SRBR 2004 Program Book
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Ninth Meeting Society for Research on Biological Rhythms Program and Abstracts SRS/SRBR June 23, 2004 SRBR June 24–26, 2004 Whistler Resort • Whistler, British Columbia SOCIETY FOR RESEARCH ON BIOLOGICAL RHYTHMS i Executive Committee Editorial Board Ralph E. Mistleberger Simon Fraser University Steven Reppert, President Serge Daan University of Massachusetts Medical University of Groningen School Larry Morin SUNY, Stony Brook Bruce Goldman William Schwartz, President-Elect University of Connecticut University of Massachusetts Medical Hitoshi Okamura Kobe University School of Medicine School Terry Page Vanderbilt University Carla Green, Secretary Steven Reppert University of Massachusetts Medical University of Virginia Ueli Schibler School University of Geneva Fred Davis, Treasurer Mark Rollag Northeastern University Michael Terman Uniformed Services University Columbia University Helena Illnerova, Member-at-Large Benjamin Rusak Czech. Academy of Sciences Advisory Board Dalhousie University Takao Kondo, Member-at-Large Timothy J. Bartness Nagoya University Georgia State University Laura Smale Michigan State University Anna Wirz-Justice, Member-at-Large Vincent M. Cassone Centre for Chronobiology Texas A & M University Rae Silver Columbia University Journal of Biological Russell Foster Rhythms Imperial College of Science Martin Straume University of Virginia Jadwiga M. Giebultowicz Editor-in-Chief Oregon State University Elaine Tobin Martin Zatz University of California, Los Angeles National Institute of Mental Health Carla Green University of Virginia Fred Turek Associate Editors Northwestern University Eberhard Gwinner Josephine Arendt Max Planck Institute G.T.J. van der Horst University of Surrey Erasmus University Paul Hardin Michael Hastings University of Houston David R. Weaver MRC, Cambridge University of Massachusetts Medical Helena Illerova Center Ken-Ichi Honma Czech. Academy of Sciences Hokkaido University School of Anna Wirz-Justice Medicine Carl Johnson University of Basel Vanderbilt University William J. Schwartz Phyllis C. Zee University of Massachusetts Medical Jennifer Loros Northwestern University School Dartmouth Medical Center Irving Zucker Michael Young University of California, Berkley Rockefeller University iI NINTH MEETING PROGRAM AND ABSTRACTS Ninth Meeting Society for Research on Biological Rhythms Program and Abstracts SRS/SRBR June 23, 2004 SRBR June 24–26, 2004 Whistler Resort • Whistler, British Columbia The SRBR wishes to thank the Program Committee Organizing Committee following for their contributions: Vincent M. Cassone, Chair Steven M. Reppert, SRBR President Deborah Bell-Pedersen William J. Schwartz ALA Scientific Instruments David Earnest Rae Silver American Laboratory Products Shizufumi Ebihara Lawrence P. Morin Mini-Mitter Company Paul D. Hardin Carla Green National Aeronautics and Space Administration Elizabeth Klerman Fred Davis National Institutes of Mental Health Michael Lehman National Science Foundation Ralph Mistlberger Sage Publications SOCIETY FOR RESEARCH ON BIOLOGICAL RHYTHMS iII iV NINTH MEETING PROGRAM AND ABSTRACTS Table of Contents General Information . 2 President’s Welcome Registration Information Information and Message Desk About the Village Conference Centre Information Instructions to Presenters Social Events General Program Schedule . 4 Scientific Program . 7 Abstracts . 30 Index of Authors . 181 Maps . 189 Whistler Village Conference Centre SOCIETY FOR RESEARCH ON BIOLOGICAL RHYTHMS 1 General Information Registration Meeting registration will take place on President’s Welcome Wednesday, June 23 from 17:00 until 18:00 The field of circadian biology continues to move and on Thursday, June 24 from 8:00 until 11:00 forward at a fast pace. The research presented at and 15:00 until 17:00 in the Great Room of the this year’s biennial SRBR meeting reflects the Whistler Conference Centre. Hotel check-in ongoing, important discoveries. Whistler, British will be at the individual properties. Columbia, Canada, is a welcoming and refreshing Early Registration: new venue. Postmarked by May 7, 2004 Organizing this meeting would not have been possible without generous contributions from each SRBR Member: $325 member of the Organizing Committee. I need to Non-Member: $375 single out Vinnie Cassone for doing more than his share as Program Committee Chair. I also thank SRBR Student Member: $165 Scott Miller and his associates at the Office of Non-Member Student: $190 Continuing Education, University of Illinois at Guest Registration: $75 Urbana-Champaign for providing the necessary infrastructure. Late Registration: Postmarked after May 7, 2004 Finally, I want to thank every one in attendance— your participation is what makes this meeting a SRBR Member: $350 success. Thank you for your support. Non-Member: $400 Steven Reppert SRBR Student Member: $175 President, SRBR Non-Member Student: $200 Guest Registration: $100 Membership rates apply to individuals who have joined SRBR before the meeting and have paid current dues. Student rates apply to registrants who will not have received their Ph.D. or M.D. degree at the time of the meeting. Registered participants and guests are invited to the opening reception and the closing banquet. 2 NINTH MEETING PROGRAM AND ABSTRACTS SRBR Information and Message Desk The Society will maintain an information desk in the Great Room of the Whistler Conference Centre from 8:00 to 11:00 on June 24–26, and from 15:00 to 17:00 on June 24–25. Late arrivals can register during these times. A message board will be located next to the information desk. Meeting participants are asked to check the message board routinely for mail, notes, and telephone messages. About the Village Whistler is nestled amongst the spectacular Coast Mountains of British Columbia, Canada, only 120 kilometers/75 miles north of Vancouver. The charming alpine Village of Whistler is home of Whistler and Blackcomb Mountains. A cluster of glacier-fed lakes reflects the surrounding mountain peaks that embrace Whistler Village. In addition to famous restaurants, engaging nightlife, and a variety of shops, Whistler also offers a bounty of summer activities. Conference Centre Information The Whistler Conference Centre is conveniently located within walking distance of all conference hotels. All SRBR scientific sessions and social events will take place at the Centre. Instructions to Presenters A new set of posters will be presented each day. Posters should be set-up on the day of presentation between 8:00–10:00. The poster presentation schedule is listed in the scientific program schedule. Final poster session posters must be removed on Saturday, June 26 by 14:00. Slide talk presenters should give their slides (clearly numbered and in correct order) to the projectionist 15 minutes before the start of the session. Computer projectors will be set up in each meeting room. PowerPoint presenters should bring their data on PC-compatible zip disk or CD-rom to the registration area to be loaded onto a presentation laptop computer during the registration period on Thursday, June 24. Social Events The SRBR Opening Reception will begin at 19:00 on Wednesday, June 23 in the Great Room of the Whistler Conference Centre. A banquet for conference attendees and guests will be held in the Ballroom of the Whistler Conference Centre on Saturday, June 26 at 20:00. SOCIETY FOR RESEARCH ON BIOLOGICAL RHYTHMS 3 Schedule All events will occur in the Whistler Conference Centre unless otherwise noted. -Wednesday, June 23- 13:00 Workshop 19:00 Reception—Great Room -Thursday, June 24- 08:30–10:30 National Academy Symposium 1—Rainbow Theatre 10:30–11:00 Coffee Break—Great Room 11:00–13:00 Slide Sessions 1–3 1) Entrainment I—McGuire 2) Mathematical/Theoretical Biology of Clocks—Sky Ballroom B 3) Circadian Pacemaker Output—Rainbow Theatre 13:00–14:30 Lunch Break 13:00–14:30 Poster Session Setup Posters 138–223—Sea Ballroom 14:30–16:30 Symposium 3 Clinical Implications of Clock Function—Sky Ballroom A Symposium 3 From Clocks to Metabolism and Back—Sky Ballroom B 13:30–16:30 Workshop National Space Biomedical Research Institute Workshop: Circadian and Sleep Countermeasures for Spac Exploration NASA: National Space Biomedical Research Institute Workshop: Circadian and Sleep Countermeasures for Space Exploration—McGuire 16:30–17:00 Coffee Break—Great Room 17:00–18:00 Presidential Lecture Rae Silver—Sky Ballroom B 18:00–20:00 Dinner Break 20:00–22:00 Poster Session 1 Posters 138–223—Sea Ballroom 4 NINTH MEETING PROGRAM AND ABSTRACTS -Friday, June 25- 07:00 Poster Session Setup Posters 224–312—Sea Ballroom 08:30–10:30 Symposium 4 Circadian Control of Sleep—Rainbow Theatre Symposium 5 Phylogeny and Ecological Consequences of Biological Clocks—Sky Ballroom B 10:30–11:00 Coffee Break—Great Room 11:00–13:00 Slide Sessions 4–6 4) Circadian Regulation of Photoreceptor—McGuire 5) Infraction Rhythms—Sky Ballroom A 6) Integration of Pacemaker Function—Rainbow Theatre 7) Genomic and Pharmacological Analyses of Sleep—Sky Ballroom B 13:00–14:30 Lunch Break 14:30–16:30 Symposium 6 Photoperiodic Time Measurement-Molecular Mechanisms—Rainbow Theatre Symposium 6 Non-Clock Functions for Clock Genes—Sky Ballroom B 14:30–16:30 Workshop Very Large Phase Shifts of the Circadian Clock—McGuire 16:30–17:00 Coffee Break—Great Room 17:00–18:00 Aschoff-Pittendrigh Lecture—Sky Ballroom B 18:00–20:00 Dinner Break 20:00–22:00 Poster Session 2 Posters 224–312—Sea Ballroom SOCIETY FOR RESEARCH ON BIOLOGICAL RHYTHMS 5 Saturday, June 26- 08:30–10:30 Symposium 8 Circadian System