Problematic Skin Problematic Skin

Aldavine™5x Borealine® Expert

(INCI: Water (and) Sorbitol (and) (INCI: Glycerin, Acer Rubrum Extract) Ascophyllum Nodosum Extract (and) Borēaline® Expert is the unique active extract of Asparagopsis Armata Extract) red maple bark developed by Bio ForeXtra that Aldavine™5x is a highly potent active from allows for the first time the transfer of Northern the calibrated association of two algae forest natural properties to skin care. Polysaccharides. Aldavine™ effectively Borēaline® Expert is the first fully sustainable targets proinflammatory mediators and cosmetic ingredient obtained from recycled red MMPs to protect microcapillary integrity. maple bark that has been clinically tested to Dark circles and eye puffiness is also reduce the appearance of wrinkles whilst reduced by decreasing skin fragility via increasing skin firmness and elasticity to reduce strengthening the Cellular Matrix and the signs of ageing. supporting microvasculature network. We recommend using Aldavine™5x in combination with the African , Recommended usage level: 0.1 - 0.25% Chrysanthellum indicum (Lanachrys), which stimulates lipolysis.

Ideal for the alleviation of dark circles, rosacea, spider veins, sensitive/irritated skin, sun burn, razor burn and after laser treatment.

Recommended usage level: 1 - 5%. 5x : 0.2 - 1 % Canadian Willowherb™ 5C PF COSME-PHYTAMI® CAMU CAMU

(INCI: Water (and) Epilobium Angustifolium (INCI: Glycerin, Dubia Extract) //Stem Extract) Camu Camu fruit offers one of the richest natural Canadian Willowherb™ is a Comos certified sources of Vitamin C, providing the skin with an multi-functional active ingredient that important antioxidant capacity against free contains bioactive molecules such as radicals, which are well-known to be one of the Oenothein B which has 5-α-reductase main causes of premature ageing. Camu Camu is inhibitory activity, anti-oxidant and anti- an ideal active ingredients for mature, stressed bacterial properties. Its primary function is skin and sun protection products as well as toning as a non-steroidal anti-irritant ingredient and exfoliating due to the respective vitamin and with free radical scavaging ability. organic acid content. As a result, Camu Camu are recommended to restore radiance in Canadian Willowherb™ shows strong anti- dull, tired skin. bacterial activity on P. acnes. Its anti-irritant and redness reduction properties show a Recommended usage level: 1-10% strong reduction of skin redness induced by chemicals or UV exposure within 30 minutes.

Ideal for anti-acne, redness, anti-ageing, intimate care, oral care (anti-irritant/ bleeding gums), sun care (reduces UV- induced erythema) and baby care (nappy rash).

Recommended usage level: 1 - 3% CYTOFRUIT® WATERS Green CYTOFRUIT® WATERS Lemon Mandarin (INCI: Citrus Limon Fruit Extract) (INCI: Citrus Nobilis Fruit Extract) CYTOFRUIT® WATERS Lemon is a Cosmos CYTOFRUIT® WATERS Green Mandarin is a certifiable and circular economy fruit water from Cosmos certifiable and circular economy the production of Lemon Juice. The Lemons, fruit water from the production of Green harvested in the Mediterranean are rich in Vitamin Mandarin juice. C, Potassium and Citric Acid.

The fruits are harvested in the Lemon fruits cleanse and exfoliate dull and oily Mediterranean and show precious antiseptic skins, whilst refreshing and quenching the skin’s characteristics as well as an anti-stress, thirst to provide a radiant glow. In addition, Lemon making it ideal for use in relaxing, anti- fruit also offers natural anti-bacterial and stress, uplifting, refreshing, anti-depressant, astringent properties. soothing and lenitive applications. Thanks to the presence of oligo-elements, this Thanks to the presence of oligo-elements, CYTOFRUIT® Water could sustain skin biological this CYTOFRUIT® Water could sustain skin benefits through an improvement of cell vitality, a biological benefits through an improvement protection against external agents or a of cell vitality, a protection against external physiological improvement. agents or a physiological improvement. Recommended usage level: 1 - 100% Recommended usage level: 1 - 100% Dendriclear™ Ecoslim™

(INCI: Glycerin, Water, Polylysine) (INCI: Caffeine (and) Coffea Arabica (Coffee) Extract (and) Lecithin) Dendriclear™ is a very innovative active ingredient against the factors responsible Ecoslim™ is the ideal solution to give a radiant for acne. Advances in our understanding of look back. Stress, lack of sleep, alcohol and the microbiome simply decreasing the cigarette smoke are some of the most common C.acnes quantity is no longer key to clearing factors responsible for tired-looking eyes. Dark acne but rebalancing its distribution circles, bags under the eyes, fine lines and between acneic and non-acneic strains is! dehydration of the eye contour are the visible signs. Composed of a unique patented lysine dendrimer obtained with a green chemistry Ecoslim™ contains Caffeine to constrict blood manufacturing process, Dendriclear™ is able vessels, improve drainage and reduce fat excess to selectively weaken the acneic C. acnes to fight dark circles and puffiness; Coffee extract, strains to favour growth of non-acneic an antioxidant to counteract free radicals strains to gently rebalance the acnebiome™ responsible for puffiness, inflammation and ageing of acne-prone skin in order to recover a and Lecithin for its hydrating and film-forming healthier microbiota and reduce the properties to reinforce the cutaneous barrier of appearance of acne for clear and flawless the fragile eye contour. skin. Recommended usage level: 0.50 - 5% With this breakthrough microbiota-friendly mechanism of action, Dendriclear™ is the next generation of active ingredients in the battle against acne and is a gentle alternative with no undesired side effects, unlike traditional acne-prone skin solutions.

Recommended usage level: Preventive action: 0.1 - 0.2%; Intensive action: 0.2 - 0.4% Evicare® wintergreen Exo-H™

(INCI: Salicylic Acid) (INCI: Butylene Glycol (and) Alteromonas Ferment Filtrate) Evicare® wintergreen is a natural antimicrobial active and preservative. Exo-H™ restores Hyaluronic Acid secretion in aged Salicylic acid is well known in the industry skin cells, stimulates lipid synthesis, supports the and used as a preservative but even more DEJ and induces Filaggrin expression in the skin. as an active with specific function as anti- Exo-H™ helps maintain an optimal skin barrier dandruff agent, anti-acne active and for its function and has excellent hydrating properties keratinolytic affect. Evicare® wintergreen is due to its action on natural moisturising factors 100% natural and sourced sustainably from and lipid synthesis, making it ideal for dry skin. the wintergreen shrub as a by-product from aroma sourcing. It is moderately water When used together, Exo-H™ and Exo-T™ soluble and can simply be added to the regenerate skin texture and natural hydration for water phase. It is often used in anti-acne a smooth, radiant and healthy looking skin and anti-dandruff products as a main active. complexion.

Recommended usage level: 0.5 - 2.5% Recommended usage level: 1 - 3%

HydroSal™ SalCool Isoflavones 150

(INCI: Propylene Glycol, Methyl Diisopropyl (INCI: Glycine Soja (Soybean) Germ Extract) Propionamide, Menthyl Lactate, Ethyl Isoflavones 150 contains 10–12% Soybean Menthane Carboxamide, Isoflavones (Daidzin, Genistin, Glycitin and Hydroxypropylcellulose, Isopropyl Palmitate, Aglucone) in a concentrated format. Especially Phenoxyethanol, Ethylhexylglycerin) designed for advanced anti-ageing (60+), it is a HydroSal™ SalCool is a neurocosmetic that safe substitute for the female hormone, Oestrogen. provides the perception of freshness without Isoflavones 150 reduces Collagen glycation to physically dropping the temperature of the decrease wrinkles and improve elasticity whilst skin and without the menthol odour, like decreasing skin blood flow to reduce skin redness comparable cooling products. and calm sensitive skin. Ideal for mature and The technology enables the extended, “time- menopausal skin release” performance because ingredients Recommended usage level: 1 - 3% act in a non-competitive manner on the different sensory nerve endings of the skin to extend the sensation without getting adapted to the sensation.

Suitable for water-based and hydroalcoholic applications such as, lotions, hair and body washes, shaving gels, oral care and topical pain relief.

Recommended usage level: 7.0 - 15.0% Kahai Oil Kollaren®

(INCI: Caryodendron orinocense nut oil ) (INCI: Water (and) Dextran (and) Tripeptide-1)

Kahai Oil is a 100% natural anti-aging oil, Kollaren® is a biomimetic Peptide derived from a extracted by cold pressing the nuts of the signal Peptide. Kollaren® increases the firmness Cacay tree. Its high content of natural of the skin by activating the Extracellular Matrix Vitamin E, F & Retinol nourishes, softens Proteins synthesis (Collagen, Elastin, Fibronectin and repairs damaged skin and hair. Kahai and Laminin). With its tissue repair properties, Oil revitalises the skin returns radiance, Kollaren® encourages tissue renewal and restores reduces fine lines and wrinkles, and giving it the biomechanical properties of the skin. a long lasting hydration. Kollaren® is the perfect tool to fight the ageing For haircare, it provides shine and silkiness, process, reduce the appearance of sagging skin, and also prevents split ends. Kahai Oil wrinkles and other manifestations of skin ageing. contains 50% more Vitamin E and twice the amount of Linoleic Acid than Argan oil; and Recommended usage level: 1 - 10% it has 3 times more Retinol than Rose Hip Oil.

Recommended usage level: Various Lanablue® Lecigel™

(INCI: Sorbitol (and) Water (and) Algae (INCI: Sodium Acrylates Copolymer (and) Lecithin) Extract) Lecigel™ is a gelling agent with emulsifying and Lanablue® blue colour (no colour when cooling properties (ice-cube-like sensation - formulated) is due to the natural pigment of pleasant and safe alternative to Menthol and Phytosienine. An extract of Endemic Alcohol). It allows the increase in the stability of Cyanophyleae harvested in wild conditions, formulas. Lanablue® has a high content of group B Suitable for both cold and hot processes, it also vitamins, amino acids and specific helps to adjust the viscosity at the end of the pigments. It acts like natural Retinoids formulation process. Easy to use and stable to pH (without the side effects) on Keratinocyte 9, it is compatible with most emulsifiers and is differentiation, thus smoothing and stable over a wide range of pH. densifying the epidermis.

Especially adapted for the formulation of Lanablue® influences different markers gelcreams, it provides the typical ‘Phospholipid such as: Filaggrin, marker of cell touch’ with a cool, soft and non-greasy skin feel. differentiation, it contributes to maintaining skin hydration and liberates natural Recommended usage level: 0.1 - 2% moisturising factors; Loricrin, marker of Corneocyte differentiation; Calgranulin A, Calgranulin B and Psoriasin, markers of basal proliferation, involved in skin repair process; TIMP 1 (Tissue Inhibitor of Metalloproteinase-1), natural inhibitor of Matrix Metalloproteinase (MMP) which regulates the integrity of the Extracellular structure.

Recommended usage level: 1 - 5% Liftessence™ Nature Macadamia Oil

(INCI: Water, Glycerin, Cyathea Cumingii (INCI: Macadamia Ternifolia Seed Oil ) Leaf Extract) Nourishing and emollient properties. Suitable for Liftessence™ is a natural instant skin mature and devitalised skin. tightener from Polysaccharides found in a Recommended usage level: up to 100% New Zealand Fern.

Its specific Polysaccharide composition provides a mechanical lifting effect, which immediately reduces the appearance of fine lines and enhances skin biochemical properties without flaking.

Suitable for neck and eye applications.

Recommended usage level: 1 - 2%

Matipure Oil Free™ Melanostatine®5

(INCI: Magnesium Aluminum Silicate (and) (INCI: Water (and) Dextran (and) Nonapeptide-1) Hydroxyethylcellulose (and) Phospholipids) Melanostatine® 5 is an Oligopeptide with a high Matipure Oil Free™ is a unique patented affinity for MC1-R. biocompatible complex characterised by Melanostatine® 5 is a Biomimetic Peptide highly absorbant porous micro particles antagonist specific to α-MSH (Alpha Melanocyte made of Cellulose Magnesium Silicate and Stimulating Hormone). complexed Phospholipids.

As an antagonist, Melanostatine® 5 competes When Matipure Oil Free™ is applied on the against the natural ligand (α-MSH) on its specific surface of the skin, water slowly evaporates receptor (MC1-R) to prevent any further activation allowing excess sebum to gradually migrate of the Tyrosinase, and thus blocking Melanin inside particles providing an immediate synthesis, stopping unwanted pigmentation, matifying (reduces sebum by 40% after 1 allowing for control over skin tone and brown hour) and purifying effects. Phospholipids spots. China compliant. give smoothness to the skin and avoid a drying effect. Recommended usage level: 4 - 8%

Recommended usage level: 1 - 5% Miniporyl™ MultiSal™ Asta

(INCI: Isopentyldiol, Trifolium Pratense (INCI: Hydrolyzed Corn Starch Octenylsuccinate, (Clover) Flower Extract) Isostearyl Isostearate, Haematococcus Pluvialis Extract, Oryza Sativa (Rice) Hull Powder, Miniporyl™ is extracted from Red Clover Butyrospermum Parkii (Shea) Butter) Extract and titrated in Biochanin A to purify and rebalance skin. The enlargement of Delivery system containing Astaxanthin, which is a pores is caused by Corneocytes retaining naturally occurring blood-red pigment (carotenoid) their nucleus which cause pores to clog. As often found in microalgae. a result skin loses tonicity and firmness. Astaxanthin is a natural anti-inflammatory agent Miniporyl™ improves Keratinocyte with potent antioxidant (6000 times stronger than differentiation to obtain nucleusfree Vitamin C!) properties. It offers anti-ageing effects Corneocytes as well as inhibiting 5α- to reduce wrinkles, degradation of skin elasticity, reductase activity to decrease sebum and age spots (liver spots). production. Overall the size and appearance Astaxanthin may inhibit age-related skin of pores is reduced. deterioration and maintain skin conditions Recommended usage level: 0.5 – 1.0% associated with environmentally induced damage. Preventative face care 1.0 – 2.0% Intensive Recommended usage level: 5% face care MultiSal™ Menthol MultiSal™ Retinol

(INCI: Hydrolyzed Corn Starch (INCI: Retinol, Hydrated Silica, PPG-3 Benzyl Ether Octenylsuccinate, Sodium Starch Myristate, PEI-10) Octenylsuccinate, Menthol, Euphorbia Retinol has been utilised extensively as an anti- Cerifera (Candelilla) Wax, Butyrospermum wrinkle therapy. The molecule acts by inducing Parkii (Shea) Butter, Hydrated Silica) glycosaminoglycan and collagen synthesis, MultiSal® Menthol is specifically designed rejuvenating the firmness and youthful for anhydrous applications that require a appearance of skin. higher temperature in processing, for A challenge regarding the use of Retinol is its instance soap bars or solid AP sticks. susceptibility to oxidation, which ultimately Menthol evaporates at typical processing reduces the potency and limits effectiveness. Due temperatures (around 80°C).The to its ability to enhance skin turnover, Retinol can consequences of this are twofold: 1. Menthol cause irritation on consumers with sensitive skin. vapor is irritating to eyes and lungs, thus filling the production environment with it is MultiSal™ technology is based on double-layered unsafe; 2. Menthol is lost, either reducing encapsulation of retinol. The microsphere ruptures the concentration in the final product, or when the lotion is rubbed into the skin, releasing making it necessary to use more to make it the sub-micron spheres inside. The core is the right concentration. comprised of botanical lipophilic ingredients that partition into the skin, thus modulating the slow MultiSal™ Menthol protects the active from release of the encapsulated retinol over time. evaporation, even under elevated temperatures (up to 160°C). Additionally MultiSal™ Retinol reduces the appearance of fine menthol has a natural, medicinal odour that lines in as little as 2 weeks. MultiSal™ Retinol is may be undesirable for certain applications. recommended for use in anti-ageing and skin rejuvenation products including lotions, creams, MultiSal™ Menthol reduces the unpleasant lip care and cosmetics as well as anti-acne. menthol odour making it more satisfying to the consumer. Suitable for anhydrous Recommended usage level: 1 - 2% applications such as, lotions, body powders, foot care, lip care, analgesics, soap bars and deodorant sticks.

Recommended usage level: Lip care: 1% Skin care: 2 - 5% Pain relief: 4 - 8% Foot care: 7 - 20% MultiSal™ Salicylic Acid MultiSal™ Sebum Control

(INCI: Hydrolyzed Corn Starch (INCI: Sodium Starch Octenylsuccinate, Hydrated Octenylsuccinate, Cocamidopropyl Silica, Acrylates Copolymer, Hydrolyzed Corn Dimethylamine, Glyceryl Stearate, Salicylic Starch Octenylsuccinate, Sodium Hydroxide, Acid, Hydrated Silica, Glycerin) Butyrospermum Parkii (Shea) Butter, Synthetic Wax, Zinc Sulfate.) MultiSal® technology extends the release of Salicylic acid (SA) onto the skin. It exposes MultiSal® Sebum Control is a microencapsulation the skin to very small amounts of acid over technology that provides immediate and long- a longer time, rather than one large amount lasting absorption of excess sebum as well as long- all at once, as is the case with free SA. This term maintenance of sebum production. unique feature allows higher levels of SA to MultiSal™ Sebum Control is highly effective in remain on skin over several hours. The end reducing shine on skin, resulting in a healthy- result is longer-lasting efficacy and acne- looking matte finish that is conducive of blemish- fighting power without irritation. free skin. Ideal for skin care applications such as, Suitable for anhydrous applications such as, lotions, body powders, acne spot treatments and soap bars, on-the-go sticks, body powders, facial wipes. and cosmetics. As well as rinse-off whereby Recommended usage level: 3 - 5% the MultiSal™ technology provides enhanced efficacy due to the cationic nature of the surface of the shell allowing superior adhesion to the skin.

Recommended usage level: Up to 5% (0.5% Salicylic acid) Neutrazen™ Plerasan® Sun

(INCI: Water (and) Butylene Glycol (and) (INCI: Aqua, Maltodextrin, Lolium Perenne Flower Dextran (and) Palmitoyl Tripeptide-8) Extract, Pleurotus Ostreatus Extract, Gluconolactone, Sodium Benzoate, Calcium Neutrazen™ is a true neurocosmetic Gluconate) specifically designed to prevent and reverse signs of neurogenic inflammation. Neutrazen A standardised active ingredient that provides a ™ is an innovative Tri-peptide linked to a natural lentitive and soothing synergy for after lipid for optimal penetration and efficacy. sun applications. It is particularly efficient at modulating post-acute stress linked to sun Neutrazen™ instantly calms and soothes exposure. Its effective film forming activity helps irritated skin and helps to maintain and to prevent further dehydration by water loss. restore a normal skin sensitivity threshold. Ideal for laser treatment as reduces In addition, inflammatory mediators are sensitivity and diminishes pain sensation. modulated, skin and redness is reduced leaving the skin feeling re-energised. Skin moisturisation Recommended usage level: Intensive and microcirculation is also improved. treatment: 2.5% Preventive treatment: 1 to 2.5% Sensitive skin addition: 0.3 to 1% Recommended usage level: 1.0% Progeline™ RED CLAY

(INCI: Glycerin (and) Water (and) Dextran (INCI: Kaolin) (and) Trifluoroacetyl Tripeptide-2) Red Clay by Alban Muller International is a 100% Progeline™ is a 3 Amino acids Biomimetic natural product of mineral origin, as multi-action Peptide of Elafin, an enzyme inhibitor that active ingredient and firming agent. Provides regulates the integrity of the Extracellular antiseptic, purifying, remineralising and Matrix. Progeline™ decreases Progerin an seboregulating activities. Offers significant ageing biomarker of skin cellular absorbent properties (for water, oil) and ion- senescence. By acting directly on a exchange capacities. senescence marker, Progeline™ clinically Red Clay works best on mature and relaxed skin improves the appearance of signs as anti-ageing product. Can also provide natural associated with skin maturation: sagging, colour to cosmetic products according to their slackness and wrinkles. colour and dosage used. A new study has shown that Progeline™ Recommended usage level: Shampoos 1 - 5%; stimulates Sirtuin-1 and Sirtuin-3 production Emulsions 1 - 5%; Masks 10 - 40%; Deodorants 1 - which are responsible for cell longevity and 5% lifespan. In addition, it can reverse the signs of ageing by increasing Pro-collagen I synthesis. In addition, it offers 100% Elastase inhibition; this is important as we cannot stimulate Elastin.

Gold Award winner, In-Cosmetics 2012.

Recommended usage level: Intensive treatment: 2% Body care: 1% Preventive care: 0.5 – 2% RED CLAY ER Riboxyl™

(INCI: Illite, Kaolin) (INCI: Ribose)

This COSMOS certified Red clay is composed Riboxyl™ is a fundamental building block of the of kaolin and illite-type clay. Its red color ATP molecule which is the most important source comes from its rich content in oxidized iron. of cell energy. To function efficiently, the cell must It is attributed with soothing properties and keep its ATP content at a maximum level. virtues ideal for reducing diffuse redness of ™ the skin and bringing luminosity to the Riboxyl is natural D-Ribose, a Pentose that complexion. occurs in all living cells. Generating de novo ATP, it energises and oxygenises skin, reduces Recommended usage level: Shampoos 1 - wrinkles, increases skin elasticity and enhances 5%; Emulsions 1 - 5%; Masks 10 - 40%; complexion. Deodorants 1 - 5%​ Ideal for detox, relaxation and antiburn-out applications.

Recommended usage level: 0.5 - 1%

SalSphere® Even Skin SalSphere® Natural Anti-Blemish

(INCI: Salicylic Acid, PEG-8, (INCI: Water, Butyrospermum Parkii (Shea) Butter, Isostearamidopropyl Ethyldimonium Propanediol, Cocamidopropyl Betaine, Citric Acid, Ethosulfate, Propylene Glycol, Carthamus Pentylene Glycol, Xanthan Gum, Bromelain, Tinctorius (Safflower) Seed Oil, Olea Caprylyl Glycol, Glycerin, Sodium Chloride, Europaea (Olive) Fruit Oil) Euphorbia Cerifera (candelilla) wax, Copernicia Cerifera (Carnauba) Wax, Avena Sativa (Oat) A time release delivery system for salicylic Kernel Flour, Ethylhexylglycerin, Salix Alba acid (SA) to rejuvenate and restore skin. (Willow) Bark Extract, Glycyrrhiza Glabra (Licorice) Leaf Extract, Chamomilla Recutita (Matricaria) Recommended usage level: Cosmetic: Up to Flower Extract) 1.67% ; OTC: 1.67-6.67%; Rx: Over 6.67%

Delivery of natural (89% natural) and botanical ingredients, suitable for sensitive skin, to treat blemishes such as any mark, spot, discoloration, or flaw that appears on the skin.

Dark spots can form from exposure to the sun. They’re most common in people over 50, but can also occur in younger people. Age spots are a type of hyperpigmentation. Melasma is a skin condition, identified by brownish patches, that is very common during pregnancy. It can be brought about by sun exposure and hormonal changes.

Recommended usage level: 5% SalSphere™ Anti-Aging Lift SalSphere™ Aqua Skin

(INCI: Water, Polyvinyl Alcohol, Sodium Coco- (INCI: Fucus Vesiculosus (Seaweed) Extract, Glucoside Tartrate, Theobroma Cacao Caffeine, Urea, Hyaluronic Acid, Butyrospermum (Cocoa) Seed, Beeswax, Euphorbia Cerifera Parkii (Shea) Butter, Glyceryl Stearate, Glycerin, (Candelilla) Wax, Lecithin, Phenoxyethanol, Polysorbate 80, Phenoxyethanol, Ethylhexylglycerin, Tocopherol Acetate, Ethylhexylglycerin, Polyquaternium-67) Niacin, Resveratrol, Dimethyl Sulfone, SalSphere® AquaSkin (98% natural) is specially Glycerin, Punica Granatum Extract, designed to effectively deliver natural moisturising Palmitoyl Tripeptide-5) agents deep into the layers of the skin. The SalSphere® Anti-ageing Lift (AAL) is an technology provides instant and prolonged effective technology that instantly reduces moisturisation to achieve healthy and nourished the appearance of fine lines and treats skin. wrinkles from within for a long-lasting, SalSphere™ AquaSkin can be utilised in a wide younger-looking appearance. variety of formulation types such as, moisturising SalSphere™ AAL visibly reduces the creams and lotions, and hydrating cosmetics. As appearance of fine lines in as little as 10 well as rinse-off conditioners, shampoos, shower minutes and yields a firming sensation that gels and body washes. can be perceived long after application. Recommended usage level: 1 - 5% Suitable for leave-on anti-ageing applications such as, creams, lotions, serums and concealers.

Recommended usage level: 10% SalSphere™ BPO SalSphere™ Clear Skin

(INCI: Water, Benzoyl Peroxide, (INCI: Water, Cocamidopropyl Dimethylamine, Hydroxyethyl Behenamidopropyl Dimonium Salicylic Acid, Lactic Acid, Phenoxyethanol, Chloride, Butyrospermum Parkii (Shea Sodium Hydroxide, Ethylhexylglycerin) Butter) Fruit, Euphorbia Cerifera (Candelilla) SalSphere® Clear Skin is a delivery system Wax) designed to rejuvenate and clear the skin of It is known that BPO is difficult to formulate blemishes. Its ingredients work synergistically to with due to its poor water solubility and high gently exfoliate the skin and provide superior instability. Additionally, while it is a proven moisturisation. antibacterial agent, clinical success of BPO SalSphere™ Clear Skin is an ideal technology for in acne-fighting products is limited and various daily skin care applications such as, face often results in dryness and discomfort. and body washes, lotions, toners and gels. When skin is exposed to a large dose of Recommended usage level: Up to 10% benzoyl peroxide all at once, it can become extremely irritated, resulting in reduced user compliance. Users with sensitive skin may even suffer from burning, itching, peeling and swelling of the skin.

SalSphere™ BPO is a sub-micron encapsulation system of benzoyl peroxide that releases slowly over time for a more potent and effective acne treatment. Suitable for anti-acne products such as, creams, lotions, spot treatments, facial cleansers and sensitive skin.

Recommended usage level: 10 - 40% SalSphere™ Natural Anti- Sculptessence™ Aging (INCI: Water (and) Glycerin (and) Linum (INCI: Apple (Pyrus Malus) Extract, Fruit Usitatissimum (Linseed) Seed Extract Bio: Betula Extract, Grape Seed Extract (Resveratrol), Alba Juice (and) Glycerin (and) Linum Butyrospermum Parkii (Shea) Butter, Usitatissimum (Linseed) Seed Extract) Euphorbia Cerifera (Candelilla) Wax, Sculptessence™ is a natural remodeller derived Polyglyceryl-2 Stearate, Glyceryl Stearate, from Linseed, which compensates for ageing Stearyl Alcohol) disorders in three ways of actions: skin hydration, SalSphere® Natural (95% natural) Anti- stimulation of GAG’s synthesis and protection of ageing is a sub-micron technology Collagen. composed of potent and natural age-fighting Its unique Polyholosides hydrate skin and reverse Polyphenols, Resveratrol and Procyanidin B2. sagging disorders to redesign the outline of the Resveratrol is a potent polyphenol and face without the need for surgery. antioxidant derived from the skin of red Recommended usage level: l 3 - 5% grapes that has been shown to brighten and even out skin tone. Procyanidin B2 from apple extract is another powerful Polyphenol and antioxidant that promotes cell growth and rejuvenation. It also inhibits the formation of Advanced Glycation End- products (AGE) that causes wrinkles and dull skin tone.

Ideal for anti-ageing products such as, lotions, creams, concealers and cleansers.

Recommended usage level: 5 - 10% SKINECTURA™ Tyrostat™

(INCI: Glycerin, Water, Anigozanthos flavidus (INCI: Tyrostat-09: Water (and) Glycerin (and) Extract) Rumex Occidentalis Extract Tyrostat-11: Water (and) Glycerin (and) Rumex Occidentalis Extract SKINectura™ is a certified organic botanical (and) Ascorbic Acid) extract of Australian Kangaroo Paw flower rich in Nectar that boosts Tenascin-X Tyrostat™ is a natural skin whitening agent from synthesis, a new marker in skin Rumex species native to Northern Canada. It is architecture, for optimal reduction in edible, safe and globally registered. Tyrostat™ appearance of wrinkles and sagging skin... inhibits Tyrosinase and has a similar activity to the best secret to age gracefully. Kojic acid. As Tyrostat™ is a plant based skin lightener composition can change from batch to Recommended usage level: 2 - 6% batch, as such every batch is tested for Tyrosinase inhibition efficacy.

Tyrostat™ effectively reduces pigmentation, erythema, tanning and age spots. A skin lightening effect is induced after just 3 weeks.

Two grades are available: Tyrostat™ 09 (offers a minimum of 75% inhibition) and Tyrostat™ 11 (contains Ascorbic acid and guarantees a 95% inhibition of Tyrosinase).

Recommended usage level: 1 - 3% Vegan DDS Alpha Arbutin Vegan DDS Oligo HA

(INCI: Aqua, Mannitol, Phosphatidylcholine, (INCI: Aqua, Mannitol, Phosphatidilcoline, Glycerin, Glycerin, Alpha-Arbutin, Cetyl Alcohol, Decyl Hyaluronic Acid, Cetyl Alcohol, Decyl Glucoside, Glucoside, Potassium Sorbate, Sodium Potassium Sorbate, Sodium Benzoate, Xanthan Benzoate, Xanthan Gum, Sodium Chloride) Gum, Sodium Chloride)

Alpha Arbutin is a pure biosynthetic and Hyaluronic Acid is a structural polysaccharide hydro soluble active that activates skin which is naturally present in the skin and which lightening and unifies all skin types by can capture and retain large amounts of water. As blocking the synthesis of melanin pigments the body ages, the presence of this substance is which inhibit the enzymatic oxidation of reduced considerably and by the age of 50 only tyrosine and the DOPA. 50% of the endogenous hyaluronic acid remains.

Alpha-Arbutin is encapsulated in INdermal’s As a consequence, the skin loses its volume and Deep Delivery System (DDS) ensuring it is firmness and suffers an increased wrinkling effect. specifically delivered to the deepest strata Oligo Hyaluronic Acid is obtained via an advanced of the epidermis for a more intense and and complicated full degradation process with precise effect on the structures and cells hyaluronidase of hyaluronic acid, achieving sizes located there. smaller than 10Kda (20 times less than that known as the “low molecular weight hyaluronic The use of DDS enables up to twelve times acid”). the amount of active ingredient to reach the interior of the skin compared to when This specific type of hyaluronic acid can be applied freely. transported by the nanovesicles until its delivery to the skin levels where it replaces lost hyaluronic Recommended usage level: 1 - 10% acid, captures water thereby recovering the skin volume, reduces wrinkle depth and restores the elasticity and tonicity more typically associated with much younger skin.

Recommended usage level: 1 - 10% Vegan DDS Retinol Vegan DDS Tranexamic

(INCI: Aqua, Mannitol, Phosphatidilcoline, (INCI: Aqua, Mannitol, Phosphatidilcoline, Glycerin, Glycerin, Retinyl Palmitate, Cetyl Alcohol, Tranexamic Acid, Cetyl Alcohol, Decyl Glucoside, Potassium Sorbate, Sodium Benzoate, Decyl Potassium Sorbate, Sodium Benzoate, Glucoside, Lauryl Glucoside, Xanthan Gum, Niacinamide, Xanthan Gum, Sodium Chloride) Sodium Chloride) Tranexamic Acid is a widely known molecule in Retinyl Palmitate is an ester of vitamin A medicine which is normally used as an and is one of the most reliable ways to antifibrinolytic owing to its ability to inhibit provide the skin with vitamin A. On delivery plasmin. This same property is used in cosmetics to the deep skin levels, Retinyl converts to to reduce pigmentations since plasmin is involved Retinol (Vitamin A) which in turn converts to with melanogenesis. Furthermore, Tranexamic Retinal (Retinaldehyde), before finally Acid acts on keratinocytes which contain melanin, converting to Retinoic Acid. interrupting the inflammatory process that produces blemishing following external Its ability to stimulate the production of aggressions or injuries such as acne. hyaluronic acid, collagen and elastin is why it is considered one of the most potent anti- Finally, it also reduces increased vascularisation aging active ingredients. It also accelerates which always accompanies a recurrent the cell regeneration process, improving the hyperpigmentation such as melasma. These three general appearance and texture of the skin modes of action of Tranexamic Acid, together with and minimising the pore size. For this the ability of Niacinamide (Vit.B3) to inhibit the reason, together with its ability to regulate transfer of melanosomes and protect the DNA sebum production, it is commonly found in from UV damage, provide a potent treatment for acne treatment products. all types of blemishes. It is particularly effective in the treatment of photo induced pigmentations Furthermore, it represses the production of such as, Melasma and Liver spots. melanin thereby reducing the number and intensity of skin blemishes. Retinyl Encapsulated within INdermal's Deep Delivery Palmitate is encapsulated in the Deep System (DDS) it enables the Tranexamic Acid to Delivery System (DDS) where it is be delivered to the deepest strata of the specifically delivered to the deepest strata epidermis for a more intense and precise effect on of the epidermis for a more intense and the structures and cells located there. The use of precise effect on the structures and cells DDS enables up to twelve times the amount of located there. The use of DDS enables up to active ingredient to reach the interior of the skin twelve times the amount of active compared to when applied freely ingredient to reach the interior of the skin Recommended usage level: 1 - 10% compared to when applied freely.

Recommended usage level: 1 - 10% Vegan FDS Zinc PCA WildPlum Harvest™ AF

(INCI: Aqua, Mannitol, Phosphatidilcoline, (INCI: Glycerin, Aqua, Ferdinandiana Glycerin, Zinc PCA, Cetyl Alcohol, Sodium Fruit Extract, Podocarpus Elatus Fruit Extract, Benzoate, Sorbitan Oleate, Polysorbate 80, Pleiogynium Timorense Fruit Extract) Xanthan Gum, Stearamine, Sodium ™ Chloride, Dimyristoyl Phosphatidylcholine) WildPlum Harvest AF is a unique combination of Australian Superfruits, specially selected to Zinc PCA is the zinc salt of the L-PCA hydrate, nourish and rejuvenate mature skin for a (pyrrolidine carboxylic acid) a doubly active radiant and younger looking skin. complex that provides the skin and hair with the beneficial effects of the zinc and L-PCA. Recommended usage level: 1 - 2%

Zinc is involved not only in the synthesis of the nucleic acids, including the DNA, but also in the synthesis of proteins, cell division and in the structure and coenzymatic activation of many key molecules in the body and the skin. It also prevents the development of microbial infections thanks to its considerable antiseptic properties.

It has been shown that zinc reduces sebum secretion by inhibiting the 5 α- reductase. When joining L-PCA to an active molecule such as zinc, it becomes a physiological vector which optimises its bioavailability and in addition acts as a signalling molecule to stimulate the epidermal differentiation and strengthen the skin barrier function.

Recommended usage level: 1 - 10% β-White™

(INCI: Water (and) Butylene Glycol (and) Hydrogenated Lecithin (and) Sodium Oleate (and) Oligopeptide-68 (and) Disodium EDTA)

ß-White™ is a TGF-ß Biomimetic peptide encapsulated in a Liposome vehicle. It differentiates itself from other traditional whitening agents with its unique inhibitory action on the MITF (responsible for Tyrosinase and the enzymes involved in the pigment cascade TRP-1 and TRP-2) cellular pathway to decrease constitutive and facultative pigmentation with an excellent safety profile.

Compatible with AHA to enhance exfoliation, increase penetration of peptide and aid whitening.

Recommended usage level: Intensive whitening: 2.5 - 5% Lightening care and skin illuminator: 0.5 - 1% Corrective care and age-spot: 1 - 2.5% Contact Us

Interested? Then contact the Infinity team for more information:

T: 01344 354 900

E: [email protected]

W: infinity-ingredients.co.uk