DOCSLIB.ORG

Wastewater Surveillance of the COVID-19 Genetic Signal in Sewersheds Recommendations from Global Experts

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Wastewater Surveillance of the COVID-19 Genetic Signal in Sewersheds Recommendations from Global Experts Wastewater Surveillance of the COVID-19 Genetic Signal in Sewersheds Recommendations from Global Experts The Water Research Foundation convened the International Water Research Summit on Environmental Surveillance of COVID-19 Indicators in Sewersheds in response to the overwhelming need for information regarding the distribution and prevalence of COVID-19. The global water sector has mobilized to investigate the use of wastewater surveillance of the genetic signal of SARS CoV-2 as an indicator of the distribution of COVID-19 in communities. This paper presents recommendations of global experts who contributed to the Summit, including potential uses of wastewater surveillance for tracking COVID-19, sampling design, analytical tools, and communication of results to public health decision makers, the public, and other key stakeholders. www.waterrf.org The Water Research Foundation (WRF) is a 501(c)(3) nonprofit organization that provides a unified source for One Water research and a strong presence in relationships with partner organizations, government and regulatory agencies, and Congress. WRF conducts research in all areas of drinking water, wastewater, stormwater, and water reuse. The Water Research Foundation’s research portfolio is valued at over $700 million. WRF plays an important role in the translation and dissemination of applied research, technology demonstration, and education, through creation of research-based educational tools and technology exchange opportunities. WRF serves as a leader and model for collaboration across the water industry, and its materials are used to inform policymakers and the public on the science, economic value, and environmental benefits of using and recovering resources found in water, as well as the feasibility of implementing new technologies. For more information, contact: The Water Research Foundation 1199 North Fairfax Street, Suite 900 6666 West Quincy Avenue Alexandria, VA 22314-1445 Denver, CO 80235-3098 P 571.384.2100 P 303.347.6100 www.waterrf.org [email protected] ©Copyright 2020 by The Water Research Foundation. All rights reserved. Permission to copy must be obtained from The Water Research Foundation. This report was prepared by The Water Research Foundation. Neither The Water Research Foundation, members of The Water Research Foundation, the organization(s) named within, nor any person acting on their behalf: (a) makes any warranty, express or implied, with respect to the use of any information, apparatus, method, or process disclosed in this report or that such use may not infringe on privately owned rights; or (b) assumes any liabilities with respect to the use of, or for damages resulting from the use of, any information, apparatus, method, or process disclosed in this report. This document was reviewed by a panel of independent experts selected by The Water Research Foundation. Mention of trade names or commercial products or services does not constitute endorsement or recommendations for use. Similarly, omission of products or trade names indicates nothing concerning The Water Research Foundation’s positions regarding product effectiveness or applicability. 2 Acknowledgments THE WATER RESEARCH FOUNDATION WOULD like to thank Working Group 3: the following professionals who generously volunteered their Co-chairs: Chuck Haas, Drexel University; Doug Yoder, time and expertise to the Summit. Miami-Dade Water and Sewer; Gertjan Medema, KWR Water Research Institute; Vanessa Speight, University of Sheffield; Working Group 1: John Albert, WRF Co-chairs: Chuck Gerba, University of Arizona; Jim Pletl, Participants: Mia Mattioli, CDC; Jay Garland, U.S. Hampton Roads Sanitation District; Daniel Gerrity, Southern Environmental Protection Agency (EPA); Jeff Soller, Soller Nevada Water Authority; Alice Fulmer, WRF Environmental LLC; John Norton, Great Lakes Water Participants: Mark Sobsey, University of North Carolina at Authority; Jeff Prevatt, Pima County Regional Wastewater Chapel Hill; Amy Pickering, Tufts University; Mark Jones, UK Reclamation Department; Dimitri Katehis, New York City Water Industry Research (UKWIR); Katrina Charles, Oxford Department of Environmental Protection; Steve Rhode, University; Kelly Hill, Water Research Australia; Christoph Massachusetts Water Resources Authority; Ken Williamson, Ort, Eawag – Swiss Federal Institute of Aquatic Science Clean Water Services; Paul Kadota, Metro Vancouver; Reynald and Technology; Matt Burd, New York City Department of Bonnard, Suez Environmental Research Center Environmental Protection; Kaylyn Patterson, Metropolitan Water Reclamation District of Greater Chicago; Scott Working Group 4: Meschke, University of Washington; Amy Kirby, Centers for Co-chairs: Jim McQuarrie, Metro Wastewater Reclamation Disease Control and Prevention (CDC) District; Cathy Bernardino Bailey, Greater Cincinnati Water Works; Dan Deere, Water Futures; Lexie Vean, WRF Working Group 2: Participants: Jeff Oxenford, Rural Community Assistance Co-chairs: Krista Wigginton, University of Michigan; Partnership; Vince Hill, CDC; Claire Waggoner, California State Frederic Been, KWR Water Research Institute; Joan Rose, Water Resources Control Board; Karen Mogus, California Michigan State University; Christobel Ferguson, WRF State Water Resources Control Board; Chris Impellitteri, Participants: Raul Gonzalez, Hampton Roads Sanitation EPA; Diane Taniguchi-Dennis, Clean Water Services; District; Kellogg Schwab, Johns Hopkins University; Scott Gabriella Rundblad, King’s College London; Josef Klinger, Meschke, University of Washington; Rosina Girones, University Technologiezentrum Wasser (TZW); Bruno Tisserand, Veolia; of Barcelona; Kaye Power, Sydney Water; Sudhi Payyappat, Stephanie Rinck-Pfeiffer, Global Water Research Coalition; Sydney Water; Zia Bukhari, American Water; Farida Bishay, Yvonne Forrest, Houston Water Metro Vancouver; Tiong Gim Aw, Tulane University 3 Table of Contents Acknowledgments ...................................................................................................................................................................... 3 Context ........................................................................................................................................................................................ 5 Summit Structure ....................................................................................................................................................................... 6 Recommended Use Cases for Environmental Surveillance of the Genetic Signal of SARS-CoV-2 in Sewersheds ....................... 7 Introduction ........................................................................................................................................................................... 7 How Can SARS-CoV-2 Wastewater Surveillance Data Be Used? ........................................................................................ 7 Use Cases .............................................................................................................................................................................. 7 What Else Can Wastewater Surveillance Be Used For? ....................................................................................................... 8 Communication of Wastewater Surveillance Results with the Public Health Community, Elected Officials, Wastewater Workers, and the Public ............................................................................................................................................................. 9 Guiding Principles for Effective Communication .................................................................................................................. 9 Roles and Responsibilities ...................................................................................................................................................10 Communication Tools ..........................................................................................................................................................10 Sample Plan Design, Sample Collection, and Preservation of Wastewater Samples ..............................................................12 Guiding Principles ................................................................................................................................................................12 Wastewater Surveillance Sample Plan Design: General Considerations ...........................................................................12 General Use Case: Trends/Changes in Occurrence .............................................................................................................15 General Use Case: Assessment of Community Prevalence ................................................................................................16 General Use Case: Risk Assessment for Wastewater Exposure .........................................................................................16 General Use Case: Viral Evolution .......................................................................................................................................16 Tools to Quantify the SARS-CoV-2 Genetic Signal in Wastewater Samples .............................................................................17 Introduction ..........................................................................................................................................................................17 Analysis Guiding
Load more

Recommended publications
  • Cov-2 Wastewater Surveillance System (Vatar COVID-19) from December 2020 to March
    medRxiv preprint doi: https://doi.org/10.1101/2021.05.27.21257918; this version posted May 30, 2021. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission. Monitoring emergence of SARS-CoV-2 B.1.1.7 Variant through the Spanish National SARS- CoV-2 Wastewater Surveillance System (VATar COVID-19) from December 2020 to March 2021 Albert Carcereny1, Adán Martínez-Velázquez1, Albert Bosch1, Ana Allende2, Pilar Truchado2, Jenifer Cascales2, Jesús L Romalde3, Marta Lois3, David Polo3, Gloria Sánchez4, Alba Pérez- Cataluña4, Azahara Díaz-Reolid4, Andrés Antón5, Josep Gregori6,7, Damir Garcia-Cehic6,7, Josep Quer6,7, Margarita Palau8, Cristina González Ruano9, Rosa M Pintó1#* and Susana Guix1#* 1 Enteric Virus laboratory, Department of Genetics, Microbiology and Statistics, Section of Microbiology, Virology and Biotechnology, School of Biology, and Institute of Nutrition and Food Safety (INSA), University of Barcelona, Barcelona, Spain. 2 Research Group on Microbiology and Quality of Fruit and Vegetables, CEBAS-CSIC, Campus Universitario de Espinardo, 25, 30100, Murcia, Spain. 3 Department of Microbiology and Parasitology, CIBUS-Faculty of Biology & Institute CRETUS, Universidade de Santiago de Compostela, Santiago de Compostela, 15782, Spain. 4 Department of Preservation and Food Safety Technologies, Institute of Agrochemistry and Food Technology, IATA-CSIC, Av. Agustín Escardino 7, Paterna, 46980, Valencia, Spain. 5 Microbiology Department, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain.
    [Show full text]
  • Standards to Support an Enduring Capability in Wastewater Surveillance for Public Health
    DHS/NIST Workshop: Standards to Support an Enduring Capability in Wastewater Surveillance for Public Health Poster Abstracts June 14-18th 2021 Virtual Poster Session https://swwsworkshop.virtualpostersession.org/ CEDAR-MC: Clinical and Environmental Dynamics of Antibiotic Resistance within Microbial Communities George Hanna1,2, Bashir Hamidi1, Scott Curry1, Cheryl Carmack2, Alexander V. Alekseyenko1 1Medical University of South Carolina; 2Charleston Waterkeeper Introduction: Escape into the environment and the persistence of antibiotic resistance is an imminent threat to the healthcare advances attained in the 20th century. Microbial communities that co-exist with resistant bacteria may help uncover novel strategies for global antimicrobial control and curb emergence and maintenance of resistance. However, availability of clinically relevant specimens with complementary samples from the built and natural environment is a major obstacle to effective studies of the dynamics of resistance in the affected human populations and in their surroundings. Methods: We bring together environmental and clinical measurements of the microbial communities with evidence for emerging resistance by linking existing local clinical and environmental surveillance programs. The clinical specimens are sourced from the Medical University of South Carolina (MUSC) infection surveillance culture program that routinely samples the MUSC patient population for clinically relevant pathogens. The environmental specimens are the result of partnership with a local non-profit,
    [Show full text]
  • Wastewater Based Epidemiology Perspective As a Faster Protocol for Detecting Coronavirus RNA in Human Populations: a Review with Specific Reference to SARS-Cov-2 Virus
    pathogens Review Wastewater Based Epidemiology Perspective as a Faster Protocol for Detecting Coronavirus RNA in Human Populations: A Review with Specific Reference to SARS-CoV-2 Virus Milad Mousazadeh 1,2,†,‡ , Razieh Ashoori 3, Biswaranjan Paital 4 , I¸sıkKabda¸slı 5,‡ , Zacharias Frontistis 6 , Marjan Hashemi 7 , Miguel A. Sandoval 8,9,‡ , Samendra Sherchan 10, Kabita Das 11 and Mohammad Mahdi Emamjomeh 12,* 1 Student Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran; [email protected] 2 Department of Environmental Health Engineering, School of Health, Qazvin University of Medical Sciences, Qazvin, Iran 3 Department of Environmental Health Engineering, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran; [email protected] 4 Redox Regulation Laboratory, College of Basic Science and Humanities, Odisha University of Agriculture and Technology, Bhubaneswar 751003, India; [email protected] 5 Environmental Engineering Department, Civil Engineering Faculty, Ayaza˘gaCampus, Istanbul˙ Technical University, Istanbul˙ 34469, Turkey; [email protected] 6 Department of Chemical Engineering, University of Western Macedonia, 50132 Kozani, Greece; Citation: Mousazadeh, M.; Ashoori, [email protected] 7 Environmental and Occupational Hazards Control Research Center, Shahid Beheshti University of Medical R.; Paital, B.; Kabda¸slı,I.; Frontistis, Sciences, Tehran, Iran; [email protected] Z.; Hashemi, M.; Sandoval, M.A.; 8 Laboratorio de Electroquímica Medio Ambiental LEQMA, Departamento
    [Show full text]
  • Wastewater Surveillance Collaborative MOU FINAL
    Colorado SARS-CoV-2 Wastewater Surveillance Collaborative Memorandum of Understanding July 2020 Section 1 Background The Colorado Department of Public Health and Environment (Department) is partnering with Colorado State University, Metropolitan State University of Denver (MSU), and 17 Wastewater Utilities to develop a statewide wastewater surveillance system of SARS-CoV-2 RNA, the etiological agent of COVID19. The purpose of the surveillance system is to provide early warning (days to a week) for state and local health authorities of significant changes in fecal shedding of SARS-CoV-2 that could be used in combination with other surveillance efforts and drive action in responding to future COVID19 outbreaks. This testing could also confirm downward trends in COVID-19 outbreaks. With more data and analysis, it may also be useful for predicting community prevalence or to identify potential virus hot spots. Section 2 Purpose This agreement is being entered into by the Memorandum of Understanding (MOU) parties so that roles and responsibilities of each member of the collaborative are understood. The Department has secured $520,000 in funding for this project and this MOU is focused on how those dollars will be leveraged. The effort is scalable and may be expanded through future agreements. The financial obligations under this MOU are contingent upon appropriation, budgeting, and availability of specific funds to discharge those obligations. Nothing in this MOU constitutes a debt, a direct or indirect multiple fiscal year financial obligation or a pledge of a Wastewater Utilities’ credit. Section 3 MOU Parties The following entities are parties to this MOU, individually referred to as Wastewater Utilities, Universities, and Regulatory Agencies.
    [Show full text]
  • Media Monitoring: Extract of Press News on Higher Education in Africa
    Issue 86 Media Monitoring: Extract of Press News on Higher Education in Africa 1. World Bank Increased Investment in Zimbabwe’s Tertiary Education Essential to Economic Growth, Human Capital Development (Zimbabwe) Extensive reforms are required to translate the government’s education vision into a concrete set of programs and projects to accelerate economic recovery and reduce socioeconomic disparities, the Zimbabwe Higher and Tertiary Education Sector Analysis Report found. Developed by the World Bank and the Ministry of Higher and Tertiary Education, Innovation, Science and Technology Department (MHTEISTD), the report acknowledges the ongoing reform efforts that the department has embarked on under its Education 5.0 strategy to revitalize higher and tertiary education through the five pillars of Teaching, Research, Community Service, Innovation, and Industrialization. The report also finds that throughout the past decade, Zimbabwe has sustained a high level of public education spending, including spending on tertiary education, relative to the size of its economy. The macro-economic challenges in that last two years have however seen significant decline in education spending both as a percentage of total government expenditure and as a percentage of gross domestic product. “The government’s longstanding commitment to education spending reflects the importance of human-capital development as a national cultural value. As we are fully cognizant of the ever-changing world in which we operate we now seek to transform our Tertiary Education to meaningfully impact economic productivity and workforce skills development,” said Professor Fanuel Tagwira, Permanent Secretary, MHTIESTD. Th education analysis underscores the recent World Bank Digital Economy Diagnostic for Zimbabwe launched in May, which revealed that Zimbabwe is facing a significant skills deficit in science and technology-linked job roles, including digital skills.
    [Show full text]
  • Global COVID-19 Wastewater Monitoring Efforts, Equity, and Gaps
    medRxiv preprint doi: https://doi.org/10.1101/2021.03.14.21253564; this version posted March 17, 2021. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission. Show us the Data: Global COVID-19 Wastewater Monitoring Efforts, Equity, and Gaps Colleen C. Naughton*1, Fernando A. Roman, Jr.1, Ana Grace F. Alvarado1, Arianna Q. Tariqi1, Matthew A. Deeming1, Kyle Bibby2, Aaron Bivins2, Joan B. Rose3, Gertjan Medema456, Warish Ahmed7, Panagis Katsivelis8, Vajra Allan9, Ryan Sinclair10, Yihan Zhang11, Maureen N. Kinyua11 *Corresponding Author [email protected] 1Department of Civil and Environmental Engineering, University of California at Merced, Merced, CA 95343, USA 2Department of Civil & Environmental Engineering & Earth Science, University of Notre Dame, 156 FitZpatrick Hall, Notre Dame, IN, 46556, USA. 3Department of Fisheries and Wildlife, Michigan State University, East Lansing, Michigan 48824, USA 4KWR Water Research Institute, Groningenhaven 7, Nieuwegein, 3433 PE, the Netherlands 4Delft University of Technology, Stevinweg 1, Delft, 2628 CN, the Netherlands 6Michigan State University, 1405 S Harrison Rd, East-Lansing, Michigan, 48823, USA 7CSIRO Land and Water, Ecosciences Precinct, 41 Boggo Road, QLD 4102, Australia. 8Venthic Technologies, Kipoupoleos 129, Peristeri, Athens, Greece 9PATH 2201Westlake Avenue, Suite 200 Seattle, WA 98121, USA 10Schools of Public Health and Earth and Biological Sciences, Loma Linda University Loma Linda, CA 92350, USA 11Department of Civil and Environmental Engineering, University of California at Davis, Davis, CA 95616, USA Abstract (200 words) A year since the declaration of the global coronavirus disease 2019 (COVID-19) pandemic there have been over 110 million cases and 2.5 million deaths.
    [Show full text]
  • 1 SARS-Cov-2 Wastewater Surveillance for Public Health Action
    Preprints (www.preprints.org) | NOT PEER-REVIEWED | Posted: 6 April 2021 doi:10.20944/preprints202104.0167.v1 SARS-CoV-2 Wastewater Surveillance for Public Health Action: Connecting Perspectives from Wastewater Researchers and Public Health Officials During a Global Pandemic Jill S. McClary-Gutierrez1†, Mia C. Mattioli2, Perrine Marcenac2, Andrea I. Silverman3, Alexandria B. Boehm4, Kyle Bibby5, Michael Balliet6, Francis L. de los Reyes III7, Daniel Gerrity8, John F. Griffith9, Patricia A. Holden10, Dimitrios Katehis11, Greg Kester12, Nathan LaCross13, Erin K. Lipp14, Jonathan Meiman15, Rachel T. Noble16, Dominique Brossard17*, Sandra L. McLellan1* 1School of Freshwater Sciences, University of Wisconsin-Milwaukee, Milwaukee, WI, USA 2Waterborne Disease Prevention Branch, Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, USA 3Department of Civil and Urban Engineering, New York University Tandon School of Engineering Brooklyn, NY, USA 4Department of Civil and Environmental Engineering, Stanford University, Stanford, CA, USA 5Department of Civil and Environmental Engineering and Earth Sciences, University of Notre Dame, Notre Dame, IN, USA 6County of Santa Clara, Department of Environmental Health, San Jose, CA, USA 7Department of Civil, Construction, and Environmental Engineering, North Carolina State University, Raleigh, NC, USA 8Applied Research and Development Center, Southern Nevada Water Authority, Las Vegas, NV, USA
    [Show full text]
  • SARS-Cov-2 Wastewater Surveillance for Public Health Action
    Article DOI: https://doi.org/10.3201/eid2709.210753 SARS-CoV-2 Wastewater Surveillance for Public Health Action Appendix Key Wastewater Surveillance Terms Grab samples Samples collected as a single “grab” volume at a single point in time Composite samples Samples collected by pooling multiple grab samples over a set time period. Flow- weighted composite samples are pooled after set flow intervals (e.g., one sub-sample per 200,000 gallons of flow); composite samplers refer to instruments used to automatically collect and pool sample volumes at specific intervals to create a composite sample Sewer transit time The average time for sewage to travel from an upstream source (e.g., toilet flush) to a downstream sampling point (e.g., treatment plant) Solids The nonaqueous fraction of sewage, which may be in the untreated sewage sample or accumulated during the treatment process Method controls A range of additional measurements needed to ensure method integrity and appropriate interpretation of SARS-CoV-2 RNA concentration data, including a matrix recovery control, human fecal normalization, quantitative measurement controls, and controls to assess molecular method inhibition Replication The same procedure performed multiple times to assess precision of the measurement Uncertainty Uncertainty can refer to unknown relationships between a measurement and another metric, such as diagnosed cases. Uncertainty can also be introduced because of variability in measurements due to representative sampling, technical precision, or instrument error. Examples of How Wastewater Data Were Used by Public Health Implementers to Support Their COVID-19 Response Wisconsin The Wisconsin Department of Health Services (WI DHS) initiated a statewide SARS- CoV-2 wastewater testing program in collaboration with the Wisconsin State Laboratory of Hygiene and the University of Wisconsin-Milwaukee.
    [Show full text]
  • HZS C2BRNE DIARY – January 2021
    1 HZS C2BRNE DIARY – January 2021 www.cbrne-terrorism-newsletter.com 2 HZS C2BRNE DIARY – January 2021 HZS C2BRNE DIARY– 2021© January 2021 Website: www.cbrne-terrorism-newsletter.com Editor-in-Chief BrigGEN (ret.) Ioannis Galatas MD, MSc, MC (Army) PhD cand Consultant in Allergy & Clinical Immunology Medical/Hospital CBRNE Planner & Instructor Senior Asymmetric Threats Analyst Manager, CBRN Knowledge Center @ International CBRNE Institute (BE) Senior CBRN Consultant @ HotZone Solutions Group (NL) Athens, Greece Contact e-mail: [email protected] Editorial Team ⚫ Bellanca Giada, MD, MSc (Italy) ⚫ Hopmeier Michael, BSc/MSc MechEngin (USA) ⚫ Kiourktsoglou George, BSc, Dipl, MSc, MBA, PhD (UK) ⚫ Photiou Steve, MD, MSc EmDisaster (Italy) ⚫ Tarlow Peter, PhD Sociol (USA) A publication of HotZone Solutions Group Prinsessegracht 6, 2514 AN, The Hague, The Netherlands T: +31 70 262 97 04, F: +31 (0) 87 784 68 26 E-mail: [email protected] DISCLAIMER: The HZS C2BRNE DIARY® (former CBRNE-Terrorism Newsletter), is a free online publication for the fellow civilian/military CBRNE First Responders worldwide. The Diary is a collection of papers/articles related to the stated thematology. Relevant sources/authors are included and all info provided herein is from open Internet sources. Opinions and comments from the Editor, the Editorial Team or the authors publishing in the Diary do not necessarily represent those of the HotZone Solutions Group (NL) or the International CBRNE Institute (BE). www.cbrne-terrorism-newsletter.com 3 HZS C2BRNE DIARY – January 2021 www.cbrne-terrorism-newsletter.com 4 HZS C2BRNE DIARY – January 2021 www.cbrne-terrorism-newsletter.com 5 HZS C2BRNE DIARY – January 2021 Editorial Brig Gen (ret.) Ioannis Galatas, MD, MSc, MC (Army) Editor-in-Chief HZS C2BRNE Diary Dear Colleagues, New Year, Blank Page? effects and duration of effectiveness of vaccination.
    [Show full text]
  • Wastewater-Based Epidemiology (WBE) and Viral Detection in Polluted Surface Water: a Valuable Tool for COVID-19 Surveillance—A Brief Review
    International Journal of Environmental Research and Public Health Review Wastewater-Based Epidemiology (WBE) and Viral Detection in Polluted Surface Water: A Valuable Tool for COVID-19 Surveillance—A Brief Review Maria de Lourdes Aguiar-Oliveira 1,* , Aline Campos 2 , Aline R. Matos 1 , Caroline Rigotto 3, Adriana Sotero-Martins 4, Paulo F. P. Teixeira 5 and Marilda M. Siqueira 1 1 Laboratory of Respiratory Viruses and Measles, IOC, Oswaldo Cruz Foundation-RJ, National Reference Laboratory for Influenza and COVID-19 for the Brazilian Ministry of Health (MoH) and World Health Organization (WHO), Av. Brasil, 4365 Manguinhos, Rio de Janeiro CEP 21040-360, Brazil; aline.matos@ioc.fiocruz.br (A.R.M.); mmsiq@ioc.fiocruz.br (M.M.S.) 2 State Center for Health Surveillance, Rio Grande do Sul State Department of Health. Av. Ipiranga, 5400, Porto Alegre CEP 90610-000, Rio Grande do Sul, Brazil; [email protected] 3 Laboratory of Molecular Microbiology, Feevale University, ERS-239, 2755, Novo Hamburgo CEP 93525-075, Rio Grande do Sul, Brazil; [email protected] 4 Department of Sanitation and Environmental Health, National School of Public Health Sergio Arouca (ENSP), Oswaldo Cruz Foundation-RJ, Av. Brasil, 4365 Manguinhos, Rio de Janeiro CEP 21040-360, Brazil; adrianasotero@ensp.fiocruz.br 5 Former World Health Organization WHO/PAHO Regional Advisor on Water and Sanitation, Environmental Health, Porto Alegre CEP 90035-002, Rio Grande do Sul, Brazil; [email protected] * Correspondence: lourdes.oliveira@fiocruz.br Received: 23 September 2020; Accepted: 21 October 2020; Published: 10 December 2020 Abstract: SARS-CoV-2 is the causative agent of the current COVID-19 pandemic.
    [Show full text]
  • ACHA COVID-19 “Ask the Expert” Series: Wastewater Surveillance September 25, 2020 Guest Speakers
    ACHA COVID-19 “Ask the Expert” Series: Wastewater Surveillance September 25, 2020 Guest Speakers: Amy E. Kirby, PhD, MPH Environmental Microbiologist, National Wastewater Surveillance System Lead Centers for Disease Control and Prevention R. Sean Norman, MS, PhD Associate Professor, Director, Molecular Microbial Ecology Laboratory Department of Environmental Health Sciences, Arnold School of Public Health, University of South Carolina Kacey C. Ernst, MPH, PhD Professor and Program Director of Epidemiology, Distinguished Scholar Department of Epidemiology and Biostatistics, College of Public Health University of Arizona Moderator: Gerri Taylor, MS, APRN-BC, FACHA Former Associate Dean for Health, Counseling and Health Promotion and Director of the Health Center at Bentley University, ACHA COVID-19 Taskforce Co-Chair National Wastewater Surveillance System Science to Implementation Amy E. Kirby, PhD MPH Community Interventions and Critical Populations Task Force COVID-19 Response American College Health Association Webinar September 25, 2020 cdc.gov/coronavirus Wastewater Surveillance | Public Health Toolbox . Wastewater is an efficient pooled sample of community (or sub-community) infection prevalence . Captures sub-clinical infections . Independent of healthcare-seeking behavior and testing access . Data available within days of shedding onset versus up to 2-week lag for other surveillance data SARS-CoV-2 Sewage Assessment | Trend classification NWSS | Launches In September Sewage Surveillance Data Current potential: based on state of the science . Provide county and sub-county level total infection trends . Leading indicator of potential infection increases following reopening of communities . Early warning to inform re-closure decisions – particularly for high-risk facilities like senior living centers, university campuses, prisons, nursing homes . Tracking virus evolution and global origin upon emergence in US More data needed: estimating overall daily infection prevalence within a sewershed COVID-19 Sewage Assessment | Limitations .
    [Show full text]
  • Sewage Systems Surveillance for SARS-Cov-2: Identification of Knowledge Gaps, Emerging Threats, and Future Research Needs
    pathogens Review Sewage Systems Surveillance for SARS-CoV-2: Identification of Knowledge Gaps, Emerging Threats, and Future Research Needs Fatemeh Amereh 1,2 , Masoud Negahban-Azar 3,*, Siavash Isazadeh 4, Hossein Dabiri 5, Najmeh Masihi 1, Mahsa Jahangiri-rad 6 and Mohammad Rafiee 1,2,* 1 Environmental and Occupational Hazards Control Research Center, Shahid Beheshti University of Medical Sciences, Tehran 35511, Iran; [email protected] (F.A.); [email protected] (N.M.) 2 Department of Environmental Health Engineering, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran 35511, Iran 3 Department of Environmental Science and Technology, University of Maryland, College Park, MD 20740, USA 4 Environmental Service, Suez Water North America, Paramus, NJ 07652, USA; [email protected] 5 Department of Medical Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran 35511, Iran; [email protected] 6 Water Purification Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran 19168, Iran; [email protected] * Correspondence: [email protected] (M.N.-A.); rafi[email protected] (M.R.); Tel.: +1-(301)-405-1188 (M.N.-A.); +98-(21)-224-32-040 (M.R.) Citation: Amereh, F.; Abstract: The etiological agent for novel coronavirus (COVID-19, Severe Acute Respiratory Syn- Negahban-Azar, M.; Isazadeh, S.; drome Coronavirus 2 (SARS-CoV-2), not only affects the human respiratory system, but also the Dabiri, H.; Masihi, N.; Jahangiri-rad, gastrointestinal tract resulting in gastrointestinal manifestations. The high rate of asymptomatic M.; Rafiee, M. Sewage Systems infected individuals has challenged the estimation of infection spread based on patients’ surveil- Surveillance for SARS-CoV-2: lance, and thus alternative approaches such as wastewater-based epidemiology (WBE) have been Identification of Knowledge Gaps, proposed.
    [Show full text]