Equine Genetic Testing Report

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Generated On: 6/8/2018 1336 Timberlane Road Tallahassee, FL 32312-1766 Equine Genetic Testing Report Submitted By Terry & Deb Hochhalter Circle H Paints and Quarters P.O. Box 704 Linton, ND 58552 Subject Horse Date Received: 6/1/2018 Horse Name: Stingers Mis April Lab Reference #: 00110458 Breed: Paint Horse Registration: 331,061 Phenotype: Buckskin & White Tobiano Birth: 1996 Sex: Mare Sire Dam Sire Name: Dam Name: Breed: Breed: Registration: Registration: Phenotype: Phenotype: Coat Color and Pattern Testing Genetic Disorders Heterozygous. Horse carries one copy of the Tobiano Clear: Negative for the HYPP gene mutation. X Tobiano nT gene. X HYPP n/n Negative for Frame Overo (LWO). Clear: Negative for the HERDA gene mutation. X Frame Overo nn X HERDA N/N Negative for the Sabino 1 gene. Clear: Negative for the GBED gene mutation. X Sabino 1 nn X GBED N/N Negative for the Splashed White SW1 mutation. Clear: Negative for the MH gene mutation found in X Splashed White 1 nn X MH n/n Quarter horses and related breeds. Negative for the Splashed White SW2 mutation. Clear: Negative for the PSSM Type 1 gene mutation. X Splashed White 2 nn X PSSM 1 n/n Negative for the Splashed White SW3 mutation. Not Tested X Splashed White 3 nn FIS Tested negative for the main Appaloosa LP gene and is Not Tested Appaloosa (LP) JEB1 X lp/lp NOT affected by CSNB. Negative: Horse does not the carry the PATN-1 gene Not Tested PATN1 JEB2 X n/n mutation. Not Tested Heterozygous. Horse is Black based but carries a CA X Red/Black Factor Ee recessive copy of the Red gene. Not Tested Heterozygous. Horse carries one copy of the Agouti LFS X Agouti Aa gene. Not Tested Heterozygous. Single dilute. Horse carries one copy of SCID X Cream Dilution nCr the Cream Dilution gene. Not Tested Negative for currently known markers associated with OAAM1 X Dun Dilution dd Dun Dilution. Not Tested Negative for Silver Dilution. HWSD X Silver Dilution nn Not Tested Negative for Champagne Dilution. WFFS1 X Champagne nn Negative for Pearl Dilution. X Pearl Dilution nn Genetic Marker Results Run Date: Not Tested Not Tested Gray - - - - - - - - ----------------- ------ AHT4 AHT5 ASB17 ASB2 ASB23 AME CA425UK - - - - - - - Additional Comments HMS3 HMS6 HMS7 HTG10 HTG4 LEX3 LEX33 None - - - - - - VHL20 UM011 HMS1 HMS2 HTG6 HTG7 Toll Free: 866.922.6436 Phone: 850.386.2973 Fax: 850.386.1146 Web: www.animalgenetics.com.

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I . the Color Gene C
THE ABC OF COLOR INHERITANCE IN HORSES W. E. CASTLE Division of Genetics, University of California, Berkeley, California Received October, 27, 1947 HE study of color inheritance in horses was begun in the early days of Tgenetics. Indeed many facts concerning it had already been established earlier, by DARWINin his book on “Variation of Animals and Plants under Domestication.” At irregular inteivals since then, new attempts have been made to collect and classify in terms of genetic factors the records contained in stud books concerning the colors of colts in relation to the colors of their sires and dams. A full bibliography is given by CREWand BuCHANAN-SMITH (19301. By such studies, we have acquired very full information as to what color a colt may be expected to have, when the color of its parents and grandparents is known. This knowledge is empirical rather than experimental in nature. For horses being slow breeding and expensive are rarely available for direct experi- mental study, such as can be made with the small laboratory mammals, mice, rats, rabbits and guinea pigs. We have definite information that color inheritance in horses involves the existence of mutant genes similar to those demonstrated by experimental studies to be involved in color inheritance of other mammals. But the horse genes have been given special names, as they were successively discovered, and it is difficult at present to correlate them with the better known names and geneic symbols used by the experimental breeders. The present paper is an attempt to make such a correlation. Just as in morphological studies comparative anatomy was found useful and still is used to establish homologies between systems of organs, so in mammalian genetics, a comparative study of gene action in the production of coat colors and color patterns may also be of value.
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Use of Genomic Tools to Discover the Cause of Champagne Dilution Coat Color in Horses and to Map the Genetic Cause of Extreme Lordosis in American Saddlebred Horses
University of Kentucky UKnowledge Theses and Dissertations--Veterinary Science Veterinary Science 2014 USE OF GENOMIC TOOLS TO DISCOVER THE CAUSE OF CHAMPAGNE DILUTION COAT COLOR IN HORSES AND TO MAP THE GENETIC CAUSE OF EXTREME LORDOSIS IN AMERICAN SADDLEBRED HORSES Deborah G. Cook University of Kentucky, [email protected] Right click to open a feedback form in a new tab to let us know how this document benefits ou.y Recommended Citation Cook, Deborah G., "USE OF GENOMIC TOOLS TO DISCOVER THE CAUSE OF CHAMPAGNE DILUTION COAT COLOR IN HORSES AND TO MAP THE GENETIC CAUSE OF EXTREME LORDOSIS IN AMERICAN SADDLEBRED HORSES" (2014). Theses and Dissertations--Veterinary Science. 15. https://uknowledge.uky.edu/gluck_etds/15 This Doctoral Dissertation is brought to you for free and open access by the Veterinary Science at UKnowledge. It has been accepted for inclusion in Theses and Dissertations--Veterinary Science by an authorized administrator of UKnowledge. For more information, please contact [email protected]. STUDENT AGREEMENT: I represent that my thesis or dissertation and abstract are my original work. Proper attribution has been given to all outside sources. I understand that I am solely responsible for obtaining any needed copyright permissions. I have obtained needed written permission statement(s) from the owner(s) of each third-party copyrighted matter to be included in my work, allowing electronic distribution (if such use is not permitted by the fair use doctrine) which will be submitted to UKnowledge as Additional File. I hereby grant to The University of Kentucky and its agents the irrevocable, non-exclusive, and royalty-free license to archive and make accessible my work in whole or in part in all forms of media, now or hereafter known.
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The Occurrence of Silver Dilution in Horse Coat Colours
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Basic Horse Genetics
ALABAMA A&M AND AUBURN UNIVERSITIES Basic Horse Genetics ANR-1420 nderstanding the basic principles of genetics and Ugene-selection methods is essential for people in the horse-breeding business and is also beneficial to any horse owner when it comes to making decisions about a horse purchase, suitability, and utilization. Before getting into the basics of horse-breeding deci- sions, however, it is important that breeders under- stand the following terms. Chromosome - a rod-like body found in the cell nucleus that contains the genes. Chromosomes occur in pairs in all cells, with the exception of the sex cells (sperm and egg). Horses have 32 pairs of chromo- somes, and donkeys have 31 pairs. Gene - a small segment of chromosome (DNA) that contains the genetic code. Genes occur in pairs, one Quantitative traits - traits that show a continuous on each chromosome of a pair. range of phenotypic variation. Quantitative traits Alleles - the alternative states of a particular gene. The usually are controlled by more than one gene pair gene located at a fixed position on a chromosome will and are heavily influenced by environmental factors, contain a particular gene or one of its alleles. Multiple such as track condition, trainer expertise, and nutrition. alleles are possible. Because of these conditions, quantitative traits cannot be classified into distinct categories. Often, the impor- Genotype - the genetic makeup of an individual. With tant economic traits of livestock are quantitative—for alleles A and a, three possible genotypes are AA, Aa, example, cannon circumference and racing speed. and aa. Not all of these pairs of alleles will result in the same phenotype because pairs may have different Heritability - the portion of the total phenotypic modes of action.
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Color Coat Genetics
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By Danne Honour
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EQUINE COAT COLORS and GENETICS by Erika Eckstrom
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Inheritance of White Colour in Alpacas — Identifying the Genes Involved —
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Coat Color Testing Application
American Morgan Horse Association, Inc. 4037 Iron Works Parkway, Suite 130, Lexington, KY 40511-8508 COAT COLOR TESTING (802) 985-4944 • Fax: (859) 287-3555 [email protected] APPLICATION www.morganhorse.com COAT COLOR TESTING IS OPTIONAL. If the horse being tested tests positive for a specific coat color gene, that information can be recorded on the horse’s registration certificate (a $25 printing fee applies). Horse’s Name: _____________________________________________________________________________________________________________________________________________ Registration Number: ____________________________________________________________________ AVAILABLE COAT COLOR TESTS FEES (check appropriate box) (See reverse for descriptions) Member Non-Member q Cream Dilution q Gray First Coat Color Test .............................................................................................. $40 o $125 o q Red Factor and Agouti q Splash Each additional Coat Color Test on same horse ................................................ $25 o $110 o RUSH FEE (charge per horse) ............................................................................$100 o $100 o q Sabino 1 q Dun *AMHA membership applications can be found at www.morganhorse.com or by contacting AMHA. q Silver q Dominant White Pattern Reissue certificate with coat color test results .................................................. $25 o $110 o (original certificate must be submitted) q Lethal White Overo I understand that upon receipt of this application and the
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Dachshund Coat Colours and Their Inheritance
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A Mutation in the MATP Gene Causes the Cream Coat Colour in the Horse ∗ Denis MARIAT , Sead TAOURIT, Gérard GUÉRIN
Genet. Sel. Evol. 35 (2003) 119–133 119 © INRA, EDP Sciences, 2003 DOI: 10.1051/gse:2002039 Original article A mutation in the MATP gene causes the cream coat colour in the horse ∗ Denis MARIAT , Sead TAOURIT, Gérard GUÉRIN Laboratoire de génétique biochimique et de cytogénétique, Département de génétique animale, Institut national de la recherche agronomique, Centre de Recherche de Jouy, 78352 Jouy-en-Josas Cedex, France (Received 12 August 2002; accepted 4 November 2002) Abstract – In horses, basic colours such as bay or chestnut may be partially diluted to buckskin and palomino, or extremely diluted to cream, a nearly white colour with pink skin and blue eyes. This dilution is expected to be controlled by one gene and we used both candidate gene and positional cloning strategies to identify the “cream mutation”. A horse panel including reference colours was established and typed for different markers within or in the neighbourhood of two candidate genes. Our data suggest that the causal mutation, a G to A transition, is localised in exon 2 of the MATP gene leading to an aspartic acid to asparagine substitution in the encoded protein. This conserved mutation was also described in mice and humans, but not in medaka. horse / coat colour / underwhite / cream / MATP 1. INTRODUCTION In mammals, coat colour is deﬁned by two pigments in the skin and the hair, the black eumelanin and red pheomelanin. The speciﬁc colour of an animal thus depends on the pattern, the geographical distribution of the two pigments on the body, and on the relative quantity of both pigments.
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Champagne Delusion
Champagne Delusion: Champagne Look-Alike Dilutions Carolyn Shepard Here at ICHR, we find ourselves in some interesting situations involving unusual horse colors. Until we can remove the perception from people’s minds that champagne is a “default” horse color (if we can’t figure out the color - it must be champagne), and replace that perception with the idea that champagne is a specific color GENE, and not just a set of symptoms (why, my horse shows every characteristic of a champagne, so it must be one!), we’ll keep getting stuck in this uncomfortable rut of trying to explain why a certain horse is NOT champagne. The main point of this article will be that a horse does NOT have every characteristic of a champagne-colored horse – if it does not have a champagne-colored parent. Cream Dilutes: The Bane of Our Existence It’s an unfortunate fact that a seemingly large proportion of palomino foals are born with pink skin and blue eyes. This is the most common condition that is mistaken for champagne. While it is true that “most” gold champagne foals are born a shade of red, and “most” palomino foals are born a shade of cream, peach or yellow, it is not unheard of for gold champagne foals to be born yellow, and palomino foals to be born red. So the overlap between them is considerable, and a person would be hard-pressed to tell which was which - unless they had parents to look at. In the case of mixed parentage - where there is both cream and champagne in the background - only time and cream gene testing will tell.
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