SERPINA9 Antibody

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Product Datasheet SERPINA9 Antibody Catalog No: #37387 Orders: [email protected] Description Support: [email protected] Product Name SERPINA9 Antibody Host Species Rabbit Clonality Polyclonal Purification Antigen affinity purification. Applications WB IHC Species Reactivity Hu Specificity The antibody detects endogenous levels of total SERPINA9 protein. Immunogen Type Peptide Immunogen Description Synthetic peptide corresponding to a region derived from internal residues of human serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 Target Name SERPINA9 Other Names GCET1; SERPINA11; SERPINA11b Accession No. Swiss-Prot#: Q86WD7NCBI Gene ID: 327657Gene Accssion: NP_001035983 SDS-PAGE MW 47kd Concentration 2.8mg/ml Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage Store at -20°C Application Details Western blotting: 1:500-1:2000 Immunohistochemistry: 1:50-1:200 Images Gel: 8%SDS-PAGE Lysates (from left to right): 293T and 231 cell, U937 and Raji cell Amount of lysate: 40ug per lane Primary antibody: 1/350 dilution Secondary antibody dilution: 1/8000 Exposure time: 10 seconds Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 1 Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #37387 at dilution 1/60. Background Serpin A9?also known as?centerin?or?GCET1?is a?protein?that in humans is encoded by the?SERPINA9?gene?located on?chromosome?14q32.1.[1]?Serpin A9 is a member of the?serpin?family of?serine?protease?inhibitors. The expression of SERPINA9 is restricted to germinal center B cells and lymphoid malignancies. SERPINA9 is likely to function in vivo in the germinal center as an efficient inhibitor of trypsin-like proteases. Highly expressed in normal germinal center (GC) B-cells and GC B-cell-derived malignancies. Note: This product is for in vitro research use only and is not intended for use in humans or animals. Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 2.

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Gene Symbol Category ACAN ECM ADAM10 ECM Remodeling-Related ADAM11 ECM Remodeling-Related ADAM12 ECM Remodeling-Related ADAM15 E
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Anti-SERPINA9 / GCET1 Antibody (ARG41824)
Product datasheet [email protected] ARG41824 Package: 100 μl anti-SERPINA9 / GCET1 antibody Store at: -20°C Summary Product Description Rabbit Polyclonal antibody recognizes SERPINA9 / GCET1 Tested Reactivity Hu, Ms, Rat Tested Application WB Host Rabbit Clonality Polyclonal Isotype IgG Target Name SERPINA9 / GCET1 Antigen Species Human Immunogen Synthetic peptide of Human SERPINA9 / GCET1. Conjugation Un-conjugated Alternate Names SERPINA11; Centerin; Germinal center B-cell-expressed transcript 1 protein; SERPINA11b; GCET1; Serpin A9 Application Instructions Application table Application Dilution WB 1:500 - 1:2000 Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. Positive Control MCF7 Calculated Mw 47 kDa Observed Size ~ 48 kDa Properties Form Liquid Purification Affinity purified. Buffer PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. Preservative 0.02% Sodium azide Stabilizer 50% Glycerol Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. Note For laboratory research only, not for drug, diagnostic or other use. www.arigobio.com 1/2 Bioinformation Gene Symbol SERPINA9 Gene Full Name serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 Function Protease inhibitor that inhibits trypsin and trypsin-like serine proteases (in vitro). Inhibits plasmin and thrombin with lower efficiency (in vitro). [UniProt] Cellular Localization Isoform 1: Secreted.
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Serpins—From Trap to Treatment
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Correlation of Serpin–Protease Expression by Comparative Analysis of Real-Time PCR Profiling Data
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(12) United States Patent (10) Patent No.: US 8,663,633 B2 Madison (45) Date of Patent: *Mar
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Egg serpins: The chicken and/or the egg dilemma Clara Dombre, Nicolas Guyot, Thierry Moreau, Philippe Monget, Mylène da Silva, Joël Gautron, Sophie Réhault-Godbert To cite this version: Clara Dombre, Nicolas Guyot, Thierry Moreau, Philippe Monget, Mylène da Silva, et al.. Egg serpins: The chicken and/or the egg dilemma. Seminars in Cell and Developmental Biology, Elsevier, 2017, 62, pp.120-132. 10.1016/j.semcdb.2016.08.019. hal-01595204 HAL Id: hal-01595204 https://hal.archives-ouvertes.fr/hal-01595204 Submitted on 27 May 2020 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Distributed under a Creative Commons Attribution - NonCommercial - NoDerivatives| 4.0 International License Seminars in Cell & Developmental Biology 62 (2017) 120–132 Contents lists available at ScienceDirect Seminars in Cell & Developmental Biology j ournal homepage: www.elsevier.com/locate/semcdb Review Egg serpins: The chicken and/or the egg dilemma a,b,c,d e f a,b,c,d Clara Dombre , Nicolas Guyot , Thierry Moreau , Philippe Monget , e e e,∗ Mylène Da Silva , Joël Gautron , Sophie Réhault-Godbert a INRA, UMR85 Physiologie de la Reproduction et des Comportements, F-37380 Nouzilly, France b CNRS, UMR6175 Physiologie de la Reproduction et des Comportements, F-37380 Nouzilly, France c Université Franc¸ ois Rabelais de Tours, F-37041 Tours, France d IFCE, F-37380 Nouzilly, France e INRA, UR83 Recherches Avicoles, F-37380 Nouzilly, France f CEPR, UMR INSERM U1100, Faculté de Médecine, Université de Tours, 10 Bd.
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Supplementary Table S1
SUPPLEMENTARY TABLE S1 Gene Symbol RefSeq Residues interrogated by amplicons ABL1 NM_005157.4 M237-E258 E275-K285 G303-L324 S348-H361 M388-F401 AKT1 NM_005163.2 G16-P24 L166-Y175 AKT2 NM_001626.4 G16-K20 I167-Y177 T292-G304 F369-A382 AKT3 NM_005465.4 G16-F27 K161-Y174 APC NM_00038.5 Q203-Q215 S280-L293 S295-H307 P865-L878 E1111-N1124 A1283-S1355 S1362-T1380 R1386-S1398 S1403-M1413S1421-P1433P1443-A1475E1530-S1539 E1554-K1561 BRAF NM_004333.4 K439-D445 Q461-H477 I582-F610 Q612-M620 CDH1 NM_004360.3 S337-P339 Y380-Q383 CDKN2A NM_000077.4 A13-R22 L32-A73 P75-L91 H98-R112 CSF1R NM_005211.3 S298-Q307 L964-C972 CTNNB1 NM_001904.3 D6-S45 EGFR NM_005228.3 I106-N115 P281-V292 P589-G601 V674-R686 A702-V726 G729-D761 E762-K823 R831-V843 Q849-L861 ERBB2 NM_004448.2 N302-P316 G462-P481 G668-Q680 K753-S779 V839-L852 ERBB3 NM_001982.3 E82-S95 N101-D112 F294-P306 C331-T342 F351-T366 W373-L384 I454-H466 G526-L536 T662-R675 L775-L796 K926-I938 T1169-L1177 D1259-P1272 ESR1 NM_000125.3 R300-D313 FBXW7 NM_033632.3 Q275-I281 T463-K472 H495-V507 H580-I593 FGFR1 NM_023110.2 A100-S115 P123-D132 E126-N143 R250-A263 P469-S477 FGFR2 NM_000141.4 R251-L262 P303-K313 P363-F387 K543-T555 L576-P594 N653-N662 FGFR3 NM_000142.4 R248-A261 E362-V393 V390-S408 Y648-N653 L690-E702 H791-S801 FGFR4 NM_002011 S123-D135 FLT3 NM_004119.2 D829-S840 GATA1 NM_002049.3 G7-V19 A68-P73 GNA11 NM_002067.3 G207-H218 GNAQ NM_002072.4 G207-H218 GNAS NM_001077488.2D197-L204 F209-F220 GSK3B NM_002093.3 D260-K271 HRAS NM_001130442.1V7-L19 A59-S65 IDH1 NM_005896.3 G123-Y135 IDH2 NM_002168.2 P162-Q178
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