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EPOS 2021 Vision 2020 - EPOS 2021 EPOS 2021 Vision 2020 - EPOS 2021 Final programme & Abstract book EPOS 2021 Virtual Conference 18 - 19 June 2021 www.epos2021.dk EPOS 2021 Vision 2020 - EPOS 2021 2 Contents Final programme . 3 Invited speaker abstracts . 5 Free paper presentations . 33 Rapid fire presentations . 60 Poster presentations . 70 Local organizing Committee: Conference chair: Lotte Welinder Dept. of Ophthalmology, Aalborg University Hospital Members: Dorte Ancher Larsen Dept. of Ophthalmology, Aarhus University Hospital Else Gade Dept. of Ophthalmology, University Hospital Odense Lisbeth Sandfeld Dept. of Ophthalmology, Zealand University Hospital, Roskilde Kamilla Rothe Nissen Dept. of Ophthalmology, Rigshospitalet, University Hospital of Copenhagen Line Kessel Dept. of Ophthalmology, Rigshospitalet (Glostrup), University Hospital of Copenhagen Helena Buch Heesgaard Copenhagen Eye and Strabismus Clinic, CFR Hospitals EPOS Board Members: Darius Hildebrand President Eva Larsson Secretary Christina Gehrt-Kahlert Treasurer Catherine Cassiman Anne Cees Houtman Matthieu Robert Sandra Valeina EPOS 2021 Programme 3 Friday 18 June 8.50-9.00 Opening, welcome remarks 9.00-10.15 Around ROP and prematurity - Part 1 Moderators: Eva Larsson (SE) and Lotte Welinder (DK) 9.00-9.10 L1 Visual impairment. National Danish Registry of visual Kamilla Rothe Nissen (DK) impairment and blindness? 9.10-9.20 L2 Epidemiology of ROP Gerd Holmström (SE) 9.20-9.40 L3 The premature child. Ethical issues in neonatal care Gorm Greisen (DK) 9.40-9.50 L4 Ocular development and visual functioning in prematures Birgit Lorenz (DE) 9.50-10.05 Free paper & rapid fire presentations (3 min each) 10.05-10.15 Live Q&A/Panel discussion 10.15-10.35 Coffee break, Posters and Exhibition 10.35-11.20 Around ROP and prematurity - Part 2 Moderators: Eva Larsson (SE) and Kamilla Rothe Nissen (DK) 10.35-10.50 L6 Visual perception in children in the Express study Kerstin Hellgren (SE) 10.50-11.00 L7 The new European Registry for Childhood Cataract (EuReCCa) Marie-José Tassignon (BE) 11.00-11.10 LEGO Dansk Blindesamfund (DBS) 11.10-11.20 Live Q&A/Panel discussion 11.20-11.50 Sponsored Symposium (Platinum sponsor) 11.50-12.10 Lunch, Posters and Exhibition 12.10-13.25 Surgery in the first year - Part 1 Moderators: Dorte Larsen (DK) and Darius Hildebrand (UK) 12.10-12.30 L8 Anterior segment surgery in babies Ken Nischal (US) 12.30-12.45 L9 ROP: follow up after intravitreal bevacizumab Grace Prakalapakorn (US) 12.45-12.55 L10 40 years of primary congenital glaucoma in Denmark Daniella Bach Holm (DK) 12.55-13.05 L11 Vitrectomy in children with ROP – to be or not to be in the Marek Prost (PL) treatment of ROP? Results of 1000 vitrectomies. 13.05-13.15 Free paper presentations (3 min each) 13.15-13.25 Live Q&A/Panel discussion 13.25-13.40 Coffee break, Posters and Exhibition 13.40-14.45 Surgery in the first year - Part 2 Moderators: Daniella Bach Holm (DK) and Sandra Valeina (LV) 13.40-13.50 L12 Craniosynostosis, who needs surgery and when Hanne Hove (DK) 13.50-14.00 L13 Simple repair of eyelid coloboma Peter Toft (DK) 14.00-14.20 L14 Video session Ken Nischal (US) and others 14.20-14.35 Free paper presentations (3 min each) 14.35-14.45 Live Q&A/Panel discussion 14.45-15.05 Sponsored Symposium (Gold sponsor) 15.10-16.00 General assembly All EPOS board members EPOS 2021 Programme 4 Saturday 19 June 9.00-10.15 Neuroophthalmology in babies Catherine Cassiman (BE) and Matthieu Robert (FR) 9.00-9.10 L15 Delayed visual maturation - what’s in a name? Ingele Casteels (NO) 9.10-9.20 L16 Signs of brain tumours in babies Sarah von Holstein (DK) 9.20-9.30 L17 Midline from eyes to brain: an evolutionary perspective Marcel ten Tusscher (BE) 9.30-9.40 L18 The Brain stem and corpus callosum Anne Cees Houtmann (BE) 9.40-9.50 L19 The optic nerve as a cause of visual impairment Robert Matthieu (FR) 9.50-10.05 Free paper presentations (3 min each) 10.05-10.15 Live Q&A/Panel discussion 10.15-10.25 Coffee break, Posters and Exhibition 10.25-10.55 Sponsored Symposium (Platinum sponsor) 10.55-12.10 Pharmacological treatments & infectious diseases in Moderators: the first year Olivert Ehrt (D) and Lisbeth Sandfeld (DK) 10.55-11.05 L20 Tips and tricks to examining the baby Darius Hildebrand (UK) 11.05-11.15 L21 What to consider when using eye drops in babies Jens Chr. Nørregaard (DK) 11.15-11.25 L22 Steroids. Differences in pharmacokinetics between Regitze Bangsgaard (DK) different steroids, systemic side effects and influence of genetics 11.25-11.35 L23 Congenital Zika and the Eyes Grace Prakalapakorn (US) 11.35-11.50 Free paper presentations (3 min each) 11.50-12.10 Live Q&A/Panel discussion 12.10-12.50 Lunch, Posters and Exhibition 12.50-14.10 The baby who doesn't see - Part 1 Moderators: Line Kessel (DK) and Christina Gerth-Kahlert (CH) 12.50-13.10 L24 The critical role of high-fidelity visual input in the Agnes Wong (CA) development of audiovisual integration as revealed in amblyopia." 13.10-13.20 L25 Lebers congenital amaurosis and retinal dystrophies in Mette Bertelsen (DK) young children 13.20-13.35 L26 Gene therapy Bart Leroy (BE/US) 13.35-13.45 L27 The role of early visual electrodiagnostics Manca Tekavcic Pompe (SLO) 13.45-14.00 Free paper presentations (3 min each) 14.00-14.10 Live Q&A/Panel discussion 14.10-14.25 Coffee break, Posters and Exhibition 14.25-15.20 The baby who doesn't see - Part 2 Moderators: Else Gade (DK) and Anne Cees Houtman (NL) 14.25-14.40 L28 Early intervention for infants and very young children Naomi Dale (UK) with severe-profound visual impairment and share the scientific findings of our group.” 14.40-14.55 L29 Mother–infant interactions with infants with congenital Elena Sakkalou (UK) visual impairment and associations with longitudinal developmental outcomes 14.55-15.05 L30 Epidemiology and causes of nystagmus and lack of eye Line Kessel (DK) contact in babies 15.05-15.15 L31 Albinism Karen Grønskov (DK) 15.15-15.25 Live Q&A/Panel discussion 15.25-16.00 Closing remarks & Presentation of EPOS 2022 EPOS 2021 Invited Speaker Abstracts 5 [L1] VISUAL IMPAIRMENT. NATIONAL DANISH REGISTRY OF BLIND AND PARTIALLY SIGHTED CHILDREN Kamilla Rothe Nissen, Annette Rasmussen The study population was drawn from The Danish Registry for the Blind and Partially Sighted Children which is a national registry of all children (<18 years) with visual impairment or blindness. Defined as visual acuity ≤6/18, hemianopia or visual field <20 degrees on the better seeing eye. In addition, all children with progressive retinal disease must be registered at the time of diagnosis irrespective of visual function. The registry covers the years since 1970. Danish Registry for the Blind and Partially Sighted Children 31.12.2020. Total number of children: 1836 For the present study we included 1) Children < 1 year of age: N= 57. We focus on 2) The premature and the children with ROP seqvl at registration 2002-2020 Premature Children (Gestational age < 32 weeks or birth weight < 1500 g). Onehundred-and-sixtysix premature children of which ROP were described in 51 children were included. In conclusion • During the first year of life the primary cause of visual impairment in the Danish Registry is delayed visual maturation CVI 49%, congenital cataract 11%/ albinism 11% are the second common cause. Congenital nystagmus 9% is the third frequent cause. • ROP is noted in 2% of the diagnoses. • Among newly registered premature children the vision improved to withdrawal of the Registry (v.a.> 0.3) in 20% of the prematures and in 16% of the children with ROP. • In the group of prematures the majority is partially sighted 56%. Partially sight and blindness almost have the same frequency 43%/41% in children with ROP. • Visual impairment as a single disability was found in 23 % of the prematures and in 51 % of the children with ROP. Visual impairment and an additional disability was described in 77 % of the premature children and in 49% of the children with ROP. EPOS 2021 Invited Speaker Abstracts 6 [L2] EPIDEMIOLOGY OF ROP Gerd Holmström Dep Neuroscience, ophthalmology, University Hospital, Uppsala, Sweden Retinopathy of prematurity (ROP) remains an important cause of childhood blindness worldwide. Also, in countries like Sweden, where national screening programs have been available for decades, prematurely born infants go blind from ROP. The panorama of ROP is continuously changing and varies in different parts of the world. In developing countries, a third epidemic of ROP is evolving and very big babies may develop ROP. In highly developed countries, continuously improved neonatal care has resulted in increased survival of extremely immature babies with a high risk of very severe ROP, and, at the same time, a reduced incidence of ROP in the less immature babies, as illustrated in a recent Swedish study based on a national ROP register. Further, the most immature babies sometimes develop a central and rapidly progressing ROP requiring very prompt and efficient treatment. National screening programs for ROP are strongly recommended worldwide, to identify infants with severe ROP, to provide treatment at a correct time and to prevent prematurely born infants from going blind. Regarding inclusion criteria, however, such programs need to be adjusted to each country. EPOS 2021 Invited Speaker Abstracts 7 [L3] THE PREMATURE CHILD. ETHICAL ISSUES IN NEONATAL CARE Gorm Greisen Dept Neonatology, Rigshospitalet and Copenhagen University Being premature means being born before term, 3 weeks or more.
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