complete. I strongly (ecommend this work; it is the best, cur formedin 1982and 1983.Respectedleadersintheirfieldshave rently available book on skeletal scintigraphy. given their opinions of capability and limitations of magnetic resonance imaging and spectroscopy in clinical practice. The MYRON L. LECKLITNER bookletis mostvaluableforthosewithmoderateto significant University ofSouth Alabama experiencealready in these techniques. Mobile, Alabama The historicaloverviewchapter is meaningfulintroductory reading for scientists, physicians, and technologists at any level of backgroundand experience.However,the sevenchapters NUCLEAR MAGNETIC RESONANCE AND ITS related to basic science instrumentation, flow imaging, and CLINICAL APPLICATIONS. real-time imaging have extensive mathematical and technical R.E. Steiner, G.K. Radda, Eds. New York, Churchill Liv detail and are not likely to be appreciated by most medical ingstone for the British Council, British Medical Bulletin imaging professionals, unless there has been a profound corn 40(2):113-206,1984 mitment to the understanding of the basic principles involved and/or significantexperiencein utilization of NMR instru This 93 page booklet represents a concise review ofthe state mentation. In that regard, this booklet, as a whole, is not likely of the art in 1984of recentdevelopmentsand biomedicalap to be of direct benefit to the beginner in NMR imaging or plications of nuclear magnetic resonance imaging and spec spectroscopy. At the same time, because of the summary troscopy.A distinguishedpanelofauthorshasbeenassembled and lack of comprehensivedetail, it alsodoesnot serveas an by twointernationallyknownauthoritiesin the field:Professor adequate overview for the NMR spectroscopist, biochemist, Robert Steiner, Hammersmith Hospital, representing con physiologist, or experienced functional imaging physician. siderable clinical experience and expertise; and Dr. George The seven clinical chapters do represent interesting, pri Radda,oneofthebestknownbiochemistsinthefieldofnuclear manly anecdotal, experiences with a variety of cases illus magnetic resonance spectroscopy. The booklet is divided into trating capability and principles. Understandably, these lack four basicparts: I) a historicalreview;2) a conciseoverview someof the important developmentsthat havehad an impact of physicalprinciples,instrumentation,and safetyaspects;3) since 1982—1983.For example, more recent developments a review of spectroscopy; and 4) clinical results in several which are not discussed in this book include surface coil differenceorgan systems. imaging; multislice, multiecho pulse sequence techniques; The historicalreviewisverywellpresentedmovingfromthe externalcontrastenhancedNMR imagingtechniques;andthin Nobel Laureates, Professors Bloch and Purcell, through the slice techniques. In addition, there is a paucity of data in this historical development of magnetic resonance spectroscopy and report related to the roleof NMR imagingand spectroscopy imaging applications, and demonstrating the quality of images in the larger diagnostic world, including in 1982—1983.This introduction is written by Professor Ray correlative imaging together with observations and measure mondAndrew,formerlyat the Universityof Nottinghamand ments of relative sensitivity, specificity, and accuracy. currently at the University of Florida. Several recent comprehensive textbooks have been corn The basicphysicsand instrumentationchaptersareconcisely pleted describing these techniques, and the value of this par presented by the late Dr. Bill Moore of Harvard University and ticular booklet lies in its attempt to provide opinions from the Universityof Nottingham; by Dr. Peter Hanley, Oxford recognized authorities about the state of the art in 1982-1983. Instruments, Ltd; Dr. David Hoult, National Institutes of The “windowofutility―providedby this book,then,variesto Health; Dr. Ian Young, General Electric Company; Dr. Roger the degreeofexperiencethat the reader bringsin the fieldsof B. Saunders, National Radiological Protection Board; Dr. biochemistry and biophysics. Those who can appreciate the Larry Crooks,Universityof Californiaat San Francisco;and technical detail will derive the greatest benefit from the ma Dr. ,Universityof Nottingham. terial presented. It will, therefore, be a useful addition to the Three spectroscopy chapters have been written describing imaging library of a department as a reference text clinical aspects and the potential of phosphorus-3l, carbon-i3, of the state of the art and the future potentialof NMR spec and sodium-23 nuclear magnetic resonance (NMR) spec troscopy techniques for practicing radiologists, radiology troscopy by leading investigators in the field including Dr. residents, and medical students with existing physical science George Radda at Oxford, Drs. Alger and Shulman of Yale expertise or moderate experience in this area. University, and Drs. Maudsley and Hilal of Columbia C. LEON PARTAIN University. Clinical results involvingseveral different organ systems are Vanderbilt University offered in several chapters including brain studies by Dr. Medical Center Graeme Bydderof HammersmithHospital,pediatricpatients Nashville, Tennessee by Drs. MA. Johnsonand Graeme Bydder,intracranial and orbital tumors by Dr. Brian Worthington, evaluation of the spine by Drs. MT. Modic and M.A. Weinstein, results in the THE PHYSICS OF RADIATION THERAPY. heart and mediastinum by Professor RE. Steiner, evaluation F.M. Khan. Baltimore/London, Williams & Wilkins, 1984, of the liver by Drs. Frank Smith and John Mallard, and 435pp,$59.95 imaging of the retroperitoneum and pelvis by Dr. H. Hricak. This is a textbook dedicated exclusivelyto radiation therapy This concise review is a useful reference as an overview of physics with emphasis on the practical aspects. In the preface, the state of the art in 1984based upondata and imagesper the author statesthat the bookhasbeenwrittenwiththe needs

670 BookReviews The Journal of Nuclear Medicine