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Than Smell. COVID-19 Is Associated with Severe Impairment of Smell, Taste, and Chemesthesis Valentina Parma, Kathrin Ohla, Maria Veldhuizen, Masha Niv, Christine E

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Than Smell. COVID-19 Is Associated with Severe Impairment of Smell, Taste, and Chemesthesis Valentina Parma, Kathrin Ohla, Maria Veldhuizen, Masha Niv, Christine E More than smell. COVID-19 is associated with severe impairment of smell, taste, and chemesthesis Valentina Parma, Kathrin Ohla, Maria Veldhuizen, Masha Niv, Christine E. Kelly, Alyssa Bakke, Keiland Cooper, Cédric Bouysset, Nicola Pirastu, Michele Dibattista, et al. To cite this version: Valentina Parma, Kathrin Ohla, Maria Veldhuizen, Masha Niv, Christine E. Kelly, et al.. More than smell. COVID-19 is associated with severe impairment of smell, taste, and chemesthesis. Chemical Senses, Oxford University Press (OUP), 2020, 45 (7), pp.609-622. 10.1093/chemse/bjaa041. hal- 02911030 HAL Id: hal-02911030 https://hal.inrae.fr/hal-02911030 Submitted on 3 Aug 2020 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Distributed under a Creative Commons Attribution - NonCommercial - NoDerivatives| 4.0 International License See discussions, stats, and author profiles for this publication at: https://www.researchgate.net/publication/341260934 More than just smell - COVID-19 is associated with severe impairment of smell, taste, and chemesthesis Preprint · May 2020 DOI: 10.1101/2020.05.04.20090902 CITATIONS READS 4 1,530 122 authors, including: Valentina Parma Kathrin Ohla Temple University Forschungszentrum Jülich 80 PUBLICATIONS 423 CITATIONS 53 PUBLICATIONS 818 CITATIONS SEE PROFILE SEE PROFILE Masha Y Niv Christine Kelly Hebrew University of Jerusalem AbScent 120 PUBLICATIONS 2,284 CITATIONS 6 PUBLICATIONS 95 CITATIONS SEE PROFILE SEE PROFILE Some of the authors of this publication are also working on these related projects: Genome-wide molecular landscapes of HPV-positive and HPV-negative head and neck squamous cell carcinoma View project The role of visual and auditory deficits in human social relationships View project All content following this page was uploaded by Enrique Santamaría on 02 June 2020. The user has requested enhancement of the downloaded file. medRxiv preprint doi: https://doi.org/10.1101/2020.05.04.20090902.this version posted May 8, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license . 1 More than just smell - COVID-19 is associated with severe impairment of smell, taste, and chemesthesis Valentina Parma!∗, Kathrin Ohla#∗, Maria G. Veldhuizen$∗, Masha Y. Niv%, Christine E. Kelly&, Alyssa J. Bakke', Keiland W. Cooper(, Cédric Bouysset), Nicola Pirastu*, Michele Dibattista!+, RishemJit Kaur!!, Marco Tullio Liuzza!#, Marta Y. Pepino!$, Veronika Schöpf!%, Veronica Pereda-Loth!&, Shannon B. Olsson!', Richard C. Gerkin!(, Paloma Rohlfs Domínguez!), Javier Albayay!*, Michael C. Farruggia#+, Surabhi Bhutani#!, Alexander W. FJaeldstad##, Ritesh Kumar#$, Anna Menini#%, Moustafa Bensafi#&, Mari Sandell#', Iordanis Konstantinidis#(, Antonella Di Pizio#), Federica Genovese#*, Lina Öztürk$, Thierry Thomas-Danguin$+, Johannes Frasnelli$!, Sanne Boesveldt$#, Özlem Saatci$$, Luis R. Saraiva$%, Cailu Lin#*, Jérôme Golebiowski), Liang-Dar Hwang$&, Mehmet Hakan Ozdener#*, Maria Dolors Guàrdia$', Christophe Laudamiel$(, Marina Ritchie(, Jitka Trebická Fialová$), Jan Havlícek$), Denis Pierron$*, Eugeni Roura$&, Marta Navarro$&, Alissa A. Nolden%+, Juyun Lim%!, Katie L. Whitcroft%#, Lauren R. Colquitt#*, Camille Ferdenzi#&, Evelyn V. Brindha%$, Aytug Altundag%%, Alberto Macchi%&, Alexia Nunez-Parra%', Zara M. Patel%(, Sébastien Fiorucci), Carl M. Philpott%), Barry C. Smith%*, Johan N. Lundström&+, Carla Mucignat!*, Jane K. Parker&!, Mirjam van den Brink&#, Michael Schmuker#$, Florian Ph.S Fischmeister&$, Thomas Heinbockel&%, Vonnie D.C. Shields&&, Farhoud FaraJi&', Enrique Santamaría&(, William E.A. Fredborg&), Gabriella Morini&*, Jonas K. Olofsson&), Maryam Jalessi'+, Noam Karni'!, Anna D’Errico'#, Rafieh Alizadeh'$, Robert Pellegrino'%, Pablo Meyer'&, Caroline Huart'', Ben Chen'(, Graciela M. Soler'), Mohammed K.Alwashahi'*, AntJe Welge-Lüssen(+, Jessica Freiherr(!, Jasper H. B. de Groot(#, Hadar Klein%, Masako Okamoto($, Olagunju Abdulrahman((, Pamela Dalton#*, Carol H. Yan(), Vera V. Voznessenskaya(*, Jingguo Chen)+, Elizabeth A. Sell)!, Julie Walsh-Messinger)#, Nicholas S. Archer)$, Sachiko Koyama)%, Vincent Deary)&, S. Craig Roberts)', Hüseyin Yanik$, Samet Albayrak)(, Lenka Martinec Nováková)), IlJa CroiJmans(#, Patricia Portillo Mazal)*, Shima T. Moein*+, Eitan Margulis%, Coralie Mignot*!, SaJidxa Marinn1ño*#, DeJan Georgiev*$, Pavan K. Kaushik*%, Bettina Malnic*&, Hong Wang#*, Shima Seyed-Allaei*+, Nur Yoluk$, Sara Razzaghi*', Jeb M. Justice(', Diego Restrepo*(, GCCR(%, Danielle R. Reed#*, Thomas Hummel(&, Steven D. Munger(', John E. Hayes' * denotes equal contribution medRxiv preprint doi: https://doi.org/10.1101/2020.05.04.20090902.this version posted May 8, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license . 2 !Temple University, #Research Center Jülich, $Mersin University, %The Hebrew University of Jerusalem, &AbScent, 'The Pennsylvania State University, (University of California Irvine, )Université Côte d’Azur, *The University of Edinburgh, !+Università degli Studi di Bari A. Moro, !!CSIR-Central Scientific Instruments Organisation, !#“Magna Graecia” University of Catanzaro, !$University of Illinois at Urbana Champaign, !%Medical University of Vienna, !&Université de Toulouse, !'National Centre for Biological Sciences, Tata Institute of Fundamental Research, !(Arizona State University, !)University of Extremadura, !*University of Padova, #+Yale University School of Medicine, #!San Diego State University, ##Aarhus University, #$University of Hertfordshire, #%SISSA, International School for Advanced Studies, #&Lyon Neuroscience Research Center, CNRS UMR5292 - INSERM U1028 - University Lyon 1, #'University of Helsinki, University of Turku, #(Aristotle University, #)Leibniz-Institute for Food Systems Biology at the Technical University of Munich, #*Monell Chemical Senses Center, $+INRAE, $!Université du Québec √† Trois-Rivières, $#Wageningen University, $$Medical Science University, $%Sidra Medicine, $&The University of Queensland, $'IRTA, $(DreamAir Llc, $)Charles University, $*Université de Toulouse-CNRS, %+University of Massachusetts Amherst, %!Oregon State University, %#UCL, %$Karunya University, %%Biruni University, %&Italian Academy Of Rhinology - assi sette laghi Varese, %'Universidad de Chile, %(Stanford University School of Medicine, %)University of East Anglia, %*University of London, &+Karolinska Institutet, &!University of Reading, &#Maastricht University, &$University of Graz, &%Howard University College of Medicine, &&Fisher College of Science and Mathematics, Towson University, &'University of California San Diego Health, &(Navarrabiomed-IDISNA, &)Stockholm University, &*University of Gastronomic Sciences, '+The Five Senses Institute, Iran University of Medical Sciences, '!Hadassah Medical Center, '#Goethe Universit√§t Frankfurt, '$Iran University of Medical Sciences, '%University of Tennessee, '&IBM T.J. Watson Research Center, ''Cliniques universitaires Saint-Luc, Brussels, Belgium, '(Guangzhou Medical University, ')Buenos Aires University and GEOG (Grupo de Estudio de Olfato y Gusto), '*Sultan Qaboos University, (+University Hospital Basel, Basel, (!FAU Erlangen, (#Utrecht University, ($The University of Tokyo, (%, (&TU Dresden, ('University of Florida, ((The Federal University of Technology, Akure, Nigeria., ()University of California San Diego, (*Severtsov Institute of Ecology and Evolution RAS, )+Second Affiliated Hospital of Xi’an Jiaotong University, )!University of Pennsylvania, )#University of Dayton, )$The Commonwealth Scientific and Industrial Research Organisation (CSIRO), )%Indiana University, )&Northumbria University Newcastle, )'University of Stirling, )(Middle East Technical University, ))Charles University, Faculty of Humanities, )*Hospital Italiano de Buenos Aires, *+Institute for Research in Fundamental Sciences, *!Smell and Taste Center, Dresden, *#Centro de Otorrinolaringología Respira Libre, *$University Medical Centre LJublJana, *%Tata Institute of Fundamental Research, *&University of São Paulo, Brazil, *'Bilkent University, *(University of Colorado Anschutz Medical Campus medRxiv preprint doi: https://doi.org/10.1101/2020.05.04.20090902.this version posted May 8, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license . 3 Author note Correspondence concerning this article should be addressed to: Dr. John E. Hayes Department of Food Science Pennsylvania State University 220 Erickson Food Science Building University Park, PA 16802 USA Email: [email protected] Twitter: @TasteProf Keywords: olfaction, gustation, coronavirus, hyposmia,
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