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All Designer Drugs, Old and New

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All Designer Drugs, Old and New ALL DESIGNER DRUGS, OLD AND NEW written by Marcus Weiblen editing help/additional info by roionsteroids of reddit.com/r/Drugs Updates continue as of may 7th, 2014. if anyone has any other citable / reliable sources about any of these compounds or any other new drugs please let me know at marcus [dot] weiblen (at) gmail {dot} com and i'll try to keep this document updated throughout my hectic life. the document will to continue update here (if possible): https://www.dropbox.com/s/rzx3wpxfwuv2kww/designerdrugs.pdf (return to contents) CONTENTS: Foreword A Short Glossary / How to Read This Paper I: Stimulants / Empathogens (Dopamine/Noradrenaline Reuptake Inhibitors, 5-HT Releasers/Receptor Agonists) A. Substituted Cathinones B. Pyrrolidines/Pyrrolidinophenones C. Benzofurans D. Phenylpropylamines/piperidines E. Substituted Amphetamines F. Indanes/indoles G. Tropanes/*caines H. Piperazines I. Miscellaneous stimulants II: Psychedelic Hallucinogens (Serotonin 5-HT Receptor 2x Agonists) A. Phenethylamines 1. 2C-x series 2. Psychedelic Amphetamines 3. N-benzylated phenethylamines 4. Mescaline analogues 5. Conformationally-restricted derivatives B. Tryptamines 1. N-alkylated 2. 4-position substitutions 3. 5-position substitutions 4. LSD derivatives 5. alpha-position substitutions 6. 2-position substitutions 2 (return to contents) III: Sedatives (GABA Agonists / Modulators) IV: Analgesics (µ-Opioid Receptor Agonists) V: Synthetic Cannabinoids (CB /CB Agonists) 1 2 A. JWH series B. AM series C. Miscellaneous cannabinoids D. THJ series E. Endocannabinoid reuptake inhibitors VI: Dissociative Hallucinogens (NMDA Receptor Antagonists) VII: Test Kit Results VIII: References ---------- 3 (return to contents) FOREWORD - some speculation present, but any injuries/deaths mentioned are cited. “A controlled substance analogue shall, to the extent intended for human consumption, be treated, for the purposes of any Federal law as a controlled substance in schedule I.”[44] Over the past 40 years, a plethora of new drugs have appeared, using loopholes in drug legislation to fill the demand for the experiences provided by hallucinogens, stimulants, sedatives, and opioids that have already been made illegal. These drugs may be slight variations of a drug already scheduled (in the way that 5-MeO-DMT is a slight modification of DMT, adding a methoxy group to the 5-position) or they could be entirely new drugs, bearing no resemblance to known drugs, that happen to have desirable action (such as 7-hydroxy-mitragynine, an opioid found in the leaves of the kratom tree of Southeast Asia). How can these drugs be legally made and sold to people? Well, let’s take a look at the Federal Analog Act, the law created to control designer drugs: “(32)(A) Except as provided in subparagraph (C), the term "controlled substance analogue" means a substance— (i) the chemical structure of which is substantially similar to the chemical structure of a controlled substance in schedule I or II; (ii) which has a stimulant, depressant, or hallucinogenic effect on the central nervous system that is substantially similar to or greater than the stimulant, depressant, or hallucinogenic effect on the central nervous system of a controlled substance in schedule I or II; or (iii) with respect to a particular person, which such person represents or intends to have a stimulant, depressant, or hallucinogenic effect on the central nervous system that is substantially similar to or greater than the stimulant, depressant, or hallucinogenic effect on the central nervous system of a controlled substance in schedule I or II. 4 (return to contents) (B) The designation of gamma butyrolactone or any other chemical as a listed chemical pursuant to paragraph (34) or (35) does not preclude a finding pursuant to subparagraph (A) of this paragraph that the chemical is a controlled substance analogue. (C) Such term does not include— (i) a controlled substance; (ii) any substance for which there is an approved new drug application; (iii) with respect to a particular person any substance, if an exemption is in effect for investigational use, for that person, under section 355 of this title to the extent conduct with respect to such substance is pursuant to such exemption; or (iv) any substance to the extent not intended for human consumption before such an exemption takes effect with respect to that substance.”[45] Emphasis mine. What does this mean? According to the Federal Analog Act, these designer drugs, with effects equal to (or more powerful than) Schedule I & II drugs, can be sold as long as they are sold in a way that doesn’t suggest human consumption, such as selling it as “incense,” “bath salts,” “potpourri,” “plant food,” or some other innocuous-sounding product. You wouldn’t smoke and inhale incense, you wouldn’t eat bath salts, but that’s how the drug is sold to you. And if you want to try to find out about effects, dosage, or health risks from the vendor who sold it to you, they can’t tell you because doing so implies human consumption. Even if you buy the pure chemical by itself instead of in some blend (usually online, in which case it’s sold as a “research chemical”), you can’t ask the vendor about effects, dosage, or risks. You also can’t be sure of the purity of the drug or if it’s free of contaminants or impurities. The people making or selling the drugs are forbidden to tell the consumers about negative effects. It’s illegal to inform them about the drug, but it’s legal to sell it to them. 5 (return to contents) When you have a large amount of drug consumers who are unable to buy or use illegal drugs (probation, drug testing, or just can’t find any), many of them will find the convenience of legally purchasing a drug at a gas station or having it delivered to their door and still being able to pass their drug tests to be quite alluring. However, the sharing of knowledge about the effects, dosages, and health risks of these hundreds of new drugs that are sold in gas stations across the USA and internet vendors all over the world is illegal because the act of sharing of this information implies human consumption. People aren’t just trying synthetic marijuana, either. They’re doing Ecstasy (MDMA) analogs, amphetamine analogs for a cocaine-like high, using PCP analogs or MXE for euphoria and hallucinations, or using sometimes lethal hallucinogens to have experiences similar to those of LSD. People are trying these drugs, people are using these drugs, and at least 12 of these people have had acute kidney injury from certain cannabinoids,[36] over 50 people have died from overdosing on heroin adulterated with acetylfentanyl,[12][87][98] 9 people in Sweden died eating ground kratom leaves adulterated with a Tramadol analogue,[56] 14 more died from a strong stimulant,[8] powerful neurotoxins have been placed in “legal party pills”,[13][17] super-potent hallucinogens have killed at least 8 people,[7] fentanyl analogs are being used in fake prescription painkillers, [62] and more negative incidents that haven’t been reported. All because the communication of information about the drug that they’re using or even which one it is that they’re using is prohibited. This is happening in a time where naloxone is, as of February 2014, $42 per kit, demand for it is escalating sharply,[73] higher doses of it are needed to combat the stronger opioids now being sold,[74][77] and its accessibility is being delayed by fickle politics.[78] This document is a catalogue of all of the novel psychoactive compounds that I’m aware of, along with as much concrete, citable 6 (return to contents) information I can find about their potency, dosage, and health risks. It is an attempt to communicate this information to medical professionals, to help them treat people suffering from the problems some of these drugs can cause, and to try to prevent people from dying from these drugs. 7 (return to contents) A SHORT GLOSSARY / HOW TO READ THIS PAPER RC - research chemical Empathogen - “A class of psychoactive drugs that produce distinctive emotional and social effects similar to those of MDMA[…] users of empathogens say the drugs often produce feelings of empathy, love, and emotional closeness to others.” - Wikipedia MAOI - Monoamine oxidase inhibitor safeorscam.com - A website that contains a database of vendor names. You enter the website name or email address of the vendor and you'll be able to see reports from other people about the vendor’s quality of service and the quality of their drugs. You can NOT see a list of vendors on this website, you can only find information on vendors whose web address you already know. http://pdsp.med.unc.edu/pdsp.php - Lets you look up chemicals by receptor affinity. http://ecstasydata.org - reveals the contents of street/internet- sourced chemicals, many RCs show up here http://www.dancesafe.org - sells test kits to test MDMA or whatever chemical you have http://bunkpolice.org - same as above 8 (return to contents) If you want further information about any of these chemicals, you can look them up at https://www.erowid.org/psychoactives/psychoactives.shtml, [0] http://www.bluelight.org/, http://reddit.com/r/drugs or http://drugs- forum.com. The forums are full of people testing/enjoying these drugs themselves, so be warned some of them may be unreliable narrators. The use of straight brackets [] represents an information reference, while the use of curly brackets {} represents a picture of test kit results. The drugs described can have several different names. When one is underlined, that is to show the name that is most commonly used to refer to the drug, in speech and in text.
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