Yoshikawa, Toshiaki Isogai, Takamichi Miyamoto, Yuichiro Maekawa, Tetsuro Ueda, Konomi Sakata, Tsutomu Murakami, Takeshi Yamamoto, Ken Nagao, Morimasa Takayama ········· 62 80. Clinical Characteristics and Social Frailty of Super-Elderly Patients With Heart Failure ― The Kitakawachi Clinical Background and Outcome of Heart Failure Registry ― Kensuke Takabayashi, Akihiro Ikuta, Yoshinori Okazaki, Mariko Ogami, Kotaro Iwatsu, Koichi Matsumura, Tsutomu Ikeda, Tahei Ichinohe, Yuko Morikami, Takashi Yamamoto, Ryoko Fujita, Kotoe Takenaka, Hiroyuki Takenaka, Yoshisumi Haruna, Hiroyuki Muranaka, Masaaki Ozaki, Tetsuhisa Kitamura, Shouji Kitaguchi, Ryuji Nohara ········· 69 81. Higher Body Mass Index Increases Risk of HeartMate II Pump Thrombosis But Does Not Adversely Affect Long- Term Survival Jason J. Han, Renganaden Sooppan, Adam P. Johnson, Carol W. Chen, Ann C. Gaffey, Emily C. Phillips, Jessica Howard, J. Eduardo Rame, Michael A. Acker, Pavan Atluri ········· 213
Circulation Journal Vol.81, December 2017 Contents of Volume 81, 2017 xi
82. Riser Pattern Is a Novel Predictor of Adverse Events in Heart Failure Patients With Preserved Ejection Fraction Takahiro Komori, Kazuo Eguchi, Toshinobu Saito, Satoshi Hoshide, Kazuomi Kario ········· 220 83. Impact on Clinical Outcomes of Periodic Leg Movements During Sleep in Hospitalized Patients Following Acute Decompensated Heart Failure Shoichiro Yatsu, Takatoshi Kasai, Shoko Suda, Hiroki Matsumoto, Nanako Shiroshita, Mitsue Kato, Fusae Kawana, Azusa Murata, Takao Kato, Masaru Hiki, Hiroyuki Daida ········· 495 84. Long-Term Prognosis of Patients With Left Ventricular Noncompaction ― Comparison Between Infantile and Juvenile Types ― Ce Wang, Asami Takasaki, Sayaka Watanabe Ozawa, Hideyuki Nakaoka, Mako Okabe, Nariaki Miyao, Kazuyoshi Saito, Keijiro Ibuki, Keiichi Hirono, Naoki Yoshimura, Xianyi Yu, Fukiko Ichida ········· 694 85. Asymptomatic Cocaine Abuse ― Myocardial Tissue Characterization Using Cardiac Biomarkers and Cardiovascular Magnetic Resonance Imaging ― Ulf K. Radunski, Ulrike Fuger, Sebastian Bohnen, Gunnar K. Lund, Christian Stehning, Tanja Zeller, Enver Tahir, Maxim Avanesov, Gerhard Adam, Stefan Blankenberg, Jens Reimer, Kai Muellerleile ········· 701 86. Neurohumoral Modulation During Waon Therapy in Chronic Heart Failure ― Subanalysis of Waon-CHF Study ― Tomoko Ichiki, John C. Burnett Jr, Christopher G. Scott, Denise M. Heublein, Masaaki Miyata, Koichiro Kinugawa, Teruo Inoue, Chuwa Tei, WAON-CHF Study Investigators ········· 709 87. New-Onset Diabetes Mellitus After Heart Transplantation ― Incidence, Risk Factors and Impact on Clinical Outcome ― Ho Jin Kim, Sung-Ho Jung, Jae-Joong Kim, Tae-Jin Yun, Joon Bum Kim, Suk Jung Choo, Cheol Hyun Chung, Jae Won Lee ········· 806 88. B-Type Natriuretic Peptide in Heart Failure With Preserved Ejection Fraction ― Relevance to Age-Related Left Ventricular Modeling in Japanese ― Eisaku Harada, Yuji Mizuno, Fumihito Kugimiya, Makoto Shono, Hiroyuki Maeda, Naotsugu Yano, Koichiro Kuwahara, Hirofumi Yasue ········· 1006 89. Identification and Assessment of Cardiac Amyloidosis by Myocardial Strain Analysis of Cardiac Magnetic Resonance Imaging Seitaro Oda, Daisuke Utsunomiya, Takeshi Nakaura, Hideaki Yuki, Masafumi Kidoh, Kosuke Morita, Seiji Takashio, Megumi Yamamuro, Yasuhiro Izumiya, Kyoko Hirakawa, Toshifumi Ishida, Kenichi Tsujita, Mitsuharu Ueda, Taro Yamashita, Yukio Ando, Hiroyuki Hata, Yasuyuki Yamashita ········· 1014 90. Prediction of Both Electrical and Mechanical Reverse Remodeling on Acute Electrocardiogram Changes After Cardiac Resynchronization Therapy Chien-Ming Cheng, Chieh-Shou Su, Pesus Chou, Ying-Chieh Liao, Chi-Yen Wang, Jian-Rong Zhang, Yu-Cheng Hsieh, Tsu-Juey Wu, Yu-Wei Chen, Chi-Jen Weng, Keng-Hao Chang, Weihua Zhou, Guang-Uei Hung, Jin-Long Huang, Kenichi Nakajima ········· 1322 91. Gender Difference in the Prognostic Value of N-Terminal Pro-B Type Natriuretic Peptide in Patients With Heart Failure ― A Report From the Korean Heart Failure Registry (KorHF) ― Hack-Lyoung Kim, Myung-A Kim, Dong-Ju Choi, Seongwoo Han, Eun-Seok Jeon, Myeong-Chan Cho, Jae-Joong Kim, Byung-Su Yoo, Mi-Seung Shin, In-Whan Seong, Youngkeun Ahn, Seok-Min Kang, Young-Jo Kim, Hyung Seop Kim, Shung Chull Chae, Byung-Hee Oh, Myoung-Mook Lee, Kyu-Hyung Ryu on behalf of the Korean Heart Failure Registry ········· 1329 92. Imbalanced Angiogenesis in Peripartum Cardiomyopathy ― Diagnostic Value of Placenta Growth Factor ― Alexandre Mebazaa, Marie-France Seronde, Etienne Gayat, Kemi Tibazarwa, Dilly O.C. Anumba, Najla Akrout, Malha Sadoune, Jamela Sarb, Mattia Arrigo, Justina Motiejunaite, Said Laribi, Matthieu Legrand, Lydia Deschamps, Loubina Fazal, Lila Bouadma, Corinne Collet, Philippe Manivet, Alain Cohen Solal, Jean-Marie Launay, Jane-Lise Samuel, Karen Sliwa ········· 1654 93. Effect of Dipeptidyl Peptidase-4 Inhibitors on Cardiovascular Outcome and Cardiac Function in Patients With Diabetes and Heart Failure ― Insights From the Ibaraki Cardiac Assessment Study-Heart Failure (ICAS-HF) Registry ― Masayoshi Yamamoto, Yoshihiro Seo, Tomoko Ishizu, Isao Nishi, Yoshie Hamada-Harimura, Tomoko Machino-Ohtsuka, Kimi Sato, Seika Sai, Akinori Sugano, Kenichi Obara, Kazutaka Aonuma ········· 1662 94. Effect of Anemia on Cardiovascular Hemodynamics, Therapeutic Strategy and Clinical Outcomes in Patients With Heart Failure and Hemodynamic Congestion Muneyoshi Tanimura, Kaoru Dohi, Naoki Fujimoto, Keishi Moriwaki, Taku Omori, Yuichi Sato, Emiyo Sugiura, Naoto Kumagai, Shiro Nakamori, Tairo Kurita, Eitaro Fujii, Norikazu Yamada, Masaaki Ito ········· 1670 95. Differential Effects of Myocardial Afadin on Pressure Overload-Induced Compensated Cardiac Hypertrophy Dimitar P. Zankov, Akira Sato, Akio Shimizu, Hisakazu Ogita ········· 1862 96. Clinical Significance of Pulmonary Arterial Capacitance Calculated by Echocardiography in Patients With Advanced Heart Failure Yuki Saito, Tomohito Ohtani, Hidetaka Kioka, Toshinari Onishi, Yasumasa Tsukamoto, Kei Nakamoto, Tatsunori Taniguchi, Satoshi Nakatani, Atsushi Hirayama, Yasushi Sakata ········· 1871
Circulation Journal Vol.81, December 2017 xii Contents of Volume 81, 2017
Hypertension and Circulatory Control (5) 97. Effects of Salt Loading on Plasma Osteoprotegerin Levels and Protective Role of Potassium Supplement in Normotensive Subjects Fu-Qiang Liu, Sheng-Qiang Liu, Yong Zhang, Yang Wang, Chao Chu, Dan Wang, Shuo Pan, Jun-Kui Wang, Qi Yu, Jian-Jun Mu ········· 77 98. Neurohumoral and Endothelial Responses to Heated Water-Based Exercise in Resistant Hypertensive Patients Lais Galvani de Barros Cruz, Edimar Alcides Bocchi, Guido Grassi, Guilherme Veiga Guimaraes ········· 339 99. Impact of Hypertension and Subclinical Organ Damage on the Incidence of Cardiovascular Disease Among Japanese Residents at the Population and Individual Levels ― The Circulatory Risk in Communities Study (CIRCS) ― Akihiko Kitamura, Kazumasa Yamagishi, Hironori Imano, Masahiko Kiyama, Renzhe Cui, Tetsuya Ohira, Mitsumasa Umesawa, Isao Muraki, Tomoko Sankai, Isao Saito, Hiroyasu Iso on behalf of the CIRCS Investigators ········· 1022 100. Differences in Dynamic Diurnal Blood Pressure Variability Between Japanese and American Treatment-Resistant Hypertensive Populations Kazuomi Kario, Deepak L. Bhatt, Sandeep Brar, George L. Bakris ········· 1337 101. Comparison of Prognostic Values of Daytime and Night-Time Systolic Blood Pressures on Renal Outcomes in Patients With Chronic Kidney Disease Eisuke Katafuchi, Masaru Nakayama, Shigeru Tanaka, Teppei Sakoh, Ryota Yoshitomi, Akiko Fukui, Makiko Seki, Yusuke Nakamata, Mitsuhiro Tominaga, Kazuhiko Tsuruya, Takanari Kitazono ········· 1454 Imaging (7) 102. Reconsideration of Inferior Vena Cava Parameters for Estimating Right Atrial Pressure in an East Asian Population ― Comparative Simultaneous Ultrasound-Catheterization Study ― Takayuki Kawata, Masao Daimon, Seitetsu L. Lee, Koichi Kimura, Naoko Sawada, Shuo-Ju Chiang, Keitaro Mahara, Takeshi Okubo, Tomoko Nakao, Megumi Hirokawa, Boqing Xu, Tomoko S. Kato, Masafumi Watanabe, Yutaka Yatomi, Issei Komuro ········· 346 103. Nuclear Cardiology Practice in Asia: Analysis of Radiation Exposure and Best Practice for Myocardial Perfusion Imaging ― Results From the IAEA Nuclear Cardiology Protocols Cross-Sectional Study (INCAPS) ― Thomas N.B. Pascual, Mathew Mercuri, Noura El-Haj, Henry Hee-Sung Bom, Vikram Lele, Mouaz H. Al-Mallah, Osnat Luxenburg, Ganesan Karthikeyan, Joao Vitola, John J. Mahmarian, Nathan Better, Leslee J. Shaw, Madan M. Rehani, Ravi Kashyap, Diana Paez, Maurizio Dondi, Andrew J. Einstein for the INCAPS Investigators Group ········· 501 104. Assessment of Left Ventricular Function and Mass on Free-Breathing Compressed Sensing Real-Time Cine Imaging Tomoyuki Kido, Teruhito Kido, Masashi Nakamura, Kouki Watanabe, Michaela Schmidt, Christoph Forman, Teruhito Mochizuki ········· 1463 105. Antiplatelet Drug Regimen in Patients With Stent Thrombosis ― Insights From the PESTO French Optical Coherence Tomography Registry ― Nicolas Amabile, Guillaume Cayla, Pascal Motreff, Charlotte Trouillet, Grégoire Range, Olivier Dubreuil, Estelle Vautrin, François Derimay, Lionel Mangin, Nicolas Meneveau, Christophe Caussin, Géraud Souteyrand ········· 1469 106. Achilles Tendon Ultrasonography for Diagnosis of Familial Hypercholesterolemia Among Japanese Subjects Masahito Michikura, Masatsune Ogura, Masahiro Yamamoto, Masahiko Sekimoto, Chizuru Fuke, Mika Hori, Koji Arai, Shinji Kihara, Kiminori Hosoda, Koji Yanagi, Mariko Harada-Shiba ········· 1879 107. Detection of Ceramide, a Risk Factor for Coronary Artery Disease, in Human Coronary Plaques by Fluorescent Angioscopy Yasumi Uchida, Yasuto Uchida, Takanobu Kobayashi, Seiichiro Shirai, Nobuyuki Hiruta, Ei Shimoyama, Tsuyoshi Tabata ········· 1886 108. Myocardial Bridges on Coronary Computed Tomography Angiography ― Correlation With Intravascular Ultrasound and Fractional Flow Reserve ― Signe Helene Forsdahl, Ian S. Rogers, Ingela Schnittger, Shigemitsu Tanaka, Takumi Kimura, Vedant S. Pargaonkar, Frandics P. Chan, Dominik Fleischmann, Jennifer A. Tremmel, Hans-Christoph Becker ········· 1894 Ischemic Heart Disease (26) 109. Prospective Identification of Stent Fracture by Enhanced Stent Visualization System During Percutaneous Coronary Intervention Simone Biscaglia, Matteo Tebaldi, Carlo Tumscitz, Rita Pavasini, Jlenia Marchesini, Francesco Gallo, Giosafat Spitaleri, Fatima Zaraket, Matteo Serenelli, Paolo Cimaglia, Giulia Bugani, Gianluca Campo ········· 82 110. Preprocedural High-Sensitivity C-Reactive Protein Predicts Long-Term Outcome of Percutaneous Coronary Intervention Hideki Wada, Tomotaka Dohi, Katsumi Miyauchi, Jun Shitara, Hirohisa Endo, Shinichiro Doi, Ryo Naito, Hirokazu Konishi, Shuta Tsuboi, Manabu Ogita, Takatoshi Kasai, Ahmed Hassan, Shinya Okazaki, Kikuo Isoda, Kazunori Shimada, Satoru Suwa, Hiroyuki Daida ········· 90 111. Variant Aldehyde Dehydrogenase 2 (ALDH2*2) in East Asians Interactively Exacerbates Tobacco Smoking Risk for Coronary Spasm ― Possible Role of Reactive Aldehydes ― Yuji Mizuno, Seiji Hokimoto, Eisaku Harada, Kenji Kinoshita, Michihiro Yoshimura, Hirofumi Yasue ········· 96
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112. Value of 3-Dimensional Speckle Tracking Echocardiography in the Prediction of Microvascular Obstruction and Left Ventricular Remodeling in Patients With ST-Elevation Myocardial Infarction Akinori Sugano, Yoshihiro Seo, Tomoko Ishizu, Hiroaki Watabe, Masayoshi Yamamoto, Tomoko Machino-Ohtsuka, Yui Takaiwa, Yuki Kakefuda, Hideaki Aihara, Yuko Fumikura, Hidetaka Nishina, Yuichi Noguchi, Kazutaka Aonuma ········· 353 113. Impact of Morning Onset on the Incidence of Recurrent Acute Coronary Syndrome and Progression of Coronary Atherosclerosis in Acute Myocardial Infarction Hiroshi Nakashima, Yuka Mashimo, Masaya Kurobe, Shigenori Muto, Shinnosuke Furudono, Koji Maemura ········· 361 114. Association Between Prior Aspirin Use and Morphological Features of Culprit Lesions at First Presentation of Acute Coronary Syndrome Assessed by Optical Coherence Tomography Taishi Yonetsu, Tetsumin Lee, Tadashi Murai, Yoshinori Kanno, Rikuta Hamaya, Sadamitsu Ichijo, Takayuki Niida, Masahiro Hada, Makoto Araki, Junji Matsuda, Eisuke Usui, Masahiro Hoshino, Yoshihisa Kanaji, Tsunekazu Kakuta ········· 511 115. Age-Specific Trends in the Incidence and In-Hospital Mortality of Acute Myocardial Infarction Over 30 Years in Japan — Report From the Miyagi AMI Registry Study — Yuanji Cui, Kiyotaka Hao, Jun Takahashi, Satoshi Miyata, Tomohiko Shindo, Kensuke Nishimiya, Yoku Kikuchi, Ryuji Tsuburaya, Yasuharu Matsumoto, Kenta Ito, Yasuhiko Sakata, Hiroaki Shimokawa ········· 520 116. Barriers Associated With Door-to-Balloon Delay in Contemporary Japanese Practice Nobuhiro Ikemura, Mitsuaki Sawano, Yasuyuki Shiraishi, Ikuko Ueda, Hiroaki Miyata, Yohei Numasawa, Shigetaka Noma, Masahiro Suzuki, Yukihiko Momiyama, Taku Inohara, Kentaro Hayashida, Shinsuke Yuasa, Yuichiro Maekawa, Keiichi Fukuda, Shun Kohsaka ········· 815 117. Relationship Between γ-Glutamyltransferase Levels and Left Ventricular Diastolic Dysfunction Seungho Ryu, Yoosoo Chang, Jeonggyu Kang, Min-Jung Kwon, Kyung Eun Yun, Hyun-Suk Jung, Chan-Won Kim, Hocheol Shin, Ki-Chul Sung ········· 823 118. Differential Incidence and Morphology of Spasm According to Coronary Arterial Location by Intracoronary Ergonovine Spasm Provocation Testing Shozo Sueda, Hiroaki Kohno ········· 831 119. Association of Toll-Like Receptor 4 on Human Monocyte Subsets and Vulnerability Characteristics of Coronary Plaque as Assessed by 64-Slice Multidetector Computed Tomography Yuichi Ozaki, Toshio Imanishi, Seiki Hosokawa, Tsuyoshi Nishiguchi, Akira Taruya, Takashi Tanimoto, Akio Kuroi, Takashi Yamano, Yoshiki Matsuo, Yasushi Ino, Hironori Kitabata, Takashi Kubo, Atsushi Tanaka, Takashi Akasaka ········· 837 120. Circulating Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Concentration and Risk of Cardiovascular Events ― Systematic Review and Meta-Analysis of Prospective Studies ― Yunjun Xiao, Chaoqiong Peng, Wei Huang, Jinzhou Zhang, Yang Gao, Jean H. Kim, Eng-kiong Yeoh, Xuefen Su ········· 1150 121. Risk of Ischemic Stroke in Patients With Non-Valvular Atrial Fibrillation Not Receiving Oral Anticoagulants ― Korean Nationwide Population-Based Study ― Si-Hyuck Kang, Eue-Keun Choi, Kyung-Do Han, So-Ryoung Lee, Woo-Hyun Lim, Myung-Jin Cha, Youngjin Cho, Il-Young Oh, Seil Oh ········· 1158 122. Coronary Atherosclerotic Plaque Characteristics and Cardiovascular Risk Factors ― Insights From an Optical Coherence Tomography Study ― Roberta De Rosa, Mariuca Vasa-Nicotera, David M. Leistner, Sophia M. Reis, Claudia E. Thome, Jes-Niels Boeckel, Stephan Fichtlscherer, Andreas M. Zeiher ········· 1165 123. Colchicine Improves Survival, Left Ventricular Remodeling, and Chronic Cardiac Function After Acute Myocardial Infarction Koichiro Fujisue, Koichi Sugamura, Hirofumi Kurokawa, Junichi Matsubara, Masanobu Ishii, Yasuhiro Izumiya, Koichi Kaikita, Seigo Sugiyama ········· 1174 124. Early Repolarization Pattern Predicts the Increased Risk of Ventricular Arrhythmias in Patients With Acute Anterior ST-Segment Elevation Myocardial Infarction ― A Propensity Analysis ― Qi Chen, Mingqi Zheng, Gang Liu, Xiangmin Shi, Ran Zhang, Xiao Zhou, Yutao Xi, Junping Sun, Chao Zhu, Yundai Chen, Jie Cheng, Junxiang Yin ········· 1346 125. Diagnostic Accuracy of Endocardial-to-Epicardial Myocardial Blood Flow Ratio for the Detection of Significant Coronary Artery Disease With Dynamic Myocardial Perfusion Dual-Source Computed Tomography Yoshitaka Goto, Kakuya Kitagawa, Mio Uno, Shiro Nakamori, Tatsuro Ito, Naoki Nagasawa, Kaoru Dohi, Hajime Sakuma ········· 1477 126. Epidemiology of Myocardial Infarction Caused by Presumed Paradoxical Embolism via a Patent Foramen Ovale Franz X. Kleber, Telse Hauschild, Antonia Schulz, Anne Winkelmann, Leonhard Bruch ········· 1484 127. Effect of Reverse Vessel Remodeling on Regression of Coronary Atherosclerosis in Patients Treated With Aggressive Lipid- and Blood Pressure-Lowering Therapy ― Insight From MILLION Study ― Tadatsugu Gamou, Kenji Sakata, Hayato Tada, Tetsuo Konno, Kenshi Hayashi, Hidekazu Ino, Masakazu Yamagishi, Masa-aki Kawashiri on behalf of the MILLION Study Group ········· 1490
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128. Efficacy and Safety of Bococizumab (RN316/PF-04950615), a Monoclonal Antibody Against Proprotein Convertase Subtilisin/Kexin Type 9, in Hypercholesterolemic Japanese Subjects Receiving a Stable Dose of Atorvastatin or Treatment-Naive ― Results From a Randomized, Placebo-Controlled, Dose-Ranging Study ― Koutaro Yokote, Shigeto Kanada, Osamu Matsuoka, Hisakuni Sekino, Keiji Imai, Junichi Tabira, Nobushige Matsuoka, Sandip Chaudhuri, Tamio Teramoto ········· 1496 129. Prognostic Value of Combination of Plasma D-Dimer Concentration and Estimated Glomerular Filtration Rate in Predicting Long-Term Mortality of Patients With Stable Coronary Artery Disease Hiroyuki Naruse, Junnichi Ishii, Hiroshi Takahashi, Fumihiko Kitagawa, Ryuunosuke Okuyama, Hideki Kawai, Takashi Muramatsu, Masahide Harada, Akira Yamada, Sadako Motoyama, Shigeru Matsui, Mutsuharu Hayashi, Masayoshi Sarai, Eiichi Watanabe, Hideo Izawa, Yukio Ozaki ········· 1506 130. Stent Fracture and Peri-Stent Contrast Staining After Everolimus-Eluting Stent Implantation ― 5-Year Outcomes ― Katsuya Miura, Takeshi Tada, Akinune Kuwayama, Takenobu Shimada, Masanobu Ohya, Hidewo Amano, Shunsuke Kubo, Yusuke Hyodo, Suguru Otsuru, Seiji Habara, Hiroyuki Tanaka, Yasushi Fuku, Tsuyoshi Goto, Kazushige Kadota ········· 1514 131. Dynamics of Oxidative Stress Evoked by Myocardial Ischemia Reperfusion After Off-Pump Coronary Artery Bypass Grafting Elucidated by Bilirubin Oxidation Masaki Yamamoto, Hideaki Nishimori, Takashi Fukutomi, Tokio Yamaguchi, Kazumasa Orihashi ········· 1678 132. Efficacy and Safety of Cholesteryl Ester Transfer Protein Inhibitor Evacetrapib Administered as Monotherapy in Japanese Patients With Primary Hypercholesterolemia Tamio Teramoto, Arihiro Kiyosue, Takeshi Iimura, Yasushi Takita, Jeffrey S. Riesmeyer, Masahiro Murakami ········· 1686 133. Impact of Door-to-Balloon Time in Patients With ST-Elevation Myocardial Infarction Who Arrived by Self- Transport ― Acute Myocardial Infarction-Kyoto Multi-Center Risk Study Group ― Naotoshi Kodama, Takeshi Nakamura, Kenji Yanishi, Naohiko Nakanishi, Kan Zen, Tetsuhiro Yamano, Hirokazu Shiraishi, Takeshi Shirayama, Jun Shiraishi, Takahisa Sawada, Yoshio Kohno, Makoto Kitamura, Keizo Furukawa, Satoaki Matoba ········· 1693 134. Depleted Leukocyte Mitochondrial DNA Copy Number Correlates With Unfavorable Left Ventricular Volumetric and Spherical Shape Remodeling in Acute Myocardial Infarction After Primary Angioplasty Ching-Hui Huang, Chen-Ling Kuo, Ching-San Huang, Chin-San Liu, Chia-Chu Chang ········· 1901 Metabolic Disorder (2) 135. One-Year Efficacy and Safety of Evolocumab in Japanese Patients ― A Pooled Analysis From the Open-Label Extension OSLER Studies ― Atsushi Hirayama, Shizuya Yamashita, Hyoe Inomata, Helina Kassahun, Marcoli Cyrille, Andrea Ruzza, Masayuki Yoshida, Arihiro Kiyosue, Yuhui Ma, Tamio Teramoto ········· 1029 136. Association Between Waist-to-Height Ratio and Endothelial Dysfunction in Patients With Morbidity ― A Report From the FMD-J Study ― Akihiro Tokushige, Shinichiro Ueda, Hirofumi Tomiyama, Mituru Ohishi, Takahide Kohro, Yukihito Higashi, Bonpei Takase, Toru Suzuki, Tomoko Ishizu, Tsutomu Yamazaki, Tomoo Furumoto, Kazuomi Kario, Teruo Inoue, Shinji Koba, Yasuhiko Takemoto, Takuzo Hano, Masataka Sata, Yutaka Ishibashi, Koichi Node, Koji Maemura, Yusuke Ohya, Taiji Furukawa, Hiroshi Ito, Akira Yamashina ········· 1911 Myocardial Disease (2) 137. Biphasic Force-Frequency Relation Predicts Primary Cardiac Events in Patients With Hypertrophic Cardiomyopathy Ryota Morimoto, Takahiro Okumura, Yasuko K. Bando, Kenji Fukaya, Akinori Sawamura, Haruya Kawase, Shinya Shimizu, Shuzo Shimazu, Akihiro Hirashiki, Kyosuke Takeshita, Toyoaki Murohara ········· 368 138. Three-Dimensional Left Ventricular Torsion in Patients With Dilated Cardiomyopathy ― A Marker of Disease Severity ― Krunoslav Michael Sveric, Stefan Ulbrich, Mohamed Rady, Tobias Ruf, Heda Kvakan, Ruth H. Strasser, Stefanie Jellinghaus ········· 529 Pediatric Cardiology and Adult Congenital Heart Disease (8) 139. Prognostic Significance of QT Interval Dispersion in the Response to Intravenous Immunoglobulin Therapy in Kawasaki Disease Noriko Motoki, Yohei Akazawa, Shoko Yamazaki, Akira Hachiya, Hirohiko Motoki, Satoshi Matsuzaki, Kenichi Koike ········· 537 140. Comparison of Clinical Outcomes After Transcatheter vs. Minimally Invasive Cardiac Surgery Closure for Atrial Septal Defect Masaki Kodaira, Akio Kawamura, Kazuma Okamoto, Hideaki Kanazawa, Yugo Minakata, Mitsushige Murata, Hideyuki Shimizu, Keiichi Fukuda ········· 543 141. Endothelial Function in Children and Adolescents Is Mainly Influenced by Age, Sex and Physical Activity ― An Analysis of Reactive Hyperemic Peripheral Artery Tonometry ― Ulrike M. Mueller, Claudia Walther, Jennifer Adam, Kati Fikenzer, Sandra Erbs, Meinhard Mende, Volker Adams, Axel Linke, Gerhard Schuler ········· 717 142. Mid-Term Follow-up of School-Aged Children With Borderline Long QT Interval Aya Miyazaki, Heima Sakaguchi, Yu Matsumura, Yosuke Hayama, Kanae Noritake, Jun Negishi, Etsuko Tsuda, Yoshihiro Miyamoto, Takeshi Aiba, Wataru Shimizu, Kengo Kusano, Isao Shiraishi, Hideo Ohuchi ········· 726
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143. Mechanisms of Left Ventricular Dysfunction Assessed by Layer-Specific Strain Analysis in Patients With Repaired Tetralogy of Fallot Mariko Yamada, Ken Takahashi, Maki Kobayashi, Kana Yazaki, Hirobumi Takayasu, Katsumi Akimoto, Masahiko Kishiro, Akio Inage, Tadahiro Yoshikawa, In-Sam Park, Keisuke Nakanishi, Shiori Kawasaki, Toshiaki Shimizu ········· 846 144. Impact of Surgery in Ebstein’s Anomaly Using Current Surgical Criteria Nydia Ávila-Vanzzini, Juan Francisco Fritche-Salazar, Héctor Herrera-Bello, Nilda Espinola-Zavaleta, Jorge Kuri Alfaro, Hugo Rodriguez-Zanella, Mirna Verónica Álvarez Bran, Jorge Cossio Aranda, Manuel B.A. Gaxiola Macias, Pedro Curi-Curi ········· 1354 145. Acute Kidney Injury Following Cardiopulmonary Bypass in Children ― Risk Factors and Outcomes ― Seon Hwa Lee, Soo-Jin Kim, Hyung Joong Kim, Jae Sung Son, Ran Lee, Tae Gyoon Yoon ········· 1522 146. Temporal Sequential Pattern of Right Ventricular Free Wall Contraction in Normal Children Yasunobu Hayabuchi, Akemi Ono, Yukako Homma, Shoji Kagami ········· 1699 Peripheral Vascular Disease (4) 147. Long-Term Outcomes After Percutaneous Lower Extremity Arterial Interventions With Atherectomy vs. Balloon Angioplasty ― Propensity Score-Matched Registry ― Adam Janas, Piotr P. Buszman, Krzysztof P. Milewski, Szymon Wiernek, Ksenia Janas, Maciej Pruski, Wojciech Wojakowski, Aleksandra Błachut, Wojciech Picheta, Pawel Buszman, Stefan Kiesz ········· 376 148. Short-Term Subcutaneous Fondaparinux and Oral Edoxaban for Acute Venous Thromboembolism Shinji Hisatake, Takayuki Kabuki, Shunsuke Kiuchi, Takashi Oka, Shintaro Dobashi, Takahiro Fujii, Yoshihiro Iwasaki, Takanori Ikeda ········· 855 149. Increasing Risk of Osteoporotic Fracture Is Associated With Vascular Dysfunction and Abnormal Vascular Structure in Both Men and Women Masato Kajikawa, Nozomu Oda, Shinji Kishimoto, Tatsuya Maruhashi, Yumiko Iwamoto, Akimichi Iwamoto, Shogo Matsui, Yoshiki Aibara, Farina Binti Mohamad Yusoff, Takayuki Hidaka, Yasuki Kihara, Kazuaki Chayama, Chikara Goto, Kensuke Noma, Ayumu Nakashima, Akira Taguchi, Yukihito Higashi ········· 862 150. Pilot Cohort Study Assessing the Efficacy of Endovascular Revascularization in the Restoration of Peripheral Sensory Disturbance in Patients With Critical Limb Ischemia Kentaro Jujo, Katsumi Saito, Issei Ishida, Yuho Furuki, Eiji Shibahashi, Kensuke Shimazaki, Haruki Sekiguchi, Yuichiro Minami, Junichi Yamaguchi, Hiroshi Ogawa, Nobuhisa Hagiwara ········· 1919 Preventive Medicine (3) 151. Empagliflozin and Cardiovascular Outcomes in Asian Patients With Type 2 Diabetes and Established Cardiovascular Disease ― Results From EMPA-REG OUTCOME® ― Kohei Kaku, Jisoo Lee, Michaela Mattheus, Stefan Kaspers, Jyothis George, Hans-Juergen Woerle on behalf of the EMPA-REG OUTCOME® Investigators ········· 227 152. Chromium Exposure and Risk of Cardiovascular Disease in High Cardiovascular Risk Subjects ― Nested Case- Control Study in the Prevention With Mediterranean Diet (PREDIMED) Study ― Mario Gutiérrez-Bedmar, Miguel Ángel Martínez-González, Carlos Muñoz-Bravo, Miguel Ruiz-Canela, Alberto Mariscal, Jordi Salas-Salvadó, Ramón Estruch, Dolores Corella, Fernando Arós, Monserrat Fito, José Lapetra, Lluís Serra-Majem, Xavier Pintó, Ángel Alonso-Gómez, Olga Portoles, Miquel Fiol, Mónica Bulló, Olga Castañer, Emilio Ros, Enrique Gómez-Gracia ········· 1183 153. Cross-Over Trial of Febuxostat and Topiroxostat for Hyperuricemia With Cardiovascular Disease (TROFEO Trial) Akira Sezai, Kazuaki Obata, Keisuke Abe, Sakie Kanno, Hisakuni Sekino ········· 1707 Pulmonary Circulation (3) 154. Reverse Right Ventricular Remodeling After Lung Transplantation in Patients With Pulmonary Arterial Hypertension Under Combination Therapy of Targeted Medical Drugs Toshihiro Sarashina, Kazufumi Nakamura, Satoshi Akagi, Takahiro Oto, Hiroki Oe, Kentaro Ejiri, Koji Nakagawa, Nobuhiro Nishii, Hiromi Matsubara, Motomu Kobayashi, Hiroshi Morimatsu, Shinichiro Miyoshi, Hiroshi Ito ········· 383 155. Improvement in Quality of Life and Hemodynamics in Chronic Thromboembolic Pulmonary Hypertension Treated With Balloon Pulmonary Angioplasty Szymon Darocha, Radosław Pietura, Arkadiusz Pietrasik, Justyna Norwa, Anna Dobosiewicz, Michał Piłka, Michał Florczyk, Andrzej Biederman, Adam Torbicki, Marcin Kurzyna ········· 552 156. Efficacy and Safety of an Orally Administered Selective Prostacyclin Receptor Agonist, Selexipag, in Japanese Patients With Pulmonary Arterial Hypertension Nobuhiro Tanabe, Satoshi Ikeda, Nobuhiro Tahara, Keiichi Fukuda, Masaru Hatano, Hiroshi Ito, Tomotaka Nakayama, Toshihisa Anzai, Akiyoshi Hashimoto, Teruo Inoue, Kouji Kajinami, Yasuki Kihara, Hideyuki Kinoshita, Koichiro Kuwahara, Toyoaki Murohara, Osamu Okazaki, Satoshi Sakai, Toru Satoh, Yutaka Takeda, Yasuchika Takeishi, Mitsugu Taniguchi, Hiroshi Watanabe, Takeshi Yamamoto, Keiko Yamauchi-Takihara, Koichiro Yoshioka, Shigetake Sasayama ········· 1360
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Regenerative Medicine (1) 157. Autologous Bone Marrow Mononuclear Cell Implantation and Its Impact on the Outcome of Patients With Critical Limb Ischemia ― Results of a Randomized, Double-Blind, Placebo-Controlled Trial ― Bernard Pignon, Marie-Antoinette Sevestre, Lukshe Kanagaratnam, Gilles Pernod, Dominique Stephan, Joseph Emmerich, Claude Clement, Gabrielle Sarlon, Carine Boulon, Claire Tournois, Philippe Nguyen ········· 1713 Renal Disease (3) 158. Sodium Bicarbonate-Ascorbic Acid Combination for Prevention of Contrast-Induced Nephropathy in Chronic Kidney Disease Patients Undergoing Catheterization Kota Komiyama, Takashi Ashikaga, Dai Inagaki, Tomonori Miyabe, Marina Arai, Kiyotaka Yoshida, Satoshi Miyazawa, Akihiro Nakada, Iwanari Kawamura, Shinichiro Masuda, Sho Nagamine, Rintaro Hojo, Yuya Aoyama, Takaaki Tsuchiyama, Seiji Fukamizu, Takashi Shibui, Harumizu Sakurada ········· 235 159. Impact of Acute Kidney Injury on In-Hospital Outcomes of Patients With Acute Myocardial Infarction ― Results From the Japanese Registry of Acute Myocardial Infarction Diagnosed by Universal Definition (J-MINUET) Substudy ― Shotaro Kuji, Masami Kosuge, Kazuo Kimura, Koichi Nakao, Yukio Ozaki, Junya Ako, Teruo Noguchi, Satoshi Yasuda, Satoru Suwa, Kazuteru Fujimoto, Yasuharu Nakama, Takashi Morita, Wataru Shimizu, Yoshihiko Saito, Atsushi Hirohata, Yasuhiro Morita, Teruo Inoue, Kunihiro Nishimura, Yoshihiro Miyamoto, Masaharu Ishihara on behalf of J-MINUET Investigators ········· 733 160. Tolvaptan Reduces the Risk of Worsening Renal Function in Patients With Acute Decompensated Heart Failure and Preserved Left Ventricular Ejection Fraction ― Prospective Randomized Controlled Study ― Shunsuke Tamaki, Yoshihiro Sato, Takahisa Yamada, Takashi Morita, Yoshio Furukawa, Yusuke Iwasaki, Masato Kawasaki, Atsushi Kikuchi, Takumi Kondo, Tatsuhisa Ozaki, Masahiro Seo, Iyo Ikeda, Eiji Fukuhara, Makoto Abe, Jun Nakamura, Masatake Fukunami ········· 740 Stroke (2) 161. Relationship Between Infarct Volume and Prothrombin Time-International Normalized Ratio in Ischemic Stroke Patients With Nonvalvular Atrial Fibrillation Mari Matsumoto, Manabu Sakaguchi, Shuhei Okazaki, Kazuo Hashikawa, Tsutomu Takahashi, Masayasu Matsumoto, Toshiho Ohtsuki, Takeshi Shimazu, Toshiki Yoshimine, Hideki Mochizuki, Kazuo Kitagawa ········· 391 162. Association of Kidney Dysfunction With Asymptomatic Cerebrovascular Abnormalities in a Japanese Population With Health Checkups Kaori Hayashi, Michiyo Takayama, Takeshi Kanda, Kazuhiro Kashiwagi, Akihito Hishikawa, Yasushi Iwao, Hiroshi Itoh ········· 1191 Valvular Heart Disease (12) 163. Favorable Clinical Outcomes of Transcatheter Aortic Valve Implantation in Japanese Patients ― First Report From the Post-Approval K-TAVI Registry ― Shinya Takimoto, Naritatsu Saito, Kenji Minakata, Shinichi Shirai, Akihiro Isotani, Yoshio Arai, Michiya Hanyu, Tatsuhiko Komiya, Takeshi Shimamoto, Tsuyoshi Goto, Yasushi Fuku, Natsuhiko Ehara, Yutaka Furukawa, Tadaaki Koyama, Atsuhi Nagasawa, Toshihiro Tamura, Makoto Miyake, Kazuo Yamanaka, Hisashi Sakaguchi, Koichiro Murata, Tomoya Onodera, Fumio Yamazaki, Masanao Nakai, Tomohiko Taniguchi, Ryuzo Sakata, Takeshi Kimura ········· 103 164. Clinical Outcomes and Bioprosthetic Valve Function After Transcatheter Aortic Valve Implantation Under Dual Antiplatelet Therapy vs. Aspirin Alone Yasuhiro Ichibori, Isamu Mizote, Koichi Maeda, Toshinari Onishi, Tomohito Ohtani, Osamu Yamaguchi, Kei Torikai, Toru Kuratani, Yoshiki Sawa, Satoshi Nakatani, Yasushi Sakata ········· 397 165. Impact of Mitral Annular Displacement on Left Ventricular Diastolic Function Improvement After Transcatheter Aortic Valve Implantation Hiroto Utsunomiya, Hirotsugu Mihara, Yuji Itabashi, Robert J. Siegel, Tarun Chakravarty, Hasan Jilaihawi, Raj R. Makkar, Takahiro Shiota ········· 558 166. Safety and Efficacy of Simultaneous Biplane Mode of 3-Dimensional Transesophageal Echocardiography-Guided Antegrade Multiple-Inflation Balloon Aortic Valvuloplasty in Patients With Severe Aortic Stenosis Kazuki Mizutani, Masahiko Hara, Hirotoshi Ishikawa, Shinsuke Nishimura, Asahiro Ito, Shinichi Iwata, Yosuke Takahashi, Kenichi Sugioka, Takashi Murakami, Toshihiko Shibata, Minoru Yoshiyama ········· 748 167. Transcatheter Aortic Valve Replacement With Different Valve Types in Elliptic Aortic Annuli Yoshio Maeno, Yigal Abramowitz, Sung-Han Yoon, Hasan Jilaihawi, Sharma Raul, Sharjeel Israr, Masaki Miyasaka, Hiroyuki Kawamori, Yoshio Kazuno, Tanya Rami, Nobuyuki Takahashi, Geeteshwar Mangat, Mohammad Kashif, Tarun Chakravarty, Mamoo Nakamura, Wen Cheng, Raj R. Makkar ········· 1036 168. Stenotic Bicuspid and Tricuspid Aortic Valves ― Micro-Computed Tomography and Biological Indices of Calcification ― Piotr Mazur, Ewa Wypasek, Bogusław Gawęda, Dorota Sobczyk, Przemysław Kapusta, Joanna Natorska, Krzysztof Piotr Malinowski, Jacek Tarasiuk, Maciej Bochenek, Sebastian Wroński, Katarzyna Chmielewska, Bogusław Kapelak, Anetta Undas ········· 1043
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169. Comparison of the Long-Term Outcomes of Mechanical and Bioprosthetic Aortic Valves ― A Propensity Score Analysis ― Kenji Minakata, Shiro Tanaka, Nobushige Tamura, Shigeki Yanagi, Yohei Ohkawa, Shuichi Okonogi, Tatsuo Kaneko, Akihiko Usui, Tomonobu Abe, Mitsuomi Shimamoto, Yoshiharu Takahara, Kazuo Yamanaka, Hitoshi Yaku, Ryuzo Sakata ········· 1198 170. Rate of Stenotic Bicuspid Aortic Valve Aortic Dilatation After Aortic Valve Replacement, Calculated Using a 3-Dimensional Reconstruction Tool Kaoru Hattori, Ikuo Fukuda, Kazuyuki Daitoku, Masahito Minakawa, Hiroyuki Itaya ········· 1207 171. Sex Differences in Severe Aortic Stenosis ― Clinical Presentation and Mortality ― Mamoru Toyofuku, Tomohiko Taniguchi, Takeshi Morimoto, Kyohei Yamaji, Yutaka Furukawa, Kosuke Takahashi, Takashi Tamura, Hiroki Shiomi, Kenji Ando, Norio Kanamori, Koichiro Murata, Takeshi Kitai, Yuichi Kawase, Chisato Izumi, Makoto Miyake, Hirokazu Mitsuoka, Masashi Kato, Yutaka Hirano, Shintaro Matsuda, Tsukasa Inada, Tomoyuki Murakami, Yasuyo Takeuchi, Keiichiro Yamane, Mitsuru Ishii, Eri Minamino-Muta, Takao Kato, Moriaki Inoko, Tomoyuki Ikeda, Akihiro Komasa, Katsuhisa Ishii, Kozo Hotta, Nobuya Higashitani, Yoshihiro Kato, Yasutaka Inuzuka, Chiyo Maeda, Toshikazu Jinnai, Yuko Morikami, Naritatsu Saito, Kenji Minatoya, Takeshi Kimura on behalf of the CURRENT AS Registry Investigators ········· 1213 172. Recent Surgical Results for Active Endocarditis Complicated With Perivalvular Abscess Daisuke Yoshioka, Koichi Toda, Jun-ya Yokoyama, Ryohei Matsuura, Shigeru Miyagawa, Yukitoshi Shirakawa, Toshiki Takahashi, Taichi Sakaguchi, Hirotsugu Fukuda, Yoshiki Sawa ········· 1721 173. Prolapse Volume to Prolapse Height Ratio for Differentiating Barlow’s Disease From Fibroelastic Deficiency Nobuyuki Kagiyama, Misako Toki, Akihiro Hayashida, Minako Ohara, Atsushi Hirohata, Keizo Yamamoto, Toshinori Totsugawa, Taichi Sakaguchi, Kiyoshi Yoshida, Mitsuaki Isobe ········· 1730 174. Significant Prognostic Value of Acute Preload Stress Echocardiography Using Leg-Positive Pressure Maneuver for Patients With Symptomatic Severe Aortic Stenosis Awaiting Aortic Valve Intervention Hiroki Matsuzoe, Kensuke Matsumoto, Hidekazu Tanaka, Yutaka Hatani, Keiko Hatazawa, Hiroyuki Shimoura, Junichi Ooka, Hiroyuki Sano, Keiko Ryo-Koriyama, Toshiro Shinke, Hirotsugu Yamada, Yutaka Okita, Ken-ichi Hirata ········· 1927 Vascular Biology and Vascular Medicine (9) 175. Transcriptional Analysis of Intravenous Immunoglobulin Resistance in Kawasaki Disease Using an Induced Pluripotent Stem Cell Disease Model Kazuyuki Ikeda, Yasutaka Mizoro, Tomonaga Ameku, Yui Nomiya, Shin-Ichi Mae, Satoshi Matsui, Yuki Kuchitsu, Chinatsu Suzuki, Akiko Hamaoka-Okamoto, Tomoyo Yahata, Masakatsu Sone, Keisuke Okita, Akira Watanabe, Kenji Osafune, Kenji Hamaoka ········· 110 176. Differences in Cardiovascular Responses to Alamandine in Two-Kidney, One Clip Hypertensive and Normotensive Rats Ava Soltani Hekmat, Kazem Javanmardi, Amin Kouhpayeh, Ehsan Baharamali, Mojtaba Farjam ········· 405 177. Effect of MicroRNA-30e on the Behavior of Vascular Smooth Muscle Cells via Targeting Ubiquitin-Conjugating Enzyme E2I Yu Zong, Pei Wu, Changsheng Nai, Yuanyuan Luo, Fengwang Hu, Wen Gao, Nana Zhai, Tongda Xu, Dongye Li ········· 567 178. Diallyl Trisulfide Augments Ischemia-Induced Angiogenesis via an Endothelial Nitric Oxide Synthase-Dependent Mechanism Ryo Hayashida, Kazuhisa Kondo, Sumio Morita, Kazumasa Unno, Satoshi Shintani, Yuuki Shimizu, John W. Calvert, Rei Shibata, Toyoaki Murohara ········· 870 179. Cerebral Hemodynamics and Metabolism During Cardiac Arrest and Cardiopulmonary Resuscitation Using Hyperspectral Near Infrared Spectroscopy Reyhaneh Nosrati, Steve Lin, Andrew Ramadeen, Dena Monjazebi, Paul Dorian, Vladislav Toronov ········· 879 180. Enhancement of Nitric Oxide Production Is Responsible for Minimal Intimal Hyperplasia of Autogenous Rabbit Arterial Grafts Koki Tabata, Kimihiro Komori, Ryo Otsuka, Junko Kajikuri, Takeo Itoh ········· 1222 181. Cytokine Response to Diet and Exercise Affects Atheromatous Matrix Metalloproteinase-2/9 Activity in Mice Soo-Min Shon, Hee Jeong Jang, Dawid Schellingerhout, Jeong-Yeon Kim, Wi-Sun Ryu, Su-Kyoung Lee, Jiwon Kim, Jin-Yong Park, Ji Hye Oh, Jeong Wook Kang, Kang-Hoon Je, Jung E Park, Kwangmeyung Kim, Ick Chan Kwon, Juneyoung Lee, Matthias Nahrendorf, Jong-Ho Park, Dong-Eog Kim ········· 1528 182. Asymptomatic Lower Extremity Deep Vein Thrombosis ― Clinical Characteristics, Management Strategies, and Long-Term Outcomes ― Yugo Yamashita, Hiroki Shiomi, Takeshi Morimoto, Tomoya Yoneda, Chinatsu Yamada, Takeru Makiyama, Takao Kato, Naritatsu Saito, Satoshi Shizuta, Koh Ono, Takeshi Kimura ········· 1936 183. Increased Carotid Artery Lesion Inflammation Upon Treatment With the CD137 Agonistic Antibody 2A Leif Å. Söderström, Hong Jin, April S. Caravaca, Maria L. Klement, Yuhuang Li, Anton Gisterå, Ulf Hedin, Lars Maegdefessel, Göran K. Hansson, Peder S. Olofsson ········· 1945
Circulation Journal Vol.81, December 2017 xviii Contents of Volume 81, 2017
Rapid Communications
1. Fluctuation of Dynamic Diastolic Function Relative to Static Cardiac Structure ― New Insights Into the Underlying Mechanism of Heart Failure With Preserved Ejection Fraction in Elderly Patients ― Shiro Hoshida, Yukinori Shinoda, Kuniyasu Ikeoka, Tomoko Minamisaka, Hidetada Fukuoka, Hirooki Inui, Tetsuya Watanabe ········· 755 2. Relaxin and Matrix Metalloproteinase-9 in Angiotensin II-Induced Abdominal Aortic Aneurysms Deborah A. Howatt, Maya Dajee, Xiaojie Xie, Jessica Moorleghen, Debra L. Rateri, Anju Balakrishnan, Valdeci Da Cunha, Douglas G. Johns, David E. Gutstein, Alan Daugherty, Hong Lu ········· 888 3. Depressive Status in Patients With Chronic Thromboembolic Pulmonary Hypertension Sayaka Funabashi, Masaharu Kataoka, Takumi Inami, Toshiaki Kikuchi, Ryoji Yanagisawa, Chikako Ishiguro, Susumu Okamoto, Hideaki Yoshino, Koichiro Watanabe, Toru Satoh ········· 1051 4. Trend in the Prevalence of Atrial Fibrillation During the Past 15 Years in Iwate (Northeastern Area of Japan) Kenji Tamaki, Makoto Koshiyama, Masaki Ohsawa ········· 1537 5. Proposed Cutoff Value of Brachial-Ankle Pulse Wave Velocity for the Management of Hypertension Toshiaki Ohkuma, Hirofumi Tomiyama, Toshiharu Ninomiya, Kazuomi Kario, Satoshi Hoshide, Yoshikuni Kita, Toyoshi Inoguchi, Yasutaka Maeda, Katsuhiko Kohara, Yasuharu Tabara, Motoyuki Nakamura, Takayoshi Ohkubo, Hirotaka Watada, Masanori Munakata, Mitsuru Ohishi, Norihisa Ito, Michinari Nakamura, Tetsuo Shoji, Charalambos Vlachopoulos, Akira Yamashina on behalf of the Collaborative Group for Japan Brachial-Ankle pulse wave VELocity individual participant data meta-analysis of prospective studies (J-BAVEL) ········· 1540 6. Galectin-3 and the Mineralocorticoid Receptor Antagonist Canrenone in Mild Heart Failure Francesco Clemenza, Serge Masson, Pier Giulio Conaldi, Daniele Di Carlo, Alessandro Boccanelli, Gian Francesco Mureddu, Lucio Gonzini, Donata Lucci, Aldo P. Maggioni, Andrea Di Lenarda, Enrico B. Nicolis, Massimo Vanasia, Roberto Latini on behalf of the AREA IN-CHF Investigators ········· 1543 7. Safety and Efficacy of Long-Term Use of Tolvaptan in Patients With Heart Failure and Chronic Kidney Disease Yusuke Uemura, Rei Shibata, Kenji Takemoto, Tomohiro Uchikawa, Masayoshi Koyasu, Shinji Ishikawa, Ryo Imai, Yuta Ozaki, Takashi Watanabe, Tsubasa Teraoka, Masato Watarai, Toyoaki Murohara ········· 1736 8. Trends in Hospitalizations for Cardiac Sarcoidosis in the United States, 2005–2011 Xiaofan Guo, Eric Vittinghoff, Vasanth Vedantham, Mark J. Pletcher, Byron K. Lee ········· 1739
Images in Cardiovascular Medicine
1. Lethal Cement Leakage Embolization After Kyphoplasty Jin-Sun Park, Joon-Han Shin, Sang-Hyun Lim, Hyoung-Mo Yang ········· 119 2. 18F-Fluorodeoxyglucose Positron Emission Tomography for the Diagnosis of Myocarditis Associated With Polymyositis Tatsuya Shigematsu, Hideki Okayama, Go Hiasa, Yukio Kazatani ········· 121 3. Acute Aortic Valve Regurgitation Due to Spontaneous Rupture of Fenestrated Cusp Treated With Aortic Valve Repair Keitaro Mahara, Mitsuhiko Ota, Kanako Kishiki, Shuichiro Takanashi ········· 241 4. Improvement in Microvascular Ischemia After Enzyme Replacement Therapy in Anderson-Fabry Disease ― Computed Tomography Myocardial Perfusion Imaging ― Hideaki Yuki, Daisuke Utsunomiya, Yasuhiro Izumiya, Seitaro Oda, Masafumi Kidoh, Seiji Takashio, Megumi Yamamuro, Seiji Hokimoto, Yasuyuki Yamashita ········· 243 5. Multi-Modality Imaging of Drug-Eluting Stent-Related Multi-Vessel Coronary Aneurysms Presenting as Recurrent Stent Thrombosis Gunasekaran Sengottuvelu, Ravindran Rajendran, Immaneni Sathyamurthy ········· 413 6. Giant Right Atrial Aneurysm ― Multimodality Imaging ― Jong-Ho Nam, Chan-Hee Lee ········· 415 7. Unusual Case of Rupture of Right Sinus of Valsalva Aneurysm Into the Left Ventricle Kiyoshi Masuyama, Hitoshi Nakamura, Naotaka Okamoto, Akihiro Tanaka, Naoki Mori, Daisuke Nakamura, Masamichi Yano, Nobuhiko Makino, Yasuyuki Egami, Ryu Shutta, Jun Tanouchi, Masami Nishino ········· 577 8. Stent Recoil Manifesting as Early Stent Thrombosis After Ultimaster Thin-Strut, Cobalt-Chromium Sirolimus- Eluting Stent Implantation Akira Sato, Masafumi Ohtani, Hiroaki Watabe, Daiki Akiyama, Tomoya Hoshi, Kazutaka Aonuma ········· 579 9. Ventricular Fibrillation Triggered by Earthquake During the Accumoli-Amatrice Disaster in Italy Mauro Biffi, Andrea Candelora, Giulia Massaro ········· 759 10. Successful Stent-Retriever Thrombectomy for Acute Cerebral Embolization After Transcatheter Aortic Valve Implantation Mizuki Miura, Shinichi Shirai, Katsumi Inoue, Masaomi Hayashi, Shinichi Kakumoto, Katsuhiro Seo, Yoshio Arai, Michiya Hanyu, Kenji Ando ········· 761
Circulation Journal Vol.81, December 2017 Contents of Volume 81, 2017 xix
11. Unexpected Electrical Isolation of the Superior Vena Cava During Radiofrequency Hot Balloon Ablation in the Right Superior Pulmonary Vein Hiro Yamasaki, Toru Adachi, Yuki Komatsu, Kenji Kuroki, Yukio Sekiguchi, Akihiko Nogami, Kazutaka Aonuma ········· 763 12. Neoatherosclerosis in the Iliac Artery Stent ― Insights From Optical Coherence Tomography and Intravascular Ultrasound ― Takeshi Yagyu, Osami Kawarada, Fumiyuki Otsuka, Teruo Noguchi, Satoshi Yasuda ········· 891 13. Cardiac Amyloidosis Associated With Amyloidogenic Transthyretin V122I Variant in an Elderly Japanese Woman Tsuneaki Yoshinaga, Masahide Yazaki, Masakazu Ohno, Satoshi Kodama, Jun Koyama, Yoshiki Sekijima ········· 893 14. Eccentric Left Ventricular Hypertrophy in Aortic Stenosis Caused by Unicuspid Aortic Valve Haruhiko Higashi, Akiyoshi Ogimoto, Katsuji Inoue, Naohito Tokunaga, Chiharuko Iio, Jun Aono, Satoshi Yoshida, Hironori Izutani, Yasuharu Tabara, Takafumi Okura, Jitsuo Higaki, Shuntaro Ikeda ········· 895 15. Localized Inflammation and Aneurysm Formation 10 Years After Sirolimus-Eluting Stent Implantation Takeru Nabeta, Takehiro Hashikata, Taiki Tojo, Ryota Kakizaki, Yoshiyasu Minami, Kentaro Meguro, Takao Shimohama, Shigeru Suzuki, Yusuke Inoue, Junya Ako ········· 1054 16. Uncommon Isolated Unilocular Myocardial Cyst in a Dog-Friendly Young Female Patient ― Multimodality Imaging ― Cesare Mantini, Carlo Capparuccia, Filippo Cademartiri, Giancarlo Messalli, Domenico Mastrodicasa, Sebastiano Cinalli, Antonio Raffaele Cotroneo, Marcello Caputo ········· 1056 17. Four-Dimensional Computed Tomography-Based Finite Element Modeling of the Behavior of the Right Coronary Artery Yoshihisa Nakagawa, Hidetaka Hayashi, Chisato Izumi, Hirokazu Kondo, Toshihiro Tamura, Soichiro Enomoto, Masashi Amano, Shunsuke Nishimura, Yuko Tanaka, Tomoharu Isshiki, Hiroshi Watanabe, Kanji Hanafusa, Yuichi Yamazaki, Tomohiro Nakamura, Kazunori Eguchi ········· 1059 18. Sequential Acute Coronary Syndrome 4 Days Apart: A Missed Opportunity? Iwao Okai, Hiroshi Iwata, Eric A. Osborn, Kentaro Fukuda, Masayuki Shiozaki, Yuki Kimura, Yuichi Chikata, Kenji Inoue, Yasumasa Fujiwara, Farouc A. Jaffer, Hiroyuki Daida, Masataka Sumiyoshi ········· 1231 19. Lotus Root Sign in the Renal Artery in Renovascular Hypertension Kazuhiko Nakazato, Atsushi Kobayashi, Minoru Nodera, Masashi Kamioka, Hitoshi Suzuki, Shu-ichi Saitoh, Yasuchika Takeishi ········· 1234 20. Silent Progression of Coronary Artery Thrombosis in a Pregnant Woman With Anomalous Origin of Left Coronary Artery From the Pulmonary Artery Kenichiro Yamamura, Ichiro Sakamoto, Yuzo Yamasaki, Arisa Fujiwara, Michinobu Nagao, Hidetoshi Takada ········· 1236 21. Myocardial Edema in Takotsubo Syndrome ― Serial Cardiovascular Magnetic Resonance Imaging of the Natural Course ― Ken Kato, Michiko Daimon, Iwao Ishibashi, Yoshio Kobayashi ········· 1368 22. Atrial Septum Hematoma ― Another Way to Die in Acute Aortic Dissection ― Juan Carlos Gómez-Polo, Isidre Vilacosta, Estela Aguilar-Navarro, Carlos Ferrera, Sandra Rosillo, Guillermo García-Diego, Carmen Olmos, Pedro Martínez-Losas, David Vivas, Francisco J. Noriega-Sanz, Ana Viana-Tejedor, Luis Ortega ········· 1370 23. Infective Endocarditis of a Completely Endothelialized CardioSEAL Patent Foramen Ovale Closure Device ― Extremely Rare Entity ― Gaurav K. Sharma, Quratulain A. Samoon, Taimur Abbasi, Angie Tripathi, Amit Kumar, Conner O’Keefe, Arijit Dasgupta, Robert Gasior, Paul A. Jones ········· 1373 24. Adult Partial Anomalous Pulmonary Venous Connection With Drainage to Left Atrium and Inferior Vena Cava Clearly Visualized on a Combination of Multiple Imaging Techniques Hajime Kasai, Toshihiko Sugiura, Takahiro Arano, Hiroki Shoji, Takayuki Jujo, Seiichiro Sakao, Nobuhiro Tanabe, Koichiro Tatsumi ········· 1547 25. Congenital Ostial Atresia of the Left Anterior Descending Artery Yumi Ishii, Kunio Yufu, Tetsuji Shinohara, Hidekazu Kondo, Akira Fukui, Norihiro Okada, Hidefumi Akioka, Yasushi Teshima, Mikiko Nakagawa, Taiki Nishihara, Eisaku Okuyama, Keisuke Watanabe, Koichi Kikuta, Naohiko Takahashi ········· 1550 26. Intracardiac Echocardiography-Guided Biopsy of a Lipomatous Cardiac Tumor Arising From the Interatrial Septum Akira Takashima, Tatsuro Ogata, Hirotsugu Yamada, Tetsuzo Wakatsuki, Masataka Sata ········· 1553 27. Macrophage Infiltration Into the Endothelium of Atrial Tissue in Atrial Fibrillation Yuko Sonoda, Yasushi Teshima, Ichitaro Abe, Yuki Ebata, Takahiro Oniki, Shintaro Kira, Hidekazu Kondo, Shotaro Saito, Kunio Yufu, Shinji Miyamoto, Tatsuo Shimada, Naohiko Takahashi ········· 1742 28. Aortopathy in an Adult With Tricuspid Atresia and Left Ventricular Non-Compaction After Fontan Procedure Tomotaka Murakami, Yoshiki Mori, Nao Inoue, Sachie Kaneko, Yasumi Nakashima ········· 1745 29. High Signal Intensity in Arterial Walls on Diffusion-Weighted Magnetic Resonance Imaging in the Active Phase of Takayasu Arteritis Yasuyoshi Kuroiwa, Hiroshi Tai, Atsushi Yamashita, Eiji Furukoji, Yasushi Kihara, Toshinori Hirai, Yujiro Asada, Takuroh Imamura ········· 1747
Circulation Journal Vol.81, December 2017 xx Contents of Volume 81, 2017
30. Different Calcification Stage in Each Cusp of a Calcified Tricuspid Aortic Valve Ching-Li Cheng, Hsiao-Huang Chang, Pei-Jung Huang, Wei-Chen Wang, Shan-Yang Lin ········· 1953 31. Iatrogenic Injury of Right Coronary Artery During Tricuspid Annuloplasty Satoshi Kainuma, Hiroya Yamamoto, Shohei Yamada, Yu Yamada, Akinori Sumiyoshi, Atsunori Okamura, Katsuomi Iwakura, Yuka Miyata, Yukio Hayashi, Masakazu Ueda, Yoshiki Sawa, Takafumi Masai ········· 1956 32. Pulmonary Tumor Thrombotic Microangiopathy ― Antemortem Diagnosis With Pulmonary Artery Wedge Blood Cell Sampling in a Recurrent Breast Cancer Patient ― Shunichiro Fuchigami, Ryusuke Tsunoda, Hiroshi Shimizu, Masafumi Takae, Hiroki Usuku, Hiromi Yoshimura, Tomokazu Ikemoto, Michiko Nagamine, Teruhiko Ito, Yasuhiro Izumiya, Koichi Kaikita, Seiji Hokimoto, Kenichi Tsujita ········· 1959
JCS Guidelines
1. Guidelines for Perioperative Cardiovascular Evaluation and Management for Noncardiac Surgery (JCS 2014) ― Digest Version ― Shunei Kyo, Kazuhito Imanaka, Munetaka Masuda, Tetsuro Miyata, Kiyozo Morita, Tetsuro Morota, Minoru Nomura, Yoshikatsu Saiki, Yoshiki Sawa, Taijiro Sueda, Yuichi Ueda, Kenji Yamazaki, Ryohei Yozu, Mari Iwamoto, Shunsuke Kawamoto, Isamu Koyama, Mikihiko Kudo, Goro Matsumiya, Kazumasa Orihashi, Hideki Oshima, Satoshi Saito, Yoshimasa Sakamoto, Kunihiro Shigematsu, Tsuyoshi Taketani, Issei Komuro, Shinichi Takamoto, Chuwa Tei, Fumio Yamamoto on behalf of the Japanese Circulation Society Joint Working Group ········· 245 2. Guidelines for Therapeutic Drug Monitoring of Cardiovascular Drugs Clinical Use of Blood Drug Concentration Monitoring (JCS 2015) ― Digest Version ― Kazutaka Aonuma (JCS), Tsuyoshi Shiga (JSTDM), Hirotsugu Atarashi, Kosuke Doki, Hirotoshi Echizen, Nobuhisa Hagiwara, Junichi Hasegawa, Hideharu Hayashi, Kenzo Hirao, Fukiko Ichida, Takanori Ikeda, Yorinobu Maeda, Naoki Matsumoto, Toshiyuki Sakaeda, Wataru Shimizu, Mitsuru Sugawara, Kyoichi Totsuka, Yoshimasa Tsuchishita, Kazuyuki Ueno, Eiichi Watanabe, Masayuki Hashiguchi, Sumio Hirata, Hidefumi Kasai, Yoshiaki Matsumoto, Akihiko Nogami, Yukio Sekiguchi, Tokuko Shinohara, Atsushi Sugiyama, Naokata Sumitomo, Atsushi Suzuki, Naohiko Takahashi, Eiji Yukawa, Masato Homma, Minoru Horie, Hiroshi Inoue, Hiroshi Ito, Takanori Miura, Tohru Ohe, Kimikazu Shinozaki, Kazuhiko Tanaka on behalf of the Japanese Circulation Society and the Japanese Society of Therapeutic Drug Monitoring Joint Working Group ········· 581
Letters to the Editor
1. Cancer and Takotsubo Syndrome: a Need to Explore a Very Complex Association (Letter) John E. Madias ········· 123 (Reply) Olivier Morel, Nathan Messas, Alessio Imperiale, Cyrille Blondet, Laurence Jesel ········· 124 2. Insomnia and Cardiac Events in Patients With Heart Failure (Letter) Tomoyuki Kawada ········· 125 (Reply) Akiomi Yoshihisa, Yuki Kanno, Yasuchika Takeishi ········· 126 3. Increased Coagulation With Aging: Importance of Homocysteine and Vitamin B12 (Letter) J. David Spence ········· 268 (Reply) Akinori Ochi, Taro Adachi, Youichi Kobayashi ········· 269 4. Nocardia Identification at the Genus Level (Letter) Mehdi Fatahi-Bafghi ········· 270 (Reply) Akira Takashima, Shusuke Yagi, Hiroyuki Ito, Masataka Sata ········· 271 5. Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitors and Stroke (Letter) Genjiro Kimura ········· 898 (Reply) Kohei Kaku, Jisoo Lee, Stefan Kaspers, Hans J. Woerle, Jyothis T. George ········· 899 6. Survival in Young Patients With Noncompaction May Not Only Depend on Cardiac But Also on Neuromuscular Comorbidity (Letter) Claudia Stöllberger, Josef Finsterer ········· 1238 (Reply) Ce Wang, Xianyi Yu, Fukiko Ichida ········· 1239 7. Exercise Transcutaneous Oximetry of the Buttocks, External Validation With Computed Tomography Angiography (Letter) Loukman Omarjee, Olivier Stivalet, Guillaume Mahe, Vincent Jaquinandi ········· 1375
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